Amino acid dipepetide frequency for Capybara microvirus Cap1_SP_66

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.378AlaAla: 3.378 ± 1.667
0.563AlaCys: 0.563 ± 1.206
1.689AlaAsp: 1.689 ± 0.489
3.941AlaGlu: 3.941 ± 2.656
1.689AlaPhe: 1.689 ± 1.804
3.941AlaGly: 3.941 ± 1.088
1.689AlaHis: 1.689 ± 0.93
0.563AlaIle: 0.563 ± 0.656
2.815AlaLys: 2.815 ± 1.262
11.261AlaLeu: 11.261 ± 3.362
1.126AlaMet: 1.126 ± 0.776
3.378AlaAsn: 3.378 ± 1.636
1.689AlaPro: 1.689 ± 1.059
2.252AlaGln: 2.252 ± 0.884
2.252AlaArg: 2.252 ± 0.932
6.757AlaSer: 6.757 ± 1.229
4.505AlaThr: 4.505 ± 2.075
3.941AlaVal: 3.941 ± 1.241
1.126AlaTrp: 1.126 ± 1.023
3.941AlaTyr: 3.941 ± 1.088
0.0AlaXaa: 0.0 ± 0.0
Cys
0.563CysAla: 0.563 ± 0.656
0.0CysCys: 0.0 ± 0.0
1.126CysAsp: 1.126 ± 1.176
0.563CysGlu: 0.563 ± 1.206
1.126CysPhe: 1.126 ± 0.776
0.563CysGly: 0.563 ± 0.482
0.563CysHis: 0.563 ± 0.482
0.0CysIle: 0.0 ± 0.0
0.563CysLys: 0.563 ± 0.656
2.252CysLeu: 2.252 ± 1.248
0.0CysMet: 0.0 ± 0.0
1.126CysAsn: 1.126 ± 0.776
1.126CysPro: 1.126 ± 0.466
0.0CysGln: 0.0 ± 0.0
0.563CysArg: 0.563 ± 0.388
1.126CysSer: 1.126 ± 1.214
1.126CysThr: 1.126 ± 1.023
0.563CysVal: 0.563 ± 0.388
0.0CysTrp: 0.0 ± 0.0
1.689CysTyr: 1.689 ± 1.611
0.0CysXaa: 0.0 ± 0.0
Asp
1.689AspAla: 1.689 ± 0.683
1.689AspCys: 1.689 ± 2.349
4.505AspAsp: 4.505 ± 0.948
6.194AspGlu: 6.194 ± 1.483
4.505AspPhe: 4.505 ± 1.612
4.505AspGly: 4.505 ± 2.087
1.126AspHis: 1.126 ± 0.466
3.378AspIle: 3.378 ± 1.365
3.941AspLys: 3.941 ± 1.088
3.941AspLeu: 3.941 ± 1.759
1.126AspMet: 1.126 ± 1.382
2.252AspAsn: 2.252 ± 1.306
0.563AspPro: 0.563 ± 0.388
0.563AspGln: 0.563 ± 0.388
1.689AspArg: 1.689 ± 1.142
3.941AspSer: 3.941 ± 2.065
1.126AspThr: 1.126 ± 0.545
6.757AspVal: 6.757 ± 1.826
0.0AspTrp: 0.0 ± 0.0
5.631AspTyr: 5.631 ± 2.121
0.0AspXaa: 0.0 ± 0.0
Glu
0.563GluAla: 0.563 ± 0.656
0.563GluCys: 0.563 ± 1.206
3.941GluAsp: 3.941 ± 2.115
1.689GluGlu: 1.689 ± 1.804
2.815GluPhe: 2.815 ± 1.304
3.378GluGly: 3.378 ± 2.907
0.563GluHis: 0.563 ± 0.944
2.252GluIle: 2.252 ± 1.931
2.815GluLys: 2.815 ± 1.047
2.815GluLeu: 2.815 ± 3.279
2.815GluMet: 2.815 ± 1.914
2.815GluAsn: 2.815 ± 1.364
1.126GluPro: 1.126 ± 1.073
1.689GluGln: 1.689 ± 0.866
1.689GluArg: 1.689 ± 0.95
3.941GluSer: 3.941 ± 1.241
0.563GluThr: 0.563 ± 0.482
2.815GluVal: 2.815 ± 0.738
0.0GluTrp: 0.0 ± 0.0
4.505GluTyr: 4.505 ± 0.902
0.0GluXaa: 0.0 ± 0.0
Phe
1.126PheAla: 1.126 ± 0.776
0.0PheCys: 0.0 ± 0.0
4.505PheAsp: 4.505 ± 1.835
1.689PheGlu: 1.689 ± 1.016
1.689PhePhe: 1.689 ± 0.894
2.252PheGly: 2.252 ± 1.044
2.252PheHis: 2.252 ± 0.924
1.689PheIle: 1.689 ± 0.866
1.689PheLys: 1.689 ± 1.055
6.757PheLeu: 6.757 ± 2.099
0.563PheMet: 0.563 ± 0.482
3.378PheAsn: 3.378 ± 1.441
2.815PhePro: 2.815 ± 1.135
0.563PheGln: 0.563 ± 1.206
2.815PheArg: 2.815 ± 0.933
2.252PheSer: 2.252 ± 1.801
2.815PheThr: 2.815 ± 1.729
3.941PheVal: 3.941 ± 1.35
0.563PheTrp: 0.563 ± 0.388
1.689PheTyr: 1.689 ± 1.164
0.0PheXaa: 0.0 ± 0.0
Gly
5.068GlyAla: 5.068 ± 1.646
0.0GlyCys: 0.0 ± 0.0
2.252GlyAsp: 2.252 ± 1.044
1.126GlyGlu: 1.126 ± 0.939
2.815GlyPhe: 2.815 ± 1.29
2.815GlyGly: 2.815 ± 0.738
0.0GlyHis: 0.0 ± 0.0
2.252GlyIle: 2.252 ± 1.197
3.941GlyLys: 3.941 ± 1.742
8.446GlyLeu: 8.446 ± 1.842
0.563GlyMet: 0.563 ± 0.388
3.941GlyAsn: 3.941 ± 2.254
0.0GlyPro: 0.0 ± 0.0
3.941GlyGln: 3.941 ± 1.428
1.126GlyArg: 1.126 ± 1.023
6.757GlySer: 6.757 ± 2.091
1.689GlyThr: 1.689 ± 0.709
4.505GlyVal: 4.505 ± 0.861
0.0GlyTrp: 0.0 ± 0.0
3.378GlyTyr: 3.378 ± 1.398
0.0GlyXaa: 0.0 ± 0.0
His
1.126HisAla: 1.126 ± 1.125
0.563HisCys: 0.563 ± 0.482
1.689HisAsp: 1.689 ± 1.909
1.126HisGlu: 1.126 ± 1.073
0.563HisPhe: 0.563 ± 0.388
1.126HisGly: 1.126 ± 0.466
0.563HisHis: 0.563 ± 0.388
0.563HisIle: 0.563 ± 0.656
1.126HisLys: 1.126 ± 0.776
2.252HisLeu: 2.252 ± 0.932
1.126HisMet: 1.126 ± 0.728
1.126HisAsn: 1.126 ± 0.965
1.126HisPro: 1.126 ± 0.939
1.126HisGln: 1.126 ± 1.697
1.126HisArg: 1.126 ± 0.9
2.252HisSer: 2.252 ± 0.805
0.563HisThr: 0.563 ± 0.482
0.563HisVal: 0.563 ± 0.388
0.0HisTrp: 0.0 ± 0.0
2.252HisTyr: 2.252 ± 1.322
0.0HisXaa: 0.0 ± 0.0
Ile
5.068IleAla: 5.068 ± 2.338
1.126IleCys: 1.126 ± 0.9
3.941IleAsp: 3.941 ± 3.141
1.126IleGlu: 1.126 ± 1.312
2.815IlePhe: 2.815 ± 1.206
5.068IleGly: 5.068 ± 1.155
0.563IleHis: 0.563 ± 0.388
1.689IleIle: 1.689 ± 1.401
3.941IleLys: 3.941 ± 2.346
2.815IleLeu: 2.815 ± 1.039
1.126IleMet: 1.126 ± 0.466
6.757IleAsn: 6.757 ± 1.764
4.505IlePro: 4.505 ± 1.815
1.689IleGln: 1.689 ± 0.866
4.505IleArg: 4.505 ± 1.591
3.378IleSer: 3.378 ± 1.072
5.068IleThr: 5.068 ± 1.386
2.252IleVal: 2.252 ± 1.14
0.0IleTrp: 0.0 ± 0.0
3.378IleTyr: 3.378 ± 1.596
0.0IleXaa: 0.0 ± 0.0
Lys
1.689LysAla: 1.689 ± 0.866
0.563LysCys: 0.563 ± 0.388
2.252LysAsp: 2.252 ± 1.091
5.068LysGlu: 5.068 ± 3.611
1.689LysPhe: 1.689 ± 0.709
1.126LysGly: 1.126 ± 0.9
1.689LysHis: 1.689 ± 1.138
6.757LysIle: 6.757 ± 1.777
2.252LysLys: 2.252 ± 1.551
3.378LysLeu: 3.378 ± 1.418
2.252LysMet: 2.252 ± 0.975
3.941LysAsn: 3.941 ± 2.365
2.815LysPro: 2.815 ± 1.047
2.815LysGln: 2.815 ± 1.157
4.505LysArg: 4.505 ± 1.341
2.252LysSer: 2.252 ± 1.467
2.252LysThr: 2.252 ± 2.143
1.126LysVal: 1.126 ± 0.9
0.0LysTrp: 0.0 ± 0.0
2.252LysTyr: 2.252 ± 0.924
0.0LysXaa: 0.0 ± 0.0
Leu
6.757LeuAla: 6.757 ± 2.265
1.126LeuCys: 1.126 ± 1.176
5.631LeuAsp: 5.631 ± 2.275
3.941LeuGlu: 3.941 ± 2.159
2.252LeuPhe: 2.252 ± 1.707
4.505LeuGly: 4.505 ± 1.659
1.689LeuHis: 1.689 ± 1.112
5.068LeuIle: 5.068 ± 0.817
5.068LeuLys: 5.068 ± 2.554
6.194LeuLeu: 6.194 ± 1.146
3.378LeuMet: 3.378 ± 0.837
9.009LeuAsn: 9.009 ± 2.485
7.32LeuPro: 7.32 ± 1.69
5.068LeuGln: 5.068 ± 0.827
3.378LeuArg: 3.378 ± 0.979
7.883LeuSer: 7.883 ± 2.662
3.378LeuThr: 3.378 ± 1.923
3.941LeuVal: 3.941 ± 2.298
1.689LeuTrp: 1.689 ± 0.95
3.378LeuTyr: 3.378 ± 0.975
0.0LeuXaa: 0.0 ± 0.0
Met
1.689MetAla: 1.689 ± 1.971
0.563MetCys: 0.563 ± 0.656
1.689MetAsp: 1.689 ± 1.967
1.126MetGlu: 1.126 ± 1.125
1.126MetPhe: 1.126 ± 0.466
1.689MetGly: 1.689 ± 1.164
0.0MetHis: 0.0 ± 0.0
1.689MetIle: 1.689 ± 1.059
1.126MetLys: 1.126 ± 0.466
0.563MetLeu: 0.563 ± 0.482
0.563MetMet: 0.563 ± 0.388
0.563MetAsn: 0.563 ± 0.972
1.689MetPro: 1.689 ± 0.683
2.252MetGln: 2.252 ± 1.044
1.689MetArg: 1.689 ± 0.683
3.378MetSer: 3.378 ± 1.072
2.252MetThr: 2.252 ± 1.552
2.252MetVal: 2.252 ± 0.916
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.815AsnAla: 2.815 ± 1.665
1.689AsnCys: 1.689 ± 0.866
3.378AsnAsp: 3.378 ± 1.299
2.252AsnGlu: 2.252 ± 1.552
2.815AsnPhe: 2.815 ± 0.695
4.505AsnGly: 4.505 ± 1.952
1.126AsnHis: 1.126 ± 0.545
2.252AsnIle: 2.252 ± 1.628
5.068AsnLys: 5.068 ± 1.212
6.194AsnLeu: 6.194 ± 3.166
1.689AsnMet: 1.689 ± 1.007
3.941AsnAsn: 3.941 ± 1.727
4.505AsnPro: 4.505 ± 1.922
3.378AsnGln: 3.378 ± 1.739
3.378AsnArg: 3.378 ± 1.552
2.252AsnSer: 2.252 ± 1.552
4.505AsnThr: 4.505 ± 1.485
6.194AsnVal: 6.194 ± 1.822
0.0AsnTrp: 0.0 ± 0.0
3.941AsnTyr: 3.941 ± 0.845
0.0AsnXaa: 0.0 ± 0.0
Pro
3.941ProAla: 3.941 ± 1.576
1.126ProCys: 1.126 ± 1.073
0.563ProAsp: 0.563 ± 0.482
2.252ProGlu: 2.252 ± 0.875
3.941ProPhe: 3.941 ± 1.385
0.0ProGly: 0.0 ± 0.0
2.252ProHis: 2.252 ± 0.999
7.883ProIle: 7.883 ± 1.025
1.126ProLys: 1.126 ± 0.545
3.941ProLeu: 3.941 ± 1.467
1.126ProMet: 1.126 ± 0.545
2.815ProAsn: 2.815 ± 0.695
1.126ProPro: 1.126 ± 0.965
3.378ProGln: 3.378 ± 0.815
0.563ProArg: 0.563 ± 0.482
5.631ProSer: 5.631 ± 1.917
3.378ProThr: 3.378 ± 0.928
3.941ProVal: 3.941 ± 1.739
0.563ProTrp: 0.563 ± 0.388
1.126ProTyr: 1.126 ± 0.776
0.0ProXaa: 0.0 ± 0.0
Gln
5.068GlnAla: 5.068 ± 1.103
0.0GlnCys: 0.0 ± 0.0
2.252GlnAsp: 2.252 ± 0.967
0.563GlnGlu: 0.563 ± 0.388
1.689GlnPhe: 1.689 ± 0.866
1.126GlnGly: 1.126 ± 1.1
0.563GlnHis: 0.563 ± 0.388
2.252GlnIle: 2.252 ± 1.983
2.252GlnLys: 2.252 ± 0.932
5.631GlnLeu: 5.631 ± 1.364
1.689GlnMet: 1.689 ± 0.683
5.068GlnAsn: 5.068 ± 2.727
2.252GlnPro: 2.252 ± 0.967
3.378GlnGln: 3.378 ± 2.284
2.252GlnArg: 2.252 ± 1.357
5.631GlnSer: 5.631 ± 1.285
4.505GlnThr: 4.505 ± 1.094
2.252GlnVal: 2.252 ± 0.967
0.563GlnTrp: 0.563 ± 0.656
0.563GlnTyr: 0.563 ± 0.388
0.0GlnXaa: 0.0 ± 0.0
Arg
2.252ArgAla: 2.252 ± 0.924
0.563ArgCys: 0.563 ± 0.388
2.815ArgAsp: 2.815 ± 1.135
2.252ArgGlu: 2.252 ± 1.091
2.815ArgPhe: 2.815 ± 1.729
2.815ArgGly: 2.815 ± 1.172
0.563ArgHis: 0.563 ± 0.388
2.252ArgIle: 2.252 ± 1.552
2.252ArgLys: 2.252 ± 0.492
4.505ArgLeu: 4.505 ± 1.946
0.563ArgMet: 0.563 ± 0.388
2.252ArgAsn: 2.252 ± 1.29
1.689ArgPro: 1.689 ± 1.138
3.378ArgGln: 3.378 ± 1.739
1.126ArgArg: 1.126 ± 0.545
1.689ArgSer: 1.689 ± 0.683
1.689ArgThr: 1.689 ± 0.962
3.941ArgVal: 3.941 ± 2.055
0.0ArgTrp: 0.0 ± 0.0
4.505ArgTyr: 4.505 ± 3.224
0.0ArgXaa: 0.0 ± 0.0
Ser
7.883SerAla: 7.883 ± 1.726
1.126SerCys: 1.126 ± 0.965
2.252SerAsp: 2.252 ± 1.248
1.689SerGlu: 1.689 ± 0.894
3.941SerPhe: 3.941 ± 2.716
5.068SerGly: 5.068 ± 2.793
1.126SerHis: 1.126 ± 0.466
6.194SerIle: 6.194 ± 1.462
4.505SerLys: 4.505 ± 1.637
6.757SerLeu: 6.757 ± 2.598
1.689SerMet: 1.689 ± 0.93
2.252SerAsn: 2.252 ± 1.467
5.631SerPro: 5.631 ± 1.971
6.194SerGln: 6.194 ± 2.516
3.378SerArg: 3.378 ± 1.299
3.941SerSer: 3.941 ± 1.629
5.631SerThr: 5.631 ± 1.8
5.068SerVal: 5.068 ± 1.611
0.563SerTrp: 0.563 ± 0.656
3.378SerTyr: 3.378 ± 1.366
0.0SerXaa: 0.0 ± 0.0
Thr
7.32ThrAla: 7.32 ± 3.138
0.0ThrCys: 0.0 ± 0.0
3.378ThrAsp: 3.378 ± 1.365
1.689ThrGlu: 1.689 ± 0.683
5.631ThrPhe: 5.631 ± 1.622
2.815ThrGly: 2.815 ± 1.172
1.126ThrHis: 1.126 ± 0.965
5.631ThrIle: 5.631 ± 0.964
1.689ThrLys: 1.689 ± 0.709
3.378ThrLeu: 3.378 ± 1.297
2.815ThrMet: 2.815 ± 1.038
2.252ThrAsn: 2.252 ± 0.492
3.378ThrPro: 3.378 ± 1.476
1.126ThrGln: 1.126 ± 0.545
0.563ThrArg: 0.563 ± 0.944
3.941ThrSer: 3.941 ± 1.428
5.631ThrThr: 5.631 ± 2.12
0.563ThrVal: 0.563 ± 0.388
0.0ThrTrp: 0.0 ± 0.0
5.068ThrTyr: 5.068 ± 1.668
0.0ThrXaa: 0.0 ± 0.0
Val
2.815ValAla: 2.815 ± 0.917
1.126ValCys: 1.126 ± 0.466
4.505ValAsp: 4.505 ± 2.838
2.252ValGlu: 2.252 ± 1.959
0.0ValPhe: 0.0 ± 0.0
3.941ValGly: 3.941 ± 0.901
1.689ValHis: 1.689 ± 0.866
3.378ValIle: 3.378 ± 0.788
0.563ValLys: 0.563 ± 0.388
5.631ValLeu: 5.631 ± 2.595
1.126ValMet: 1.126 ± 0.466
5.068ValAsn: 5.068 ± 1.771
3.941ValPro: 3.941 ± 1.584
2.815ValGln: 2.815 ± 0.738
3.378ValArg: 3.378 ± 0.975
6.194ValSer: 6.194 ± 1.146
4.505ValThr: 4.505 ± 1.288
2.815ValVal: 2.815 ± 0.695
0.563ValTrp: 0.563 ± 0.972
3.378ValTyr: 3.378 ± 1.138
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.563TrpCys: 0.563 ± 0.656
2.252TrpAsp: 2.252 ± 1.552
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.126TrpIle: 1.126 ± 1.125
0.0TrpLys: 0.0 ± 0.0
0.563TrpLeu: 0.563 ± 0.482
0.0TrpMet: 0.0 ± 0.0
0.563TrpAsn: 0.563 ± 0.972
0.0TrpPro: 0.0 ± 0.0
1.126TrpGln: 1.126 ± 0.734
0.0TrpArg: 0.0 ± 0.0
0.563TrpSer: 0.563 ± 0.944
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.563TrpTrp: 0.563 ± 0.656
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.689TyrAla: 1.689 ± 0.866
1.689TyrCys: 1.689 ± 1.164
4.505TyrAsp: 4.505 ± 1.288
2.815TyrGlu: 2.815 ± 1.246
1.126TyrPhe: 1.126 ± 0.965
3.378TyrGly: 3.378 ± 1.418
2.815TyrHis: 2.815 ± 1.923
3.941TyrIle: 3.941 ± 3.085
3.941TyrLys: 3.941 ± 1.825
3.378TyrLeu: 3.378 ± 1.923
0.0TyrMet: 0.0 ± 0.0
3.941TyrAsn: 3.941 ± 0.896
3.378TyrPro: 3.378 ± 1.398
2.815TyrGln: 2.815 ± 1.039
3.941TyrArg: 3.941 ± 1.029
4.505TyrSer: 4.505 ± 1.719
2.815TyrThr: 2.815 ± 1.406
2.252TyrVal: 2.252 ± 1.12
1.126TyrTrp: 1.126 ± 0.466
3.378TyrTyr: 3.378 ± 1.398
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1777 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski