Amino acid dipepetide frequency for Fundicoccus ignavus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.201AlaAla: 6.201 ± 0.183
0.459AlaCys: 0.459 ± 0.03
4.333AlaAsp: 4.333 ± 0.112
5.587AlaGlu: 5.587 ± 0.107
3.337AlaPhe: 3.337 ± 0.071
5.371AlaGly: 5.371 ± 0.092
1.318AlaHis: 1.318 ± 0.042
6.35AlaIle: 6.35 ± 0.103
4.363AlaLys: 4.363 ± 0.093
7.883AlaLeu: 7.883 ± 0.118
2.197AlaMet: 2.197 ± 0.06
3.667AlaAsn: 3.667 ± 0.086
2.069AlaPro: 2.069 ± 0.062
3.121AlaGln: 3.121 ± 0.085
2.961AlaArg: 2.961 ± 0.08
4.742AlaSer: 4.742 ± 0.09
4.306AlaThr: 4.306 ± 0.07
5.35AlaVal: 5.35 ± 0.1
0.652AlaTrp: 0.652 ± 0.03
2.822AlaTyr: 2.822 ± 0.063
0.0AlaXaa: 0.0 ± 0.0
Cys
0.329CysAla: 0.329 ± 0.021
0.057CysCys: 0.057 ± 0.01
0.259CysAsp: 0.259 ± 0.018
0.344CysGlu: 0.344 ± 0.022
0.228CysPhe: 0.228 ± 0.019
0.497CysGly: 0.497 ± 0.031
0.171CysHis: 0.171 ± 0.015
0.344CysIle: 0.344 ± 0.021
0.163CysLys: 0.163 ± 0.017
0.498CysLeu: 0.498 ± 0.028
0.109CysMet: 0.109 ± 0.011
0.192CysAsn: 0.192 ± 0.015
0.202CysPro: 0.202 ± 0.016
0.217CysGln: 0.217 ± 0.02
0.227CysArg: 0.227 ± 0.018
0.309CysSer: 0.309 ± 0.023
0.184CysThr: 0.184 ± 0.016
0.298CysVal: 0.298 ± 0.019
0.043CysTrp: 0.043 ± 0.007
0.166CysTyr: 0.166 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
4.074AspAla: 4.074 ± 0.075
0.248AspCys: 0.248 ± 0.02
2.85AspAsp: 2.85 ± 0.071
4.793AspGlu: 4.793 ± 0.094
2.794AspPhe: 2.794 ± 0.067
3.528AspGly: 3.528 ± 0.11
1.004AspHis: 1.004 ± 0.044
4.303AspIle: 4.303 ± 0.074
2.823AspLys: 2.823 ± 0.072
5.675AspLeu: 5.675 ± 0.098
1.382AspMet: 1.382 ± 0.045
2.505AspAsn: 2.505 ± 0.065
1.807AspPro: 1.807 ± 0.048
2.342AspGln: 2.342 ± 0.059
2.129AspArg: 2.129 ± 0.057
3.216AspSer: 3.216 ± 0.078
2.89AspThr: 2.89 ± 0.071
3.858AspVal: 3.858 ± 0.075
0.661AspTrp: 0.661 ± 0.036
2.875AspTyr: 2.875 ± 0.064
0.0AspXaa: 0.0 ± 0.0
Glu
6.869GluAla: 6.869 ± 0.118
0.278GluCys: 0.278 ± 0.022
3.965GluAsp: 3.965 ± 0.075
6.463GluGlu: 6.463 ± 0.157
2.906GluPhe: 2.906 ± 0.072
4.061GluGly: 4.061 ± 0.099
1.452GluHis: 1.452 ± 0.052
5.634GluIle: 5.634 ± 0.087
4.39GluLys: 4.39 ± 0.094
7.624GluLeu: 7.624 ± 0.109
2.148GluMet: 2.148 ± 0.057
3.791GluAsn: 3.791 ± 0.069
2.047GluPro: 2.047 ± 0.059
3.38GluGln: 3.38 ± 0.071
3.199GluArg: 3.199 ± 0.067
4.058GluSer: 4.058 ± 0.092
4.779GluThr: 4.779 ± 0.105
5.789GluVal: 5.789 ± 0.114
0.72GluTrp: 0.72 ± 0.035
2.453GluTyr: 2.453 ± 0.062
0.0GluXaa: 0.0 ± 0.0
Phe
3.078PheAla: 3.078 ± 0.069
0.241PheCys: 0.241 ± 0.017
2.926PheAsp: 2.926 ± 0.07
3.334PheGlu: 3.334 ± 0.068
1.96PhePhe: 1.96 ± 0.072
3.057PheGly: 3.057 ± 0.075
0.77PheHis: 0.77 ± 0.035
3.347PheIle: 3.347 ± 0.088
2.47PheLys: 2.47 ± 0.062
3.845PheLeu: 3.845 ± 0.1
1.126PheMet: 1.126 ± 0.041
2.431PheAsn: 2.431 ± 0.064
1.419PhePro: 1.419 ± 0.048
1.598PheGln: 1.598 ± 0.051
1.491PheArg: 1.491 ± 0.044
2.99PheSer: 2.99 ± 0.067
2.487PheThr: 2.487 ± 0.06
3.151PheVal: 3.151 ± 0.068
0.39PheTrp: 0.39 ± 0.026
1.792PheTyr: 1.792 ± 0.055
0.0PheXaa: 0.0 ± 0.0
Gly
4.6GlyAla: 4.6 ± 0.102
0.377GlyCys: 0.377 ± 0.023
3.241GlyAsp: 3.241 ± 0.074
4.259GlyGlu: 4.259 ± 0.093
3.014GlyPhe: 3.014 ± 0.067
4.321GlyGly: 4.321 ± 0.099
1.311GlyHis: 1.311 ± 0.046
5.168GlyIle: 5.168 ± 0.093
3.642GlyLys: 3.642 ± 0.086
6.464GlyLeu: 6.464 ± 0.104
1.86GlyMet: 1.86 ± 0.057
2.709GlyAsn: 2.709 ± 0.079
1.59GlyPro: 1.59 ± 0.05
2.695GlyGln: 2.695 ± 0.068
2.688GlyArg: 2.688 ± 0.068
3.901GlySer: 3.901 ± 0.081
3.66GlyThr: 3.66 ± 0.08
4.959GlyVal: 4.959 ± 0.093
0.649GlyTrp: 0.649 ± 0.029
2.75GlyTyr: 2.75 ± 0.068
0.0GlyXaa: 0.0 ± 0.0
His
1.352HisAla: 1.352 ± 0.045
0.139HisCys: 0.139 ± 0.015
1.19HisAsp: 1.19 ± 0.058
1.313HisGlu: 1.313 ± 0.042
1.026HisPhe: 1.026 ± 0.04
1.256HisGly: 1.256 ± 0.052
0.62HisHis: 0.62 ± 0.04
1.243HisIle: 1.243 ± 0.046
0.866HisLys: 0.866 ± 0.036
2.045HisLeu: 2.045 ± 0.059
0.436HisMet: 0.436 ± 0.026
0.878HisAsn: 0.878 ± 0.037
1.02HisPro: 1.02 ± 0.039
1.02HisGln: 1.02 ± 0.039
0.862HisArg: 0.862 ± 0.04
1.124HisSer: 1.124 ± 0.046
1.029HisThr: 1.029 ± 0.042
1.19HisVal: 1.19 ± 0.044
0.187HisTrp: 0.187 ± 0.016
0.962HisTyr: 0.962 ± 0.036
0.0HisXaa: 0.0 ± 0.0
Ile
6.22IleAla: 6.22 ± 0.088
0.461IleCys: 0.461 ± 0.025
4.728IleAsp: 4.728 ± 0.076
6.289IleGlu: 6.289 ± 0.1
3.067IlePhe: 3.067 ± 0.08
5.189IleGly: 5.189 ± 0.1
1.47IleHis: 1.47 ± 0.044
5.708IleIle: 5.708 ± 0.119
4.12IleLys: 4.12 ± 0.093
7.074IleLeu: 7.074 ± 0.134
1.797IleMet: 1.797 ± 0.056
3.809IleAsn: 3.809 ± 0.082
2.882IlePro: 2.882 ± 0.067
3.102IleGln: 3.102 ± 0.068
2.826IleArg: 2.826 ± 0.069
4.816IleSer: 4.816 ± 0.099
4.143IleThr: 4.143 ± 0.085
5.581IleVal: 5.581 ± 0.091
0.606IleTrp: 0.606 ± 0.029
2.725IleTyr: 2.725 ± 0.07
0.0IleXaa: 0.0 ± 0.0
Lys
4.341LysAla: 4.341 ± 0.093
0.196LysCys: 0.196 ± 0.015
3.023LysAsp: 3.023 ± 0.064
4.743LysGlu: 4.743 ± 0.092
1.893LysPhe: 1.893 ± 0.056
3.139LysGly: 3.139 ± 0.07
1.234LysHis: 1.234 ± 0.05
3.886LysIle: 3.886 ± 0.078
3.251LysLys: 3.251 ± 0.074
4.898LysLeu: 4.898 ± 0.08
1.623LysMet: 1.623 ± 0.04
2.492LysAsn: 2.492 ± 0.068
1.694LysPro: 1.694 ± 0.046
2.869LysGln: 2.869 ± 0.076
2.642LysArg: 2.642 ± 0.075
2.759LysSer: 2.759 ± 0.067
2.95LysThr: 2.95 ± 0.072
4.042LysVal: 4.042 ± 0.088
0.498LysTrp: 0.498 ± 0.029
1.985LysTyr: 1.985 ± 0.065
0.0LysXaa: 0.0 ± 0.0
Leu
8.632LeuAla: 8.632 ± 0.164
0.436LeuCys: 0.436 ± 0.028
5.643LeuAsp: 5.643 ± 0.094
7.057LeuGlu: 7.057 ± 0.112
4.237LeuPhe: 4.237 ± 0.1
6.261LeuGly: 6.261 ± 0.098
1.47LeuHis: 1.47 ± 0.055
7.389LeuIle: 7.389 ± 0.139
5.679LeuLys: 5.679 ± 0.093
10.021LeuLeu: 10.021 ± 0.149
2.726LeuMet: 2.726 ± 0.062
5.187LeuAsn: 5.187 ± 0.087
3.882LeuPro: 3.882 ± 0.075
3.322LeuGln: 3.322 ± 0.074
3.524LeuArg: 3.524 ± 0.068
7.163LeuSer: 7.163 ± 0.109
6.468LeuThr: 6.468 ± 0.089
6.889LeuVal: 6.889 ± 0.113
0.778LeuTrp: 0.778 ± 0.034
3.094LeuTyr: 3.094 ± 0.071
0.0LeuXaa: 0.0 ± 0.0
Met
1.98MetAla: 1.98 ± 0.05
0.125MetCys: 0.125 ± 0.013
1.37MetAsp: 1.37 ± 0.046
1.58MetGlu: 1.58 ± 0.042
0.941MetPhe: 0.941 ± 0.036
1.662MetGly: 1.662 ± 0.054
0.42MetHis: 0.42 ± 0.026
2.115MetIle: 2.115 ± 0.057
1.832MetLys: 1.832 ± 0.047
2.442MetLeu: 2.442 ± 0.058
0.814MetMet: 0.814 ± 0.034
1.47MetAsn: 1.47 ± 0.044
0.982MetPro: 0.982 ± 0.037
1.005MetGln: 1.005 ± 0.041
1.13MetArg: 1.13 ± 0.04
1.842MetSer: 1.842 ± 0.053
1.877MetThr: 1.877 ± 0.054
1.724MetVal: 1.724 ± 0.05
0.148MetTrp: 0.148 ± 0.013
0.72MetTyr: 0.72 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
3.128AsnAla: 3.128 ± 0.069
0.241AsnCys: 0.241 ± 0.021
2.541AsnAsp: 2.541 ± 0.063
3.592AsnGlu: 3.592 ± 0.097
2.155AsnPhe: 2.155 ± 0.056
3.173AsnGly: 3.173 ± 0.077
1.104AsnHis: 1.104 ± 0.042
3.625AsnIle: 3.625 ± 0.078
2.555AsnLys: 2.555 ± 0.066
4.579AsnLeu: 4.579 ± 0.088
1.176AsnMet: 1.176 ± 0.036
2.37AsnAsn: 2.37 ± 0.074
2.118AsnPro: 2.118 ± 0.051
2.563AsnGln: 2.563 ± 0.072
2.134AsnArg: 2.134 ± 0.06
2.691AsnSer: 2.691 ± 0.07
2.363AsnThr: 2.363 ± 0.059
3.103AsnVal: 3.103 ± 0.067
0.597AsnTrp: 0.597 ± 0.029
2.123AsnTyr: 2.123 ± 0.065
0.0AsnXaa: 0.0 ± 0.0
Pro
2.492ProAla: 2.492 ± 0.063
0.128ProCys: 0.128 ± 0.012
1.974ProAsp: 1.974 ± 0.052
3.178ProGlu: 3.178 ± 0.087
1.626ProPhe: 1.626 ± 0.048
2.044ProGly: 2.044 ± 0.06
0.734ProHis: 0.734 ± 0.031
2.647ProIle: 2.647 ± 0.061
1.683ProLys: 1.683 ± 0.049
3.237ProLeu: 3.237 ± 0.072
0.83ProMet: 0.83 ± 0.035
1.849ProAsn: 1.849 ± 0.052
0.656ProPro: 0.656 ± 0.033
1.31ProGln: 1.31 ± 0.04
1.025ProArg: 1.025 ± 0.04
2.122ProSer: 2.122 ± 0.062
2.293ProThr: 2.293 ± 0.071
2.637ProVal: 2.637 ± 0.065
0.288ProTrp: 0.288 ± 0.021
1.285ProTyr: 1.285 ± 0.046
0.0ProXaa: 0.0 ± 0.0
Gln
4.118GlnAla: 4.118 ± 0.085
0.135GlnCys: 0.135 ± 0.014
1.995GlnAsp: 1.995 ± 0.059
2.972GlnGlu: 2.972 ± 0.083
1.806GlnPhe: 1.806 ± 0.058
2.202GlnGly: 2.202 ± 0.054
0.929GlnHis: 0.929 ± 0.036
3.102GlnIle: 3.102 ± 0.071
2.126GlnLys: 2.126 ± 0.061
5.137GlnLeu: 5.137 ± 0.096
1.172GlnMet: 1.172 ± 0.039
1.88GlnAsn: 1.88 ± 0.056
1.378GlnPro: 1.378 ± 0.048
2.2GlnGln: 2.2 ± 0.081
1.782GlnArg: 1.782 ± 0.051
2.317GlnSer: 2.317 ± 0.061
2.661GlnThr: 2.661 ± 0.065
3.073GlnVal: 3.073 ± 0.063
0.429GlnTrp: 0.429 ± 0.024
1.552GlnTyr: 1.552 ± 0.054
0.0GlnXaa: 0.0 ± 0.0
Arg
2.441ArgAla: 2.441 ± 0.067
0.184ArgCys: 0.184 ± 0.016
2.06ArgAsp: 2.06 ± 0.06
3.023ArgGlu: 3.023 ± 0.072
1.842ArgPhe: 1.842 ± 0.05
2.099ArgGly: 2.099 ± 0.06
0.877ArgHis: 0.877 ± 0.037
3.176ArgIle: 3.176 ± 0.076
2.407ArgLys: 2.407 ± 0.078
4.347ArgLeu: 4.347 ± 0.112
1.098ArgMet: 1.098 ± 0.043
1.866ArgAsn: 1.866 ± 0.045
1.364ArgPro: 1.364 ± 0.053
2.055ArgGln: 2.055 ± 0.056
1.856ArgArg: 1.856 ± 0.051
2.035ArgSer: 2.035 ± 0.051
2.072ArgThr: 2.072 ± 0.051
2.673ArgVal: 2.673 ± 0.066
0.312ArgTrp: 0.312 ± 0.021
1.694ArgTyr: 1.694 ± 0.056
0.0ArgXaa: 0.0 ± 0.0
Ser
4.257SerAla: 4.257 ± 0.089
0.224SerCys: 0.224 ± 0.02
3.397SerAsp: 3.397 ± 0.082
4.643SerGlu: 4.643 ± 0.102
3.029SerPhe: 3.029 ± 0.076
4.308SerGly: 4.308 ± 0.087
1.291SerHis: 1.291 ± 0.048
4.749SerIle: 4.749 ± 0.083
3.07SerLys: 3.07 ± 0.07
6.248SerLeu: 6.248 ± 0.097
1.486SerMet: 1.486 ± 0.042
2.821SerAsn: 2.821 ± 0.075
2.079SerPro: 2.079 ± 0.059
2.776SerGln: 2.776 ± 0.07
2.358SerArg: 2.358 ± 0.057
3.873SerSer: 3.873 ± 0.095
3.373SerThr: 3.373 ± 0.074
4.341SerVal: 4.341 ± 0.087
0.613SerTrp: 0.613 ± 0.029
2.255SerTyr: 2.255 ± 0.063
0.0SerXaa: 0.0 ± 0.0
Thr
4.199ThrAla: 4.199 ± 0.087
0.246ThrCys: 0.246 ± 0.018
3.22ThrAsp: 3.22 ± 0.082
4.276ThrGlu: 4.276 ± 0.096
2.425ThrPhe: 2.425 ± 0.063
3.987ThrGly: 3.987 ± 0.086
1.222ThrHis: 1.222 ± 0.047
4.895ThrIle: 4.895 ± 0.094
2.835ThrLys: 2.835 ± 0.07
5.818ThrLeu: 5.818 ± 0.101
1.3ThrMet: 1.3 ± 0.041
2.591ThrAsn: 2.591 ± 0.059
2.457ThrPro: 2.457 ± 0.071
2.324ThrGln: 2.324 ± 0.059
2.058ThrArg: 2.058 ± 0.06
3.599ThrSer: 3.599 ± 0.075
3.419ThrThr: 3.419 ± 0.091
4.429ThrVal: 4.429 ± 0.086
0.497ThrTrp: 0.497 ± 0.038
2.202ThrTyr: 2.202 ± 0.064
0.0ThrXaa: 0.0 ± 0.0
Val
5.652ValAla: 5.652 ± 0.1
0.384ValCys: 0.384 ± 0.021
4.225ValAsp: 4.225 ± 0.073
5.559ValGlu: 5.559 ± 0.106
3.046ValPhe: 3.046 ± 0.07
4.667ValGly: 4.667 ± 0.101
1.201ValHis: 1.201 ± 0.042
5.832ValIle: 5.832 ± 0.096
3.92ValLys: 3.92 ± 0.077
6.648ValLeu: 6.648 ± 0.101
1.886ValMet: 1.886 ± 0.056
3.354ValAsn: 3.354 ± 0.074
2.637ValPro: 2.637 ± 0.062
2.364ValGln: 2.364 ± 0.059
2.428ValArg: 2.428 ± 0.062
4.695ValSer: 4.695 ± 0.088
4.564ValThr: 4.564 ± 0.108
5.274ValVal: 5.274 ± 0.092
0.542ValTrp: 0.542 ± 0.031
2.418ValTyr: 2.418 ± 0.056
0.0ValXaa: 0.0 ± 0.0
Trp
0.567TrpAla: 0.567 ± 0.031
0.042TrpCys: 0.042 ± 0.007
0.507TrpAsp: 0.507 ± 0.029
0.55TrpGlu: 0.55 ± 0.03
0.451TrpPhe: 0.451 ± 0.03
0.567TrpGly: 0.567 ± 0.028
0.212TrpHis: 0.212 ± 0.019
0.597TrpIle: 0.597 ± 0.029
0.425TrpLys: 0.425 ± 0.025
1.281TrpLeu: 1.281 ± 0.048
0.251TrpMet: 0.251 ± 0.019
0.465TrpAsn: 0.465 ± 0.032
0.256TrpPro: 0.256 ± 0.019
0.56TrpGln: 0.56 ± 0.028
0.401TrpArg: 0.401 ± 0.027
0.553TrpSer: 0.553 ± 0.028
0.473TrpThr: 0.473 ± 0.039
0.571TrpVal: 0.571 ± 0.029
0.104TrpTrp: 0.104 ± 0.013
0.304TrpTyr: 0.304 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.56TyrAla: 2.56 ± 0.054
0.234TyrCys: 0.234 ± 0.018
2.311TyrAsp: 2.311 ± 0.06
2.452TyrGlu: 2.452 ± 0.058
2.119TyrPhe: 2.119 ± 0.056
2.47TyrGly: 2.47 ± 0.062
0.948TyrHis: 0.948 ± 0.04
2.503TyrIle: 2.503 ± 0.06
1.541TyrLys: 1.541 ± 0.042
4.092TyrLeu: 4.092 ± 0.068
0.759TyrMet: 0.759 ± 0.031
1.605TyrAsn: 1.605 ± 0.058
1.499TyrPro: 1.499 ± 0.049
2.141TyrGln: 2.141 ± 0.057
1.758TyrArg: 1.758 ± 0.053
2.386TyrSer: 2.386 ± 0.066
2.009TyrThr: 2.009 ± 0.064
2.367TyrVal: 2.367 ± 0.061
0.422TyrTrp: 0.422 ± 0.023
1.765TyrTyr: 1.765 ± 0.056
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2258 proteins (718277 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski