Amino acid dipepetide frequency for Daeseongdong virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.704AlaAla: 3.704 ± 0.606
0.673AlaCys: 0.673 ± 1.082
2.02AlaAsp: 2.02 ± 0.931
3.704AlaGlu: 3.704 ± 0.406
2.694AlaPhe: 2.694 ± 0.844
2.02AlaGly: 2.02 ± 1.958
1.01AlaHis: 1.01 ± 0.508
3.704AlaIle: 3.704 ± 3.614
3.03AlaLys: 3.03 ± 0.459
9.428AlaLeu: 9.428 ± 5.012
1.01AlaMet: 1.01 ± 0.508
2.02AlaAsn: 2.02 ± 1.958
3.367AlaPro: 3.367 ± 2.847
1.347AlaGln: 1.347 ± 0.896
2.357AlaArg: 2.357 ± 1.184
4.714AlaSer: 4.714 ± 1.286
3.704AlaThr: 3.704 ± 1.289
6.061AlaVal: 6.061 ± 0.58
0.337AlaTrp: 0.337 ± 0.169
2.02AlaTyr: 2.02 ± 0.521
0.0AlaXaa: 0.0 ± 0.0
Cys
0.673CysAla: 0.673 ± 0.338
0.0CysCys: 0.0 ± 0.0
1.01CysAsp: 1.01 ± 0.508
1.01CysGlu: 1.01 ± 0.466
1.01CysPhe: 1.01 ± 0.466
0.673CysGly: 0.673 ± 0.338
0.673CysHis: 0.673 ± 0.559
0.337CysIle: 0.337 ± 0.169
1.347CysLys: 1.347 ± 0.677
2.694CysLeu: 2.694 ± 0.844
0.673CysMet: 0.673 ± 0.338
0.673CysAsn: 0.673 ± 0.338
1.347CysPro: 1.347 ± 0.677
1.01CysGln: 1.01 ± 0.508
1.347CysArg: 1.347 ± 0.422
3.03CysSer: 3.03 ± 0.849
1.01CysThr: 1.01 ± 0.508
1.684CysVal: 1.684 ± 0.84
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.04AspAla: 4.04 ± 2.03
2.357AspCys: 2.357 ± 0.636
2.357AspAsp: 2.357 ± 1.184
2.694AspGlu: 2.694 ± 1.354
3.03AspPhe: 3.03 ± 0.944
3.367AspGly: 3.367 ± 0.886
1.347AspHis: 1.347 ± 0.677
5.051AspIle: 5.051 ± 0.778
2.694AspLys: 2.694 ± 0.565
5.051AspLeu: 5.051 ± 0.872
2.357AspMet: 2.357 ± 1.184
1.684AspAsn: 1.684 ± 0.443
3.704AspPro: 3.704 ± 1.228
1.684AspGln: 1.684 ± 0.443
3.03AspArg: 3.03 ± 0.849
5.724AspSer: 5.724 ± 0.538
4.04AspThr: 4.04 ± 2.03
6.061AspVal: 6.061 ± 1.564
0.337AspTrp: 0.337 ± 0.683
1.347AspTyr: 1.347 ± 0.677
0.0AspXaa: 0.0 ± 0.0
Glu
2.02GluAla: 2.02 ± 0.815
3.367GluCys: 3.367 ± 1.071
2.694GluAsp: 2.694 ± 0.771
3.367GluGlu: 3.367 ± 1.692
4.377GluPhe: 4.377 ± 2.492
1.347GluGly: 1.347 ± 0.677
1.01GluHis: 1.01 ± 0.508
4.377GluIle: 4.377 ± 1.265
4.377GluLys: 4.377 ± 0.268
6.734GluLeu: 6.734 ± 1.785
0.673GluMet: 0.673 ± 0.338
2.02GluAsn: 2.02 ± 1.015
1.684GluPro: 1.684 ± 0.846
1.347GluGln: 1.347 ± 0.677
2.02GluArg: 2.02 ± 1.015
2.357GluSer: 2.357 ± 1.184
3.367GluThr: 3.367 ± 1.333
3.704GluVal: 3.704 ± 1.861
0.673GluTrp: 0.673 ± 0.559
2.694GluTyr: 2.694 ± 0.565
0.0GluXaa: 0.0 ± 0.0
Phe
3.367PheAla: 3.367 ± 0.775
1.684PheCys: 1.684 ± 0.443
5.051PheAsp: 5.051 ± 0.077
4.04PheGlu: 4.04 ± 1.863
5.387PhePhe: 5.387 ± 1.46
3.704PheGly: 3.704 ± 0.406
1.684PheHis: 1.684 ± 0.846
3.367PheIle: 3.367 ± 0.399
2.02PheLys: 2.02 ± 1.015
5.051PheLeu: 5.051 ± 2.395
1.347PheMet: 1.347 ± 0.627
3.03PheAsn: 3.03 ± 1.523
1.347PhePro: 1.347 ± 0.422
1.347PheGln: 1.347 ± 0.677
4.04PheArg: 4.04 ± 0.477
4.377PheSer: 4.377 ± 1.072
6.397PheThr: 6.397 ± 0.45
4.714PheVal: 4.714 ± 1.745
1.01PheTrp: 1.01 ± 0.979
1.347PheTyr: 1.347 ± 1.119
0.0PheXaa: 0.0 ± 0.0
Gly
2.357GlyAla: 2.357 ± 0.872
1.01GlyCys: 1.01 ± 0.508
7.407GlyAsp: 7.407 ± 2.039
2.694GlyGlu: 2.694 ± 0.844
1.684GlyPhe: 1.684 ± 0.84
3.367GlyGly: 3.367 ± 1.646
1.347GlyHis: 1.347 ± 0.896
2.694GlyIle: 2.694 ± 0.771
2.02GlyLys: 2.02 ± 0.815
2.694GlyLeu: 2.694 ± 1.893
1.684GlyMet: 1.684 ± 0.604
2.02GlyAsn: 2.02 ± 0.931
1.01GlyPro: 1.01 ± 0.466
1.684GlyGln: 1.684 ± 0.443
1.684GlyArg: 1.684 ± 1.015
1.347GlySer: 1.347 ± 0.422
3.03GlyThr: 3.03 ± 1.728
5.051GlyVal: 5.051 ± 0.077
0.0GlyTrp: 0.0 ± 0.0
1.684GlyTyr: 1.684 ± 0.846
0.0GlyXaa: 0.0 ± 0.0
His
1.01HisAla: 1.01 ± 0.466
0.673HisCys: 0.673 ± 0.338
1.347HisAsp: 1.347 ± 0.677
1.01HisGlu: 1.01 ± 0.508
1.347HisPhe: 1.347 ± 0.422
0.673HisGly: 0.673 ± 0.559
0.0HisHis: 0.0 ± 0.0
1.347HisIle: 1.347 ± 0.896
0.337HisLys: 0.337 ± 0.169
2.02HisLeu: 2.02 ± 0.521
0.673HisMet: 0.673 ± 0.338
1.684HisAsn: 1.684 ± 0.846
2.02HisPro: 2.02 ± 0.521
0.673HisGln: 0.673 ± 1.082
1.684HisArg: 1.684 ± 0.846
1.347HisSer: 1.347 ± 1.119
1.684HisThr: 1.684 ± 0.84
3.704HisVal: 3.704 ± 0.406
0.337HisTrp: 0.337 ± 0.169
0.673HisTyr: 0.673 ± 0.338
0.0HisXaa: 0.0 ± 0.0
Ile
4.714IleAla: 4.714 ± 2.567
1.01IleCys: 1.01 ± 0.508
6.061IleAsp: 6.061 ± 1.697
2.357IleGlu: 2.357 ± 1.184
3.03IlePhe: 3.03 ± 0.459
2.02IleGly: 2.02 ± 0.841
0.337IleHis: 0.337 ± 0.169
1.01IleIle: 1.01 ± 0.508
3.367IleLys: 3.367 ± 1.071
4.714IleLeu: 4.714 ± 1.744
0.673IleMet: 0.673 ± 1.029
1.684IleAsn: 1.684 ± 0.846
3.03IlePro: 3.03 ± 0.918
1.347IleGln: 1.347 ± 1.152
3.704IleArg: 3.704 ± 1.148
6.061IleSer: 6.061 ± 0.58
3.03IleThr: 3.03 ± 1.766
3.704IleVal: 3.704 ± 1.289
0.0IleTrp: 0.0 ± 0.0
2.357IleTyr: 2.357 ± 1.572
0.0IleXaa: 0.0 ± 0.0
Lys
1.684LysAla: 1.684 ± 0.443
0.673LysCys: 0.673 ± 0.559
3.367LysAsp: 3.367 ± 0.886
2.357LysGlu: 2.357 ± 0.825
5.387LysPhe: 5.387 ± 0.647
2.02LysGly: 2.02 ± 0.521
2.02LysHis: 2.02 ± 0.521
3.367LysIle: 3.367 ± 0.775
2.357LysLys: 2.357 ± 0.825
5.724LysLeu: 5.724 ± 2.21
2.02LysMet: 2.02 ± 1.015
2.694LysAsn: 2.694 ± 1.354
4.04LysPro: 4.04 ± 1.438
1.684LysGln: 1.684 ± 0.846
3.03LysArg: 3.03 ± 1.523
5.387LysSer: 5.387 ± 3.364
2.694LysThr: 2.694 ± 1.354
3.367LysVal: 3.367 ± 0.775
1.01LysTrp: 1.01 ± 1.312
1.01LysTyr: 1.01 ± 0.508
0.0LysXaa: 0.0 ± 0.0
Leu
7.744LeuAla: 7.744 ± 5.572
2.02LeuCys: 2.02 ± 0.931
3.704LeuAsp: 3.704 ± 1.148
7.071LeuGlu: 7.071 ± 2.298
4.04LeuPhe: 4.04 ± 1.863
4.04LeuGly: 4.04 ± 2.903
3.704LeuHis: 3.704 ± 0.406
5.724LeuIle: 5.724 ± 1.471
4.714LeuLys: 4.714 ± 1.714
6.734LeuLeu: 6.734 ± 2.231
1.684LeuMet: 1.684 ± 0.846
4.714LeuAsn: 4.714 ± 1.649
4.04LeuPro: 4.04 ± 1.043
3.03LeuGln: 3.03 ± 0.944
3.367LeuArg: 3.367 ± 1.692
6.061LeuSer: 6.061 ± 0.58
5.724LeuThr: 5.724 ± 0.538
6.397LeuVal: 6.397 ± 6.735
0.673LeuTrp: 0.673 ± 1.082
3.367LeuTyr: 3.367 ± 0.399
0.0LeuXaa: 0.0 ± 0.0
Met
1.01MetAla: 1.01 ± 0.508
0.673MetCys: 0.673 ± 0.338
0.337MetAsp: 0.337 ± 0.169
0.337MetGlu: 0.337 ± 0.683
1.01MetPhe: 1.01 ± 0.508
1.01MetGly: 1.01 ± 0.508
0.337MetHis: 0.337 ± 0.169
1.684MetIle: 1.684 ± 0.846
2.357MetLys: 2.357 ± 1.282
2.02MetLeu: 2.02 ± 0.815
0.0MetMet: 0.0 ± 0.0
1.347MetAsn: 1.347 ± 1.119
1.01MetPro: 1.01 ± 0.508
0.673MetGln: 0.673 ± 0.338
2.694MetArg: 2.694 ± 0.771
3.03MetSer: 3.03 ± 0.94
0.673MetThr: 0.673 ± 0.338
1.347MetVal: 1.347 ± 1.119
0.0MetTrp: 0.0 ± 0.0
0.673MetTyr: 0.673 ± 0.338
0.0MetXaa: 0.0 ± 0.0
Asn
2.02AsnAla: 2.02 ± 0.815
1.01AsnCys: 1.01 ± 0.466
2.357AsnAsp: 2.357 ± 0.696
1.347AsnGlu: 1.347 ± 0.677
4.04AsnPhe: 4.04 ± 1.043
3.367AsnGly: 3.367 ± 1.071
0.673AsnHis: 0.673 ± 0.338
1.684AsnIle: 1.684 ± 0.443
3.03AsnLys: 3.03 ± 1.766
3.704AsnLeu: 3.704 ± 1.228
1.01AsnMet: 1.01 ± 0.508
2.694AsnAsn: 2.694 ± 0.565
1.684AsnPro: 1.684 ± 0.846
1.01AsnGln: 1.01 ± 0.979
3.704AsnArg: 3.704 ± 1.148
5.724AsnSer: 5.724 ± 2.458
3.03AsnThr: 3.03 ± 0.849
4.377AsnVal: 4.377 ± 1.265
0.337AsnTrp: 0.337 ± 0.683
2.694AsnTyr: 2.694 ± 1.354
0.0AsnXaa: 0.0 ± 0.0
Pro
3.704ProAla: 3.704 ± 1.646
0.337ProCys: 0.337 ± 0.169
2.02ProAsp: 2.02 ± 0.815
1.684ProGlu: 1.684 ± 0.443
2.694ProPhe: 2.694 ± 0.771
4.377ProGly: 4.377 ± 0.268
0.673ProHis: 0.673 ± 0.338
2.694ProIle: 2.694 ± 0.844
3.704ProLys: 3.704 ± 1.387
3.03ProLeu: 3.03 ± 0.459
1.01ProMet: 1.01 ± 0.508
2.694ProAsn: 2.694 ± 0.844
0.673ProPro: 0.673 ± 0.559
1.01ProGln: 1.01 ± 0.979
1.684ProArg: 1.684 ± 2.057
4.714ProSer: 4.714 ± 1.745
2.357ProThr: 2.357 ± 0.696
5.724ProVal: 5.724 ± 1.015
0.337ProTrp: 0.337 ± 0.169
2.357ProTyr: 2.357 ± 2.353
0.0ProXaa: 0.0 ± 0.0
Gln
1.347GlnAla: 1.347 ± 2.165
0.0GlnCys: 0.0 ± 0.0
1.347GlnAsp: 1.347 ± 0.677
2.694GlnGlu: 2.694 ± 0.844
0.673GlnPhe: 0.673 ± 0.338
0.673GlnGly: 0.673 ± 0.338
0.673GlnHis: 0.673 ± 0.338
1.01GlnIle: 1.01 ± 0.508
2.694GlnLys: 2.694 ± 0.868
2.02GlnLeu: 2.02 ± 0.521
1.01GlnMet: 1.01 ± 1.312
2.02GlnAsn: 2.02 ± 1.958
1.01GlnPro: 1.01 ± 0.508
0.673GlnGln: 0.673 ± 0.338
2.357GlnArg: 2.357 ± 1.184
3.03GlnSer: 3.03 ± 0.849
1.01GlnThr: 1.01 ± 0.508
1.347GlnVal: 1.347 ± 0.896
0.0GlnTrp: 0.0 ± 0.0
1.684GlnTyr: 1.684 ± 0.443
0.0GlnXaa: 0.0 ± 0.0
Arg
3.367ArgAla: 3.367 ± 1.679
1.01ArgCys: 1.01 ± 0.466
4.04ArgAsp: 4.04 ± 1.043
4.04ArgGlu: 4.04 ± 1.043
3.03ArgPhe: 3.03 ± 0.918
1.347ArgGly: 1.347 ± 0.677
1.01ArgHis: 1.01 ± 0.508
3.367ArgIle: 3.367 ± 1.071
2.694ArgLys: 2.694 ± 1.354
6.061ArgLeu: 6.061 ± 1.229
1.347ArgMet: 1.347 ± 0.422
5.051ArgAsn: 5.051 ± 0.872
2.357ArgPro: 2.357 ± 1.282
1.684ArgGln: 1.684 ± 1.621
2.694ArgArg: 2.694 ± 0.868
4.377ArgSer: 4.377 ± 2.199
4.714ArgThr: 4.714 ± 1.714
3.704ArgVal: 3.704 ± 1.646
0.337ArgTrp: 0.337 ± 0.169
1.347ArgTyr: 1.347 ± 0.422
0.0ArgXaa: 0.0 ± 0.0
Ser
5.724SerAla: 5.724 ± 1.398
0.337SerCys: 0.337 ± 0.169
5.724SerAsp: 5.724 ± 0.538
4.04SerGlu: 4.04 ± 1.043
5.724SerPhe: 5.724 ± 1.687
6.397SerGly: 6.397 ± 1.273
2.02SerHis: 2.02 ± 1.015
2.694SerIle: 2.694 ± 1.113
4.377SerLys: 4.377 ± 1.797
5.387SerLeu: 5.387 ± 1.026
2.02SerMet: 2.02 ± 0.521
3.367SerAsn: 3.367 ± 0.886
4.377SerPro: 4.377 ± 3.473
2.357SerGln: 2.357 ± 1.184
5.051SerArg: 5.051 ± 1.257
3.03SerSer: 3.03 ± 2.938
7.071SerThr: 7.071 ± 1.417
6.061SerVal: 6.061 ± 1.235
0.673SerTrp: 0.673 ± 0.338
4.377SerTyr: 4.377 ± 1.265
0.0SerXaa: 0.0 ± 0.0
Thr
3.704ThrAla: 3.704 ± 1.228
1.347ThrCys: 1.347 ± 0.677
1.347ThrAsp: 1.347 ± 0.677
4.04ThrGlu: 4.04 ± 1.388
6.734ThrPhe: 6.734 ± 1.671
0.0ThrGly: 0.0 ± 0.0
1.684ThrHis: 1.684 ± 0.994
4.377ThrIle: 4.377 ± 1.551
4.714ThrLys: 4.714 ± 1.548
5.387ThrLeu: 5.387 ± 1.13
0.337ThrMet: 0.337 ± 0.169
2.694ThrAsn: 2.694 ± 1.113
4.04ThrPro: 4.04 ± 2.728
1.684ThrGln: 1.684 ± 0.846
3.367ThrArg: 3.367 ± 1.548
5.387ThrSer: 5.387 ± 1.687
3.367ThrThr: 3.367 ± 0.775
4.714ThrVal: 4.714 ± 1.714
0.0ThrTrp: 0.0 ± 0.0
2.694ThrTyr: 2.694 ± 1.874
0.0ThrXaa: 0.0 ± 0.0
Val
5.051ValAla: 5.051 ± 3.659
1.01ValCys: 1.01 ± 0.508
5.051ValAsp: 5.051 ± 1.879
3.367ValGlu: 3.367 ± 1.071
4.714ValPhe: 4.714 ± 2.514
4.04ValGly: 4.04 ± 1.043
2.02ValHis: 2.02 ± 1.451
5.051ValIle: 5.051 ± 2.422
4.04ValLys: 4.04 ± 1.266
6.061ValLeu: 6.061 ± 3.842
1.347ValMet: 1.347 ± 0.896
5.387ValAsn: 5.387 ± 1.026
6.061ValPro: 6.061 ± 2.826
1.684ValGln: 1.684 ± 0.846
6.734ValArg: 6.734 ± 0.918
7.407ValSer: 7.407 ± 1.512
3.03ValThr: 3.03 ± 0.944
5.724ValVal: 5.724 ± 2.249
0.0ValTrp: 0.0 ± 0.0
3.367ValTyr: 3.367 ± 0.775
0.0ValXaa: 0.0 ± 0.0
Trp
0.337TrpAla: 0.337 ± 0.169
0.0TrpCys: 0.0 ± 0.0
0.673TrpAsp: 0.673 ± 0.338
0.337TrpGlu: 0.337 ± 0.169
1.01TrpPhe: 1.01 ± 1.237
0.0TrpGly: 0.0 ± 0.0
0.337TrpHis: 0.337 ± 0.169
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.673TrpLeu: 0.673 ± 0.559
0.0TrpMet: 0.0 ± 0.0
0.337TrpAsn: 0.337 ± 0.169
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.337TrpArg: 0.337 ± 0.169
0.0TrpSer: 0.0 ± 0.0
0.337TrpThr: 0.337 ± 0.169
1.01TrpVal: 1.01 ± 3.602
0.0TrpTrp: 0.0 ± 0.0
0.673TrpTyr: 0.673 ± 0.559
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.347TyrAla: 1.347 ± 0.896
1.01TyrCys: 1.01 ± 0.508
4.04TyrAsp: 4.04 ± 1.388
2.02TyrGlu: 2.02 ± 0.815
2.694TyrPhe: 2.694 ± 1.792
2.02TyrGly: 2.02 ± 0.931
1.684TyrHis: 1.684 ± 1.015
1.01TyrIle: 1.01 ± 0.466
2.02TyrLys: 2.02 ± 0.521
3.367TyrLeu: 3.367 ± 2.031
1.01TyrMet: 1.01 ± 2.049
1.684TyrAsn: 1.684 ± 0.443
0.673TyrPro: 0.673 ± 0.559
1.347TyrGln: 1.347 ± 0.677
2.694TyrArg: 2.694 ± 0.844
3.704TyrSer: 3.704 ± 1.941
1.347TyrThr: 1.347 ± 0.422
2.694TyrVal: 2.694 ± 1.354
0.0TyrTrp: 0.0 ± 0.0
1.01TyrTyr: 1.01 ± 0.508
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2971 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski