Amino acid dipepetide frequency for Salmonella phage FSL SP-076

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.024AlaAla: 9.024 ± 1.067
0.427AlaCys: 0.427 ± 0.181
5.034AlaAsp: 5.034 ± 0.608
4.512AlaGlu: 4.512 ± 0.633
2.897AlaPhe: 2.897 ± 0.449
6.364AlaGly: 6.364 ± 0.653
1.187AlaHis: 1.187 ± 0.204
5.034AlaIle: 5.034 ± 0.632
5.652AlaLys: 5.652 ± 0.481
7.266AlaLeu: 7.266 ± 0.609
1.995AlaMet: 1.995 ± 0.294
4.702AlaAsn: 4.702 ± 0.479
2.85AlaPro: 2.85 ± 0.392
4.417AlaGln: 4.417 ± 0.664
3.514AlaArg: 3.514 ± 0.563
4.417AlaSer: 4.417 ± 0.474
4.512AlaThr: 4.512 ± 0.588
5.794AlaVal: 5.794 ± 0.659
0.522AlaTrp: 0.522 ± 0.156
2.897AlaTyr: 2.897 ± 0.398
0.0AlaXaa: 0.0 ± 0.0
Cys
0.522CysAla: 0.522 ± 0.209
0.19CysCys: 0.19 ± 0.096
0.475CysAsp: 0.475 ± 0.169
0.38CysGlu: 0.38 ± 0.131
0.237CysPhe: 0.237 ± 0.099
0.617CysGly: 0.617 ± 0.235
0.332CysHis: 0.332 ± 0.152
0.997CysIle: 0.997 ± 0.271
0.522CysLys: 0.522 ± 0.202
0.902CysLeu: 0.902 ± 0.277
0.285CysMet: 0.285 ± 0.13
0.427CysAsn: 0.427 ± 0.149
0.427CysPro: 0.427 ± 0.157
0.38CysGln: 0.38 ± 0.21
0.285CysArg: 0.285 ± 0.13
0.807CysSer: 0.807 ± 0.334
0.665CysThr: 0.665 ± 0.238
0.475CysVal: 0.475 ± 0.153
0.047CysTrp: 0.047 ± 0.053
0.095CysTyr: 0.095 ± 0.068
0.0CysXaa: 0.0 ± 0.0
Asp
5.224AspAla: 5.224 ± 0.575
0.712AspCys: 0.712 ± 0.256
2.945AspAsp: 2.945 ± 0.537
4.084AspGlu: 4.084 ± 0.477
2.09AspPhe: 2.09 ± 0.264
5.462AspGly: 5.462 ± 0.896
1.14AspHis: 1.14 ± 0.206
4.417AspIle: 4.417 ± 0.536
4.084AspLys: 4.084 ± 0.538
5.984AspLeu: 5.984 ± 0.364
1.615AspMet: 1.615 ± 0.226
2.565AspAsn: 2.565 ± 0.329
2.422AspPro: 2.422 ± 0.317
1.282AspGln: 1.282 ± 0.274
2.137AspArg: 2.137 ± 0.271
3.989AspSer: 3.989 ± 0.415
3.657AspThr: 3.657 ± 0.361
4.179AspVal: 4.179 ± 0.45
0.855AspTrp: 0.855 ± 0.211
2.85AspTyr: 2.85 ± 0.558
0.0AspXaa: 0.0 ± 0.0
Glu
5.557GluAla: 5.557 ± 0.681
0.807GluCys: 0.807 ± 0.275
2.517GluAsp: 2.517 ± 0.416
4.702GluGlu: 4.702 ± 0.614
2.707GluPhe: 2.707 ± 0.385
3.562GluGly: 3.562 ± 0.427
0.855GluHis: 0.855 ± 0.239
3.894GluIle: 3.894 ± 0.427
4.227GluLys: 4.227 ± 0.586
7.266GluLeu: 7.266 ± 0.674
2.327GluMet: 2.327 ± 0.319
2.517GluAsn: 2.517 ± 0.388
2.755GluPro: 2.755 ± 0.418
3.704GluGln: 3.704 ± 0.548
2.327GluArg: 2.327 ± 0.355
3.372GluSer: 3.372 ± 0.475
4.132GluThr: 4.132 ± 0.626
4.417GluVal: 4.417 ± 0.441
0.712GluTrp: 0.712 ± 0.214
2.09GluTyr: 2.09 ± 0.221
0.0GluXaa: 0.0 ± 0.0
Phe
2.802PheAla: 2.802 ± 0.42
0.427PheCys: 0.427 ± 0.171
2.375PheAsp: 2.375 ± 0.287
2.422PheGlu: 2.422 ± 0.357
1.377PhePhe: 1.377 ± 0.324
3.04PheGly: 3.04 ± 0.355
0.332PheHis: 0.332 ± 0.119
2.66PheIle: 2.66 ± 0.363
2.232PheLys: 2.232 ± 0.278
2.707PheLeu: 2.707 ± 0.337
0.855PheMet: 0.855 ± 0.209
2.66PheAsn: 2.66 ± 0.375
1.33PhePro: 1.33 ± 0.306
1.092PheGln: 1.092 ± 0.222
1.71PheArg: 1.71 ± 0.292
1.71PheSer: 1.71 ± 0.303
2.517PheThr: 2.517 ± 0.342
2.375PheVal: 2.375 ± 0.35
0.522PheTrp: 0.522 ± 0.167
1.567PheTyr: 1.567 ± 0.297
0.0PheXaa: 0.0 ± 0.0
Gly
5.177GlyAla: 5.177 ± 0.584
0.475GlyCys: 0.475 ± 0.17
3.942GlyAsp: 3.942 ± 0.672
3.894GlyGlu: 3.894 ± 0.492
2.802GlyPhe: 2.802 ± 0.31
3.514GlyGly: 3.514 ± 0.672
0.997GlyHis: 0.997 ± 0.24
5.272GlyIle: 5.272 ± 0.464
5.177GlyLys: 5.177 ± 0.61
6.222GlyLeu: 6.222 ± 0.604
1.9GlyMet: 1.9 ± 0.335
3.847GlyAsn: 3.847 ± 0.333
0.95GlyPro: 0.95 ± 0.264
2.897GlyGln: 2.897 ± 0.48
3.04GlyArg: 3.04 ± 0.395
5.224GlySer: 5.224 ± 0.827
4.369GlyThr: 4.369 ± 0.572
4.322GlyVal: 4.322 ± 0.562
0.902GlyTrp: 0.902 ± 0.237
2.897GlyTyr: 2.897 ± 0.302
0.0GlyXaa: 0.0 ± 0.0
His
0.95HisAla: 0.95 ± 0.207
0.332HisCys: 0.332 ± 0.144
0.95HisAsp: 0.95 ± 0.314
1.235HisGlu: 1.235 ± 0.261
0.57HisPhe: 0.57 ± 0.177
0.807HisGly: 0.807 ± 0.202
0.427HisHis: 0.427 ± 0.143
0.855HisIle: 0.855 ± 0.156
0.855HisLys: 0.855 ± 0.253
1.615HisLeu: 1.615 ± 0.231
0.522HisMet: 0.522 ± 0.159
0.76HisAsn: 0.76 ± 0.228
1.045HisPro: 1.045 ± 0.174
0.76HisGln: 0.76 ± 0.171
0.522HisArg: 0.522 ± 0.19
0.997HisSer: 0.997 ± 0.201
0.855HisThr: 0.855 ± 0.187
1.282HisVal: 1.282 ± 0.251
0.142HisTrp: 0.142 ± 0.083
0.665HisTyr: 0.665 ± 0.184
0.0HisXaa: 0.0 ± 0.0
Ile
6.174IleAla: 6.174 ± 0.642
0.665IleCys: 0.665 ± 0.215
5.082IleAsp: 5.082 ± 0.487
4.274IleGlu: 4.274 ± 0.461
2.042IlePhe: 2.042 ± 0.305
4.179IleGly: 4.179 ± 0.554
1.567IleHis: 1.567 ± 0.374
3.657IleIle: 3.657 ± 0.526
4.559IleLys: 4.559 ± 0.465
3.894IleLeu: 3.894 ± 0.456
1.14IleMet: 1.14 ± 0.214
3.942IleAsn: 3.942 ± 0.58
2.897IlePro: 2.897 ± 0.38
2.945IleGln: 2.945 ± 0.405
3.419IleArg: 3.419 ± 0.49
4.037IleSer: 4.037 ± 0.372
4.037IleThr: 4.037 ± 0.415
4.037IleVal: 4.037 ± 0.572
0.807IleTrp: 0.807 ± 0.267
1.377IleTyr: 1.377 ± 0.266
0.0IleXaa: 0.0 ± 0.0
Lys
5.272LysAla: 5.272 ± 0.68
0.285LysCys: 0.285 ± 0.138
4.654LysAsp: 4.654 ± 0.67
4.417LysGlu: 4.417 ± 0.606
2.517LysPhe: 2.517 ± 0.526
3.467LysGly: 3.467 ± 0.46
1.33LysHis: 1.33 ± 0.317
3.467LysIle: 3.467 ± 0.481
2.897LysLys: 2.897 ± 0.504
6.079LysLeu: 6.079 ± 0.614
2.042LysMet: 2.042 ± 0.342
3.182LysAsn: 3.182 ± 0.363
2.755LysPro: 2.755 ± 0.376
3.134LysGln: 3.134 ± 0.369
2.85LysArg: 2.85 ± 0.375
3.752LysSer: 3.752 ± 0.445
3.229LysThr: 3.229 ± 0.426
4.274LysVal: 4.274 ± 0.477
0.38LysTrp: 0.38 ± 0.14
2.517LysTyr: 2.517 ± 0.394
0.0LysXaa: 0.0 ± 0.0
Leu
7.836LeuAla: 7.836 ± 0.566
0.855LeuCys: 0.855 ± 0.249
5.794LeuAsp: 5.794 ± 0.646
4.749LeuGlu: 4.749 ± 0.662
2.28LeuPhe: 2.28 ± 0.258
5.319LeuGly: 5.319 ± 0.466
1.33LeuHis: 1.33 ± 0.252
5.652LeuIle: 5.652 ± 0.596
4.892LeuLys: 4.892 ± 0.711
6.696LeuLeu: 6.696 ± 0.43
2.802LeuMet: 2.802 ± 0.348
5.842LeuAsn: 5.842 ± 0.48
4.464LeuPro: 4.464 ± 0.493
3.847LeuGln: 3.847 ± 0.42
4.559LeuArg: 4.559 ± 0.487
5.747LeuSer: 5.747 ± 0.484
5.177LeuThr: 5.177 ± 0.496
4.844LeuVal: 4.844 ± 0.555
0.855LeuTrp: 0.855 ± 0.269
2.232LeuTyr: 2.232 ± 0.325
0.0LeuXaa: 0.0 ± 0.0
Met
2.565MetAla: 2.565 ± 0.329
0.237MetCys: 0.237 ± 0.102
2.185MetAsp: 2.185 ± 0.273
1.377MetGlu: 1.377 ± 0.249
0.712MetPhe: 0.712 ± 0.169
1.71MetGly: 1.71 ± 0.278
0.38MetHis: 0.38 ± 0.137
1.425MetIle: 1.425 ± 0.295
1.52MetLys: 1.52 ± 0.226
2.802MetLeu: 2.802 ± 0.443
0.57MetMet: 0.57 ± 0.148
1.425MetAsn: 1.425 ± 0.248
1.092MetPro: 1.092 ± 0.252
1.567MetGln: 1.567 ± 0.32
0.902MetArg: 0.902 ± 0.224
2.137MetSer: 2.137 ± 0.294
1.757MetThr: 1.757 ± 0.313
1.615MetVal: 1.615 ± 0.3
0.237MetTrp: 0.237 ± 0.098
0.902MetTyr: 0.902 ± 0.222
0.0MetXaa: 0.0 ± 0.0
Asn
4.417AsnAla: 4.417 ± 0.61
0.475AsnCys: 0.475 ± 0.155
2.945AsnAsp: 2.945 ± 0.384
3.752AsnGlu: 3.752 ± 0.424
1.805AsnPhe: 1.805 ± 0.351
4.559AsnGly: 4.559 ± 0.677
0.807AsnHis: 0.807 ± 0.167
3.04AsnIle: 3.04 ± 0.413
3.134AsnLys: 3.134 ± 0.37
4.322AsnLeu: 4.322 ± 0.401
1.52AsnMet: 1.52 ± 0.226
2.755AsnAsn: 2.755 ± 0.373
3.847AsnPro: 3.847 ± 0.54
3.277AsnGln: 3.277 ± 0.52
2.422AsnArg: 2.422 ± 0.397
3.514AsnSer: 3.514 ± 0.347
2.992AsnThr: 2.992 ± 0.392
3.372AsnVal: 3.372 ± 0.459
0.475AsnTrp: 0.475 ± 0.194
2.042AsnTyr: 2.042 ± 0.316
0.0AsnXaa: 0.0 ± 0.0
Pro
2.517ProAla: 2.517 ± 0.326
0.38ProCys: 0.38 ± 0.171
2.897ProAsp: 2.897 ± 0.457
3.894ProGlu: 3.894 ± 0.473
1.71ProPhe: 1.71 ± 0.326
2.375ProGly: 2.375 ± 0.472
0.237ProHis: 0.237 ± 0.089
2.185ProIle: 2.185 ± 0.274
2.28ProLys: 2.28 ± 0.355
2.28ProLeu: 2.28 ± 0.305
1.045ProMet: 1.045 ± 0.228
2.707ProAsn: 2.707 ± 0.391
0.902ProPro: 0.902 ± 0.26
1.805ProGln: 1.805 ± 0.241
1.045ProArg: 1.045 ± 0.203
3.182ProSer: 3.182 ± 0.431
3.087ProThr: 3.087 ± 0.391
3.752ProVal: 3.752 ± 0.306
0.57ProTrp: 0.57 ± 0.218
1.377ProTyr: 1.377 ± 0.346
0.0ProXaa: 0.0 ± 0.0
Gln
4.037GlnAla: 4.037 ± 0.649
0.38GlnCys: 0.38 ± 0.152
2.802GlnAsp: 2.802 ± 0.383
3.229GlnGlu: 3.229 ± 0.565
1.947GlnPhe: 1.947 ± 0.306
2.802GlnGly: 2.802 ± 0.313
0.57GlnHis: 0.57 ± 0.19
3.182GlnIle: 3.182 ± 0.437
2.755GlnLys: 2.755 ± 0.359
4.797GlnLeu: 4.797 ± 0.563
1.567GlnMet: 1.567 ± 0.282
2.137GlnAsn: 2.137 ± 0.434
1.377GlnPro: 1.377 ± 0.302
2.707GlnGln: 2.707 ± 0.491
1.852GlnArg: 1.852 ± 0.261
2.565GlnSer: 2.565 ± 0.396
2.755GlnThr: 2.755 ± 0.494
2.375GlnVal: 2.375 ± 0.38
0.57GlnTrp: 0.57 ± 0.197
2.375GlnTyr: 2.375 ± 0.327
0.0GlnXaa: 0.0 ± 0.0
Arg
3.229ArgAla: 3.229 ± 0.453
0.475ArgCys: 0.475 ± 0.195
2.897ArgAsp: 2.897 ± 0.37
2.47ArgGlu: 2.47 ± 0.393
1.662ArgPhe: 1.662 ± 0.283
2.47ArgGly: 2.47 ± 0.325
0.665ArgHis: 0.665 ± 0.232
2.945ArgIle: 2.945 ± 0.403
2.945ArgLys: 2.945 ± 0.447
3.704ArgLeu: 3.704 ± 0.503
1.282ArgMet: 1.282 ± 0.238
2.137ArgAsn: 2.137 ± 0.385
1.045ArgPro: 1.045 ± 0.262
1.852ArgGln: 1.852 ± 0.312
1.472ArgArg: 1.472 ± 0.254
2.375ArgSer: 2.375 ± 0.364
2.992ArgThr: 2.992 ± 0.441
2.992ArgVal: 2.992 ± 0.374
0.427ArgTrp: 0.427 ± 0.125
1.235ArgTyr: 1.235 ± 0.202
0.0ArgXaa: 0.0 ± 0.0
Ser
4.892SerAla: 4.892 ± 0.492
0.617SerCys: 0.617 ± 0.196
3.419SerAsp: 3.419 ± 0.415
3.609SerGlu: 3.609 ± 0.452
2.47SerPhe: 2.47 ± 0.394
5.034SerGly: 5.034 ± 0.639
0.76SerHis: 0.76 ± 0.153
3.989SerIle: 3.989 ± 0.441
3.229SerLys: 3.229 ± 0.472
5.367SerLeu: 5.367 ± 0.493
1.567SerMet: 1.567 ± 0.357
3.894SerAsn: 3.894 ± 0.439
2.707SerPro: 2.707 ± 0.356
3.229SerGln: 3.229 ± 0.563
2.422SerArg: 2.422 ± 0.334
3.277SerSer: 3.277 ± 0.408
4.227SerThr: 4.227 ± 0.569
4.749SerVal: 4.749 ± 0.644
0.427SerTrp: 0.427 ± 0.148
1.9SerTyr: 1.9 ± 0.313
0.0SerXaa: 0.0 ± 0.0
Thr
4.559ThrAla: 4.559 ± 0.46
0.522ThrCys: 0.522 ± 0.172
3.704ThrAsp: 3.704 ± 0.438
3.942ThrGlu: 3.942 ± 0.514
1.805ThrPhe: 1.805 ± 0.227
4.797ThrGly: 4.797 ± 0.528
0.712ThrHis: 0.712 ± 0.203
3.657ThrIle: 3.657 ± 0.495
3.989ThrLys: 3.989 ± 0.464
4.559ThrLeu: 4.559 ± 0.46
1.282ThrMet: 1.282 ± 0.223
3.514ThrAsn: 3.514 ± 0.54
2.992ThrPro: 2.992 ± 0.449
3.087ThrGln: 3.087 ± 0.468
2.375ThrArg: 2.375 ± 0.37
3.514ThrSer: 3.514 ± 0.403
3.752ThrThr: 3.752 ± 0.603
5.652ThrVal: 5.652 ± 0.478
0.807ThrTrp: 0.807 ± 0.203
2.137ThrTyr: 2.137 ± 0.388
0.0ThrXaa: 0.0 ± 0.0
Val
5.177ValAla: 5.177 ± 0.479
0.237ValCys: 0.237 ± 0.137
4.702ValAsp: 4.702 ± 0.561
4.702ValGlu: 4.702 ± 0.572
2.755ValPhe: 2.755 ± 0.375
4.654ValGly: 4.654 ± 0.523
1.52ValHis: 1.52 ± 0.308
5.034ValIle: 5.034 ± 0.565
4.654ValLys: 4.654 ± 0.511
5.177ValLeu: 5.177 ± 0.586
1.567ValMet: 1.567 ± 0.281
3.894ValAsn: 3.894 ± 0.48
2.755ValPro: 2.755 ± 0.437
2.612ValGln: 2.612 ± 0.336
2.802ValArg: 2.802 ± 0.444
4.607ValSer: 4.607 ± 0.406
4.227ValThr: 4.227 ± 0.455
4.132ValVal: 4.132 ± 0.605
0.712ValTrp: 0.712 ± 0.217
2.47ValTyr: 2.47 ± 0.541
0.0ValXaa: 0.0 ± 0.0
Trp
0.712TrpAla: 0.712 ± 0.181
0.19TrpCys: 0.19 ± 0.085
0.855TrpAsp: 0.855 ± 0.275
0.57TrpGlu: 0.57 ± 0.135
0.712TrpPhe: 0.712 ± 0.252
0.902TrpGly: 0.902 ± 0.161
0.142TrpHis: 0.142 ± 0.086
0.665TrpIle: 0.665 ± 0.172
0.475TrpLys: 0.475 ± 0.159
0.997TrpLeu: 0.997 ± 0.277
0.38TrpMet: 0.38 ± 0.11
0.665TrpAsn: 0.665 ± 0.205
0.237TrpPro: 0.237 ± 0.107
0.237TrpGln: 0.237 ± 0.127
0.38TrpArg: 0.38 ± 0.121
0.285TrpSer: 0.285 ± 0.104
0.427TrpThr: 0.427 ± 0.114
0.95TrpVal: 0.95 ± 0.217
0.142TrpTrp: 0.142 ± 0.079
0.427TrpTyr: 0.427 ± 0.167
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.375TyrAla: 2.375 ± 0.357
0.38TyrCys: 0.38 ± 0.182
1.52TyrAsp: 1.52 ± 0.223
2.232TyrGlu: 2.232 ± 0.324
1.615TyrPhe: 1.615 ± 0.26
2.185TyrGly: 2.185 ± 0.384
0.855TyrHis: 0.855 ± 0.212
2.707TyrIle: 2.707 ± 0.436
2.47TyrLys: 2.47 ± 0.398
3.134TyrLeu: 3.134 ± 0.442
0.807TyrMet: 0.807 ± 0.212
1.9TyrAsn: 1.9 ± 0.293
1.377TyrPro: 1.377 ± 0.374
1.947TyrGln: 1.947 ± 0.373
1.235TyrArg: 1.235 ± 0.193
2.28TyrSer: 2.28 ± 0.336
1.995TyrThr: 1.995 ± 0.349
2.802TyrVal: 2.802 ± 0.432
0.237TyrTrp: 0.237 ± 0.1
1.282TyrTyr: 1.282 ± 0.296
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 82 proteins (21057 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski