Amino acid dipepetide frequency for Hubei tombus-like virus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.102AlaAla: 9.102 ± 3.049
0.607AlaCys: 0.607 ± 0.448
1.82AlaAsp: 1.82 ± 0.997
6.068AlaGlu: 6.068 ± 1.668
1.82AlaPhe: 1.82 ± 1.054
4.248AlaGly: 4.248 ± 1.651
1.82AlaHis: 1.82 ± 0.192
2.427AlaIle: 2.427 ± 0.987
6.675AlaLys: 6.675 ± 3.456
5.461AlaLeu: 5.461 ± 1.13
1.82AlaMet: 1.82 ± 0.785
3.034AlaAsn: 3.034 ± 2.24
5.461AlaPro: 5.461 ± 2.053
3.034AlaGln: 3.034 ± 1.462
7.888AlaArg: 7.888 ± 3.065
7.888AlaSer: 7.888 ± 1.852
4.854AlaThr: 4.854 ± 0.514
4.854AlaVal: 4.854 ± 1.335
1.82AlaTrp: 1.82 ± 0.997
0.607AlaTyr: 0.607 ± 0.571
0.0AlaXaa: 0.0 ± 0.0
Cys
1.214CysAla: 1.214 ± 0.639
0.607CysCys: 0.607 ± 0.448
0.607CysAsp: 0.607 ± 0.599
2.427CysGlu: 2.427 ± 0.722
0.0CysPhe: 0.0 ± 0.0
3.034CysGly: 3.034 ± 2.164
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
3.034CysLys: 3.034 ± 0.506
1.214CysLeu: 1.214 ± 0.896
0.607CysMet: 0.607 ± 0.571
0.607CysAsn: 0.607 ± 0.448
1.82CysPro: 1.82 ± 1.003
0.607CysGln: 0.607 ± 0.571
3.034CysArg: 3.034 ± 2.229
1.82CysSer: 1.82 ± 0.728
0.607CysThr: 0.607 ± 0.448
0.607CysVal: 0.607 ± 0.448
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.248AspAla: 4.248 ± 1.728
2.427AspCys: 2.427 ± 1.168
0.607AspAsp: 0.607 ± 0.571
4.854AspGlu: 4.854 ± 1.878
0.607AspPhe: 0.607 ± 0.448
3.641AspGly: 3.641 ± 0.383
1.214AspHis: 1.214 ± 0.52
3.034AspIle: 3.034 ± 0.506
1.214AspLys: 1.214 ± 0.896
4.248AspLeu: 4.248 ± 1.008
0.607AspMet: 0.607 ± 0.489
0.0AspAsn: 0.0 ± 0.0
4.248AspPro: 4.248 ± 1.003
3.034AspGln: 3.034 ± 0.484
3.034AspArg: 3.034 ± 1.696
3.034AspSer: 3.034 ± 1.255
0.607AspThr: 0.607 ± 0.448
1.82AspVal: 1.82 ± 0.728
0.607AspTrp: 0.607 ± 0.448
0.607AspTyr: 0.607 ± 0.448
0.0AspXaa: 0.0 ± 0.0
Glu
4.854GluAla: 4.854 ± 2.247
1.214GluCys: 1.214 ± 1.199
4.248GluAsp: 4.248 ± 2.452
7.282GluGlu: 7.282 ± 1.254
2.427GluPhe: 2.427 ± 2.286
3.641GluGly: 3.641 ± 1.271
2.427GluHis: 2.427 ± 1.279
4.854GluIle: 4.854 ± 2.082
4.248GluLys: 4.248 ± 2.266
9.102GluLeu: 9.102 ± 2.403
0.607GluMet: 0.607 ± 0.448
1.82GluAsn: 1.82 ± 1.344
4.854GluPro: 4.854 ± 1.335
6.068GluGln: 6.068 ± 2.902
6.068GluArg: 6.068 ± 1.65
3.034GluSer: 3.034 ± 2.229
1.82GluThr: 1.82 ± 1.344
6.068GluVal: 6.068 ± 1.668
1.82GluTrp: 1.82 ± 0.997
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.82PheAla: 1.82 ± 1.714
1.82PheCys: 1.82 ± 0.997
1.214PheAsp: 1.214 ± 0.639
1.82PheGlu: 1.82 ± 1.1
0.607PhePhe: 0.607 ± 0.448
1.82PheGly: 1.82 ± 0.997
0.607PheHis: 0.607 ± 0.448
1.214PheIle: 1.214 ± 1.143
1.82PheLys: 1.82 ± 0.785
2.427PheLeu: 2.427 ± 0.257
0.0PheMet: 0.0 ± 0.0
1.214PheAsn: 1.214 ± 0.52
0.0PhePro: 0.0 ± 0.0
1.82PheGln: 1.82 ± 0.192
1.82PheArg: 1.82 ± 0.192
0.607PheSer: 0.607 ± 0.448
1.214PheThr: 1.214 ± 0.896
0.607PheVal: 0.607 ± 0.448
0.0PheTrp: 0.0 ± 0.0
1.214PheTyr: 1.214 ± 1.143
0.0PheXaa: 0.0 ± 0.0
Gly
4.854GlyAla: 4.854 ± 1.975
1.214GlyCys: 1.214 ± 1.199
3.034GlyAsp: 3.034 ± 0.506
1.82GlyGlu: 1.82 ± 1.003
1.82GlyPhe: 1.82 ± 0.728
6.675GlyGly: 6.675 ± 1.587
1.214GlyHis: 1.214 ± 0.896
1.214GlyIle: 1.214 ± 0.639
4.854GlyLys: 4.854 ± 0.56
1.82GlyLeu: 1.82 ± 0.192
2.427GlyMet: 2.427 ± 1.394
3.034GlyAsn: 3.034 ± 1.313
3.034GlyPro: 3.034 ± 1.255
3.034GlyGln: 3.034 ± 2.164
3.641GlyArg: 3.641 ± 0.59
6.068GlySer: 6.068 ± 3.443
3.034GlyThr: 3.034 ± 0.484
4.248GlyVal: 4.248 ± 3.228
2.427GlyTrp: 2.427 ± 0.257
1.82GlyTyr: 1.82 ± 0.785
0.0GlyXaa: 0.0 ± 0.0
His
0.607HisAla: 0.607 ± 0.571
0.0HisCys: 0.0 ± 0.0
0.607HisAsp: 0.607 ± 0.571
0.607HisGlu: 0.607 ± 0.448
0.607HisPhe: 0.607 ± 0.571
3.641HisGly: 3.641 ± 0.59
1.214HisHis: 1.214 ± 1.143
0.607HisIle: 0.607 ± 0.448
0.0HisLys: 0.0 ± 0.0
2.427HisLeu: 2.427 ± 1.041
0.0HisMet: 0.0 ± 0.0
1.214HisAsn: 1.214 ± 0.896
1.214HisPro: 1.214 ± 0.494
3.641HisGln: 3.641 ± 1.455
3.034HisArg: 3.034 ± 1.484
1.82HisSer: 1.82 ± 0.192
1.82HisThr: 1.82 ± 1.344
1.214HisVal: 1.214 ± 1.143
0.0HisTrp: 0.0 ± 0.0
1.82HisTyr: 1.82 ± 1.054
0.0HisXaa: 0.0 ± 0.0
Ile
3.641IleAla: 3.641 ± 1.059
0.607IleCys: 0.607 ± 0.448
1.82IleAsp: 1.82 ± 1.714
2.427IleGlu: 2.427 ± 1.168
0.607IlePhe: 0.607 ± 0.448
0.607IleGly: 0.607 ± 0.448
0.0IleHis: 0.0 ± 0.0
1.214IleIle: 1.214 ± 1.143
2.427IleLys: 2.427 ± 1.168
0.0IleLeu: 0.0 ± 0.0
2.427IleMet: 2.427 ± 2.286
0.607IleAsn: 0.607 ± 0.571
1.214IlePro: 1.214 ± 0.639
1.82IleGln: 1.82 ± 1.054
4.248IleArg: 4.248 ± 0.959
3.641IleSer: 3.641 ± 0.656
1.82IleThr: 1.82 ± 0.997
1.82IleVal: 1.82 ± 0.997
0.607IleTrp: 0.607 ± 0.571
3.034IleTyr: 3.034 ± 0.831
0.0IleXaa: 0.0 ± 0.0
Lys
6.675LysAla: 6.675 ± 0.982
1.214LysCys: 1.214 ± 0.494
4.248LysAsp: 4.248 ± 2.384
4.248LysGlu: 4.248 ± 1.008
2.427LysPhe: 2.427 ± 1.041
4.854LysGly: 4.854 ± 1.39
4.248LysHis: 4.248 ± 1.753
1.82LysIle: 1.82 ± 1.054
3.034LysLys: 3.034 ± 1.255
3.034LysLeu: 3.034 ± 0.506
0.0LysMet: 0.0 ± 0.0
3.034LysAsn: 3.034 ± 0.506
3.034LysPro: 3.034 ± 0.506
4.854LysGln: 4.854 ± 0.546
4.248LysArg: 4.248 ± 0.068
6.068LysSer: 6.068 ± 0.968
1.82LysThr: 1.82 ± 0.997
3.034LysVal: 3.034 ± 0.705
0.0LysTrp: 0.0 ± 0.0
1.82LysTyr: 1.82 ± 0.728
0.0LysXaa: 0.0 ± 0.0
Leu
7.888LeuAla: 7.888 ± 1.014
1.82LeuCys: 1.82 ± 0.785
2.427LeuAsp: 2.427 ± 1.279
7.888LeuGlu: 7.888 ± 2.405
1.214LeuPhe: 1.214 ± 0.494
3.641LeuGly: 3.641 ± 1.271
2.427LeuHis: 2.427 ± 1.168
1.82LeuIle: 1.82 ± 0.785
2.427LeuLys: 2.427 ± 1.041
4.854LeuLeu: 4.854 ± 2.475
1.214LeuMet: 1.214 ± 1.143
2.427LeuAsn: 2.427 ± 0.257
3.641LeuPro: 3.641 ± 0.383
3.641LeuGln: 3.641 ± 1.481
7.282LeuArg: 7.282 ± 2.184
1.214LeuSer: 1.214 ± 0.639
1.82LeuThr: 1.82 ± 0.785
3.034LeuVal: 3.034 ± 1.255
0.0LeuTrp: 0.0 ± 0.0
1.214LeuTyr: 1.214 ± 0.639
0.0LeuXaa: 0.0 ± 0.0
Met
0.607MetAla: 0.607 ± 0.571
0.607MetCys: 0.607 ± 0.571
0.607MetAsp: 0.607 ± 0.571
3.034MetGlu: 3.034 ± 2.098
3.034MetPhe: 3.034 ± 1.258
1.214MetGly: 1.214 ± 1.199
0.607MetHis: 0.607 ± 0.448
0.607MetIle: 0.607 ± 0.571
2.427MetLys: 2.427 ± 1.041
0.0MetLeu: 0.0 ± 0.0
1.82MetMet: 1.82 ± 0.997
2.427MetAsn: 2.427 ± 1.792
2.427MetPro: 2.427 ± 0.695
1.82MetGln: 1.82 ± 0.785
0.607MetArg: 0.607 ± 0.571
0.607MetSer: 0.607 ± 0.571
3.034MetThr: 3.034 ± 1.585
1.82MetVal: 1.82 ± 0.785
0.607MetTrp: 0.607 ± 0.599
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.034AsnAla: 3.034 ± 1.585
0.0AsnCys: 0.0 ± 0.0
1.82AsnAsp: 1.82 ± 1.003
0.607AsnGlu: 0.607 ± 0.448
0.0AsnPhe: 0.0 ± 0.0
2.427AsnGly: 2.427 ± 1.168
1.82AsnHis: 1.82 ± 0.785
1.82AsnIle: 1.82 ± 0.192
4.248AsnLys: 4.248 ± 1.601
0.607AsnLeu: 0.607 ± 0.571
1.214AsnMet: 1.214 ± 1.2
8.495AsnAsn: 8.495 ± 6.271
4.248AsnPro: 4.248 ± 0.068
3.034AsnGln: 3.034 ± 1.16
3.034AsnArg: 3.034 ± 1.16
6.068AsnSer: 6.068 ± 2.718
1.82AsnThr: 1.82 ± 0.192
1.214AsnVal: 1.214 ± 0.52
0.607AsnTrp: 0.607 ± 0.448
0.607AsnTyr: 0.607 ± 0.571
0.0AsnXaa: 0.0 ± 0.0
Pro
4.854ProAla: 4.854 ± 1.975
1.82ProCys: 1.82 ± 0.192
4.248ProAsp: 4.248 ± 1.003
5.461ProGlu: 5.461 ± 1.145
0.607ProPhe: 0.607 ± 0.599
4.854ProGly: 4.854 ± 1.486
1.214ProHis: 1.214 ± 1.199
2.427ProIle: 2.427 ± 1.652
6.068ProLys: 6.068 ± 1.668
4.854ProLeu: 4.854 ± 0.56
3.641ProMet: 3.641 ± 1.048
1.214ProAsn: 1.214 ± 0.52
4.248ProPro: 4.248 ± 0.959
4.248ProGln: 4.248 ± 1.601
3.034ProArg: 3.034 ± 0.484
4.854ProSer: 4.854 ± 1.975
4.248ProThr: 4.248 ± 0.844
4.248ProVal: 4.248 ± 1.008
1.214ProTrp: 1.214 ± 0.639
1.214ProTyr: 1.214 ± 1.199
0.0ProXaa: 0.0 ± 0.0
Gln
4.854GlnAla: 4.854 ± 1.486
1.214GlnCys: 1.214 ± 0.494
0.607GlnAsp: 0.607 ± 0.448
2.427GlnGlu: 2.427 ± 0.987
1.214GlnPhe: 1.214 ± 0.52
3.641GlnGly: 3.641 ± 1.153
1.82GlnHis: 1.82 ± 0.192
2.427GlnIle: 2.427 ± 0.722
6.675GlnLys: 6.675 ± 2.634
5.461GlnLeu: 5.461 ± 0.563
3.034GlnMet: 3.034 ± 1.585
1.82GlnAsn: 1.82 ± 0.728
7.888GlnPro: 7.888 ± 3.629
18.204GlnGln: 18.204 ± 10.721
6.675GlnArg: 6.675 ± 3.459
5.461GlnSer: 5.461 ± 0.491
3.641GlnThr: 3.641 ± 1.271
1.214GlnVal: 1.214 ± 0.639
0.0GlnTrp: 0.0 ± 0.0
3.641GlnTyr: 3.641 ± 1.048
0.0GlnXaa: 0.0 ± 0.0
Arg
5.461ArgAla: 5.461 ± 1.448
2.427ArgCys: 2.427 ± 0.722
3.034ArgAsp: 3.034 ± 1.313
6.068ArgGlu: 6.068 ± 1.032
4.248ArgPhe: 4.248 ± 1.611
4.248ArgGly: 4.248 ± 1.806
2.427ArgHis: 2.427 ± 1.041
1.214ArgIle: 1.214 ± 0.52
4.854ArgLys: 4.854 ± 1.408
4.854ArgLeu: 4.854 ± 2.459
3.034ArgMet: 3.034 ± 1.255
5.461ArgAsn: 5.461 ± 0.962
5.461ArgPro: 5.461 ± 1.311
6.068ArgGln: 6.068 ± 2.635
10.316ArgArg: 10.316 ± 2.591
2.427ArgSer: 2.427 ± 1.652
2.427ArgThr: 2.427 ± 0.987
2.427ArgVal: 2.427 ± 0.987
3.034ArgTrp: 3.034 ± 1.484
1.82ArgTyr: 1.82 ± 0.192
0.0ArgXaa: 0.0 ± 0.0
Ser
7.282SerAla: 7.282 ± 0.455
1.214SerCys: 1.214 ± 1.199
3.641SerAsp: 3.641 ± 0.59
7.888SerGlu: 7.888 ± 2.709
1.214SerPhe: 1.214 ± 0.896
3.034SerGly: 3.034 ± 0.484
1.82SerHis: 1.82 ± 0.192
0.607SerIle: 0.607 ± 0.571
2.427SerLys: 2.427 ± 0.722
1.82SerLeu: 1.82 ± 0.785
3.034SerMet: 3.034 ± 0.831
4.248SerAsn: 4.248 ± 2.384
8.495SerPro: 8.495 ± 2.676
3.641SerGln: 3.641 ± 1.153
3.034SerArg: 3.034 ± 0.506
3.034SerSer: 3.034 ± 1.16
4.248SerThr: 4.248 ± 1.628
3.641SerVal: 3.641 ± 0.656
0.0SerTrp: 0.0 ± 0.0
1.82SerTyr: 1.82 ± 1.1
0.0SerXaa: 0.0 ± 0.0
Thr
3.034ThrAla: 3.034 ± 0.506
1.214ThrCys: 1.214 ± 1.199
3.034ThrAsp: 3.034 ± 0.705
3.641ThrGlu: 3.641 ± 1.57
0.0ThrPhe: 0.0 ± 0.0
2.427ThrGly: 2.427 ± 1.792
0.0ThrHis: 0.0 ± 0.0
3.034ThrIle: 3.034 ± 1.484
3.641ThrLys: 3.641 ± 2.005
2.427ThrLeu: 2.427 ± 1.103
0.607ThrMet: 0.607 ± 0.571
1.214ThrAsn: 1.214 ± 0.494
3.641ThrPro: 3.641 ± 1.994
2.427ThrGln: 2.427 ± 0.257
4.248ThrArg: 4.248 ± 2.384
4.854ThrSer: 4.854 ± 1.335
3.641ThrThr: 3.641 ± 1.059
1.214ThrVal: 1.214 ± 0.52
0.607ThrTrp: 0.607 ± 0.599
1.82ThrTyr: 1.82 ± 0.192
0.0ThrXaa: 0.0 ± 0.0
Val
3.641ValAla: 3.641 ± 1.57
0.0ValCys: 0.0 ± 0.0
3.641ValAsp: 3.641 ± 1.048
4.854ValGlu: 4.854 ± 0.514
1.214ValPhe: 1.214 ± 0.52
1.82ValGly: 1.82 ± 0.192
0.607ValHis: 0.607 ± 0.571
1.82ValIle: 1.82 ± 0.997
1.214ValLys: 1.214 ± 0.896
4.248ValLeu: 4.248 ± 0.844
0.607ValMet: 0.607 ± 0.448
3.641ValAsn: 3.641 ± 1.561
2.427ValPro: 2.427 ± 1.041
5.461ValGln: 5.461 ± 3.267
2.427ValArg: 2.427 ± 0.695
2.427ValSer: 2.427 ± 0.257
1.214ValThr: 1.214 ± 1.143
2.427ValVal: 2.427 ± 1.041
0.0ValTrp: 0.0 ± 0.0
1.82ValTyr: 1.82 ± 1.054
0.0ValXaa: 0.0 ± 0.0
Trp
0.607TrpAla: 0.607 ± 0.448
1.214TrpCys: 1.214 ± 1.199
0.607TrpAsp: 0.607 ± 0.571
1.82TrpGlu: 1.82 ± 0.785
0.0TrpPhe: 0.0 ± 0.0
1.214TrpGly: 1.214 ± 1.143
0.0TrpHis: 0.0 ± 0.0
1.214TrpIle: 1.214 ± 0.896
1.214TrpLys: 1.214 ± 1.143
0.607TrpLeu: 0.607 ± 0.599
0.0TrpMet: 0.0 ± 0.0
0.607TrpAsn: 0.607 ± 0.571
0.607TrpPro: 0.607 ± 0.599
2.427TrpGln: 2.427 ± 1.041
1.214TrpArg: 1.214 ± 0.639
0.0TrpSer: 0.0 ± 0.0
0.607TrpThr: 0.607 ± 0.448
0.0TrpVal: 0.0 ± 0.0
0.607TrpTrp: 0.607 ± 0.571
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.034TyrAla: 3.034 ± 1.647
0.607TyrCys: 0.607 ± 0.599
1.82TyrAsp: 1.82 ± 1.1
1.214TyrGlu: 1.214 ± 0.494
0.0TyrPhe: 0.0 ± 0.0
0.607TyrGly: 0.607 ± 0.571
0.607TyrHis: 0.607 ± 0.448
1.214TyrIle: 1.214 ± 0.52
1.214TyrLys: 1.214 ± 1.143
2.427TyrLeu: 2.427 ± 2.286
0.607TyrMet: 0.607 ± 0.448
1.214TyrAsn: 1.214 ± 0.639
0.607TyrPro: 0.607 ± 0.448
3.034TyrGln: 3.034 ± 0.831
2.427TyrArg: 2.427 ± 1.279
1.214TyrSer: 1.214 ± 0.52
2.427TyrThr: 2.427 ± 1.103
0.0TyrVal: 0.0 ± 0.0
0.607TyrTrp: 0.607 ± 0.599
1.214TyrTyr: 1.214 ± 0.639
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1649 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski