Amino acid dipepetide frequency for Thalassotalea mangrovi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.444AlaAla: 7.444 ± 0.117	0.989AlaCys: 0.989 ± 0.03	5.187AlaAsp: 5.187 ± 0.08	5.521AlaGlu: 5.521 ± 0.073	3.398AlaPhe: 3.398 ± 0.061	6.112AlaGly: 6.112 ± 0.091	1.567AlaHis: 1.567 ± 0.043	6.14AlaIle: 6.14 ± 0.093	4.81AlaLys: 4.81 ± 0.08	9.203AlaLeu: 9.203 ± 0.109	2.616AlaMet: 2.616 ± 0.05	4.107AlaAsn: 4.107 ± 0.06	2.829AlaPro: 2.829 ± 0.053	3.877AlaGln: 3.877 ± 0.074	3.776AlaArg: 3.776 ± 0.067	5.489AlaSer: 5.489 ± 0.069	4.558AlaThr: 4.558 ± 0.065	5.494AlaVal: 5.494 ± 0.08	0.977AlaTrp: 0.977 ± 0.027	2.478AlaTyr: 2.478 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.827CysAla: 0.827 ± 0.028	0.156CysCys: 0.156 ± 0.014	0.609CysAsp: 0.609 ± 0.026	0.593CysGlu: 0.593 ± 0.028	0.439CysPhe: 0.439 ± 0.015	0.819CysGly: 0.819 ± 0.033	0.34CysHis: 0.34 ± 0.022	0.614CysIle: 0.614 ± 0.028	0.39CysLys: 0.39 ± 0.021	0.984CysLeu: 0.984 ± 0.034	0.212CysMet: 0.212 ± 0.012	0.396CysAsn: 0.396 ± 0.021	0.483CysPro: 0.483 ± 0.02	0.631CysGln: 0.631 ± 0.023	0.482CysArg: 0.482 ± 0.021	0.707CysSer: 0.707 ± 0.029	0.427CysThr: 0.427 ± 0.021	0.549CysVal: 0.549 ± 0.021	0.134CysTrp: 0.134 ± 0.012	0.322CysTyr: 0.322 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	4.673AspAla: 4.673 ± 0.075	0.602AspCys: 0.602 ± 0.026	3.652AspAsp: 3.652 ± 0.066	3.909AspGlu: 3.909 ± 0.072	2.729AspPhe: 2.729 ± 0.057	3.98AspGly: 3.98 ± 0.073	1.12AspHis: 1.12 ± 0.035	4.579AspIle: 4.579 ± 0.06	3.469AspLys: 3.469 ± 0.057	5.342AspLeu: 5.342 ± 0.072	1.516AspMet: 1.516 ± 0.038	3.079AspAsn: 3.079 ± 0.06	2.196AspPro: 2.196 ± 0.047	2.039AspGln: 2.039 ± 0.049	2.253AspArg: 2.253 ± 0.041	3.499AspSer: 3.499 ± 0.061	2.75AspThr: 2.75 ± 0.056	4.051AspVal: 4.051 ± 0.074	0.93AspTrp: 0.93 ± 0.029	2.366AspTyr: 2.366 ± 0.053	0.0AspXaa: 0.0 ± 0.0
Glu	4.469GluAla: 4.469 ± 0.074	0.447GluCys: 0.447 ± 0.022	3.078GluAsp: 3.078 ± 0.06	3.437GluGlu: 3.437 ± 0.064	2.651GluPhe: 2.651 ± 0.051	3.251GluGly: 3.251 ± 0.062	1.591GluHis: 1.591 ± 0.04	3.752GluIle: 3.752 ± 0.059	3.564GluLys: 3.564 ± 0.065	6.667GluLeu: 6.667 ± 0.086	1.617GluMet: 1.617 ± 0.042	2.952GluAsn: 2.952 ± 0.052	2.091GluPro: 2.091 ± 0.047	4.832GluGln: 4.832 ± 0.078	3.083GluArg: 3.083 ± 0.054	3.378GluSer: 3.378 ± 0.06	2.856GluThr: 2.856 ± 0.058	3.934GluVal: 3.934 ± 0.066	0.623GluTrp: 0.623 ± 0.025	1.859GluTyr: 1.859 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	4.011PheAla: 4.011 ± 0.064	0.49PheCys: 0.49 ± 0.02	3.036PheAsp: 3.036 ± 0.055	2.514PheGlu: 2.514 ± 0.051	1.818PhePhe: 1.818 ± 0.046	3.068PheGly: 3.068 ± 0.063	0.853PheHis: 0.853 ± 0.029	3.049PheIle: 3.049 ± 0.062	1.978PheLys: 1.978 ± 0.042	3.48PheLeu: 3.48 ± 0.061	1.011PheMet: 1.011 ± 0.034	2.278PheAsn: 2.278 ± 0.045	1.485PhePro: 1.485 ± 0.034	1.409PheGln: 1.409 ± 0.033	1.608PheArg: 1.608 ± 0.038	3.52PheSer: 3.52 ± 0.062	2.516PheThr: 2.516 ± 0.047	2.716PheVal: 2.716 ± 0.065	0.579PheTrp: 0.579 ± 0.026	1.556PheTyr: 1.556 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	5.234GlyAla: 5.234 ± 0.085	0.851GlyCys: 0.851 ± 0.027	3.984GlyAsp: 3.984 ± 0.069	4.248GlyGlu: 4.248 ± 0.074	3.504GlyPhe: 3.504 ± 0.061	4.77GlyGly: 4.77 ± 0.093	1.588GlyHis: 1.588 ± 0.04	4.762GlyIle: 4.762 ± 0.085	4.094GlyLys: 4.094 ± 0.074	6.882GlyLeu: 6.882 ± 0.091	2.038GlyMet: 2.038 ± 0.045	2.936GlyAsn: 2.936 ± 0.061	1.782GlyPro: 1.782 ± 0.041	2.901GlyGln: 2.901 ± 0.056	2.994GlyArg: 2.994 ± 0.058	4.083GlySer: 4.083 ± 0.067	3.283GlyThr: 3.283 ± 0.065	4.919GlyVal: 4.919 ± 0.08	1.004GlyTrp: 1.004 ± 0.032	2.66GlyTyr: 2.66 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.514HisAla: 1.514 ± 0.039	0.329HisCys: 0.329 ± 0.021	1.063HisAsp: 1.063 ± 0.03	1.023HisGlu: 1.023 ± 0.034	1.17HisPhe: 1.17 ± 0.037	1.721HisGly: 1.721 ± 0.04	0.678HisHis: 0.678 ± 0.027	1.38HisIle: 1.38 ± 0.036	1.018HisLys: 1.018 ± 0.031	2.307HisLeu: 2.307 ± 0.054	0.501HisMet: 0.501 ± 0.02	0.949HisAsn: 0.949 ± 0.029	1.252HisPro: 1.252 ± 0.034	1.397HisGln: 1.397 ± 0.038	1.127HisArg: 1.127 ± 0.035	1.327HisSer: 1.327 ± 0.035	0.984HisThr: 0.984 ± 0.03	1.207HisVal: 1.207 ± 0.04	0.387HisTrp: 0.387 ± 0.02	0.903HisTyr: 0.903 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	6.603IleAla: 6.603 ± 0.099	0.692IleCys: 0.692 ± 0.029	4.738IleAsp: 4.738 ± 0.07	4.593IleGlu: 4.593 ± 0.073	2.388IlePhe: 2.388 ± 0.053	4.613IleGly: 4.613 ± 0.068	1.3IleHis: 1.3 ± 0.036	3.942IleIle: 3.942 ± 0.075	3.351IleLys: 3.351 ± 0.059	5.307IleLeu: 5.307 ± 0.079	1.24IleMet: 1.24 ± 0.041	3.278IleAsn: 3.278 ± 0.053	2.572IlePro: 2.572 ± 0.054	2.238IleGln: 2.238 ± 0.05	2.974IleArg: 2.974 ± 0.057	4.528IleSer: 4.528 ± 0.065	3.6IleThr: 3.6 ± 0.064	3.936IleVal: 3.936 ± 0.058	0.672IleTrp: 0.672 ± 0.027	1.888IleTyr: 1.888 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	4.809LysAla: 4.809 ± 0.086	0.322LysCys: 0.322 ± 0.021	2.739LysAsp: 2.739 ± 0.053	2.817LysGlu: 2.817 ± 0.066	1.796LysPhe: 1.796 ± 0.042	3.087LysGly: 3.087 ± 0.057	1.203LysHis: 1.203 ± 0.035	3.001LysIle: 3.001 ± 0.056	2.66LysLys: 2.66 ± 0.062	5.027LysLeu: 5.027 ± 0.088	1.29LysMet: 1.29 ± 0.034	2.076LysAsn: 2.076 ± 0.043	2.367LysPro: 2.367 ± 0.053	2.966LysGln: 2.966 ± 0.055	2.708LysArg: 2.708 ± 0.053	3.225LysSer: 3.225 ± 0.06	2.864LysThr: 2.864 ± 0.059	3.872LysVal: 3.872 ± 0.057	0.481LysTrp: 0.481 ± 0.021	1.485LysTyr: 1.485 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	10.205LeuAla: 10.205 ± 0.133	0.979LeuCys: 0.979 ± 0.029	5.704LeuAsp: 5.704 ± 0.08	5.477LeuGlu: 5.477 ± 0.08	4.184LeuPhe: 4.184 ± 0.071	6.66LeuGly: 6.66 ± 0.099	2.053LeuHis: 2.053 ± 0.048	6.412LeuIle: 6.412 ± 0.095	4.957LeuLys: 4.957 ± 0.073	10.704LeuLeu: 10.704 ± 0.159	2.554LeuMet: 2.554 ± 0.047	4.669LeuAsn: 4.669 ± 0.075	4.605LeuPro: 4.605 ± 0.072	4.852LeuGln: 4.852 ± 0.092	4.063LeuArg: 4.063 ± 0.072	7.258LeuSer: 7.258 ± 0.088	6.15LeuThr: 6.15 ± 0.066	6.88LeuVal: 6.88 ± 0.09	1.055LeuTrp: 1.055 ± 0.035	2.699LeuTyr: 2.699 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.659MetAla: 2.659 ± 0.051	0.181MetCys: 0.181 ± 0.012	1.256MetAsp: 1.256 ± 0.035	1.266MetGlu: 1.266 ± 0.036	0.982MetPhe: 0.982 ± 0.028	1.639MetGly: 1.639 ± 0.035	0.5MetHis: 0.5 ± 0.022	1.441MetIle: 1.441 ± 0.042	1.326MetLys: 1.326 ± 0.04	2.675MetLeu: 2.675 ± 0.046	0.752MetMet: 0.752 ± 0.028	1.036MetAsn: 1.036 ± 0.032	1.189MetPro: 1.189 ± 0.035	1.286MetGln: 1.286 ± 0.038	1.175MetArg: 1.175 ± 0.034	1.8MetSer: 1.8 ± 0.047	1.544MetThr: 1.544 ± 0.038	1.853MetVal: 1.853 ± 0.04	0.224MetTrp: 0.224 ± 0.013	0.569MetTyr: 0.569 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.599AsnAla: 3.599 ± 0.059	0.473AsnCys: 0.473 ± 0.018	2.628AsnAsp: 2.628 ± 0.045	2.581AsnGlu: 2.581 ± 0.048	1.692AsnPhe: 1.692 ± 0.036	3.098AsnGly: 3.098 ± 0.062	1.058AsnHis: 1.058 ± 0.034	3.032AsnIle: 3.032 ± 0.055	2.244AsnLys: 2.244 ± 0.053	4.313AsnLeu: 4.313 ± 0.07	1.082AsnMet: 1.082 ± 0.028	2.035AsnAsn: 2.035 ± 0.053	2.347AsnPro: 2.347 ± 0.044	2.367AsnGln: 2.367 ± 0.047	2.203AsnArg: 2.203 ± 0.042	2.534AsnSer: 2.534 ± 0.05	2.258AsnThr: 2.258 ± 0.053	2.789AsnVal: 2.789 ± 0.054	0.656AsnTrp: 0.656 ± 0.026	1.475AsnTyr: 1.475 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	3.173ProAla: 3.173 ± 0.065	0.305ProCys: 0.305 ± 0.017	2.632ProAsp: 2.632 ± 0.051	3.334ProGlu: 3.334 ± 0.058	1.762ProPhe: 1.762 ± 0.04	3.086ProGly: 3.086 ± 0.062	0.817ProHis: 0.817 ± 0.03	2.179ProIle: 2.179 ± 0.046	1.895ProLys: 1.895 ± 0.05	4.021ProLeu: 4.021 ± 0.064	1.029ProMet: 1.029 ± 0.028	1.555ProAsn: 1.555 ± 0.04	1.048ProPro: 1.048 ± 0.035	1.887ProGln: 1.887 ± 0.042	1.376ProArg: 1.376 ± 0.035	2.192ProSer: 2.192 ± 0.048	1.888ProThr: 1.888 ± 0.044	3.331ProVal: 3.331 ± 0.061	0.512ProTrp: 0.512 ± 0.025	1.291ProTyr: 1.291 ± 0.044	0.0ProXaa: 0.0 ± 0.0
Gln	4.775GlnAla: 4.775 ± 0.085	0.42GlnCys: 0.42 ± 0.023	2.37GlnAsp: 2.37 ± 0.041	2.687GlnGlu: 2.687 ± 0.051	1.963GlnPhe: 1.963 ± 0.04	3.371GlnGly: 3.371 ± 0.068	1.406GlnHis: 1.406 ± 0.035	2.756GlnIle: 2.756 ± 0.046	2.283GlnLys: 2.283 ± 0.054	5.84GlnLeu: 5.84 ± 0.101	1.137GlnMet: 1.137 ± 0.038	1.719GlnAsn: 1.719 ± 0.041	1.975GlnPro: 1.975 ± 0.042	4.668GlnGln: 4.668 ± 0.093	2.675GlnArg: 2.675 ± 0.064	3.031GlnSer: 3.031 ± 0.059	2.31GlnThr: 2.31 ± 0.051	3.73GlnVal: 3.73 ± 0.061	0.705GlnTrp: 0.705 ± 0.022	1.533GlnTyr: 1.533 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	3.39ArgAla: 3.39 ± 0.069	0.46ArgCys: 0.46 ± 0.021	2.548ArgAsp: 2.548 ± 0.05	2.856ArgGlu: 2.856 ± 0.047	2.295ArgPhe: 2.295 ± 0.047	2.671ArgGly: 2.671 ± 0.056	1.156ArgHis: 1.156 ± 0.036	3.063ArgIle: 3.063 ± 0.059	2.284ArgLys: 2.284 ± 0.049	4.908ArgLeu: 4.908 ± 0.08	1.206ArgMet: 1.206 ± 0.031	1.964ArgAsn: 1.964 ± 0.048	1.655ArgPro: 1.655 ± 0.039	2.775ArgGln: 2.775 ± 0.069	2.323ArgArg: 2.323 ± 0.048	2.454ArgSer: 2.454 ± 0.055	1.904ArgThr: 1.904 ± 0.041	3.044ArgVal: 3.044 ± 0.051	0.651ArgTrp: 0.651 ± 0.027	1.755ArgTyr: 1.755 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	5.447SerAla: 5.447 ± 0.081	0.625SerCys: 0.625 ± 0.022	3.738SerAsp: 3.738 ± 0.065	3.975SerGlu: 3.975 ± 0.071	2.89SerPhe: 2.89 ± 0.052	5.103SerGly: 5.103 ± 0.069	1.399SerHis: 1.399 ± 0.04	3.874SerIle: 3.874 ± 0.056	3.202SerLys: 3.202 ± 0.058	6.728SerLeu: 6.728 ± 0.085	1.626SerMet: 1.626 ± 0.041	2.605SerAsn: 2.605 ± 0.054	2.384SerPro: 2.384 ± 0.049	3.032SerGln: 3.032 ± 0.055	2.86SerArg: 2.86 ± 0.059	4.037SerSer: 4.037 ± 0.06	2.952SerThr: 2.952 ± 0.06	4.374SerVal: 4.374 ± 0.066	0.875SerTrp: 0.875 ± 0.03	2.059SerTyr: 2.059 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	4.395ThrAla: 4.395 ± 0.073	0.485ThrCys: 0.485 ± 0.022	3.111ThrAsp: 3.111 ± 0.063	3.02ThrGlu: 3.02 ± 0.055	2.209ThrPhe: 2.209 ± 0.051	4.181ThrGly: 4.181 ± 0.076	1.035ThrHis: 1.035 ± 0.031	3.297ThrIle: 3.297 ± 0.056	1.988ThrLys: 1.988 ± 0.04	5.963ThrLeu: 5.963 ± 0.074	1.149ThrMet: 1.149 ± 0.035	1.921ThrAsn: 1.921 ± 0.041	2.57ThrPro: 2.57 ± 0.046	2.127ThrGln: 2.127 ± 0.046	2.248ThrArg: 2.248 ± 0.046	3.279ThrSer: 3.279 ± 0.053	2.693ThrThr: 2.693 ± 0.06	3.579ThrVal: 3.579 ± 0.062	0.589ThrTrp: 0.589 ± 0.024	1.567ThrTyr: 1.567 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	6.157ValAla: 6.157 ± 0.082	0.773ValCys: 0.773 ± 0.031	4.325ValAsp: 4.325 ± 0.065	4.254ValGlu: 4.254 ± 0.075	2.921ValPhe: 2.921 ± 0.058	4.214ValGly: 4.214 ± 0.066	1.282ValHis: 1.282 ± 0.036	4.869ValIle: 4.869 ± 0.076	3.552ValLys: 3.552 ± 0.065	6.37ValLeu: 6.37 ± 0.086	1.759ValMet: 1.759 ± 0.043	3.348ValAsn: 3.348 ± 0.058	2.55ValPro: 2.55 ± 0.053	2.289ValGln: 2.289 ± 0.05	2.842ValArg: 2.842 ± 0.059	4.735ValSer: 4.735 ± 0.068	3.919ValThr: 3.919 ± 0.063	4.819ValVal: 4.819 ± 0.084	0.776ValTrp: 0.776 ± 0.032	1.968ValTyr: 1.968 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.782TrpAla: 0.782 ± 0.028	0.139TrpCys: 0.139 ± 0.012	0.588TrpAsp: 0.588 ± 0.023	0.48TrpGlu: 0.48 ± 0.023	0.622TrpPhe: 0.622 ± 0.028	0.823TrpGly: 0.823 ± 0.031	0.408TrpHis: 0.408 ± 0.02	0.625TrpIle: 0.625 ± 0.026	0.412TrpLys: 0.412 ± 0.019	1.725TrpLeu: 1.725 ± 0.05	0.349TrpMet: 0.349 ± 0.019	0.414TrpAsn: 0.414 ± 0.021	0.487TrpPro: 0.487 ± 0.025	1.31TrpGln: 1.31 ± 0.039	0.707TrpArg: 0.707 ± 0.025	0.715TrpSer: 0.715 ± 0.029	0.496TrpThr: 0.496 ± 0.024	0.805TrpVal: 0.805 ± 0.032	0.187TrpTrp: 0.187 ± 0.014	0.443TrpTyr: 0.443 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.406TyrAla: 2.406 ± 0.047	0.396TyrCys: 0.396 ± 0.023	1.745TyrAsp: 1.745 ± 0.043	1.547TyrGlu: 1.547 ± 0.042	1.563TyrPhe: 1.563 ± 0.041	2.247TyrGly: 2.247 ± 0.052	0.884TyrHis: 0.884 ± 0.029	1.687TyrIle: 1.687 ± 0.039	1.316TyrLys: 1.316 ± 0.041	3.678TyrLeu: 3.678 ± 0.059	0.666TyrMet: 0.666 ± 0.03	1.145TyrAsn: 1.145 ± 0.038	1.447TyrPro: 1.447 ± 0.037	2.47TyrGln: 2.47 ± 0.045	1.888TyrArg: 1.888 ± 0.048	1.995TyrSer: 1.995 ± 0.053	1.458TyrThr: 1.458 ± 0.044	1.837TyrVal: 1.837 ± 0.043	0.501TyrTrp: 0.501 ± 0.024	1.2TyrTyr: 1.2 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3157 proteins (1056890 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---