Amino acid dipepetide frequency for Capra hircus (Goat)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.149AlaAla: 7.149 ± 0.037	1.444AlaCys: 1.444 ± 0.011	2.983AlaAsp: 2.983 ± 0.013	4.886AlaGlu: 4.886 ± 0.024	2.695AlaPhe: 2.695 ± 0.014	4.937AlaGly: 4.937 ± 0.022	1.609AlaHis: 1.609 ± 0.01	2.744AlaIle: 2.744 ± 0.015	3.414AlaLys: 3.414 ± 0.017	7.31AlaLeu: 7.31 ± 0.031	1.432AlaMet: 1.432 ± 0.009	1.996AlaAsn: 1.996 ± 0.011	4.51AlaPro: 4.51 ± 0.028	3.251AlaGln: 3.251 ± 0.018	3.797AlaArg: 3.797 ± 0.019	5.891AlaSer: 5.891 ± 0.023	3.496AlaThr: 3.496 ± 0.014	4.834AlaVal: 4.834 ± 0.018	0.817AlaTrp: 0.817 ± 0.007	1.547AlaTyr: 1.547 ± 0.008	0.0AlaXaa: 0.0 ± 0.0
Cys	1.323CysAla: 1.323 ± 0.01	0.652CysCys: 0.652 ± 0.012	1.072CysAsp: 1.072 ± 0.012	1.291CysGlu: 1.291 ± 0.011	0.859CysPhe: 0.859 ± 0.008	1.745CysGly: 1.745 ± 0.019	0.657CysHis: 0.657 ± 0.007	0.948CysIle: 0.948 ± 0.009	1.123CysLys: 1.123 ± 0.01	2.197CysLeu: 2.197 ± 0.014	0.396CysMet: 0.396 ± 0.004	0.782CysAsn: 0.782 ± 0.007	1.419CysPro: 1.419 ± 0.014	1.082CysGln: 1.082 ± 0.011	1.327CysArg: 1.327 ± 0.011	2.033CysSer: 2.033 ± 0.014	1.075CysThr: 1.075 ± 0.01	1.336CysVal: 1.336 ± 0.012	0.289CysTrp: 0.289 ± 0.004	0.579CysTyr: 0.579 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.972AspAla: 2.972 ± 0.016	1.071AspCys: 1.071 ± 0.012	2.628AspAsp: 2.628 ± 0.016	3.465AspGlu: 3.465 ± 0.016	2.129AspPhe: 2.129 ± 0.011	3.344AspGly: 3.344 ± 0.019	1.137AspHis: 1.137 ± 0.008	2.552AspIle: 2.552 ± 0.017	2.467AspLys: 2.467 ± 0.013	5.019AspLeu: 5.019 ± 0.019	1.065AspMet: 1.065 ± 0.008	1.634AspAsn: 1.634 ± 0.012	2.939AspPro: 2.939 ± 0.013	1.849AspGln: 1.849 ± 0.01	2.485AspArg: 2.485 ± 0.014	4.207AspSer: 4.207 ± 0.022	2.443AspThr: 2.443 ± 0.013	3.102AspVal: 3.102 ± 0.027	0.639AspTrp: 0.639 ± 0.007	1.468AspTyr: 1.468 ± 0.009	0.0AspXaa: 0.0 ± 0.0
Glu	5.354GluAla: 5.354 ± 0.024	1.392GluCys: 1.392 ± 0.016	4.438GluAsp: 4.438 ± 0.019	7.802GluGlu: 7.802 ± 0.041	2.041GluPhe: 2.041 ± 0.012	4.292GluGly: 4.292 ± 0.018	1.483GluHis: 1.483 ± 0.01	3.087GluIle: 3.087 ± 0.015	5.331GluLys: 5.331 ± 0.028	6.484GluLeu: 6.484 ± 0.027	1.649GluMet: 1.649 ± 0.01	3.064GluAsn: 3.064 ± 0.018	3.334GluPro: 3.334 ± 0.019	3.093GluGln: 3.093 ± 0.019	4.024GluArg: 4.024 ± 0.021	4.414GluSer: 4.414 ± 0.019	3.364GluThr: 3.364 ± 0.015	4.179GluVal: 4.179 ± 0.02	0.691GluTrp: 0.691 ± 0.006	1.547GluTyr: 1.547 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	1.98PheAla: 1.98 ± 0.011	0.953PheCys: 0.953 ± 0.008	1.676PheAsp: 1.676 ± 0.011	1.997PheGlu: 1.997 ± 0.012	1.637PhePhe: 1.637 ± 0.011	2.23PheGly: 2.23 ± 0.014	1.043PheHis: 1.043 ± 0.007	1.834PheIle: 1.834 ± 0.012	1.754PheLys: 1.754 ± 0.012	4.201PheLeu: 4.201 ± 0.022	0.758PheMet: 0.758 ± 0.006	1.333PheAsn: 1.333 ± 0.009	2.022PhePro: 2.022 ± 0.013	1.775PheGln: 1.775 ± 0.01	2.006PheArg: 2.006 ± 0.012	3.491PheSer: 3.491 ± 0.016	2.041PheThr: 2.041 ± 0.012	2.176PheVal: 2.176 ± 0.01	0.502PheTrp: 0.502 ± 0.006	1.216PheTyr: 1.216 ± 0.008	0.0PheXaa: 0.0 ± 0.0
Gly	4.722GlyAla: 4.722 ± 0.021	1.312GlyCys: 1.312 ± 0.012	3.163GlyAsp: 3.163 ± 0.016	4.149GlyGlu: 4.149 ± 0.022	2.416GlyPhe: 2.416 ± 0.016	5.221GlyGly: 5.221 ± 0.036	1.683GlyHis: 1.683 ± 0.013	2.683GlyIle: 2.683 ± 0.014	3.751GlyLys: 3.751 ± 0.019	5.941GlyLeu: 5.941 ± 0.02	1.248GlyMet: 1.248 ± 0.01	2.336GlyAsn: 2.336 ± 0.014	4.446GlyPro: 4.446 ± 0.039	2.8GlyGln: 2.8 ± 0.018	3.938GlyArg: 3.938 ± 0.019	5.898GlySer: 5.898 ± 0.023	3.539GlyThr: 3.539 ± 0.019	3.584GlyVal: 3.584 ± 0.016	0.812GlyTrp: 0.812 ± 0.008	1.744GlyTyr: 1.744 ± 0.012	0.0GlyXaa: 0.0 ± 0.0
His	1.329HisAla: 1.329 ± 0.008	0.721HisCys: 0.721 ± 0.008	0.883HisAsp: 0.883 ± 0.008	1.281HisGlu: 1.281 ± 0.009	1.097HisPhe: 1.097 ± 0.008	1.573HisGly: 1.573 ± 0.013	0.881HisHis: 0.881 ± 0.01	1.206HisIle: 1.206 ± 0.008	1.221HisLys: 1.221 ± 0.009	2.94HisLeu: 2.94 ± 0.016	0.571HisMet: 0.571 ± 0.006	0.811HisAsn: 0.811 ± 0.007	1.663HisPro: 1.663 ± 0.013	1.338HisGln: 1.338 ± 0.013	1.596HisArg: 1.596 ± 0.01	2.286HisSer: 2.286 ± 0.015	1.509HisThr: 1.509 ± 0.015	1.523HisVal: 1.523 ± 0.009	0.341HisTrp: 0.341 ± 0.005	0.792HisTyr: 0.792 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.526IleAla: 2.526 ± 0.013	1.084IleCys: 1.084 ± 0.008	1.947IleAsp: 1.947 ± 0.012	2.492IleGlu: 2.492 ± 0.015	1.889IlePhe: 1.889 ± 0.013	2.152IleGly: 2.152 ± 0.012	1.319IleHis: 1.319 ± 0.012	2.317IleIle: 2.317 ± 0.015	2.539IleLys: 2.539 ± 0.016	4.564IleLeu: 4.564 ± 0.021	0.963IleMet: 0.963 ± 0.007	1.79IleAsn: 1.79 ± 0.011	2.531IlePro: 2.531 ± 0.013	2.258IleGln: 2.258 ± 0.014	2.345IleArg: 2.345 ± 0.013	3.68IleSer: 3.68 ± 0.017	2.525IleThr: 2.525 ± 0.013	2.466IleVal: 2.466 ± 0.014	0.506IleTrp: 0.506 ± 0.006	1.373IleTyr: 1.373 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	4.034LysAla: 4.034 ± 0.02	1.12LysCys: 1.12 ± 0.012	3.117LysAsp: 3.117 ± 0.016	5.035LysGlu: 5.035 ± 0.025	1.703LysPhe: 1.703 ± 0.011	3.194LysGly: 3.194 ± 0.026	1.354LysHis: 1.354 ± 0.01	2.696LysIle: 2.696 ± 0.016	4.579LysLys: 4.579 ± 0.026	5.097LysLeu: 5.097 ± 0.023	1.412LysMet: 1.412 ± 0.012	2.312LysAsn: 2.312 ± 0.013	3.08LysPro: 3.08 ± 0.02	2.532LysGln: 2.532 ± 0.015	3.242LysArg: 3.242 ± 0.014	3.873LysSer: 3.873 ± 0.023	3.055LysThr: 3.055 ± 0.015	3.425LysVal: 3.425 ± 0.02	0.591LysTrp: 0.591 ± 0.006	1.538LysTyr: 1.538 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	6.96LeuAla: 6.96 ± 0.026	2.215LeuCys: 2.215 ± 0.012	4.767LeuAsp: 4.767 ± 0.019	7.172LeuGlu: 7.172 ± 0.034	3.455LeuPhe: 3.455 ± 0.017	5.998LeuGly: 5.998 ± 0.021	2.726LeuHis: 2.726 ± 0.014	3.864LeuIle: 3.864 ± 0.018	5.744LeuLys: 5.744 ± 0.024	10.97LeuLeu: 10.97 ± 0.046	1.981LeuMet: 1.981 ± 0.011	3.5LeuAsn: 3.5 ± 0.016	6.053LeuPro: 6.053 ± 0.027	5.837LeuGln: 5.837 ± 0.028	6.063LeuArg: 6.063 ± 0.025	8.137LeuSer: 8.137 ± 0.025	5.129LeuThr: 5.129 ± 0.018	5.592LeuVal: 5.592 ± 0.022	1.148LeuTrp: 1.148 ± 0.008	2.56LeuTyr: 2.56 ± 0.015	0.0LeuXaa: 0.0 ± 0.0
Met	1.864MetAla: 1.864 ± 0.01	0.381MetCys: 0.381 ± 0.005	1.234MetAsp: 1.234 ± 0.009	1.781MetGlu: 1.781 ± 0.011	0.727MetPhe: 0.727 ± 0.007	1.257MetGly: 1.257 ± 0.01	0.43MetHis: 0.43 ± 0.005	0.825MetIle: 0.825 ± 0.008	1.422MetLys: 1.422 ± 0.01	1.925MetLeu: 1.925 ± 0.01	0.544MetMet: 0.544 ± 0.006	0.859MetAsn: 0.859 ± 0.007	1.066MetPro: 1.066 ± 0.016	0.882MetGln: 0.882 ± 0.008	1.003MetArg: 1.003 ± 0.007	1.532MetSer: 1.532 ± 0.01	1.089MetThr: 1.089 ± 0.009	1.367MetVal: 1.367 ± 0.009	0.231MetTrp: 0.231 ± 0.004	0.587MetTyr: 0.587 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.019AsnAla: 2.019 ± 0.011	0.834AsnCys: 0.834 ± 0.008	1.467AsnAsp: 1.467 ± 0.011	2.143AsnGlu: 2.143 ± 0.012	1.453AsnPhe: 1.453 ± 0.011	2.429AsnGly: 2.429 ± 0.014	0.923AsnHis: 0.923 ± 0.007	2.061AsnIle: 2.061 ± 0.013	2.115AsnLys: 2.115 ± 0.012	3.697AsnLeu: 3.697 ± 0.015	0.865AsnMet: 0.865 ± 0.008	1.446AsnAsn: 1.446 ± 0.011	2.155AsnPro: 2.155 ± 0.013	1.612AsnGln: 1.612 ± 0.01	1.801AsnArg: 1.801 ± 0.01	3.014AsnSer: 3.014 ± 0.017	1.888AsnThr: 1.888 ± 0.012	2.147AsnVal: 2.147 ± 0.012	0.445AsnTrp: 0.445 ± 0.005	1.094AsnTyr: 1.094 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	5.179ProAla: 5.179 ± 0.036	1.199ProCys: 1.199 ± 0.014	2.822ProAsp: 2.822 ± 0.019	4.541ProGlu: 4.541 ± 0.024	1.94ProPhe: 1.94 ± 0.011	5.352ProGly: 5.352 ± 0.044	1.47ProHis: 1.47 ± 0.01	1.8ProIle: 1.8 ± 0.011	2.789ProLys: 2.789 ± 0.029	5.354ProLeu: 5.354 ± 0.024	1.042ProMet: 1.042 ± 0.009	1.768ProAsn: 1.768 ± 0.01	6.34ProPro: 6.34 ± 0.057	2.869ProGln: 2.869 ± 0.02	3.503ProArg: 3.503 ± 0.02	5.852ProSer: 5.852 ± 0.029	3.069ProThr: 3.069 ± 0.017	3.85ProVal: 3.85 ± 0.019	0.707ProTrp: 0.707 ± 0.007	1.492ProTyr: 1.492 ± 0.013	0.0ProXaa: 0.0 ± 0.0
Gln	3.55GlnAla: 3.55 ± 0.017	0.94GlnCys: 0.94 ± 0.009	2.319GlnAsp: 2.319 ± 0.013	3.933GlnGlu: 3.933 ± 0.022	1.361GlnPhe: 1.361 ± 0.01	2.835GlnGly: 2.835 ± 0.015	1.283GlnHis: 1.283 ± 0.009	1.934GlnIle: 1.934 ± 0.01	2.88GlnLys: 2.88 ± 0.016	4.759GlnLeu: 4.759 ± 0.024	1.083GlnMet: 1.083 ± 0.008	1.8GlnAsn: 1.8 ± 0.011	2.827GlnPro: 2.827 ± 0.021	2.976GlnGln: 2.976 ± 0.027	3.015GlnArg: 3.015 ± 0.015	3.11GlnSer: 3.11 ± 0.017	2.307GlnThr: 2.307 ± 0.012	2.829GlnVal: 2.829 ± 0.013	0.529GlnTrp: 0.529 ± 0.006	1.111GlnTyr: 1.111 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	4.039ArgAla: 4.039 ± 0.019	1.254ArgCys: 1.254 ± 0.012	2.773ArgAsp: 2.773 ± 0.014	4.049ArgGlu: 4.049 ± 0.019	1.872ArgPhe: 1.872 ± 0.011	3.723ArgGly: 3.723 ± 0.021	1.537ArgHis: 1.537 ± 0.011	2.405ArgIle: 2.405 ± 0.012	3.644ArgLys: 3.644 ± 0.016	5.558ArgLeu: 5.558 ± 0.024	1.16ArgMet: 1.16 ± 0.008	2.098ArgAsn: 2.098 ± 0.011	3.369ArgPro: 3.369 ± 0.019	2.64ArgGln: 2.64 ± 0.014	4.462ArgArg: 4.462 ± 0.026	4.41ArgSer: 4.41 ± 0.028	2.818ArgThr: 2.818 ± 0.014	3.204ArgVal: 3.204 ± 0.014	0.722ArgTrp: 0.722 ± 0.007	1.491ArgTyr: 1.491 ± 0.009	0.0ArgXaa: 0.0 ± 0.0
Ser	5.485SerAla: 5.485 ± 0.022	1.888SerCys: 1.888 ± 0.019	3.912SerAsp: 3.912 ± 0.021	5.251SerGlu: 5.251 ± 0.022	3.086SerPhe: 3.086 ± 0.014	5.712SerGly: 5.712 ± 0.025	2.141SerHis: 2.141 ± 0.013	3.213SerIle: 3.213 ± 0.015	4.042SerLys: 4.042 ± 0.022	8.345SerLeu: 8.345 ± 0.026	1.554SerMet: 1.554 ± 0.012	2.603SerAsn: 2.603 ± 0.015	6.148SerPro: 6.148 ± 0.035	3.855SerGln: 3.855 ± 0.017	4.704SerArg: 4.704 ± 0.026	9.296SerSer: 9.296 ± 0.044	4.351SerThr: 4.351 ± 0.018	4.977SerVal: 4.977 ± 0.019	1.068SerTrp: 1.068 ± 0.009	2.09SerTyr: 2.09 ± 0.012	0.0SerXaa: 0.0 ± 0.0
Thr	3.772ThrAla: 3.772 ± 0.017	1.317ThrCys: 1.317 ± 0.015	2.462ThrAsp: 2.462 ± 0.012	3.481ThrGlu: 3.481 ± 0.016	2.098ThrPhe: 2.098 ± 0.011	3.532ThrGly: 3.532 ± 0.019	1.284ThrHis: 1.284 ± 0.01	2.309ThrIle: 2.309 ± 0.012	2.548ThrLys: 2.548 ± 0.014	5.332ThrLeu: 5.332 ± 0.016	1.068ThrMet: 1.068 ± 0.007	1.65ThrAsn: 1.65 ± 0.012	3.566ThrPro: 3.566 ± 0.021	2.25ThrGln: 2.25 ± 0.012	2.456ThrArg: 2.456 ± 0.011	4.498ThrSer: 4.498 ± 0.02	2.819ThrThr: 2.819 ± 0.018	3.924ThrVal: 3.924 ± 0.016	0.679ThrTrp: 0.679 ± 0.007	1.408ThrTyr: 1.408 ± 0.009	0.0ThrXaa: 0.0 ± 0.0
Val	4.273ValAla: 4.273 ± 0.017	1.492ValCys: 1.492 ± 0.011	2.997ValAsp: 2.997 ± 0.02	3.839ValGlu: 3.839 ± 0.015	2.467ValPhe: 2.467 ± 0.014	3.401ValGly: 3.401 ± 0.015	1.564ValHis: 1.564 ± 0.012	2.917ValIle: 2.917 ± 0.015	3.377ValLys: 3.377 ± 0.018	6.315ValLeu: 6.315 ± 0.023	1.316ValMet: 1.316 ± 0.009	2.239ValAsn: 2.239 ± 0.014	3.663ValPro: 3.663 ± 0.016	2.722ValGln: 2.722 ± 0.014	3.093ValArg: 3.093 ± 0.014	5.0ValSer: 5.0 ± 0.018	3.77ValThr: 3.77 ± 0.018	4.021ValVal: 4.021 ± 0.017	0.718ValTrp: 0.718 ± 0.007	1.638ValTyr: 1.638 ± 0.009	0.0ValXaa: 0.0 ± 0.0
Trp	0.816TrpAla: 0.816 ± 0.009	0.247TrpCys: 0.247 ± 0.004	0.657TrpAsp: 0.657 ± 0.008	0.799TrpGlu: 0.799 ± 0.008	0.444TrpPhe: 0.444 ± 0.005	0.762TrpGly: 0.762 ± 0.008	0.302TrpHis: 0.302 ± 0.004	0.548TrpIle: 0.548 ± 0.006	0.793TrpLys: 0.793 ± 0.006	1.218TrpLeu: 1.218 ± 0.01	0.301TrpMet: 0.301 ± 0.004	0.522TrpAsn: 0.522 ± 0.005	0.52TrpPro: 0.52 ± 0.005	0.527TrpGln: 0.527 ± 0.005	0.759TrpArg: 0.759 ± 0.007	0.879TrpSer: 0.879 ± 0.008	0.669TrpThr: 0.669 ± 0.007	0.709TrpVal: 0.709 ± 0.006	0.194TrpTrp: 0.194 ± 0.004	0.327TrpTyr: 0.327 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.395TyrAla: 1.395 ± 0.009	0.669TyrCys: 0.669 ± 0.006	1.295TyrAsp: 1.295 ± 0.009	1.675TyrGlu: 1.675 ± 0.01	1.254TyrPhe: 1.254 ± 0.009	1.696TyrGly: 1.696 ± 0.012	0.735TyrHis: 0.735 ± 0.007	1.323TyrIle: 1.323 ± 0.009	1.458TyrLys: 1.458 ± 0.014	2.645TyrLeu: 2.645 ± 0.014	0.6TyrMet: 0.6 ± 0.006	1.069TyrAsn: 1.069 ± 0.009	1.286TyrPro: 1.286 ± 0.009	1.235TyrGln: 1.235 ± 0.009	1.608TyrArg: 1.608 ± 0.012	2.22TyrSer: 2.22 ± 0.011	1.5TyrThr: 1.5 ± 0.01	1.575TyrVal: 1.575 ± 0.01	0.365TyrTrp: 0.365 ± 0.006	0.941TyrTyr: 0.941 ± 0.007	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 32615 proteins (19787655 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---