Amino acid dipepetide frequency for Trichoplusia ni (Cabbage looper)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.421AlaAla: 8.421 ± 0.085	1.373AlaCys: 1.373 ± 0.024	3.644AlaAsp: 3.644 ± 0.021	4.77AlaGlu: 4.77 ± 0.032	2.16AlaPhe: 2.16 ± 0.017	4.661AlaGly: 4.661 ± 0.041	1.827AlaHis: 1.827 ± 0.016	3.16AlaIle: 3.16 ± 0.023	3.843AlaLys: 3.843 ± 0.028	6.951AlaLeu: 6.951 ± 0.048	1.516AlaMet: 1.516 ± 0.013	2.595AlaAsn: 2.595 ± 0.019	4.829AlaPro: 4.829 ± 0.037	2.87AlaGln: 2.87 ± 0.021	4.491AlaArg: 4.491 ± 0.032	5.345AlaSer: 5.345 ± 0.033	4.139AlaThr: 4.139 ± 0.03	4.763AlaVal: 4.763 ± 0.03	0.736AlaTrp: 0.736 ± 0.01	1.801AlaTyr: 1.801 ± 0.015	0.002AlaXaa: 0.002 ± 0.0
Cys	1.349CysAla: 1.349 ± 0.015	0.465CysCys: 0.465 ± 0.008	1.13CysAsp: 1.13 ± 0.016	1.13CysGlu: 1.13 ± 0.014	0.686CysPhe: 0.686 ± 0.014	1.348CysGly: 1.348 ± 0.025	0.463CysHis: 0.463 ± 0.007	0.912CysIle: 0.912 ± 0.017	1.031CysLys: 1.031 ± 0.015	1.639CysLeu: 1.639 ± 0.021	0.362CysMet: 0.362 ± 0.006	0.824CysAsn: 0.824 ± 0.014	1.057CysPro: 1.057 ± 0.029	0.684CysGln: 0.684 ± 0.013	1.12CysArg: 1.12 ± 0.023	1.458CysSer: 1.458 ± 0.023	1.02CysThr: 1.02 ± 0.019	1.334CysVal: 1.334 ± 0.022	0.211CysTrp: 0.211 ± 0.004	0.564CysTyr: 0.564 ± 0.011	0.001CysXaa: 0.001 ± 0.0
Asp	3.787AspAla: 3.787 ± 0.027	0.965AspCys: 0.965 ± 0.014	4.164AspAsp: 4.164 ± 0.04	4.519AspGlu: 4.519 ± 0.035	1.987AspPhe: 1.987 ± 0.017	3.168AspGly: 3.168 ± 0.024	1.197AspHis: 1.197 ± 0.01	3.192AspIle: 3.192 ± 0.019	3.639AspLys: 3.639 ± 0.03	4.787AspLeu: 4.787 ± 0.027	1.29AspMet: 1.29 ± 0.01	2.63AspAsn: 2.63 ± 0.022	2.695AspPro: 2.695 ± 0.034	1.686AspGln: 1.686 ± 0.012	2.755AspArg: 2.755 ± 0.026	4.453AspSer: 4.453 ± 0.03	3.211AspThr: 3.211 ± 0.026	3.767AspVal: 3.767 ± 0.025	0.625AspTrp: 0.625 ± 0.009	1.765AspTyr: 1.765 ± 0.015	0.001AspXaa: 0.001 ± 0.0
Glu	4.847GluAla: 4.847 ± 0.033	1.193GluCys: 1.193 ± 0.027	4.155GluAsp: 4.155 ± 0.029	6.116GluGlu: 6.116 ± 0.066	1.981GluPhe: 1.981 ± 0.014	3.39GluGly: 3.39 ± 0.033	1.545GluHis: 1.545 ± 0.013	3.675GluIle: 3.675 ± 0.043	5.053GluLys: 5.053 ± 0.064	6.03GluLeu: 6.03 ± 0.041	1.513GluMet: 1.513 ± 0.014	3.346GluAsn: 3.346 ± 0.021	3.364GluPro: 3.364 ± 0.036	3.087GluGln: 3.087 ± 0.056	4.241GluArg: 4.241 ± 0.034	4.723GluSer: 4.723 ± 0.037	3.93GluThr: 3.93 ± 0.045	4.114GluVal: 4.114 ± 0.029	0.739GluTrp: 0.739 ± 0.011	1.978GluTyr: 1.978 ± 0.016	0.001GluXaa: 0.001 ± 0.0
Phe	2.056PheAla: 2.056 ± 0.016	0.675PheCys: 0.675 ± 0.008	1.957PheAsp: 1.957 ± 0.015	2.004PheGlu: 2.004 ± 0.017	1.277PhePhe: 1.277 ± 0.015	2.115PheGly: 2.115 ± 0.019	0.818PheHis: 0.818 ± 0.009	1.859PheIle: 1.859 ± 0.016	1.966PheLys: 1.966 ± 0.015	2.995PheLeu: 2.995 ± 0.022	0.782PheMet: 0.782 ± 0.009	1.642PheAsn: 1.642 ± 0.013	1.491PhePro: 1.491 ± 0.014	1.215PheGln: 1.215 ± 0.011	1.816PheArg: 1.816 ± 0.016	2.497PheSer: 2.497 ± 0.014	1.991PheThr: 1.991 ± 0.015	2.214PheVal: 2.214 ± 0.016	0.379PheTrp: 0.379 ± 0.006	1.184PheTyr: 1.184 ± 0.013	0.001PheXaa: 0.001 ± 0.0
Gly	4.649GlyAla: 4.649 ± 0.044	1.002GlyCys: 1.002 ± 0.018	3.039GlyAsp: 3.039 ± 0.022	3.432GlyGlu: 3.432 ± 0.028	1.998GlyPhe: 1.998 ± 0.017	4.944GlyGly: 4.944 ± 0.053	1.406GlyHis: 1.406 ± 0.017	2.515GlyIle: 2.515 ± 0.019	3.192GlyLys: 3.192 ± 0.028	4.457GlyLeu: 4.457 ± 0.029	1.138GlyMet: 1.138 ± 0.012	2.356GlyAsn: 2.356 ± 0.018	2.924GlyPro: 2.924 ± 0.041	2.196GlyGln: 2.196 ± 0.065	3.155GlyArg: 3.155 ± 0.029	4.829GlySer: 4.829 ± 0.041	3.065GlyThr: 3.065 ± 0.021	3.635GlyVal: 3.635 ± 0.025	0.686GlyTrp: 0.686 ± 0.01	1.934GlyTyr: 1.934 ± 0.024	0.003GlyXaa: 0.003 ± 0.0
His	1.822HisAla: 1.822 ± 0.019	0.534HisCys: 0.534 ± 0.008	1.277HisAsp: 1.277 ± 0.012	1.443HisGlu: 1.443 ± 0.013	0.917HisPhe: 0.917 ± 0.01	1.334HisGly: 1.334 ± 0.012	1.086HisHis: 1.086 ± 0.02	1.282HisIle: 1.282 ± 0.011	1.417HisLys: 1.417 ± 0.013	2.217HisLeu: 2.217 ± 0.016	0.619HisMet: 0.619 ± 0.007	1.144HisAsn: 1.144 ± 0.012	1.403HisPro: 1.403 ± 0.014	1.045HisGln: 1.045 ± 0.011	1.429HisArg: 1.429 ± 0.012	1.919HisSer: 1.919 ± 0.017	1.496HisThr: 1.496 ± 0.016	1.52HisVal: 1.52 ± 0.011	0.286HisTrp: 0.286 ± 0.005	0.904HisTyr: 0.904 ± 0.008	0.001HisXaa: 0.001 ± 0.0
Ile	3.231IleAla: 3.231 ± 0.018	1.02IleCys: 1.02 ± 0.016	2.958IleAsp: 2.958 ± 0.021	3.432IleGlu: 3.432 ± 0.033	1.801IlePhe: 1.801 ± 0.018	2.446IleGly: 2.446 ± 0.019	1.178IleHis: 1.178 ± 0.011	2.906IleIle: 2.906 ± 0.023	3.5IleLys: 3.5 ± 0.031	4.276IleLeu: 4.276 ± 0.024	1.084IleMet: 1.084 ± 0.011	2.492IleAsn: 2.492 ± 0.018	2.577IlePro: 2.577 ± 0.017	2.069IleGln: 2.069 ± 0.017	2.483IleArg: 2.483 ± 0.015	3.749IleSer: 3.749 ± 0.022	3.245IleThr: 3.245 ± 0.032	3.315IleVal: 3.315 ± 0.023	0.438IleTrp: 0.438 ± 0.006	1.495IleTyr: 1.495 ± 0.013	0.001IleXaa: 0.001 ± 0.0
Lys	3.735LysAla: 3.735 ± 0.032	1.165LysCys: 1.165 ± 0.02	3.784LysAsp: 3.784 ± 0.037	4.925LysGlu: 4.925 ± 0.052	1.938LysPhe: 1.938 ± 0.015	2.672LysGly: 2.672 ± 0.022	1.582LysHis: 1.582 ± 0.016	3.399LysIle: 3.399 ± 0.028	5.558LysLys: 5.558 ± 0.075	5.464LysLeu: 5.464 ± 0.034	1.479LysMet: 1.479 ± 0.013	3.033LysAsn: 3.033 ± 0.023	3.75LysPro: 3.75 ± 0.059	2.673LysGln: 2.673 ± 0.023	3.688LysArg: 3.688 ± 0.026	4.462LysSer: 4.462 ± 0.03	3.747LysThr: 3.747 ± 0.035	3.755LysVal: 3.755 ± 0.032	0.633LysTrp: 0.633 ± 0.012	2.083LysTyr: 2.083 ± 0.018	0.003LysXaa: 0.003 ± 0.001
Leu	6.71LeuAla: 6.71 ± 0.041	1.733LeuCys: 1.733 ± 0.014	4.811LeuAsp: 4.811 ± 0.03	6.039LeuGlu: 6.039 ± 0.043	2.871LeuPhe: 2.871 ± 0.025	4.366LeuGly: 4.366 ± 0.028	2.312LeuHis: 2.312 ± 0.016	3.954LeuIle: 3.954 ± 0.023	5.707LeuLys: 5.707 ± 0.038	8.462LeuLeu: 8.462 ± 0.051	1.89LeuMet: 1.89 ± 0.015	3.951LeuAsn: 3.951 ± 0.023	4.854LeuPro: 4.854 ± 0.033	4.304LeuGln: 4.304 ± 0.026	5.486LeuArg: 5.486 ± 0.033	6.642LeuSer: 6.642 ± 0.031	4.945LeuThr: 4.945 ± 0.026	5.244LeuVal: 5.244 ± 0.03	0.858LeuTrp: 0.858 ± 0.011	2.469LeuTyr: 2.469 ± 0.019	0.002LeuXaa: 0.002 ± 0.0
Met	1.572MetAla: 1.572 ± 0.012	0.431MetCys: 0.431 ± 0.007	1.255MetAsp: 1.255 ± 0.011	1.561MetGlu: 1.561 ± 0.012	0.853MetPhe: 0.853 ± 0.011	1.135MetGly: 1.135 ± 0.018	0.514MetHis: 0.514 ± 0.007	0.946MetIle: 0.946 ± 0.009	1.389MetLys: 1.389 ± 0.012	1.924MetLeu: 1.924 ± 0.017	0.612MetMet: 0.612 ± 0.009	0.988MetAsn: 0.988 ± 0.011	1.123MetPro: 1.123 ± 0.012	0.955MetGln: 0.955 ± 0.012	1.192MetArg: 1.192 ± 0.012	1.814MetSer: 1.814 ± 0.013	1.208MetThr: 1.208 ± 0.01	1.229MetVal: 1.229 ± 0.011	0.25MetTrp: 0.25 ± 0.005	0.701MetTyr: 0.701 ± 0.008	0.001MetXaa: 0.001 ± 0.0
Asn	2.797AsnAla: 2.797 ± 0.022	0.81AsnCys: 0.81 ± 0.013	2.462AsnAsp: 2.462 ± 0.018	2.992AsnGlu: 2.992 ± 0.019	1.619AsnPhe: 1.619 ± 0.013	2.647AsnGly: 2.647 ± 0.023	0.984AsnHis: 0.984 ± 0.012	2.883AsnIle: 2.883 ± 0.018	3.093AsnLys: 3.093 ± 0.023	3.923AsnLeu: 3.923 ± 0.024	1.153AsnMet: 1.153 ± 0.011	2.755AsnAsn: 2.755 ± 0.025	2.112AsnPro: 2.112 ± 0.025	1.728AsnGln: 1.728 ± 0.016	2.125AsnArg: 2.125 ± 0.017	3.506AsnSer: 3.506 ± 0.028	2.685AsnThr: 2.685 ± 0.019	3.083AsnVal: 3.083 ± 0.02	0.432AsnTrp: 0.432 ± 0.006	1.51AsnTyr: 1.51 ± 0.016	0.001AsnXaa: 0.001 ± 0.0
Pro	4.941ProAla: 4.941 ± 0.039	0.802ProCys: 0.802 ± 0.03	3.009ProAsp: 3.009 ± 0.02	3.98ProGlu: 3.98 ± 0.043	1.53ProPhe: 1.53 ± 0.014	3.455ProGly: 3.455 ± 0.115	1.557ProHis: 1.557 ± 0.017	2.451ProIle: 2.451 ± 0.022	3.675ProLys: 3.675 ± 0.079	4.403ProLeu: 4.403 ± 0.027	1.053ProMet: 1.053 ± 0.012	2.265ProAsn: 2.265 ± 0.021	5.603ProPro: 5.603 ± 0.062	2.36ProGln: 2.36 ± 0.02	3.2ProArg: 3.2 ± 0.036	4.607ProSer: 4.607 ± 0.044	3.654ProThr: 3.654 ± 0.045	3.669ProVal: 3.669 ± 0.032	0.473ProTrp: 0.473 ± 0.007	1.558ProTyr: 1.558 ± 0.018	0.003ProXaa: 0.003 ± 0.001
Gln	2.831GlnAla: 2.831 ± 0.02	0.75GlnCys: 0.75 ± 0.015	1.926GlnAsp: 1.926 ± 0.013	2.797GlnGlu: 2.797 ± 0.031	1.29GlnPhe: 1.29 ± 0.01	2.004GlnGly: 2.004 ± 0.03	1.217GlnHis: 1.217 ± 0.014	2.027GlnIle: 2.027 ± 0.013	2.458GlnLys: 2.458 ± 0.024	3.891GlnLeu: 3.891 ± 0.027	0.986GlnMet: 0.986 ± 0.012	1.959GlnAsn: 1.959 ± 0.017	2.947GlnPro: 2.947 ± 0.082	2.88GlnGln: 2.88 ± 0.059	2.5GlnArg: 2.5 ± 0.023	2.756GlnSer: 2.756 ± 0.019	2.187GlnThr: 2.187 ± 0.018	2.403GlnVal: 2.403 ± 0.02	0.458GlnTrp: 0.458 ± 0.007	1.293GlnTyr: 1.293 ± 0.013	0.001GlnXaa: 0.001 ± 0.0
Arg	4.563ArgAla: 4.563 ± 0.037	1.151ArgCys: 1.151 ± 0.03	3.203ArgAsp: 3.203 ± 0.025	3.674ArgGlu: 3.674 ± 0.029	1.764ArgPhe: 1.764 ± 0.013	3.128ArgGly: 3.128 ± 0.031	1.608ArgHis: 1.608 ± 0.015	2.531ArgIle: 2.531 ± 0.015	3.57ArgLys: 3.57 ± 0.023	5.193ArgLeu: 5.193 ± 0.034	1.142ArgMet: 1.142 ± 0.01	2.473ArgAsn: 2.473 ± 0.018	3.156ArgPro: 3.156 ± 0.029	2.347ArgGln: 2.347 ± 0.019	4.811ArgArg: 4.811 ± 0.037	4.309ArgSer: 4.309 ± 0.028	2.909ArgThr: 2.909 ± 0.02	3.414ArgVal: 3.414 ± 0.022	0.689ArgTrp: 0.689 ± 0.008	1.692ArgTyr: 1.692 ± 0.015	0.002ArgXaa: 0.002 ± 0.0
Ser	5.294SerAla: 5.294 ± 0.033	1.361SerCys: 1.361 ± 0.023	4.499SerAsp: 4.499 ± 0.027	5.151SerGlu: 5.151 ± 0.029	2.428SerPhe: 2.428 ± 0.017	4.819SerGly: 4.819 ± 0.036	1.773SerHis: 1.773 ± 0.015	3.535SerIle: 3.535 ± 0.021	4.401SerLys: 4.401 ± 0.028	6.558SerLeu: 6.558 ± 0.035	1.561SerMet: 1.561 ± 0.012	3.432SerAsn: 3.432 ± 0.028	4.891SerPro: 4.891 ± 0.046	2.985SerGln: 2.985 ± 0.022	4.214SerArg: 4.214 ± 0.028	8.056SerSer: 8.056 ± 0.08	5.255SerThr: 5.255 ± 0.074	4.733SerVal: 4.733 ± 0.023	0.786SerTrp: 0.786 ± 0.008	2.088SerTyr: 2.088 ± 0.017	0.002SerXaa: 0.002 ± 0.0
Thr	4.176ThrAla: 4.176 ± 0.024	1.106ThrCys: 1.106 ± 0.018	3.19ThrAsp: 3.19 ± 0.023	4.231ThrGlu: 4.231 ± 0.07	2.01ThrPhe: 2.01 ± 0.014	3.289ThrGly: 3.289 ± 0.027	1.44ThrHis: 1.44 ± 0.015	3.093ThrIle: 3.093 ± 0.024	3.572ThrLys: 3.572 ± 0.033	5.112ThrLeu: 5.112 ± 0.025	1.154ThrMet: 1.154 ± 0.01	2.553ThrAsn: 2.553 ± 0.018	4.056ThrPro: 4.056 ± 0.034	2.335ThrGln: 2.335 ± 0.025	2.728ThrArg: 2.728 ± 0.018	4.915ThrSer: 4.915 ± 0.038	5.473ThrThr: 5.473 ± 0.169	4.118ThrVal: 4.118 ± 0.049	0.598ThrTrp: 0.598 ± 0.009	1.663ThrTyr: 1.663 ± 0.015	0.001ThrXaa: 0.001 ± 0.0
Val	4.651ValAla: 4.651 ± 0.03	1.35ValCys: 1.35 ± 0.02	3.482ValAsp: 3.482 ± 0.026	4.259ValGlu: 4.259 ± 0.045	2.208ValPhe: 2.208 ± 0.019	3.206ValGly: 3.206 ± 0.022	1.519ValHis: 1.519 ± 0.012	3.326ValIle: 3.326 ± 0.026	4.008ValLys: 4.008 ± 0.038	5.598ValLeu: 5.598 ± 0.031	1.364ValMet: 1.364 ± 0.011	2.831ValAsn: 2.831 ± 0.02	3.523ValPro: 3.523 ± 0.023	2.519ValGln: 2.519 ± 0.018	3.402ValArg: 3.402 ± 0.022	4.766ValSer: 4.766 ± 0.022	4.306ValThr: 4.306 ± 0.049	4.366ValVal: 4.366 ± 0.028	0.687ValTrp: 0.687 ± 0.01	1.863ValTyr: 1.863 ± 0.014	0.001ValXaa: 0.001 ± 0.0
Trp	0.662TrpAla: 0.662 ± 0.008	0.23TrpCys: 0.23 ± 0.005	0.591TrpAsp: 0.591 ± 0.007	0.656TrpGlu: 0.656 ± 0.009	0.412TrpPhe: 0.412 ± 0.007	0.557TrpGly: 0.557 ± 0.01	0.246TrpHis: 0.246 ± 0.005	0.51TrpIle: 0.51 ± 0.008	0.619TrpLys: 0.619 ± 0.01	1.089TrpLeu: 1.089 ± 0.013	0.266TrpMet: 0.266 ± 0.005	0.482TrpAsn: 0.482 ± 0.007	0.44TrpPro: 0.44 ± 0.007	0.424TrpGln: 0.424 ± 0.006	0.778TrpArg: 0.778 ± 0.011	0.784TrpSer: 0.784 ± 0.009	0.575TrpThr: 0.575 ± 0.009	0.637TrpVal: 0.637 ± 0.007	0.204TrpTrp: 0.204 ± 0.004	0.355TrpTyr: 0.355 ± 0.006	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.8TyrAla: 1.8 ± 0.015	0.67TyrCys: 0.67 ± 0.009	1.747TyrAsp: 1.747 ± 0.015	1.91TyrGlu: 1.91 ± 0.015	1.203TyrPhe: 1.203 ± 0.012	1.865TyrGly: 1.865 ± 0.021	0.822TyrHis: 0.822 ± 0.009	1.535TyrIle: 1.535 ± 0.014	1.834TyrLys: 1.834 ± 0.016	2.64TyrLeu: 2.64 ± 0.021	0.689TyrMet: 0.689 ± 0.008	1.55TyrAsn: 1.55 ± 0.014	1.45TyrPro: 1.45 ± 0.025	1.198TyrGln: 1.198 ± 0.011	1.712TyrArg: 1.712 ± 0.013	2.233TyrSer: 2.233 ± 0.017	1.769TyrThr: 1.769 ± 0.015	1.922TyrVal: 1.922 ± 0.015	0.35TyrTrp: 0.35 ± 0.006	1.186TyrTyr: 1.186 ± 0.013	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.003XaaGly: 0.003 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.002XaaIle: 0.002 ± 0.001	0.002XaaLys: 0.002 ± 0.0	0.003XaaLeu: 0.003 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.002XaaSer: 0.002 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 20889 proteins (13497636 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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