Amino acid dipepetide frequency for Nesidiocoris tenuis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.72AlaAla: 5.72 ± 0.043	1.132AlaCys: 1.132 ± 0.015	3.285AlaAsp: 3.285 ± 0.022	3.867AlaGlu: 3.867 ± 0.033	2.226AlaPhe: 2.226 ± 0.019	3.853AlaGly: 3.853 ± 0.032	1.441AlaHis: 1.441 ± 0.017	3.256AlaIle: 3.256 ± 0.023	3.546AlaLys: 3.546 ± 0.027	5.425AlaLeu: 5.425 ± 0.034	1.399AlaMet: 1.399 ± 0.017	2.463AlaAsn: 2.463 ± 0.02	3.678AlaPro: 3.678 ± 0.035	2.422AlaGln: 2.422 ± 0.021	3.974AlaArg: 3.974 ± 0.029	5.473AlaSer: 5.473 ± 0.033	3.673AlaThr: 3.673 ± 0.026	4.252AlaVal: 4.252 ± 0.028	0.66AlaTrp: 0.66 ± 0.01	1.623AlaTyr: 1.623 ± 0.02	0.003AlaXaa: 0.003 ± 0.001
Cys	1.161CysAla: 1.161 ± 0.014	0.546CysCys: 0.546 ± 0.013	1.008CysAsp: 1.008 ± 0.016	1.051CysGlu: 1.051 ± 0.015	0.826CysPhe: 0.826 ± 0.01	1.324CysGly: 1.324 ± 0.018	0.581CysHis: 0.581 ± 0.009	0.909CysIle: 0.909 ± 0.013	0.963CysLys: 0.963 ± 0.015	1.784CysLeu: 1.784 ± 0.02	0.35CysMet: 0.35 ± 0.008	0.775CysAsn: 0.775 ± 0.013	1.265CysPro: 1.265 ± 0.02	0.858CysGln: 0.858 ± 0.014	1.531CysArg: 1.531 ± 0.022	1.882CysSer: 1.882 ± 0.02	1.083CysThr: 1.083 ± 0.014	1.156CysVal: 1.156 ± 0.016	0.297CysTrp: 0.297 ± 0.006	0.576CysTyr: 0.576 ± 0.009	0.001CysXaa: 0.001 ± 0.0
Asp	2.906AspAla: 2.906 ± 0.021	0.954AspCys: 0.954 ± 0.015	3.447AspAsp: 3.447 ± 0.029	3.532AspGlu: 3.532 ± 0.03	2.308AspPhe: 2.308 ± 0.022	3.105AspGly: 3.105 ± 0.026	1.175AspHis: 1.175 ± 0.015	2.424AspIle: 2.424 ± 0.021	2.329AspLys: 2.329 ± 0.02	4.27AspLeu: 4.27 ± 0.03	0.958AspMet: 0.958 ± 0.013	1.869AspAsn: 1.869 ± 0.019	2.529AspPro: 2.529 ± 0.027	2.525AspGln: 2.525 ± 0.043	3.11AspArg: 3.11 ± 0.025	3.996AspSer: 3.996 ± 0.031	2.163AspThr: 2.163 ± 0.018	3.231AspVal: 3.231 ± 0.023	0.615AspTrp: 0.615 ± 0.009	1.449AspTyr: 1.449 ± 0.016	0.003AspXaa: 0.003 ± 0.001
Glu	3.69GluAla: 3.69 ± 0.032	0.996GluCys: 0.996 ± 0.018	3.194GluAsp: 3.194 ± 0.026	5.036GluGlu: 5.036 ± 0.055	2.929GluPhe: 2.929 ± 0.042	3.012GluGly: 3.012 ± 0.025	1.245GluHis: 1.245 ± 0.014	4.91GluIle: 4.91 ± 0.068	4.169GluLys: 4.169 ± 0.038	5.113GluLeu: 5.113 ± 0.038	1.438GluMet: 1.438 ± 0.016	2.831GluAsn: 2.831 ± 0.022	2.669GluPro: 2.669 ± 0.026	2.091GluGln: 2.091 ± 0.023	3.737GluArg: 3.737 ± 0.028	4.237GluSer: 4.237 ± 0.036	3.242GluThr: 3.242 ± 0.029	3.384GluVal: 3.384 ± 0.026	0.588GluTrp: 0.588 ± 0.011	1.488GluTyr: 1.488 ± 0.017	0.009GluXaa: 0.009 ± 0.001
Phe	2.211PheAla: 2.211 ± 0.019	0.956PheCys: 0.956 ± 0.01	2.284PheAsp: 2.284 ± 0.031	4.575PheGlu: 4.575 ± 0.095	1.754PhePhe: 1.754 ± 0.017	2.426PheGly: 2.426 ± 0.022	1.16PheHis: 1.16 ± 0.014	1.891PheIle: 1.891 ± 0.016	2.773PheLys: 2.773 ± 0.037	3.787PheLeu: 3.787 ± 0.026	0.776PheMet: 0.776 ± 0.011	1.716PheAsn: 1.716 ± 0.02	1.953PhePro: 1.953 ± 0.018	1.7PheGln: 1.7 ± 0.017	2.583PheArg: 2.583 ± 0.024	3.415PheSer: 3.415 ± 0.027	2.087PheThr: 2.087 ± 0.017	2.374PheVal: 2.374 ± 0.021	0.531PheTrp: 0.531 ± 0.008	1.165PheTyr: 1.165 ± 0.016	0.005PheXaa: 0.005 ± 0.001
Gly	3.65GlyAla: 3.65 ± 0.029	1.108GlyCys: 1.108 ± 0.015	2.71GlyAsp: 2.71 ± 0.025	3.097GlyGlu: 3.097 ± 0.026	2.091GlyPhe: 2.091 ± 0.018	4.797GlyGly: 4.797 ± 0.06	1.642GlyHis: 1.642 ± 0.023	2.795GlyIle: 2.795 ± 0.024	3.143GlyLys: 3.143 ± 0.026	4.477GlyLeu: 4.477 ± 0.026	1.153GlyMet: 1.153 ± 0.015	2.349GlyAsn: 2.349 ± 0.02	2.997GlyPro: 2.997 ± 0.03	2.146GlyGln: 2.146 ± 0.022	4.418GlyArg: 4.418 ± 0.032	5.086GlySer: 5.086 ± 0.036	3.22GlyThr: 3.22 ± 0.025	3.346GlyVal: 3.346 ± 0.028	0.704GlyTrp: 0.704 ± 0.009	1.667GlyTyr: 1.667 ± 0.02	0.003GlyXaa: 0.003 ± 0.001
His	1.32HisAla: 1.32 ± 0.016	0.659HisCys: 0.659 ± 0.013	1.063HisAsp: 1.063 ± 0.013	1.189HisGlu: 1.189 ± 0.016	1.182HisPhe: 1.182 ± 0.016	1.491HisGly: 1.491 ± 0.023	1.313HisHis: 1.313 ± 0.038	1.233HisIle: 1.233 ± 0.013	1.14HisLys: 1.14 ± 0.018	2.525HisLeu: 2.525 ± 0.023	0.521HisMet: 0.521 ± 0.009	1.006HisAsn: 1.006 ± 0.015	1.639HisPro: 1.639 ± 0.019	1.344HisGln: 1.344 ± 0.022	1.922HisArg: 1.922 ± 0.018	2.094HisSer: 2.094 ± 0.017	1.217HisThr: 1.217 ± 0.015	1.55HisVal: 1.55 ± 0.016	0.358HisTrp: 0.358 ± 0.008	0.786HisTyr: 0.786 ± 0.013	0.002HisXaa: 0.002 ± 0.0
Ile	3.146IleAla: 3.146 ± 0.022	1.046IleCys: 1.046 ± 0.014	2.509IleAsp: 2.509 ± 0.021	2.996IleGlu: 2.996 ± 0.028	2.297IlePhe: 2.297 ± 0.022	2.874IleGly: 2.874 ± 0.024	1.313IleHis: 1.313 ± 0.014	2.636IleIle: 2.636 ± 0.027	4.347IleLys: 4.347 ± 0.066	4.605IleLeu: 4.605 ± 0.035	1.091IleMet: 1.091 ± 0.015	2.458IleAsn: 2.458 ± 0.028	2.823IlePro: 2.823 ± 0.025	1.979IleGln: 1.979 ± 0.022	3.438IleArg: 3.438 ± 0.026	4.376IleSer: 4.376 ± 0.042	2.724IleThr: 2.724 ± 0.025	3.414IleVal: 3.414 ± 0.024	0.583IleTrp: 0.583 ± 0.01	1.421IleTyr: 1.421 ± 0.015	0.004IleXaa: 0.004 ± 0.001
Lys	3.296LysAla: 3.296 ± 0.029	1.141LysCys: 1.141 ± 0.017	2.569LysAsp: 2.569 ± 0.026	3.527LysGlu: 3.527 ± 0.032	2.484LysPhe: 2.484 ± 0.022	2.584LysGly: 2.584 ± 0.024	1.349LysHis: 1.349 ± 0.019	3.778LysIle: 3.778 ± 0.029	4.835LysLys: 4.835 ± 0.052	6.174LysLeu: 6.174 ± 0.05	1.614LysMet: 1.614 ± 0.019	2.855LysAsn: 2.855 ± 0.022	3.08LysPro: 3.08 ± 0.036	1.939LysGln: 1.939 ± 0.021	3.869LysArg: 3.869 ± 0.027	4.99LysSer: 4.99 ± 0.047	3.531LysThr: 3.531 ± 0.027	4.206LysVal: 4.206 ± 0.052	0.737LysTrp: 0.737 ± 0.012	1.652LysTyr: 1.652 ± 0.019	0.007LysXaa: 0.007 ± 0.001
Leu	5.604LeuAla: 5.604 ± 0.033	1.735LeuCys: 1.735 ± 0.02	4.11LeuAsp: 4.11 ± 0.028	5.173LeuGlu: 5.173 ± 0.04	3.242LeuPhe: 3.242 ± 0.03	4.498LeuGly: 4.498 ± 0.029	2.387LeuHis: 2.387 ± 0.024	4.294LeuIle: 4.294 ± 0.042	5.674LeuLys: 5.674 ± 0.04	8.097LeuLeu: 8.097 ± 0.064	1.902LeuMet: 1.902 ± 0.016	4.584LeuAsn: 4.584 ± 0.043	5.317LeuPro: 5.317 ± 0.036	3.932LeuGln: 3.932 ± 0.027	7.087LeuArg: 7.087 ± 0.061	7.23LeuSer: 7.23 ± 0.042	4.908LeuThr: 4.908 ± 0.038	5.027LeuVal: 5.027 ± 0.033	1.032LeuTrp: 1.032 ± 0.012	2.229LeuTyr: 2.229 ± 0.019	0.009LeuXaa: 0.009 ± 0.001
Met	1.616MetAla: 1.616 ± 0.017	0.353MetCys: 0.353 ± 0.007	1.123MetAsp: 1.123 ± 0.014	1.462MetGlu: 1.462 ± 0.016	0.908MetPhe: 0.908 ± 0.01	1.135MetGly: 1.135 ± 0.015	0.4MetHis: 0.4 ± 0.007	1.04MetIle: 1.04 ± 0.013	1.503MetLys: 1.503 ± 0.014	1.714MetLeu: 1.714 ± 0.019	0.683MetMet: 0.683 ± 0.02	1.002MetAsn: 1.002 ± 0.013	1.053MetPro: 1.053 ± 0.014	0.699MetGln: 0.699 ± 0.012	1.511MetArg: 1.511 ± 0.024	1.885MetSer: 1.885 ± 0.02	1.226MetThr: 1.226 ± 0.015	1.299MetVal: 1.299 ± 0.018	0.225MetTrp: 0.225 ± 0.006	0.587MetTyr: 0.587 ± 0.011	0.002MetXaa: 0.002 ± 0.001
Asn	2.474AsnAla: 2.474 ± 0.022	0.94AsnCys: 0.94 ± 0.013	1.98AsnAsp: 1.98 ± 0.019	2.331AsnGlu: 2.331 ± 0.025	4.361AsnPhe: 4.361 ± 0.093	2.731AsnGly: 2.731 ± 0.022	1.087AsnHis: 1.087 ± 0.012	2.275AsnIle: 2.275 ± 0.019	2.209AsnLys: 2.209 ± 0.019	3.857AsnLeu: 3.857 ± 0.028	0.929AsnMet: 0.929 ± 0.013	2.135AsnAsn: 2.135 ± 0.031	2.235AsnPro: 2.235 ± 0.021	1.797AsnGln: 1.797 ± 0.023	2.861AsnArg: 2.861 ± 0.023	4.068AsnSer: 4.068 ± 0.039	2.093AsnThr: 2.093 ± 0.019	2.831AsnVal: 2.831 ± 0.023	0.551AsnTrp: 0.551 ± 0.008	1.333AsnTyr: 1.333 ± 0.017	0.006AsnXaa: 0.006 ± 0.001
Pro	4.168ProAla: 4.168 ± 0.04	1.003ProCys: 1.003 ± 0.02	2.613ProAsp: 2.613 ± 0.022	3.272ProGlu: 3.272 ± 0.028	2.013ProPhe: 2.013 ± 0.018	3.286ProGly: 3.286 ± 0.038	1.416ProHis: 1.416 ± 0.019	2.787ProIle: 2.787 ± 0.025	3.007ProLys: 3.007 ± 0.029	4.61ProLeu: 4.61 ± 0.036	1.055ProMet: 1.055 ± 0.014	2.238ProAsn: 2.238 ± 0.024	5.823ProPro: 5.823 ± 0.097	2.309ProGln: 2.309 ± 0.027	3.641ProArg: 3.641 ± 0.029	5.67ProSer: 5.67 ± 0.047	3.785ProThr: 3.785 ± 0.034	3.588ProVal: 3.588 ± 0.038	0.65ProTrp: 0.65 ± 0.011	1.469ProTyr: 1.469 ± 0.018	0.005ProXaa: 0.005 ± 0.001
Gln	2.358GlnAla: 2.358 ± 0.022	0.787GlnCys: 0.787 ± 0.013	1.703GlnAsp: 1.703 ± 0.018	2.272GlnGlu: 2.272 ± 0.022	1.566GlnPhe: 1.566 ± 0.017	2.051GlnGly: 2.051 ± 0.023	1.159GlnHis: 1.159 ± 0.014	2.162GlnIle: 2.162 ± 0.019	2.298GlnLys: 2.298 ± 0.024	4.596GlnLeu: 4.596 ± 0.058	0.96GlnMet: 0.96 ± 0.013	2.008GlnAsn: 2.008 ± 0.022	2.317GlnPro: 2.317 ± 0.026	2.455GlnGln: 2.455 ± 0.055	2.646GlnArg: 2.646 ± 0.023	3.397GlnSer: 3.397 ± 0.035	2.564GlnThr: 2.564 ± 0.034	2.308GlnVal: 2.308 ± 0.02	0.451GlnTrp: 0.451 ± 0.009	1.099GlnTyr: 1.099 ± 0.015	0.006GlnXaa: 0.006 ± 0.001
Arg	3.966ArgAla: 3.966 ± 0.027	1.408ArgCys: 1.408 ± 0.015	3.425ArgAsp: 3.425 ± 0.047	3.384ArgGlu: 3.384 ± 0.023	2.615ArgPhe: 2.615 ± 0.021	3.628ArgGly: 3.628 ± 0.031	1.927ArgHis: 1.927 ± 0.017	3.652ArgIle: 3.652 ± 0.027	4.24ArgLys: 4.24 ± 0.03	6.066ArgLeu: 6.066 ± 0.036	1.586ArgMet: 1.586 ± 0.021	2.924ArgAsn: 2.924 ± 0.023	4.282ArgPro: 4.282 ± 0.038	2.701ArgGln: 2.701 ± 0.022	7.387ArgArg: 7.387 ± 0.077	6.711ArgSer: 6.711 ± 0.058	4.106ArgThr: 4.106 ± 0.033	3.82ArgVal: 3.82 ± 0.034	0.964ArgTrp: 0.964 ± 0.014	1.803ArgTyr: 1.803 ± 0.018	0.009ArgXaa: 0.009 ± 0.001
Ser	5.806SerAla: 5.806 ± 0.036	1.789SerCys: 1.789 ± 0.021	4.183SerAsp: 4.183 ± 0.032	4.573SerGlu: 4.573 ± 0.034	3.07SerPhe: 3.07 ± 0.024	5.091SerGly: 5.091 ± 0.035	2.04SerHis: 2.04 ± 0.021	4.133SerIle: 4.133 ± 0.031	5.276SerLys: 5.276 ± 0.05	7.143SerLeu: 7.143 ± 0.044	1.731SerMet: 1.731 ± 0.019	3.921SerAsn: 3.921 ± 0.04	5.377SerPro: 5.377 ± 0.051	3.734SerGln: 3.734 ± 0.04	6.626SerArg: 6.626 ± 0.053	10.219SerSer: 10.219 ± 0.082	6.354SerThr: 6.354 ± 0.072	4.78SerVal: 4.78 ± 0.025	1.015SerTrp: 1.015 ± 0.014	2.185SerTyr: 2.185 ± 0.023	0.013SerXaa: 0.013 ± 0.001
Thr	4.08ThrAla: 4.08 ± 0.027	1.158ThrCys: 1.158 ± 0.017	2.567ThrAsp: 2.567 ± 0.023	2.98ThrGlu: 2.98 ± 0.024	2.183ThrPhe: 2.183 ± 0.018	3.222ThrGly: 3.222 ± 0.026	1.257ThrHis: 1.257 ± 0.018	3.042ThrIle: 3.042 ± 0.024	2.948ThrLys: 2.948 ± 0.022	5.036ThrLeu: 5.036 ± 0.035	1.259ThrMet: 1.259 ± 0.014	2.317ThrAsn: 2.317 ± 0.02	3.778ThrPro: 3.778 ± 0.04	2.286ThrGln: 2.286 ± 0.031	3.44ThrArg: 3.44 ± 0.024	6.18ThrSer: 6.18 ± 0.063	4.597ThrThr: 4.597 ± 0.081	3.549ThrVal: 3.549 ± 0.026	0.658ThrTrp: 0.658 ± 0.011	1.523ThrTyr: 1.523 ± 0.016	0.008ThrXaa: 0.008 ± 0.001
Val	3.917ValAla: 3.917 ± 0.031	1.288ValCys: 1.288 ± 0.015	3.172ValAsp: 3.172 ± 0.025	3.59ValGlu: 3.59 ± 0.025	2.323ValPhe: 2.323 ± 0.021	3.22ValGly: 3.22 ± 0.026	1.568ValHis: 1.568 ± 0.018	2.982ValIle: 2.982 ± 0.023	3.627ValLys: 3.627 ± 0.028	5.139ValLeu: 5.139 ± 0.034	1.201ValMet: 1.201 ± 0.015	3.806ValAsn: 3.806 ± 0.056	3.554ValPro: 3.554 ± 0.035	2.689ValGln: 2.689 ± 0.026	3.844ValArg: 3.844 ± 0.023	4.802ValSer: 4.802 ± 0.028	3.343ValThr: 3.343 ± 0.026	3.828ValVal: 3.828 ± 0.029	0.695ValTrp: 0.695 ± 0.011	1.575ValTyr: 1.575 ± 0.016	0.006ValXaa: 0.006 ± 0.001
Trp	0.692TrpAla: 0.692 ± 0.01	0.258TrpCys: 0.258 ± 0.006	0.588TrpAsp: 0.588 ± 0.01	0.615TrpGlu: 0.615 ± 0.011	0.445TrpPhe: 0.445 ± 0.008	0.571TrpGly: 0.571 ± 0.009	0.29TrpHis: 0.29 ± 0.006	0.626TrpIle: 0.626 ± 0.01	0.876TrpLys: 0.876 ± 0.014	0.993TrpLeu: 0.993 ± 0.015	0.269TrpMet: 0.269 ± 0.006	0.621TrpAsn: 0.621 ± 0.01	0.647TrpPro: 0.647 ± 0.01	0.449TrpGln: 0.449 ± 0.008	1.059TrpArg: 1.059 ± 0.013	0.998TrpSer: 0.998 ± 0.013	0.759TrpThr: 0.759 ± 0.009	0.605TrpVal: 0.605 ± 0.011	0.212TrpTrp: 0.212 ± 0.006	0.328TrpTyr: 0.328 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.587TyrAla: 1.587 ± 0.019	0.67TyrCys: 0.67 ± 0.009	1.365TyrAsp: 1.365 ± 0.015	1.48TyrGlu: 1.48 ± 0.016	1.294TyrPhe: 1.294 ± 0.016	1.693TyrGly: 1.693 ± 0.02	0.8TyrHis: 0.8 ± 0.013	1.25TyrIle: 1.25 ± 0.017	1.306TyrLys: 1.306 ± 0.015	2.653TyrLeu: 2.653 ± 0.022	0.55TyrMet: 0.55 ± 0.009	1.193TyrAsn: 1.193 ± 0.016	1.389TyrPro: 1.389 ± 0.017	1.099TyrGln: 1.099 ± 0.016	1.909TyrArg: 1.909 ± 0.017	2.337TyrSer: 2.337 ± 0.022	1.39TyrThr: 1.39 ± 0.019	1.617TyrVal: 1.617 ± 0.017	0.377TyrTrp: 0.377 ± 0.008	0.914TyrTyr: 0.914 ± 0.014	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.001	0.002XaaCys: 0.002 ± 0.0	0.003XaaAsp: 0.003 ± 0.001	0.009XaaGlu: 0.009 ± 0.001	0.005XaaPhe: 0.005 ± 0.001	0.003XaaGly: 0.003 ± 0.001	0.002XaaHis: 0.002 ± 0.001	0.004XaaIle: 0.004 ± 0.001	0.006XaaLys: 0.006 ± 0.001	0.006XaaLeu: 0.006 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.01XaaAsn: 0.01 ± 0.001	0.005XaaPro: 0.005 ± 0.001	0.009XaaGln: 0.009 ± 0.001	0.011XaaArg: 0.011 ± 0.001	0.013XaaSer: 0.013 ± 0.001	0.005XaaThr: 0.005 ± 0.001	0.004XaaVal: 0.004 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.298XaaXaa: 0.298 ± 0.013

Statistics based on 23052 proteins (7171166 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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