Amino acid dipepetide frequency for Pseudorhodobacter antarcticus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.646AlaAla: 18.646 ± 0.206	1.206AlaCys: 1.206 ± 0.034	7.344AlaAsp: 7.344 ± 0.101	6.904AlaGlu: 6.904 ± 0.083	4.609AlaPhe: 4.609 ± 0.062	11.44AlaGly: 11.44 ± 0.129	2.53AlaHis: 2.53 ± 0.06	6.065AlaIle: 6.065 ± 0.082	4.218AlaLys: 4.218 ± 0.081	14.419AlaLeu: 14.419 ± 0.146	4.206AlaMet: 4.206 ± 0.066	3.156AlaAsn: 3.156 ± 0.057	6.036AlaPro: 6.036 ± 0.091	5.343AlaGln: 5.343 ± 0.085	9.052AlaArg: 9.052 ± 0.108	5.587AlaSer: 5.587 ± 0.081	6.78AlaThr: 6.78 ± 0.089	9.253AlaVal: 9.253 ± 0.103	1.498AlaTrp: 1.498 ± 0.036	2.616AlaTyr: 2.616 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	1.212CysAla: 1.212 ± 0.032	0.105CysCys: 0.105 ± 0.009	0.634CysAsp: 0.634 ± 0.027	0.376CysGlu: 0.376 ± 0.021	0.342CysPhe: 0.342 ± 0.016	0.948CysGly: 0.948 ± 0.031	0.268CysHis: 0.268 ± 0.014	0.433CysIle: 0.433 ± 0.02	0.239CysLys: 0.239 ± 0.014	0.875CysLeu: 0.875 ± 0.031	0.211CysMet: 0.211 ± 0.014	0.253CysAsn: 0.253 ± 0.016	0.53CysPro: 0.53 ± 0.021	0.226CysGln: 0.226 ± 0.014	0.531CysArg: 0.531 ± 0.022	0.38CysSer: 0.38 ± 0.018	0.472CysThr: 0.472 ± 0.02	0.68CysVal: 0.68 ± 0.029	0.112CysTrp: 0.112 ± 0.009	0.207CysTyr: 0.207 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.889AspAla: 7.889 ± 0.091	0.524AspCys: 0.524 ± 0.023	3.212AspAsp: 3.212 ± 0.076	2.688AspGlu: 2.688 ± 0.055	2.352AspPhe: 2.352 ± 0.041	5.419AspGly: 5.419 ± 0.089	1.356AspHis: 1.356 ± 0.04	3.033AspIle: 3.033 ± 0.051	1.616AspLys: 1.616 ± 0.042	6.45AspLeu: 6.45 ± 0.08	1.744AspMet: 1.744 ± 0.042	1.23AspAsn: 1.23 ± 0.035	3.381AspPro: 3.381 ± 0.052	2.004AspGln: 2.004 ± 0.042	3.993AspArg: 3.993 ± 0.062	2.163AspSer: 2.163 ± 0.05	3.151AspThr: 3.151 ± 0.082	4.308AspVal: 4.308 ± 0.08	1.131AspTrp: 1.131 ± 0.028	1.475AspTyr: 1.475 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	6.684GluAla: 6.684 ± 0.102	0.327GluCys: 0.327 ± 0.017	2.362GluAsp: 2.362 ± 0.049	2.362GluGlu: 2.362 ± 0.059	1.664GluPhe: 1.664 ± 0.041	3.891GluGly: 3.891 ± 0.071	0.919GluHis: 0.919 ± 0.028	3.006GluIle: 3.006 ± 0.051	1.823GluLys: 1.823 ± 0.044	4.06GluLeu: 4.06 ± 0.067	1.67GluMet: 1.67 ± 0.043	1.556GluAsn: 1.556 ± 0.042	1.973GluPro: 1.973 ± 0.042	1.553GluGln: 1.553 ± 0.036	3.232GluArg: 3.232 ± 0.068	1.844GluSer: 1.844 ± 0.041	3.018GluThr: 3.018 ± 0.051	4.023GluVal: 4.023 ± 0.066	0.72GluTrp: 0.72 ± 0.026	0.975GluTyr: 0.975 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.956PheAla: 4.956 ± 0.067	0.451PheCys: 0.451 ± 0.018	2.93PheAsp: 2.93 ± 0.05	1.932PheGlu: 1.932 ± 0.045	1.423PhePhe: 1.423 ± 0.042	3.987PheGly: 3.987 ± 0.07	0.747PheHis: 0.747 ± 0.03	1.797PheIle: 1.797 ± 0.043	1.053PheLys: 1.053 ± 0.033	3.425PheLeu: 3.425 ± 0.062	0.947PheMet: 0.947 ± 0.03	1.075PheAsn: 1.075 ± 0.037	1.571PhePro: 1.571 ± 0.037	0.977PheGln: 0.977 ± 0.029	1.955PheArg: 1.955 ± 0.041	2.005PheSer: 2.005 ± 0.045	2.227PheThr: 2.227 ± 0.039	2.738PheVal: 2.738 ± 0.048	0.615PheTrp: 0.615 ± 0.027	0.908PheTyr: 0.908 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	10.682GlyAla: 10.682 ± 0.125	0.857GlyCys: 0.857 ± 0.028	4.98GlyAsp: 4.98 ± 0.109	3.792GlyGlu: 3.792 ± 0.06	3.98GlyPhe: 3.98 ± 0.063	7.67GlyGly: 7.67 ± 0.126	1.928GlyHis: 1.928 ± 0.047	4.477GlyIle: 4.477 ± 0.073	3.228GlyLys: 3.228 ± 0.063	9.367GlyLeu: 9.367 ± 0.108	2.802GlyMet: 2.802 ± 0.055	2.331GlyAsn: 2.331 ± 0.09	3.798GlyPro: 3.798 ± 0.057	3.386GlyGln: 3.386 ± 0.067	5.6GlyArg: 5.6 ± 0.078	3.968GlySer: 3.968 ± 0.07	4.781GlyThr: 4.781 ± 0.072	7.011GlyVal: 7.011 ± 0.098	1.499GlyTrp: 1.499 ± 0.038	2.176GlyTyr: 2.176 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.61HisAla: 2.61 ± 0.054	0.249HisCys: 0.249 ± 0.014	1.279HisAsp: 1.279 ± 0.041	0.891HisGlu: 0.891 ± 0.028	0.813HisPhe: 0.813 ± 0.027	1.825HisGly: 1.825 ± 0.052	0.574HisHis: 0.574 ± 0.026	1.111HisIle: 1.111 ± 0.031	0.556HisLys: 0.556 ± 0.023	2.268HisLeu: 2.268 ± 0.05	0.598HisMet: 0.598 ± 0.025	0.503HisAsn: 0.503 ± 0.022	1.381HisPro: 1.381 ± 0.04	0.62HisGln: 0.62 ± 0.022	1.298HisArg: 1.298 ± 0.04	0.963HisSer: 0.963 ± 0.035	0.912HisThr: 0.912 ± 0.028	1.438HisVal: 1.438 ± 0.039	0.351HisTrp: 0.351 ± 0.017	0.54HisTyr: 0.54 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.613IleAla: 7.613 ± 0.093	0.6IleCys: 0.6 ± 0.026	3.407IleAsp: 3.407 ± 0.061	2.9IleGlu: 2.9 ± 0.053	1.845IlePhe: 1.845 ± 0.039	4.907IleGly: 4.907 ± 0.08	0.914IleHis: 0.914 ± 0.033	2.531IleIle: 2.531 ± 0.059	1.651IleLys: 1.651 ± 0.042	4.897IleLeu: 4.897 ± 0.072	1.166IleMet: 1.166 ± 0.035	1.491IleAsn: 1.491 ± 0.042	2.449IlePro: 2.449 ± 0.045	1.128IleGln: 1.128 ± 0.032	2.917IleArg: 2.917 ± 0.053	2.917IleSer: 2.917 ± 0.051	3.517IleThr: 3.517 ± 0.06	3.676IleVal: 3.676 ± 0.064	0.758IleTrp: 0.758 ± 0.031	1.161IleTyr: 1.161 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.889LysAla: 3.889 ± 0.081	0.18LysCys: 0.18 ± 0.014	1.625LysAsp: 1.625 ± 0.049	1.244LysGlu: 1.244 ± 0.042	0.973LysPhe: 0.973 ± 0.032	2.897LysGly: 2.897 ± 0.05	0.643LysHis: 0.643 ± 0.027	1.79LysIle: 1.79 ± 0.04	1.132LysLys: 1.132 ± 0.041	2.94LysLeu: 2.94 ± 0.057	0.999LysMet: 0.999 ± 0.031	0.891LysAsn: 0.891 ± 0.029	1.968LysPro: 1.968 ± 0.049	0.942LysGln: 0.942 ± 0.03	2.286LysArg: 2.286 ± 0.051	1.941LysSer: 1.941 ± 0.048	2.174LysThr: 2.174 ± 0.05	2.246LysVal: 2.246 ± 0.05	0.408LysTrp: 0.408 ± 0.019	0.682LysTyr: 0.682 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	13.738LeuAla: 13.738 ± 0.142	1.045LeuCys: 1.045 ± 0.031	5.756LeuAsp: 5.756 ± 0.087	4.531LeuGlu: 4.531 ± 0.072	3.541LeuPhe: 3.541 ± 0.058	8.708LeuGly: 8.708 ± 0.104	2.039LeuHis: 2.039 ± 0.054	5.421LeuIle: 5.421 ± 0.074	2.91LeuLys: 2.91 ± 0.059	8.935LeuLeu: 8.935 ± 0.129	2.871LeuMet: 2.871 ± 0.051	2.768LeuAsn: 2.768 ± 0.052	5.646LeuPro: 5.646 ± 0.086	2.922LeuGln: 2.922 ± 0.055	7.258LeuArg: 7.258 ± 0.077	6.045LeuSer: 6.045 ± 0.085	6.433LeuThr: 6.433 ± 0.084	6.834LeuVal: 6.834 ± 0.101	1.336LeuTrp: 1.336 ± 0.042	1.933LeuTyr: 1.933 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	3.83MetAla: 3.83 ± 0.064	0.182MetCys: 0.182 ± 0.012	1.566MetAsp: 1.566 ± 0.039	1.297MetGlu: 1.297 ± 0.033	0.892MetPhe: 0.892 ± 0.029	2.713MetGly: 2.713 ± 0.049	0.479MetHis: 0.479 ± 0.02	1.724MetIle: 1.724 ± 0.038	1.128MetLys: 1.128 ± 0.034	2.864MetLeu: 2.864 ± 0.053	0.927MetMet: 0.927 ± 0.031	0.863MetAsn: 0.863 ± 0.029	1.619MetPro: 1.619 ± 0.041	1.103MetGln: 1.103 ± 0.029	1.961MetArg: 1.961 ± 0.044	1.468MetSer: 1.468 ± 0.037	2.305MetThr: 2.305 ± 0.043	2.185MetVal: 2.185 ± 0.044	0.248MetTrp: 0.248 ± 0.016	0.369MetTyr: 0.369 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.365AsnAla: 3.365 ± 0.058	0.265AsnCys: 0.265 ± 0.015	1.685AsnAsp: 1.685 ± 0.083	1.074AsnGlu: 1.074 ± 0.038	1.02AsnPhe: 1.02 ± 0.034	2.633AsnGly: 2.633 ± 0.068	0.555AsnHis: 0.555 ± 0.024	1.472AsnIle: 1.472 ± 0.038	0.714AsnLys: 0.714 ± 0.023	2.691AsnLeu: 2.691 ± 0.055	0.731AsnMet: 0.731 ± 0.026	0.719AsnAsn: 0.719 ± 0.033	1.983AsnPro: 1.983 ± 0.04	0.741AsnGln: 0.741 ± 0.028	1.771AsnArg: 1.771 ± 0.044	1.161AsnSer: 1.161 ± 0.032	1.548AsnThr: 1.548 ± 0.045	1.749AsnVal: 1.749 ± 0.039	0.48AsnTrp: 0.48 ± 0.021	0.64AsnTyr: 0.64 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.181ProAla: 6.181 ± 0.078	0.372ProCys: 0.372 ± 0.018	3.865ProAsp: 3.865 ± 0.06	3.101ProGlu: 3.101 ± 0.048	1.996ProPhe: 1.996 ± 0.047	4.344ProGly: 4.344 ± 0.067	1.184ProHis: 1.184 ± 0.034	2.406ProIle: 2.406 ± 0.045	1.784ProLys: 1.784 ± 0.045	4.845ProLeu: 4.845 ± 0.072	1.525ProMet: 1.525 ± 0.035	1.505ProAsn: 1.505 ± 0.034	2.41ProPro: 2.41 ± 0.055	1.832ProGln: 1.832 ± 0.046	2.787ProArg: 2.787 ± 0.061	2.415ProSer: 2.415 ± 0.048	2.775ProThr: 2.775 ± 0.052	4.033ProVal: 4.033 ± 0.067	0.63ProTrp: 0.63 ± 0.023	1.129ProTyr: 1.129 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.258GlnAla: 4.258 ± 0.066	0.213GlnCys: 0.213 ± 0.013	1.642GlnAsp: 1.642 ± 0.039	1.173GlnGlu: 1.173 ± 0.035	1.136GlnPhe: 1.136 ± 0.032	2.779GlnGly: 2.779 ± 0.051	0.667GlnHis: 0.667 ± 0.027	2.242GlnIle: 2.242 ± 0.052	1.068GlnLys: 1.068 ± 0.027	2.796GlnLeu: 2.796 ± 0.053	1.211GlnMet: 1.211 ± 0.029	1.065GlnAsn: 1.065 ± 0.035	1.661GlnPro: 1.661 ± 0.036	0.973GlnGln: 0.973 ± 0.038	2.2GlnArg: 2.2 ± 0.048	1.942GlnSer: 1.942 ± 0.044	2.467GlnThr: 2.467 ± 0.046	2.407GlnVal: 2.407 ± 0.052	0.414GlnTrp: 0.414 ± 0.017	0.608GlnTyr: 0.608 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	8.678ArgAla: 8.678 ± 0.101	0.481ArgCys: 0.481 ± 0.021	4.054ArgAsp: 4.054 ± 0.058	3.06ArgGlu: 3.06 ± 0.059	2.638ArgPhe: 2.638 ± 0.051	4.724ArgGly: 4.724 ± 0.064	1.484ArgHis: 1.484 ± 0.034	3.581ArgIle: 3.581 ± 0.051	2.186ArgLys: 2.186 ± 0.053	6.946ArgLeu: 6.946 ± 0.086	2.093ArgMet: 2.093 ± 0.041	1.759ArgAsn: 1.759 ± 0.04	3.085ArgPro: 3.085 ± 0.061	2.122ArgGln: 2.122 ± 0.049	4.466ArgArg: 4.466 ± 0.078	2.901ArgSer: 2.901 ± 0.056	2.89ArgThr: 2.89 ± 0.05	4.864ArgVal: 4.864 ± 0.073	0.912ArgTrp: 0.912 ± 0.031	1.477ArgTyr: 1.477 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.726SerAla: 5.726 ± 0.076	0.4SerCys: 0.4 ± 0.018	2.915SerAsp: 2.915 ± 0.053	2.094SerGlu: 2.094 ± 0.052	2.133SerPhe: 2.133 ± 0.045	5.125SerGly: 5.125 ± 0.081	1.082SerHis: 1.082 ± 0.03	2.509SerIle: 2.509 ± 0.047	1.512SerLys: 1.512 ± 0.039	4.932SerLeu: 4.932 ± 0.073	1.296SerMet: 1.296 ± 0.037	1.373SerAsn: 1.373 ± 0.035	2.449SerPro: 2.449 ± 0.044	1.509SerGln: 1.509 ± 0.037	2.872SerArg: 2.872 ± 0.058	2.348SerSer: 2.348 ± 0.058	2.62SerThr: 2.62 ± 0.051	3.823SerVal: 3.823 ± 0.066	0.658SerTrp: 0.658 ± 0.024	1.13SerTyr: 1.13 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	7.18ThrAla: 7.18 ± 0.09	0.534ThrCys: 0.534 ± 0.022	3.445ThrAsp: 3.445 ± 0.051	2.629ThrGlu: 2.629 ± 0.049	2.015ThrPhe: 2.015 ± 0.043	5.41ThrGly: 5.41 ± 0.082	1.286ThrHis: 1.286 ± 0.034	2.965ThrIle: 2.965 ± 0.057	1.788ThrLys: 1.788 ± 0.04	6.49ThrLeu: 6.49 ± 0.094	1.396ThrMet: 1.396 ± 0.038	1.52ThrAsn: 1.52 ± 0.043	3.873ThrPro: 3.873 ± 0.068	1.847ThrGln: 1.847 ± 0.041	3.535ThrArg: 3.535 ± 0.06	2.76ThrSer: 2.76 ± 0.052	3.238ThrThr: 3.238 ± 0.066	4.242ThrVal: 4.242 ± 0.076	0.705ThrTrp: 0.705 ± 0.028	1.298ThrTyr: 1.298 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	9.544ValAla: 9.544 ± 0.111	0.652ValCys: 0.652 ± 0.025	4.126ValAsp: 4.126 ± 0.067	4.081ValGlu: 4.081 ± 0.059	2.861ValPhe: 2.861 ± 0.061	5.696ValGly: 5.696 ± 0.086	1.285ValHis: 1.285 ± 0.038	4.231ValIle: 4.231 ± 0.063	2.215ValLys: 2.215 ± 0.051	7.679ValLeu: 7.679 ± 0.092	2.417ValMet: 2.417 ± 0.048	1.913ValAsn: 1.913 ± 0.045	3.569ValPro: 3.569 ± 0.063	2.441ValGln: 2.441 ± 0.042	4.131ValArg: 4.131 ± 0.067	3.803ValSer: 3.803 ± 0.067	4.897ValThr: 4.897 ± 0.067	5.982ValVal: 5.982 ± 0.087	1.055ValTrp: 1.055 ± 0.037	1.438ValTyr: 1.438 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.605TrpAla: 1.605 ± 0.045	0.134TrpCys: 0.134 ± 0.011	0.774TrpAsp: 0.774 ± 0.026	0.564TrpGlu: 0.564 ± 0.024	0.562TrpPhe: 0.562 ± 0.024	1.114TrpGly: 1.114 ± 0.031	0.358TrpHis: 0.358 ± 0.018	0.638TrpIle: 0.638 ± 0.026	0.408TrpLys: 0.408 ± 0.02	1.601TrpLeu: 1.601 ± 0.04	0.402TrpMet: 0.402 ± 0.02	0.382TrpAsn: 0.382 ± 0.019	0.749TrpPro: 0.749 ± 0.028	0.617TrpGln: 0.617 ± 0.028	1.143TrpArg: 1.143 ± 0.034	0.721TrpSer: 0.721 ± 0.028	0.758TrpThr: 0.758 ± 0.028	1.061TrpVal: 1.061 ± 0.029	0.219TrpTrp: 0.219 ± 0.014	0.272TrpTyr: 0.272 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.622TyrAla: 2.622 ± 0.05	0.255TyrCys: 0.255 ± 0.015	1.518TyrAsp: 1.518 ± 0.039	0.969TyrGlu: 0.969 ± 0.033	0.923TyrPhe: 0.923 ± 0.026	2.081TyrGly: 2.081 ± 0.054	0.483TyrHis: 0.483 ± 0.023	1.012TyrIle: 1.012 ± 0.032	0.62TyrLys: 0.62 ± 0.027	2.187TyrLeu: 2.187 ± 0.044	0.513TyrMet: 0.513 ± 0.024	0.645TyrAsn: 0.645 ± 0.026	0.99TyrPro: 0.99 ± 0.028	0.636TyrGln: 0.636 ± 0.023	1.415TyrArg: 1.415 ± 0.035	1.176TyrSer: 1.176 ± 0.036	1.194TyrThr: 1.194 ± 0.035	1.461TyrVal: 1.461 ± 0.037	0.336TyrTrp: 0.336 ± 0.017	0.55TyrTyr: 0.55 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3792 proteins (1132519 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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