Amino acid dipepetide frequency for Labrenzia suaedae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.215AlaAla: 15.215 ± 0.131
1.064AlaCys: 1.064 ± 0.028
6.403AlaAsp: 6.403 ± 0.073
7.435AlaGlu: 7.435 ± 0.096
4.511AlaPhe: 4.511 ± 0.053
10.309AlaGly: 10.309 ± 0.087
2.023AlaHis: 2.023 ± 0.035
6.034AlaIle: 6.034 ± 0.079
4.267AlaLys: 4.267 ± 0.062
12.465AlaLeu: 12.465 ± 0.126
3.283AlaMet: 3.283 ± 0.045
2.903AlaAsn: 2.903 ± 0.049
4.952AlaPro: 4.952 ± 0.074
3.653AlaGln: 3.653 ± 0.053
7.078AlaArg: 7.078 ± 0.083
6.965AlaSer: 6.965 ± 0.084
5.341AlaThr: 5.341 ± 0.074
8.149AlaVal: 8.149 ± 0.083
1.279AlaTrp: 1.279 ± 0.031
2.535AlaTyr: 2.535 ± 0.038
0.0AlaXaa: 0.0 ± 0.0
Cys
0.939CysAla: 0.939 ± 0.028
0.128CysCys: 0.128 ± 0.01
0.501CysAsp: 0.501 ± 0.018
0.48CysGlu: 0.48 ± 0.02
0.354CysPhe: 0.354 ± 0.016
0.955CysGly: 0.955 ± 0.026
0.248CysHis: 0.248 ± 0.012
0.369CysIle: 0.369 ± 0.017
0.252CysLys: 0.252 ± 0.014
0.991CysLeu: 0.991 ± 0.026
0.189CysMet: 0.189 ± 0.012
0.231CysAsn: 0.231 ± 0.013
0.452CysPro: 0.452 ± 0.018
0.258CysGln: 0.258 ± 0.013
0.524CysArg: 0.524 ± 0.021
0.519CysSer: 0.519 ± 0.023
0.367CysThr: 0.367 ± 0.018
0.596CysVal: 0.596 ± 0.021
0.114CysTrp: 0.114 ± 0.008
0.201CysTyr: 0.201 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
6.193AspAla: 6.193 ± 0.076
0.495AspCys: 0.495 ± 0.018
2.893AspAsp: 2.893 ± 0.059
3.426AspGlu: 3.426 ± 0.052
2.251AspPhe: 2.251 ± 0.039
5.146AspGly: 5.146 ± 0.079
1.212AspHis: 1.212 ± 0.035
3.167AspIle: 3.167 ± 0.052
2.044AspLys: 2.044 ± 0.04
6.659AspLeu: 6.659 ± 0.08
1.53AspMet: 1.53 ± 0.032
1.324AspAsn: 1.324 ± 0.033
3.34AspPro: 3.34 ± 0.065
2.001AspGln: 2.001 ± 0.037
3.754AspArg: 3.754 ± 0.051
2.178AspSer: 2.178 ± 0.041
2.851AspThr: 2.851 ± 0.068
4.029AspVal: 4.029 ± 0.052
0.988AspTrp: 0.988 ± 0.027
1.522AspTyr: 1.522 ± 0.03
0.0AspXaa: 0.0 ± 0.0
Glu
7.861GluAla: 7.861 ± 0.085
0.32GluCys: 0.32 ± 0.015
3.532GluAsp: 3.532 ± 0.057
4.043GluGlu: 4.043 ± 0.063
1.904GluPhe: 1.904 ± 0.038
4.617GluGly: 4.617 ± 0.06
1.145GluHis: 1.145 ± 0.029
3.745GluIle: 3.745 ± 0.051
2.658GluLys: 2.658 ± 0.047
5.677GluLeu: 5.677 ± 0.063
1.583GluMet: 1.583 ± 0.037
1.841GluAsn: 1.841 ± 0.039
2.582GluPro: 2.582 ± 0.051
2.12GluGln: 2.12 ± 0.038
4.215GluArg: 4.215 ± 0.065
2.403GluSer: 2.403 ± 0.043
4.115GluThr: 4.115 ± 0.06
4.017GluVal: 4.017 ± 0.048
0.608GluTrp: 0.608 ± 0.019
0.929GluTyr: 0.929 ± 0.025
0.0GluXaa: 0.0 ± 0.0
Phe
4.375PheAla: 4.375 ± 0.066
0.46PheCys: 0.46 ± 0.019
2.633PheAsp: 2.633 ± 0.042
2.344PheGlu: 2.344 ± 0.041
1.546PhePhe: 1.546 ± 0.038
3.711PheGly: 3.711 ± 0.056
0.745PheHis: 0.745 ± 0.023
1.835PheIle: 1.835 ± 0.04
1.279PheLys: 1.279 ± 0.03
3.865PheLeu: 3.865 ± 0.049
0.896PheMet: 0.896 ± 0.024
1.226PheAsn: 1.226 ± 0.028
1.591PhePro: 1.591 ± 0.034
1.243PheGln: 1.243 ± 0.029
2.175PheArg: 2.175 ± 0.041
2.655PheSer: 2.655 ± 0.045
2.078PheThr: 2.078 ± 0.046
2.702PheVal: 2.702 ± 0.046
0.559PheTrp: 0.559 ± 0.02
0.941PheTyr: 0.941 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
8.619GlyAla: 8.619 ± 0.096
0.855GlyCys: 0.855 ± 0.023
4.35GlyAsp: 4.35 ± 0.105
4.918GlyGlu: 4.918 ± 0.065
3.701GlyPhe: 3.701 ± 0.053
7.462GlyGly: 7.462 ± 0.234
1.861GlyHis: 1.861 ± 0.042
4.776GlyIle: 4.776 ± 0.06
3.86GlyLys: 3.86 ± 0.06
9.336GlyLeu: 9.336 ± 0.095
2.31GlyMet: 2.31 ± 0.044
2.499GlyAsn: 2.499 ± 0.073
3.295GlyPro: 3.295 ± 0.049
2.981GlyGln: 2.981 ± 0.049
5.206GlyArg: 5.206 ± 0.067
5.213GlySer: 5.213 ± 0.084
5.011GlyThr: 5.011 ± 0.115
5.827GlyVal: 5.827 ± 0.067
1.269GlyTrp: 1.269 ± 0.031
2.355GlyTyr: 2.355 ± 0.046
0.0GlyXaa: 0.0 ± 0.0
His
1.9HisAla: 1.9 ± 0.04
0.204HisCys: 0.204 ± 0.011
1.143HisAsp: 1.143 ± 0.035
1.059HisGlu: 1.059 ± 0.03
0.867HisPhe: 0.867 ± 0.024
1.803HisGly: 1.803 ± 0.044
0.529HisHis: 0.529 ± 0.027
0.938HisIle: 0.938 ± 0.027
0.601HisLys: 0.601 ± 0.023
2.091HisLeu: 2.091 ± 0.046
0.513HisMet: 0.513 ± 0.018
0.458HisAsn: 0.458 ± 0.016
1.226HisPro: 1.226 ± 0.03
0.647HisGln: 0.647 ± 0.017
1.147HisArg: 1.147 ± 0.031
1.046HisSer: 1.046 ± 0.028
0.814HisThr: 0.814 ± 0.025
1.388HisVal: 1.388 ± 0.035
0.29HisTrp: 0.29 ± 0.015
0.523HisTyr: 0.523 ± 0.023
0.0HisXaa: 0.0 ± 0.0
Ile
7.029IleAla: 7.029 ± 0.08
0.596IleCys: 0.596 ± 0.02
3.42IleAsp: 3.42 ± 0.053
3.408IleGlu: 3.408 ± 0.052
1.863IlePhe: 1.863 ± 0.045
5.022IleGly: 5.022 ± 0.073
0.919IleHis: 0.919 ± 0.027
2.353IleIle: 2.353 ± 0.043
1.654IleLys: 1.654 ± 0.037
5.204IleLeu: 5.204 ± 0.084
1.059IleMet: 1.059 ± 0.029
1.55IleAsn: 1.55 ± 0.036
2.411IlePro: 2.411 ± 0.043
1.457IleGln: 1.457 ± 0.032
3.387IleArg: 3.387 ± 0.054
3.582IleSer: 3.582 ± 0.055
2.824IleThr: 2.824 ± 0.048
3.848IleVal: 3.848 ± 0.052
0.655IleTrp: 0.655 ± 0.022
1.261IleTyr: 1.261 ± 0.032
0.0IleXaa: 0.0 ± 0.0
Lys
4.965LysAla: 4.965 ± 0.069
0.195LysCys: 0.195 ± 0.012
2.236LysAsp: 2.236 ± 0.046
1.917LysGlu: 1.917 ± 0.038
1.073LysPhe: 1.073 ± 0.027
3.126LysGly: 3.126 ± 0.049
0.606LysHis: 0.606 ± 0.018
2.07LysIle: 2.07 ± 0.038
1.471LysLys: 1.471 ± 0.04
3.701LysLeu: 3.701 ± 0.054
0.899LysMet: 0.899 ± 0.025
1.0LysAsn: 1.0 ± 0.03
2.148LysPro: 2.148 ± 0.046
1.158LysGln: 1.158 ± 0.03
2.377LysArg: 2.377 ± 0.042
2.335LysSer: 2.335 ± 0.044
2.377LysThr: 2.377 ± 0.041
2.899LysVal: 2.899 ± 0.044
0.387LysTrp: 0.387 ± 0.016
0.668LysTyr: 0.668 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
12.768LeuAla: 12.768 ± 0.123
0.959LeuCys: 0.959 ± 0.028
5.935LeuAsp: 5.935 ± 0.078
6.13LeuGlu: 6.13 ± 0.079
3.767LeuPhe: 3.767 ± 0.061
8.269LeuGly: 8.269 ± 0.085
1.71LeuHis: 1.71 ± 0.036
5.44LeuIle: 5.44 ± 0.067
4.443LeuLys: 4.443 ± 0.058
9.668LeuLeu: 9.668 ± 0.123
2.595LeuMet: 2.595 ± 0.045
2.901LeuAsn: 2.901 ± 0.044
5.603LeuPro: 5.603 ± 0.07
3.011LeuGln: 3.011 ± 0.048
6.025LeuArg: 6.025 ± 0.075
7.646LeuSer: 7.646 ± 0.102
6.349LeuThr: 6.349 ± 0.098
7.266LeuVal: 7.266 ± 0.084
1.083LeuTrp: 1.083 ± 0.028
2.043LeuTyr: 2.043 ± 0.038
0.0LeuXaa: 0.0 ± 0.0
Met
2.961MetAla: 2.961 ± 0.042
0.16MetCys: 0.16 ± 0.009
1.281MetAsp: 1.281 ± 0.029
1.315MetGlu: 1.315 ± 0.028
0.751MetPhe: 0.751 ± 0.027
1.9MetGly: 1.9 ± 0.041
0.408MetHis: 0.408 ± 0.015
1.521MetIle: 1.521 ± 0.033
1.145MetLys: 1.145 ± 0.029
2.426MetLeu: 2.426 ± 0.046
0.695MetMet: 0.695 ± 0.023
0.84MetAsn: 0.84 ± 0.026
1.462MetPro: 1.462 ± 0.033
0.81MetGln: 0.81 ± 0.022
1.576MetArg: 1.576 ± 0.037
1.967MetSer: 1.967 ± 0.031
2.087MetThr: 2.087 ± 0.039
1.744MetVal: 1.744 ± 0.034
0.204MetTrp: 0.204 ± 0.012
0.282MetTyr: 0.282 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
3.124AsnAla: 3.124 ± 0.054
0.247AsnCys: 0.247 ± 0.014
1.511AsnAsp: 1.511 ± 0.042
1.414AsnGlu: 1.414 ± 0.032
0.995AsnPhe: 0.995 ± 0.027
2.727AsnGly: 2.727 ± 0.06
0.538AsnHis: 0.538 ± 0.019
1.431AsnIle: 1.431 ± 0.03
0.858AsnLys: 0.858 ± 0.023
2.812AsnLeu: 2.812 ± 0.041
0.71AsnMet: 0.71 ± 0.024
0.712AsnAsn: 0.712 ± 0.027
1.879AsnPro: 1.879 ± 0.04
0.889AsnGln: 0.889 ± 0.025
1.895AsnArg: 1.895 ± 0.043
1.574AsnSer: 1.574 ± 0.039
1.403AsnThr: 1.403 ± 0.036
2.018AsnVal: 2.018 ± 0.041
0.474AsnTrp: 0.474 ± 0.019
0.707AsnTyr: 0.707 ± 0.024
0.0AsnXaa: 0.0 ± 0.0
Pro
5.687ProAla: 5.687 ± 0.073
0.33ProCys: 0.33 ± 0.016
3.608ProAsp: 3.608 ± 0.063
3.978ProGlu: 3.978 ± 0.063
2.042ProPhe: 2.042 ± 0.039
4.279ProGly: 4.279 ± 0.057
0.973ProHis: 0.973 ± 0.026
2.099ProIle: 2.099 ± 0.04
1.782ProLys: 1.782 ± 0.037
4.675ProLeu: 4.675 ± 0.068
1.147ProMet: 1.147 ± 0.027
1.247ProAsn: 1.247 ± 0.03
1.904ProPro: 1.904 ± 0.051
1.634ProGln: 1.634 ± 0.037
2.325ProArg: 2.325 ± 0.043
2.881ProSer: 2.881 ± 0.048
1.969ProThr: 1.969 ± 0.042
4.538ProVal: 4.538 ± 0.075
0.618ProTrp: 0.618 ± 0.022
1.147ProTyr: 1.147 ± 0.026
0.0ProXaa: 0.0 ± 0.0
Gln
4.015GlnAla: 4.015 ± 0.06
0.192GlnCys: 0.192 ± 0.011
1.788GlnAsp: 1.788 ± 0.033
1.85GlnGlu: 1.85 ± 0.041
1.135GlnPhe: 1.135 ± 0.029
2.373GlnGly: 2.373 ± 0.042
0.6GlnHis: 0.6 ± 0.021
2.1GlnIle: 2.1 ± 0.049
1.279GlnLys: 1.279 ± 0.033
2.962GlnLeu: 2.962 ± 0.049
0.972GlnMet: 0.972 ± 0.025
0.989GlnAsn: 0.989 ± 0.031
1.665GlnPro: 1.665 ± 0.045
1.203GlnGln: 1.203 ± 0.032
2.162GlnArg: 2.162 ± 0.042
2.078GlnSer: 2.078 ± 0.045
2.104GlnThr: 2.104 ± 0.039
2.357GlnVal: 2.357 ± 0.041
0.329GlnTrp: 0.329 ± 0.016
0.596GlnTyr: 0.596 ± 0.021
0.0GlnXaa: 0.0 ± 0.0
Arg
5.918ArgAla: 5.918 ± 0.074
0.46ArgCys: 0.46 ± 0.018
3.471ArgAsp: 3.471 ± 0.056
3.804ArgGlu: 3.804 ± 0.061
2.759ArgPhe: 2.759 ± 0.044
4.048ArgGly: 4.048 ± 0.063
1.426ArgHis: 1.426 ± 0.031
3.735ArgIle: 3.735 ± 0.052
2.729ArgLys: 2.729 ± 0.044
7.056ArgLeu: 7.056 ± 0.076
1.771ArgMet: 1.771 ± 0.034
1.847ArgAsn: 1.847 ± 0.034
3.052ArgPro: 3.052 ± 0.055
2.505ArgGln: 2.505 ± 0.044
4.373ArgArg: 4.373 ± 0.069
3.691ArgSer: 3.691 ± 0.062
3.081ArgThr: 3.081 ± 0.041
3.973ArgVal: 3.973 ± 0.056
0.778ArgTrp: 0.778 ± 0.024
1.521ArgTyr: 1.521 ± 0.034
0.0ArgXaa: 0.0 ± 0.0
Ser
6.842SerAla: 6.842 ± 0.088
0.491SerCys: 0.491 ± 0.02
3.376SerAsp: 3.376 ± 0.05
3.391SerGlu: 3.391 ± 0.049
2.698SerPhe: 2.698 ± 0.047
6.451SerGly: 6.451 ± 0.11
1.212SerHis: 1.212 ± 0.029
3.076SerIle: 3.076 ± 0.064
1.981SerLys: 1.981 ± 0.035
6.584SerLeu: 6.584 ± 0.083
1.477SerMet: 1.477 ± 0.034
1.681SerAsn: 1.681 ± 0.033
2.802SerPro: 2.802 ± 0.047
2.025SerGln: 2.025 ± 0.044
3.877SerArg: 3.877 ± 0.056
4.083SerSer: 4.083 ± 0.073
2.888SerThr: 2.888 ± 0.056
4.362SerVal: 4.362 ± 0.057
0.796SerTrp: 0.796 ± 0.023
1.454SerTyr: 1.454 ± 0.032
0.0SerXaa: 0.0 ± 0.0
Thr
6.199ThrAla: 6.199 ± 0.08
0.479ThrCys: 0.479 ± 0.016
3.039ThrAsp: 3.039 ± 0.065
2.771ThrGlu: 2.771 ± 0.048
2.165ThrPhe: 2.165 ± 0.041
5.609ThrGly: 5.609 ± 0.078
0.946ThrHis: 0.946 ± 0.025
2.976ThrIle: 2.976 ± 0.059
1.607ThrLys: 1.607 ± 0.032
5.892ThrLeu: 5.892 ± 0.074
1.198ThrMet: 1.198 ± 0.032
1.44ThrAsn: 1.44 ± 0.042
3.016ThrPro: 3.016 ± 0.048
1.594ThrGln: 1.594 ± 0.053
3.174ThrArg: 3.174 ± 0.045
3.485ThrSer: 3.485 ± 0.064
2.686ThrThr: 2.686 ± 0.056
4.372ThrVal: 4.372 ± 0.081
0.701ThrTrp: 0.701 ± 0.026
1.37ThrTyr: 1.37 ± 0.031
0.0ThrXaa: 0.0 ± 0.0
Val
7.857ValAla: 7.857 ± 0.076
0.633ValCys: 0.633 ± 0.02
3.808ValAsp: 3.808 ± 0.055
4.395ValGlu: 4.395 ± 0.063
2.941ValPhe: 2.941 ± 0.049
4.917ValGly: 4.917 ± 0.073
1.319ValHis: 1.319 ± 0.031
4.181ValIle: 4.181 ± 0.063
2.441ValLys: 2.441 ± 0.037
7.707ValLeu: 7.707 ± 0.089
1.898ValMet: 1.898 ± 0.044
2.103ValAsn: 2.103 ± 0.045
3.746ValPro: 3.746 ± 0.052
2.152ValGln: 2.152 ± 0.038
4.296ValArg: 4.296 ± 0.067
5.034ValSer: 5.034 ± 0.06
4.516ValThr: 4.516 ± 0.08
5.295ValVal: 5.295 ± 0.066
0.89ValTrp: 0.89 ± 0.028
1.558ValTyr: 1.558 ± 0.034
0.0ValXaa: 0.0 ± 0.0
Trp
1.117TrpAla: 1.117 ± 0.027
0.132TrpCys: 0.132 ± 0.009
0.626TrpAsp: 0.626 ± 0.02
0.531TrpGlu: 0.531 ± 0.018
0.524TrpPhe: 0.524 ± 0.019
0.849TrpGly: 0.849 ± 0.024
0.299TrpHis: 0.299 ± 0.015
0.699TrpIle: 0.699 ± 0.021
0.502TrpLys: 0.502 ± 0.022
1.438TrpLeu: 1.438 ± 0.036
0.359TrpMet: 0.359 ± 0.014
0.472TrpAsn: 0.472 ± 0.018
0.658TrpPro: 0.658 ± 0.021
0.605TrpGln: 0.605 ± 0.024
0.916TrpArg: 0.916 ± 0.026
0.852TrpSer: 0.852 ± 0.024
0.751TrpThr: 0.751 ± 0.024
0.759TrpVal: 0.759 ± 0.025
0.201TrpTrp: 0.201 ± 0.014
0.288TrpTyr: 0.288 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.276TyrAla: 2.276 ± 0.037
0.27TyrCys: 0.27 ± 0.014
1.449TyrAsp: 1.449 ± 0.031
1.305TyrGlu: 1.305 ± 0.032
1.012TyrPhe: 1.012 ± 0.029
2.13TyrGly: 2.13 ± 0.044
0.47TyrHis: 0.47 ± 0.02
0.957TyrIle: 0.957 ± 0.028
0.755TyrLys: 0.755 ± 0.023
2.403TyrLeu: 2.403 ± 0.038
0.447TyrMet: 0.447 ± 0.017
0.655TyrAsn: 0.655 ± 0.024
1.079TyrPro: 1.079 ± 0.028
0.803TyrGln: 0.803 ± 0.024
1.514TyrArg: 1.514 ± 0.032
1.361TyrSer: 1.361 ± 0.029
1.11TyrThr: 1.11 ± 0.031
1.551TyrVal: 1.551 ± 0.029
0.355TyrTrp: 0.355 ± 0.015
0.589TyrTyr: 0.589 ± 0.023
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4539 proteins (1505445 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski