Amino acid dipepetide frequency for Red clover powdery mildew-associated totivirus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.323AlaAla: 9.323 ± 0.37
1.243AlaCys: 1.243 ± 0.804
1.865AlaAsp: 1.865 ± 0.406
4.351AlaGlu: 4.351 ± 0.414
3.729AlaPhe: 3.729 ± 1.612
1.865AlaGly: 1.865 ± 0.394
1.243AlaHis: 1.243 ± 0.004
7.458AlaIle: 7.458 ± 0.024
2.486AlaLys: 2.486 ± 0.808
9.944AlaLeu: 9.944 ± 0.768
3.729AlaMet: 3.729 ± 1.612
5.594AlaAsn: 5.594 ± 0.382
2.486AlaPro: 2.486 ± 0.792
3.729AlaGln: 3.729 ± 0.788
8.08AlaArg: 8.08 ± 0.426
4.351AlaSer: 4.351 ± 0.414
8.08AlaThr: 8.08 ± 0.374
6.215AlaVal: 6.215 ± 2.419
0.0AlaTrp: 0.0 ± 0.0
4.972AlaTyr: 4.972 ± 0.016
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.486CysGlu: 2.486 ± 1.608
1.865CysPhe: 1.865 ± 0.406
0.622CysGly: 0.622 ± 0.402
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.865CysLys: 1.865 ± 1.206
1.243CysLeu: 1.243 ± 0.796
0.622CysMet: 0.622 ± 0.402
0.622CysAsn: 0.622 ± 0.398
1.243CysPro: 1.243 ± 0.804
0.0CysGln: 0.0 ± 0.0
0.622CysArg: 0.622 ± 0.398
1.865CysSer: 1.865 ± 1.206
0.0CysThr: 0.0 ± 0.0
0.622CysVal: 0.622 ± 0.402
0.0CysTrp: 0.0 ± 0.0
0.622CysTyr: 0.622 ± 0.398
0.0CysXaa: 0.0 ± 0.0
Asp
4.351AspAla: 4.351 ± 0.386
1.243AspCys: 1.243 ± 0.804
4.351AspAsp: 4.351 ± 1.186
3.729AspGlu: 3.729 ± 1.588
2.486AspPhe: 2.486 ± 1.608
4.351AspGly: 4.351 ± 1.214
2.486AspHis: 2.486 ± 0.792
3.108AspIle: 3.108 ± 0.41
1.243AspLys: 1.243 ± 0.004
6.215AspLeu: 6.215 ± 0.02
1.865AspMet: 1.865 ± 0.406
1.243AspAsn: 1.243 ± 0.796
0.622AspPro: 0.622 ± 0.402
2.486AspGln: 2.486 ± 0.792
1.243AspArg: 1.243 ± 0.004
3.108AspSer: 3.108 ± 1.19
2.486AspThr: 2.486 ± 0.792
5.594AspVal: 5.594 ± 0.418
1.243AspTrp: 1.243 ± 0.804
2.486AspTyr: 2.486 ± 0.008
0.0AspXaa: 0.0 ± 0.0
Glu
5.594GluAla: 5.594 ± 0.382
1.243GluCys: 1.243 ± 0.004
5.594GluAsp: 5.594 ± 1.218
2.486GluGlu: 2.486 ± 0.808
1.865GluPhe: 1.865 ± 0.406
3.729GluGly: 3.729 ± 0.788
3.108GluHis: 3.108 ± 1.21
3.729GluIle: 3.729 ± 0.012
2.486GluLys: 2.486 ± 0.008
4.972GluLeu: 4.972 ± 0.016
0.0GluMet: 0.0 ± 0.0
3.729GluAsn: 3.729 ± 0.012
2.486GluPro: 2.486 ± 0.008
2.486GluGln: 2.486 ± 0.792
4.351GluArg: 4.351 ± 2.014
5.594GluSer: 5.594 ± 2.782
1.243GluThr: 1.243 ± 0.004
1.865GluVal: 1.865 ± 1.206
1.865GluTrp: 1.865 ± 0.406
1.865GluTyr: 1.865 ± 0.394
0.0GluXaa: 0.0 ± 0.0
Phe
1.243PheAla: 1.243 ± 0.004
1.865PheCys: 1.865 ± 0.406
1.865PheAsp: 1.865 ± 0.406
4.351PheGlu: 4.351 ± 1.214
2.486PhePhe: 2.486 ± 0.008
5.594PheGly: 5.594 ± 0.382
0.622PheHis: 0.622 ± 0.398
0.622PheIle: 0.622 ± 0.402
1.865PheLys: 1.865 ± 0.394
3.108PheLeu: 3.108 ± 1.21
1.243PheMet: 1.243 ± 0.65
3.108PheAsn: 3.108 ± 1.19
1.243PhePro: 1.243 ± 0.004
0.622PheGln: 0.622 ± 0.402
0.0PheArg: 0.0 ± 0.0
2.486PheSer: 2.486 ± 0.008
1.243PheThr: 1.243 ± 0.004
3.108PheVal: 3.108 ± 1.21
0.0PheTrp: 0.0 ± 0.0
1.865PheTyr: 1.865 ± 0.394
0.0PheXaa: 0.0 ± 0.0
Gly
4.972GlyAla: 4.972 ± 1.616
1.243GlyCys: 1.243 ± 0.804
4.351GlyAsp: 4.351 ± 0.414
1.865GlyGlu: 1.865 ± 0.406
2.486GlyPhe: 2.486 ± 1.592
3.729GlyGly: 3.729 ± 0.012
1.243GlyHis: 1.243 ± 0.796
2.486GlyIle: 2.486 ± 0.008
4.972GlyLys: 4.972 ± 0.016
4.972GlyLeu: 4.972 ± 1.584
3.729GlyMet: 3.729 ± 0.812
1.243GlyAsn: 1.243 ± 0.004
1.865GlyPro: 1.865 ± 0.406
2.486GlyGln: 2.486 ± 0.008
3.108GlyArg: 3.108 ± 0.39
4.972GlySer: 4.972 ± 0.016
5.594GlyThr: 5.594 ± 1.982
4.351GlyVal: 4.351 ± 1.214
1.865GlyTrp: 1.865 ± 1.206
3.729GlyTyr: 3.729 ± 1.588
0.0GlyXaa: 0.0 ± 0.0
His
1.865HisAla: 1.865 ± 0.394
0.0HisCys: 0.0 ± 0.0
1.243HisAsp: 1.243 ± 0.004
3.108HisGlu: 3.108 ± 0.41
1.243HisPhe: 1.243 ± 0.804
1.865HisGly: 1.865 ± 0.394
0.0HisHis: 0.0 ± 0.0
1.243HisIle: 1.243 ± 0.004
0.622HisLys: 0.622 ± 0.398
2.486HisLeu: 2.486 ± 0.808
0.622HisMet: 0.622 ± 0.402
1.243HisAsn: 1.243 ± 0.004
0.622HisPro: 0.622 ± 0.402
0.0HisGln: 0.0 ± 0.0
1.243HisArg: 1.243 ± 0.004
1.865HisSer: 1.865 ± 0.406
2.486HisThr: 2.486 ± 0.808
3.729HisVal: 3.729 ± 0.812
0.622HisTrp: 0.622 ± 0.398
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.351IleAla: 4.351 ± 0.386
0.0IleCys: 0.0 ± 0.0
4.351IleAsp: 4.351 ± 1.186
4.351IleGlu: 4.351 ± 0.386
0.622IlePhe: 0.622 ± 0.398
1.243IleGly: 1.243 ± 0.004
1.243IleHis: 1.243 ± 0.804
0.622IleIle: 0.622 ± 0.402
1.865IleLys: 1.865 ± 0.406
2.486IleLeu: 2.486 ± 0.808
0.622IleMet: 0.622 ± 0.398
0.0IleAsn: 0.0 ± 0.0
1.865IlePro: 1.865 ± 0.406
0.622IleGln: 0.622 ± 0.402
7.458IleArg: 7.458 ± 0.024
6.215IleSer: 6.215 ± 0.78
1.865IleThr: 1.865 ± 1.194
3.729IleVal: 3.729 ± 1.588
0.0IleTrp: 0.0 ± 0.0
1.865IleTyr: 1.865 ± 0.406
0.0IleXaa: 0.0 ± 0.0
Lys
6.837LysAla: 6.837 ± 2.821
0.622LysCys: 0.622 ± 0.402
2.486LysAsp: 2.486 ± 0.808
3.108LysGlu: 3.108 ± 1.21
3.108LysPhe: 3.108 ± 0.39
0.622LysGly: 0.622 ± 0.398
0.622LysHis: 0.622 ± 0.402
2.486LysIle: 2.486 ± 0.808
3.108LysLys: 3.108 ± 1.19
6.215LysLeu: 6.215 ± 0.02
1.243LysMet: 1.243 ± 0.004
0.622LysAsn: 0.622 ± 0.402
0.622LysPro: 0.622 ± 0.398
2.486LysGln: 2.486 ± 0.008
1.865LysArg: 1.865 ± 1.194
0.622LysSer: 0.622 ± 0.402
2.486LysThr: 2.486 ± 0.808
0.622LysVal: 0.622 ± 0.398
1.865LysTrp: 1.865 ± 0.394
2.486LysTyr: 2.486 ± 0.008
0.0LysXaa: 0.0 ± 0.0
Leu
14.295LeuAla: 14.295 ± 1.246
1.243LeuCys: 1.243 ± 0.804
1.865LeuAsp: 1.865 ± 0.394
6.837LeuGlu: 6.837 ± 0.422
3.108LeuPhe: 3.108 ± 0.39
9.944LeuGly: 9.944 ± 0.032
2.486LeuHis: 2.486 ± 0.008
5.594LeuIle: 5.594 ± 2.782
1.865LeuLys: 1.865 ± 0.406
6.837LeuLeu: 6.837 ± 0.378
2.486LeuMet: 2.486 ± 0.792
6.215LeuAsn: 6.215 ± 1.58
6.215LeuPro: 6.215 ± 0.78
4.351LeuGln: 4.351 ± 1.214
6.215LeuArg: 6.215 ± 0.02
8.08LeuSer: 8.08 ± 2.026
5.594LeuThr: 5.594 ± 0.382
6.215LeuVal: 6.215 ± 1.58
1.865LeuTrp: 1.865 ± 0.406
0.622LeuTyr: 0.622 ± 0.398
0.0LeuXaa: 0.0 ± 0.0
Met
2.486MetAla: 2.486 ± 0.792
0.0MetCys: 0.0 ± 0.0
1.865MetAsp: 1.865 ± 0.406
0.622MetGlu: 0.622 ± 0.402
0.0MetPhe: 0.0 ± 0.0
1.243MetGly: 1.243 ± 0.804
0.622MetHis: 0.622 ± 0.402
1.243MetIle: 1.243 ± 0.004
1.865MetLys: 1.865 ± 0.406
1.243MetLeu: 1.243 ± 0.004
0.622MetMet: 0.622 ± 0.402
1.865MetAsn: 1.865 ± 0.406
0.622MetPro: 0.622 ± 0.402
0.0MetGln: 0.0 ± 0.0
1.243MetArg: 1.243 ± 0.804
3.729MetSer: 3.729 ± 0.812
0.0MetThr: 0.0 ± 0.0
1.865MetVal: 1.865 ± 1.194
1.243MetTrp: 1.243 ± 0.004
0.622MetTyr: 0.622 ± 0.402
0.0MetXaa: 0.0 ± 0.0
Asn
3.108AsnAla: 3.108 ± 0.41
0.0AsnCys: 0.0 ± 0.0
1.243AsnAsp: 1.243 ± 0.796
2.486AsnGlu: 2.486 ± 1.592
0.622AsnPhe: 0.622 ± 0.402
3.108AsnGly: 3.108 ± 1.19
1.865AsnHis: 1.865 ± 1.194
1.243AsnIle: 1.243 ± 0.004
1.243AsnLys: 1.243 ± 0.804
4.351AsnLeu: 4.351 ± 0.414
1.243AsnMet: 1.243 ± 0.308
1.243AsnAsn: 1.243 ± 0.004
1.243AsnPro: 1.243 ± 0.796
0.0AsnGln: 0.0 ± 0.0
4.351AsnArg: 4.351 ± 1.986
2.486AsnSer: 2.486 ± 0.792
4.351AsnThr: 4.351 ± 1.186
3.729AsnVal: 3.729 ± 1.612
0.622AsnTrp: 0.622 ± 0.398
1.243AsnTyr: 1.243 ± 0.804
0.0AsnXaa: 0.0 ± 0.0
Pro
2.486ProAla: 2.486 ± 0.008
0.0ProCys: 0.0 ± 0.0
3.108ProAsp: 3.108 ± 0.41
1.865ProGlu: 1.865 ± 0.406
0.622ProPhe: 0.622 ± 0.402
3.108ProGly: 3.108 ± 0.41
0.622ProHis: 0.622 ± 0.402
1.243ProIle: 1.243 ± 0.004
1.243ProLys: 1.243 ± 0.796
5.594ProLeu: 5.594 ± 0.382
0.622ProMet: 0.622 ± 0.402
0.0ProAsn: 0.0 ± 0.0
2.486ProPro: 2.486 ± 0.792
0.0ProGln: 0.0 ± 0.0
1.243ProArg: 1.243 ± 0.004
2.486ProSer: 2.486 ± 0.792
4.972ProThr: 4.972 ± 1.584
1.243ProVal: 1.243 ± 0.004
0.0ProTrp: 0.0 ± 0.0
1.865ProTyr: 1.865 ± 0.394
0.0ProXaa: 0.0 ± 0.0
Gln
2.486GlnAla: 2.486 ± 0.808
0.622GlnCys: 0.622 ± 0.398
2.486GlnAsp: 2.486 ± 0.792
0.622GlnGlu: 0.622 ± 0.402
1.865GlnPhe: 1.865 ± 1.206
1.243GlnGly: 1.243 ± 0.004
1.865GlnHis: 1.865 ± 0.406
0.622GlnIle: 0.622 ± 0.398
1.243GlnLys: 1.243 ± 0.804
4.351GlnLeu: 4.351 ± 0.414
0.0GlnMet: 0.0 ± 0.0
1.243GlnAsn: 1.243 ± 0.004
1.865GlnPro: 1.865 ± 0.394
1.865GlnGln: 1.865 ± 0.406
3.108GlnArg: 3.108 ± 0.41
1.865GlnSer: 1.865 ± 0.394
1.243GlnThr: 1.243 ± 0.004
1.865GlnVal: 1.865 ± 1.206
0.622GlnTrp: 0.622 ± 0.398
1.243GlnTyr: 1.243 ± 0.004
0.0GlnXaa: 0.0 ± 0.0
Arg
9.323ArgAla: 9.323 ± 0.43
1.243ArgCys: 1.243 ± 0.004
3.108ArgAsp: 3.108 ± 0.41
3.108ArgGlu: 3.108 ± 1.19
1.243ArgPhe: 1.243 ± 0.004
4.351ArgGly: 4.351 ± 0.414
2.486ArgHis: 2.486 ± 0.808
1.865ArgIle: 1.865 ± 0.406
1.243ArgLys: 1.243 ± 0.796
8.701ArgLeu: 8.701 ± 3.172
0.0ArgMet: 0.0 ± 0.0
2.486ArgAsn: 2.486 ± 0.792
1.243ArgPro: 1.243 ± 0.804
1.865ArgGln: 1.865 ± 0.406
3.729ArgArg: 3.729 ± 1.612
5.594ArgSer: 5.594 ± 1.182
3.729ArgThr: 3.729 ± 0.012
5.594ArgVal: 5.594 ± 2.018
1.243ArgTrp: 1.243 ± 0.004
1.243ArgTyr: 1.243 ± 0.004
0.0ArgXaa: 0.0 ± 0.0
Ser
4.351SerAla: 4.351 ± 0.386
0.0SerCys: 0.0 ± 0.0
0.622SerAsp: 0.622 ± 0.398
6.215SerGlu: 6.215 ± 1.58
3.108SerPhe: 3.108 ± 0.39
6.215SerGly: 6.215 ± 1.58
3.108SerHis: 3.108 ± 0.41
4.351SerIle: 4.351 ± 0.414
4.972SerLys: 4.972 ± 0.816
5.594SerLeu: 5.594 ± 0.382
1.243SerMet: 1.243 ± 0.004
1.865SerAsn: 1.865 ± 0.394
1.243SerPro: 1.243 ± 0.004
4.972SerGln: 4.972 ± 2.416
3.729SerArg: 3.729 ± 0.812
8.08SerSer: 8.08 ± 0.374
6.837SerThr: 6.837 ± 2.778
7.458SerVal: 7.458 ± 3.176
0.622SerTrp: 0.622 ± 0.398
3.108SerTyr: 3.108 ± 0.41
0.0SerXaa: 0.0 ± 0.0
Thr
3.729ThrAla: 3.729 ± 1.588
1.243ThrCys: 1.243 ± 0.004
2.486ThrAsp: 2.486 ± 0.008
2.486ThrGlu: 2.486 ± 0.792
4.351ThrPhe: 4.351 ± 0.414
2.486ThrGly: 2.486 ± 1.608
1.243ThrHis: 1.243 ± 0.804
3.108ThrIle: 3.108 ± 0.39
4.351ThrLys: 4.351 ± 1.214
9.944ThrLeu: 9.944 ± 3.168
1.243ThrMet: 1.243 ± 0.796
1.865ThrAsn: 1.865 ± 0.406
1.243ThrPro: 1.243 ± 0.796
1.243ThrGln: 1.243 ± 0.804
4.972ThrArg: 4.972 ± 1.584
7.458ThrSer: 7.458 ± 3.176
6.837ThrThr: 6.837 ± 1.178
1.243ThrVal: 1.243 ± 0.004
0.622ThrTrp: 0.622 ± 0.398
3.729ThrTyr: 3.729 ± 0.788
0.0ThrXaa: 0.0 ± 0.0
Val
5.594ValAla: 5.594 ± 1.218
1.865ValCys: 1.865 ± 0.406
8.08ValAsp: 8.08 ± 0.374
4.351ValGlu: 4.351 ± 2.014
2.486ValPhe: 2.486 ± 0.792
3.108ValGly: 3.108 ± 0.39
0.622ValHis: 0.622 ± 0.402
2.486ValIle: 2.486 ± 1.592
3.729ValLys: 3.729 ± 0.812
6.837ValLeu: 6.837 ± 4.421
0.622ValMet: 0.622 ± 0.402
3.729ValAsn: 3.729 ± 0.788
3.729ValPro: 3.729 ± 0.012
2.486ValGln: 2.486 ± 0.008
3.729ValArg: 3.729 ± 0.012
3.729ValSer: 3.729 ± 0.012
3.108ValThr: 3.108 ± 0.41
3.729ValVal: 3.729 ± 0.012
0.622ValTrp: 0.622 ± 0.398
1.243ValTyr: 1.243 ± 0.004
0.0ValXaa: 0.0 ± 0.0
Trp
1.865TrpAla: 1.865 ± 0.406
0.0TrpCys: 0.0 ± 0.0
0.622TrpAsp: 0.622 ± 0.402
0.0TrpGlu: 0.0 ± 0.0
0.622TrpPhe: 0.622 ± 0.402
1.865TrpGly: 1.865 ± 0.406
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.622TrpLys: 0.622 ± 0.402
2.486TrpLeu: 2.486 ± 0.792
0.622TrpMet: 0.622 ± 0.402
0.0TrpAsn: 0.0 ± 0.0
0.622TrpPro: 0.622 ± 0.398
0.622TrpGln: 0.622 ± 0.398
1.865TrpArg: 1.865 ± 0.394
0.622TrpSer: 0.622 ± 0.398
1.243TrpThr: 1.243 ± 0.004
1.243TrpVal: 1.243 ± 0.804
1.243TrpTrp: 1.243 ± 0.004
1.243TrpTyr: 1.243 ± 0.796
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.486TyrAla: 2.486 ± 0.808
0.622TyrCys: 0.622 ± 0.402
4.351TyrAsp: 4.351 ± 1.186
1.865TyrGlu: 1.865 ± 0.394
0.622TyrPhe: 0.622 ± 0.398
4.972TyrGly: 4.972 ± 0.784
0.622TyrHis: 0.622 ± 0.402
1.865TyrIle: 1.865 ± 0.394
1.243TyrLys: 1.243 ± 0.796
4.351TyrLeu: 4.351 ± 0.414
0.0TyrMet: 0.0 ± 0.0
2.486TyrAsn: 2.486 ± 0.792
1.243TyrPro: 1.243 ± 0.796
0.0TyrGln: 0.0 ± 0.0
1.243TyrArg: 1.243 ± 0.004
2.486TyrSer: 2.486 ± 0.008
2.486TyrThr: 2.486 ± 0.008
1.865TyrVal: 1.865 ± 0.406
1.243TyrTrp: 1.243 ± 0.004
1.243TyrTyr: 1.243 ± 0.004
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1610 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski