Amino acid dipepetide frequency for Magnetofaba australis IT-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.655AlaAla: 14.655 ± 0.166	1.102AlaCys: 1.102 ± 0.03	6.412AlaAsp: 6.412 ± 0.085	7.591AlaGlu: 7.591 ± 0.114	3.914AlaPhe: 3.914 ± 0.053	8.062AlaGly: 8.062 ± 0.104	2.889AlaHis: 2.889 ± 0.049	5.623AlaIle: 5.623 ± 0.068	4.096AlaLys: 4.096 ± 0.073	14.468AlaLeu: 14.468 ± 0.151	3.524AlaMet: 3.524 ± 0.066	3.277AlaAsn: 3.277 ± 0.06	6.063AlaPro: 6.063 ± 0.099	6.789AlaGln: 6.789 ± 0.1	8.14AlaArg: 8.14 ± 0.089	5.548AlaSer: 5.548 ± 0.086	4.853AlaThr: 4.853 ± 0.068	7.339AlaVal: 7.339 ± 0.101	1.69AlaTrp: 1.69 ± 0.04	2.371AlaTyr: 2.371 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	1.123CysAla: 1.123 ± 0.029	0.125CysCys: 0.125 ± 0.01	0.61CysAsp: 0.61 ± 0.024	0.58CysGlu: 0.58 ± 0.021	0.31CysPhe: 0.31 ± 0.015	0.937CysGly: 0.937 ± 0.032	0.33CysHis: 0.33 ± 0.022	0.344CysIle: 0.344 ± 0.019	0.245CysLys: 0.245 ± 0.013	0.869CysLeu: 0.869 ± 0.029	0.201CysMet: 0.201 ± 0.015	0.279CysAsn: 0.279 ± 0.015	0.532CysPro: 0.532 ± 0.022	0.343CysGln: 0.343 ± 0.016	0.694CysArg: 0.694 ± 0.025	0.422CysSer: 0.422 ± 0.02	0.293CysThr: 0.293 ± 0.013	0.702CysVal: 0.702 ± 0.023	0.112CysTrp: 0.112 ± 0.01	0.243CysTyr: 0.243 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	7.852AspAla: 7.852 ± 0.085	0.501AspCys: 0.501 ± 0.019	3.455AspAsp: 3.455 ± 0.063	3.712AspGlu: 3.712 ± 0.068	1.979AspPhe: 1.979 ± 0.043	4.96AspGly: 4.96 ± 0.112	1.418AspHis: 1.418 ± 0.035	2.543AspIle: 2.543 ± 0.045	1.952AspLys: 1.952 ± 0.042	6.093AspLeu: 6.093 ± 0.07	1.223AspMet: 1.223 ± 0.034	1.596AspAsn: 1.596 ± 0.036	3.373AspPro: 3.373 ± 0.062	2.08AspGln: 2.08 ± 0.039	3.15AspArg: 3.15 ± 0.052	2.574AspSer: 2.574 ± 0.048	1.903AspThr: 1.903 ± 0.045	3.625AspVal: 3.625 ± 0.064	0.843AspTrp: 0.843 ± 0.023	1.55AspTyr: 1.55 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	8.048GluAla: 8.048 ± 0.133	0.44GluCys: 0.44 ± 0.019	2.551GluAsp: 2.551 ± 0.054	4.474GluGlu: 4.474 ± 0.117	1.775GluPhe: 1.775 ± 0.044	4.038GluGly: 4.038 ± 0.065	1.376GluHis: 1.376 ± 0.033	3.532GluIle: 3.532 ± 0.056	2.65GluLys: 2.65 ± 0.058	6.316GluLeu: 6.316 ± 0.078	2.017GluMet: 2.017 ± 0.044	1.891GluAsn: 1.891 ± 0.041	2.976GluPro: 2.976 ± 0.087	3.56GluGln: 3.56 ± 0.066	5.234GluArg: 5.234 ± 0.075	3.9GluSer: 3.9 ± 0.074	3.215GluThr: 3.215 ± 0.053	3.67GluVal: 3.67 ± 0.061	0.773GluTrp: 0.773 ± 0.027	1.185GluTyr: 1.185 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.471PheAla: 3.471 ± 0.055	0.408PheCys: 0.408 ± 0.017	2.502PheAsp: 2.502 ± 0.046	2.083PheGlu: 2.083 ± 0.043	1.358PhePhe: 1.358 ± 0.039	2.851PheGly: 2.851 ± 0.053	0.992PheHis: 0.992 ± 0.027	1.59PheIle: 1.59 ± 0.04	1.163PheLys: 1.163 ± 0.033	3.552PheLeu: 3.552 ± 0.061	0.75PheMet: 0.75 ± 0.025	1.176PheAsn: 1.176 ± 0.031	1.51PhePro: 1.51 ± 0.033	1.266PheGln: 1.266 ± 0.032	1.948PheArg: 1.948 ± 0.036	2.321PheSer: 2.321 ± 0.045	2.002PheThr: 2.002 ± 0.046	2.249PheVal: 2.249 ± 0.041	0.479PheTrp: 0.479 ± 0.018	0.881PheTyr: 0.881 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	9.016GlyAla: 9.016 ± 0.114	0.895GlyCys: 0.895 ± 0.03	4.617GlyAsp: 4.617 ± 0.1	5.098GlyGlu: 5.098 ± 0.071	3.042GlyPhe: 3.042 ± 0.043	6.712GlyGly: 6.712 ± 0.107	1.871GlyHis: 1.871 ± 0.044	3.406GlyIle: 3.406 ± 0.056	3.198GlyLys: 3.198 ± 0.058	8.015GlyLeu: 8.015 ± 0.084	2.315GlyMet: 2.315 ± 0.046	1.988GlyAsn: 1.988 ± 0.05	2.647GlyPro: 2.647 ± 0.045	3.156GlyGln: 3.156 ± 0.064	5.083GlyArg: 5.083 ± 0.076	3.813GlySer: 3.813 ± 0.067	2.365GlyThr: 2.365 ± 0.069	7.067GlyVal: 7.067 ± 0.094	1.298GlyTrp: 1.298 ± 0.034	2.262GlyTyr: 2.262 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.76HisAla: 2.76 ± 0.048	0.294HisCys: 0.294 ± 0.015	1.318HisAsp: 1.318 ± 0.032	1.325HisGlu: 1.325 ± 0.034	0.961HisPhe: 0.961 ± 0.027	2.131HisGly: 2.131 ± 0.044	0.843HisHis: 0.843 ± 0.029	1.13HisIle: 1.13 ± 0.032	0.827HisLys: 0.827 ± 0.022	2.638HisLeu: 2.638 ± 0.048	0.587HisMet: 0.587 ± 0.021	0.72HisAsn: 0.72 ± 0.024	1.564HisPro: 1.564 ± 0.04	1.013HisGln: 1.013 ± 0.028	1.489HisArg: 1.489 ± 0.037	1.129HisSer: 1.129 ± 0.026	1.1HisThr: 1.1 ± 0.029	1.557HisVal: 1.557 ± 0.035	0.418HisTrp: 0.418 ± 0.021	0.643HisTyr: 0.643 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.62IleAla: 5.62 ± 0.07	0.489IleCys: 0.489 ± 0.02	3.126IleAsp: 3.126 ± 0.052	3.163IleGlu: 3.163 ± 0.051	1.476IlePhe: 1.476 ± 0.038	3.924IleGly: 3.924 ± 0.056	1.38IleHis: 1.38 ± 0.029	2.298IleIle: 2.298 ± 0.044	1.729IleLys: 1.729 ± 0.037	4.814IleLeu: 4.814 ± 0.063	0.947IleMet: 0.947 ± 0.025	1.79IleAsn: 1.79 ± 0.042	2.569IlePro: 2.569 ± 0.044	1.955IleGln: 1.955 ± 0.038	3.006IleArg: 3.006 ± 0.046	2.927IleSer: 2.927 ± 0.049	2.902IleThr: 2.902 ± 0.052	3.073IleVal: 3.073 ± 0.049	0.519IleTrp: 0.519 ± 0.02	1.078IleTyr: 1.078 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.694LysAla: 3.694 ± 0.063	0.224LysCys: 0.224 ± 0.016	1.417LysAsp: 1.417 ± 0.039	2.157LysGlu: 2.157 ± 0.052	0.944LysPhe: 0.944 ± 0.029	2.552LysGly: 2.552 ± 0.055	0.781LysHis: 0.781 ± 0.026	1.774LysIle: 1.774 ± 0.035	1.601LysLys: 1.601 ± 0.044	3.678LysLeu: 3.678 ± 0.067	0.959LysMet: 0.959 ± 0.028	1.058LysAsn: 1.058 ± 0.029	2.266LysPro: 2.266 ± 0.046	1.967LysGln: 1.967 ± 0.04	3.249LysArg: 3.249 ± 0.059	2.293LysSer: 2.293 ± 0.049	1.759LysThr: 1.759 ± 0.041	1.968LysVal: 1.968 ± 0.045	0.429LysTrp: 0.429 ± 0.019	0.683LysTyr: 0.683 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	12.86LeuAla: 12.86 ± 0.139	1.048LeuCys: 1.048 ± 0.028	6.22LeuAsp: 6.22 ± 0.066	6.757LeuGlu: 6.757 ± 0.089	4.144LeuPhe: 4.144 ± 0.07	7.896LeuGly: 7.896 ± 0.086	2.427LeuHis: 2.427 ± 0.048	5.023LeuIle: 5.023 ± 0.067	4.052LeuLys: 4.052 ± 0.067	11.588LeuLeu: 11.588 ± 0.159	2.794LeuMet: 2.794 ± 0.051	3.396LeuAsn: 3.396 ± 0.045	5.299LeuPro: 5.299 ± 0.065	4.009LeuGln: 4.009 ± 0.062	7.409LeuArg: 7.409 ± 0.101	6.685LeuSer: 6.685 ± 0.079	6.295LeuThr: 6.295 ± 0.087	5.869LeuVal: 5.869 ± 0.072	1.305LeuTrp: 1.305 ± 0.041	2.352LeuTyr: 2.352 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	3.65MetAla: 3.65 ± 0.056	0.181MetCys: 0.181 ± 0.013	1.606MetAsp: 1.606 ± 0.032	1.615MetGlu: 1.615 ± 0.039	0.695MetPhe: 0.695 ± 0.025	2.397MetGly: 2.397 ± 0.051	0.46MetHis: 0.46 ± 0.019	1.206MetIle: 1.206 ± 0.031	0.868MetLys: 0.868 ± 0.025	2.681MetLeu: 2.681 ± 0.051	0.733MetMet: 0.733 ± 0.027	0.847MetAsn: 0.847 ± 0.024	1.295MetPro: 1.295 ± 0.031	1.157MetGln: 1.157 ± 0.028	2.004MetArg: 2.004 ± 0.041	1.704MetSer: 1.704 ± 0.037	1.547MetThr: 1.547 ± 0.037	1.669MetVal: 1.669 ± 0.038	0.247MetTrp: 0.247 ± 0.013	0.302MetTyr: 0.302 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.669AsnAla: 3.669 ± 0.051	0.254AsnCys: 0.254 ± 0.017	1.628AsnAsp: 1.628 ± 0.038	1.514AsnGlu: 1.514 ± 0.035	0.944AsnPhe: 0.944 ± 0.028	2.567AsnGly: 2.567 ± 0.053	0.77AsnHis: 0.77 ± 0.024	1.41AsnIle: 1.41 ± 0.035	0.961AsnLys: 0.961 ± 0.027	3.225AsnLeu: 3.225 ± 0.05	0.752AsnMet: 0.752 ± 0.025	0.832AsnAsn: 0.832 ± 0.031	2.08AsnPro: 2.08 ± 0.045	1.278AsnGln: 1.278 ± 0.028	2.067AsnArg: 2.067 ± 0.041	1.327AsnSer: 1.327 ± 0.039	1.311AsnThr: 1.311 ± 0.032	1.813AsnVal: 1.813 ± 0.042	0.429AsnTrp: 0.429 ± 0.019	0.641AsnTyr: 0.641 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	5.083ProAla: 5.083 ± 0.079	0.382ProCys: 0.382 ± 0.018	3.28ProAsp: 3.28 ± 0.053	3.827ProGlu: 3.827 ± 0.069	1.873ProPhe: 1.873 ± 0.035	3.736ProGly: 3.736 ± 0.062	1.275ProHis: 1.275 ± 0.034	2.388ProIle: 2.388 ± 0.047	1.726ProLys: 1.726 ± 0.039	5.172ProLeu: 5.172 ± 0.073	1.378ProMet: 1.378 ± 0.034	1.491ProAsn: 1.491 ± 0.037	2.896ProPro: 2.896 ± 0.067	2.51ProGln: 2.51 ± 0.053	2.598ProArg: 2.598 ± 0.057	2.383ProSer: 2.383 ± 0.046	2.442ProThr: 2.442 ± 0.05	3.486ProVal: 3.486 ± 0.053	0.762ProTrp: 0.762 ± 0.025	1.214ProTyr: 1.214 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	5.823GlnAla: 5.823 ± 0.101	0.376GlnCys: 0.376 ± 0.018	1.642GlnAsp: 1.642 ± 0.038	2.859GlnGlu: 2.859 ± 0.059	1.292GlnPhe: 1.292 ± 0.031	3.175GlnGly: 3.175 ± 0.055	0.986GlnHis: 0.986 ± 0.027	2.219GlnIle: 2.219 ± 0.046	1.395GlnLys: 1.395 ± 0.037	4.251GlnLeu: 4.251 ± 0.06	1.398GlnMet: 1.398 ± 0.033	1.149GlnAsn: 1.149 ± 0.033	2.286GlnPro: 2.286 ± 0.049	2.673GlnGln: 2.673 ± 0.065	3.785GlnArg: 3.785 ± 0.07	2.694GlnSer: 2.694 ± 0.058	2.47GlnThr: 2.47 ± 0.049	2.713GlnVal: 2.713 ± 0.051	0.832GlnTrp: 0.832 ± 0.027	0.801GlnTyr: 0.801 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	7.679ArgAla: 7.679 ± 0.097	0.648ArgCys: 0.648 ± 0.024	3.949ArgAsp: 3.949 ± 0.06	4.436ArgGlu: 4.436 ± 0.075	3.029ArgPhe: 3.029 ± 0.055	4.211ArgGly: 4.211 ± 0.06	1.94ArgHis: 1.94 ± 0.043	4.243ArgIle: 4.243 ± 0.057	2.466ArgLys: 2.466 ± 0.051	7.89ArgLeu: 7.89 ± 0.095	2.057ArgMet: 2.057 ± 0.043	2.126ArgAsn: 2.126 ± 0.036	2.694ArgPro: 2.694 ± 0.045	3.285ArgGln: 3.285 ± 0.055	5.137ArgArg: 5.137 ± 0.086	3.15ArgSer: 3.15 ± 0.053	2.512ArgThr: 2.512 ± 0.046	4.646ArgVal: 4.646 ± 0.069	1.112ArgTrp: 1.112 ± 0.03	1.989ArgTyr: 1.989 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	6.645SerAla: 6.645 ± 0.09	0.48SerCys: 0.48 ± 0.021	3.224SerAsp: 3.224 ± 0.051	3.345SerGlu: 3.345 ± 0.071	1.757SerPhe: 1.757 ± 0.032	5.224SerGly: 5.224 ± 0.071	1.408SerHis: 1.408 ± 0.031	2.516SerIle: 2.516 ± 0.052	1.684SerLys: 1.684 ± 0.037	5.521SerLeu: 5.521 ± 0.072	1.466SerMet: 1.466 ± 0.039	1.524SerAsn: 1.524 ± 0.04	2.534SerPro: 2.534 ± 0.049	2.259SerGln: 2.259 ± 0.038	3.333SerArg: 3.333 ± 0.049	2.866SerSer: 2.866 ± 0.064	2.182SerThr: 2.182 ± 0.053	4.0SerVal: 4.0 ± 0.061	0.775SerTrp: 0.775 ± 0.03	1.121SerTyr: 1.121 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.126ThrAla: 5.126 ± 0.081	0.359ThrCys: 0.359 ± 0.016	2.431ThrAsp: 2.431 ± 0.055	2.515ThrGlu: 2.515 ± 0.054	1.598ThrPhe: 1.598 ± 0.041	4.012ThrGly: 4.012 ± 0.066	1.227ThrHis: 1.227 ± 0.027	2.27ThrIle: 2.27 ± 0.055	1.197ThrLys: 1.197 ± 0.036	6.332ThrLeu: 6.332 ± 0.076	0.916ThrMet: 0.916 ± 0.026	1.066ThrAsn: 1.066 ± 0.03	3.513ThrPro: 3.513 ± 0.057	2.062ThrGln: 2.062 ± 0.039	3.097ThrArg: 3.097 ± 0.049	2.144ThrSer: 2.144 ± 0.05	2.283ThrThr: 2.283 ± 0.06	3.224ThrVal: 3.224 ± 0.054	0.596ThrTrp: 0.596 ± 0.025	0.968ThrTyr: 0.968 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	7.854ValAla: 7.854 ± 0.091	0.703ValCys: 0.703 ± 0.021	4.222ValAsp: 4.222 ± 0.068	4.533ValGlu: 4.533 ± 0.052	2.088ValPhe: 2.088 ± 0.042	5.424ValGly: 5.424 ± 0.088	1.231ValHis: 1.231 ± 0.032	3.679ValIle: 3.679 ± 0.061	2.488ValLys: 2.488 ± 0.056	5.968ValLeu: 5.968 ± 0.075	1.946ValMet: 1.946 ± 0.038	2.198ValAsn: 2.198 ± 0.045	2.077ValPro: 2.077 ± 0.046	2.093ValGln: 2.093 ± 0.044	4.237ValArg: 4.237 ± 0.057	4.007ValSer: 4.007 ± 0.054	4.015ValThr: 4.015 ± 0.07	5.018ValVal: 5.018 ± 0.076	0.886ValTrp: 0.886 ± 0.028	1.365ValTyr: 1.365 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.217TrpAla: 1.217 ± 0.031	0.121TrpCys: 0.121 ± 0.011	0.765TrpAsp: 0.765 ± 0.027	0.795TrpGlu: 0.795 ± 0.025	0.484TrpPhe: 0.484 ± 0.018	1.006TrpGly: 1.006 ± 0.031	0.276TrpHis: 0.276 ± 0.014	0.707TrpIle: 0.707 ± 0.022	0.442TrpLys: 0.442 ± 0.018	1.796TrpLeu: 1.796 ± 0.042	0.424TrpMet: 0.424 ± 0.02	0.387TrpAsn: 0.387 ± 0.017	0.629TrpPro: 0.629 ± 0.023	0.417TrpGln: 0.417 ± 0.018	1.821TrpArg: 1.821 ± 0.049	0.927TrpSer: 0.927 ± 0.027	0.554TrpThr: 0.554 ± 0.025	0.869TrpVal: 0.869 ± 0.025	0.209TrpTrp: 0.209 ± 0.014	0.259TrpTyr: 0.259 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.563TyrAla: 2.563 ± 0.048	0.263TyrCys: 0.263 ± 0.015	1.406TyrAsp: 1.406 ± 0.034	1.241TyrGlu: 1.241 ± 0.03	0.889TyrPhe: 0.889 ± 0.027	2.045TyrGly: 2.045 ± 0.05	0.565TyrHis: 0.565 ± 0.02	0.885TyrIle: 0.885 ± 0.027	0.711TyrLys: 0.711 ± 0.023	2.562TyrLeu: 2.562 ± 0.049	0.479TyrMet: 0.479 ± 0.022	0.682TyrAsn: 0.682 ± 0.028	1.101TyrPro: 1.101 ± 0.034	0.945TyrGln: 0.945 ± 0.027	1.721TyrArg: 1.721 ± 0.037	1.05TyrSer: 1.05 ± 0.032	0.935TyrThr: 0.935 ± 0.03	1.476TyrVal: 1.476 ± 0.035	0.388TyrTrp: 0.388 ± 0.018	0.671TyrTyr: 0.671 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4001 proteins (1356533 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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