Amino acid dipepetide frequency for Blautia argi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.781AlaAla: 6.781 ± 0.135	1.159AlaCys: 1.159 ± 0.043	4.05AlaAsp: 4.05 ± 0.072	5.821AlaGlu: 5.821 ± 0.088	3.081AlaPhe: 3.081 ± 0.064	6.01AlaGly: 6.01 ± 0.098	1.079AlaHis: 1.079 ± 0.037	4.438AlaIle: 4.438 ± 0.088	4.943AlaLys: 4.943 ± 0.079	6.712AlaLeu: 6.712 ± 0.081	2.334AlaMet: 2.334 ± 0.053	2.291AlaAsn: 2.291 ± 0.053	1.856AlaPro: 1.856 ± 0.044	2.261AlaGln: 2.261 ± 0.055	2.736AlaArg: 2.736 ± 0.054	3.463AlaSer: 3.463 ± 0.072	2.701AlaThr: 2.701 ± 0.062	6.22AlaVal: 6.22 ± 0.094	0.641AlaTrp: 0.641 ± 0.03	2.765AlaTyr: 2.765 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.988CysAla: 0.988 ± 0.03	0.315CysCys: 0.315 ± 0.021	0.768CysAsp: 0.768 ± 0.035	0.979CysGlu: 0.979 ± 0.034	0.69CysPhe: 0.69 ± 0.03	1.496CysGly: 1.496 ± 0.045	0.33CysHis: 0.33 ± 0.02	1.214CysIle: 1.214 ± 0.04	0.904CysLys: 0.904 ± 0.032	1.272CysLeu: 1.272 ± 0.038	0.539CysMet: 0.539 ± 0.027	0.569CysAsn: 0.569 ± 0.028	0.621CysPro: 0.621 ± 0.032	0.507CysGln: 0.507 ± 0.026	0.823CysArg: 0.823 ± 0.033	0.987CysSer: 0.987 ± 0.036	0.814CysThr: 0.814 ± 0.03	1.038CysVal: 1.038 ± 0.037	0.126CysTrp: 0.126 ± 0.012	0.598CysTyr: 0.598 ± 0.027	0.0CysXaa: 0.0 ± 0.0
Asp	3.47AspAla: 3.47 ± 0.07	0.883AspCys: 0.883 ± 0.03	2.016AspAsp: 2.016 ± 0.064	3.897AspGlu: 3.897 ± 0.07	2.692AspPhe: 2.692 ± 0.056	3.567AspGly: 3.567 ± 0.068	0.681AspHis: 0.681 ± 0.031	4.202AspIle: 4.202 ± 0.068	3.506AspLys: 3.506 ± 0.073	4.214AspLeu: 4.214 ± 0.076	1.84AspMet: 1.84 ± 0.04	1.91AspAsn: 1.91 ± 0.052	1.342AspPro: 1.342 ± 0.041	1.022AspGln: 1.022 ± 0.036	2.186AspArg: 2.186 ± 0.049	2.961AspSer: 2.961 ± 0.057	3.024AspThr: 3.024 ± 0.074	3.252AspVal: 3.252 ± 0.08	0.573AspTrp: 0.573 ± 0.027	2.653AspTyr: 2.653 ± 0.07	0.0AspXaa: 0.0 ± 0.0
Glu	6.019GluAla: 6.019 ± 0.098	0.826GluCys: 0.826 ± 0.035	4.391GluAsp: 4.391 ± 0.078	9.466GluGlu: 9.466 ± 0.168	2.873GluPhe: 2.873 ± 0.065	4.928GluGly: 4.928 ± 0.074	1.478GluHis: 1.478 ± 0.042	6.307GluIle: 6.307 ± 0.108	8.67GluLys: 8.67 ± 0.133	7.14GluLeu: 7.14 ± 0.11	2.462GluMet: 2.462 ± 0.054	4.728GluAsn: 4.728 ± 0.088	1.854GluPro: 1.854 ± 0.046	3.226GluGln: 3.226 ± 0.069	3.576GluArg: 3.576 ± 0.072	3.456GluSer: 3.456 ± 0.066	4.023GluThr: 4.023 ± 0.067	4.877GluVal: 4.877 ± 0.077	0.683GluTrp: 0.683 ± 0.033	3.356GluTyr: 3.356 ± 0.063	0.0GluXaa: 0.0 ± 0.0
Phe	3.093PheAla: 3.093 ± 0.071	0.835PheCys: 0.835 ± 0.034	2.356PheAsp: 2.356 ± 0.058	2.717PheGlu: 2.717 ± 0.059	2.182PhePhe: 2.182 ± 0.064	3.057PheGly: 3.057 ± 0.066	0.865PheHis: 0.865 ± 0.034	2.64PheIle: 2.64 ± 0.068	1.994PheLys: 1.994 ± 0.049	4.753PheLeu: 4.753 ± 0.099	1.21PheMet: 1.21 ± 0.039	1.368PheAsn: 1.368 ± 0.041	1.556PhePro: 1.556 ± 0.043	1.695PheGln: 1.695 ± 0.044	1.764PheArg: 1.764 ± 0.046	3.091PheSer: 3.091 ± 0.066	2.267PheThr: 2.267 ± 0.053	2.893PheVal: 2.893 ± 0.059	0.524PheTrp: 0.524 ± 0.027	1.894PheTyr: 1.894 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	4.708GlyAla: 4.708 ± 0.093	1.293GlyCys: 1.293 ± 0.045	2.981GlyAsp: 2.981 ± 0.067	5.329GlyGlu: 5.329 ± 0.093	3.287GlyPhe: 3.287 ± 0.069	4.493GlyGly: 4.493 ± 0.079	1.203GlyHis: 1.203 ± 0.038	6.512GlyIle: 6.512 ± 0.1	5.975GlyLys: 5.975 ± 0.099	5.727GlyLeu: 5.727 ± 0.091	2.57GlyMet: 2.57 ± 0.064	3.251GlyAsn: 3.251 ± 0.068	1.183GlyPro: 1.183 ± 0.037	2.06GlyGln: 2.06 ± 0.054	2.967GlyArg: 2.967 ± 0.061	3.848GlySer: 3.848 ± 0.061	4.028GlyThr: 4.028 ± 0.072	4.86GlyVal: 4.86 ± 0.078	0.641GlyTrp: 0.641 ± 0.032	3.242GlyTyr: 3.242 ± 0.067	0.0GlyXaa: 0.0 ± 0.0
His	1.117HisAla: 1.117 ± 0.037	0.313HisCys: 0.313 ± 0.02	0.756HisAsp: 0.756 ± 0.031	1.088HisGlu: 1.088 ± 0.035	0.853HisPhe: 0.853 ± 0.034	1.289HisGly: 1.289 ± 0.037	0.422HisHis: 0.422 ± 0.026	1.382HisIle: 1.382 ± 0.043	0.995HisLys: 0.995 ± 0.035	1.646HisLeu: 1.646 ± 0.042	0.626HisMet: 0.626 ± 0.028	0.683HisAsn: 0.683 ± 0.027	0.719HisPro: 0.719 ± 0.033	0.6HisGln: 0.6 ± 0.027	0.818HisArg: 0.818 ± 0.032	0.938HisSer: 0.938 ± 0.035	1.076HisThr: 1.076 ± 0.035	1.097HisVal: 1.097 ± 0.037	0.185HisTrp: 0.185 ± 0.014	0.773HisTyr: 0.773 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	5.093IleAla: 5.093 ± 0.086	1.459IleCys: 1.459 ± 0.049	3.422IleAsp: 3.422 ± 0.066	4.961IleGlu: 4.961 ± 0.084	3.25IlePhe: 3.25 ± 0.073	4.763IleGly: 4.763 ± 0.091	1.352IleHis: 1.352 ± 0.035	4.438IleIle: 4.438 ± 0.086	4.022IleLys: 4.022 ± 0.067	7.516IleLeu: 7.516 ± 0.113	1.897IleMet: 1.897 ± 0.049	2.516IleAsn: 2.516 ± 0.059	3.294IlePro: 3.294 ± 0.064	2.845IleGln: 2.845 ± 0.058	3.626IleArg: 3.626 ± 0.076	4.839IleSer: 4.839 ± 0.085	3.905IleThr: 3.905 ± 0.072	4.436IleVal: 4.436 ± 0.073	0.674IleTrp: 0.674 ± 0.029	2.863IleTyr: 2.863 ± 0.066	0.0IleXaa: 0.0 ± 0.0
Lys	5.307LysAla: 5.307 ± 0.084	0.749LysCys: 0.749 ± 0.031	3.838LysAsp: 3.838 ± 0.073	8.459LysGlu: 8.459 ± 0.11	1.994LysPhe: 1.994 ± 0.056	4.776LysGly: 4.776 ± 0.086	1.057LysHis: 1.057 ± 0.037	5.25LysIle: 5.25 ± 0.075	7.156LysLys: 7.156 ± 0.09	5.507LysLeu: 5.507 ± 0.082	2.383LysMet: 2.383 ± 0.054	3.934LysAsn: 3.934 ± 0.061	2.131LysPro: 2.131 ± 0.051	2.736LysGln: 2.736 ± 0.056	3.478LysArg: 3.478 ± 0.064	3.332LysSer: 3.332 ± 0.061	4.062LysThr: 4.062 ± 0.074	4.275LysVal: 4.275 ± 0.071	0.676LysTrp: 0.676 ± 0.027	2.965LysTyr: 2.965 ± 0.059	0.0LysXaa: 0.0 ± 0.0
Leu	6.895LeuAla: 6.895 ± 0.095	1.664LeuCys: 1.664 ± 0.042	4.799LeuAsp: 4.799 ± 0.073	7.534LeuGlu: 7.534 ± 0.095	4.04LeuPhe: 4.04 ± 0.09	6.298LeuGly: 6.298 ± 0.099	1.703LeuHis: 1.703 ± 0.048	5.68LeuIle: 5.68 ± 0.105	6.788LeuLys: 6.788 ± 0.086	9.763LeuLeu: 9.763 ± 0.153	2.562LeuMet: 2.562 ± 0.051	3.74LeuAsn: 3.74 ± 0.066	3.667LeuPro: 3.667 ± 0.071	3.281LeuGln: 3.281 ± 0.064	3.626LeuArg: 3.626 ± 0.071	6.135LeuSer: 6.135 ± 0.103	4.998LeuThr: 4.998 ± 0.08	5.5LeuVal: 5.5 ± 0.079	0.812LeuTrp: 0.812 ± 0.032	3.598LeuTyr: 3.598 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	2.433MetAla: 2.433 ± 0.058	0.375MetCys: 0.375 ± 0.021	1.609MetAsp: 1.609 ± 0.045	2.957MetGlu: 2.957 ± 0.057	1.002MetPhe: 1.002 ± 0.036	2.278MetGly: 2.278 ± 0.054	0.469MetHis: 0.469 ± 0.021	2.032MetIle: 2.032 ± 0.049	2.821MetLys: 2.821 ± 0.052	2.776MetLeu: 2.776 ± 0.065	0.896MetMet: 0.896 ± 0.039	1.497MetAsn: 1.497 ± 0.041	1.127MetPro: 1.127 ± 0.032	1.068MetGln: 1.068 ± 0.034	1.241MetArg: 1.241 ± 0.043	1.551MetSer: 1.551 ± 0.045	1.663MetThr: 1.663 ± 0.043	1.976MetVal: 1.976 ± 0.047	0.239MetTrp: 0.239 ± 0.017	0.933MetTyr: 0.933 ± 0.034	0.0MetXaa: 0.0 ± 0.0
Asn	2.834AsnAla: 2.834 ± 0.064	0.595AsnCys: 0.595 ± 0.029	1.68AsnAsp: 1.68 ± 0.046	2.639AsnGlu: 2.639 ± 0.059	1.711AsnPhe: 1.711 ± 0.039	3.212AsnGly: 3.212 ± 0.069	0.79AsnHis: 0.79 ± 0.031	3.207AsnIle: 3.207 ± 0.066	2.559AsnLys: 2.559 ± 0.059	4.177AsnLeu: 4.177 ± 0.07	1.373AsnMet: 1.373 ± 0.043	1.595AsnAsn: 1.595 ± 0.064	2.2AsnPro: 2.2 ± 0.049	1.676AsnGln: 1.676 ± 0.039	2.17AsnArg: 2.17 ± 0.052	2.264AsnSer: 2.264 ± 0.057	2.435AsnThr: 2.435 ± 0.06	2.591AsnVal: 2.591 ± 0.055	0.43AsnTrp: 0.43 ± 0.023	1.866AsnTyr: 1.866 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	2.218ProAla: 2.218 ± 0.052	0.463ProCys: 0.463 ± 0.025	2.086ProAsp: 2.086 ± 0.054	3.444ProGlu: 3.444 ± 0.087	1.549ProPhe: 1.549 ± 0.046	2.372ProGly: 2.372 ± 0.06	0.642ProHis: 0.642 ± 0.023	1.91ProIle: 1.91 ± 0.056	2.049ProLys: 2.049 ± 0.049	2.939ProLeu: 2.939 ± 0.059	0.879ProMet: 0.879 ± 0.036	1.197ProAsn: 1.197 ± 0.039	0.698ProPro: 0.698 ± 0.026	1.125ProGln: 1.125 ± 0.036	1.007ProArg: 1.007 ± 0.036	1.672ProSer: 1.672 ± 0.045	1.373ProThr: 1.373 ± 0.044	3.024ProVal: 3.024 ± 0.058	0.344ProTrp: 0.344 ± 0.02	1.474ProTyr: 1.474 ± 0.043	0.0ProXaa: 0.0 ± 0.0
Gln	2.445GlnAla: 2.445 ± 0.052	0.354GlnCys: 0.354 ± 0.021	1.624GlnAsp: 1.624 ± 0.045	3.581GlnGlu: 3.581 ± 0.071	1.178GlnPhe: 1.178 ± 0.04	2.372GlnGly: 2.372 ± 0.053	0.5GlnHis: 0.5 ± 0.024	2.676GlnIle: 2.676 ± 0.054	3.372GlnLys: 3.372 ± 0.063	2.721GlnLeu: 2.721 ± 0.06	1.181GlnMet: 1.181 ± 0.036	1.74GlnAsn: 1.74 ± 0.048	0.948GlnPro: 0.948 ± 0.037	1.297GlnGln: 1.297 ± 0.041	1.492GlnArg: 1.492 ± 0.044	1.574GlnSer: 1.574 ± 0.041	1.823GlnThr: 1.823 ± 0.048	2.306GlnVal: 2.306 ± 0.058	0.353GlnTrp: 0.353 ± 0.019	1.472GlnTyr: 1.472 ± 0.043	0.0GlnXaa: 0.0 ± 0.0
Arg	2.579ArgAla: 2.579 ± 0.062	0.586ArgCys: 0.586 ± 0.026	1.966ArgAsp: 1.966 ± 0.05	4.465ArgGlu: 4.465 ± 0.084	1.834ArgPhe: 1.834 ± 0.041	2.521ArgGly: 2.521 ± 0.05	0.746ArgHis: 0.746 ± 0.032	3.563ArgIle: 3.563 ± 0.061	3.918ArgLys: 3.918 ± 0.077	3.794ArgLeu: 3.794 ± 0.069	1.479ArgMet: 1.479 ± 0.042	2.133ArgAsn: 2.133 ± 0.048	1.189ArgPro: 1.189 ± 0.035	1.787ArgGln: 1.787 ± 0.049	2.239ArgArg: 2.239 ± 0.068	1.973ArgSer: 1.973 ± 0.054	2.239ArgThr: 2.239 ± 0.051	2.627ArgVal: 2.627 ± 0.049	0.332ArgTrp: 0.332 ± 0.019	1.82ArgTyr: 1.82 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	3.806SerAla: 3.806 ± 0.071	0.957SerCys: 0.957 ± 0.037	2.692SerAsp: 2.692 ± 0.065	3.774SerGlu: 3.774 ± 0.063	2.813SerPhe: 2.813 ± 0.073	4.396SerGly: 4.396 ± 0.075	1.012SerHis: 1.012 ± 0.036	3.89SerIle: 3.89 ± 0.077	3.149SerLys: 3.149 ± 0.061	5.274SerLeu: 5.274 ± 0.088	1.922SerMet: 1.922 ± 0.051	1.947SerAsn: 1.947 ± 0.052	1.811SerPro: 1.811 ± 0.049	1.901SerGln: 1.901 ± 0.047	2.721SerArg: 2.721 ± 0.058	3.348SerSer: 3.348 ± 0.075	2.515SerThr: 2.515 ± 0.055	4.266SerVal: 4.266 ± 0.075	0.619SerTrp: 0.619 ± 0.028	2.487SerTyr: 2.487 ± 0.056	0.0SerXaa: 0.0 ± 0.0
Thr	4.169ThrAla: 4.169 ± 0.076	0.698ThrCys: 0.698 ± 0.029	2.974ThrAsp: 2.974 ± 0.061	4.36ThrGlu: 4.36 ± 0.081	2.116ThrPhe: 2.116 ± 0.048	4.588ThrGly: 4.588 ± 0.086	0.912ThrHis: 0.912 ± 0.038	3.535ThrIle: 3.535 ± 0.077	3.107ThrLys: 3.107 ± 0.072	4.82ThrLeu: 4.82 ± 0.074	1.435ThrMet: 1.435 ± 0.04	1.814ThrAsn: 1.814 ± 0.048	2.134ThrPro: 2.134 ± 0.054	1.552ThrGln: 1.552 ± 0.045	1.943ThrArg: 1.943 ± 0.042	2.65ThrSer: 2.65 ± 0.055	2.493ThrThr: 2.493 ± 0.054	4.164ThrVal: 4.164 ± 0.081	0.511ThrTrp: 0.511 ± 0.025	2.14ThrTyr: 2.14 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	4.166ValAla: 4.166 ± 0.085	1.249ValCys: 1.249 ± 0.042	3.171ValAsp: 3.171 ± 0.07	4.723ValGlu: 4.723 ± 0.079	3.189ValPhe: 3.189 ± 0.072	4.003ValGly: 4.003 ± 0.069	1.068ValHis: 1.068 ± 0.041	4.741ValIle: 4.741 ± 0.081	4.874ValLys: 4.874 ± 0.075	7.235ValLeu: 7.235 ± 0.107	1.995ValMet: 1.995 ± 0.052	2.76ValAsn: 2.76 ± 0.064	2.423ValPro: 2.423 ± 0.056	2.288ValGln: 2.288 ± 0.051	2.849ValArg: 2.849 ± 0.058	4.413ValSer: 4.413 ± 0.077	3.867ValThr: 3.867 ± 0.083	4.542ValVal: 4.542 ± 0.084	0.681ValTrp: 0.681 ± 0.027	2.789ValTyr: 2.789 ± 0.06	0.0ValXaa: 0.0 ± 0.0
Trp	0.559TrpAla: 0.559 ± 0.027	0.171TrpCys: 0.171 ± 0.015	0.516TrpAsp: 0.516 ± 0.025	0.82TrpGlu: 0.82 ± 0.035	0.413TrpPhe: 0.413 ± 0.023	0.677TrpGly: 0.677 ± 0.028	0.163TrpHis: 0.163 ± 0.015	0.742TrpIle: 0.742 ± 0.032	0.834TrpLys: 0.834 ± 0.027	0.942TrpLeu: 0.942 ± 0.034	0.171TrpMet: 0.171 ± 0.014	0.583TrpAsn: 0.583 ± 0.03	0.179TrpPro: 0.179 ± 0.014	0.409TrpGln: 0.409 ± 0.023	0.391TrpArg: 0.391 ± 0.02	0.491TrpSer: 0.491 ± 0.024	0.46TrpThr: 0.46 ± 0.021	0.501TrpVal: 0.501 ± 0.024	0.101TrpTrp: 0.101 ± 0.012	0.422TrpTyr: 0.422 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.66TyrAla: 2.66 ± 0.058	0.636TyrCys: 0.636 ± 0.027	2.198TyrAsp: 2.198 ± 0.056	3.321TyrGlu: 3.321 ± 0.061	2.01TyrPhe: 2.01 ± 0.059	3.059TyrGly: 3.059 ± 0.057	0.903TyrHis: 0.903 ± 0.031	2.813TyrIle: 2.813 ± 0.068	2.428TyrLys: 2.428 ± 0.056	4.157TyrLeu: 4.157 ± 0.08	1.187TyrMet: 1.187 ± 0.039	1.747TyrAsn: 1.747 ± 0.053	1.535TyrPro: 1.535 ± 0.045	1.671TyrGln: 1.671 ± 0.044	2.141TyrArg: 2.141 ± 0.054	2.315TyrSer: 2.315 ± 0.054	2.348TyrThr: 2.348 ± 0.052	2.579TyrVal: 2.579 ± 0.058	0.402TyrTrp: 0.402 ± 0.022	1.93TyrTyr: 1.93 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2737 proteins (869576 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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