Amino acid dipepetide frequency for Alces alces faeces associated microvirus MP3 6497

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.734AlaAla: 0.734 ± 0.777
1.468AlaCys: 1.468 ± 0.507
5.14AlaAsp: 5.14 ± 2.509
2.203AlaGlu: 2.203 ± 0.415
5.874AlaPhe: 5.874 ± 1.162
3.671AlaGly: 3.671 ± 2.845
0.734AlaHis: 0.734 ± 0.642
2.937AlaIle: 2.937 ± 1.233
0.734AlaLys: 0.734 ± 0.642
5.874AlaLeu: 5.874 ± 1.261
1.468AlaMet: 1.468 ± 1.555
3.671AlaAsn: 3.671 ± 0.563
4.405AlaPro: 4.405 ± 2.85
3.671AlaGln: 3.671 ± 1.322
5.874AlaArg: 5.874 ± 1.535
5.874AlaSer: 5.874 ± 0.275
0.734AlaThr: 0.734 ± 0.475
1.468AlaVal: 1.468 ± 0.507
0.734AlaTrp: 0.734 ± 0.777
5.14AlaTyr: 5.14 ± 0.736
0.0AlaXaa: 0.0 ± 0.0
Cys
2.937CysAla: 2.937 ± 1.671
0.734CysCys: 0.734 ± 0.475
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.734CysPhe: 0.734 ± 0.475
1.468CysGly: 1.468 ± 1.284
0.734CysHis: 0.734 ± 0.642
0.734CysIle: 0.734 ± 0.475
2.203CysLys: 2.203 ± 1.926
0.734CysLeu: 0.734 ± 0.642
0.734CysMet: 0.734 ± 0.475
0.734CysAsn: 0.734 ± 0.475
0.734CysPro: 0.734 ± 0.642
0.734CysGln: 0.734 ± 0.642
1.468CysArg: 1.468 ± 0.507
0.734CysSer: 0.734 ± 0.475
0.734CysThr: 0.734 ± 0.475
0.734CysVal: 0.734 ± 0.475
0.0CysTrp: 0.0 ± 0.0
0.734CysTyr: 0.734 ± 0.642
0.0CysXaa: 0.0 ± 0.0
Asp
1.468AspAla: 1.468 ± 0.616
1.468AspCys: 1.468 ± 0.95
2.203AspAsp: 2.203 ± 0.744
0.734AspGlu: 0.734 ± 0.475
7.342AspPhe: 7.342 ± 1.423
2.203AspGly: 2.203 ± 1.055
0.0AspHis: 0.0 ± 0.0
3.671AspIle: 3.671 ± 1.582
3.671AspLys: 3.671 ± 1.293
4.405AspLeu: 4.405 ± 2.038
4.405AspMet: 4.405 ± 2.677
6.608AspAsn: 6.608 ± 0.904
0.734AspPro: 0.734 ± 0.475
1.468AspGln: 1.468 ± 0.882
3.671AspArg: 3.671 ± 1.582
6.608AspSer: 6.608 ± 0.369
4.405AspThr: 4.405 ± 1.604
5.874AspVal: 5.874 ± 0.917
0.734AspTrp: 0.734 ± 0.475
9.545AspTyr: 9.545 ± 1.997
0.0AspXaa: 0.0 ± 0.0
Glu
2.937GluAla: 2.937 ± 3.109
0.0GluCys: 0.0 ± 0.0
2.937GluAsp: 2.937 ± 0.138
0.734GluGlu: 0.734 ± 0.475
1.468GluPhe: 1.468 ± 0.507
1.468GluGly: 1.468 ± 0.95
1.468GluHis: 1.468 ± 0.507
1.468GluIle: 1.468 ± 0.882
4.405GluLys: 4.405 ± 2.645
3.671GluLeu: 3.671 ± 1.182
1.468GluMet: 1.468 ± 0.95
5.14GluAsn: 5.14 ± 0.916
1.468GluPro: 1.468 ± 0.95
0.734GluGln: 0.734 ± 0.777
2.203GluArg: 2.203 ± 1.533
1.468GluSer: 1.468 ± 0.507
2.203GluThr: 2.203 ± 1.425
1.468GluVal: 1.468 ± 1.284
0.0GluTrp: 0.0 ± 0.0
3.671GluTyr: 3.671 ± 1.526
0.0GluXaa: 0.0 ± 0.0
Phe
2.203PheAla: 2.203 ± 0.744
0.0PheCys: 0.0 ± 0.0
2.937PheAsp: 2.937 ± 1.141
2.203PheGlu: 2.203 ± 0.415
1.468PhePhe: 1.468 ± 0.507
7.342PheGly: 7.342 ± 3.422
1.468PheHis: 1.468 ± 0.507
1.468PheIle: 1.468 ± 0.616
2.203PheLys: 2.203 ± 1.332
1.468PheLeu: 1.468 ± 0.882
1.468PheMet: 1.468 ± 1.284
3.671PheAsn: 3.671 ± 1.182
3.671PhePro: 3.671 ± 2.375
2.937PheGln: 2.937 ± 0.888
2.937PheArg: 2.937 ± 1.9
4.405PheSer: 4.405 ± 0.415
3.671PheThr: 3.671 ± 1.182
3.671PheVal: 3.671 ± 1.526
0.0PheTrp: 0.0 ± 0.0
1.468PheTyr: 1.468 ± 0.95
0.0PheXaa: 0.0 ± 0.0
Gly
2.937GlyAla: 2.937 ± 2.077
0.0GlyCys: 0.0 ± 0.0
5.874GlyAsp: 5.874 ± 0.275
3.671GlyGlu: 3.671 ± 2.377
2.937GlyPhe: 2.937 ± 1.671
2.937GlyGly: 2.937 ± 1.014
0.734GlyHis: 0.734 ± 0.475
4.405GlyIle: 4.405 ± 1.033
1.468GlyLys: 1.468 ± 0.616
8.076GlyLeu: 8.076 ± 2.661
2.937GlyMet: 2.937 ± 1.041
3.671GlyAsn: 3.671 ± 1.322
0.0GlyPro: 0.0 ± 0.0
2.203GlyGln: 2.203 ± 0.415
2.203GlyArg: 2.203 ± 0.744
6.608GlySer: 6.608 ± 1.623
5.14GlyThr: 5.14 ± 2.509
2.203GlyVal: 2.203 ± 0.744
0.734GlyTrp: 0.734 ± 0.475
2.937GlyTyr: 2.937 ± 1.014
0.0GlyXaa: 0.0 ± 0.0
His
1.468HisAla: 1.468 ± 0.507
0.734HisCys: 0.734 ± 0.642
1.468HisAsp: 1.468 ± 0.616
0.734HisGlu: 0.734 ± 0.642
2.203HisPhe: 2.203 ± 0.744
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.734HisIle: 0.734 ± 0.642
0.734HisLys: 0.734 ± 0.642
0.734HisLeu: 0.734 ± 0.642
0.0HisMet: 0.0 ± 0.0
4.405HisAsn: 4.405 ± 0.735
0.0HisPro: 0.0 ± 0.0
0.734HisGln: 0.734 ± 0.777
0.0HisArg: 0.0 ± 0.0
1.468HisSer: 1.468 ± 1.284
0.734HisThr: 0.734 ± 0.475
0.734HisVal: 0.734 ± 0.475
0.0HisTrp: 0.0 ± 0.0
0.734HisTyr: 0.734 ± 0.642
0.0HisXaa: 0.0 ± 0.0
Ile
3.671IleAla: 3.671 ± 1.322
0.0IleCys: 0.0 ± 0.0
3.671IleAsp: 3.671 ± 1.905
4.405IleGlu: 4.405 ± 1.522
2.937IlePhe: 2.937 ± 0.888
5.14IleGly: 5.14 ± 1.91
2.203IleHis: 2.203 ± 0.415
2.203IleIle: 2.203 ± 1.055
2.203IleLys: 2.203 ± 1.32
5.14IleLeu: 5.14 ± 0.396
0.734IleMet: 0.734 ± 0.777
1.468IleAsn: 1.468 ± 0.507
5.14IlePro: 5.14 ± 1.867
1.468IleGln: 1.468 ± 0.616
4.405IleArg: 4.405 ± 1.695
3.671IleSer: 3.671 ± 0.832
2.937IleThr: 2.937 ± 1.014
3.671IleVal: 3.671 ± 0.505
0.0IleTrp: 0.0 ± 0.0
2.203IleTyr: 2.203 ± 0.744
0.0IleXaa: 0.0 ± 0.0
Lys
4.405LysAla: 4.405 ± 1.999
0.734LysCys: 0.734 ± 0.642
2.937LysAsp: 2.937 ± 0.888
2.937LysGlu: 2.937 ± 1.138
3.671LysPhe: 3.671 ± 1.493
3.671LysGly: 3.671 ± 1.493
0.0LysHis: 0.0 ± 0.0
3.671LysIle: 3.671 ± 2.166
6.608LysLys: 6.608 ± 3.38
4.405LysLeu: 4.405 ± 2.12
2.203LysMet: 2.203 ± 2.061
2.937LysAsn: 2.937 ± 1.138
0.734LysPro: 0.734 ± 0.777
0.734LysGln: 0.734 ± 0.642
1.468LysArg: 1.468 ± 0.882
2.937LysSer: 2.937 ± 0.138
1.468LysThr: 1.468 ± 0.507
0.0LysVal: 0.0 ± 0.0
1.468LysTrp: 1.468 ± 0.882
2.203LysTyr: 2.203 ± 1.332
0.0LysXaa: 0.0 ± 0.0
Leu
1.468LeuAla: 1.468 ± 0.882
0.734LeuCys: 0.734 ± 0.642
5.874LeuAsp: 5.874 ± 1.167
3.671LeuGlu: 3.671 ± 1.322
2.937LeuPhe: 2.937 ± 1.014
3.671LeuGly: 3.671 ± 1.322
2.203LeuHis: 2.203 ± 1.055
5.14LeuIle: 5.14 ± 0.396
5.14LeuLys: 5.14 ± 0.736
4.405LeuLeu: 4.405 ± 1.147
1.468LeuMet: 1.468 ± 0.616
6.608LeuAsn: 6.608 ± 2.164
6.608LeuPro: 6.608 ± 0.369
4.405LeuGln: 4.405 ± 2.677
4.405LeuArg: 4.405 ± 2.12
8.811LeuSer: 8.811 ± 2.217
5.874LeuThr: 5.874 ± 0.773
1.468LeuVal: 1.468 ± 0.95
2.203LeuTrp: 2.203 ± 0.415
1.468LeuTyr: 1.468 ± 0.507
0.0LeuXaa: 0.0 ± 0.0
Met
5.14MetAla: 5.14 ± 1.404
0.0MetCys: 0.0 ± 0.0
1.468MetAsp: 1.468 ± 1.284
1.468MetGlu: 1.468 ± 1.284
1.468MetPhe: 1.468 ± 0.507
2.203MetGly: 2.203 ± 1.32
1.468MetHis: 1.468 ± 1.555
0.734MetIle: 0.734 ± 0.475
0.0MetLys: 0.0 ± 0.0
0.734MetLeu: 0.734 ± 0.777
0.0MetMet: 0.0 ± 0.0
2.203MetAsn: 2.203 ± 2.332
0.734MetPro: 0.734 ± 0.777
0.734MetGln: 0.734 ± 0.475
1.468MetArg: 1.468 ± 0.616
5.874MetSer: 5.874 ± 1.349
0.734MetThr: 0.734 ± 0.475
0.734MetVal: 0.734 ± 0.475
0.0MetTrp: 0.0 ± 0.0
1.468MetTyr: 1.468 ± 0.616
0.0MetXaa: 0.0 ± 0.0
Asn
3.671AsnAla: 3.671 ± 0.563
1.468AsnCys: 1.468 ± 0.507
5.14AsnAsp: 5.14 ± 1.404
2.937AsnGlu: 2.937 ± 1.9
0.0AsnPhe: 0.0 ± 0.0
7.342AsnGly: 7.342 ± 1.664
1.468AsnHis: 1.468 ± 1.284
5.874AsnIle: 5.874 ± 1.776
3.671AsnLys: 3.671 ± 0.832
8.811AsnLeu: 8.811 ± 2.581
2.203AsnMet: 2.203 ± 1.533
8.076AsnAsn: 8.076 ± 0.753
3.671AsnPro: 3.671 ± 1.554
0.734AsnGln: 0.734 ± 0.777
2.203AsnArg: 2.203 ± 1.425
3.671AsnSer: 3.671 ± 2.845
3.671AsnThr: 3.671 ± 1.554
3.671AsnVal: 3.671 ± 1.554
1.468AsnTrp: 1.468 ± 0.95
5.14AsnTyr: 5.14 ± 1.789
0.0AsnXaa: 0.0 ± 0.0
Pro
4.405ProAla: 4.405 ± 2.038
0.734ProCys: 0.734 ± 0.642
3.671ProAsp: 3.671 ± 1.582
2.203ProGlu: 2.203 ± 1.425
2.937ProPhe: 2.937 ± 1.9
0.734ProGly: 0.734 ± 0.475
0.734ProHis: 0.734 ± 0.475
5.874ProIle: 5.874 ± 1.167
2.937ProLys: 2.937 ± 2.567
5.14ProLeu: 5.14 ± 1.527
0.734ProMet: 0.734 ± 0.475
2.937ProAsn: 2.937 ± 1.9
0.734ProPro: 0.734 ± 0.475
0.734ProGln: 0.734 ± 0.777
0.734ProArg: 0.734 ± 0.475
2.203ProSer: 2.203 ± 0.744
2.937ProThr: 2.937 ± 1.141
2.937ProVal: 2.937 ± 0.888
0.0ProTrp: 0.0 ± 0.0
2.203ProTyr: 2.203 ± 1.425
0.0ProXaa: 0.0 ± 0.0
Gln
1.468GlnAla: 1.468 ± 0.507
0.734GlnCys: 0.734 ± 0.475
2.203GlnAsp: 2.203 ± 0.779
0.0GlnGlu: 0.0 ± 0.0
2.203GlnPhe: 2.203 ± 0.415
2.937GlnGly: 2.937 ± 0.138
0.734GlnHis: 0.734 ± 0.777
2.203GlnIle: 2.203 ± 1.32
2.937GlnLys: 2.937 ± 2.265
2.203GlnLeu: 2.203 ± 1.055
0.0GlnMet: 0.0 ± 0.0
3.671GlnAsn: 3.671 ± 1.905
0.734GlnPro: 0.734 ± 0.642
1.468GlnGln: 1.468 ± 1.555
2.937GlnArg: 2.937 ± 1.233
3.671GlnSer: 3.671 ± 1.905
2.203GlnThr: 2.203 ± 2.332
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.734GlnTyr: 0.734 ± 0.475
0.0GlnXaa: 0.0 ± 0.0
Arg
2.937ArgAla: 2.937 ± 1.763
1.468ArgCys: 1.468 ± 1.284
4.405ArgAsp: 4.405 ± 2.12
2.937ArgGlu: 2.937 ± 1.763
2.937ArgPhe: 2.937 ± 1.014
3.671ArgGly: 3.671 ± 1.582
2.203ArgHis: 2.203 ± 1.055
1.468ArgIle: 1.468 ± 0.882
1.468ArgLys: 1.468 ± 0.616
2.937ArgLeu: 2.937 ± 0.138
2.937ArgMet: 2.937 ± 1.141
2.937ArgAsn: 2.937 ± 1.134
3.671ArgPro: 3.671 ± 2.301
1.468ArgGln: 1.468 ± 0.95
3.671ArgArg: 3.671 ± 1.582
2.937ArgSer: 2.937 ± 1.141
2.937ArgThr: 2.937 ± 0.888
2.937ArgVal: 2.937 ± 1.9
0.734ArgTrp: 0.734 ± 0.777
2.937ArgTyr: 2.937 ± 1.014
0.0ArgXaa: 0.0 ± 0.0
Ser
6.608SerAla: 6.608 ± 2.078
1.468SerCys: 1.468 ± 0.95
8.076SerAsp: 8.076 ± 1.053
3.671SerGlu: 3.671 ± 0.505
2.203SerPhe: 2.203 ± 0.415
5.14SerGly: 5.14 ± 1.886
0.0SerHis: 0.0 ± 0.0
5.14SerIle: 5.14 ± 1.404
2.937SerLys: 2.937 ± 0.888
9.545SerLeu: 9.545 ± 1.674
0.0SerMet: 0.0 ± 0.523
4.405SerAsn: 4.405 ± 1.849
2.937SerPro: 2.937 ± 1.134
0.734SerGln: 0.734 ± 0.777
2.937SerArg: 2.937 ± 1.671
9.545SerSer: 9.545 ± 2.474
3.671SerThr: 3.671 ± 1.322
8.811SerVal: 8.811 ± 4.851
0.734SerTrp: 0.734 ± 0.777
3.671SerTyr: 3.671 ± 0.505
0.0SerXaa: 0.0 ± 0.0
Thr
8.811ThrAla: 8.811 ± 3.401
0.0ThrCys: 0.0 ± 0.0
2.937ThrAsp: 2.937 ± 1.141
1.468ThrGlu: 1.468 ± 1.555
1.468ThrPhe: 1.468 ± 0.616
2.937ThrGly: 2.937 ± 1.141
0.0ThrHis: 0.0 ± 0.0
2.937ThrIle: 2.937 ± 1.138
1.468ThrLys: 1.468 ± 0.507
5.14ThrLeu: 5.14 ± 0.396
2.937ThrMet: 2.937 ± 1.233
4.405ThrAsn: 4.405 ± 1.849
3.671ThrPro: 3.671 ± 1.582
1.468ThrGln: 1.468 ± 0.95
5.874ThrArg: 5.874 ± 2.574
1.468ThrSer: 1.468 ± 0.95
2.937ThrThr: 2.937 ± 0.138
4.405ThrVal: 4.405 ± 0.415
0.0ThrTrp: 0.0 ± 0.0
5.14ThrTyr: 5.14 ± 1.867
0.0ThrXaa: 0.0 ± 0.0
Val
1.468ValAla: 1.468 ± 0.616
1.468ValCys: 1.468 ± 0.507
5.14ValAsp: 5.14 ± 1.66
1.468ValGlu: 1.468 ± 0.95
2.203ValPhe: 2.203 ± 1.425
2.203ValGly: 2.203 ± 1.425
1.468ValHis: 1.468 ± 0.95
2.203ValIle: 2.203 ± 0.779
0.734ValLys: 0.734 ± 0.777
1.468ValLeu: 1.468 ± 1.284
0.0ValMet: 0.0 ± 0.0
3.671ValAsn: 3.671 ± 0.563
4.405ValPro: 4.405 ± 1.489
0.734ValGln: 0.734 ± 0.642
2.937ValArg: 2.937 ± 1.671
5.14ValSer: 5.14 ± 1.506
8.076ValThr: 8.076 ± 3.004
1.468ValVal: 1.468 ± 0.507
0.734ValTrp: 0.734 ± 0.642
1.468ValTyr: 1.468 ± 0.95
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.734TrpAsp: 0.734 ± 0.777
0.734TrpGlu: 0.734 ± 0.475
0.734TrpPhe: 0.734 ± 0.475
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.734TrpIle: 0.734 ± 0.475
1.468TrpLys: 1.468 ± 1.284
0.734TrpLeu: 0.734 ± 0.475
0.0TrpMet: 0.0 ± 0.0
1.468TrpAsn: 1.468 ± 0.882
0.0TrpPro: 0.0 ± 0.0
0.734TrpGln: 0.734 ± 0.777
1.468TrpArg: 1.468 ± 0.616
2.937TrpSer: 2.937 ± 0.138
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.671TyrAla: 3.671 ± 0.563
4.405TyrCys: 4.405 ± 2.937
4.405TyrAsp: 4.405 ± 2.11
2.203TyrGlu: 2.203 ± 1.055
2.937TyrPhe: 2.937 ± 0.888
2.937TyrGly: 2.937 ± 0.138
0.0TyrHis: 0.0 ± 0.0
3.671TyrIle: 3.671 ± 1.526
2.203TyrLys: 2.203 ± 0.779
2.937TyrLeu: 2.937 ± 1.014
2.203TyrMet: 2.203 ± 0.415
2.203TyrAsn: 2.203 ± 0.744
1.468TyrPro: 1.468 ± 0.507
5.14TyrGln: 5.14 ± 2.38
0.734TyrArg: 0.734 ± 0.475
2.937TyrSer: 2.937 ± 1.141
4.405TyrThr: 4.405 ± 2.038
2.203TyrVal: 2.203 ± 0.744
2.203TyrTrp: 2.203 ± 0.744
2.937TyrTyr: 2.937 ± 1.141
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1363 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski