Amino acid dipepetide frequency for Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.826AlaAla: 9.826 ± 0.173	1.202AlaCys: 1.202 ± 0.051	4.752AlaAsp: 4.752 ± 0.1	6.345AlaGlu: 6.345 ± 0.11	3.658AlaPhe: 3.658 ± 0.075	8.001AlaGly: 8.001 ± 0.133	1.655AlaHis: 1.655 ± 0.052	5.946AlaIle: 5.946 ± 0.094	4.411AlaLys: 4.411 ± 0.098	9.85AlaLeu: 9.85 ± 0.151	2.951AlaMet: 2.951 ± 0.07	2.453AlaAsn: 2.453 ± 0.071	3.422AlaPro: 3.422 ± 0.086	2.544AlaGln: 2.544 ± 0.06	5.368AlaArg: 5.368 ± 0.099	5.711AlaSer: 5.711 ± 0.103	4.351AlaThr: 4.351 ± 0.086	6.744AlaVal: 6.744 ± 0.13	1.17AlaTrp: 1.17 ± 0.048	2.062AlaTyr: 2.062 ± 0.054	0.002AlaXaa: 0.002 ± 0.002
Cys	0.876CysAla: 0.876 ± 0.044	0.239CysCys: 0.239 ± 0.021	0.654CysAsp: 0.654 ± 0.034	0.572CysGlu: 0.572 ± 0.031	0.532CysPhe: 0.532 ± 0.027	1.165CysGly: 1.165 ± 0.046	0.298CysHis: 0.298 ± 0.021	0.654CysIle: 0.654 ± 0.033	0.434CysLys: 0.434 ± 0.026	0.941CysLeu: 0.941 ± 0.043	0.26CysMet: 0.26 ± 0.022	0.451CysAsn: 0.451 ± 0.031	0.675CysPro: 0.675 ± 0.038	0.348CysGln: 0.348 ± 0.025	0.877CysArg: 0.877 ± 0.043	0.793CysSer: 0.793 ± 0.044	0.537CysThr: 0.537 ± 0.034	0.679CysVal: 0.679 ± 0.034	0.111CysTrp: 0.111 ± 0.014	0.374CysTyr: 0.374 ± 0.026	0.0CysXaa: 0.0 ± 0.0
Asp	4.82AspAla: 4.82 ± 0.104	0.562AspCys: 0.562 ± 0.029	2.563AspAsp: 2.563 ± 0.07	3.982AspGlu: 3.982 ± 0.1	2.445AspPhe: 2.445 ± 0.062	3.905AspGly: 3.905 ± 0.077	1.126AspHis: 1.126 ± 0.046	3.314AspIle: 3.314 ± 0.083	2.548AspLys: 2.548 ± 0.068	4.958AspLeu: 4.958 ± 0.099	1.327AspMet: 1.327 ± 0.044	1.626AspAsn: 1.626 ± 0.052	2.603AspPro: 2.603 ± 0.06	1.365AspGln: 1.365 ± 0.052	3.376AspArg: 3.376 ± 0.085	2.81AspSer: 2.81 ± 0.06	2.421AspThr: 2.421 ± 0.056	3.463AspVal: 3.463 ± 0.07	0.63AspTrp: 0.63 ± 0.034	1.784AspTyr: 1.784 ± 0.054	0.0AspXaa: 0.0 ± 0.0
Glu	6.834GluAla: 6.834 ± 0.141	0.678GluCys: 0.678 ± 0.038	2.174GluAsp: 2.174 ± 0.061	4.813GluGlu: 4.813 ± 0.095	2.537GluPhe: 2.537 ± 0.07	4.082GluGly: 4.082 ± 0.08	1.655GluHis: 1.655 ± 0.051	4.365GluIle: 4.365 ± 0.095	4.559GluLys: 4.559 ± 0.09	7.227GluLeu: 7.227 ± 0.113	1.829GluMet: 1.829 ± 0.05	2.362GluAsn: 2.362 ± 0.073	2.73GluPro: 2.73 ± 0.07	2.476GluGln: 2.476 ± 0.061	4.57GluArg: 4.57 ± 0.1	3.738GluSer: 3.738 ± 0.078	3.51GluThr: 3.51 ± 0.071	4.413GluVal: 4.413 ± 0.097	0.678GluTrp: 0.678 ± 0.036	1.746GluTyr: 1.746 ± 0.061	0.0GluXaa: 0.0 ± 0.0
Phe	3.849PheAla: 3.849 ± 0.094	0.594PheCys: 0.594 ± 0.033	2.844PheAsp: 2.844 ± 0.075	2.712PheGlu: 2.712 ± 0.065	2.22PhePhe: 2.22 ± 0.076	3.719PheGly: 3.719 ± 0.08	0.899PheHis: 0.899 ± 0.039	2.565PheIle: 2.565 ± 0.066	1.598PheLys: 1.598 ± 0.05	3.849PheLeu: 3.849 ± 0.085	1.202PheMet: 1.202 ± 0.05	1.441PheAsn: 1.441 ± 0.051	1.822PhePro: 1.822 ± 0.061	1.067PheGln: 1.067 ± 0.043	2.741PheArg: 2.741 ± 0.058	3.324PheSer: 3.324 ± 0.086	2.358PheThr: 2.358 ± 0.06	2.947PheVal: 2.947 ± 0.08	0.567PheTrp: 0.567 ± 0.03	1.287PheTyr: 1.287 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	6.193GlyAla: 6.193 ± 0.097	0.982GlyCys: 0.982 ± 0.039	3.742GlyAsp: 3.742 ± 0.072	4.718GlyGlu: 4.718 ± 0.096	3.662GlyPhe: 3.662 ± 0.074	5.858GlyGly: 5.858 ± 0.125	1.686GlyHis: 1.686 ± 0.056	5.433GlyIle: 5.433 ± 0.101	4.844GlyLys: 4.844 ± 0.097	7.108GlyLeu: 7.108 ± 0.115	2.426GlyMet: 2.426 ± 0.065	2.601GlyAsn: 2.601 ± 0.052	2.101GlyPro: 2.101 ± 0.057	2.247GlyGln: 2.247 ± 0.056	4.457GlyArg: 4.457 ± 0.088	4.749GlySer: 4.749 ± 0.097	3.951GlyThr: 3.951 ± 0.094	5.515GlyVal: 5.515 ± 0.097	0.96GlyTrp: 0.96 ± 0.04	2.589GlyTyr: 2.589 ± 0.067	0.0GlyXaa: 0.0 ± 0.0
His	1.739HisAla: 1.739 ± 0.053	0.334HisCys: 0.334 ± 0.026	1.248HisAsp: 1.248 ± 0.045	1.414HisGlu: 1.414 ± 0.048	0.996HisPhe: 0.996 ± 0.038	1.656HisGly: 1.656 ± 0.054	0.648HisHis: 0.648 ± 0.03	1.161HisIle: 1.161 ± 0.045	0.861HisLys: 0.861 ± 0.037	2.057HisLeu: 2.057 ± 0.062	0.47HisMet: 0.47 ± 0.032	0.743HisAsn: 0.743 ± 0.034	1.278HisPro: 1.278 ± 0.049	0.757HisGln: 0.757 ± 0.037	1.297HisArg: 1.297 ± 0.049	1.243HisSer: 1.243 ± 0.045	1.039HisThr: 1.039 ± 0.039	1.264HisVal: 1.264 ± 0.05	0.242HisTrp: 0.242 ± 0.022	0.766HisTyr: 0.766 ± 0.038	0.0HisXaa: 0.0 ± 0.0
Ile	6.544IleAla: 6.544 ± 0.096	0.694IleCys: 0.694 ± 0.036	4.435IleAsp: 4.435 ± 0.084	4.785IleGlu: 4.785 ± 0.09	2.513IlePhe: 2.513 ± 0.074	5.197IleGly: 5.197 ± 0.109	1.183IleHis: 1.183 ± 0.043	3.732IleIle: 3.732 ± 0.089	2.665IleLys: 2.665 ± 0.079	5.064IleLeu: 5.064 ± 0.093	1.463IleMet: 1.463 ± 0.05	2.062IleAsn: 2.062 ± 0.059	2.894IlePro: 2.894 ± 0.075	1.59IleGln: 1.59 ± 0.049	3.878IleArg: 3.878 ± 0.074	4.049IleSer: 4.049 ± 0.089	3.281IleThr: 3.281 ± 0.077	4.723IleVal: 4.723 ± 0.098	0.456IleTrp: 0.456 ± 0.025	1.667IleTyr: 1.667 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	5.067LysAla: 5.067 ± 0.096	0.342LysCys: 0.342 ± 0.024	1.99LysAsp: 1.99 ± 0.066	3.661LysGlu: 3.661 ± 0.1	1.498LysPhe: 1.498 ± 0.053	3.634LysGly: 3.634 ± 0.073	1.089LysHis: 1.089 ± 0.047	3.558LysIle: 3.558 ± 0.081	3.762LysLys: 3.762 ± 0.092	4.874LysLeu: 4.874 ± 0.085	1.485LysMet: 1.485 ± 0.046	2.215LysAsn: 2.215 ± 0.075	2.682LysPro: 2.682 ± 0.069	1.851LysGln: 1.851 ± 0.056	3.138LysArg: 3.138 ± 0.072	3.403LysSer: 3.403 ± 0.074	3.026LysThr: 3.026 ± 0.064	3.666LysVal: 3.666 ± 0.092	0.405LysTrp: 0.405 ± 0.03	1.349LysTyr: 1.349 ± 0.049	0.0LysXaa: 0.0 ± 0.0
Leu	9.389LeuAla: 9.389 ± 0.146	1.143LeuCys: 1.143 ± 0.041	6.034LeuAsp: 6.034 ± 0.108	6.162LeuGlu: 6.162 ± 0.113	4.82LeuPhe: 4.82 ± 0.103	7.003LeuGly: 7.003 ± 0.102	2.13LeuHis: 2.13 ± 0.057	5.336LeuIle: 5.336 ± 0.099	5.472LeuLys: 5.472 ± 0.09	10.2LeuLeu: 10.2 ± 0.178	2.543LeuMet: 2.543 ± 0.062	3.305LeuAsn: 3.305 ± 0.087	4.779LeuPro: 4.779 ± 0.087	3.183LeuGln: 3.183 ± 0.082	5.839LeuArg: 5.839 ± 0.096	6.636LeuSer: 6.636 ± 0.124	4.869LeuThr: 4.869 ± 0.09	7.059LeuVal: 7.059 ± 0.098	0.967LeuTrp: 0.967 ± 0.047	2.624LeuTyr: 2.624 ± 0.065	0.0LeuXaa: 0.0 ± 0.0
Met	2.521MetAla: 2.521 ± 0.069	0.2MetCys: 0.2 ± 0.018	1.04MetAsp: 1.04 ± 0.035	1.495MetGlu: 1.495 ± 0.049	0.934MetPhe: 0.934 ± 0.043	1.664MetGly: 1.664 ± 0.051	0.584MetHis: 0.584 ± 0.033	1.75MetIle: 1.75 ± 0.056	1.955MetLys: 1.955 ± 0.054	3.08MetLeu: 3.08 ± 0.068	0.82MetMet: 0.82 ± 0.039	1.305MetAsn: 1.305 ± 0.052	1.574MetPro: 1.574 ± 0.046	1.172MetGln: 1.172 ± 0.045	1.553MetArg: 1.553 ± 0.048	1.784MetSer: 1.784 ± 0.059	1.623MetThr: 1.623 ± 0.049	1.955MetVal: 1.955 ± 0.06	0.171MetTrp: 0.171 ± 0.013	0.513MetTyr: 0.513 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.219AsnAla: 3.219 ± 0.082	0.375AsnCys: 0.375 ± 0.025	1.724AsnAsp: 1.724 ± 0.049	1.936AsnGlu: 1.936 ± 0.056	1.379AsnPhe: 1.379 ± 0.044	2.567AsnGly: 2.567 ± 0.062	0.76AsnHis: 0.76 ± 0.034	2.41AsnIle: 2.41 ± 0.066	1.444AsnLys: 1.444 ± 0.047	3.596AsnLeu: 3.596 ± 0.078	0.82AsnMet: 0.82 ± 0.042	1.159AsnAsn: 1.159 ± 0.051	2.31AsnPro: 2.31 ± 0.056	0.983AsnGln: 0.983 ± 0.043	2.275AsnArg: 2.275 ± 0.061	1.849AsnSer: 1.849 ± 0.065	1.572AsnThr: 1.572 ± 0.059	2.263AsnVal: 2.263 ± 0.057	0.401AsnTrp: 0.401 ± 0.028	1.078AsnTyr: 1.078 ± 0.04	0.002AsnXaa: 0.002 ± 0.002
Pro	4.262ProAla: 4.262 ± 0.09	0.454ProCys: 0.454 ± 0.024	2.975ProAsp: 2.975 ± 0.076	4.625ProGlu: 4.625 ± 0.094	2.096ProPhe: 2.096 ± 0.062	3.621ProGly: 3.621 ± 0.079	0.869ProHis: 0.869 ± 0.034	1.989ProIle: 1.989 ± 0.067	2.063ProLys: 2.063 ± 0.057	4.232ProLeu: 4.232 ± 0.079	1.081ProMet: 1.081 ± 0.039	1.347ProAsn: 1.347 ± 0.05	1.797ProPro: 1.797 ± 0.062	1.295ProGln: 1.295 ± 0.048	1.765ProArg: 1.765 ± 0.059	2.81ProSer: 2.81 ± 0.077	1.794ProThr: 1.794 ± 0.052	4.288ProVal: 4.288 ± 0.091	0.553ProTrp: 0.553 ± 0.031	1.279ProTyr: 1.279 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	3.059GlnAla: 3.059 ± 0.08	0.331GlnCys: 0.331 ± 0.023	1.154GlnAsp: 1.154 ± 0.041	2.098GlnGlu: 2.098 ± 0.054	1.205GlnPhe: 1.205 ± 0.043	1.951GlnGly: 1.951 ± 0.061	0.738GlnHis: 0.738 ± 0.034	1.94GlnIle: 1.94 ± 0.061	2.112GlnLys: 2.112 ± 0.064	3.227GlnLeu: 3.227 ± 0.071	0.891GlnMet: 0.891 ± 0.04	1.194GlnAsn: 1.194 ± 0.052	1.368GlnPro: 1.368 ± 0.046	1.406GlnGln: 1.406 ± 0.054	1.938GlnArg: 1.938 ± 0.06	1.881GlnSer: 1.881 ± 0.058	1.628GlnThr: 1.628 ± 0.055	2.028GlnVal: 2.028 ± 0.061	0.329GlnTrp: 0.329 ± 0.023	0.798GlnTyr: 0.798 ± 0.044	0.002GlnXaa: 0.002 ± 0.001
Arg	4.302ArgAla: 4.302 ± 0.077	0.714ArgCys: 0.714 ± 0.043	3.053ArgAsp: 3.053 ± 0.061	4.56ArgGlu: 4.56 ± 0.087	3.111ArgPhe: 3.111 ± 0.074	3.297ArgGly: 3.297 ± 0.079	1.509ArgHis: 1.509 ± 0.052	4.004ArgIle: 4.004 ± 0.072	3.935ArgLys: 3.935 ± 0.087	6.183ArgLeu: 6.183 ± 0.108	1.748ArgMet: 1.748 ± 0.052	2.405ArgAsn: 2.405 ± 0.07	2.468ArgPro: 2.468 ± 0.061	2.575ArgGln: 2.575 ± 0.068	3.886ArgArg: 3.886 ± 0.099	3.643ArgSer: 3.643 ± 0.08	2.625ArgThr: 2.625 ± 0.071	3.571ArgVal: 3.571 ± 0.085	0.697ArgTrp: 0.697 ± 0.033	2.221ArgTyr: 2.221 ± 0.064	0.0ArgXaa: 0.0 ± 0.0
Ser	5.675SerAla: 5.675 ± 0.089	0.754SerCys: 0.754 ± 0.032	3.048SerAsp: 3.048 ± 0.072	3.504SerGlu: 3.504 ± 0.076	2.826SerPhe: 2.826 ± 0.08	6.007SerGly: 6.007 ± 0.107	1.175SerHis: 1.175 ± 0.048	4.093SerIle: 4.093 ± 0.086	3.002SerLys: 3.002 ± 0.073	6.175SerLeu: 6.175 ± 0.113	2.008SerMet: 2.008 ± 0.052	2.087SerAsn: 2.087 ± 0.067	2.864SerPro: 2.864 ± 0.066	1.727SerGln: 1.727 ± 0.048	3.857SerArg: 3.857 ± 0.076	4.122SerSer: 4.122 ± 0.105	3.168SerThr: 3.168 ± 0.06	4.471SerVal: 4.471 ± 0.079	0.795SerTrp: 0.795 ± 0.032	1.677SerTyr: 1.677 ± 0.058	0.002SerXaa: 0.002 ± 0.002
Thr	4.76ThrAla: 4.76 ± 0.088	0.513ThrCys: 0.513 ± 0.03	2.411ThrAsp: 2.411 ± 0.062	2.815ThrGlu: 2.815 ± 0.066	2.095ThrPhe: 2.095 ± 0.056	5.026ThrGly: 5.026 ± 0.095	0.91ThrHis: 0.91 ± 0.035	3.667ThrIle: 3.667 ± 0.083	1.965ThrLys: 1.965 ± 0.07	5.236ThrLeu: 5.236 ± 0.086	1.341ThrMet: 1.341 ± 0.052	1.433ThrAsn: 1.433 ± 0.047	2.825ThrPro: 2.825 ± 0.074	1.184ThrGln: 1.184 ± 0.047	2.522ThrArg: 2.522 ± 0.069	3.092ThrSer: 3.092 ± 0.067	2.622ThrThr: 2.622 ± 0.07	4.091ThrVal: 4.091 ± 0.086	0.551ThrTrp: 0.551 ± 0.031	1.252ThrTyr: 1.252 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	6.381ValAla: 6.381 ± 0.104	0.879ValCys: 0.879 ± 0.041	3.639ValAsp: 3.639 ± 0.088	4.549ValGlu: 4.549 ± 0.092	3.132ValPhe: 3.132 ± 0.067	4.479ValGly: 4.479 ± 0.119	1.347ValHis: 1.347 ± 0.046	4.752ValIle: 4.752 ± 0.088	3.363ValLys: 3.363 ± 0.073	7.23ValLeu: 7.23 ± 0.115	2.065ValMet: 2.065 ± 0.057	2.44ValAsn: 2.44 ± 0.063	3.27ValPro: 3.27 ± 0.083	2.065ValGln: 2.065 ± 0.062	4.185ValArg: 4.185 ± 0.081	4.997ValSer: 4.997 ± 0.098	4.171ValThr: 4.171 ± 0.088	5.274ValVal: 5.274 ± 0.103	0.747ValTrp: 0.747 ± 0.04	1.707ValTyr: 1.707 ± 0.054	0.002ValXaa: 0.002 ± 0.002
Trp	0.804TrpAla: 0.804 ± 0.036	0.124TrpCys: 0.124 ± 0.015	0.462TrpAsp: 0.462 ± 0.032	0.583TrpGlu: 0.583 ± 0.03	0.621TrpPhe: 0.621 ± 0.03	0.61TrpGly: 0.61 ± 0.032	0.285TrpHis: 0.285 ± 0.018	0.678TrpIle: 0.678 ± 0.038	0.587TrpLys: 0.587 ± 0.031	1.419TrpLeu: 1.419 ± 0.049	0.367TrpMet: 0.367 ± 0.023	0.451TrpAsn: 0.451 ± 0.026	0.431TrpPro: 0.431 ± 0.026	0.548TrpGln: 0.548 ± 0.029	0.708TrpArg: 0.708 ± 0.042	0.678TrpSer: 0.678 ± 0.03	0.48TrpThr: 0.48 ± 0.028	0.572TrpVal: 0.572 ± 0.032	0.157TrpTrp: 0.157 ± 0.018	0.364TrpTyr: 0.364 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.302TyrAla: 2.302 ± 0.066	0.356TyrCys: 0.356 ± 0.024	1.685TyrAsp: 1.685 ± 0.05	1.645TyrGlu: 1.645 ± 0.056	1.325TyrPhe: 1.325 ± 0.055	2.378TyrGly: 2.378 ± 0.065	0.665TyrHis: 0.665 ± 0.034	1.528TyrIle: 1.528 ± 0.047	1.115TyrLys: 1.115 ± 0.046	2.989TyrLeu: 2.989 ± 0.087	0.594TyrMet: 0.594 ± 0.029	1.043TyrAsn: 1.043 ± 0.043	1.306TyrPro: 1.306 ± 0.037	0.895TyrGln: 0.895 ± 0.044	2.274TyrArg: 2.274 ± 0.067	1.724TyrSer: 1.724 ± 0.043	1.287TyrThr: 1.287 ± 0.043	1.686TyrVal: 1.686 ± 0.056	0.34TyrTrp: 0.34 ± 0.023	0.914TyrTyr: 0.914 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.002	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.003XaaArg: 0.003 ± 0.002	0.0XaaSer: 0.0 ± 0.0	0.002XaaThr: 0.002 ± 0.002	0.002XaaVal: 0.002 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2250 proteins (631563 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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