Human papillomavirus 134

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 7

Average proteome isoelectric point is 6.47

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|E7BQB3|E7BQB3_9PAPI Major capsid protein L1 OS=Human papillomavirus 134 OX=909333 GN=L1 PE=3 SV=1
MM1 pKa = 7.55SEE3 pKa = 4.18RR4 pKa = 11.84PRR6 pKa = 11.84KK7 pKa = 7.84RR8 pKa = 11.84TKK10 pKa = 10.15RR11 pKa = 11.84DD12 pKa = 3.18SVTNLYY18 pKa = 8.66NQCKK22 pKa = 9.99ISGSCPDD29 pKa = 3.53DD30 pKa = 3.52VKK32 pKa = 11.61NKK34 pKa = 9.99VEE36 pKa = 4.16EE37 pKa = 4.12TTLADD42 pKa = 3.73RR43 pKa = 11.84LLKK46 pKa = 10.35IFSSLVYY53 pKa = 10.23FGGLGIGTGKK63 pKa = 10.9GIGGSTGYY71 pKa = 10.26RR72 pKa = 11.84PLGGGSGRR80 pKa = 11.84VTAGGTVIRR89 pKa = 11.84PNVAVDD95 pKa = 3.43PLGPTDD101 pKa = 4.21IVPIDD106 pKa = 4.33SISPGTSSIVPLIEE120 pKa = 3.79VTPEE124 pKa = 3.72VVPEE128 pKa = 4.27LEE130 pKa = 4.19AGVINTGFDD139 pKa = 2.91ITTEE143 pKa = 3.8PDD145 pKa = 3.09IIEE148 pKa = 4.34ISSGSNTPAVSTIDD162 pKa = 3.25DD163 pKa = 3.61TAAVLEE169 pKa = 4.49VQPSTTTPRR178 pKa = 11.84RR179 pKa = 11.84VTTSKK184 pKa = 9.42FTNPTYY190 pKa = 8.44MTVVTEE196 pKa = 4.12STITPEE202 pKa = 4.07VSSTAGVFIDD212 pKa = 4.26GALGGDD218 pKa = 3.4VVGEE222 pKa = 4.27NIPLDD227 pKa = 3.89TFNEE231 pKa = 4.01PLEE234 pKa = 4.05FEE236 pKa = 4.3ILEE239 pKa = 4.13EE240 pKa = 4.03QQPKK244 pKa = 9.58TSTPIEE250 pKa = 4.2NVTRR254 pKa = 11.84ALGRR258 pKa = 11.84ARR260 pKa = 11.84EE261 pKa = 4.15LYY263 pKa = 9.51NRR265 pKa = 11.84RR266 pKa = 11.84VRR268 pKa = 11.84QVMTRR273 pKa = 11.84NPNFLTRR280 pKa = 11.84APQAVQFVFEE290 pKa = 4.94NPAFTNDD297 pKa = 2.87VTLTFEE303 pKa = 4.21QDD305 pKa = 3.08LNQIATAAPDD315 pKa = 3.96PDD317 pKa = 3.58FADD320 pKa = 4.07IIKK323 pKa = 10.57LEE325 pKa = 4.03RR326 pKa = 11.84PRR328 pKa = 11.84FSEE331 pKa = 4.06TAEE334 pKa = 3.98GTVRR338 pKa = 11.84LSRR341 pKa = 11.84LGTRR345 pKa = 11.84GTIRR349 pKa = 11.84TRR351 pKa = 11.84SGTQIGEE358 pKa = 4.16RR359 pKa = 11.84VHH361 pKa = 7.15FYY363 pKa = 11.36YY364 pKa = 10.73DD365 pKa = 3.25LSKK368 pKa = 10.72IEE370 pKa = 3.94NSEE373 pKa = 4.22AIEE376 pKa = 3.97LSVLGEE382 pKa = 4.04HH383 pKa = 6.78SGDD386 pKa = 3.12ATFINPLAEE395 pKa = 4.27STFVDD400 pKa = 4.2AEE402 pKa = 4.28NTNMPAIFPEE412 pKa = 4.23EE413 pKa = 4.03EE414 pKa = 4.14LVDD417 pKa = 5.0EE418 pKa = 4.24ITEE421 pKa = 4.33DD422 pKa = 3.82FSNSHH427 pKa = 5.45VVLINGSRR435 pKa = 11.84RR436 pKa = 11.84STMNVPTLPPGVALRR451 pKa = 11.84VYY453 pKa = 10.67VDD455 pKa = 4.62DD456 pKa = 4.2YY457 pKa = 12.01GEE459 pKa = 4.31GLFVSHH465 pKa = 6.39PQGRR469 pKa = 11.84EE470 pKa = 3.44LPAIITPGNAGRR482 pKa = 11.84PSILIDD488 pKa = 3.97DD489 pKa = 4.84FASNDD494 pKa = 3.68FVLHH498 pKa = 6.35PSLNRR503 pKa = 11.84KK504 pKa = 7.77KK505 pKa = 10.27RR506 pKa = 11.84KK507 pKa = 8.98RR508 pKa = 11.84KK509 pKa = 8.79QVHH512 pKa = 5.56FLL514 pKa = 3.45

Molecular weight: 55.88 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|E7BQA8|E7BQA8_9PAPI Protein E7 OS=Human papillomavirus 134 OX=909333 GN=E7 PE=3 SV=1
MM1 pKa = 7.4EE2 pKa = 5.23PVYY5 pKa = 10.45SIPALCRR12 pKa = 11.84LCRR15 pKa = 11.84VTIDD19 pKa = 4.11RR20 pKa = 11.84LHH22 pKa = 6.46LPCLFCHH29 pKa = 6.08NVLSLGDD36 pKa = 4.14LYY38 pKa = 11.87SFMFKK43 pKa = 10.63DD44 pKa = 3.64LNVVIRR50 pKa = 11.84GYY52 pKa = 11.04RR53 pKa = 11.84LFACCVNCLLISANYY68 pKa = 9.79EE69 pKa = 3.66MQQYY73 pKa = 7.28YY74 pKa = 9.66QCTANASTVQCLTRR88 pKa = 11.84KK89 pKa = 9.7SLLFLYY95 pKa = 9.14VRR97 pKa = 11.84CDD99 pKa = 3.11VCMKK103 pKa = 10.07PLSATEE109 pKa = 4.81KK110 pKa = 10.47FDD112 pKa = 4.85CLTKK116 pKa = 10.31NDD118 pKa = 3.73EE119 pKa = 4.09MHH121 pKa = 6.94LVRR124 pKa = 11.84SIWRR128 pKa = 11.84GTCRR132 pKa = 11.84LCRR135 pKa = 11.84KK136 pKa = 9.34KK137 pKa = 10.8

Molecular weight: 15.97 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2437

91

602

348.1

39.27

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.965 ± 0.258

2.216 ± 0.888

5.663 ± 0.371

6.689 ± 0.613

3.98 ± 0.377

5.827 ± 1.068

1.888 ± 0.205

4.924 ± 0.541

5.458 ± 0.922

9.315 ± 0.87

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.847 ± 0.415

5.006 ± 0.397

5.54 ± 0.968

3.939 ± 0.562

6.237 ± 0.804

8.289 ± 0.609

7.017 ± 1.209

6.648 ± 0.654

1.149 ± 0.312

3.406 ± 0.525
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski