Amino acid dipepetide frequency for Oscillochloris trichoides DG-6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.923AlaAla: 14.923 ± 0.161	1.018AlaCys: 1.018 ± 0.032	5.882AlaAsp: 5.882 ± 0.074	7.074AlaGlu: 7.074 ± 0.123	3.372AlaPhe: 3.372 ± 0.052	8.583AlaGly: 8.583 ± 0.095	2.512AlaHis: 2.512 ± 0.059	6.112AlaIle: 6.112 ± 0.083	2.258AlaLys: 2.258 ± 0.056	14.014AlaLeu: 14.014 ± 0.174	2.653AlaMet: 2.653 ± 0.057	3.063AlaAsn: 3.063 ± 0.06	5.609AlaPro: 5.609 ± 0.118	5.554AlaGln: 5.554 ± 0.091	7.265AlaArg: 7.265 ± 0.111	5.453AlaSer: 5.453 ± 0.074	6.71AlaThr: 6.71 ± 0.094	7.187AlaVal: 7.187 ± 0.094	1.71AlaTrp: 1.71 ± 0.051	2.951AlaTyr: 2.951 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.861CysAla: 0.861 ± 0.031	0.096CysCys: 0.096 ± 0.009	0.444CysAsp: 0.444 ± 0.021	0.391CysGlu: 0.391 ± 0.017	0.269CysPhe: 0.269 ± 0.017	0.831CysGly: 0.831 ± 0.032	0.257CysHis: 0.257 ± 0.022	0.384CysIle: 0.384 ± 0.017	0.145CysLys: 0.145 ± 0.012	0.721CysLeu: 0.721 ± 0.022	0.145CysMet: 0.145 ± 0.012	0.225CysAsn: 0.225 ± 0.013	0.472CysPro: 0.472 ± 0.022	0.325CysGln: 0.325 ± 0.016	0.53CysArg: 0.53 ± 0.021	0.5CysSer: 0.5 ± 0.023	0.467CysThr: 0.467 ± 0.022	0.493CysVal: 0.493 ± 0.021	0.119CysTrp: 0.119 ± 0.013	0.26CysTyr: 0.26 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	5.844AspAla: 5.844 ± 0.083	0.322AspCys: 0.322 ± 0.016	2.911AspAsp: 2.911 ± 0.066	3.024AspGlu: 3.024 ± 0.062	1.613AspPhe: 1.613 ± 0.04	4.345AspGly: 4.345 ± 0.102	1.151AspHis: 1.151 ± 0.035	2.294AspIle: 2.294 ± 0.048	0.857AspLys: 0.857 ± 0.028	7.585AspLeu: 7.585 ± 0.102	1.154AspMet: 1.154 ± 0.034	1.082AspAsn: 1.082 ± 0.056	3.564AspPro: 3.564 ± 0.062	2.284AspGln: 2.284 ± 0.043	3.198AspArg: 3.198 ± 0.046	2.17AspSer: 2.17 ± 0.044	2.627AspThr: 2.627 ± 0.059	3.663AspVal: 3.663 ± 0.065	0.785AspTrp: 0.785 ± 0.034	1.527AspTyr: 1.527 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	6.494GluAla: 6.494 ± 0.101	0.314GluCys: 0.314 ± 0.019	2.417GluAsp: 2.417 ± 0.05	3.282GluGlu: 3.282 ± 0.077	1.521GluPhe: 1.521 ± 0.037	3.545GluGly: 3.545 ± 0.062	1.439GluHis: 1.439 ± 0.04	3.166GluIle: 3.166 ± 0.058	1.257GluLys: 1.257 ± 0.039	6.029GluLeu: 6.029 ± 0.092	1.469GluMet: 1.469 ± 0.037	1.228GluAsn: 1.228 ± 0.035	2.732GluPro: 2.732 ± 0.087	3.355GluGln: 3.355 ± 0.066	5.409GluArg: 5.409 ± 0.08	2.441GluSer: 2.441 ± 0.045	2.675GluThr: 2.675 ± 0.05	4.32GluVal: 4.32 ± 0.064	0.716GluTrp: 0.716 ± 0.023	1.365GluTyr: 1.365 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.615PheAla: 3.615 ± 0.059	0.348PheCys: 0.348 ± 0.017	1.877PheAsp: 1.877 ± 0.048	1.658PheGlu: 1.658 ± 0.038	1.444PhePhe: 1.444 ± 0.041	3.012PheGly: 3.012 ± 0.057	0.656PheHis: 0.656 ± 0.023	1.625PheIle: 1.625 ± 0.042	0.656PheLys: 0.656 ± 0.025	3.097PheLeu: 3.097 ± 0.063	0.639PheMet: 0.639 ± 0.022	1.082PheAsn: 1.082 ± 0.031	1.527PhePro: 1.527 ± 0.037	1.184PheGln: 1.184 ± 0.034	1.891PheArg: 1.891 ± 0.043	2.091PheSer: 2.091 ± 0.054	1.983PheThr: 1.983 ± 0.05	2.484PheVal: 2.484 ± 0.046	0.599PheTrp: 0.599 ± 0.031	1.053PheTyr: 1.053 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	7.433GlyAla: 7.433 ± 0.104	0.699GlyCys: 0.699 ± 0.031	4.028GlyAsp: 4.028 ± 0.09	4.008GlyGlu: 4.008 ± 0.058	2.812GlyPhe: 2.812 ± 0.058	6.185GlyGly: 6.185 ± 0.111	1.789GlyHis: 1.789 ± 0.049	4.395GlyIle: 4.395 ± 0.069	2.217GlyLys: 2.217 ± 0.051	8.565GlyLeu: 8.565 ± 0.131	2.477GlyMet: 2.477 ± 0.045	2.186GlyAsn: 2.186 ± 0.086	3.154GlyPro: 3.154 ± 0.06	3.513GlyGln: 3.513 ± 0.066	5.239GlyArg: 5.239 ± 0.077	4.32GlySer: 4.32 ± 0.076	4.369GlyThr: 4.369 ± 0.106	6.236GlyVal: 6.236 ± 0.081	1.392GlyTrp: 1.392 ± 0.043	2.522GlyTyr: 2.522 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.579HisAla: 2.579 ± 0.052	0.205HisCys: 0.205 ± 0.012	1.273HisAsp: 1.273 ± 0.035	1.274HisGlu: 1.274 ± 0.039	0.726HisPhe: 0.726 ± 0.026	1.842HisGly: 1.842 ± 0.045	0.677HisHis: 0.677 ± 0.03	1.249HisIle: 1.249 ± 0.031	0.395HisLys: 0.395 ± 0.019	2.658HisLeu: 2.658 ± 0.057	0.423HisMet: 0.423 ± 0.019	0.636HisAsn: 0.636 ± 0.022	1.62HisPro: 1.62 ± 0.044	0.91HisGln: 0.91 ± 0.032	1.255HisArg: 1.255 ± 0.039	1.154HisSer: 1.154 ± 0.034	1.376HisThr: 1.376 ± 0.036	1.463HisVal: 1.463 ± 0.042	0.364HisTrp: 0.364 ± 0.017	0.737HisTyr: 0.737 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.634IleAla: 6.634 ± 0.093	0.54IleCys: 0.54 ± 0.022	3.095IleAsp: 3.095 ± 0.053	3.513IleGlu: 3.513 ± 0.064	2.259IlePhe: 2.259 ± 0.051	4.827IleGly: 4.827 ± 0.069	1.132IleHis: 1.132 ± 0.034	3.054IleIle: 3.054 ± 0.074	1.283IleLys: 1.283 ± 0.035	5.137IleLeu: 5.137 ± 0.074	1.095IleMet: 1.095 ± 0.032	1.863IleAsn: 1.863 ± 0.044	2.973IlePro: 2.973 ± 0.05	1.974IleGln: 1.974 ± 0.042	3.225IleArg: 3.225 ± 0.052	3.597IleSer: 3.597 ± 0.062	3.532IleThr: 3.532 ± 0.07	3.771IleVal: 3.771 ± 0.055	0.905IleTrp: 0.905 ± 0.033	1.731IleTyr: 1.731 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	2.145LysAla: 2.145 ± 0.056	0.095LysCys: 0.095 ± 0.009	1.008LysAsp: 1.008 ± 0.034	1.122LysGlu: 1.122 ± 0.035	0.575LysPhe: 0.575 ± 0.023	1.507LysGly: 1.507 ± 0.041	0.46LysHis: 0.46 ± 0.023	1.368LysIle: 1.368 ± 0.039	0.652LysLys: 0.652 ± 0.025	2.284LysLeu: 2.284 ± 0.052	0.531LysMet: 0.531 ± 0.022	0.581LysAsn: 0.581 ± 0.025	1.322LysPro: 1.322 ± 0.039	0.948LysGln: 0.948 ± 0.032	1.553LysArg: 1.553 ± 0.042	1.03LysSer: 1.03 ± 0.03	1.162LysThr: 1.162 ± 0.033	1.629LysVal: 1.629 ± 0.036	0.186LysTrp: 0.186 ± 0.014	0.521LysTyr: 0.521 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	14.217LeuAla: 14.217 ± 0.179	0.919LeuCys: 0.919 ± 0.027	6.148LeuAsp: 6.148 ± 0.085	5.793LeuGlu: 5.793 ± 0.081	3.562LeuPhe: 3.562 ± 0.065	8.832LeuGly: 8.832 ± 0.128	2.738LeuHis: 2.738 ± 0.056	6.623LeuIle: 6.623 ± 0.105	2.334LeuLys: 2.334 ± 0.052	13.534LeuLeu: 13.534 ± 0.234	2.168LeuMet: 2.168 ± 0.045	3.268LeuAsn: 3.268 ± 0.068	6.718LeuPro: 6.718 ± 0.091	3.801LeuGln: 3.801 ± 0.061	9.236LeuArg: 9.236 ± 0.145	6.296LeuSer: 6.296 ± 0.084	5.883LeuThr: 5.883 ± 0.077	8.373LeuVal: 8.373 ± 0.09	1.393LeuTrp: 1.393 ± 0.053	2.581LeuTyr: 2.581 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.674MetAla: 2.674 ± 0.057	0.133MetCys: 0.133 ± 0.01	0.918MetAsp: 0.918 ± 0.028	0.987MetGlu: 0.987 ± 0.033	0.538MetPhe: 0.538 ± 0.02	1.686MetGly: 1.686 ± 0.042	0.476MetHis: 0.476 ± 0.019	1.505MetIle: 1.505 ± 0.038	0.472MetLys: 0.472 ± 0.019	3.016MetLeu: 3.016 ± 0.055	0.521MetMet: 0.521 ± 0.021	0.637MetAsn: 0.637 ± 0.021	1.459MetPro: 1.459 ± 0.035	1.041MetGln: 1.041 ± 0.035	1.814MetArg: 1.814 ± 0.039	1.392MetSer: 1.392 ± 0.034	1.278MetThr: 1.278 ± 0.03	1.728MetVal: 1.728 ± 0.04	0.207MetTrp: 0.207 ± 0.014	0.362MetTyr: 0.362 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.857AsnAla: 2.857 ± 0.055	0.202AsnCys: 0.202 ± 0.013	1.535AsnAsp: 1.535 ± 0.06	1.399AsnGlu: 1.399 ± 0.041	0.918AsnPhe: 0.918 ± 0.031	2.272AsnGly: 2.272 ± 0.091	0.568AsnHis: 0.568 ± 0.022	1.376AsnIle: 1.376 ± 0.038	0.516AsnLys: 0.516 ± 0.02	3.425AsnLeu: 3.425 ± 0.063	0.542AsnMet: 0.542 ± 0.022	0.954AsnAsn: 0.954 ± 0.051	2.393AsnPro: 2.393 ± 0.053	1.434AsnGln: 1.434 ± 0.042	1.834AsnArg: 1.834 ± 0.041	1.277AsnSer: 1.277 ± 0.043	1.662AsnThr: 1.662 ± 0.048	1.792AsnVal: 1.792 ± 0.049	0.391AsnTrp: 0.391 ± 0.021	0.886AsnTyr: 0.886 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	6.353ProAla: 6.353 ± 0.105	0.324ProCys: 0.324 ± 0.016	3.781ProAsp: 3.781 ± 0.061	3.525ProGlu: 3.525 ± 0.07	1.899ProPhe: 1.899 ± 0.047	4.112ProGly: 4.112 ± 0.073	1.351ProHis: 1.351 ± 0.038	3.007ProIle: 3.007 ± 0.053	1.103ProLys: 1.103 ± 0.036	5.997ProLeu: 5.997 ± 0.09	1.105ProMet: 1.105 ± 0.029	1.854ProAsn: 1.854 ± 0.038	3.899ProPro: 3.899 ± 0.09	2.512ProGln: 2.512 ± 0.046	3.103ProArg: 3.103 ± 0.061	3.194ProSer: 3.194 ± 0.063	4.04ProThr: 4.04 ± 0.115	3.983ProVal: 3.983 ± 0.073	0.786ProTrp: 0.786 ± 0.03	1.364ProTyr: 1.364 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	5.226GlnAla: 5.226 ± 0.088	0.245GlnCys: 0.245 ± 0.015	1.491GlnAsp: 1.491 ± 0.039	2.016GlnGlu: 2.016 ± 0.048	1.118GlnPhe: 1.118 ± 0.03	2.89GlnGly: 2.89 ± 0.066	1.192GlnHis: 1.192 ± 0.033	3.422GlnIle: 3.422 ± 0.052	0.822GlnLys: 0.822 ± 0.027	4.496GlnLeu: 4.496 ± 0.063	1.12GlnMet: 1.12 ± 0.032	0.991GlnAsn: 0.991 ± 0.033	2.788GlnPro: 2.788 ± 0.049	2.439GlnGln: 2.439 ± 0.066	4.176GlnArg: 4.176 ± 0.074	2.279GlnSer: 2.279 ± 0.048	2.215GlnThr: 2.215 ± 0.047	3.652GlnVal: 3.652 ± 0.055	0.454GlnTrp: 0.454 ± 0.023	0.861GlnTyr: 0.861 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	7.009ArgAla: 7.009 ± 0.098	0.558ArgCys: 0.558 ± 0.022	3.663ArgAsp: 3.663 ± 0.057	4.284ArgGlu: 4.284 ± 0.08	2.464ArgPhe: 2.464 ± 0.041	4.654ArgGly: 4.654 ± 0.064	1.687ArgHis: 1.687 ± 0.047	4.101ArgIle: 4.101 ± 0.074	1.505ArgLys: 1.505 ± 0.041	8.096ArgLeu: 8.096 ± 0.117	1.864ArgMet: 1.864 ± 0.041	1.991ArgAsn: 1.991 ± 0.043	3.617ArgPro: 3.617 ± 0.063	3.202ArgGln: 3.202 ± 0.056	5.568ArgArg: 5.568 ± 0.101	4.143ArgSer: 4.143 ± 0.067	3.637ArgThr: 3.637 ± 0.06	4.877ArgVal: 4.877 ± 0.061	1.182ArgTrp: 1.182 ± 0.035	2.374ArgTyr: 2.374 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	5.867SerAla: 5.867 ± 0.075	0.376SerCys: 0.376 ± 0.018	2.998SerAsp: 2.998 ± 0.063	2.877SerGlu: 2.877 ± 0.053	2.001SerPhe: 2.001 ± 0.043	4.917SerGly: 4.917 ± 0.091	1.223SerHis: 1.223 ± 0.034	2.921SerIle: 2.921 ± 0.05	1.008SerLys: 1.008 ± 0.027	6.103SerLeu: 6.103 ± 0.085	1.219SerMet: 1.219 ± 0.035	1.628SerAsn: 1.628 ± 0.049	3.131SerPro: 3.131 ± 0.058	2.199SerGln: 2.199 ± 0.042	3.282SerArg: 3.282 ± 0.058	3.37SerSer: 3.37 ± 0.072	2.892SerThr: 2.892 ± 0.066	3.533SerVal: 3.533 ± 0.059	0.768SerTrp: 0.768 ± 0.025	1.576SerTyr: 1.576 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.502ThrAla: 5.502 ± 0.09	0.552ThrCys: 0.552 ± 0.026	2.617ThrAsp: 2.617 ± 0.074	2.587ThrGlu: 2.587 ± 0.052	2.1ThrPhe: 2.1 ± 0.048	4.175ThrGly: 4.175 ± 0.087	1.174ThrHis: 1.174 ± 0.03	3.425ThrIle: 3.425 ± 0.063	1.067ThrLys: 1.067 ± 0.031	6.958ThrLeu: 6.958 ± 0.078	1.221ThrMet: 1.221 ± 0.032	1.698ThrAsn: 1.698 ± 0.066	4.511ThrPro: 4.511 ± 0.099	2.265ThrGln: 2.265 ± 0.05	3.214ThrArg: 3.214 ± 0.06	3.343ThrSer: 3.343 ± 0.077	3.654ThrThr: 3.654 ± 0.121	3.769ThrVal: 3.769 ± 0.087	0.91ThrTrp: 0.91 ± 0.036	1.664ThrTyr: 1.664 ± 0.061	0.0ThrXaa: 0.0 ± 0.0
Val	9.261ValAla: 9.261 ± 0.118	0.632ValCys: 0.632 ± 0.024	3.617ValAsp: 3.617 ± 0.067	4.21ValGlu: 4.21 ± 0.064	1.977ValPhe: 1.977 ± 0.041	5.948ValGly: 5.948 ± 0.087	1.282ValHis: 1.282 ± 0.04	4.145ValIle: 4.145 ± 0.058	1.347ValLys: 1.347 ± 0.042	7.719ValLeu: 7.719 ± 0.104	1.584ValMet: 1.584 ± 0.039	1.846ValAsn: 1.846 ± 0.043	3.658ValPro: 3.658 ± 0.057	2.81ValGln: 2.81 ± 0.051	5.3ValArg: 5.3 ± 0.063	3.733ValSer: 3.733 ± 0.062	3.911ValThr: 3.911 ± 0.095	6.271ValVal: 6.271 ± 0.092	0.934ValTrp: 0.934 ± 0.035	1.777ValTyr: 1.777 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.416TrpAla: 1.416 ± 0.044	0.121TrpCys: 0.121 ± 0.009	0.644TrpAsp: 0.644 ± 0.031	0.771TrpGlu: 0.771 ± 0.027	0.458TrpPhe: 0.458 ± 0.02	1.18TrpGly: 1.18 ± 0.042	0.353TrpHis: 0.353 ± 0.017	0.698TrpIle: 0.698 ± 0.024	0.29TrpLys: 0.29 ± 0.015	1.842TrpLeu: 1.842 ± 0.057	0.417TrpMet: 0.417 ± 0.019	0.584TrpAsn: 0.584 ± 0.029	0.723TrpPro: 0.723 ± 0.03	0.835TrpGln: 0.835 ± 0.03	1.204TrpArg: 1.204 ± 0.036	0.747TrpSer: 0.747 ± 0.029	0.534TrpThr: 0.534 ± 0.023	0.976TrpVal: 0.976 ± 0.026	0.298TrpTrp: 0.298 ± 0.02	0.419TrpTyr: 0.419 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.992TyrAla: 2.992 ± 0.055	0.235TyrCys: 0.235 ± 0.014	1.653TyrAsp: 1.653 ± 0.064	1.378TyrGlu: 1.378 ± 0.04	0.898TyrPhe: 0.898 ± 0.03	2.194TyrGly: 2.194 ± 0.051	0.699TyrHis: 0.699 ± 0.023	1.27TyrIle: 1.27 ± 0.03	0.495TyrLys: 0.495 ± 0.024	3.144TyrLeu: 3.144 ± 0.056	0.497TyrMet: 0.497 ± 0.023	0.836TyrAsn: 0.836 ± 0.027	1.42TyrPro: 1.42 ± 0.032	1.307TyrGln: 1.307 ± 0.033	2.18TyrArg: 2.18 ± 0.037	1.361TyrSer: 1.361 ± 0.035	1.799TyrThr: 1.799 ± 0.052	1.762TyrVal: 1.762 ± 0.048	0.41TyrTrp: 0.41 ± 0.019	0.853TyrTyr: 0.853 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3230 proteins (1244527 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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