Amino acid dipepetide frequency for Ahrensia marina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.273AlaAla: 12.273 ± 0.161	0.912AlaCys: 0.912 ± 0.033	6.073AlaAsp: 6.073 ± 0.088	6.653AlaGlu: 6.653 ± 0.103	4.274AlaPhe: 4.274 ± 0.074	8.816AlaGly: 8.816 ± 0.118	2.039AlaHis: 2.039 ± 0.05	6.948AlaIle: 6.948 ± 0.091	5.284AlaLys: 5.284 ± 0.094	11.4AlaLeu: 11.4 ± 0.128	3.419AlaMet: 3.419 ± 0.064	3.385AlaAsn: 3.385 ± 0.061	4.075AlaPro: 4.075 ± 0.06	3.722AlaGln: 3.722 ± 0.065	5.733AlaArg: 5.733 ± 0.08	6.203AlaSer: 6.203 ± 0.08	5.125AlaThr: 5.125 ± 0.083	7.397AlaVal: 7.397 ± 0.101	1.153AlaTrp: 1.153 ± 0.039	2.514AlaTyr: 2.514 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.015CysAla: 1.015 ± 0.032	0.104CysCys: 0.104 ± 0.011	0.583CysAsp: 0.583 ± 0.022	0.527CysGlu: 0.527 ± 0.022	0.366CysPhe: 0.366 ± 0.021	0.933CysGly: 0.933 ± 0.029	0.256CysHis: 0.256 ± 0.015	0.504CysIle: 0.504 ± 0.021	0.311CysLys: 0.311 ± 0.018	0.769CysLeu: 0.769 ± 0.028	0.209CysMet: 0.209 ± 0.017	0.25CysAsn: 0.25 ± 0.018	0.435CysPro: 0.435 ± 0.022	0.257CysGln: 0.257 ± 0.018	0.449CysArg: 0.449 ± 0.026	0.513CysSer: 0.513 ± 0.029	0.453CysThr: 0.453 ± 0.023	0.605CysVal: 0.605 ± 0.028	0.112CysTrp: 0.112 ± 0.01	0.212CysTyr: 0.212 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.306AspAla: 6.306 ± 0.084	0.539AspCys: 0.539 ± 0.027	3.731AspAsp: 3.731 ± 0.085	4.241AspGlu: 4.241 ± 0.078	2.347AspPhe: 2.347 ± 0.046	4.954AspGly: 4.954 ± 0.078	1.294AspHis: 1.294 ± 0.039	4.047AspIle: 4.047 ± 0.075	2.646AspLys: 2.646 ± 0.048	5.522AspLeu: 5.522 ± 0.081	1.785AspMet: 1.785 ± 0.05	2.109AspAsn: 2.109 ± 0.046	2.727AspPro: 2.727 ± 0.055	1.922AspGln: 1.922 ± 0.041	3.242AspArg: 3.242 ± 0.058	2.498AspSer: 2.498 ± 0.048	2.766AspThr: 2.766 ± 0.059	4.269AspVal: 4.269 ± 0.072	0.886AspTrp: 0.886 ± 0.033	1.687AspTyr: 1.687 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	7.003GluAla: 7.003 ± 0.111	0.393GluCys: 0.393 ± 0.021	3.299GluAsp: 3.299 ± 0.053	3.91GluGlu: 3.91 ± 0.095	2.224GluPhe: 2.224 ± 0.049	4.319GluGly: 4.319 ± 0.07	1.242GluHis: 1.242 ± 0.032	4.205GluIle: 4.205 ± 0.074	3.67GluLys: 3.67 ± 0.074	5.597GluLeu: 5.597 ± 0.089	1.876GluMet: 1.876 ± 0.048	2.738GluAsn: 2.738 ± 0.06	2.458GluPro: 2.458 ± 0.054	2.401GluGln: 2.401 ± 0.059	4.18GluArg: 4.18 ± 0.075	2.67GluSer: 2.67 ± 0.056	3.885GluThr: 3.885 ± 0.058	3.658GluVal: 3.658 ± 0.059	0.721GluTrp: 0.721 ± 0.031	1.28GluTyr: 1.28 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	4.466PheAla: 4.466 ± 0.082	0.47PheCys: 0.47 ± 0.02	3.006PheAsp: 3.006 ± 0.057	2.7PheGlu: 2.7 ± 0.062	1.774PhePhe: 1.774 ± 0.046	3.814PheGly: 3.814 ± 0.066	0.734PheHis: 0.734 ± 0.026	2.361PheIle: 2.361 ± 0.056	1.673PheLys: 1.673 ± 0.039	3.687PheLeu: 3.687 ± 0.079	1.079PheMet: 1.079 ± 0.034	1.438PheAsn: 1.438 ± 0.036	1.543PhePro: 1.543 ± 0.041	1.186PheGln: 1.186 ± 0.035	1.83PheArg: 1.83 ± 0.046	2.716PheSer: 2.716 ± 0.052	2.223PheThr: 2.223 ± 0.052	2.92PheVal: 2.92 ± 0.062	0.59PheTrp: 0.59 ± 0.028	1.077PheTyr: 1.077 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	7.855GlyAla: 7.855 ± 0.108	0.835GlyCys: 0.835 ± 0.031	4.305GlyAsp: 4.305 ± 0.076	4.714GlyGlu: 4.714 ± 0.081	3.817GlyPhe: 3.817 ± 0.067	6.586GlyGly: 6.586 ± 0.102	1.76GlyHis: 1.76 ± 0.045	5.211GlyIle: 5.211 ± 0.076	4.111GlyLys: 4.111 ± 0.069	7.831GlyLeu: 7.831 ± 0.098	2.306GlyMet: 2.306 ± 0.045	2.682GlyAsn: 2.682 ± 0.052	2.749GlyPro: 2.749 ± 0.043	2.711GlyGln: 2.711 ± 0.056	4.297GlyArg: 4.297 ± 0.064	4.536GlySer: 4.536 ± 0.071	4.342GlyThr: 4.342 ± 0.067	5.712GlyVal: 5.712 ± 0.087	1.122GlyTrp: 1.122 ± 0.033	2.336GlyTyr: 2.336 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.867HisAla: 1.867 ± 0.051	0.261HisCys: 0.261 ± 0.019	1.284HisAsp: 1.284 ± 0.048	1.173HisGlu: 1.173 ± 0.035	0.931HisPhe: 0.931 ± 0.029	1.697HisGly: 1.697 ± 0.044	0.542HisHis: 0.542 ± 0.029	1.235HisIle: 1.235 ± 0.039	0.779HisLys: 0.779 ± 0.025	1.923HisLeu: 1.923 ± 0.047	0.576HisMet: 0.576 ± 0.026	0.661HisAsn: 0.661 ± 0.027	1.088HisPro: 1.088 ± 0.035	0.605HisGln: 0.605 ± 0.027	1.048HisArg: 1.048 ± 0.036	1.072HisSer: 1.072 ± 0.036	0.867HisThr: 0.867 ± 0.03	1.337HisVal: 1.337 ± 0.037	0.263HisTrp: 0.263 ± 0.015	0.588HisTyr: 0.588 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	8.03IleAla: 8.03 ± 0.1	0.734IleCys: 0.734 ± 0.03	4.322IleAsp: 4.322 ± 0.069	4.302IleGlu: 4.302 ± 0.075	2.463IlePhe: 2.463 ± 0.058	5.545IleGly: 5.545 ± 0.084	1.048IleHis: 1.048 ± 0.034	3.987IleIle: 3.987 ± 0.076	2.714IleLys: 2.714 ± 0.053	5.474IleLeu: 5.474 ± 0.094	1.494IleMet: 1.494 ± 0.041	2.308IleAsn: 2.308 ± 0.053	2.439IlePro: 2.439 ± 0.054	1.489IleGln: 1.489 ± 0.04	2.98IleArg: 2.98 ± 0.056	4.056IleSer: 4.056 ± 0.062	3.338IleThr: 3.338 ± 0.058	4.772IleVal: 4.772 ± 0.082	0.72IleTrp: 0.72 ± 0.028	1.546IleTyr: 1.546 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.182LysAla: 5.182 ± 0.079	0.275LysCys: 0.275 ± 0.016	2.563LysAsp: 2.563 ± 0.052	2.569LysGlu: 2.569 ± 0.065	1.506LysPhe: 1.506 ± 0.04	3.17LysGly: 3.17 ± 0.059	0.954LysHis: 0.954 ± 0.028	3.007LysIle: 3.007 ± 0.063	2.531LysLys: 2.531 ± 0.063	4.38LysLeu: 4.38 ± 0.064	1.395LysMet: 1.395 ± 0.039	1.855LysAsn: 1.855 ± 0.047	2.528LysPro: 2.528 ± 0.052	1.683LysGln: 1.683 ± 0.045	3.122LysArg: 3.122 ± 0.059	3.153LysSer: 3.153 ± 0.059	2.935LysThr: 2.935 ± 0.054	2.941LysVal: 2.941 ± 0.051	0.555LysTrp: 0.555 ± 0.023	0.996LysTyr: 0.996 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	10.271LeuAla: 10.271 ± 0.12	0.922LeuCys: 0.922 ± 0.027	5.629LeuAsp: 5.629 ± 0.077	5.703LeuGlu: 5.703 ± 0.091	3.791LeuPhe: 3.791 ± 0.067	7.586LeuGly: 7.586 ± 0.105	1.65LeuHis: 1.65 ± 0.039	5.889LeuIle: 5.889 ± 0.104	4.664LeuLys: 4.664 ± 0.072	8.492LeuLeu: 8.492 ± 0.116	2.466LeuMet: 2.466 ± 0.056	3.445LeuAsn: 3.445 ± 0.066	4.724LeuPro: 4.724 ± 0.08	2.681LeuGln: 2.681 ± 0.048	5.154LeuArg: 5.154 ± 0.076	6.756LeuSer: 6.756 ± 0.101	5.359LeuThr: 5.359 ± 0.079	6.551LeuVal: 6.551 ± 0.096	1.016LeuTrp: 1.016 ± 0.03	2.142LeuTyr: 2.142 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	3.136MetAla: 3.136 ± 0.056	0.209MetCys: 0.209 ± 0.015	1.43MetAsp: 1.43 ± 0.035	1.46MetGlu: 1.46 ± 0.036	0.994MetPhe: 0.994 ± 0.034	2.057MetGly: 2.057 ± 0.055	0.461MetHis: 0.461 ± 0.024	1.792MetIle: 1.792 ± 0.042	1.394MetLys: 1.394 ± 0.038	2.681MetLeu: 2.681 ± 0.053	0.852MetMet: 0.852 ± 0.029	1.127MetAsn: 1.127 ± 0.035	1.52MetPro: 1.52 ± 0.044	0.958MetGln: 0.958 ± 0.031	1.812MetArg: 1.812 ± 0.045	2.032MetSer: 2.032 ± 0.046	1.896MetThr: 1.896 ± 0.048	1.908MetVal: 1.908 ± 0.05	0.213MetTrp: 0.213 ± 0.018	0.394MetTyr: 0.394 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	4.101AsnAla: 4.101 ± 0.069	0.349AsnCys: 0.349 ± 0.019	2.088AsnAsp: 2.088 ± 0.051	1.981AsnGlu: 1.981 ± 0.047	1.389AsnPhe: 1.389 ± 0.038	3.023AsnGly: 3.023 ± 0.06	0.719AsnHis: 0.719 ± 0.028	2.396AsnIle: 2.396 ± 0.058	1.509AsnLys: 1.509 ± 0.039	3.026AsnLeu: 3.026 ± 0.057	0.988AsnMet: 0.988 ± 0.031	1.274AsnAsn: 1.274 ± 0.037	2.034AsnPro: 2.034 ± 0.048	1.137AsnGln: 1.137 ± 0.034	1.995AsnArg: 1.995 ± 0.046	1.814AsnSer: 1.814 ± 0.044	1.731AsnThr: 1.731 ± 0.043	2.544AsnVal: 2.544 ± 0.051	0.532AsnTrp: 0.532 ± 0.024	1.015AsnTyr: 1.015 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	4.326ProAla: 4.326 ± 0.065	0.278ProCys: 0.278 ± 0.018	3.247ProAsp: 3.247 ± 0.061	3.447ProGlu: 3.447 ± 0.06	2.009ProPhe: 2.009 ± 0.049	2.992ProGly: 2.992 ± 0.051	0.937ProHis: 0.937 ± 0.029	2.469ProIle: 2.469 ± 0.051	1.998ProLys: 1.998 ± 0.045	3.896ProLeu: 3.896 ± 0.072	1.16ProMet: 1.16 ± 0.035	1.624ProAsn: 1.624 ± 0.044	1.555ProPro: 1.555 ± 0.047	1.598ProGln: 1.598 ± 0.038	1.942ProArg: 1.942 ± 0.043	2.681ProSer: 2.681 ± 0.049	2.144ProThr: 2.144 ± 0.047	3.747ProVal: 3.747 ± 0.059	0.533ProTrp: 0.533 ± 0.024	1.231ProTyr: 1.231 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.52GlnAla: 3.52 ± 0.063	0.216GlnCys: 0.216 ± 0.015	1.584GlnAsp: 1.584 ± 0.038	1.7GlnGlu: 1.7 ± 0.04	1.347GlnPhe: 1.347 ± 0.039	2.049GlnGly: 2.049 ± 0.048	0.6GlnHis: 0.6 ± 0.026	2.33GlnIle: 2.33 ± 0.051	1.732GlnLys: 1.732 ± 0.037	3.015GlnLeu: 3.015 ± 0.057	1.167GlnMet: 1.167 ± 0.038	1.345GlnAsn: 1.345 ± 0.038	1.416GlnPro: 1.416 ± 0.043	1.202GlnGln: 1.202 ± 0.048	2.081GlnArg: 2.081 ± 0.059	2.285GlnSer: 2.285 ± 0.054	1.896GlnThr: 1.896 ± 0.043	2.103GlnVal: 2.103 ± 0.048	0.385GlnTrp: 0.385 ± 0.021	0.704GlnTyr: 0.704 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	5.459ArgAla: 5.459 ± 0.081	0.394ArgCys: 0.394 ± 0.02	3.245ArgAsp: 3.245 ± 0.067	3.486ArgGlu: 3.486 ± 0.063	2.493ArgPhe: 2.493 ± 0.047	3.663ArgGly: 3.663 ± 0.07	1.229ArgHis: 1.229 ± 0.032	3.611ArgIle: 3.611 ± 0.058	2.637ArgLys: 2.637 ± 0.057	5.564ArgLeu: 5.564 ± 0.084	1.606ArgMet: 1.606 ± 0.038	2.075ArgAsn: 2.075 ± 0.046	2.232ArgPro: 2.232 ± 0.05	2.054ArgGln: 2.054 ± 0.048	3.427ArgArg: 3.427 ± 0.078	3.327ArgSer: 3.327 ± 0.064	2.777ArgThr: 2.777 ± 0.054	3.632ArgVal: 3.632 ± 0.069	0.644ArgTrp: 0.644 ± 0.025	1.437ArgTyr: 1.437 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.277SerAla: 6.277 ± 0.088	0.465SerCys: 0.465 ± 0.024	3.659SerAsp: 3.659 ± 0.065	3.624SerGlu: 3.624 ± 0.065	2.633SerPhe: 2.633 ± 0.055	5.751SerGly: 5.751 ± 0.068	1.209SerHis: 1.209 ± 0.038	3.667SerIle: 3.667 ± 0.068	2.858SerLys: 2.858 ± 0.051	5.61SerLeu: 5.61 ± 0.079	1.626SerMet: 1.626 ± 0.041	2.042SerAsn: 2.042 ± 0.048	2.445SerPro: 2.445 ± 0.052	1.994SerGln: 1.994 ± 0.048	3.033SerArg: 3.033 ± 0.065	3.534SerSer: 3.534 ± 0.067	3.052SerThr: 3.052 ± 0.049	4.32SerVal: 4.32 ± 0.074	0.709SerTrp: 0.709 ± 0.029	1.433SerTyr: 1.433 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.543ThrAla: 5.543 ± 0.08	0.462ThrCys: 0.462 ± 0.023	3.087ThrAsp: 3.087 ± 0.058	2.815ThrGlu: 2.815 ± 0.056	2.174ThrPhe: 2.174 ± 0.05	4.896ThrGly: 4.896 ± 0.069	1.094ThrHis: 1.094 ± 0.035	3.614ThrIle: 3.614 ± 0.067	2.281ThrLys: 2.281 ± 0.052	5.48ThrLeu: 5.48 ± 0.084	1.451ThrMet: 1.451 ± 0.042	1.797ThrAsn: 1.797 ± 0.044	2.853ThrPro: 2.853 ± 0.06	1.615ThrGln: 1.615 ± 0.039	2.669ThrArg: 2.669 ± 0.059	3.196ThrSer: 3.196 ± 0.061	2.765ThrThr: 2.765 ± 0.055	4.084ThrVal: 4.084 ± 0.071	0.603ThrTrp: 0.603 ± 0.029	1.297ThrTyr: 1.297 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	7.275ValAla: 7.275 ± 0.101	0.636ValCys: 0.636 ± 0.025	4.174ValAsp: 4.174 ± 0.065	4.594ValGlu: 4.594 ± 0.069	3.1ValPhe: 3.1 ± 0.057	5.134ValGly: 5.134 ± 0.087	1.239ValHis: 1.239 ± 0.04	4.464ValIle: 4.464 ± 0.075	2.995ValLys: 2.995 ± 0.06	6.774ValLeu: 6.774 ± 0.088	1.907ValMet: 1.907 ± 0.042	2.256ValAsn: 2.256 ± 0.047	3.273ValPro: 3.273 ± 0.054	2.05ValGln: 2.05 ± 0.05	3.711ValArg: 3.711 ± 0.067	4.688ValSer: 4.688 ± 0.076	4.274ValThr: 4.274 ± 0.07	5.055ValVal: 5.055 ± 0.074	0.787ValTrp: 0.787 ± 0.025	1.535ValTyr: 1.535 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.045TrpAla: 1.045 ± 0.037	0.119TrpCys: 0.119 ± 0.011	0.611TrpAsp: 0.611 ± 0.026	0.561TrpGlu: 0.561 ± 0.023	0.585TrpPhe: 0.585 ± 0.025	0.73TrpGly: 0.73 ± 0.025	0.296TrpHis: 0.296 ± 0.019	0.712TrpIle: 0.712 ± 0.028	0.527TrpLys: 0.527 ± 0.024	1.417TrpLeu: 1.417 ± 0.039	0.363TrpMet: 0.363 ± 0.021	0.448TrpAsn: 0.448 ± 0.021	0.609TrpPro: 0.609 ± 0.026	0.6TrpGln: 0.6 ± 0.024	0.839TrpArg: 0.839 ± 0.027	0.78TrpSer: 0.78 ± 0.027	0.692TrpThr: 0.692 ± 0.031	0.693TrpVal: 0.693 ± 0.031	0.215TrpTrp: 0.215 ± 0.014	0.285TrpTyr: 0.285 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.448TyrAla: 2.448 ± 0.054	0.289TyrCys: 0.289 ± 0.019	1.597TyrAsp: 1.597 ± 0.043	1.568TyrGlu: 1.568 ± 0.04	1.068TyrPhe: 1.068 ± 0.035	2.103TyrGly: 2.103 ± 0.053	0.495TyrHis: 0.495 ± 0.021	1.312TyrIle: 1.312 ± 0.039	0.986TyrLys: 0.986 ± 0.035	2.353TyrLeu: 2.353 ± 0.044	0.601TyrMet: 0.601 ± 0.025	0.788TyrAsn: 0.788 ± 0.037	1.109TyrPro: 1.109 ± 0.037	0.811TyrGln: 0.811 ± 0.03	1.45TyrArg: 1.45 ± 0.04	1.431TyrSer: 1.431 ± 0.036	1.255TyrThr: 1.255 ± 0.037	1.675TyrVal: 1.675 ± 0.043	0.366TyrTrp: 0.366 ± 0.021	0.714TyrTyr: 0.714 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3161 proteins (971630 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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