Amino acid dipepetide frequency for Phytohabitans suffuscus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.526AlaAla: 23.526 ± 0.161	1.092AlaCys: 1.092 ± 0.02	8.013AlaAsp: 8.013 ± 0.054	7.761AlaGlu: 7.761 ± 0.071	3.555AlaPhe: 3.555 ± 0.035	14.967AlaGly: 14.967 ± 0.103	2.637AlaHis: 2.637 ± 0.03	4.287AlaIle: 4.287 ± 0.045	2.264AlaLys: 2.264 ± 0.035	14.272AlaLeu: 14.272 ± 0.081	2.572AlaMet: 2.572 ± 0.026	2.233AlaAsn: 2.233 ± 0.034	7.182AlaPro: 7.182 ± 0.057	3.542AlaGln: 3.542 ± 0.038	10.986AlaArg: 10.986 ± 0.079	6.345AlaSer: 6.345 ± 0.049	8.013AlaThr: 8.013 ± 0.064	12.937AlaVal: 12.937 ± 0.085	2.021AlaTrp: 2.021 ± 0.03	2.811AlaTyr: 2.811 ± 0.034	0.0AlaXaa: 0.0 ± 0.0
Cys	1.077CysAla: 1.077 ± 0.019	0.141CysCys: 0.141 ± 0.007	0.498CysAsp: 0.498 ± 0.012	0.346CysGlu: 0.346 ± 0.012	0.215CysPhe: 0.215 ± 0.009	1.012CysGly: 1.012 ± 0.019	0.208CysHis: 0.208 ± 0.008	0.136CysIle: 0.136 ± 0.008	0.092CysLys: 0.092 ± 0.006	0.714CysLeu: 0.714 ± 0.016	0.125CysMet: 0.125 ± 0.007	0.124CysAsn: 0.124 ± 0.006	0.519CysPro: 0.519 ± 0.016	0.212CysGln: 0.212 ± 0.009	0.734CysArg: 0.734 ± 0.017	0.466CysSer: 0.466 ± 0.015	0.479CysThr: 0.479 ± 0.012	0.663CysVal: 0.663 ± 0.015	0.166CysTrp: 0.166 ± 0.009	0.168CysTyr: 0.168 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	7.386AspAla: 7.386 ± 0.058	0.377AspCys: 0.377 ± 0.013	3.5AspAsp: 3.5 ± 0.045	3.68AspGlu: 3.68 ± 0.043	1.558AspPhe: 1.558 ± 0.026	6.369AspGly: 6.369 ± 0.054	1.337AspHis: 1.337 ± 0.023	1.766AspIle: 1.766 ± 0.025	0.901AspLys: 0.901 ± 0.017	6.821AspLeu: 6.821 ± 0.052	0.736AspMet: 0.736 ± 0.015	0.969AspAsn: 0.969 ± 0.018	4.711AspPro: 4.711 ± 0.051	1.653AspGln: 1.653 ± 0.025	5.349AspArg: 5.349 ± 0.055	2.195AspSer: 2.195 ± 0.032	2.804AspThr: 2.804 ± 0.037	4.831AspVal: 4.831 ± 0.043	0.941AspTrp: 0.941 ± 0.019	1.118AspTyr: 1.118 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	6.815GluAla: 6.815 ± 0.055	0.346GluCys: 0.346 ± 0.012	2.141GluAsp: 2.141 ± 0.034	2.567GluGlu: 2.567 ± 0.037	1.433GluPhe: 1.433 ± 0.022	3.549GluGly: 3.549 ± 0.042	1.329GluHis: 1.329 ± 0.024	2.096GluIle: 2.096 ± 0.029	0.952GluLys: 0.952 ± 0.021	5.839GluLeu: 5.839 ± 0.057	0.83GluMet: 0.83 ± 0.017	0.741GluAsn: 0.741 ± 0.016	3.461GluPro: 3.461 ± 0.044	1.891GluGln: 1.891 ± 0.028	5.388GluArg: 5.388 ± 0.051	2.248GluSer: 2.248 ± 0.024	2.458GluThr: 2.458 ± 0.03	4.708GluVal: 4.708 ± 0.045	0.752GluTrp: 0.752 ± 0.013	1.061GluTyr: 1.061 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	3.85PheAla: 3.85 ± 0.039	0.238PheCys: 0.238 ± 0.009	2.069PheAsp: 2.069 ± 0.028	1.372PheGlu: 1.372 ± 0.022	0.868PhePhe: 0.868 ± 0.021	3.036PheGly: 3.036 ± 0.036	0.58PheHis: 0.58 ± 0.014	0.695PheIle: 0.695 ± 0.016	0.407PheLys: 0.407 ± 0.012	2.418PheLeu: 2.418 ± 0.032	0.369PheMet: 0.369 ± 0.012	0.585PheAsn: 0.585 ± 0.015	1.346PhePro: 1.346 ± 0.019	0.742PheGln: 0.742 ± 0.018	1.822PheArg: 1.822 ± 0.027	1.344PheSer: 1.344 ± 0.021	1.885PheThr: 1.885 ± 0.026	2.486PheVal: 2.486 ± 0.03	0.433PheTrp: 0.433 ± 0.011	0.603PheTyr: 0.603 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	11.49GlyAla: 11.49 ± 0.08	0.878GlyCys: 0.878 ± 0.017	5.42GlyAsp: 5.42 ± 0.051	4.823GlyGlu: 4.823 ± 0.048	2.892GlyPhe: 2.892 ± 0.04	9.582GlyGly: 9.582 ± 0.088	2.191GlyHis: 2.191 ± 0.027	3.338GlyIle: 3.338 ± 0.04	1.808GlyLys: 1.808 ± 0.029	9.296GlyLeu: 9.296 ± 0.062	1.911GlyMet: 1.911 ± 0.025	1.741GlyAsn: 1.741 ± 0.031	5.378GlyPro: 5.378 ± 0.05	2.924GlyGln: 2.924 ± 0.036	8.111GlyArg: 8.111 ± 0.062	5.061GlySer: 5.061 ± 0.049	5.982GlyThr: 5.982 ± 0.065	8.158GlyVal: 8.158 ± 0.062	1.939GlyTrp: 1.939 ± 0.022	2.415GlyTyr: 2.415 ± 0.031	0.0GlyXaa: 0.0 ± 0.0
His	2.564HisAla: 2.564 ± 0.036	0.196HisCys: 0.196 ± 0.008	1.284HisAsp: 1.284 ± 0.021	1.074HisGlu: 1.074 ± 0.02	0.568HisPhe: 0.568 ± 0.014	2.117HisGly: 2.117 ± 0.028	0.642HisHis: 0.642 ± 0.019	0.597HisIle: 0.597 ± 0.014	0.278HisLys: 0.278 ± 0.01	2.448HisLeu: 2.448 ± 0.032	0.303HisMet: 0.303 ± 0.011	0.383HisAsn: 0.383 ± 0.011	1.765HisPro: 1.765 ± 0.028	0.611HisGln: 0.611 ± 0.016	2.067HisArg: 2.067 ± 0.029	0.941HisSer: 0.941 ± 0.016	1.164HisThr: 1.164 ± 0.024	1.697HisVal: 1.697 ± 0.026	0.329HisTrp: 0.329 ± 0.01	0.442HisTyr: 0.442 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	4.833IleAla: 4.833 ± 0.048	0.296IleCys: 0.296 ± 0.011	2.274IleAsp: 2.274 ± 0.028	1.938IleGlu: 1.938 ± 0.024	0.828IlePhe: 0.828 ± 0.019	3.429IleGly: 3.429 ± 0.038	0.616IleHis: 0.616 ± 0.015	0.872IleIle: 0.872 ± 0.023	0.607IleLys: 0.607 ± 0.017	2.525IleLeu: 2.525 ± 0.033	0.455IleMet: 0.455 ± 0.012	0.692IleAsn: 0.692 ± 0.016	1.717IlePro: 1.717 ± 0.027	0.754IleGln: 0.754 ± 0.018	2.436IleArg: 2.436 ± 0.027	1.688IleSer: 1.688 ± 0.025	1.964IleThr: 1.964 ± 0.032	2.955IleVal: 2.955 ± 0.039	0.417IleTrp: 0.417 ± 0.014	0.609IleTyr: 0.609 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	2.226LysAla: 2.226 ± 0.032	0.095LysCys: 0.095 ± 0.006	0.794LysAsp: 0.794 ± 0.018	0.774LysGlu: 0.774 ± 0.02	0.354LysPhe: 0.354 ± 0.012	1.278LysGly: 1.278 ± 0.022	0.339LysHis: 0.339 ± 0.011	0.685LysIle: 0.685 ± 0.018	0.428LysLys: 0.428 ± 0.014	1.656LysLeu: 1.656 ± 0.028	0.306LysMet: 0.306 ± 0.01	0.31LysAsn: 0.31 ± 0.013	1.099LysPro: 1.099 ± 0.023	0.536LysGln: 0.536 ± 0.014	1.264LysArg: 1.264 ± 0.023	0.808LysSer: 0.808 ± 0.017	0.973LysThr: 0.973 ± 0.02	1.603LysVal: 1.603 ± 0.024	0.238LysTrp: 0.238 ± 0.01	0.332LysTyr: 0.332 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	16.338LeuAla: 16.338 ± 0.095	0.775LeuCys: 0.775 ± 0.017	6.952LeuAsp: 6.952 ± 0.062	4.045LeuGlu: 4.045 ± 0.044	2.549LeuPhe: 2.549 ± 0.036	9.066LeuGly: 9.066 ± 0.069	2.082LeuHis: 2.082 ± 0.028	2.948LeuIle: 2.948 ± 0.038	1.432LeuLys: 1.432 ± 0.026	10.652LeuLeu: 10.652 ± 0.084	1.479LeuMet: 1.479 ± 0.021	1.601LeuAsn: 1.601 ± 0.027	6.346LeuPro: 6.346 ± 0.049	1.906LeuGln: 1.906 ± 0.029	9.052LeuArg: 9.052 ± 0.065	5.22LeuSer: 5.22 ± 0.043	6.262LeuThr: 6.262 ± 0.052	9.642LeuVal: 9.642 ± 0.068	1.309LeuTrp: 1.309 ± 0.025	1.759LeuTyr: 1.759 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.242MetAla: 2.242 ± 0.028	0.134MetCys: 0.134 ± 0.008	0.814MetAsp: 0.814 ± 0.018	0.641MetGlu: 0.641 ± 0.015	0.5MetPhe: 0.5 ± 0.014	1.224MetGly: 1.224 ± 0.023	0.319MetHis: 0.319 ± 0.011	0.654MetIle: 0.654 ± 0.014	0.32MetLys: 0.32 ± 0.01	1.808MetLeu: 1.808 ± 0.029	0.27MetMet: 0.27 ± 0.009	0.338MetAsn: 0.338 ± 0.012	1.114MetPro: 1.114 ± 0.021	0.388MetGln: 0.388 ± 0.011	1.557MetArg: 1.557 ± 0.026	1.222MetSer: 1.222 ± 0.021	1.434MetThr: 1.434 ± 0.023	1.417MetVal: 1.417 ± 0.02	0.254MetTrp: 0.254 ± 0.011	0.299MetTyr: 0.299 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.226AsnAla: 2.226 ± 0.032	0.163AsnCys: 0.163 ± 0.008	0.937AsnAsp: 0.937 ± 0.019	0.788AsnGlu: 0.788 ± 0.018	0.521AsnPhe: 0.521 ± 0.014	1.928AsnGly: 1.928 ± 0.036	0.378AsnHis: 0.378 ± 0.012	0.598AsnIle: 0.598 ± 0.016	0.308AsnLys: 0.308 ± 0.01	1.73AsnLeu: 1.73 ± 0.024	0.265AsnMet: 0.265 ± 0.009	0.474AsnAsn: 0.474 ± 0.015	1.417AsnPro: 1.417 ± 0.026	0.581AsnGln: 0.581 ± 0.017	1.312AsnArg: 1.312 ± 0.023	0.867AsnSer: 0.867 ± 0.02	1.031AsnThr: 1.031 ± 0.023	1.426AsnVal: 1.426 ± 0.024	0.296AsnTrp: 0.296 ± 0.011	0.437AsnTyr: 0.437 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	9.83ProAla: 9.83 ± 0.08	0.359ProCys: 0.359 ± 0.013	4.705ProAsp: 4.705 ± 0.049	3.705ProGlu: 3.705 ± 0.036	1.544ProPhe: 1.544 ± 0.023	6.608ProGly: 6.608 ± 0.063	1.263ProHis: 1.263 ± 0.025	1.668ProIle: 1.668 ± 0.026	0.912ProLys: 0.912 ± 0.019	5.101ProLeu: 5.101 ± 0.045	1.082ProMet: 1.082 ± 0.018	1.038ProAsn: 1.038 ± 0.022	4.797ProPro: 4.797 ± 0.072	1.493ProGln: 1.493 ± 0.026	4.582ProArg: 4.582 ± 0.051	3.42ProSer: 3.42 ± 0.038	3.737ProThr: 3.737 ± 0.047	5.579ProVal: 5.579 ± 0.054	0.976ProTrp: 0.976 ± 0.017	1.312ProTyr: 1.312 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.614GlnAla: 3.614 ± 0.04	0.16GlnCys: 0.16 ± 0.007	1.134GlnAsp: 1.134 ± 0.02	1.156GlnGlu: 1.156 ± 0.021	0.71GlnPhe: 0.71 ± 0.016	1.895GlnGly: 1.895 ± 0.026	0.615GlnHis: 0.615 ± 0.018	1.14GlnIle: 1.14 ± 0.02	0.443GlnLys: 0.443 ± 0.013	3.005GlnLeu: 3.005 ± 0.034	0.47GlnMet: 0.47 ± 0.014	0.433GlnAsn: 0.433 ± 0.015	1.9GlnPro: 1.9 ± 0.03	1.061GlnGln: 1.061 ± 0.024	2.689GlnArg: 2.689 ± 0.03	1.18GlnSer: 1.18 ± 0.022	1.365GlnThr: 1.365 ± 0.025	2.641GlnVal: 2.641 ± 0.031	0.517GlnTrp: 0.517 ± 0.016	0.542GlnTyr: 0.542 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	10.638ArgAla: 10.638 ± 0.076	0.782ArgCys: 0.782 ± 0.017	4.751ArgAsp: 4.751 ± 0.045	4.472ArgGlu: 4.472 ± 0.045	2.5ArgPhe: 2.5 ± 0.03	6.377ArgGly: 6.377 ± 0.061	2.232ArgHis: 2.232 ± 0.032	3.069ArgIle: 3.069 ± 0.036	1.285ArgLys: 1.285 ± 0.022	9.378ArgLeu: 9.378 ± 0.065	1.849ArgMet: 1.849 ± 0.027	1.349ArgAsn: 1.349 ± 0.023	5.639ArgPro: 5.639 ± 0.059	2.612ArgGln: 2.612 ± 0.031	9.166ArgArg: 9.166 ± 0.081	4.43ArgSer: 4.43 ± 0.048	4.893ArgThr: 4.893 ± 0.044	6.752ArgVal: 6.752 ± 0.05	1.763ArgTrp: 1.763 ± 0.028	2.1ArgTyr: 2.1 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	6.526SerAla: 6.526 ± 0.056	0.491SerCys: 0.491 ± 0.015	2.403SerAsp: 2.403 ± 0.029	1.952SerGlu: 1.952 ± 0.031	1.48SerPhe: 1.48 ± 0.021	5.917SerGly: 5.917 ± 0.064	0.949SerHis: 0.949 ± 0.019	1.623SerIle: 1.623 ± 0.024	0.769SerLys: 0.769 ± 0.017	4.533SerLeu: 4.533 ± 0.043	1.078SerMet: 1.078 ± 0.02	0.905SerAsn: 0.905 ± 0.019	3.505SerPro: 3.505 ± 0.038	1.237SerGln: 1.237 ± 0.021	4.109SerArg: 4.109 ± 0.036	2.901SerSer: 2.901 ± 0.037	3.392SerThr: 3.392 ± 0.038	4.093SerVal: 4.093 ± 0.041	1.022SerTrp: 1.022 ± 0.022	1.19SerTyr: 1.19 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	8.475ThrAla: 8.475 ± 0.057	0.495ThrCys: 0.495 ± 0.013	3.202ThrAsp: 3.202 ± 0.036	2.628ThrGlu: 2.628 ± 0.033	1.658ThrPhe: 1.658 ± 0.026	6.495ThrGly: 6.495 ± 0.062	1.094ThrHis: 1.094 ± 0.022	1.954ThrIle: 1.954 ± 0.028	0.911ThrLys: 0.911 ± 0.019	5.657ThrLeu: 5.657 ± 0.053	1.028ThrMet: 1.028 ± 0.02	1.165ThrAsn: 1.165 ± 0.025	4.145ThrPro: 4.145 ± 0.049	1.337ThrGln: 1.337 ± 0.021	4.307ThrArg: 4.307 ± 0.046	3.197ThrSer: 3.197 ± 0.034	3.88ThrThr: 3.88 ± 0.055	6.105ThrVal: 6.105 ± 0.054	1.006ThrTrp: 1.006 ± 0.022	1.298ThrTyr: 1.298 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	12.864ValAla: 12.864 ± 0.081	0.698ValCys: 0.698 ± 0.016	5.93ValAsp: 5.93 ± 0.049	5.054ValGlu: 5.054 ± 0.042	2.339ValPhe: 2.339 ± 0.026	7.244ValGly: 7.244 ± 0.062	1.794ValHis: 1.794 ± 0.024	2.744ValIle: 2.744 ± 0.035	1.401ValLys: 1.401 ± 0.025	9.392ValLeu: 9.392 ± 0.076	1.307ValMet: 1.307 ± 0.025	1.752ValAsn: 1.752 ± 0.029	5.408ValPro: 5.408 ± 0.052	1.926ValGln: 1.926 ± 0.026	7.484ValArg: 7.484 ± 0.055	4.461ValSer: 4.461 ± 0.044	5.963ValThr: 5.963 ± 0.053	8.918ValVal: 8.918 ± 0.066	1.151ValTrp: 1.151 ± 0.021	1.647ValTyr: 1.647 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	1.746TrpAla: 1.746 ± 0.025	0.191TrpCys: 0.191 ± 0.008	0.807TrpAsp: 0.807 ± 0.019	0.684TrpGlu: 0.684 ± 0.017	0.48TrpPhe: 0.48 ± 0.012	1.067TrpGly: 1.067 ± 0.022	0.407TrpHis: 0.407 ± 0.011	0.549TrpIle: 0.549 ± 0.012	0.254TrpLys: 0.254 ± 0.009	1.936TrpLeu: 1.936 ± 0.026	0.293TrpMet: 0.293 ± 0.01	0.406TrpAsn: 0.406 ± 0.014	1.039TrpPro: 1.039 ± 0.022	0.613TrpGln: 0.613 ± 0.014	1.713TrpArg: 1.713 ± 0.028	1.088TrpSer: 1.088 ± 0.021	1.125TrpThr: 1.125 ± 0.023	1.123TrpVal: 1.123 ± 0.02	0.386TrpTrp: 0.386 ± 0.012	0.385TrpTyr: 0.385 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.75TyrAla: 2.75 ± 0.032	0.187TyrCys: 0.187 ± 0.008	1.375TyrAsp: 1.375 ± 0.024	1.144TyrGlu: 1.144 ± 0.021	0.596TyrPhe: 0.596 ± 0.015	2.18TyrGly: 2.18 ± 0.028	0.458TyrHis: 0.458 ± 0.014	0.479TyrIle: 0.479 ± 0.014	0.326TyrLys: 0.326 ± 0.01	2.233TyrLeu: 2.233 ± 0.031	0.218TyrMet: 0.218 ± 0.009	0.445TyrAsn: 0.445 ± 0.012	1.226TyrPro: 1.226 ± 0.022	0.652TyrGln: 0.652 ± 0.015	1.909TyrArg: 1.909 ± 0.029	0.994TyrSer: 0.994 ± 0.018	1.232TyrThr: 1.232 ± 0.025	1.745TyrVal: 1.745 ± 0.028	0.378TyrTrp: 0.378 ± 0.011	0.453TyrTyr: 0.453 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9401 proteins (2924729 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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