Amino acid dipepetide frequency for Plesiomonas shigelloides 302-73

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.174AlaAla: 11.174 ± 0.159	1.216AlaCys: 1.216 ± 0.041	5.583AlaAsp: 5.583 ± 0.079	6.539AlaGlu: 6.539 ± 0.091	3.507AlaPhe: 3.507 ± 0.062	7.473AlaGly: 7.473 ± 0.108	2.09AlaHis: 2.09 ± 0.044	5.416AlaIle: 5.416 ± 0.083	3.899AlaLys: 3.899 ± 0.081	12.536AlaLeu: 12.536 ± 0.136	2.995AlaMet: 2.995 ± 0.061	3.273AlaAsn: 3.273 ± 0.057	3.978AlaPro: 3.978 ± 0.074	5.381AlaGln: 5.381 ± 0.083	5.638AlaArg: 5.638 ± 0.088	5.5AlaSer: 5.5 ± 0.078	4.682AlaThr: 4.682 ± 0.065	6.954AlaVal: 6.954 ± 0.093	1.208AlaTrp: 1.208 ± 0.039	2.438AlaTyr: 2.438 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.108CysAla: 1.108 ± 0.031	0.201CysCys: 0.201 ± 0.016	0.598CysAsp: 0.598 ± 0.024	0.62CysGlu: 0.62 ± 0.025	0.434CysPhe: 0.434 ± 0.021	1.114CysGly: 1.114 ± 0.036	0.362CysHis: 0.362 ± 0.02	0.572CysIle: 0.572 ± 0.026	0.301CysLys: 0.301 ± 0.02	1.098CysLeu: 1.098 ± 0.033	0.256CysMet: 0.256 ± 0.015	0.331CysAsn: 0.331 ± 0.018	0.542CysPro: 0.542 ± 0.023	0.582CysGln: 0.582 ± 0.023	0.725CysArg: 0.725 ± 0.03	0.652CysSer: 0.652 ± 0.022	0.544CysThr: 0.544 ± 0.023	0.753CysVal: 0.753 ± 0.026	0.186CysTrp: 0.186 ± 0.012	0.369CysTyr: 0.369 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	5.11AspAla: 5.11 ± 0.079	0.582AspCys: 0.582 ± 0.02	2.749AspAsp: 2.749 ± 0.067	3.3AspGlu: 3.3 ± 0.061	2.105AspPhe: 2.105 ± 0.047	3.725AspGly: 3.725 ± 0.06	1.01AspHis: 1.01 ± 0.031	3.289AspIle: 3.289 ± 0.053	2.447AspLys: 2.447 ± 0.045	5.128AspLeu: 5.128 ± 0.065	1.459AspMet: 1.459 ± 0.039	2.077AspAsn: 2.077 ± 0.044	2.425AspPro: 2.425 ± 0.052	1.882AspGln: 1.882 ± 0.047	2.455AspArg: 2.455 ± 0.056	3.077AspSer: 3.077 ± 0.059	2.593AspThr: 2.593 ± 0.048	3.747AspVal: 3.747 ± 0.071	0.772AspTrp: 0.772 ± 0.029	1.767AspTyr: 1.767 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	5.124GluAla: 5.124 ± 0.085	0.559GluCys: 0.559 ± 0.024	2.142GluAsp: 2.142 ± 0.053	3.098GluGlu: 3.098 ± 0.067	2.006GluPhe: 2.006 ± 0.042	3.221GluGly: 3.221 ± 0.06	1.527GluHis: 1.527 ± 0.034	3.154GluIle: 3.154 ± 0.06	2.67GluLys: 2.67 ± 0.057	6.537GluLeu: 6.537 ± 0.091	1.75GluMet: 1.75 ± 0.045	2.01GluAsn: 2.01 ± 0.039	2.264GluPro: 2.264 ± 0.052	4.347GluGln: 4.347 ± 0.083	3.927GluArg: 3.927 ± 0.079	2.906GluSer: 2.906 ± 0.058	2.635GluThr: 2.635 ± 0.055	3.665GluVal: 3.665 ± 0.07	0.742GluTrp: 0.742 ± 0.026	1.554GluTyr: 1.554 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.83PheAla: 3.83 ± 0.061	0.541PheCys: 0.541 ± 0.025	2.289PheAsp: 2.289 ± 0.054	1.766PheGlu: 1.766 ± 0.049	1.574PhePhe: 1.574 ± 0.048	3.055PheGly: 3.055 ± 0.057	0.81PheHis: 0.81 ± 0.031	2.392PheIle: 2.392 ± 0.053	1.278PheLys: 1.278 ± 0.036	3.256PheLeu: 3.256 ± 0.061	0.949PheMet: 0.949 ± 0.031	1.625PheAsn: 1.625 ± 0.041	1.391PhePro: 1.391 ± 0.035	1.098PheGln: 1.098 ± 0.027	1.822PheArg: 1.822 ± 0.043	2.942PheSer: 2.942 ± 0.057	2.244PheThr: 2.244 ± 0.049	2.486PheVal: 2.486 ± 0.054	0.53PheTrp: 0.53 ± 0.025	1.237PheTyr: 1.237 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	6.101GlyAla: 6.101 ± 0.106	0.975GlyCys: 0.975 ± 0.031	3.479GlyAsp: 3.479 ± 0.059	4.248GlyGlu: 4.248 ± 0.08	3.089GlyPhe: 3.089 ± 0.061	4.969GlyGly: 4.969 ± 0.104	1.648GlyHis: 1.648 ± 0.044	4.728GlyIle: 4.728 ± 0.076	3.539GlyLys: 3.539 ± 0.062	7.512GlyLeu: 7.512 ± 0.106	2.328GlyMet: 2.328 ± 0.049	2.567GlyAsn: 2.567 ± 0.06	1.902GlyPro: 1.902 ± 0.049	3.35GlyGln: 3.35 ± 0.066	3.733GlyArg: 3.733 ± 0.063	4.167GlySer: 4.167 ± 0.075	3.369GlyThr: 3.369 ± 0.065	5.505GlyVal: 5.505 ± 0.086	1.168GlyTrp: 1.168 ± 0.036	2.524GlyTyr: 2.524 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.214HisAla: 2.214 ± 0.044	0.412HisCys: 0.412 ± 0.02	1.233HisAsp: 1.233 ± 0.036	1.149HisGlu: 1.149 ± 0.031	1.016HisPhe: 1.016 ± 0.031	1.809HisGly: 1.809 ± 0.046	0.686HisHis: 0.686 ± 0.029	1.333HisIle: 1.333 ± 0.034	0.82HisLys: 0.82 ± 0.027	2.445HisLeu: 2.445 ± 0.051	0.554HisMet: 0.554 ± 0.025	0.863HisAsn: 0.863 ± 0.028	1.408HisPro: 1.408 ± 0.038	1.197HisGln: 1.197 ± 0.037	1.271HisArg: 1.271 ± 0.038	1.387HisSer: 1.387 ± 0.035	1.214HisThr: 1.214 ± 0.033	1.321HisVal: 1.321 ± 0.029	0.426HisTrp: 0.426 ± 0.02	0.894HisTyr: 0.894 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.136IleAla: 6.136 ± 0.088	0.706IleCys: 0.706 ± 0.031	3.277IleAsp: 3.277 ± 0.055	3.25IleGlu: 3.25 ± 0.058	1.925IlePhe: 1.925 ± 0.046	4.527IleGly: 4.527 ± 0.082	1.171IleHis: 1.171 ± 0.031	3.019IleIle: 3.019 ± 0.066	2.24IleLys: 2.24 ± 0.063	4.945IleLeu: 4.945 ± 0.078	1.166IleMet: 1.166 ± 0.034	2.353IleAsn: 2.353 ± 0.057	2.72IlePro: 2.72 ± 0.05	2.0IleGln: 2.0 ± 0.048	3.291IleArg: 3.291 ± 0.055	3.771IleSer: 3.771 ± 0.069	3.373IleThr: 3.373 ± 0.06	3.509IleVal: 3.509 ± 0.066	0.581IleTrp: 0.581 ± 0.025	1.513IleTyr: 1.513 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.007LysAla: 4.007 ± 0.069	0.243LysCys: 0.243 ± 0.015	1.93LysAsp: 1.93 ± 0.043	2.282LysGlu: 2.282 ± 0.055	1.07LysPhe: 1.07 ± 0.033	2.552LysGly: 2.552 ± 0.056	0.792LysHis: 0.792 ± 0.032	2.281LysIle: 2.281 ± 0.052	1.968LysLys: 1.968 ± 0.053	4.143LysLeu: 4.143 ± 0.062	1.052LysMet: 1.052 ± 0.035	1.649LysAsn: 1.649 ± 0.031	2.104LysPro: 2.104 ± 0.05	2.048LysGln: 2.048 ± 0.046	2.204LysArg: 2.204 ± 0.055	2.18LysSer: 2.18 ± 0.049	2.275LysThr: 2.275 ± 0.05	3.01LysVal: 3.01 ± 0.065	0.41LysTrp: 0.41 ± 0.021	1.046LysTyr: 1.046 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	11.961LeuAla: 11.961 ± 0.119	1.375LeuCys: 1.375 ± 0.04	5.733LeuAsp: 5.733 ± 0.082	5.462LeuGlu: 5.462 ± 0.095	4.149LeuPhe: 4.149 ± 0.073	7.565LeuGly: 7.565 ± 0.1	2.662LeuHis: 2.662 ± 0.052	5.627LeuIle: 5.627 ± 0.089	4.017LeuLys: 4.017 ± 0.065	13.387LeuLeu: 13.387 ± 0.165	2.979LeuMet: 2.979 ± 0.057	4.186LeuAsn: 4.186 ± 0.06	5.991LeuPro: 5.991 ± 0.082	5.619LeuGln: 5.619 ± 0.104	6.506LeuArg: 6.506 ± 0.092	7.846LeuSer: 7.846 ± 0.096	6.623LeuThr: 6.623 ± 0.089	7.044LeuVal: 7.044 ± 0.089	1.35LeuTrp: 1.35 ± 0.045	2.69LeuTyr: 2.69 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.82MetAla: 2.82 ± 0.056	0.215MetCys: 0.215 ± 0.013	1.193MetAsp: 1.193 ± 0.03	1.157MetGlu: 1.157 ± 0.036	0.848MetPhe: 0.848 ± 0.031	1.752MetGly: 1.752 ± 0.045	0.559MetHis: 0.559 ± 0.025	1.367MetIle: 1.367 ± 0.041	1.175MetLys: 1.175 ± 0.033	3.366MetLeu: 3.366 ± 0.055	0.82MetMet: 0.82 ± 0.033	0.979MetAsn: 0.979 ± 0.029	1.381MetPro: 1.381 ± 0.035	1.526MetGln: 1.526 ± 0.036	1.409MetArg: 1.409 ± 0.039	1.831MetSer: 1.831 ± 0.04	1.679MetThr: 1.679 ± 0.04	1.83MetVal: 1.83 ± 0.041	0.223MetTrp: 0.223 ± 0.013	0.504MetTyr: 0.504 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.548AsnAla: 3.548 ± 0.06	0.327AsnCys: 0.327 ± 0.019	1.825AsnAsp: 1.825 ± 0.051	1.779AsnGlu: 1.779 ± 0.037	1.183AsnPhe: 1.183 ± 0.032	2.803AsnGly: 2.803 ± 0.06	0.818AsnHis: 0.818 ± 0.026	2.144AsnIle: 2.144 ± 0.053	1.52AsnLys: 1.52 ± 0.041	3.619AsnLeu: 3.619 ± 0.059	0.874AsnMet: 0.874 ± 0.027	1.527AsnAsn: 1.527 ± 0.045	2.288AsnPro: 2.288 ± 0.044	1.797AsnGln: 1.797 ± 0.042	2.015AsnArg: 2.015 ± 0.051	2.045AsnSer: 2.045 ± 0.056	1.908AsnThr: 1.908 ± 0.043	2.324AsnVal: 2.324 ± 0.051	0.529AsnTrp: 0.529 ± 0.024	1.083AsnTyr: 1.083 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	5.033ProAla: 5.033 ± 0.087	0.411ProCys: 0.411 ± 0.02	2.853ProAsp: 2.853 ± 0.057	3.279ProGlu: 3.279 ± 0.063	1.756ProPhe: 1.756 ± 0.044	2.693ProGly: 2.693 ± 0.049	1.166ProHis: 1.166 ± 0.035	1.95ProIle: 1.95 ± 0.043	1.574ProLys: 1.574 ± 0.041	5.24ProLeu: 5.24 ± 0.078	1.045ProMet: 1.045 ± 0.034	1.459ProAsn: 1.459 ± 0.047	1.496ProPro: 1.496 ± 0.041	2.514ProGln: 2.514 ± 0.058	1.909ProArg: 1.909 ± 0.046	2.599ProSer: 2.599 ± 0.056	2.267ProThr: 2.267 ± 0.049	4.021ProVal: 4.021 ± 0.07	0.608ProTrp: 0.608 ± 0.023	1.326ProTyr: 1.326 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	5.976GlnAla: 5.976 ± 0.102	0.447GlnCys: 0.447 ± 0.022	2.208GlnAsp: 2.208 ± 0.045	2.534GlnGlu: 2.534 ± 0.05	1.578GlnPhe: 1.578 ± 0.038	3.585GlnGly: 3.585 ± 0.066	1.559GlnHis: 1.559 ± 0.041	2.75GlnIle: 2.75 ± 0.049	1.807GlnLys: 1.807 ± 0.044	5.8GlnLeu: 5.8 ± 0.09	1.343GlnMet: 1.343 ± 0.032	1.507GlnAsn: 1.507 ± 0.04	2.497GlnPro: 2.497 ± 0.055	4.286GlnGln: 4.286 ± 0.094	3.324GlnArg: 3.324 ± 0.069	2.54GlnSer: 2.54 ± 0.048	2.579GlnThr: 2.579 ± 0.052	3.539GlnVal: 3.539 ± 0.05	0.791GlnTrp: 0.791 ± 0.03	1.349GlnTyr: 1.349 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	4.876ArgAla: 4.876 ± 0.069	0.665ArgCys: 0.665 ± 0.027	3.033ArgAsp: 3.033 ± 0.055	3.6ArgGlu: 3.6 ± 0.069	2.498ArgPhe: 2.498 ± 0.054	3.394ArgGly: 3.394 ± 0.066	1.613ArgHis: 1.613 ± 0.044	3.362ArgIle: 3.362 ± 0.063	2.175ArgLys: 2.175 ± 0.052	6.616ArgLeu: 6.616 ± 0.102	1.441ArgMet: 1.441 ± 0.035	2.002ArgAsn: 2.002 ± 0.047	2.261ArgPro: 2.261 ± 0.045	3.309ArgGln: 3.309 ± 0.061	3.626ArgArg: 3.626 ± 0.075	2.944ArgSer: 2.944 ± 0.06	2.544ArgThr: 2.544 ± 0.048	3.658ArgVal: 3.658 ± 0.063	1.014ArgTrp: 1.014 ± 0.036	2.161ArgTyr: 2.161 ± 0.054	0.0ArgXaa: 0.0 ± 0.0
Ser	6.559SerAla: 6.559 ± 0.093	0.579SerCys: 0.579 ± 0.022	3.091SerAsp: 3.091 ± 0.05	3.432SerGlu: 3.432 ± 0.065	2.252SerPhe: 2.252 ± 0.049	5.091SerGly: 5.091 ± 0.076	1.448SerHis: 1.448 ± 0.033	3.125SerIle: 3.125 ± 0.069	2.172SerLys: 2.172 ± 0.048	6.679SerLeu: 6.679 ± 0.078	1.523SerMet: 1.523 ± 0.046	1.993SerAsn: 1.993 ± 0.048	2.491SerPro: 2.491 ± 0.056	2.741SerGln: 2.741 ± 0.052	3.438SerArg: 3.438 ± 0.06	3.77SerSer: 3.77 ± 0.068	2.97SerThr: 2.97 ± 0.063	4.438SerVal: 4.438 ± 0.067	0.873SerTrp: 0.873 ± 0.027	1.606SerTyr: 1.606 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	5.284ThrAla: 5.284 ± 0.084	0.531ThrCys: 0.531 ± 0.025	2.793ThrAsp: 2.793 ± 0.055	2.973ThrGlu: 2.973 ± 0.059	1.803ThrPhe: 1.803 ± 0.041	4.16ThrGly: 4.16 ± 0.063	1.208ThrHis: 1.208 ± 0.039	2.619ThrIle: 2.619 ± 0.051	1.609ThrLys: 1.609 ± 0.044	7.196ThrLeu: 7.196 ± 0.085	1.003ThrMet: 1.003 ± 0.033	1.511ThrAsn: 1.511 ± 0.04	3.087ThrPro: 3.087 ± 0.057	2.366ThrGln: 2.366 ± 0.049	2.76ThrArg: 2.76 ± 0.05	2.842ThrSer: 2.842 ± 0.057	2.665ThrThr: 2.665 ± 0.057	3.723ThrVal: 3.723 ± 0.056	0.603ThrTrp: 0.603 ± 0.025	1.308ThrTyr: 1.308 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	6.993ValAla: 6.993 ± 0.098	0.822ValCys: 0.822 ± 0.026	3.597ValAsp: 3.597 ± 0.065	3.691ValGlu: 3.691 ± 0.065	2.564ValPhe: 2.564 ± 0.051	4.614ValGly: 4.614 ± 0.072	1.294ValHis: 1.294 ± 0.036	4.315ValIle: 4.315 ± 0.062	2.722ValLys: 2.722 ± 0.064	7.723ValLeu: 7.723 ± 0.095	2.11ValMet: 2.11 ± 0.047	2.583ValAsn: 2.583 ± 0.058	2.868ValPro: 2.868 ± 0.052	2.822ValGln: 2.822 ± 0.053	3.832ValArg: 3.832 ± 0.072	4.737ValSer: 4.737 ± 0.066	4.015ValThr: 4.015 ± 0.072	5.344ValVal: 5.344 ± 0.089	0.897ValTrp: 0.897 ± 0.027	1.879ValTyr: 1.879 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.012TrpAla: 1.012 ± 0.035	0.173TrpCys: 0.173 ± 0.013	0.62TrpAsp: 0.62 ± 0.025	0.527TrpGlu: 0.527 ± 0.023	0.567TrpPhe: 0.567 ± 0.024	0.797TrpGly: 0.797 ± 0.028	0.38TrpHis: 0.38 ± 0.017	0.653TrpIle: 0.653 ± 0.024	0.415TrpLys: 0.415 ± 0.019	2.205TrpLeu: 2.205 ± 0.056	0.366TrpMet: 0.366 ± 0.02	0.46TrpAsn: 0.46 ± 0.025	0.629TrpPro: 0.629 ± 0.025	1.218TrpGln: 1.218 ± 0.039	0.911TrpArg: 0.911 ± 0.028	0.738TrpSer: 0.738 ± 0.024	0.46TrpThr: 0.46 ± 0.025	0.88TrpVal: 0.88 ± 0.029	0.251TrpTrp: 0.251 ± 0.015	0.389TrpTyr: 0.389 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.616TyrAla: 2.616 ± 0.05	0.368TyrCys: 0.368 ± 0.02	1.473TyrAsp: 1.473 ± 0.042	1.15TyrGlu: 1.15 ± 0.036	1.189TyrPhe: 1.189 ± 0.034	2.003TyrGly: 2.003 ± 0.051	0.85TyrHis: 0.85 ± 0.031	1.377TyrIle: 1.377 ± 0.037	0.897TyrLys: 0.897 ± 0.03	3.341TyrLeu: 3.341 ± 0.063	0.622TyrMet: 0.622 ± 0.028	1.002TyrAsn: 1.002 ± 0.032	1.475TyrPro: 1.475 ± 0.041	1.915TyrGln: 1.915 ± 0.044	1.998TyrArg: 1.998 ± 0.048	1.795TyrSer: 1.795 ± 0.043	1.404TyrThr: 1.404 ± 0.036	1.669TyrVal: 1.669 ± 0.037	0.491TyrTrp: 0.491 ± 0.022	0.872TyrTyr: 0.872 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3377 proteins (1067844 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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