Amino acid dipepetide frequency for Bacillus selenatarsenatis SF-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.569AlaAla: 6.569 ± 0.103	0.499AlaCys: 0.499 ± 0.02	3.697AlaAsp: 3.697 ± 0.06	5.404AlaGlu: 5.404 ± 0.066	3.344AlaPhe: 3.344 ± 0.06	6.079AlaGly: 6.079 ± 0.081	1.221AlaHis: 1.221 ± 0.032	5.763AlaIle: 5.763 ± 0.074	4.672AlaLys: 4.672 ± 0.073	7.028AlaLeu: 7.028 ± 0.079	2.138AlaMet: 2.138 ± 0.042	2.789AlaAsn: 2.789 ± 0.045	2.098AlaPro: 2.098 ± 0.043	2.096AlaGln: 2.096 ± 0.041	2.814AlaArg: 2.814 ± 0.051	4.141AlaSer: 4.141 ± 0.06	3.245AlaThr: 3.245 ± 0.054	5.705AlaVal: 5.705 ± 0.066	0.632AlaTrp: 0.632 ± 0.026	2.197AlaTyr: 2.197 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.371CysAla: 0.371 ± 0.018	0.09CysCys: 0.09 ± 0.008	0.362CysAsp: 0.362 ± 0.019	0.43CysGlu: 0.43 ± 0.021	0.265CysPhe: 0.265 ± 0.015	0.635CysGly: 0.635 ± 0.025	0.181CysHis: 0.181 ± 0.012	0.433CysIle: 0.433 ± 0.019	0.342CysLys: 0.342 ± 0.016	0.531CysLeu: 0.531 ± 0.021	0.155CysMet: 0.155 ± 0.013	0.268CysAsn: 0.268 ± 0.016	0.375CysPro: 0.375 ± 0.018	0.186CysGln: 0.186 ± 0.011	0.249CysArg: 0.249 ± 0.017	0.494CysSer: 0.494 ± 0.021	0.333CysThr: 0.333 ± 0.016	0.354CysVal: 0.354 ± 0.02	0.055CysTrp: 0.055 ± 0.006	0.216CysTyr: 0.216 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.284AspAla: 3.284 ± 0.059	0.372AspCys: 0.372 ± 0.02	2.482AspAsp: 2.482 ± 0.061	4.443AspGlu: 4.443 ± 0.065	2.629AspPhe: 2.629 ± 0.042	3.702AspGly: 3.702 ± 0.067	1.186AspHis: 1.186 ± 0.03	3.955AspIle: 3.955 ± 0.061	3.301AspLys: 3.301 ± 0.055	5.131AspLeu: 5.131 ± 0.063	1.354AspMet: 1.354 ± 0.037	1.822AspAsn: 1.822 ± 0.039	2.106AspPro: 2.106 ± 0.044	2.012AspGln: 2.012 ± 0.043	2.423AspArg: 2.423 ± 0.052	2.855AspSer: 2.855 ± 0.054	2.384AspThr: 2.384 ± 0.046	3.549AspVal: 3.549 ± 0.053	0.643AspTrp: 0.643 ± 0.026	2.128AspTyr: 2.128 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.563GluAla: 5.563 ± 0.08	0.368GluCys: 0.368 ± 0.016	3.971GluAsp: 3.971 ± 0.058	7.231GluGlu: 7.231 ± 0.106	2.983GluPhe: 2.983 ± 0.051	4.662GluGly: 4.662 ± 0.066	1.48GluHis: 1.48 ± 0.033	5.921GluIle: 5.921 ± 0.067	7.113GluLys: 7.113 ± 0.091	7.624GluLeu: 7.624 ± 0.086	2.438GluMet: 2.438 ± 0.045	3.848GluAsn: 3.848 ± 0.057	2.062GluPro: 2.062 ± 0.04	3.164GluGln: 3.164 ± 0.049	3.43GluArg: 3.43 ± 0.055	3.634GluSer: 3.634 ± 0.052	3.976GluThr: 3.976 ± 0.061	5.139GluVal: 5.139 ± 0.067	0.846GluTrp: 0.846 ± 0.027	2.394GluTyr: 2.394 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.34PheAla: 3.34 ± 0.061	0.285PheCys: 0.285 ± 0.013	2.386PheAsp: 2.386 ± 0.045	3.105PheGlu: 3.105 ± 0.048	2.552PhePhe: 2.552 ± 0.063	3.366PheGly: 3.366 ± 0.059	0.987PheHis: 0.987 ± 0.03	3.95PheIle: 3.95 ± 0.069	2.625PheLys: 2.625 ± 0.047	4.766PheLeu: 4.766 ± 0.081	1.259PheMet: 1.259 ± 0.032	2.071PheAsn: 2.071 ± 0.042	1.674PhePro: 1.674 ± 0.039	1.424PheGln: 1.424 ± 0.035	1.541PheArg: 1.541 ± 0.033	3.351PheSer: 3.351 ± 0.05	2.634PheThr: 2.634 ± 0.049	3.074PheVal: 3.074 ± 0.059	0.518PheTrp: 0.518 ± 0.021	1.874PheTyr: 1.874 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	4.965GlyAla: 4.965 ± 0.065	0.592GlyCys: 0.592 ± 0.021	3.38GlyAsp: 3.38 ± 0.051	4.861GlyGlu: 4.861 ± 0.056	3.559GlyPhe: 3.559 ± 0.056	5.0GlyGly: 5.0 ± 0.089	1.422GlyHis: 1.422 ± 0.035	6.131GlyIle: 6.131 ± 0.087	5.268GlyLys: 5.268 ± 0.071	6.881GlyLeu: 6.881 ± 0.081	2.326GlyMet: 2.326 ± 0.051	2.958GlyAsn: 2.958 ± 0.052	1.838GlyPro: 1.838 ± 0.039	2.285GlyGln: 2.285 ± 0.048	2.802GlyArg: 2.802 ± 0.044	4.227GlySer: 4.227 ± 0.064	4.26GlyThr: 4.26 ± 0.062	5.001GlyVal: 5.001 ± 0.062	0.847GlyTrp: 0.847 ± 0.028	2.889GlyTyr: 2.889 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	1.175HisAla: 1.175 ± 0.029	0.188HisCys: 0.188 ± 0.012	1.063HisAsp: 1.063 ± 0.03	1.362HisGlu: 1.362 ± 0.033	1.016HisPhe: 1.016 ± 0.029	1.414HisGly: 1.414 ± 0.033	0.589HisHis: 0.589 ± 0.023	1.363HisIle: 1.363 ± 0.035	1.069HisLys: 1.069 ± 0.032	1.942HisLeu: 1.942 ± 0.037	0.515HisMet: 0.515 ± 0.02	0.768HisAsn: 0.768 ± 0.025	1.044HisPro: 1.044 ± 0.028	0.784HisGln: 0.784 ± 0.027	0.847HisArg: 0.847 ± 0.025	1.221HisSer: 1.221 ± 0.031	0.981HisThr: 0.981 ± 0.031	1.28HisVal: 1.28 ± 0.028	0.203HisTrp: 0.203 ± 0.014	0.806HisTyr: 0.806 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.84IleAla: 5.84 ± 0.077	0.524IleCys: 0.524 ± 0.02	4.27IleAsp: 4.27 ± 0.06	5.733IleGlu: 5.733 ± 0.075	3.391IlePhe: 3.391 ± 0.068	5.91IleGly: 5.91 ± 0.085	1.553IleHis: 1.553 ± 0.035	5.668IleIle: 5.668 ± 0.086	4.736IleLys: 4.736 ± 0.071	7.308IleLeu: 7.308 ± 0.092	1.868IleMet: 1.868 ± 0.039	3.233IleAsn: 3.233 ± 0.046	3.255IlePro: 3.255 ± 0.058	2.603IleGln: 2.603 ± 0.047	2.893IleArg: 2.893 ± 0.054	5.048IleSer: 5.048 ± 0.07	4.082IleThr: 4.082 ± 0.059	5.255IleVal: 5.255 ± 0.075	0.647IleTrp: 0.647 ± 0.025	2.406IleTyr: 2.406 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.94LysAla: 4.94 ± 0.066	0.338LysCys: 0.338 ± 0.018	3.963LysAsp: 3.963 ± 0.059	6.731LysGlu: 6.731 ± 0.095	2.043LysPhe: 2.043 ± 0.042	4.724LysGly: 4.724 ± 0.063	1.281LysHis: 1.281 ± 0.032	4.776LysIle: 4.776 ± 0.063	5.973LysLys: 5.973 ± 0.072	6.177LysLeu: 6.177 ± 0.064	2.392LysMet: 2.392 ± 0.043	3.482LysAsn: 3.482 ± 0.05	2.325LysPro: 2.325 ± 0.045	2.814LysGln: 2.814 ± 0.047	3.12LysArg: 3.12 ± 0.047	3.633LysSer: 3.633 ± 0.049	3.627LysThr: 3.627 ± 0.059	4.887LysVal: 4.887 ± 0.066	0.783LysTrp: 0.783 ± 0.029	2.232LysTyr: 2.232 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	7.675LeuAla: 7.675 ± 0.09	0.499LeuCys: 0.499 ± 0.023	4.915LeuAsp: 4.915 ± 0.071	6.962LeuGlu: 6.962 ± 0.088	5.019LeuPhe: 5.019 ± 0.084	6.613LeuGly: 6.613 ± 0.085	1.786LeuHis: 1.786 ± 0.038	7.182LeuIle: 7.182 ± 0.104	7.076LeuLys: 7.076 ± 0.071	10.043LeuLeu: 10.043 ± 0.132	2.618LeuMet: 2.618 ± 0.047	4.301LeuAsn: 4.301 ± 0.058	3.93LeuPro: 3.93 ± 0.055	3.251LeuGln: 3.251 ± 0.052	3.552LeuArg: 3.552 ± 0.058	6.683LeuSer: 6.683 ± 0.071	5.386LeuThr: 5.386 ± 0.067	6.426LeuVal: 6.426 ± 0.084	0.86LeuTrp: 0.86 ± 0.029	3.121LeuTyr: 3.121 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	2.235MetAla: 2.235 ± 0.041	0.123MetCys: 0.123 ± 0.01	1.584MetAsp: 1.584 ± 0.032	2.245MetGlu: 2.245 ± 0.04	1.15MetPhe: 1.15 ± 0.032	1.901MetGly: 1.901 ± 0.039	0.412MetHis: 0.412 ± 0.017	2.174MetIle: 2.174 ± 0.045	2.51MetLys: 2.51 ± 0.043	2.757MetLeu: 2.757 ± 0.049	0.931MetMet: 0.931 ± 0.028	1.538MetAsn: 1.538 ± 0.035	1.089MetPro: 1.089 ± 0.027	0.862MetGln: 0.862 ± 0.032	1.067MetArg: 1.067 ± 0.031	1.636MetSer: 1.636 ± 0.039	1.654MetThr: 1.654 ± 0.031	1.995MetVal: 1.995 ± 0.043	0.214MetTrp: 0.214 ± 0.013	0.756MetTyr: 0.756 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	2.83AsnAla: 2.83 ± 0.045	0.278AsnCys: 0.278 ± 0.016	2.194AsnAsp: 2.194 ± 0.041	3.655AsnGlu: 3.655 ± 0.056	1.75AsnPhe: 1.75 ± 0.041	3.382AsnGly: 3.382 ± 0.058	0.954AsnHis: 0.954 ± 0.028	3.229AsnIle: 3.229 ± 0.049	2.88AsnLys: 2.88 ± 0.05	3.956AsnLeu: 3.956 ± 0.056	1.251AsnMet: 1.251 ± 0.028	1.959AsnAsn: 1.959 ± 0.045	2.264AsnPro: 2.264 ± 0.041	1.752AsnGln: 1.752 ± 0.04	2.002AsnArg: 2.002 ± 0.04	2.42AsnSer: 2.42 ± 0.043	2.081AsnThr: 2.081 ± 0.046	2.841AsnVal: 2.841 ± 0.045	0.512AsnTrp: 0.512 ± 0.019	1.515AsnTyr: 1.515 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	2.637ProAla: 2.637 ± 0.044	0.193ProCys: 0.193 ± 0.013	2.224ProAsp: 2.224 ± 0.043	3.479ProGlu: 3.479 ± 0.057	1.979ProPhe: 1.979 ± 0.037	2.697ProGly: 2.697 ± 0.054	0.708ProHis: 0.708 ± 0.021	2.618ProIle: 2.618 ± 0.05	2.09ProLys: 2.09 ± 0.042	3.438ProLeu: 3.438 ± 0.055	0.875ProMet: 0.875 ± 0.029	1.523ProAsn: 1.523 ± 0.033	1.008ProPro: 1.008 ± 0.034	1.076ProGln: 1.076 ± 0.033	1.132ProArg: 1.132 ± 0.031	2.143ProSer: 2.143 ± 0.04	1.672ProThr: 1.672 ± 0.037	3.073ProVal: 3.073 ± 0.048	0.376ProTrp: 0.376 ± 0.018	1.383ProTyr: 1.383 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	2.505GlnAla: 2.505 ± 0.053	0.168GlnCys: 0.168 ± 0.011	1.595GlnAsp: 1.595 ± 0.031	2.749GlnGlu: 2.749 ± 0.047	1.571GlnPhe: 1.571 ± 0.033	2.178GlnGly: 2.178 ± 0.044	0.7GlnHis: 0.7 ± 0.027	2.354GlnIle: 2.354 ± 0.044	2.481GlnLys: 2.481 ± 0.044	3.711GlnLeu: 3.711 ± 0.055	1.11GlnMet: 1.11 ± 0.03	1.527GlnAsn: 1.527 ± 0.036	1.192GlnPro: 1.192 ± 0.032	1.621GlnGln: 1.621 ± 0.038	1.365GlnArg: 1.365 ± 0.035	2.043GlnSer: 2.043 ± 0.04	1.777GlnThr: 1.777 ± 0.032	2.233GlnVal: 2.233 ± 0.044	0.389GlnTrp: 0.389 ± 0.017	1.309GlnTyr: 1.309 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	2.356ArgAla: 2.356 ± 0.042	0.222ArgCys: 0.222 ± 0.012	2.071ArgAsp: 2.071 ± 0.044	3.35ArgGlu: 3.35 ± 0.059	1.913ArgPhe: 1.913 ± 0.039	2.416ArgGly: 2.416 ± 0.047	0.751ArgHis: 0.751 ± 0.023	2.997ArgIle: 2.997 ± 0.051	3.363ArgLys: 3.363 ± 0.055	3.868ArgLeu: 3.868 ± 0.056	1.281ArgMet: 1.281 ± 0.031	1.99ArgAsn: 1.99 ± 0.037	1.328ArgPro: 1.328 ± 0.03	1.438ArgGln: 1.438 ± 0.034	1.854ArgArg: 1.854 ± 0.045	2.165ArgSer: 2.165 ± 0.047	2.025ArgThr: 2.025 ± 0.039	2.61ArgVal: 2.61 ± 0.042	0.409ArgTrp: 0.409 ± 0.017	1.483ArgTyr: 1.483 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	4.139SerAla: 4.139 ± 0.061	0.392SerCys: 0.392 ± 0.02	2.846SerAsp: 2.846 ± 0.045	4.174SerGlu: 4.174 ± 0.059	3.335SerPhe: 3.335 ± 0.056	4.674SerGly: 4.674 ± 0.064	1.183SerHis: 1.183 ± 0.031	4.786SerIle: 4.786 ± 0.061	3.747SerLys: 3.747 ± 0.055	6.169SerLeu: 6.169 ± 0.079	1.809SerMet: 1.809 ± 0.035	2.38SerAsn: 2.38 ± 0.044	2.216SerPro: 2.216 ± 0.042	1.964SerGln: 1.964 ± 0.041	2.373SerArg: 2.373 ± 0.043	3.864SerSer: 3.864 ± 0.071	2.946SerThr: 2.946 ± 0.049	4.168SerVal: 4.168 ± 0.051	0.654SerTrp: 0.654 ± 0.025	2.171SerTyr: 2.171 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	4.072ThrAla: 4.072 ± 0.052	0.323ThrCys: 0.323 ± 0.018	2.684ThrAsp: 2.684 ± 0.05	3.676ThrGlu: 3.676 ± 0.063	2.502ThrPhe: 2.502 ± 0.046	4.437ThrGly: 4.437 ± 0.063	0.951ThrHis: 0.951 ± 0.03	4.062ThrIle: 4.062 ± 0.064	3.101ThrLys: 3.101 ± 0.061	5.005ThrLeu: 5.005 ± 0.066	1.37ThrMet: 1.37 ± 0.029	2.147ThrAsn: 2.147 ± 0.042	2.082ThrPro: 2.082 ± 0.035	1.313ThrGln: 1.313 ± 0.031	1.865ThrArg: 1.865 ± 0.042	3.084ThrSer: 3.084 ± 0.045	2.625ThrThr: 2.625 ± 0.05	4.237ThrVal: 4.237 ± 0.063	0.491ThrTrp: 0.491 ± 0.02	1.802ThrTyr: 1.802 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	4.958ValAla: 4.958 ± 0.066	0.509ValCys: 0.509 ± 0.022	3.582ValAsp: 3.582 ± 0.052	4.977ValGlu: 4.977 ± 0.075	3.337ValPhe: 3.337 ± 0.051	4.494ValGly: 4.494 ± 0.065	1.31ValHis: 1.31 ± 0.031	5.617ValIle: 5.617 ± 0.065	4.957ValLys: 4.957 ± 0.055	6.871ValLeu: 6.871 ± 0.079	1.952ValMet: 1.952 ± 0.043	3.061ValAsn: 3.061 ± 0.054	2.745ValPro: 2.745 ± 0.047	2.18ValGln: 2.18 ± 0.042	2.61ValArg: 2.61 ± 0.051	4.539ValSer: 4.539 ± 0.064	3.926ValThr: 3.926 ± 0.06	4.896ValVal: 4.896 ± 0.067	0.654ValTrp: 0.654 ± 0.022	2.303ValTyr: 2.303 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	0.647TrpAla: 0.647 ± 0.025	0.068TrpCys: 0.068 ± 0.007	0.525TrpAsp: 0.525 ± 0.021	0.713TrpGlu: 0.713 ± 0.024	0.542TrpPhe: 0.542 ± 0.02	0.739TrpGly: 0.739 ± 0.024	0.209TrpHis: 0.209 ± 0.012	0.825TrpIle: 0.825 ± 0.027	0.747TrpLys: 0.747 ± 0.022	1.153TrpLeu: 1.153 ± 0.03	0.347TrpMet: 0.347 ± 0.017	0.544TrpAsn: 0.544 ± 0.02	0.279TrpPro: 0.279 ± 0.016	0.337TrpGln: 0.337 ± 0.014	0.403TrpArg: 0.403 ± 0.017	0.573TrpSer: 0.573 ± 0.023	0.495TrpThr: 0.495 ± 0.018	0.653TrpVal: 0.653 ± 0.021	0.161TrpTrp: 0.161 ± 0.012	0.35TrpTyr: 0.35 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.03TyrAla: 2.03 ± 0.041	0.296TyrCys: 0.296 ± 0.017	1.968TyrAsp: 1.968 ± 0.045	2.568TyrGlu: 2.568 ± 0.047	1.902TyrPhe: 1.902 ± 0.041	2.471TyrGly: 2.471 ± 0.04	0.767TyrHis: 0.767 ± 0.026	2.418TyrIle: 2.418 ± 0.044	2.188TyrLys: 2.188 ± 0.043	3.539TyrLeu: 3.539 ± 0.055	0.843TyrMet: 0.843 ± 0.024	1.495TyrAsn: 1.495 ± 0.041	1.413TyrPro: 1.413 ± 0.035	1.416TyrGln: 1.416 ± 0.031	1.547TyrArg: 1.547 ± 0.033	2.236TyrSer: 2.236 ± 0.044	1.72TyrThr: 1.72 ± 0.034	2.105TyrVal: 2.105 ± 0.038	0.414TyrTrp: 0.414 ± 0.019	1.381TyrTyr: 1.381 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4894 proteins (1317473 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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