Amino acid dipepetide frequency for Paeniglutamicibacter gangotriensis Lz1y

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.517AlaAla: 18.517 ± 0.213	0.774AlaCys: 0.774 ± 0.023	6.358AlaAsp: 6.358 ± 0.072	7.732AlaGlu: 7.732 ± 0.098	3.661AlaPhe: 3.661 ± 0.061	11.865AlaGly: 11.865 ± 0.126	2.54AlaHis: 2.54 ± 0.044	5.551AlaIle: 5.551 ± 0.074	4.131AlaLys: 4.131 ± 0.074	13.271AlaLeu: 13.271 ± 0.117	3.2AlaMet: 3.2 ± 0.057	2.877AlaAsn: 2.877 ± 0.05	5.88AlaPro: 5.88 ± 0.076	4.177AlaGln: 4.177 ± 0.061	7.577AlaArg: 7.577 ± 0.096	7.115AlaSer: 7.115 ± 0.08	7.409AlaThr: 7.409 ± 0.079	9.773AlaVal: 9.773 ± 0.106	1.689AlaTrp: 1.689 ± 0.04	2.259AlaTyr: 2.259 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.818CysAla: 0.818 ± 0.026	0.072CysCys: 0.072 ± 0.007	0.342CysAsp: 0.342 ± 0.014	0.351CysGlu: 0.351 ± 0.02	0.224CysPhe: 0.224 ± 0.014	0.745CysGly: 0.745 ± 0.028	0.16CysHis: 0.16 ± 0.012	0.297CysIle: 0.297 ± 0.016	0.127CysLys: 0.127 ± 0.01	0.608CysLeu: 0.608 ± 0.023	0.116CysMet: 0.116 ± 0.009	0.182CysAsn: 0.182 ± 0.011	0.384CysPro: 0.384 ± 0.021	0.176CysGln: 0.176 ± 0.013	0.357CysArg: 0.357 ± 0.017	0.444CysSer: 0.444 ± 0.022	0.461CysThr: 0.461 ± 0.02	0.476CysVal: 0.476 ± 0.023	0.124CysTrp: 0.124 ± 0.01	0.131CysTyr: 0.131 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.037AspAla: 7.037 ± 0.084	0.285AspCys: 0.285 ± 0.017	2.644AspAsp: 2.644 ± 0.059	3.719AspGlu: 3.719 ± 0.062	1.884AspPhe: 1.884 ± 0.042	4.71AspGly: 4.71 ± 0.072	1.135AspHis: 1.135 ± 0.029	2.416AspIle: 2.416 ± 0.048	1.474AspLys: 1.474 ± 0.041	5.516AspLeu: 5.516 ± 0.063	1.068AspMet: 1.068 ± 0.029	0.989AspAsn: 0.989 ± 0.032	3.794AspPro: 3.794 ± 0.054	1.554AspGln: 1.554 ± 0.037	3.047AspArg: 3.047 ± 0.056	3.14AspSer: 3.14 ± 0.056	3.072AspThr: 3.072 ± 0.053	4.025AspVal: 4.025 ± 0.061	0.827AspTrp: 0.827 ± 0.026	1.309AspTyr: 1.309 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	7.407GluAla: 7.407 ± 0.097	0.292GluCys: 0.292 ± 0.014	3.117GluAsp: 3.117 ± 0.06	3.422GluGlu: 3.422 ± 0.055	1.91GluPhe: 1.91 ± 0.039	4.019GluGly: 4.019 ± 0.065	1.761GluHis: 1.761 ± 0.047	2.981GluIle: 2.981 ± 0.052	1.881GluLys: 1.881 ± 0.044	6.944GluLeu: 6.944 ± 0.091	1.176GluMet: 1.176 ± 0.035	1.741GluAsn: 1.741 ± 0.041	2.851GluPro: 2.851 ± 0.05	2.248GluGln: 2.248 ± 0.044	4.071GluArg: 4.071 ± 0.063	3.532GluSer: 3.532 ± 0.052	3.288GluThr: 3.288 ± 0.056	4.408GluVal: 4.408 ± 0.06	0.642GluTrp: 0.642 ± 0.022	1.215GluTyr: 1.215 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.082PheAla: 4.082 ± 0.067	0.254PheCys: 0.254 ± 0.016	2.089PheAsp: 2.089 ± 0.034	1.906PheGlu: 1.906 ± 0.046	1.198PhePhe: 1.198 ± 0.036	3.408PheGly: 3.408 ± 0.063	0.651PheHis: 0.651 ± 0.026	1.545PheIle: 1.545 ± 0.042	0.814PheLys: 0.814 ± 0.024	3.055PheLeu: 3.055 ± 0.052	0.716PheMet: 0.716 ± 0.026	0.954PheAsn: 0.954 ± 0.028	1.468PhePro: 1.468 ± 0.034	0.715PheGln: 0.715 ± 0.025	1.639PheArg: 1.639 ± 0.038	2.249PheSer: 2.249 ± 0.048	2.244PheThr: 2.244 ± 0.041	2.465PheVal: 2.465 ± 0.045	0.483PheTrp: 0.483 ± 0.021	0.694PheTyr: 0.694 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	9.927GlyAla: 9.927 ± 0.113	0.682GlyCys: 0.682 ± 0.024	3.893GlyAsp: 3.893 ± 0.06	4.582GlyGlu: 4.582 ± 0.066	3.433GlyPhe: 3.433 ± 0.058	6.826GlyGly: 6.826 ± 0.105	2.044GlyHis: 2.044 ± 0.039	5.143GlyIle: 5.143 ± 0.076	3.061GlyLys: 3.061 ± 0.053	8.979GlyLeu: 8.979 ± 0.107	2.285GlyMet: 2.285 ± 0.047	2.37GlyAsn: 2.37 ± 0.041	3.889GlyPro: 3.889 ± 0.055	2.951GlyGln: 2.951 ± 0.05	5.209GlyArg: 5.209 ± 0.063	5.86GlySer: 5.86 ± 0.071	6.208GlyThr: 6.208 ± 0.078	6.522GlyVal: 6.522 ± 0.081	1.586GlyTrp: 1.586 ± 0.041	2.273GlyTyr: 2.273 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.422HisAla: 2.422 ± 0.045	0.172HisCys: 0.172 ± 0.013	1.17HisAsp: 1.17 ± 0.034	1.312HisGlu: 1.312 ± 0.034	0.692HisPhe: 0.692 ± 0.026	2.192HisGly: 2.192 ± 0.041	0.693HisHis: 0.693 ± 0.025	0.844HisIle: 0.844 ± 0.028	0.489HisLys: 0.489 ± 0.02	2.314HisLeu: 2.314 ± 0.045	0.429HisMet: 0.429 ± 0.018	0.499HisAsn: 0.499 ± 0.019	1.501HisPro: 1.501 ± 0.037	0.804HisGln: 0.804 ± 0.024	1.671HisArg: 1.671 ± 0.037	1.313HisSer: 1.313 ± 0.034	1.251HisThr: 1.251 ± 0.034	1.65HisVal: 1.65 ± 0.04	0.338HisTrp: 0.338 ± 0.02	0.49HisTyr: 0.49 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	6.103IleAla: 6.103 ± 0.078	0.409IleCys: 0.409 ± 0.018	3.201IleAsp: 3.201 ± 0.052	3.001IleGlu: 3.001 ± 0.046	1.644IlePhe: 1.644 ± 0.041	4.713IleGly: 4.713 ± 0.072	1.022IleHis: 1.022 ± 0.034	2.259IleIle: 2.259 ± 0.049	1.355IleLys: 1.355 ± 0.032	4.204IleLeu: 4.204 ± 0.065	0.975IleMet: 0.975 ± 0.031	1.475IleAsn: 1.475 ± 0.034	2.591IlePro: 2.591 ± 0.045	1.143IleGln: 1.143 ± 0.031	2.67IleArg: 2.67 ± 0.05	3.16IleSer: 3.16 ± 0.055	3.155IleThr: 3.155 ± 0.054	3.793IleVal: 3.793 ± 0.07	0.591IleTrp: 0.591 ± 0.025	0.917IleTyr: 0.917 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	3.527LysAla: 3.527 ± 0.062	0.134LysCys: 0.134 ± 0.01	1.749LysAsp: 1.749 ± 0.043	1.516LysGlu: 1.516 ± 0.036	0.852LysPhe: 0.852 ± 0.024	1.912LysGly: 1.912 ± 0.049	0.753LysHis: 0.753 ± 0.028	1.668LysIle: 1.668 ± 0.039	1.29LysLys: 1.29 ± 0.048	2.977LysLeu: 2.977 ± 0.052	0.794LysMet: 0.794 ± 0.023	1.023LysAsn: 1.023 ± 0.029	1.807LysPro: 1.807 ± 0.051	0.9LysGln: 0.9 ± 0.026	1.911LysArg: 1.911 ± 0.041	1.811LysSer: 1.811 ± 0.044	1.891LysThr: 1.891 ± 0.045	2.428LysVal: 2.428 ± 0.048	0.34LysTrp: 0.34 ± 0.019	0.69LysTyr: 0.69 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.431LeuAla: 14.431 ± 0.14	0.744LeuCys: 0.744 ± 0.027	6.169LeuAsp: 6.169 ± 0.07	6.105LeuGlu: 6.105 ± 0.075	3.036LeuPhe: 3.036 ± 0.058	9.875LeuGly: 9.875 ± 0.109	2.047LeuHis: 2.047 ± 0.041	4.62LeuIle: 4.62 ± 0.066	2.744LeuLys: 2.744 ± 0.05	11.053LeuLeu: 11.053 ± 0.122	2.13LeuMet: 2.13 ± 0.042	2.653LeuAsn: 2.653 ± 0.048	5.51LeuPro: 5.51 ± 0.068	2.6LeuGln: 2.6 ± 0.048	6.854LeuArg: 6.854 ± 0.078	6.28LeuSer: 6.28 ± 0.082	5.672LeuThr: 5.672 ± 0.075	8.747LeuVal: 8.747 ± 0.114	1.247LeuTrp: 1.247 ± 0.032	1.649LeuTyr: 1.649 ± 0.034	0.0LeuXaa: 0.0 ± 0.0
Met	2.806MetAla: 2.806 ± 0.051	0.147MetCys: 0.147 ± 0.01	1.251MetAsp: 1.251 ± 0.031	1.101MetGlu: 1.101 ± 0.034	0.679MetPhe: 0.679 ± 0.025	1.907MetGly: 1.907 ± 0.046	0.464MetHis: 0.464 ± 0.018	1.18MetIle: 1.18 ± 0.033	0.723MetLys: 0.723 ± 0.024	2.489MetLeu: 2.489 ± 0.047	0.496MetMet: 0.496 ± 0.022	0.823MetAsn: 0.823 ± 0.025	1.202MetPro: 1.202 ± 0.03	0.609MetGln: 0.609 ± 0.024	1.507MetArg: 1.507 ± 0.037	1.741MetSer: 1.741 ± 0.033	1.488MetThr: 1.488 ± 0.033	1.884MetVal: 1.884 ± 0.045	0.214MetTrp: 0.214 ± 0.013	0.359MetTyr: 0.359 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.045AsnAla: 3.045 ± 0.054	0.16AsnCys: 0.16 ± 0.012	1.429AsnAsp: 1.429 ± 0.035	1.44AsnGlu: 1.44 ± 0.038	0.825AsnPhe: 0.825 ± 0.021	2.307AsnGly: 2.307 ± 0.048	0.622AsnHis: 0.622 ± 0.022	1.271AsnIle: 1.271 ± 0.035	0.807AsnLys: 0.807 ± 0.026	2.495AsnLeu: 2.495 ± 0.049	0.534AsnMet: 0.534 ± 0.022	0.799AsnAsn: 0.799 ± 0.03	1.973AsnPro: 1.973 ± 0.043	0.88AsnGln: 0.88 ± 0.029	1.574AsnArg: 1.574 ± 0.036	1.48AsnSer: 1.48 ± 0.034	1.653AsnThr: 1.653 ± 0.044	1.847AsnVal: 1.847 ± 0.036	0.41AsnTrp: 0.41 ± 0.017	0.589AsnTyr: 0.589 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	7.003ProAla: 7.003 ± 0.108	0.276ProCys: 0.276 ± 0.016	3.044ProAsp: 3.044 ± 0.058	4.133ProGlu: 4.133 ± 0.059	1.54ProPhe: 1.54 ± 0.038	5.168ProGly: 5.168 ± 0.066	1.143ProHis: 1.143 ± 0.03	1.95ProIle: 1.95 ± 0.04	1.526ProLys: 1.526 ± 0.04	4.738ProLeu: 4.738 ± 0.051	1.226ProMet: 1.226 ± 0.027	1.173ProAsn: 1.173 ± 0.028	1.948ProPro: 1.948 ± 0.042	1.686ProGln: 1.686 ± 0.04	3.027ProArg: 3.027 ± 0.057	3.018ProSer: 3.018 ± 0.053	3.115ProThr: 3.115 ± 0.051	4.602ProVal: 4.602 ± 0.065	0.809ProTrp: 0.809 ± 0.023	1.026ProTyr: 1.026 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.723GlnAla: 3.723 ± 0.061	0.18GlnCys: 0.18 ± 0.012	1.585GlnAsp: 1.585 ± 0.037	1.712GlnGlu: 1.712 ± 0.04	0.866GlnPhe: 0.866 ± 0.029	2.371GlnGly: 2.371 ± 0.047	0.778GlnHis: 0.778 ± 0.026	1.67GlnIle: 1.67 ± 0.035	0.865GlnLys: 0.865 ± 0.028	3.472GlnLeu: 3.472 ± 0.06	0.685GlnMet: 0.685 ± 0.026	0.734GlnAsn: 0.734 ± 0.029	1.392GlnPro: 1.392 ± 0.032	1.266GlnGln: 1.266 ± 0.039	2.437GlnArg: 2.437 ± 0.047	1.591GlnSer: 1.591 ± 0.037	1.511GlnThr: 1.511 ± 0.035	2.55GlnVal: 2.55 ± 0.042	0.508GlnTrp: 0.508 ± 0.02	0.649GlnTyr: 0.649 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	7.109ArgAla: 7.109 ± 0.08	0.41ArgCys: 0.41 ± 0.019	3.249ArgAsp: 3.249 ± 0.053	3.861ArgGlu: 3.861 ± 0.058	2.203ArgPhe: 2.203 ± 0.04	4.715ArgGly: 4.715 ± 0.072	1.522ArgHis: 1.522 ± 0.034	3.407ArgIle: 3.407 ± 0.051	1.99ArgLys: 1.99 ± 0.05	6.302ArgLeu: 6.302 ± 0.093	1.592ArgMet: 1.592 ± 0.036	1.799ArgAsn: 1.799 ± 0.042	2.955ArgPro: 2.955 ± 0.046	1.985ArgGln: 1.985 ± 0.047	4.8ArgArg: 4.8 ± 0.085	3.86ArgSer: 3.86 ± 0.056	3.924ArgThr: 3.924 ± 0.063	4.419ArgVal: 4.419 ± 0.06	1.065ArgTrp: 1.065 ± 0.027	1.428ArgTyr: 1.428 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	7.194SerAla: 7.194 ± 0.09	0.405SerCys: 0.405 ± 0.018	2.805SerAsp: 2.805 ± 0.043	3.239SerGlu: 3.239 ± 0.052	2.113SerPhe: 2.113 ± 0.044	5.84SerGly: 5.84 ± 0.071	1.226SerHis: 1.226 ± 0.025	2.961SerIle: 2.961 ± 0.049	1.865SerLys: 1.865 ± 0.038	6.08SerLeu: 6.08 ± 0.071	1.807SerMet: 1.807 ± 0.039	1.633SerAsn: 1.633 ± 0.034	3.169SerPro: 3.169 ± 0.043	1.708SerGln: 1.708 ± 0.039	3.701SerArg: 3.701 ± 0.056	3.918SerSer: 3.918 ± 0.07	4.171SerThr: 4.171 ± 0.055	4.766SerVal: 4.766 ± 0.056	1.013SerTrp: 1.013 ± 0.028	1.437SerTyr: 1.437 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	7.39ThrAla: 7.39 ± 0.079	0.359ThrCys: 0.359 ± 0.019	3.321ThrAsp: 3.321 ± 0.056	3.627ThrGlu: 3.627 ± 0.05	1.775ThrPhe: 1.775 ± 0.035	6.0ThrGly: 6.0 ± 0.079	1.317ThrHis: 1.317 ± 0.036	2.806ThrIle: 2.806 ± 0.053	1.769ThrLys: 1.769 ± 0.041	6.175ThrLeu: 6.175 ± 0.069	1.353ThrMet: 1.353 ± 0.035	1.48ThrAsn: 1.48 ± 0.035	3.626ThrPro: 3.626 ± 0.057	1.759ThrGln: 1.759 ± 0.039	3.406ThrArg: 3.406 ± 0.058	3.601ThrSer: 3.601 ± 0.057	3.798ThrThr: 3.798 ± 0.064	5.042ThrVal: 5.042 ± 0.072	0.79ThrTrp: 0.79 ± 0.025	1.217ThrTyr: 1.217 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	9.903ValAla: 9.903 ± 0.101	0.544ValCys: 0.544 ± 0.02	4.374ValAsp: 4.374 ± 0.065	4.35ValGlu: 4.35 ± 0.062	2.728ValPhe: 2.728 ± 0.046	6.159ValGly: 6.159 ± 0.075	1.685ValHis: 1.685 ± 0.039	4.253ValIle: 4.253 ± 0.068	2.039ValLys: 2.039 ± 0.051	9.401ValLeu: 9.401 ± 0.099	1.765ValMet: 1.765 ± 0.043	2.002ValAsn: 2.002 ± 0.039	4.518ValPro: 4.518 ± 0.064	2.226ValGln: 2.226 ± 0.046	4.741ValArg: 4.741 ± 0.062	4.824ValSer: 4.824 ± 0.063	4.388ValThr: 4.388 ± 0.064	6.578ValVal: 6.578 ± 0.087	0.843ValTrp: 0.843 ± 0.026	1.315ValTyr: 1.315 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.524TrpAla: 1.524 ± 0.032	0.123TrpCys: 0.123 ± 0.01	0.748TrpAsp: 0.748 ± 0.026	0.706TrpGlu: 0.706 ± 0.025	0.558TrpPhe: 0.558 ± 0.023	1.053TrpGly: 1.053 ± 0.034	0.322TrpHis: 0.322 ± 0.017	0.791TrpIle: 0.791 ± 0.027	0.455TrpLys: 0.455 ± 0.02	1.707TrpLeu: 1.707 ± 0.037	0.367TrpMet: 0.367 ± 0.018	0.444TrpAsn: 0.444 ± 0.02	0.629TrpPro: 0.629 ± 0.023	0.501TrpGln: 0.501 ± 0.025	0.948TrpArg: 0.948 ± 0.031	0.828TrpSer: 0.828 ± 0.022	0.714TrpThr: 0.714 ± 0.028	1.152TrpVal: 1.152 ± 0.034	0.317TrpTrp: 0.317 ± 0.017	0.297TrpTyr: 0.297 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.388TyrAla: 2.388 ± 0.044	0.173TyrCys: 0.173 ± 0.012	1.11TyrAsp: 1.11 ± 0.032	1.091TyrGlu: 1.091 ± 0.032	0.808TyrPhe: 0.808 ± 0.029	1.939TyrGly: 1.939 ± 0.04	0.359TyrHis: 0.359 ± 0.018	0.766TyrIle: 0.766 ± 0.028	0.567TyrLys: 0.567 ± 0.023	2.383TyrLeu: 2.383 ± 0.045	0.36TyrMet: 0.36 ± 0.017	0.487TyrAsn: 0.487 ± 0.02	1.065TyrPro: 1.065 ± 0.031	0.658TyrGln: 0.658 ± 0.025	1.45TyrArg: 1.45 ± 0.035	1.287TyrSer: 1.287 ± 0.032	1.199TyrThr: 1.199 ± 0.032	1.508TyrVal: 1.508 ± 0.037	0.347TyrTrp: 0.347 ± 0.016	0.452TyrTyr: 0.452 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4017 proteins (1241062 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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