Amino acid dipepetide frequency for Eptesicus serotinus papillomavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.697AlaAla: 4.697 ± 0.549
0.427AlaCys: 0.427 ± 0.404
4.27AlaAsp: 4.27 ± 1.735
4.697AlaGlu: 4.697 ± 2.022
2.989AlaPhe: 2.989 ± 0.666
3.416AlaGly: 3.416 ± 1.037
1.281AlaHis: 1.281 ± 0.822
3.416AlaIle: 3.416 ± 0.84
1.281AlaLys: 1.281 ± 0.41
3.843AlaLeu: 3.843 ± 1.283
0.0AlaMet: 0.0 ± 0.0
0.427AlaAsn: 0.427 ± 0.339
4.697AlaPro: 4.697 ± 0.648
2.989AlaGln: 2.989 ± 0.967
6.405AlaArg: 6.405 ± 1.089
2.135AlaSer: 2.135 ± 0.818
2.989AlaThr: 2.989 ± 1.005
4.697AlaVal: 4.697 ± 0.846
0.427AlaTrp: 0.427 ± 0.339
2.135AlaTyr: 2.135 ± 1.06
0.0AlaXaa: 0.0 ± 0.0
Cys
1.708CysAla: 1.708 ± 0.926
0.427CysCys: 0.427 ± 0.339
1.281CysAsp: 1.281 ± 1.026
1.281CysGlu: 1.281 ± 0.795
0.427CysPhe: 0.427 ± 0.471
0.427CysGly: 0.427 ± 0.44
0.854CysHis: 0.854 ± 0.55
0.854CysIle: 0.854 ± 0.634
2.135CysLys: 2.135 ± 0.748
2.135CysLeu: 2.135 ± 1.068
0.427CysMet: 0.427 ± 0.471
0.427CysAsn: 0.427 ± 0.471
2.135CysPro: 2.135 ± 0.796
0.854CysGln: 0.854 ± 0.677
0.427CysArg: 0.427 ± 0.339
2.135CysSer: 2.135 ± 1.331
0.427CysThr: 0.427 ± 0.471
0.427CysVal: 0.427 ± 0.471
0.854CysTrp: 0.854 ± 0.463
1.281CysTyr: 1.281 ± 0.697
0.0CysXaa: 0.0 ± 0.0
Asp
5.124AspAla: 5.124 ± 1.227
2.135AspCys: 2.135 ± 1.43
3.843AspAsp: 3.843 ± 1.625
2.562AspGlu: 2.562 ± 1.182
1.708AspPhe: 1.708 ± 0.562
2.989AspGly: 2.989 ± 0.652
1.708AspHis: 1.708 ± 1.003
4.697AspIle: 4.697 ± 2.175
2.135AspLys: 2.135 ± 0.32
6.405AspLeu: 6.405 ± 1.692
0.854AspMet: 0.854 ± 0.463
2.135AspAsn: 2.135 ± 1.045
5.124AspPro: 5.124 ± 1.259
2.135AspGln: 2.135 ± 1.677
2.562AspArg: 2.562 ± 1.065
5.551AspSer: 5.551 ± 1.384
3.416AspThr: 3.416 ± 1.405
4.697AspVal: 4.697 ± 1.305
1.708AspTrp: 1.708 ± 0.56
1.281AspTyr: 1.281 ± 0.458
0.0AspXaa: 0.0 ± 0.0
Glu
2.989GluAla: 2.989 ± 0.828
1.281GluCys: 1.281 ± 0.801
4.697GluAsp: 4.697 ± 0.961
4.27GluGlu: 4.27 ± 1.223
2.562GluPhe: 2.562 ± 0.846
6.832GluGly: 6.832 ± 1.362
0.854GluHis: 0.854 ± 0.45
2.562GluIle: 2.562 ± 0.924
2.135GluLys: 2.135 ± 1.117
4.697GluLeu: 4.697 ± 0.818
1.281GluMet: 1.281 ± 1.016
1.708GluAsn: 1.708 ± 0.584
2.135GluPro: 2.135 ± 1.04
2.562GluGln: 2.562 ± 0.464
3.843GluArg: 3.843 ± 0.761
3.843GluSer: 3.843 ± 1.327
6.405GluThr: 6.405 ± 2.381
2.135GluVal: 2.135 ± 1.161
1.708GluTrp: 1.708 ± 0.951
1.708GluTyr: 1.708 ± 0.204
0.0GluXaa: 0.0 ± 0.0
Phe
0.854PheAla: 0.854 ± 0.473
0.427PheCys: 0.427 ± 0.471
2.989PheAsp: 2.989 ± 0.969
2.135PheGlu: 2.135 ± 0.351
3.416PhePhe: 3.416 ± 0.906
3.843PheGly: 3.843 ± 1.157
0.427PheHis: 0.427 ± 0.339
0.854PheIle: 0.854 ± 0.463
3.843PheLys: 3.843 ± 1.988
4.27PheLeu: 4.27 ± 1.582
0.854PheMet: 0.854 ± 0.45
0.854PheAsn: 0.854 ± 0.807
2.135PhePro: 2.135 ± 1.078
2.135PheGln: 2.135 ± 1.956
0.854PheArg: 0.854 ± 0.463
2.989PheSer: 2.989 ± 0.84
3.416PheThr: 3.416 ± 1.504
1.281PheVal: 1.281 ± 0.795
2.135PheTrp: 2.135 ± 0.742
2.562PheTyr: 2.562 ± 1.022
0.0PheXaa: 0.0 ± 0.0
Gly
3.416GlyAla: 3.416 ± 0.975
1.708GlyCys: 1.708 ± 0.798
3.843GlyAsp: 3.843 ± 1.16
5.124GlyGlu: 5.124 ± 1.546
0.427GlyPhe: 0.427 ± 0.404
11.956GlyGly: 11.956 ± 7.341
1.281GlyHis: 1.281 ± 0.76
3.843GlyIle: 3.843 ± 1.538
2.562GlyLys: 2.562 ± 0.534
7.259GlyLeu: 7.259 ± 1.315
1.708GlyMet: 1.708 ± 1.36
2.989GlyAsn: 2.989 ± 1.575
2.989GlyPro: 2.989 ± 1.562
1.281GlyGln: 1.281 ± 0.822
8.967GlyArg: 8.967 ± 4.654
5.978GlySer: 5.978 ± 2.642
6.405GlyThr: 6.405 ± 1.411
5.551GlyVal: 5.551 ± 1.483
0.427GlyTrp: 0.427 ± 0.404
1.281GlyTyr: 1.281 ± 0.867
0.0GlyXaa: 0.0 ± 0.0
His
0.854HisAla: 0.854 ± 0.463
0.427HisCys: 0.427 ± 0.339
0.854HisAsp: 0.854 ± 0.394
1.281HisGlu: 1.281 ± 0.801
1.708HisPhe: 1.708 ± 0.78
0.854HisGly: 0.854 ± 0.45
0.427HisHis: 0.427 ± 0.339
0.854HisIle: 0.854 ± 0.473
1.281HisLys: 1.281 ± 0.435
1.281HisLeu: 1.281 ± 0.957
0.0HisMet: 0.0 ± 0.0
0.427HisAsn: 0.427 ± 0.391
1.708HisPro: 1.708 ± 0.9
0.0HisGln: 0.0 ± 0.0
1.281HisArg: 1.281 ± 0.597
2.135HisSer: 2.135 ± 0.82
1.281HisThr: 1.281 ± 0.376
1.708HisVal: 1.708 ± 0.553
0.427HisTrp: 0.427 ± 0.404
1.281HisTyr: 1.281 ± 0.376
0.0HisXaa: 0.0 ± 0.0
Ile
2.135IleAla: 2.135 ± 0.656
1.281IleCys: 1.281 ± 0.617
1.281IleAsp: 1.281 ± 0.558
2.135IleGlu: 2.135 ± 0.784
1.281IlePhe: 1.281 ± 0.867
3.416IleGly: 3.416 ± 1.813
0.427IleHis: 0.427 ± 0.391
1.281IleIle: 1.281 ± 0.708
1.708IleLys: 1.708 ± 0.754
5.978IleLeu: 5.978 ± 1.641
0.854IleMet: 0.854 ± 0.45
1.281IleAsn: 1.281 ± 1.211
3.843IlePro: 3.843 ± 1.727
2.135IleGln: 2.135 ± 0.742
2.562IleArg: 2.562 ± 0.802
2.562IleSer: 2.562 ± 0.627
2.989IleThr: 2.989 ± 0.888
2.989IleVal: 2.989 ± 0.707
0.0IleTrp: 0.0 ± 0.0
1.281IleTyr: 1.281 ± 0.825
0.0IleXaa: 0.0 ± 0.0
Lys
0.854LysAla: 0.854 ± 0.463
0.427LysCys: 0.427 ± 0.442
2.562LysAsp: 2.562 ± 1.056
2.562LysGlu: 2.562 ± 0.934
1.281LysPhe: 1.281 ± 0.663
3.416LysGly: 3.416 ± 1.097
0.427LysHis: 0.427 ± 0.339
1.281LysIle: 1.281 ± 0.822
0.854LysLys: 0.854 ± 0.45
3.843LysLeu: 3.843 ± 2.156
0.427LysMet: 0.427 ± 0.382
3.843LysAsn: 3.843 ± 1.113
1.281LysPro: 1.281 ± 1.016
1.708LysGln: 1.708 ± 0.78
4.697LysArg: 4.697 ± 0.961
2.562LysSer: 2.562 ± 1.648
2.989LysThr: 2.989 ± 1.208
4.27LysVal: 4.27 ± 1.094
0.427LysTrp: 0.427 ± 0.442
1.708LysTyr: 1.708 ± 0.946
0.0LysXaa: 0.0 ± 0.0
Leu
4.27LeuAla: 4.27 ± 1.416
2.135LeuCys: 2.135 ± 1.309
5.551LeuAsp: 5.551 ± 1.625
7.259LeuGlu: 7.259 ± 0.945
5.124LeuPhe: 5.124 ± 1.518
7.259LeuGly: 7.259 ± 1.459
2.135LeuHis: 2.135 ± 1.084
2.135LeuIle: 2.135 ± 0.576
3.843LeuLys: 3.843 ± 2.15
7.259LeuLeu: 7.259 ± 2.102
0.854LeuMet: 0.854 ± 0.511
0.854LeuAsn: 0.854 ± 0.463
4.27LeuPro: 4.27 ± 1.557
5.124LeuGln: 5.124 ± 0.83
5.551LeuArg: 5.551 ± 1.116
6.832LeuSer: 6.832 ± 0.805
4.697LeuThr: 4.697 ± 1.011
7.259LeuVal: 7.259 ± 1.497
0.854LeuTrp: 0.854 ± 0.45
4.27LeuTyr: 4.27 ± 0.959
0.0LeuXaa: 0.0 ± 0.0
Met
0.854MetAla: 0.854 ± 0.807
0.854MetCys: 0.854 ± 0.677
0.854MetAsp: 0.854 ± 0.559
0.854MetGlu: 0.854 ± 0.45
0.427MetPhe: 0.427 ± 0.339
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.427MetIle: 0.427 ± 0.44
0.427MetLys: 0.427 ± 0.442
1.708MetLeu: 1.708 ± 0.539
0.427MetMet: 0.427 ± 0.339
0.427MetAsn: 0.427 ± 0.404
2.135MetPro: 2.135 ± 0.935
0.427MetGln: 0.427 ± 0.442
0.854MetArg: 0.854 ± 0.394
1.708MetSer: 1.708 ± 0.56
0.854MetThr: 0.854 ± 0.45
1.281MetVal: 1.281 ± 0.795
0.0MetTrp: 0.0 ± 0.0
0.427MetTyr: 0.427 ± 0.404
0.0MetXaa: 0.0 ± 0.0
Asn
2.135AsnAla: 2.135 ± 0.694
0.427AsnCys: 0.427 ± 0.339
0.854AsnAsp: 0.854 ± 0.807
1.281AsnGlu: 1.281 ± 0.704
1.281AsnPhe: 1.281 ± 0.998
2.989AsnGly: 2.989 ± 0.951
0.0AsnHis: 0.0 ± 0.0
1.708AsnIle: 1.708 ± 0.798
2.989AsnLys: 2.989 ± 1.246
2.135AsnLeu: 2.135 ± 0.899
0.427AsnMet: 0.427 ± 0.458
0.854AsnAsn: 0.854 ± 0.595
3.843AsnPro: 3.843 ± 1.382
2.562AsnGln: 2.562 ± 1.073
1.708AsnArg: 1.708 ± 0.848
1.708AsnSer: 1.708 ± 1.355
3.843AsnThr: 3.843 ± 1.814
1.281AsnVal: 1.281 ± 0.435
0.427AsnTrp: 0.427 ± 0.339
0.427AsnTyr: 0.427 ± 0.404
0.0AsnXaa: 0.0 ± 0.0
Pro
2.989ProAla: 2.989 ± 1.498
0.854ProCys: 0.854 ± 0.559
5.978ProAsp: 5.978 ± 1.604
4.697ProGlu: 4.697 ± 1.29
3.843ProPhe: 3.843 ± 1.4
5.124ProGly: 5.124 ± 2.857
0.427ProHis: 0.427 ± 0.442
2.135ProIle: 2.135 ± 0.985
3.416ProLys: 3.416 ± 0.938
5.124ProLeu: 5.124 ± 1.728
0.427ProMet: 0.427 ± 0.391
2.135ProAsn: 2.135 ± 0.468
6.832ProPro: 6.832 ± 1.41
2.135ProGln: 2.135 ± 1.009
3.416ProArg: 3.416 ± 1.358
5.124ProSer: 5.124 ± 2.279
5.124ProThr: 5.124 ± 1.562
5.124ProVal: 5.124 ± 2.339
0.0ProTrp: 0.0 ± 0.0
2.135ProTyr: 2.135 ± 1.2
0.0ProXaa: 0.0 ± 0.0
Gln
2.989GlnAla: 2.989 ± 1.216
0.427GlnCys: 0.427 ± 0.339
4.27GlnAsp: 4.27 ± 0.774
3.416GlnGlu: 3.416 ± 2.02
1.708GlnPhe: 1.708 ± 0.926
3.843GlnGly: 3.843 ± 1.045
0.854GlnHis: 0.854 ± 0.45
2.135GlnIle: 2.135 ± 0.821
0.854GlnLys: 0.854 ± 0.45
2.989GlnLeu: 2.989 ± 0.863
1.708GlnMet: 1.708 ± 0.926
4.697GlnAsn: 4.697 ± 2.32
1.708GlnPro: 1.708 ± 0.784
4.27GlnGln: 4.27 ± 0.849
2.135GlnArg: 2.135 ± 0.818
2.989GlnSer: 2.989 ± 1.41
2.135GlnThr: 2.135 ± 0.32
3.843GlnVal: 3.843 ± 1.327
0.427GlnTrp: 0.427 ± 0.339
0.427GlnTyr: 0.427 ± 0.404
0.0GlnXaa: 0.0 ± 0.0
Arg
4.697ArgAla: 4.697 ± 1.178
2.562ArgCys: 2.562 ± 1.135
2.135ArgAsp: 2.135 ± 0.795
2.135ArgGlu: 2.135 ± 0.76
2.562ArgPhe: 2.562 ± 1.156
7.259ArgGly: 7.259 ± 2.835
2.135ArgHis: 2.135 ± 1.266
1.281ArgIle: 1.281 ± 0.837
2.562ArgLys: 2.562 ± 1.0
7.259ArgLeu: 7.259 ± 2.179
0.854ArgMet: 0.854 ± 0.463
0.854ArgAsn: 0.854 ± 0.677
5.124ArgPro: 5.124 ± 2.292
2.989ArgGln: 2.989 ± 1.129
8.113ArgArg: 8.113 ± 2.905
5.124ArgSer: 5.124 ± 2.543
5.124ArgThr: 5.124 ± 1.835
5.551ArgVal: 5.551 ± 1.896
0.854ArgTrp: 0.854 ± 0.884
1.708ArgTyr: 1.708 ± 0.584
0.0ArgXaa: 0.0 ± 0.0
Ser
5.124SerAla: 5.124 ± 1.649
0.427SerCys: 0.427 ± 0.391
2.562SerAsp: 2.562 ± 1.156
4.27SerGlu: 4.27 ± 0.989
1.708SerPhe: 1.708 ± 0.9
4.27SerGly: 4.27 ± 0.984
0.427SerHis: 0.427 ± 0.44
2.562SerIle: 2.562 ± 0.511
2.135SerLys: 2.135 ± 1.143
7.259SerLeu: 7.259 ± 1.897
0.427SerMet: 0.427 ± 0.339
2.562SerAsn: 2.562 ± 0.613
3.416SerPro: 3.416 ± 2.495
3.843SerGln: 3.843 ± 0.89
8.113SerArg: 8.113 ± 3.377
7.686SerSer: 7.686 ± 0.941
6.832SerThr: 6.832 ± 2.486
5.551SerVal: 5.551 ± 0.924
0.0SerTrp: 0.0 ± 0.0
1.708SerTyr: 1.708 ± 0.954
0.0SerXaa: 0.0 ± 0.0
Thr
4.697ThrAla: 4.697 ± 1.079
0.854ThrCys: 0.854 ± 0.559
6.405ThrAsp: 6.405 ± 1.384
4.27ThrGlu: 4.27 ± 1.334
2.989ThrPhe: 2.989 ± 1.171
5.124ThrGly: 5.124 ± 1.217
1.281ThrHis: 1.281 ± 0.435
2.135ThrIle: 2.135 ± 0.942
1.708ThrLys: 1.708 ± 1.615
5.124ThrLeu: 5.124 ± 1.399
2.135ThrMet: 2.135 ± 0.694
2.135ThrAsn: 2.135 ± 0.984
6.405ThrPro: 6.405 ± 1.732
2.989ThrGln: 2.989 ± 1.216
3.416ThrArg: 3.416 ± 1.156
5.124ThrSer: 5.124 ± 1.594
2.562ThrThr: 2.562 ± 1.007
5.978ThrVal: 5.978 ± 1.849
0.427ThrTrp: 0.427 ± 0.44
1.281ThrTyr: 1.281 ± 0.376
0.0ThrXaa: 0.0 ± 0.0
Val
2.989ValAla: 2.989 ± 1.186
2.135ValCys: 2.135 ± 0.899
6.832ValAsp: 6.832 ± 1.026
3.416ValGlu: 3.416 ± 1.895
5.124ValPhe: 5.124 ± 1.041
4.27ValGly: 4.27 ± 1.047
2.989ValHis: 2.989 ± 1.032
4.697ValIle: 4.697 ± 1.808
3.416ValLys: 3.416 ± 1.204
3.843ValLeu: 3.843 ± 1.518
0.0ValMet: 0.0 ± 0.0
3.416ValAsn: 3.416 ± 1.345
5.978ValPro: 5.978 ± 2.207
4.27ValGln: 4.27 ± 1.657
3.416ValArg: 3.416 ± 1.552
2.989ValSer: 2.989 ± 0.675
4.27ValThr: 4.27 ± 1.367
4.27ValVal: 4.27 ± 2.945
0.427ValTrp: 0.427 ± 0.471
2.562ValTyr: 2.562 ± 1.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.854TrpAla: 0.854 ± 0.463
0.854TrpCys: 0.854 ± 0.634
0.427TrpAsp: 0.427 ± 0.391
0.0TrpGlu: 0.0 ± 0.0
0.427TrpPhe: 0.427 ± 0.339
0.427TrpGly: 0.427 ± 0.442
0.854TrpHis: 0.854 ± 0.45
0.854TrpIle: 0.854 ± 0.45
0.854TrpLys: 0.854 ± 0.677
1.708TrpLeu: 1.708 ± 1.003
0.0TrpMet: 0.0 ± 0.0
0.427TrpAsn: 0.427 ± 0.404
0.0TrpPro: 0.0 ± 0.0
0.427TrpGln: 0.427 ± 0.404
0.854TrpArg: 0.854 ± 0.611
0.854TrpSer: 0.854 ± 0.884
0.854TrpThr: 0.854 ± 0.473
1.708TrpVal: 1.708 ± 0.584
0.0TrpTrp: 0.0 ± 0.0
0.427TrpTyr: 0.427 ± 0.339
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.989TyrAla: 2.989 ± 0.863
0.854TyrCys: 0.854 ± 0.578
1.281TyrAsp: 1.281 ± 0.41
2.562TyrGlu: 2.562 ± 0.412
1.281TyrPhe: 1.281 ± 0.76
1.281TyrGly: 1.281 ± 0.609
1.281TyrHis: 1.281 ± 0.458
1.708TyrIle: 1.708 ± 0.674
1.281TyrLys: 1.281 ± 0.704
3.843TyrLeu: 3.843 ± 2.33
0.854TyrMet: 0.854 ± 0.534
0.427TyrAsn: 0.427 ± 0.471
1.281TyrPro: 1.281 ± 0.376
2.989TyrGln: 2.989 ± 0.508
1.708TyrArg: 1.708 ± 0.671
0.854TyrSer: 0.854 ± 0.611
0.427TyrThr: 0.427 ± 0.339
1.708TyrVal: 1.708 ± 0.56
1.281TyrTrp: 1.281 ± 0.41
1.708TyrTyr: 1.708 ± 1.245
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2343 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski