Amino acid dipepetide frequency for Streptacidiphilus jiangxiensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.457AlaAla: 23.457 ± 0.163	1.194AlaCys: 1.194 ± 0.021	8.276AlaAsp: 8.276 ± 0.065	8.743AlaGlu: 8.743 ± 0.077	3.743AlaPhe: 3.743 ± 0.039	13.155AlaGly: 13.155 ± 0.087	3.053AlaHis: 3.053 ± 0.04	3.455AlaIle: 3.455 ± 0.039	2.472AlaLys: 2.472 ± 0.04	15.8AlaLeu: 15.8 ± 0.107	2.503AlaMet: 2.503 ± 0.031	2.179AlaAsn: 2.179 ± 0.037	7.655AlaPro: 7.655 ± 0.074	4.474AlaGln: 4.474 ± 0.04	10.188AlaArg: 10.188 ± 0.075	6.672AlaSer: 6.672 ± 0.063	7.899AlaThr: 7.899 ± 0.066	12.844AlaVal: 12.844 ± 0.083	2.151AlaTrp: 2.151 ± 0.032	2.676AlaTyr: 2.676 ± 0.033	0.0AlaXaa: 0.0 ± 0.0
Cys	1.155CysAla: 1.155 ± 0.019	0.098CysCys: 0.098 ± 0.006	0.476CysAsp: 0.476 ± 0.014	0.351CysGlu: 0.351 ± 0.013	0.245CysPhe: 0.245 ± 0.01	0.978CysGly: 0.978 ± 0.021	0.2CysHis: 0.2 ± 0.009	0.162CysIle: 0.162 ± 0.007	0.09CysLys: 0.09 ± 0.006	0.842CysLeu: 0.842 ± 0.021	0.115CysMet: 0.115 ± 0.006	0.147CysAsn: 0.147 ± 0.007	0.499CysPro: 0.499 ± 0.016	0.193CysGln: 0.193 ± 0.009	0.588CysArg: 0.588 ± 0.016	0.484CysSer: 0.484 ± 0.014	0.529CysThr: 0.529 ± 0.015	0.672CysVal: 0.672 ± 0.017	0.136CysTrp: 0.136 ± 0.006	0.184CysTyr: 0.184 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	7.886AspAla: 7.886 ± 0.055	0.437AspCys: 0.437 ± 0.013	2.956AspAsp: 2.956 ± 0.04	3.484AspGlu: 3.484 ± 0.04	1.504AspPhe: 1.504 ± 0.025	5.971AspGly: 5.971 ± 0.048	1.447AspHis: 1.447 ± 0.024	1.546AspIle: 1.546 ± 0.024	0.806AspLys: 0.806 ± 0.02	6.156AspLeu: 6.156 ± 0.058	0.714AspMet: 0.714 ± 0.015	0.908AspAsn: 0.908 ± 0.018	4.484AspPro: 4.484 ± 0.048	1.742AspGln: 1.742 ± 0.027	4.512AspArg: 4.512 ± 0.042	2.403AspSer: 2.403 ± 0.036	2.91AspThr: 2.91 ± 0.036	4.325AspVal: 4.325 ± 0.037	0.931AspTrp: 0.931 ± 0.02	1.137AspTyr: 1.137 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	7.047GluAla: 7.047 ± 0.07	0.312GluCys: 0.312 ± 0.011	2.455GluAsp: 2.455 ± 0.034	3.181GluGlu: 3.181 ± 0.043	1.347GluPhe: 1.347 ± 0.022	3.748GluGly: 3.748 ± 0.045	1.412GluHis: 1.412 ± 0.025	2.008GluIle: 2.008 ± 0.032	0.962GluLys: 0.962 ± 0.023	6.938GluLeu: 6.938 ± 0.056	0.784GluMet: 0.784 ± 0.017	0.922GluAsn: 0.922 ± 0.019	3.25GluPro: 3.25 ± 0.045	2.439GluGln: 2.439 ± 0.027	5.065GluArg: 5.065 ± 0.054	2.357GluSer: 2.357 ± 0.031	2.586GluThr: 2.586 ± 0.031	4.034GluVal: 4.034 ± 0.045	0.689GluTrp: 0.689 ± 0.015	0.926GluTyr: 0.926 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.923PheAla: 3.923 ± 0.04	0.286PheCys: 0.286 ± 0.009	1.931PheAsp: 1.931 ± 0.031	1.367PheGlu: 1.367 ± 0.024	0.837PhePhe: 0.837 ± 0.02	3.072PheGly: 3.072 ± 0.041	0.657PheHis: 0.657 ± 0.016	0.594PheIle: 0.594 ± 0.017	0.413PheLys: 0.413 ± 0.013	2.578PheLeu: 2.578 ± 0.036	0.389PheMet: 0.389 ± 0.012	0.561PheAsn: 0.561 ± 0.013	1.422PhePro: 1.422 ± 0.026	0.736PheGln: 0.736 ± 0.017	1.804PheArg: 1.804 ± 0.028	1.486PheSer: 1.486 ± 0.025	2.008PheThr: 2.008 ± 0.031	2.241PheVal: 2.241 ± 0.031	0.45PheTrp: 0.45 ± 0.013	0.587PheTyr: 0.587 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	11.643GlyAla: 11.643 ± 0.088	0.866GlyCys: 0.866 ± 0.021	4.656GlyAsp: 4.656 ± 0.043	4.659GlyGlu: 4.659 ± 0.047	2.996GlyPhe: 2.996 ± 0.039	9.002GlyGly: 9.002 ± 0.081	2.358GlyHis: 2.358 ± 0.031	3.184GlyIle: 3.184 ± 0.04	1.86GlyLys: 1.86 ± 0.032	9.99GlyLeu: 9.99 ± 0.079	1.884GlyMet: 1.884 ± 0.027	1.788GlyAsn: 1.788 ± 0.03	5.276GlyPro: 5.276 ± 0.057	2.937GlyGln: 2.937 ± 0.034	7.511GlyArg: 7.511 ± 0.059	5.803GlySer: 5.803 ± 0.054	6.429GlyThr: 6.429 ± 0.065	7.742GlyVal: 7.742 ± 0.053	1.832GlyTrp: 1.832 ± 0.028	2.384GlyTyr: 2.384 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	2.992HisAla: 2.992 ± 0.037	0.215HisCys: 0.215 ± 0.01	1.351HisAsp: 1.351 ± 0.023	1.141HisGlu: 1.141 ± 0.02	0.631HisPhe: 0.631 ± 0.014	2.504HisGly: 2.504 ± 0.032	0.735HisHis: 0.735 ± 0.019	0.57HisIle: 0.57 ± 0.013	0.288HisLys: 0.288 ± 0.01	2.598HisLeu: 2.598 ± 0.036	0.327HisMet: 0.327 ± 0.01	0.377HisAsn: 0.377 ± 0.012	1.902HisPro: 1.902 ± 0.028	0.74HisGln: 0.74 ± 0.017	2.06HisArg: 2.06 ± 0.03	1.026HisSer: 1.026 ± 0.019	1.259HisThr: 1.259 ± 0.022	1.751HisVal: 1.751 ± 0.025	0.41HisTrp: 0.41 ± 0.013	0.49HisTyr: 0.49 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.582IleAla: 4.582 ± 0.042	0.255IleCys: 0.255 ± 0.01	1.973IleAsp: 1.973 ± 0.026	1.649IleGlu: 1.649 ± 0.026	0.673IlePhe: 0.673 ± 0.014	3.445IleGly: 3.445 ± 0.04	0.631IleHis: 0.631 ± 0.014	0.764IleIle: 0.764 ± 0.018	0.573IleLys: 0.573 ± 0.015	2.313IleLeu: 2.313 ± 0.033	0.409IleMet: 0.409 ± 0.011	0.675IleAsn: 0.675 ± 0.016	1.735IlePro: 1.735 ± 0.025	0.746IleGln: 0.746 ± 0.016	2.024IleArg: 2.024 ± 0.029	1.656IleSer: 1.656 ± 0.029	2.048IleThr: 2.048 ± 0.028	2.465IleVal: 2.465 ± 0.034	0.377IleTrp: 0.377 ± 0.01	0.51IleTyr: 0.51 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	2.378LysAla: 2.378 ± 0.04	0.082LysCys: 0.082 ± 0.006	0.926LysAsp: 0.926 ± 0.019	0.815LysGlu: 0.815 ± 0.021	0.351LysPhe: 0.351 ± 0.013	1.371LysGly: 1.371 ± 0.028	0.379LysHis: 0.379 ± 0.013	0.679LysIle: 0.679 ± 0.018	0.474LysLys: 0.474 ± 0.018	1.713LysLeu: 1.713 ± 0.027	0.294LysMet: 0.294 ± 0.01	0.389LysAsn: 0.389 ± 0.014	1.114LysPro: 1.114 ± 0.023	0.596LysGln: 0.596 ± 0.017	1.13LysArg: 1.13 ± 0.021	0.839LysSer: 0.839 ± 0.021	0.942LysThr: 0.942 ± 0.021	1.503LysVal: 1.503 ± 0.026	0.191LysTrp: 0.191 ± 0.008	0.336LysTyr: 0.336 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	16.685LeuAla: 16.685 ± 0.1	0.939LeuCys: 0.939 ± 0.018	6.776LeuAsp: 6.776 ± 0.05	4.457LeuGlu: 4.457 ± 0.046	2.681LeuPhe: 2.681 ± 0.033	10.204LeuGly: 10.204 ± 0.071	2.438LeuHis: 2.438 ± 0.034	3.072LeuIle: 3.072 ± 0.036	1.54LeuLys: 1.54 ± 0.029	12.48LeuLeu: 12.48 ± 0.11	1.595LeuMet: 1.595 ± 0.023	1.696LeuAsn: 1.696 ± 0.028	6.972LeuPro: 6.972 ± 0.056	2.592LeuGln: 2.592 ± 0.031	8.913LeuArg: 8.913 ± 0.073	5.434LeuSer: 5.434 ± 0.043	7.191LeuThr: 7.191 ± 0.051	9.434LeuVal: 9.434 ± 0.075	1.442LeuTrp: 1.442 ± 0.028	1.793LeuTyr: 1.793 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.124MetAla: 2.124 ± 0.029	0.127MetCys: 0.127 ± 0.007	0.841MetAsp: 0.841 ± 0.017	0.657MetGlu: 0.657 ± 0.016	0.409MetPhe: 0.409 ± 0.013	1.242MetGly: 1.242 ± 0.024	0.349MetHis: 0.349 ± 0.011	0.607MetIle: 0.607 ± 0.015	0.332MetLys: 0.332 ± 0.011	1.698MetLeu: 1.698 ± 0.023	0.279MetMet: 0.279 ± 0.011	0.422MetAsn: 0.422 ± 0.012	1.076MetPro: 1.076 ± 0.023	0.449MetGln: 0.449 ± 0.013	1.304MetArg: 1.304 ± 0.023	1.293MetSer: 1.293 ± 0.022	1.525MetThr: 1.525 ± 0.026	1.253MetVal: 1.253 ± 0.021	0.188MetTrp: 0.188 ± 0.009	0.278MetTyr: 0.278 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.345AsnAla: 2.345 ± 0.033	0.168AsnCys: 0.168 ± 0.007	0.905AsnAsp: 0.905 ± 0.017	0.75AsnGlu: 0.75 ± 0.017	0.493AsnPhe: 0.493 ± 0.015	2.083AsnGly: 2.083 ± 0.037	0.418AsnHis: 0.418 ± 0.013	0.638AsnIle: 0.638 ± 0.018	0.317AsnLys: 0.317 ± 0.011	1.781AsnLeu: 1.781 ± 0.028	0.277AsnMet: 0.277 ± 0.011	0.451AsnAsn: 0.451 ± 0.016	1.498AsnPro: 1.498 ± 0.027	0.586AsnGln: 0.586 ± 0.017	1.192AsnArg: 1.192 ± 0.023	0.991AsnSer: 0.991 ± 0.022	1.161AsnThr: 1.161 ± 0.026	1.357AsnVal: 1.357 ± 0.024	0.305AsnTrp: 0.305 ± 0.01	0.427AsnTyr: 0.427 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	9.168ProAla: 9.168 ± 0.082	0.363ProCys: 0.363 ± 0.012	4.341ProAsp: 4.341 ± 0.045	3.994ProGlu: 3.994 ± 0.052	1.624ProPhe: 1.624 ± 0.025	6.787ProGly: 6.787 ± 0.061	1.359ProHis: 1.359 ± 0.021	1.401ProIle: 1.401 ± 0.025	0.977ProLys: 0.977 ± 0.02	5.69ProLeu: 5.69 ± 0.051	0.98ProMet: 0.98 ± 0.019	1.079ProAsn: 1.079 ± 0.024	3.396ProPro: 3.396 ± 0.055	2.103ProGln: 2.103 ± 0.03	3.868ProArg: 3.868 ± 0.039	3.473ProSer: 3.473 ± 0.039	3.866ProThr: 3.866 ± 0.049	5.539ProVal: 5.539 ± 0.055	0.935ProTrp: 0.935 ± 0.021	1.275ProTyr: 1.275 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	4.478GlnAla: 4.478 ± 0.044	0.188GlnCys: 0.188 ± 0.008	1.429GlnAsp: 1.429 ± 0.024	1.495GlnGlu: 1.495 ± 0.027	0.742GlnPhe: 0.742 ± 0.018	2.493GlnGly: 2.493 ± 0.031	0.731GlnHis: 0.731 ± 0.017	1.145GlnIle: 1.145 ± 0.019	0.469GlnLys: 0.469 ± 0.014	3.534GlnLeu: 3.534 ± 0.034	0.498GlnMet: 0.498 ± 0.014	0.623GlnAsn: 0.623 ± 0.018	2.013GlnPro: 2.013 ± 0.03	1.573GlnGln: 1.573 ± 0.033	2.475GlnArg: 2.475 ± 0.032	1.507GlnSer: 1.507 ± 0.025	1.554GlnThr: 1.554 ± 0.023	2.771GlnVal: 2.771 ± 0.035	0.532GlnTrp: 0.532 ± 0.014	0.66GlnTyr: 0.66 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	10.103ArgAla: 10.103 ± 0.078	0.573ArgCys: 0.573 ± 0.015	3.767ArgAsp: 3.767 ± 0.04	4.41ArgGlu: 4.41 ± 0.049	2.239ArgPhe: 2.239 ± 0.031	5.446ArgGly: 5.446 ± 0.047	2.076ArgHis: 2.076 ± 0.031	2.968ArgIle: 2.968 ± 0.033	1.209ArgLys: 1.209 ± 0.025	8.947ArgLeu: 8.947 ± 0.079	1.639ArgMet: 1.639 ± 0.025	1.239ArgAsn: 1.239 ± 0.022	4.867ArgPro: 4.867 ± 0.047	2.32ArgGln: 2.32 ± 0.032	7.558ArgArg: 7.558 ± 0.079	3.997ArgSer: 3.997 ± 0.042	4.877ArgThr: 4.877 ± 0.044	5.685ArgVal: 5.685 ± 0.052	1.369ArgTrp: 1.369 ± 0.024	1.709ArgTyr: 1.709 ± 0.028	0.0ArgXaa: 0.0 ± 0.0
Ser	7.385SerAla: 7.385 ± 0.066	0.472SerCys: 0.472 ± 0.014	2.506SerAsp: 2.506 ± 0.032	2.189SerGlu: 2.189 ± 0.032	1.623SerPhe: 1.623 ± 0.024	6.317SerGly: 6.317 ± 0.062	1.032SerHis: 1.032 ± 0.017	1.455SerIle: 1.455 ± 0.025	0.819SerLys: 0.819 ± 0.02	5.074SerLeu: 5.074 ± 0.045	1.019SerMet: 1.019 ± 0.018	0.966SerAsn: 0.966 ± 0.021	3.317SerPro: 3.317 ± 0.041	1.384SerGln: 1.384 ± 0.022	3.573SerArg: 3.573 ± 0.037	3.278SerSer: 3.278 ± 0.046	3.408SerThr: 3.408 ± 0.047	4.491SerVal: 4.491 ± 0.043	0.994SerTrp: 0.994 ± 0.022	1.209SerTyr: 1.209 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	9.264ThrAla: 9.264 ± 0.067	0.449ThrCys: 0.449 ± 0.014	3.543ThrAsp: 3.543 ± 0.041	2.984ThrGlu: 2.984 ± 0.038	1.622ThrPhe: 1.622 ± 0.026	6.815ThrGly: 6.815 ± 0.063	1.229ThrHis: 1.229 ± 0.025	1.644ThrIle: 1.644 ± 0.029	0.944ThrLys: 0.944 ± 0.021	6.073ThrLeu: 6.073 ± 0.049	0.932ThrMet: 0.932 ± 0.017	1.121ThrAsn: 1.121 ± 0.026	4.467ThrPro: 4.467 ± 0.05	1.58ThrGln: 1.58 ± 0.027	3.755ThrArg: 3.755 ± 0.039	3.354ThrSer: 3.354 ± 0.047	4.209ThrThr: 4.209 ± 0.05	6.209ThrVal: 6.209 ± 0.063	0.952ThrTrp: 0.952 ± 0.022	1.194ThrTyr: 1.194 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	11.522ValAla: 11.522 ± 0.072	0.758ValCys: 0.758 ± 0.015	5.046ValAsp: 5.046 ± 0.047	4.469ValGlu: 4.469 ± 0.045	2.409ValPhe: 2.409 ± 0.031	7.018ValGly: 7.018 ± 0.061	2.019ValHis: 2.019 ± 0.027	2.601ValIle: 2.601 ± 0.032	1.384ValLys: 1.384 ± 0.025	9.964ValLeu: 9.964 ± 0.07	1.284ValMet: 1.284 ± 0.021	1.729ValAsn: 1.729 ± 0.023	5.301ValPro: 5.301 ± 0.05	2.297ValGln: 2.297 ± 0.029	6.417ValArg: 6.417 ± 0.056	4.383ValSer: 4.383 ± 0.042	5.598ValThr: 5.598 ± 0.052	8.292ValVal: 8.292 ± 0.066	1.158ValTrp: 1.158 ± 0.021	1.536ValTyr: 1.536 ± 0.026	0.0ValXaa: 0.0 ± 0.0
Trp	1.738TrpAla: 1.738 ± 0.031	0.169TrpCys: 0.169 ± 0.007	0.787TrpAsp: 0.787 ± 0.016	0.692TrpGlu: 0.692 ± 0.017	0.549TrpPhe: 0.549 ± 0.016	1.065TrpGly: 1.065 ± 0.021	0.412TrpHis: 0.412 ± 0.013	0.582TrpIle: 0.582 ± 0.016	0.276TrpLys: 0.276 ± 0.01	1.935TrpLeu: 1.935 ± 0.029	0.294TrpMet: 0.294 ± 0.011	0.439TrpAsn: 0.439 ± 0.015	0.835TrpPro: 0.835 ± 0.016	0.69TrpGln: 0.69 ± 0.017	1.304TrpArg: 1.304 ± 0.021	1.082TrpSer: 1.082 ± 0.022	1.152TrpThr: 1.152 ± 0.021	1.026TrpVal: 1.026 ± 0.021	0.361TrpTrp: 0.361 ± 0.013	0.38TrpTyr: 0.38 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.714TyrAla: 2.714 ± 0.035	0.194TyrCys: 0.194 ± 0.008	1.318TyrAsp: 1.318 ± 0.025	0.973TyrGlu: 0.973 ± 0.018	0.624TyrPhe: 0.624 ± 0.017	2.083TyrGly: 2.083 ± 0.031	0.431TyrHis: 0.431 ± 0.013	0.427TyrIle: 0.427 ± 0.014	0.295TyrLys: 0.295 ± 0.012	2.231TyrLeu: 2.231 ± 0.029	0.235TyrMet: 0.235 ± 0.01	0.433TyrAsn: 0.433 ± 0.014	1.142TyrPro: 1.142 ± 0.022	0.732TyrGln: 0.732 ± 0.019	1.759TyrArg: 1.759 ± 0.028	0.993TyrSer: 0.993 ± 0.022	1.189TyrThr: 1.189 ± 0.024	1.551TyrVal: 1.551 ± 0.025	0.366TyrTrp: 0.366 ± 0.013	0.478TyrTyr: 0.478 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 8703 proteins (2823145 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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