Amino acid dipepetide frequency for Duganella ginsengisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.55AlaAla: 19.55 ± 0.207	1.288AlaCys: 1.288 ± 0.028	6.816AlaAsp: 6.816 ± 0.071	6.181AlaGlu: 6.181 ± 0.08	3.852AlaPhe: 3.852 ± 0.047	11.087AlaGly: 11.087 ± 0.107	2.557AlaHis: 2.557 ± 0.038	5.851AlaIle: 5.851 ± 0.066	4.269AlaLys: 4.269 ± 0.066	14.503AlaLeu: 14.503 ± 0.169	3.743AlaMet: 3.743 ± 0.051	3.655AlaAsn: 3.655 ± 0.05	6.37AlaPro: 6.37 ± 0.08	5.994AlaGln: 5.994 ± 0.078	7.559AlaArg: 7.559 ± 0.078	7.116AlaSer: 7.116 ± 0.08	6.204AlaThr: 6.204 ± 0.071	8.795AlaVal: 8.795 ± 0.081	1.741AlaTrp: 1.741 ± 0.032	3.063AlaTyr: 3.063 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	1.216CysAla: 1.216 ± 0.029	0.134CysCys: 0.134 ± 0.009	0.512CysAsp: 0.512 ± 0.016	0.402CysGlu: 0.402 ± 0.016	0.282CysPhe: 0.282 ± 0.011	0.915CysGly: 0.915 ± 0.027	0.254CysHis: 0.254 ± 0.011	0.402CysIle: 0.402 ± 0.015	0.281CysLys: 0.281 ± 0.011	0.767CysLeu: 0.767 ± 0.019	0.202CysMet: 0.202 ± 0.008	0.253CysAsn: 0.253 ± 0.011	0.39CysPro: 0.39 ± 0.016	0.253CysGln: 0.253 ± 0.011	0.527CysArg: 0.527 ± 0.015	0.507CysSer: 0.507 ± 0.016	0.503CysThr: 0.503 ± 0.017	0.664CysVal: 0.664 ± 0.019	0.129CysTrp: 0.129 ± 0.008	0.235CysTyr: 0.235 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.061AspAla: 7.061 ± 0.064	0.455AspCys: 0.455 ± 0.015	2.96AspAsp: 2.96 ± 0.041	2.914AspGlu: 2.914 ± 0.047	1.998AspPhe: 1.998 ± 0.034	5.109AspGly: 5.109 ± 0.08	1.088AspHis: 1.088 ± 0.022	2.84AspIle: 2.84 ± 0.04	2.175AspLys: 2.175 ± 0.04	4.892AspLeu: 4.892 ± 0.055	1.464AspMet: 1.464 ± 0.026	1.626AspAsn: 1.626 ± 0.03	2.644AspPro: 2.644 ± 0.039	1.923AspGln: 1.923 ± 0.049	2.837AspArg: 2.837 ± 0.041	2.656AspSer: 2.656 ± 0.036	2.896AspThr: 2.896 ± 0.051	4.191AspVal: 4.191 ± 0.051	0.824AspTrp: 0.824 ± 0.021	1.608AspTyr: 1.608 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	5.983GluAla: 5.983 ± 0.075	0.394GluCys: 0.394 ± 0.014	2.033GluAsp: 2.033 ± 0.033	2.632GluGlu: 2.632 ± 0.048	1.771GluPhe: 1.771 ± 0.037	3.351GluGly: 3.351 ± 0.054	1.283GluHis: 1.283 ± 0.028	2.545GluIle: 2.545 ± 0.041	2.11GluLys: 2.11 ± 0.043	5.69GluLeu: 5.69 ± 0.066	1.285GluMet: 1.285 ± 0.026	1.441GluAsn: 1.441 ± 0.027	2.129GluPro: 2.129 ± 0.038	3.029GluGln: 3.029 ± 0.049	3.957GluArg: 3.957 ± 0.057	2.299GluSer: 2.299 ± 0.038	2.568GluThr: 2.568 ± 0.044	3.279GluVal: 3.279 ± 0.046	0.67GluTrp: 0.67 ± 0.017	1.205GluTyr: 1.205 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.031PheAla: 4.031 ± 0.05	0.351PheCys: 0.351 ± 0.014	2.496PheAsp: 2.496 ± 0.032	1.732PheGlu: 1.732 ± 0.032	1.252PhePhe: 1.252 ± 0.026	3.111PheGly: 3.111 ± 0.042	0.754PheHis: 0.754 ± 0.021	1.626PheIle: 1.626 ± 0.031	1.274PheLys: 1.274 ± 0.027	2.759PheLeu: 2.759 ± 0.043	0.842PheMet: 0.842 ± 0.02	1.345PheAsn: 1.345 ± 0.026	1.402PhePro: 1.402 ± 0.031	1.12PheGln: 1.12 ± 0.024	1.806PheArg: 1.806 ± 0.033	2.238PheSer: 2.238 ± 0.033	2.155PheThr: 2.155 ± 0.037	2.375PheVal: 2.375 ± 0.037	0.414PheTrp: 0.414 ± 0.014	0.955PheTyr: 0.955 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	9.631GlyAla: 9.631 ± 0.098	0.77GlyCys: 0.77 ± 0.019	4.099GlyAsp: 4.099 ± 0.05	3.912GlyGlu: 3.912 ± 0.055	2.995GlyPhe: 2.995 ± 0.039	6.915GlyGly: 6.915 ± 0.092	1.873GlyHis: 1.873 ± 0.033	4.085GlyIle: 4.085 ± 0.043	4.028GlyLys: 4.028 ± 0.057	7.805GlyLeu: 7.805 ± 0.083	2.639GlyMet: 2.639 ± 0.04	2.897GlyAsn: 2.897 ± 0.056	2.716GlyPro: 2.716 ± 0.042	3.223GlyGln: 3.223 ± 0.048	4.638GlyArg: 4.638 ± 0.05	4.719GlySer: 4.719 ± 0.078	4.525GlyThr: 4.525 ± 0.077	6.189GlyVal: 6.189 ± 0.051	1.304GlyTrp: 1.304 ± 0.028	2.558GlyTyr: 2.558 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	2.889HisAla: 2.889 ± 0.04	0.258HisCys: 0.258 ± 0.012	1.224HisAsp: 1.224 ± 0.024	1.132HisGlu: 1.132 ± 0.023	0.897HisPhe: 0.897 ± 0.022	2.148HisGly: 2.148 ± 0.037	0.632HisHis: 0.632 ± 0.021	1.064HisIle: 1.064 ± 0.022	0.652HisLys: 0.652 ± 0.017	2.011HisLeu: 2.011 ± 0.033	0.586HisMet: 0.586 ± 0.017	0.599HisAsn: 0.599 ± 0.016	1.294HisPro: 1.294 ± 0.026	0.76HisGln: 0.76 ± 0.019	1.207HisArg: 1.207 ± 0.027	1.104HisSer: 1.104 ± 0.025	1.168HisThr: 1.168 ± 0.024	1.653HisVal: 1.653 ± 0.032	0.356HisTrp: 0.356 ± 0.013	0.715HisTyr: 0.715 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.544IleAla: 6.544 ± 0.069	0.434IleCys: 0.434 ± 0.014	3.183IleAsp: 3.183 ± 0.045	2.75IleGlu: 2.75 ± 0.045	1.338IlePhe: 1.338 ± 0.029	4.125IleGly: 4.125 ± 0.053	0.909IleHis: 0.909 ± 0.021	1.903IleIle: 1.903 ± 0.036	1.715IleLys: 1.715 ± 0.029	3.535IleLeu: 3.535 ± 0.05	0.928IleMet: 0.928 ± 0.022	1.718IleAsn: 1.718 ± 0.036	2.114IlePro: 2.114 ± 0.035	1.256IleGln: 1.256 ± 0.024	2.556IleArg: 2.556 ± 0.035	2.77IleSer: 2.77 ± 0.048	2.823IleThr: 2.823 ± 0.048	3.505IleVal: 3.505 ± 0.043	0.431IleTrp: 0.431 ± 0.015	1.067IleTyr: 1.067 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	4.419LysAla: 4.419 ± 0.067	0.185LysCys: 0.185 ± 0.01	1.877LysAsp: 1.877 ± 0.037	1.919LysGlu: 1.919 ± 0.038	1.136LysPhe: 1.136 ± 0.028	2.609LysGly: 2.609 ± 0.042	0.757LysHis: 0.757 ± 0.018	1.755LysIle: 1.755 ± 0.034	1.642LysLys: 1.642 ± 0.04	4.095LysLeu: 4.095 ± 0.056	1.035LysMet: 1.035 ± 0.024	1.224LysAsn: 1.224 ± 0.027	2.16LysPro: 2.16 ± 0.037	1.566LysGln: 1.566 ± 0.028	2.212LysArg: 2.212 ± 0.036	1.956LysSer: 1.956 ± 0.035	2.113LysThr: 2.113 ± 0.038	2.841LysVal: 2.841 ± 0.044	0.41LysTrp: 0.41 ± 0.015	0.848LysTyr: 0.848 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	14.933LeuAla: 14.933 ± 0.128	0.968LeuCys: 0.968 ± 0.024	5.771LeuAsp: 5.771 ± 0.061	5.006LeuGlu: 5.006 ± 0.061	3.293LeuPhe: 3.293 ± 0.047	7.532LeuGly: 7.532 ± 0.063	2.309LeuHis: 2.309 ± 0.038	3.866LeuIle: 3.866 ± 0.049	3.881LeuLys: 3.881 ± 0.053	10.511LeuLeu: 10.511 ± 0.11	2.413LeuMet: 2.413 ± 0.037	3.173LeuAsn: 3.173 ± 0.051	5.897LeuPro: 5.897 ± 0.056	4.382LeuGln: 4.382 ± 0.064	6.932LeuArg: 6.932 ± 0.076	6.29LeuSer: 6.29 ± 0.083	5.508LeuThr: 5.508 ± 0.111	6.855LeuVal: 6.855 ± 0.068	1.149LeuTrp: 1.149 ± 0.025	2.386LeuTyr: 2.386 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	3.51MetAla: 3.51 ± 0.048	0.172MetCys: 0.172 ± 0.009	1.284MetAsp: 1.284 ± 0.024	1.261MetGlu: 1.261 ± 0.024	0.761MetPhe: 0.761 ± 0.021	1.837MetGly: 1.837 ± 0.034	0.582MetHis: 0.582 ± 0.017	0.97MetIle: 0.97 ± 0.022	1.131MetLys: 1.131 ± 0.023	2.959MetLeu: 2.959 ± 0.042	0.716MetMet: 0.716 ± 0.02	0.958MetAsn: 0.958 ± 0.019	1.548MetPro: 1.548 ± 0.03	1.283MetGln: 1.283 ± 0.025	1.751MetArg: 1.751 ± 0.03	1.494MetSer: 1.494 ± 0.027	1.627MetThr: 1.627 ± 0.028	1.795MetVal: 1.795 ± 0.034	0.243MetTrp: 0.243 ± 0.012	0.493MetTyr: 0.493 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.861AsnAla: 3.861 ± 0.054	0.276AsnCys: 0.276 ± 0.012	1.645AsnAsp: 1.645 ± 0.03	1.343AsnGlu: 1.343 ± 0.024	1.122AsnPhe: 1.122 ± 0.022	3.01AsnGly: 3.01 ± 0.049	0.598AsnHis: 0.598 ± 0.018	1.548AsnIle: 1.548 ± 0.034	1.104AsnLys: 1.104 ± 0.025	2.973AsnLeu: 2.973 ± 0.043	0.771AsnMet: 0.771 ± 0.022	1.115AsnAsn: 1.115 ± 0.029	1.775AsnPro: 1.775 ± 0.033	1.095AsnGln: 1.095 ± 0.025	1.847AsnArg: 1.847 ± 0.031	1.692AsnSer: 1.692 ± 0.039	1.862AsnThr: 1.862 ± 0.039	2.46AsnVal: 2.46 ± 0.044	0.481AsnTrp: 0.481 ± 0.017	0.916AsnTyr: 0.916 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.977ProAla: 6.977 ± 0.079	0.33ProCys: 0.33 ± 0.015	3.292ProAsp: 3.292 ± 0.043	2.877ProGlu: 2.877 ± 0.046	1.655ProPhe: 1.655 ± 0.027	4.347ProGly: 4.347 ± 0.058	1.092ProHis: 1.092 ± 0.022	1.708ProIle: 1.708 ± 0.03	1.472ProLys: 1.472 ± 0.028	4.982ProLeu: 4.982 ± 0.052	1.19ProMet: 1.19 ± 0.026	1.42ProAsn: 1.42 ± 0.028	2.545ProPro: 2.545 ± 0.051	2.172ProGln: 2.172 ± 0.037	2.422ProArg: 2.422 ± 0.038	2.578ProSer: 2.578 ± 0.03	2.122ProThr: 2.122 ± 0.04	4.141ProVal: 4.141 ± 0.044	0.599ProTrp: 0.599 ± 0.019	1.238ProTyr: 1.238 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	5.876GlnAla: 5.876 ± 0.066	0.307GlnCys: 0.307 ± 0.013	1.794GlnAsp: 1.794 ± 0.03	1.849GlnGlu: 1.849 ± 0.035	1.513GlnPhe: 1.513 ± 0.029	3.074GlnGly: 3.074 ± 0.04	1.061GlnHis: 1.061 ± 0.025	1.873GlnIle: 1.873 ± 0.061	1.263GlnLys: 1.263 ± 0.026	4.723GlnLeu: 4.723 ± 0.076	1.125GlnMet: 1.125 ± 0.021	1.047GlnAsn: 1.047 ± 0.024	2.356GlnPro: 2.356 ± 0.039	2.52GlnGln: 2.52 ± 0.05	3.361GlnArg: 3.361 ± 0.051	2.045GlnSer: 2.045 ± 0.036	1.988GlnThr: 1.988 ± 0.032	3.167GlnVal: 3.167 ± 0.06	0.622GlnTrp: 0.622 ± 0.018	1.044GlnTyr: 1.044 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	6.793ArgAla: 6.793 ± 0.064	0.557ArgCys: 0.557 ± 0.018	3.439ArgAsp: 3.439 ± 0.047	3.394ArgGlu: 3.394 ± 0.051	2.367ArgPhe: 2.367 ± 0.037	3.841ArgGly: 3.841 ± 0.053	1.781ArgHis: 1.781 ± 0.033	3.394ArgIle: 3.394 ± 0.041	2.266ArgLys: 2.266 ± 0.035	6.7ArgLeu: 6.7 ± 0.072	1.86ArgMet: 1.86 ± 0.032	2.062ArgAsn: 2.062 ± 0.032	2.62ArgPro: 2.62 ± 0.041	2.916ArgGln: 2.916 ± 0.05	4.192ArgArg: 4.192 ± 0.064	3.123ArgSer: 3.123 ± 0.045	3.218ArgThr: 3.218 ± 0.039	4.05ArgVal: 4.05 ± 0.048	0.939ArgTrp: 0.939 ± 0.024	2.04ArgTyr: 2.04 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	6.831SerAla: 6.831 ± 0.073	0.44SerCys: 0.44 ± 0.015	2.896SerAsp: 2.896 ± 0.048	2.466SerGlu: 2.466 ± 0.035	1.986SerPhe: 1.986 ± 0.035	5.554SerGly: 5.554 ± 0.089	1.279SerHis: 1.279 ± 0.024	2.535SerIle: 2.535 ± 0.04	1.899SerLys: 1.899 ± 0.038	5.73SerLeu: 5.73 ± 0.065	1.412SerMet: 1.412 ± 0.028	1.729SerAsn: 1.729 ± 0.033	2.529SerPro: 2.529 ± 0.037	2.076SerGln: 2.076 ± 0.037	3.239SerArg: 3.239 ± 0.041	3.415SerSer: 3.415 ± 0.079	3.23SerThr: 3.23 ± 0.081	4.139SerVal: 4.139 ± 0.078	0.734SerTrp: 0.734 ± 0.021	1.594SerTyr: 1.594 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	6.636ThrAla: 6.636 ± 0.097	0.4ThrCys: 0.4 ± 0.014	2.824ThrAsp: 2.824 ± 0.059	2.358ThrGlu: 2.358 ± 0.036	1.795ThrPhe: 1.795 ± 0.034	5.004ThrGly: 5.004 ± 0.072	1.063ThrHis: 1.063 ± 0.026	2.6ThrIle: 2.6 ± 0.048	1.443ThrLys: 1.443 ± 0.031	6.097ThrLeu: 6.097 ± 0.071	1.283ThrMet: 1.283 ± 0.025	1.537ThrAsn: 1.537 ± 0.037	3.287ThrPro: 3.287 ± 0.045	2.078ThrGln: 2.078 ± 0.051	2.863ThrArg: 2.863 ± 0.041	3.161ThrSer: 3.161 ± 0.08	3.063ThrThr: 3.063 ± 0.095	4.763ThrVal: 4.763 ± 0.077	0.677ThrTrp: 0.677 ± 0.021	1.457ThrTyr: 1.457 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	9.367ValAla: 9.367 ± 0.091	0.677ValCys: 0.677 ± 0.017	3.782ValAsp: 3.782 ± 0.049	3.81ValGlu: 3.81 ± 0.048	2.44ValPhe: 2.44 ± 0.038	4.881ValGly: 4.881 ± 0.054	1.547ValHis: 1.547 ± 0.029	3.414ValIle: 3.414 ± 0.043	2.751ValLys: 2.751 ± 0.046	7.923ValLeu: 7.923 ± 0.065	1.907ValMet: 1.907 ± 0.03	2.386ValAsn: 2.386 ± 0.042	3.558ValPro: 3.558 ± 0.042	3.041ValGln: 3.041 ± 0.04	4.695ValArg: 4.695 ± 0.055	4.226ValSer: 4.226 ± 0.061	4.523ValThr: 4.523 ± 0.076	5.463ValVal: 5.463 ± 0.076	0.877ValTrp: 0.877 ± 0.022	1.739ValTyr: 1.739 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.118TrpAla: 1.118 ± 0.025	0.153TrpCys: 0.153 ± 0.009	0.625TrpAsp: 0.625 ± 0.017	0.544TrpGlu: 0.544 ± 0.019	0.524TrpPhe: 0.524 ± 0.016	0.816TrpGly: 0.816 ± 0.023	0.358TrpHis: 0.358 ± 0.012	0.604TrpIle: 0.604 ± 0.017	0.495TrpLys: 0.495 ± 0.017	1.837TrpLeu: 1.837 ± 0.035	0.422TrpMet: 0.422 ± 0.015	0.475TrpAsn: 0.475 ± 0.014	0.576TrpPro: 0.576 ± 0.018	0.792TrpGln: 0.792 ± 0.018	1.101TrpArg: 1.101 ± 0.027	0.762TrpSer: 0.762 ± 0.022	0.711TrpThr: 0.711 ± 0.027	0.795TrpVal: 0.795 ± 0.021	0.234TrpTrp: 0.234 ± 0.012	0.311TrpTyr: 0.311 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.969TyrAla: 2.969 ± 0.039	0.279TyrCys: 0.279 ± 0.014	1.611TyrAsp: 1.611 ± 0.042	1.172TyrGlu: 1.172 ± 0.025	1.06TyrPhe: 1.06 ± 0.024	2.256TyrGly: 2.256 ± 0.035	0.574TyrHis: 0.574 ± 0.017	1.02TyrIle: 1.02 ± 0.023	0.908TyrLys: 0.908 ± 0.024	2.564TyrLeu: 2.564 ± 0.035	0.552TyrMet: 0.552 ± 0.014	0.833TyrAsn: 0.833 ± 0.022	1.248TyrPro: 1.248 ± 0.027	1.128TyrGln: 1.128 ± 0.024	1.85TyrArg: 1.85 ± 0.032	1.56TyrSer: 1.56 ± 0.031	1.581TyrThr: 1.581 ± 0.036	1.887TyrVal: 1.887 ± 0.035	0.419TyrTrp: 0.419 ± 0.013	0.819TyrTyr: 0.819 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5918 proteins (2124225 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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