Amino acid dipepetide frequency for Paracoccus contaminans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	25.915AlaAla: 25.915 ± 0.335	1.203AlaCys: 1.203 ± 0.041	8.332AlaAsp: 8.332 ± 0.108	9.185AlaGlu: 9.185 ± 0.13	4.037AlaPhe: 4.037 ± 0.065	14.577AlaGly: 14.577 ± 0.16	2.51AlaHis: 2.51 ± 0.068	6.017AlaIle: 6.017 ± 0.078	2.637AlaLys: 2.637 ± 0.084	16.176AlaLeu: 16.176 ± 0.2	4.279AlaMet: 4.279 ± 0.065	2.423AlaAsn: 2.423 ± 0.048	8.186AlaPro: 8.186 ± 0.141	5.282AlaGln: 5.282 ± 0.09	12.406AlaArg: 12.406 ± 0.149	5.747AlaSer: 5.747 ± 0.08	5.719AlaThr: 5.719 ± 0.095	9.641AlaVal: 9.641 ± 0.116	1.868AlaTrp: 1.868 ± 0.05	2.27AlaTyr: 2.27 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	1.135CysAla: 1.135 ± 0.043	0.121CysCys: 0.121 ± 0.012	0.511CysAsp: 0.511 ± 0.027	0.36CysGlu: 0.36 ± 0.022	0.258CysPhe: 0.258 ± 0.017	0.955CysGly: 0.955 ± 0.038	0.222CysHis: 0.222 ± 0.016	0.363CysIle: 0.363 ± 0.024	0.146CysLys: 0.146 ± 0.016	0.764CysLeu: 0.764 ± 0.035	0.137CysMet: 0.137 ± 0.012	0.146CysAsn: 0.146 ± 0.013	0.543CysPro: 0.543 ± 0.027	0.203CysGln: 0.203 ± 0.015	0.615CysArg: 0.615 ± 0.029	0.387CysSer: 0.387 ± 0.023	0.347CysThr: 0.347 ± 0.022	0.502CysVal: 0.502 ± 0.024	0.152CysTrp: 0.152 ± 0.013	0.147CysTyr: 0.147 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	8.135AspAla: 8.135 ± 0.108	0.455AspCys: 0.455 ± 0.025	3.238AspAsp: 3.238 ± 0.077	3.508AspGlu: 3.508 ± 0.067	2.127AspPhe: 2.127 ± 0.05	5.787AspGly: 5.787 ± 0.1	1.46AspHis: 1.46 ± 0.048	2.605AspIle: 2.605 ± 0.05	1.404AspLys: 1.404 ± 0.045	6.34AspLeu: 6.34 ± 0.094	1.471AspMet: 1.471 ± 0.042	1.096AspAsn: 1.096 ± 0.039	4.221AspPro: 4.221 ± 0.077	1.843AspGln: 1.843 ± 0.048	5.062AspArg: 5.062 ± 0.088	2.133AspSer: 2.133 ± 0.052	2.472AspThr: 2.472 ± 0.066	3.551AspVal: 3.551 ± 0.067	1.218AspTrp: 1.218 ± 0.045	1.375AspTyr: 1.375 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	7.907GluAla: 7.907 ± 0.131	0.296GluCys: 0.296 ± 0.019	2.713GluAsp: 2.713 ± 0.062	2.368GluGlu: 2.368 ± 0.069	1.272GluPhe: 1.272 ± 0.042	5.01GluGly: 5.01 ± 0.075	0.905GluHis: 0.905 ± 0.038	3.086GluIle: 3.086 ± 0.066	1.436GluLys: 1.436 ± 0.046	4.558GluLeu: 4.558 ± 0.073	1.354GluMet: 1.354 ± 0.042	1.235GluAsn: 1.235 ± 0.041	2.549GluPro: 2.549 ± 0.059	1.833GluGln: 1.833 ± 0.051	4.736GluArg: 4.736 ± 0.077	1.958GluSer: 1.958 ± 0.053	2.974GluThr: 2.974 ± 0.067	3.513GluVal: 3.513 ± 0.066	0.693GluTrp: 0.693 ± 0.033	0.885GluTyr: 0.885 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	4.409PheAla: 4.409 ± 0.082	0.336PheCys: 0.336 ± 0.022	2.482PheAsp: 2.482 ± 0.047	1.616PheGlu: 1.616 ± 0.05	1.087PhePhe: 1.087 ± 0.045	3.221PheGly: 3.221 ± 0.073	0.691PheHis: 0.691 ± 0.028	1.286PheIle: 1.286 ± 0.039	0.679PheLys: 0.679 ± 0.032	2.979PheLeu: 2.979 ± 0.064	0.709PheMet: 0.709 ± 0.029	0.771PheAsn: 0.771 ± 0.032	1.418PhePro: 1.418 ± 0.044	0.897PheGln: 0.897 ± 0.036	2.184PheArg: 2.184 ± 0.053	1.689PheSer: 1.689 ± 0.045	1.707PheThr: 1.707 ± 0.049	2.358PheVal: 2.358 ± 0.056	0.51PheTrp: 0.51 ± 0.025	0.728PheTyr: 0.728 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	12.917GlyAla: 12.917 ± 0.145	0.839GlyCys: 0.839 ± 0.034	4.971GlyAsp: 4.971 ± 0.081	4.737GlyGlu: 4.737 ± 0.079	3.512GlyPhe: 3.512 ± 0.073	8.619GlyGly: 8.619 ± 0.143	2.001GlyHis: 2.001 ± 0.047	4.491GlyIle: 4.491 ± 0.071	2.741GlyLys: 2.741 ± 0.066	9.715GlyLeu: 9.715 ± 0.118	2.815GlyMet: 2.815 ± 0.06	2.002GlyAsn: 2.002 ± 0.064	4.537GlyPro: 4.537 ± 0.078	3.431GlyGln: 3.431 ± 0.065	8.071GlyArg: 8.071 ± 0.12	4.299GlySer: 4.299 ± 0.078	5.038GlyThr: 5.038 ± 0.091	6.151GlyVal: 6.151 ± 0.088	1.767GlyTrp: 1.767 ± 0.05	2.036GlyTyr: 2.036 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.602HisAla: 2.602 ± 0.067	0.2HisCys: 0.2 ± 0.016	1.337HisAsp: 1.337 ± 0.04	0.962HisGlu: 0.962 ± 0.031	0.703HisPhe: 0.703 ± 0.032	2.034HisGly: 2.034 ± 0.052	0.571HisHis: 0.571 ± 0.031	0.759HisIle: 0.759 ± 0.034	0.367HisLys: 0.367 ± 0.02	2.049HisLeu: 2.049 ± 0.054	0.49HisMet: 0.49 ± 0.025	0.378HisAsn: 0.378 ± 0.021	1.475HisPro: 1.475 ± 0.043	0.581HisGln: 0.581 ± 0.024	1.512HisArg: 1.512 ± 0.044	0.731HisSer: 0.731 ± 0.032	0.652HisThr: 0.652 ± 0.025	1.525HisVal: 1.525 ± 0.048	0.344HisTrp: 0.344 ± 0.019	0.511HisTyr: 0.511 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	7.461IleAla: 7.461 ± 0.105	0.459IleCys: 0.459 ± 0.025	3.299IleAsp: 3.299 ± 0.057	3.152IleGlu: 3.152 ± 0.065	1.29IlePhe: 1.29 ± 0.041	4.759IleGly: 4.759 ± 0.078	0.922IleHis: 0.922 ± 0.033	1.821IleIle: 1.821 ± 0.051	0.957IleLys: 0.957 ± 0.034	4.113IleLeu: 4.113 ± 0.074	0.999IleMet: 0.999 ± 0.034	1.045IleAsn: 1.045 ± 0.035	2.217IlePro: 2.217 ± 0.054	0.979IleGln: 0.979 ± 0.034	3.599IleArg: 3.599 ± 0.07	2.107IleSer: 2.107 ± 0.05	2.551IleThr: 2.551 ± 0.062	3.57IleVal: 3.57 ± 0.07	0.577IleTrp: 0.577 ± 0.027	0.886IleTyr: 0.886 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.335LysAla: 3.335 ± 0.088	0.115LysCys: 0.115 ± 0.012	1.348LysAsp: 1.348 ± 0.047	0.964LysGlu: 0.964 ± 0.043	0.574LysPhe: 0.574 ± 0.028	2.315LysGly: 2.315 ± 0.068	0.395LysHis: 0.395 ± 0.022	1.029LysIle: 1.029 ± 0.048	0.73LysLys: 0.73 ± 0.034	2.03LysLeu: 2.03 ± 0.059	0.559LysMet: 0.559 ± 0.03	0.531LysAsn: 0.531 ± 0.025	1.37LysPro: 1.37 ± 0.037	0.641LysGln: 0.641 ± 0.026	1.574LysArg: 1.574 ± 0.049	1.225LysSer: 1.225 ± 0.04	1.307LysThr: 1.307 ± 0.037	1.662LysVal: 1.662 ± 0.053	0.275LysTrp: 0.275 ± 0.019	0.436LysTyr: 0.436 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	15.939LeuAla: 15.939 ± 0.188	0.893LeuCys: 0.893 ± 0.035	6.54LeuAsp: 6.54 ± 0.097	4.02LeuGlu: 4.02 ± 0.07	3.048LeuPhe: 3.048 ± 0.061	8.973LeuGly: 8.973 ± 0.125	1.773LeuHis: 1.773 ± 0.049	4.726LeuIle: 4.726 ± 0.076	2.225LeuLys: 2.225 ± 0.065	8.51LeuLeu: 8.51 ± 0.133	2.563LeuMet: 2.563 ± 0.056	2.315LeuAsn: 2.315 ± 0.056	6.323LeuPro: 6.323 ± 0.108	2.238LeuGln: 2.238 ± 0.057	8.206LeuArg: 8.206 ± 0.108	6.231LeuSer: 6.231 ± 0.093	5.794LeuThr: 5.794 ± 0.091	7.074LeuVal: 7.074 ± 0.103	1.317LeuTrp: 1.317 ± 0.041	1.761LeuTyr: 1.761 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	3.843MetAla: 3.843 ± 0.075	0.139MetCys: 0.139 ± 0.015	1.38MetAsp: 1.38 ± 0.039	1.065MetGlu: 1.065 ± 0.042	0.714MetPhe: 0.714 ± 0.027	2.358MetGly: 2.358 ± 0.049	0.412MetHis: 0.412 ± 0.024	1.426MetIle: 1.426 ± 0.046	0.781MetLys: 0.781 ± 0.033	2.663MetLeu: 2.663 ± 0.063	0.759MetMet: 0.759 ± 0.033	0.772MetAsn: 0.772 ± 0.027	1.646MetPro: 1.646 ± 0.047	0.953MetGln: 0.953 ± 0.033	2.161MetArg: 2.161 ± 0.053	1.395MetSer: 1.395 ± 0.041	1.927MetThr: 1.927 ± 0.053	1.761MetVal: 1.761 ± 0.047	0.213MetTrp: 0.213 ± 0.018	0.259MetTyr: 0.259 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.972AsnAla: 2.972 ± 0.062	0.186AsnCys: 0.186 ± 0.014	1.22AsnAsp: 1.22 ± 0.053	0.882AsnGlu: 0.882 ± 0.03	0.661AsnPhe: 0.661 ± 0.029	1.977AsnGly: 1.977 ± 0.054	0.442AsnHis: 0.442 ± 0.023	1.05AsnIle: 1.05 ± 0.035	0.471AsnLys: 0.471 ± 0.023	2.118AsnLeu: 2.118 ± 0.055	0.536AsnMet: 0.536 ± 0.027	0.481AsnAsn: 0.481 ± 0.026	1.765AsnPro: 1.765 ± 0.045	0.548AsnGln: 0.548 ± 0.025	1.682AsnArg: 1.682 ± 0.042	0.815AsnSer: 0.815 ± 0.033	1.046AsnThr: 1.046 ± 0.036	1.501AsnVal: 1.501 ± 0.048	0.387AsnTrp: 0.387 ± 0.022	0.458AsnTyr: 0.458 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	9.807ProAla: 9.807 ± 0.164	0.435ProCys: 0.435 ± 0.023	4.309ProAsp: 4.309 ± 0.084	3.55ProGlu: 3.55 ± 0.071	1.787ProPhe: 1.787 ± 0.043	5.954ProGly: 5.954 ± 0.091	1.162ProHis: 1.162 ± 0.038	2.024ProIle: 2.024 ± 0.051	1.058ProLys: 1.058 ± 0.039	5.154ProLeu: 5.154 ± 0.092	1.361ProMet: 1.361 ± 0.04	1.021ProAsn: 1.021 ± 0.034	3.441ProPro: 3.441 ± 0.094	2.148ProGln: 2.148 ± 0.049	3.991ProArg: 3.991 ± 0.079	2.526ProSer: 2.526 ± 0.059	2.196ProThr: 2.196 ± 0.056	4.77ProVal: 4.77 ± 0.082	0.805ProTrp: 0.805 ± 0.032	1.013ProTyr: 1.013 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	4.817GlnAla: 4.817 ± 0.09	0.158GlnCys: 0.158 ± 0.012	1.653GlnAsp: 1.653 ± 0.044	1.117GlnGlu: 1.117 ± 0.036	0.919GlnPhe: 0.919 ± 0.034	3.317GlnGly: 3.317 ± 0.078	0.546GlnHis: 0.546 ± 0.026	1.741GlnIle: 1.741 ± 0.05	0.792GlnLys: 0.792 ± 0.041	2.659GlnLeu: 2.659 ± 0.062	1.02GlnMet: 1.02 ± 0.038	0.728GlnAsn: 0.728 ± 0.03	2.109GlnPro: 2.109 ± 0.055	1.124GlnGln: 1.124 ± 0.04	2.48GlnArg: 2.48 ± 0.066	1.539GlnSer: 1.539 ± 0.044	1.605GlnThr: 1.605 ± 0.045	2.457GlnVal: 2.457 ± 0.054	0.389GlnTrp: 0.389 ± 0.02	0.489GlnTyr: 0.489 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	11.13ArgAla: 11.13 ± 0.139	0.532ArgCys: 0.532 ± 0.027	4.498ArgAsp: 4.498 ± 0.073	3.839ArgGlu: 3.839 ± 0.069	2.766ArgPhe: 2.766 ± 0.058	6.07ArgGly: 6.07 ± 0.094	1.861ArgHis: 1.861 ± 0.045	4.677ArgIle: 4.677 ± 0.073	1.834ArgLys: 1.834 ± 0.053	9.495ArgLeu: 9.495 ± 0.137	2.508ArgMet: 2.508 ± 0.056	1.698ArgAsn: 1.698 ± 0.042	4.864ArgPro: 4.864 ± 0.08	2.802ArgGln: 2.802 ± 0.068	7.159ArgArg: 7.159 ± 0.113	3.526ArgSer: 3.526 ± 0.063	3.368ArgThr: 3.368 ± 0.058	5.154ArgVal: 5.154 ± 0.09	1.267ArgTrp: 1.267 ± 0.037	1.505ArgTyr: 1.505 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.244SerAla: 6.244 ± 0.095	0.382SerCys: 0.382 ± 0.023	2.659SerAsp: 2.659 ± 0.053	2.008SerGlu: 2.008 ± 0.047	1.855SerPhe: 1.855 ± 0.046	5.21SerGly: 5.21 ± 0.071	0.921SerHis: 0.921 ± 0.032	1.965SerIle: 1.965 ± 0.057	0.922SerLys: 0.922 ± 0.036	4.615SerLeu: 4.615 ± 0.082	1.164SerMet: 1.164 ± 0.031	0.974SerAsn: 0.974 ± 0.038	2.749SerPro: 2.749 ± 0.066	1.256SerGln: 1.256 ± 0.037	3.394SerArg: 3.394 ± 0.067	2.0SerSer: 2.0 ± 0.061	2.059SerThr: 2.059 ± 0.05	3.367SerVal: 3.367 ± 0.065	0.737SerTrp: 0.737 ± 0.027	1.027SerTyr: 1.027 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	6.635ThrAla: 6.635 ± 0.106	0.427ThrCys: 0.427 ± 0.024	2.878ThrAsp: 2.878 ± 0.055	2.468ThrGlu: 2.468 ± 0.051	1.521ThrPhe: 1.521 ± 0.043	5.411ThrGly: 5.411 ± 0.082	0.935ThrHis: 0.935 ± 0.035	2.458ThrIle: 2.458 ± 0.059	0.856ThrLys: 0.856 ± 0.032	5.408ThrLeu: 5.408 ± 0.083	1.083ThrMet: 1.083 ± 0.037	1.002ThrAsn: 1.002 ± 0.04	3.3ThrPro: 3.3 ± 0.057	1.395ThrGln: 1.395 ± 0.036	3.686ThrArg: 3.686 ± 0.065	2.073ThrSer: 2.073 ± 0.051	2.5ThrThr: 2.5 ± 0.066	3.922ThrVal: 3.922 ± 0.079	0.585ThrTrp: 0.585 ± 0.026	0.923ThrTyr: 0.923 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	9.128ValAla: 9.128 ± 0.118	0.523ValCys: 0.523 ± 0.025	3.821ValAsp: 3.821 ± 0.068	4.008ValGlu: 4.008 ± 0.089	2.406ValPhe: 2.406 ± 0.049	5.105ValGly: 5.105 ± 0.096	1.288ValHis: 1.288 ± 0.032	3.965ValIle: 3.965 ± 0.078	1.587ValLys: 1.587 ± 0.055	7.421ValLeu: 7.421 ± 0.101	2.023ValMet: 2.023 ± 0.049	1.772ValAsn: 1.772 ± 0.05	4.061ValPro: 4.061 ± 0.069	2.196ValGln: 2.196 ± 0.051	5.084ValArg: 5.084 ± 0.08	3.519ValSer: 3.519 ± 0.069	4.499ValThr: 4.499 ± 0.089	5.327ValVal: 5.327 ± 0.083	0.984ValTrp: 0.984 ± 0.036	1.303ValTyr: 1.303 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	1.643TrpAla: 1.643 ± 0.05	0.12TrpCys: 0.12 ± 0.012	0.845TrpAsp: 0.845 ± 0.036	0.517TrpGlu: 0.517 ± 0.027	0.554TrpPhe: 0.554 ± 0.026	1.102TrpGly: 1.102 ± 0.041	0.317TrpHis: 0.317 ± 0.02	0.652TrpIle: 0.652 ± 0.028	0.388TrpLys: 0.388 ± 0.023	1.836TrpLeu: 1.836 ± 0.052	0.422TrpMet: 0.422 ± 0.021	0.394TrpAsn: 0.394 ± 0.022	0.761TrpPro: 0.761 ± 0.032	0.694TrpGln: 0.694 ± 0.026	1.386TrpArg: 1.386 ± 0.045	0.745TrpSer: 0.745 ± 0.029	0.915TrpThr: 0.915 ± 0.036	0.86TrpVal: 0.86 ± 0.033	0.271TrpTrp: 0.271 ± 0.016	0.241TrpTyr: 0.241 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.438TyrAla: 2.438 ± 0.044	0.195TyrCys: 0.195 ± 0.015	1.467TyrAsp: 1.467 ± 0.039	0.954TyrGlu: 0.954 ± 0.038	0.665TyrPhe: 0.665 ± 0.03	1.934TyrGly: 1.934 ± 0.052	0.451TyrHis: 0.451 ± 0.024	0.624TyrIle: 0.624 ± 0.029	0.403TyrLys: 0.403 ± 0.023	1.867TyrLeu: 1.867 ± 0.05	0.373TyrMet: 0.373 ± 0.02	0.416TyrAsn: 0.416 ± 0.024	0.975TyrPro: 0.975 ± 0.032	0.612TyrGln: 0.612 ± 0.029	1.57TyrArg: 1.57 ± 0.044	0.863TyrSer: 0.863 ± 0.035	0.792TyrThr: 0.792 ± 0.026	1.353TyrVal: 1.353 ± 0.037	0.302TyrTrp: 0.302 ± 0.018	0.462TyrTyr: 0.462 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2745 proteins (868674 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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