Amino acid dipepetide frequency for BeAn 58058 virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.076AlaAla: 1.076 ± 0.206
0.38AlaCys: 0.38 ± 0.085
1.223AlaAsp: 1.223 ± 0.17
0.97AlaGlu: 0.97 ± 0.162
1.097AlaPhe: 1.097 ± 0.15
0.928AlaGly: 0.928 ± 0.168
0.464AlaHis: 0.464 ± 0.099
2.89AlaIle: 2.89 ± 0.23
1.835AlaLys: 1.835 ± 0.178
2.236AlaLeu: 2.236 ± 0.224
0.485AlaMet: 0.485 ± 0.094
1.709AlaAsn: 1.709 ± 0.198
0.78AlaPro: 0.78 ± 0.136
0.38AlaGln: 0.38 ± 0.077
0.865AlaArg: 0.865 ± 0.149
1.898AlaSer: 1.898 ± 0.171
1.624AlaThr: 1.624 ± 0.154
1.561AlaVal: 1.561 ± 0.173
0.127AlaTrp: 0.127 ± 0.052
1.16AlaTyr: 1.16 ± 0.162
0.0AlaXaa: 0.0 ± 0.0
Cys
0.506CysAla: 0.506 ± 0.099
0.485CysCys: 0.485 ± 0.094
1.139CysAsp: 1.139 ± 0.143
1.118CysGlu: 1.118 ± 0.156
0.823CysPhe: 0.823 ± 0.133
0.654CysGly: 0.654 ± 0.104
0.211CysHis: 0.211 ± 0.064
2.426CysIle: 2.426 ± 0.216
2.194CysLys: 2.194 ± 0.212
1.645CysLeu: 1.645 ± 0.171
0.422CysMet: 0.422 ± 0.096
1.983CysAsn: 1.983 ± 0.194
0.485CysPro: 0.485 ± 0.091
0.337CysGln: 0.337 ± 0.077
0.612CysArg: 0.612 ± 0.122
1.392CysSer: 1.392 ± 0.177
1.181CysThr: 1.181 ± 0.225
1.076CysVal: 1.076 ± 0.175
0.148CysTrp: 0.148 ± 0.068
1.519CysTyr: 1.519 ± 0.187
0.0CysXaa: 0.0 ± 0.0
Asp
1.582AspAla: 1.582 ± 0.184
1.076AspCys: 1.076 ± 0.149
5.083AspAsp: 5.083 ± 0.347
3.776AspGlu: 3.776 ± 0.337
3.248AspPhe: 3.248 ± 0.271
2.426AspGly: 2.426 ± 0.266
0.401AspHis: 0.401 ± 0.082
9.977AspIle: 9.977 ± 0.424
5.737AspLys: 5.737 ± 0.393
4.598AspLeu: 4.598 ± 0.371
1.498AspMet: 1.498 ± 0.144
5.8AspAsn: 5.8 ± 0.357
1.413AspPro: 1.413 ± 0.132
0.78AspGln: 0.78 ± 0.131
1.73AspArg: 1.73 ± 0.178
3.691AspSer: 3.691 ± 0.271
3.691AspThr: 3.691 ± 0.21
3.776AspVal: 3.776 ± 0.277
0.359AspTrp: 0.359 ± 0.079
3.206AspTyr: 3.206 ± 0.302
0.0AspXaa: 0.0 ± 0.0
Glu
1.118GluAla: 1.118 ± 0.149
1.034GluCys: 1.034 ± 0.146
2.805GluAsp: 2.805 ± 0.221
2.721GluGlu: 2.721 ± 0.251
2.7GluPhe: 2.7 ± 0.262
1.034GluGly: 1.034 ± 0.196
0.738GluHis: 0.738 ± 0.111
5.442GluIle: 5.442 ± 0.321
4.429GluLys: 4.429 ± 0.313
4.915GluLeu: 4.915 ± 0.318
1.266GluMet: 1.266 ± 0.172
4.872GluAsn: 4.872 ± 0.279
1.582GluPro: 1.582 ± 0.2
1.181GluGln: 1.181 ± 0.153
1.519GluArg: 1.519 ± 0.212
3.185GluSer: 3.185 ± 0.232
3.375GluThr: 3.375 ± 0.263
2.13GluVal: 2.13 ± 0.204
0.38GluTrp: 0.38 ± 0.082
3.902GluTyr: 3.902 ± 0.275
0.0GluXaa: 0.0 ± 0.0
Phe
0.97PheAla: 0.97 ± 0.152
1.371PheCys: 1.371 ± 0.184
3.522PheAsp: 3.522 ± 0.297
2.299PheGlu: 2.299 ± 0.186
2.447PhePhe: 2.447 ± 0.219
2.257PheGly: 2.257 ± 0.205
0.696PheHis: 0.696 ± 0.122
6.349PheIle: 6.349 ± 0.436
4.851PheLys: 4.851 ± 0.323
4.408PheLeu: 4.408 ± 0.328
1.287PheMet: 1.287 ± 0.173
5.168PheAsn: 5.168 ± 0.272
1.455PhePro: 1.455 ± 0.148
0.696PheGln: 0.696 ± 0.115
1.308PheArg: 1.308 ± 0.173
4.219PheSer: 4.219 ± 0.27
2.805PheThr: 2.805 ± 0.239
2.911PheVal: 2.911 ± 0.254
0.443PheTrp: 0.443 ± 0.102
2.278PheTyr: 2.278 ± 0.221
0.0PheXaa: 0.0 ± 0.0
Gly
1.055GlyAla: 1.055 ± 0.162
0.633GlyCys: 0.633 ± 0.104
2.004GlyAsp: 2.004 ± 0.17
1.624GlyGlu: 1.624 ± 0.183
1.814GlyPhe: 1.814 ± 0.203
1.814GlyGly: 1.814 ± 0.255
0.295GlyHis: 0.295 ± 0.074
4.155GlyIle: 4.155 ± 0.272
3.565GlyLys: 3.565 ± 0.268
2.573GlyLeu: 2.573 ± 0.197
0.696GlyMet: 0.696 ± 0.111
2.552GlyAsn: 2.552 ± 0.218
0.633GlyPro: 0.633 ± 0.097
0.443GlyGln: 0.443 ± 0.079
1.476GlyArg: 1.476 ± 0.227
2.362GlySer: 2.362 ± 0.252
1.666GlyThr: 1.666 ± 0.211
1.941GlyVal: 1.941 ± 0.181
0.211GlyTrp: 0.211 ± 0.07
2.468GlyTyr: 2.468 ± 0.225
0.0GlyXaa: 0.0 ± 0.0
His
0.337HisAla: 0.337 ± 0.081
0.464HisCys: 0.464 ± 0.122
1.012HisAsp: 1.012 ± 0.133
0.591HisGlu: 0.591 ± 0.095
0.759HisPhe: 0.759 ± 0.114
0.654HisGly: 0.654 ± 0.102
0.253HisHis: 0.253 ± 0.07
2.383HisIle: 2.383 ± 0.228
1.35HisLys: 1.35 ± 0.158
1.308HisLeu: 1.308 ± 0.159
0.696HisMet: 0.696 ± 0.102
1.118HisAsn: 1.118 ± 0.149
0.316HisPro: 0.316 ± 0.091
0.337HisGln: 0.337 ± 0.09
0.38HisArg: 0.38 ± 0.091
1.118HisSer: 1.118 ± 0.16
0.991HisThr: 0.991 ± 0.155
1.097HisVal: 1.097 ± 0.127
0.211HisTrp: 0.211 ± 0.077
0.886HisTyr: 0.886 ± 0.147
0.0HisXaa: 0.0 ± 0.0
Ile
2.468IleAla: 2.468 ± 0.222
2.215IleCys: 2.215 ± 0.2
8.268IleAsp: 8.268 ± 0.372
6.011IleGlu: 6.011 ± 0.389
6.813IlePhe: 6.813 ± 0.364
3.691IleGly: 3.691 ± 0.298
2.341IleHis: 2.341 ± 0.248
12.086IleIle: 12.086 ± 0.555
10.821IleLys: 10.821 ± 0.501
10.863IleLeu: 10.863 ± 0.509
2.615IleMet: 2.615 ± 0.262
11.559IleAsn: 11.559 ± 0.559
3.544IlePro: 3.544 ± 0.284
2.215IleGln: 2.215 ± 0.221
3.733IleArg: 3.733 ± 0.277
9.239IleSer: 9.239 ± 0.408
6.117IleThr: 6.117 ± 0.328
6.243IleVal: 6.243 ± 0.307
0.443IleTrp: 0.443 ± 0.08
6.518IleTyr: 6.518 ± 0.351
0.0IleXaa: 0.0 ± 0.0
Lys
1.434LysAla: 1.434 ± 0.192
1.919LysCys: 1.919 ± 0.193
5.632LysAsp: 5.632 ± 0.351
4.64LysGlu: 4.64 ± 0.329
3.797LysPhe: 3.797 ± 0.327
2.257LysGly: 2.257 ± 0.218
1.941LysHis: 1.941 ± 0.215
9.998LysIle: 9.998 ± 0.418
8.943LysLys: 8.943 ± 0.462
8.057LysLeu: 8.057 ± 0.392
2.299LysMet: 2.299 ± 0.215
9.175LysAsn: 9.175 ± 0.516
2.173LysPro: 2.173 ± 0.266
1.962LysGln: 1.962 ± 0.232
2.932LysArg: 2.932 ± 0.265
6.623LysSer: 6.623 ± 0.316
5.168LysThr: 5.168 ± 0.277
4.176LysVal: 4.176 ± 0.273
0.78LysTrp: 0.78 ± 0.136
6.834LysTyr: 6.834 ± 0.418
0.0LysXaa: 0.0 ± 0.0
Leu
2.088LeuAla: 2.088 ± 0.208
1.814LeuCys: 1.814 ± 0.221
5.147LeuAsp: 5.147 ± 0.265
4.746LeuGlu: 4.746 ± 0.358
5.252LeuPhe: 5.252 ± 0.334
2.573LeuGly: 2.573 ± 0.244
2.004LeuHis: 2.004 ± 0.217
8.543LeuIle: 8.543 ± 0.468
7.171LeuLys: 7.171 ± 0.359
8.669LeuLeu: 8.669 ± 0.518
1.941LeuMet: 1.941 ± 0.182
7.003LeuAsn: 7.003 ± 0.403
2.573LeuPro: 2.573 ± 0.26
1.814LeuGln: 1.814 ± 0.201
2.32LeuArg: 2.32 ± 0.277
8.416LeuSer: 8.416 ± 0.428
4.514LeuThr: 4.514 ± 0.321
4.472LeuVal: 4.472 ± 0.32
0.295LeuTrp: 0.295 ± 0.11
5.695LeuTyr: 5.695 ± 0.357
0.0LeuXaa: 0.0 ± 0.0
Met
0.78MetAla: 0.78 ± 0.135
0.38MetCys: 0.38 ± 0.09
1.413MetAsp: 1.413 ± 0.188
1.202MetGlu: 1.202 ± 0.156
1.455MetPhe: 1.455 ± 0.171
1.034MetGly: 1.034 ± 0.155
0.274MetHis: 0.274 ± 0.077
1.983MetIle: 1.983 ± 0.224
2.194MetLys: 2.194 ± 0.252
2.594MetLeu: 2.594 ± 0.23
0.654MetMet: 0.654 ± 0.114
1.498MetAsn: 1.498 ± 0.182
0.654MetPro: 0.654 ± 0.098
0.443MetGln: 0.443 ± 0.08
0.696MetArg: 0.696 ± 0.13
1.877MetSer: 1.877 ± 0.225
1.244MetThr: 1.244 ± 0.14
1.244MetVal: 1.244 ± 0.16
0.127MetTrp: 0.127 ± 0.055
1.709MetTyr: 1.709 ± 0.208
0.0MetXaa: 0.0 ± 0.0
Asn
1.666AsnAla: 1.666 ± 0.205
1.223AsnCys: 1.223 ± 0.164
6.328AsnAsp: 6.328 ± 0.382
4.493AsnGlu: 4.493 ± 0.324
3.818AsnPhe: 3.818 ± 0.263
3.354AsnGly: 3.354 ± 0.258
1.308AsnHis: 1.308 ± 0.158
13.71AsnIle: 13.71 ± 0.518
9.239AsnLys: 9.239 ± 0.463
5.695AsnLeu: 5.695 ± 0.344
2.32AsnMet: 2.32 ± 0.251
10.736AsnAsn: 10.736 ± 0.507
2.13AsnPro: 2.13 ± 0.213
1.455AsnGln: 1.455 ± 0.183
2.721AsnArg: 2.721 ± 0.243
5.526AsnSer: 5.526 ± 0.361
5.969AsnThr: 5.969 ± 0.36
5.21AsnVal: 5.21 ± 0.328
0.548AsnTrp: 0.548 ± 0.111
4.64AsnTyr: 4.64 ± 0.334
0.0AsnXaa: 0.0 ± 0.0
Pro
0.78ProAla: 0.78 ± 0.127
0.57ProCys: 0.57 ± 0.117
1.73ProAsp: 1.73 ± 0.167
1.941ProGlu: 1.941 ± 0.207
1.645ProPhe: 1.645 ± 0.211
0.949ProGly: 0.949 ± 0.142
0.443ProHis: 0.443 ± 0.11
2.995ProIle: 2.995 ± 0.248
2.383ProLys: 2.383 ± 0.269
2.573ProLeu: 2.573 ± 0.226
0.422ProMet: 0.422 ± 0.087
1.941ProAsn: 1.941 ± 0.19
0.991ProPro: 0.991 ± 0.163
0.654ProGln: 0.654 ± 0.132
1.012ProArg: 1.012 ± 0.141
1.941ProSer: 1.941 ± 0.165
1.582ProThr: 1.582 ± 0.16
1.645ProVal: 1.645 ± 0.17
0.169ProTrp: 0.169 ± 0.056
1.392ProTyr: 1.392 ± 0.177
0.0ProXaa: 0.0 ± 0.0
Gln
0.316GlnAla: 0.316 ± 0.093
0.485GlnCys: 0.485 ± 0.107
1.16GlnAsp: 1.16 ± 0.157
0.802GlnGlu: 0.802 ± 0.13
0.759GlnPhe: 0.759 ± 0.121
0.401GlnGly: 0.401 ± 0.096
0.316GlnHis: 0.316 ± 0.085
1.687GlnIle: 1.687 ± 0.208
1.856GlnLys: 1.856 ± 0.202
1.687GlnLeu: 1.687 ± 0.218
0.422GlnMet: 0.422 ± 0.097
1.54GlnAsn: 1.54 ± 0.222
0.548GlnPro: 0.548 ± 0.167
0.57GlnGln: 0.57 ± 0.128
0.633GlnArg: 0.633 ± 0.118
1.413GlnSer: 1.413 ± 0.171
1.055GlnThr: 1.055 ± 0.187
0.802GlnVal: 0.802 ± 0.121
0.211GlnTrp: 0.211 ± 0.071
1.35GlnTyr: 1.35 ± 0.192
0.0GlnXaa: 0.0 ± 0.0
Arg
0.802ArgAla: 0.802 ± 0.125
0.738ArgCys: 0.738 ± 0.126
1.561ArgAsp: 1.561 ± 0.199
1.582ArgGlu: 1.582 ± 0.201
1.877ArgPhe: 1.877 ± 0.174
1.034ArgGly: 1.034 ± 0.181
0.527ArgHis: 0.527 ± 0.1
2.826ArgIle: 2.826 ± 0.223
2.594ArgLys: 2.594 ± 0.253
3.058ArgLeu: 3.058 ± 0.286
0.57ArgMet: 0.57 ± 0.097
2.278ArgAsn: 2.278 ± 0.222
0.991ArgPro: 0.991 ± 0.138
0.633ArgGln: 0.633 ± 0.11
1.392ArgArg: 1.392 ± 0.19
2.447ArgSer: 2.447 ± 0.215
1.709ArgThr: 1.709 ± 0.22
1.73ArgVal: 1.73 ± 0.217
0.211ArgTrp: 0.211 ± 0.071
2.257ArgTyr: 2.257 ± 0.219
0.0ArgXaa: 0.0 ± 0.0
Ser
2.109SerAla: 2.109 ± 0.225
1.582SerCys: 1.582 ± 0.198
4.999SerAsp: 4.999 ± 0.371
3.649SerGlu: 3.649 ± 0.288
3.923SerPhe: 3.923 ± 0.313
2.615SerGly: 2.615 ± 0.255
0.928SerHis: 0.928 ± 0.142
9.892SerIle: 9.892 ± 0.458
6.771SerLys: 6.771 ± 0.34
5.547SerLeu: 5.547 ± 0.361
1.687SerMet: 1.687 ± 0.156
6.665SerAsn: 6.665 ± 0.356
1.898SerPro: 1.898 ± 0.199
1.308SerGln: 1.308 ± 0.198
2.51SerArg: 2.51 ± 0.255
5.653SerSer: 5.653 ± 0.406
4.24SerThr: 4.24 ± 0.416
4.155SerVal: 4.155 ± 0.304
0.359SerTrp: 0.359 ± 0.091
4.282SerTyr: 4.282 ± 0.339
0.0SerXaa: 0.0 ± 0.0
Thr
1.54ThrAla: 1.54 ± 0.165
1.223ThrCys: 1.223 ± 0.177
3.375ThrAsp: 3.375 ± 0.243
2.721ThrGlu: 2.721 ± 0.237
3.143ThrPhe: 3.143 ± 0.247
1.877ThrGly: 1.877 ± 0.25
1.076ThrHis: 1.076 ± 0.153
6.265ThrIle: 6.265 ± 0.393
4.493ThrLys: 4.493 ± 0.31
6.011ThrLeu: 6.011 ± 0.292
1.223ThrMet: 1.223 ± 0.158
4.598ThrAsn: 4.598 ± 0.36
1.856ThrPro: 1.856 ± 0.235
1.055ThrGln: 1.055 ± 0.171
1.814ThrArg: 1.814 ± 0.171
4.429ThrSer: 4.429 ± 0.301
3.354ThrThr: 3.354 ± 0.283
3.67ThrVal: 3.67 ± 0.326
0.38ThrTrp: 0.38 ± 0.093
3.058ThrTyr: 3.058 ± 0.258
0.0ThrXaa: 0.0 ± 0.0
Val
1.582ValAla: 1.582 ± 0.171
1.371ValCys: 1.371 ± 0.171
3.48ValAsp: 3.48 ± 0.237
2.7ValGlu: 2.7 ± 0.22
2.848ValPhe: 2.848 ± 0.279
1.413ValGly: 1.413 ± 0.16
1.181ValHis: 1.181 ± 0.159
5.358ValIle: 5.358 ± 0.306
4.978ValLys: 4.978 ± 0.339
4.809ValLeu: 4.809 ± 0.278
1.118ValMet: 1.118 ± 0.13
5.168ValAsn: 5.168 ± 0.306
1.561ValPro: 1.561 ± 0.183
0.802ValGln: 0.802 ± 0.158
1.561ValArg: 1.561 ± 0.155
4.472ValSer: 4.472 ± 0.364
3.037ValThr: 3.037 ± 0.255
2.89ValVal: 2.89 ± 0.275
0.337ValTrp: 0.337 ± 0.075
3.396ValTyr: 3.396 ± 0.348
0.0ValXaa: 0.0 ± 0.0
Trp
0.148TrpAla: 0.148 ± 0.055
0.148TrpCys: 0.148 ± 0.057
0.295TrpAsp: 0.295 ± 0.09
0.316TrpGlu: 0.316 ± 0.07
0.443TrpPhe: 0.443 ± 0.106
0.316TrpGly: 0.316 ± 0.09
0.021TrpHis: 0.021 ± 0.018
0.612TrpIle: 0.612 ± 0.127
0.633TrpLys: 0.633 ± 0.12
0.485TrpLeu: 0.485 ± 0.116
0.148TrpMet: 0.148 ± 0.059
0.464TrpAsn: 0.464 ± 0.1
0.169TrpPro: 0.169 ± 0.06
0.063TrpGln: 0.063 ± 0.036
0.169TrpArg: 0.169 ± 0.06
0.612TrpSer: 0.612 ± 0.115
0.295TrpThr: 0.295 ± 0.079
0.359TrpVal: 0.359 ± 0.072
0.0TrpTrp: 0.0 ± 0.0
0.38TrpTyr: 0.38 ± 0.088
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.329TyrAla: 1.329 ± 0.146
1.244TyrCys: 1.244 ± 0.159
3.67TyrAsp: 3.67 ± 0.224
2.426TyrGlu: 2.426 ± 0.192
3.08TyrPhe: 3.08 ± 0.257
2.7TyrGly: 2.7 ± 0.216
0.844TyrHis: 0.844 ± 0.122
8.226TyrIle: 8.226 ± 0.474
4.725TyrLys: 4.725 ± 0.304
5.315TyrLeu: 5.315 ± 0.422
1.666TyrMet: 1.666 ± 0.191
6.265TyrAsn: 6.265 ± 0.399
2.004TyrPro: 2.004 ± 0.164
0.886TyrGln: 0.886 ± 0.137
1.434TyrArg: 1.434 ± 0.174
4.261TyrSer: 4.261 ± 0.296
3.544TyrThr: 3.544 ± 0.249
2.974TyrVal: 2.974 ± 0.24
0.337TyrTrp: 0.337 ± 0.088
3.08TyrTyr: 3.08 ± 0.273
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 209 proteins (47411 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski