Amino acid dipepetide frequency for Murine minute virus (strain MVM prototype) (MVM) (Murine minute virus (strain MVM(p)))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.367AlaAla: 5.367 ± 1.575
2.3AlaCys: 2.3 ± 0.595
2.556AlaAsp: 2.556 ± 1.114
5.878AlaGlu: 5.878 ± 1.777
2.044AlaPhe: 2.044 ± 0.333
4.6AlaGly: 4.6 ± 0.415
0.767AlaHis: 0.767 ± 0.33
3.067AlaIle: 3.067 ± 0.447
4.089AlaLys: 4.089 ± 1.333
2.556AlaLeu: 2.556 ± 0.422
0.0AlaMet: 0.0 ± 0.0
4.344AlaAsn: 4.344 ± 1.415
4.6AlaPro: 4.6 ± 1.861
4.6AlaGln: 4.6 ± 0.969
2.811AlaArg: 2.811 ± 0.43
5.111AlaSer: 5.111 ± 0.493
4.6AlaThr: 4.6 ± 1.066
2.044AlaVal: 2.044 ± 0.443
1.533AlaTrp: 1.533 ± 0.256
2.3AlaTyr: 2.3 ± 0.623
0.0AlaXaa: 0.0 ± 0.0
Cys
1.022CysAla: 1.022 ± 0.568
1.278CysCys: 1.278 ± 0.568
0.0CysAsp: 0.0 ± 0.0
0.511CysGlu: 0.511 ± 0.284
0.511CysPhe: 0.511 ± 0.284
1.533CysGly: 1.533 ± 1.081
1.022CysHis: 1.022 ± 0.568
0.767CysIle: 0.767 ± 0.541
0.767CysLys: 0.767 ± 0.33
0.511CysLeu: 0.511 ± 0.284
0.767CysMet: 0.767 ± 0.33
1.278CysAsn: 1.278 ± 0.171
0.0CysPro: 0.0 ± 0.0
1.278CysGln: 1.278 ± 0.171
2.044CysArg: 2.044 ± 0.383
0.511CysSer: 0.511 ± 0.284
1.789CysThr: 1.789 ± 0.717
1.789CysVal: 1.789 ± 0.333
0.0CysTrp: 0.0 ± 0.0
0.511CysTyr: 0.511 ± 0.284
0.0CysXaa: 0.0 ± 0.0
Asp
3.067AspAla: 3.067 ± 1.137
0.511AspCys: 0.511 ± 0.284
1.278AspAsp: 1.278 ± 0.171
5.622AspGlu: 5.622 ± 1.213
2.3AspPhe: 2.3 ± 0.595
4.6AspGly: 4.6 ± 0.831
0.0AspHis: 0.0 ± 0.0
2.811AspIle: 2.811 ± 0.434
2.044AspLys: 2.044 ± 0.443
5.111AspLeu: 5.111 ± 0.685
2.044AspMet: 2.044 ± 0.913
2.044AspAsn: 2.044 ± 0.443
0.767AspPro: 0.767 ± 0.33
4.856AspGln: 4.856 ± 0.776
2.044AspArg: 2.044 ± 0.383
3.322AspSer: 3.322 ± 0.452
4.344AspThr: 4.344 ± 0.961
0.511AspVal: 0.511 ± 0.284
2.044AspTrp: 2.044 ± 0.333
0.511AspTyr: 0.511 ± 0.284
0.0AspXaa: 0.0 ± 0.0
Glu
4.344GluAla: 4.344 ± 0.993
0.0GluCys: 0.0 ± 0.0
5.367GluAsp: 5.367 ± 1.539
2.3GluGlu: 2.3 ± 0.932
0.767GluPhe: 0.767 ± 0.33
1.278GluGly: 1.278 ± 0.171
3.833GluHis: 3.833 ± 0.887
3.578GluIle: 3.578 ± 0.499
2.556GluLys: 2.556 ± 1.137
5.367GluLeu: 5.367 ± 1.983
1.789GluMet: 1.789 ± 0.717
5.878GluAsn: 5.878 ± 0.248
3.833GluPro: 3.833 ± 1.245
1.789GluGln: 1.789 ± 0.64
3.833GluArg: 3.833 ± 0.304
1.022GluSer: 1.022 ± 0.602
6.645GluThr: 6.645 ± 1.453
3.578GluVal: 3.578 ± 1.435
2.811GluTrp: 2.811 ± 1.176
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.3PheAla: 2.3 ± 0.572
1.533PheCys: 1.533 ± 0.66
1.789PheAsp: 1.789 ± 0.333
2.044PheGlu: 2.044 ± 0.383
2.044PhePhe: 2.044 ± 0.666
3.578PheGly: 3.578 ± 0.852
1.278PheHis: 1.278 ± 0.731
1.789PheIle: 1.789 ± 0.524
2.044PheLys: 2.044 ± 0.863
2.3PheLeu: 2.3 ± 0.595
0.511PheMet: 0.511 ± 0.463
2.3PheAsn: 2.3 ± 0.545
1.789PhePro: 1.789 ± 0.333
0.767PheGln: 0.767 ± 0.541
1.022PheArg: 1.022 ± 0.545
4.6PheSer: 4.6 ± 0.415
1.278PheThr: 1.278 ± 0.171
2.556PheVal: 2.556 ± 0.422
0.767PheTrp: 0.767 ± 0.33
1.022PheTyr: 1.022 ± 0.481
0.0PheXaa: 0.0 ± 0.0
Gly
4.6GlyAla: 4.6 ± 1.389
1.022GlyCys: 1.022 ± 0.568
2.556GlyAsp: 2.556 ± 0.343
2.556GlyGlu: 2.556 ± 0.539
3.833GlyPhe: 3.833 ± 1.183
9.2GlyGly: 9.2 ± 1.586
1.022GlyHis: 1.022 ± 0.545
1.022GlyIle: 1.022 ± 0.393
7.411GlyLys: 7.411 ± 1.441
1.533GlyLeu: 1.533 ± 0.687
0.767GlyMet: 0.767 ± 0.33
6.133GlyAsn: 6.133 ± 0.287
5.367GlyPro: 5.367 ± 1.378
4.6GlyGln: 4.6 ± 0.739
1.278GlyArg: 1.278 ± 0.171
8.178GlySer: 8.178 ± 0.857
8.689GlyThr: 8.689 ± 2.302
4.089GlyVal: 4.089 ± 1.766
4.344GlyTrp: 4.344 ± 0.907
1.533GlyTyr: 1.533 ± 0.602
0.0GlyXaa: 0.0 ± 0.0
His
0.511HisAla: 0.511 ± 0.284
1.278HisCys: 1.278 ± 0.568
1.022HisAsp: 1.022 ± 0.545
1.278HisGlu: 1.278 ± 0.171
0.767HisPhe: 0.767 ± 0.33
3.322HisGly: 3.322 ± 0.584
0.0HisHis: 0.0 ± 0.0
0.767HisIle: 0.767 ± 0.33
1.789HisLys: 1.789 ± 0.333
1.789HisLeu: 1.789 ± 0.333
0.0HisMet: 0.0 ± 0.0
2.3HisAsn: 2.3 ± 0.99
0.767HisPro: 0.767 ± 0.33
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.022HisSer: 1.022 ± 0.255
2.556HisThr: 2.556 ± 0.422
0.511HisVal: 0.511 ± 0.284
0.767HisTrp: 0.767 ± 0.541
1.022HisTyr: 1.022 ± 0.486
0.0HisXaa: 0.0 ± 0.0
Ile
2.811IleAla: 2.811 ± 0.871
2.811IleCys: 2.811 ± 0.871
0.767IleAsp: 0.767 ± 0.277
2.3IleGlu: 2.3 ± 0.595
2.556IlePhe: 2.556 ± 0.539
3.833IleGly: 3.833 ± 0.986
2.044IleHis: 2.044 ± 0.383
0.511IleIle: 0.511 ± 0.284
2.044IleLys: 2.044 ± 0.333
2.044IleLeu: 2.044 ± 0.443
0.511IleMet: 0.511 ± 0.284
1.022IleAsn: 1.022 ± 0.366
0.0IlePro: 0.0 ± 0.0
1.278IleGln: 1.278 ± 0.171
2.556IleArg: 2.556 ± 0.343
0.767IleSer: 0.767 ± 0.462
4.856IleThr: 4.856 ± 1.399
0.767IleVal: 0.767 ± 0.33
2.044IleTrp: 2.044 ± 0.443
0.767IleTyr: 0.767 ± 0.33
0.0IleXaa: 0.0 ± 0.0
Lys
1.533LysAla: 1.533 ± 0.852
1.022LysCys: 1.022 ± 0.568
5.367LysAsp: 5.367 ± 0.636
6.133LysGlu: 6.133 ± 1.017
0.767LysPhe: 0.767 ± 0.541
3.578LysGly: 3.578 ± 0.591
0.511LysHis: 0.511 ± 0.284
1.278LysIle: 1.278 ± 0.171
6.133LysLys: 6.133 ± 2.129
4.344LysLeu: 4.344 ± 0.725
0.0LysMet: 0.0 ± 0.0
5.622LysAsn: 5.622 ± 0.957
1.533LysPro: 1.533 ± 0.66
2.556LysGln: 2.556 ± 0.742
3.322LysArg: 3.322 ± 1.167
4.856LysSer: 4.856 ± 1.143
2.3LysThr: 2.3 ± 0.595
2.811LysVal: 2.811 ± 0.664
2.044LysTrp: 2.044 ± 0.477
1.789LysTyr: 1.789 ± 1.058
0.0LysXaa: 0.0 ± 0.0
Leu
2.556LeuAla: 2.556 ± 0.539
0.767LeuCys: 0.767 ± 0.541
2.3LeuAsp: 2.3 ± 0.572
3.578LeuGlu: 3.578 ± 0.852
2.044LeuPhe: 2.044 ± 1.047
6.9LeuGly: 6.9 ± 1.22
0.767LeuHis: 0.767 ± 0.33
2.3LeuIle: 2.3 ± 0.595
5.622LeuLys: 5.622 ± 1.685
3.322LeuLeu: 3.322 ± 0.548
0.0LeuMet: 0.0 ± 0.0
6.389LeuAsn: 6.389 ± 0.936
3.322LeuPro: 3.322 ± 0.244
4.344LeuGln: 4.344 ± 1.626
4.344LeuArg: 4.344 ± 0.844
3.833LeuSer: 3.833 ± 0.514
10.222LeuThr: 10.222 ± 0.668
7.922LeuVal: 7.922 ± 0.49
0.0LeuTrp: 0.0 ± 0.0
0.767LeuTyr: 0.767 ± 0.277
0.0LeuXaa: 0.0 ± 0.0
Met
3.578MetAla: 3.578 ± 0.617
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.044MetGlu: 2.044 ± 0.383
0.256MetPhe: 0.256 ± 0.352
1.533MetGly: 1.533 ± 0.66
0.0MetHis: 0.0 ± 0.0
1.278MetIle: 1.278 ± 0.731
0.0MetLys: 0.0 ± 0.0
1.278MetLeu: 1.278 ± 0.171
2.3MetMet: 2.3 ± 0.595
0.767MetAsn: 0.767 ± 0.33
0.767MetPro: 0.767 ± 0.33
1.278MetGln: 1.278 ± 0.171
1.278MetArg: 1.278 ± 0.171
2.3MetSer: 2.3 ± 0.99
1.789MetThr: 1.789 ± 0.717
1.022MetVal: 1.022 ± 0.393
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.856AsnAla: 4.856 ± 0.689
0.0AsnCys: 0.0 ± 0.0
2.811AsnAsp: 2.811 ± 0.762
2.811AsnGlu: 2.811 ± 1.176
2.044AsnPhe: 2.044 ± 1.136
4.856AsnGly: 4.856 ± 0.689
0.0AsnHis: 0.0 ± 0.0
2.3AsnIle: 2.3 ± 0.595
0.511AsnLys: 0.511 ± 0.284
4.344AsnLeu: 4.344 ± 0.535
2.811AsnMet: 2.811 ± 0.762
2.3AsnAsn: 2.3 ± 0.99
2.811AsnPro: 2.811 ± 0.936
4.089AsnGln: 4.089 ± 0.4
1.278AsnArg: 1.278 ± 0.171
6.133AsnSer: 6.133 ± 1.43
6.389AsnThr: 6.389 ± 0.857
5.878AsnVal: 5.878 ± 0.572
3.833AsnTrp: 3.833 ± 0.304
2.044AsnTyr: 2.044 ± 0.441
0.0AsnXaa: 0.0 ± 0.0
Pro
4.856ProAla: 4.856 ± 1.106
0.0ProCys: 0.0 ± 0.0
2.3ProAsp: 2.3 ± 0.595
5.111ProGlu: 5.111 ± 1.089
2.556ProPhe: 2.556 ± 0.343
4.856ProGly: 4.856 ± 0.585
0.767ProHis: 0.767 ± 0.33
1.789ProIle: 1.789 ± 0.333
3.578ProLys: 3.578 ± 0.69
5.878ProLeu: 5.878 ± 0.899
0.767ProMet: 0.767 ± 0.369
2.811ProAsn: 2.811 ± 0.434
3.833ProPro: 3.833 ± 1.2
0.767ProGln: 0.767 ± 0.33
2.044ProArg: 2.044 ± 0.383
1.789ProSer: 1.789 ± 0.794
3.322ProThr: 3.322 ± 0.452
3.322ProVal: 3.322 ± 0.584
2.044ProTrp: 2.044 ± 0.443
1.789ProTyr: 1.789 ± 0.794
0.0ProXaa: 0.0 ± 0.0
Gln
2.556GlnAla: 2.556 ± 0.539
0.0GlnCys: 0.0 ± 0.0
1.278GlnAsp: 1.278 ± 0.171
4.6GlnGlu: 4.6 ± 0.754
1.278GlnPhe: 1.278 ± 0.171
4.344GlnGly: 4.344 ± 0.541
1.278GlnHis: 1.278 ± 0.171
2.811GlnIle: 2.811 ± 0.762
0.767GlnLys: 0.767 ± 0.462
4.856GlnLeu: 4.856 ± 0.887
1.533GlnMet: 1.533 ± 0.66
1.022GlnAsn: 1.022 ± 0.568
5.622GlnPro: 5.622 ± 0.481
1.533GlnGln: 1.533 ± 0.305
2.3GlnArg: 2.3 ± 1.018
4.344GlnSer: 4.344 ± 0.738
3.578GlnThr: 3.578 ± 0.572
2.811GlnVal: 2.811 ± 0.27
0.0GlnTrp: 0.0 ± 0.0
1.789GlnTyr: 1.789 ± 0.794
0.0GlnXaa: 0.0 ± 0.0
Arg
6.389ArgAla: 6.389 ± 1.584
0.767ArgCys: 0.767 ± 0.541
3.833ArgAsp: 3.833 ± 0.462
0.767ArgGlu: 0.767 ± 0.374
1.022ArgPhe: 1.022 ± 0.486
3.833ArgGly: 3.833 ± 1.626
1.278ArgHis: 1.278 ± 0.171
4.089ArgIle: 4.089 ± 0.921
0.256ArgLys: 0.256 ± 0.23
3.322ArgLeu: 3.322 ± 1.008
0.511ArgMet: 0.511 ± 0.284
2.044ArgAsn: 2.044 ± 0.383
3.322ArgPro: 3.322 ± 0.477
1.789ArgGln: 1.789 ± 0.333
0.511ArgArg: 0.511 ± 0.284
0.511ArgSer: 0.511 ± 0.284
3.067ArgThr: 3.067 ± 0.609
2.044ArgVal: 2.044 ± 0.443
1.278ArgTrp: 1.278 ± 0.568
2.556ArgTyr: 2.556 ± 0.993
0.0ArgXaa: 0.0 ± 0.0
Ser
3.322SerAla: 3.322 ± 1.047
0.767SerCys: 0.767 ± 0.541
4.089SerAsp: 4.089 ± 0.204
4.6SerGlu: 4.6 ± 0.415
2.044SerPhe: 2.044 ± 0.383
5.111SerGly: 5.111 ± 0.939
1.533SerHis: 1.533 ± 0.66
1.022SerIle: 1.022 ± 0.568
2.044SerLys: 2.044 ± 1.136
5.111SerLeu: 5.111 ± 0.743
1.022SerMet: 1.022 ± 0.389
3.067SerAsn: 3.067 ± 0.381
3.578SerPro: 3.578 ± 0.666
4.344SerGln: 4.344 ± 0.489
4.089SerArg: 4.089 ± 0.637
1.278SerSer: 1.278 ± 0.476
5.622SerThr: 5.622 ± 1.009
5.878SerVal: 5.878 ± 1.597
1.022SerTrp: 1.022 ± 0.743
5.367SerTyr: 5.367 ± 0.433
0.0SerXaa: 0.0 ± 0.0
Thr
6.645ThrAla: 6.645 ± 1.169
1.278ThrCys: 1.278 ± 0.568
3.067ThrAsp: 3.067 ± 0.882
2.3ThrGlu: 2.3 ± 1.014
1.533ThrPhe: 1.533 ± 0.66
4.089ThrGly: 4.089 ± 0.885
2.044ThrHis: 2.044 ± 0.443
2.811ThrIle: 2.811 ± 0.434
8.433ThrLys: 8.433 ± 1.15
6.9ThrLeu: 6.9 ± 0.541
2.556ThrMet: 2.556 ± 0.469
6.645ThrAsn: 6.645 ± 0.589
6.389ThrPro: 6.389 ± 1.515
3.322ThrGln: 3.322 ± 0.584
3.322ThrArg: 3.322 ± 0.816
4.344ThrSer: 4.344 ± 0.725
7.411ThrThr: 7.411 ± 1.134
5.622ThrVal: 5.622 ± 1.009
4.6ThrTrp: 4.6 ± 0.686
3.833ThrTyr: 3.833 ± 0.964
0.0ThrXaa: 0.0 ± 0.0
Val
2.044ValAla: 2.044 ± 0.443
1.278ValCys: 1.278 ± 0.171
4.856ValAsp: 4.856 ± 0.689
4.089ValGlu: 4.089 ± 0.398
3.833ValPhe: 3.833 ± 0.986
3.322ValGly: 3.322 ± 0.499
2.811ValHis: 2.811 ± 0.762
0.511ValIle: 0.511 ± 0.284
3.067ValLys: 3.067 ± 0.447
5.367ValLeu: 5.367 ± 1.539
1.022ValMet: 1.022 ± 0.379
2.3ValAsn: 2.3 ± 0.595
3.833ValPro: 3.833 ± 0.595
2.3ValGln: 2.3 ± 0.932
2.811ValArg: 2.811 ± 0.434
4.6ValSer: 4.6 ± 0.876
5.367ValThr: 5.367 ± 0.676
2.044ValVal: 2.044 ± 0.443
0.767ValTrp: 0.767 ± 0.33
2.3ValTyr: 2.3 ± 0.368
0.0ValXaa: 0.0 ± 0.0
Trp
1.533TrpAla: 1.533 ± 0.256
0.0TrpCys: 0.0 ± 0.0
2.811TrpAsp: 2.811 ± 0.434
1.278TrpGlu: 1.278 ± 0.568
2.044TrpPhe: 2.044 ± 1.007
3.067TrpGly: 3.067 ± 0.47
0.511TrpHis: 0.511 ± 0.284
0.0TrpIle: 0.0 ± 0.0
2.044TrpLys: 2.044 ± 0.443
4.344TrpLeu: 4.344 ± 0.596
0.511TrpMet: 0.511 ± 0.284
2.556TrpAsn: 2.556 ± 0.422
0.511TrpPro: 0.511 ± 0.284
1.533TrpGln: 1.533 ± 0.66
0.511TrpArg: 0.511 ± 0.284
3.578TrpSer: 3.578 ± 0.852
0.767TrpThr: 0.767 ± 0.33
2.811TrpVal: 2.811 ± 0.43
0.767TrpTrp: 0.767 ± 0.39
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.278TyrAla: 1.278 ± 0.568
1.278TyrCys: 1.278 ± 0.171
2.044TyrAsp: 2.044 ± 0.807
0.767TyrGlu: 0.767 ± 0.33
3.067TyrPhe: 3.067 ± 0.609
2.3TyrGly: 2.3 ± 0.99
0.0TyrHis: 0.0 ± 0.0
1.789TyrIle: 1.789 ± 0.524
2.3TyrLys: 2.3 ± 0.759
1.022TyrLeu: 1.022 ± 0.531
1.789TyrMet: 1.789 ± 0.67
1.278TyrAsn: 1.278 ± 0.171
1.533TyrPro: 1.533 ± 0.66
1.278TyrGln: 1.278 ± 0.171
1.789TyrArg: 1.789 ± 0.746
2.811TyrSer: 2.811 ± 0.921
2.556TyrThr: 2.556 ± 0.343
0.511TyrVal: 0.511 ± 0.284
0.511TyrTrp: 0.511 ± 0.284
2.044TyrTyr: 2.044 ± 0.443
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (3914 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski