Amino acid dipepetide frequency for Trichechus manatus latirostris papillomavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.202AlaAla: 6.202 ± 0.882
1.938AlaCys: 1.938 ± 0.749
5.039AlaAsp: 5.039 ± 1.052
6.977AlaGlu: 6.977 ± 1.663
2.326AlaPhe: 2.326 ± 0.644
3.876AlaGly: 3.876 ± 1.038
1.163AlaHis: 1.163 ± 0.631
2.326AlaIle: 2.326 ± 1.1
3.876AlaLys: 3.876 ± 0.745
8.14AlaLeu: 8.14 ± 1.797
0.388AlaMet: 0.388 ± 0.33
4.264AlaAsn: 4.264 ± 1.451
3.876AlaPro: 3.876 ± 1.274
2.713AlaGln: 2.713 ± 0.781
5.426AlaArg: 5.426 ± 0.966
3.101AlaSer: 3.101 ± 0.584
9.302AlaThr: 9.302 ± 1.665
2.713AlaVal: 2.713 ± 0.926
1.163AlaTrp: 1.163 ± 0.413
2.326AlaTyr: 2.326 ± 0.851
0.0AlaXaa: 0.0 ± 0.0
Cys
1.938CysAla: 1.938 ± 1.132
0.0CysCys: 0.0 ± 0.0
0.388CysAsp: 0.388 ± 0.345
0.388CysGlu: 0.388 ± 0.473
1.55CysPhe: 1.55 ± 1.018
3.488CysGly: 3.488 ± 1.841
0.0CysHis: 0.0 ± 0.0
1.938CysIle: 1.938 ± 0.794
1.163CysLys: 1.163 ± 0.466
0.775CysLeu: 0.775 ± 0.375
1.163CysMet: 1.163 ± 0.52
0.0CysAsn: 0.0 ± 0.0
1.938CysPro: 1.938 ± 0.488
1.163CysGln: 1.163 ± 0.965
2.713CysArg: 2.713 ± 1.352
1.163CysSer: 1.163 ± 0.515
1.163CysThr: 1.163 ± 0.666
1.163CysVal: 1.163 ± 0.721
1.163CysTrp: 1.163 ± 0.413
1.163CysTyr: 1.163 ± 0.541
0.0CysXaa: 0.0 ± 0.0
Asp
2.326AspAla: 2.326 ± 1.085
0.775AspCys: 0.775 ± 0.375
2.326AspAsp: 2.326 ± 1.194
4.651AspGlu: 4.651 ± 1.822
2.326AspPhe: 2.326 ± 0.439
3.101AspGly: 3.101 ± 0.794
1.163AspHis: 1.163 ± 0.694
2.713AspIle: 2.713 ± 1.429
0.775AspLys: 0.775 ± 0.471
7.752AspLeu: 7.752 ± 1.603
1.163AspMet: 1.163 ± 0.694
3.876AspAsn: 3.876 ± 1.896
3.488AspPro: 3.488 ± 1.661
0.775AspGln: 0.775 ± 0.365
3.488AspArg: 3.488 ± 0.71
3.876AspSer: 3.876 ± 1.335
5.814AspThr: 5.814 ± 0.975
5.814AspVal: 5.814 ± 1.655
1.55AspTrp: 1.55 ± 0.904
2.326AspTyr: 2.326 ± 0.662
0.0AspXaa: 0.0 ± 0.0
Glu
3.488GluAla: 3.488 ± 1.189
1.938GluCys: 1.938 ± 0.862
6.202GluAsp: 6.202 ± 1.324
4.651GluGlu: 4.651 ± 0.98
2.326GluPhe: 2.326 ± 0.879
6.589GluGly: 6.589 ± 2.257
0.775GluHis: 0.775 ± 0.715
1.163GluIle: 1.163 ± 0.838
2.326GluLys: 2.326 ± 0.973
4.651GluLeu: 4.651 ± 1.062
0.775GluMet: 0.775 ± 0.375
1.938GluAsn: 1.938 ± 0.681
2.326GluPro: 2.326 ± 0.937
3.488GluGln: 3.488 ± 1.249
3.488GluArg: 3.488 ± 1.641
3.488GluSer: 3.488 ± 2.323
6.202GluThr: 6.202 ± 0.554
3.488GluVal: 3.488 ± 1.122
0.775GluTrp: 0.775 ± 0.471
1.163GluTyr: 1.163 ± 0.466
0.0GluXaa: 0.0 ± 0.0
Phe
1.163PheAla: 1.163 ± 0.629
0.388PheCys: 0.388 ± 0.301
3.101PheAsp: 3.101 ± 0.94
2.326PheGlu: 2.326 ± 0.615
1.55PhePhe: 1.55 ± 0.627
1.938PheGly: 1.938 ± 0.481
1.55PheHis: 1.55 ± 1.011
1.55PheIle: 1.55 ± 0.898
2.326PheLys: 2.326 ± 1.08
2.713PheLeu: 2.713 ± 1.122
1.55PheMet: 1.55 ± 0.955
1.163PheAsn: 1.163 ± 0.623
2.326PhePro: 2.326 ± 0.348
1.938PheGln: 1.938 ± 0.754
1.163PheArg: 1.163 ± 0.885
2.326PheSer: 2.326 ± 0.41
1.163PheThr: 1.163 ± 0.56
1.55PheVal: 1.55 ± 0.573
1.938PheTrp: 1.938 ± 0.739
1.938PheTyr: 1.938 ± 1.039
0.0PheXaa: 0.0 ± 0.0
Gly
5.814GlyAla: 5.814 ± 1.63
3.101GlyCys: 3.101 ± 1.058
6.589GlyAsp: 6.589 ± 1.065
5.814GlyGlu: 5.814 ± 1.072
0.775GlyPhe: 0.775 ± 0.715
8.527GlyGly: 8.527 ± 3.181
3.101GlyHis: 3.101 ± 1.199
1.55GlyIle: 1.55 ± 0.47
2.713GlyLys: 2.713 ± 1.058
5.426GlyLeu: 5.426 ± 0.946
1.163GlyMet: 1.163 ± 0.649
2.713GlyAsn: 2.713 ± 0.701
5.426GlyPro: 5.426 ± 1.929
2.713GlyGln: 2.713 ± 0.522
4.264GlyArg: 4.264 ± 1.02
5.039GlySer: 5.039 ± 1.954
5.039GlyThr: 5.039 ± 1.194
5.814GlyVal: 5.814 ± 1.342
0.775GlyTrp: 0.775 ± 0.409
1.55GlyTyr: 1.55 ± 0.711
0.0GlyXaa: 0.0 ± 0.0
His
1.938HisAla: 1.938 ± 0.694
0.388HisCys: 0.388 ± 0.345
1.163HisAsp: 1.163 ± 1.022
1.163HisGlu: 1.163 ± 0.836
0.388HisPhe: 0.388 ± 0.341
0.775HisGly: 0.775 ± 0.947
0.775HisHis: 0.775 ± 0.531
2.326HisIle: 2.326 ± 0.91
0.388HisLys: 0.388 ± 0.301
1.938HisLeu: 1.938 ± 0.532
1.163HisMet: 1.163 ± 0.413
0.775HisAsn: 0.775 ± 0.365
1.938HisPro: 1.938 ± 0.897
1.163HisGln: 1.163 ± 0.515
1.55HisArg: 1.55 ± 0.819
0.0HisSer: 0.0 ± 0.0
1.55HisThr: 1.55 ± 1.062
1.938HisVal: 1.938 ± 0.922
0.775HisTrp: 0.775 ± 0.427
0.775HisTyr: 0.775 ± 0.689
0.0HisXaa: 0.0 ± 0.0
Ile
3.876IleAla: 3.876 ± 1.648
0.775IleCys: 0.775 ± 0.409
3.876IleAsp: 3.876 ± 1.978
2.713IleGlu: 2.713 ± 0.928
0.775IlePhe: 0.775 ± 0.689
3.876IleGly: 3.876 ± 1.805
0.388IleHis: 0.388 ± 0.301
2.713IleIle: 2.713 ± 0.875
1.163IleLys: 1.163 ± 0.536
4.651IleLeu: 4.651 ± 0.92
1.163IleMet: 1.163 ± 0.683
0.388IleAsn: 0.388 ± 0.301
3.876IlePro: 3.876 ± 1.322
0.775IleGln: 0.775 ± 0.556
4.264IleArg: 4.264 ± 0.912
3.101IleSer: 3.101 ± 1.416
1.55IleThr: 1.55 ± 0.751
1.163IleVal: 1.163 ± 0.791
0.388IleTrp: 0.388 ± 0.301
1.938IleTyr: 1.938 ± 0.897
0.0IleXaa: 0.0 ± 0.0
Lys
4.651LysAla: 4.651 ± 1.39
1.163LysCys: 1.163 ± 0.578
1.938LysAsp: 1.938 ± 0.877
2.326LysGlu: 2.326 ± 1.052
2.713LysPhe: 2.713 ± 1.23
1.938LysGly: 1.938 ± 0.733
1.163LysHis: 1.163 ± 0.902
1.55LysIle: 1.55 ± 0.962
2.326LysLys: 2.326 ± 0.813
0.775LysLeu: 0.775 ± 0.409
0.775LysMet: 0.775 ± 0.409
1.163LysAsn: 1.163 ± 0.629
0.775LysPro: 0.775 ± 0.506
1.55LysGln: 1.55 ± 0.746
4.651LysArg: 4.651 ± 0.687
1.938LysSer: 1.938 ± 1.124
1.55LysThr: 1.55 ± 0.655
2.713LysVal: 2.713 ± 0.912
1.163LysTrp: 1.163 ± 0.71
2.713LysTyr: 2.713 ± 1.119
0.0LysXaa: 0.0 ± 0.0
Leu
7.364LeuAla: 7.364 ± 1.659
3.101LeuCys: 3.101 ± 1.612
3.488LeuAsp: 3.488 ± 0.763
3.488LeuGlu: 3.488 ± 0.467
2.326LeuPhe: 2.326 ± 1.06
7.364LeuGly: 7.364 ± 1.313
2.326LeuHis: 2.326 ± 0.961
2.713LeuIle: 2.713 ± 0.96
4.651LeuLys: 4.651 ± 1.315
8.527LeuLeu: 8.527 ± 1.673
0.775LeuMet: 0.775 ± 0.396
3.101LeuAsn: 3.101 ± 0.687
6.202LeuPro: 6.202 ± 1.972
6.589LeuGln: 6.589 ± 1.099
5.814LeuArg: 5.814 ± 1.419
4.264LeuSer: 4.264 ± 1.123
6.202LeuThr: 6.202 ± 1.457
3.876LeuVal: 3.876 ± 0.923
1.163LeuTrp: 1.163 ± 0.845
1.55LeuTyr: 1.55 ± 0.618
0.0LeuXaa: 0.0 ± 0.0
Met
2.326MetAla: 2.326 ± 0.915
0.388MetCys: 0.388 ± 0.4
2.713MetAsp: 2.713 ± 0.89
1.163MetGlu: 1.163 ± 1.072
0.388MetPhe: 0.388 ± 0.345
0.775MetGly: 0.775 ± 0.471
0.388MetHis: 0.388 ± 0.473
0.0MetIle: 0.0 ± 0.0
0.775MetLys: 0.775 ± 0.506
1.55MetLeu: 1.55 ± 1.202
0.775MetMet: 0.775 ± 0.409
0.388MetAsn: 0.388 ± 0.345
0.388MetPro: 0.388 ± 0.345
1.163MetGln: 1.163 ± 0.456
0.388MetArg: 0.388 ± 0.301
1.938MetSer: 1.938 ± 0.806
1.163MetThr: 1.163 ± 0.363
1.163MetVal: 1.163 ± 0.629
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.713AsnAla: 2.713 ± 2.104
1.163AsnCys: 1.163 ± 0.469
0.775AsnAsp: 0.775 ± 0.396
2.713AsnGlu: 2.713 ± 0.494
1.163AsnPhe: 1.163 ± 0.629
0.775AsnGly: 0.775 ± 0.447
0.775AsnHis: 0.775 ± 0.396
1.55AsnIle: 1.55 ± 0.587
1.55AsnLys: 1.55 ± 0.537
1.55AsnLeu: 1.55 ± 0.463
0.388AsnMet: 0.388 ± 0.345
1.163AsnAsn: 1.163 ± 0.623
2.713AsnPro: 2.713 ± 0.876
2.713AsnGln: 2.713 ± 1.132
3.101AsnArg: 3.101 ± 1.627
3.101AsnSer: 3.101 ± 0.86
1.55AsnThr: 1.55 ± 0.73
1.55AsnVal: 1.55 ± 0.709
0.0AsnTrp: 0.0 ± 0.0
0.388AsnTyr: 0.388 ± 0.357
0.0AsnXaa: 0.0 ± 0.0
Pro
7.364ProAla: 7.364 ± 2.22
1.55ProCys: 1.55 ± 0.516
4.264ProAsp: 4.264 ± 1.261
5.426ProGlu: 5.426 ± 1.059
2.326ProPhe: 2.326 ± 1.02
2.713ProGly: 2.713 ± 1.544
0.388ProHis: 0.388 ± 0.301
3.101ProIle: 3.101 ± 1.248
1.55ProLys: 1.55 ± 0.717
6.202ProLeu: 6.202 ± 1.322
0.0ProMet: 0.0 ± 0.381
1.938ProAsn: 1.938 ± 0.979
11.628ProPro: 11.628 ± 3.286
3.488ProGln: 3.488 ± 1.731
2.713ProArg: 2.713 ± 0.563
5.814ProSer: 5.814 ± 1.558
6.977ProThr: 6.977 ± 2.086
1.938ProVal: 1.938 ± 1.009
0.0ProTrp: 0.0 ± 0.0
2.713ProTyr: 2.713 ± 0.835
0.0ProXaa: 0.0 ± 0.0
Gln
3.488GlnAla: 3.488 ± 0.877
0.775GlnCys: 0.775 ± 0.559
2.713GlnAsp: 2.713 ± 1.246
3.101GlnGlu: 3.101 ± 1.054
1.938GlnPhe: 1.938 ± 0.709
1.163GlnGly: 1.163 ± 0.774
1.163GlnHis: 1.163 ± 0.363
2.326GlnIle: 2.326 ± 0.762
0.775GlnLys: 0.775 ± 0.375
3.488GlnLeu: 3.488 ± 1.028
0.775GlnMet: 0.775 ± 0.409
1.55GlnAsn: 1.55 ± 0.904
4.264GlnPro: 4.264 ± 0.847
1.938GlnGln: 1.938 ± 0.605
2.326GlnArg: 2.326 ± 0.816
1.55GlnSer: 1.55 ± 0.554
3.101GlnThr: 3.101 ± 1.107
2.713GlnVal: 2.713 ± 0.722
0.388GlnTrp: 0.388 ± 0.301
1.938GlnTyr: 1.938 ± 0.971
0.0GlnXaa: 0.0 ± 0.0
Arg
4.651ArgAla: 4.651 ± 1.404
2.326ArgCys: 2.326 ± 1.572
2.326ArgAsp: 2.326 ± 0.509
2.713ArgGlu: 2.713 ± 1.13
0.775ArgPhe: 0.775 ± 0.365
5.426ArgGly: 5.426 ± 1.055
2.326ArgHis: 2.326 ± 0.816
2.326ArgIle: 2.326 ± 0.861
4.651ArgLys: 4.651 ± 1.509
8.527ArgLeu: 8.527 ± 1.121
1.163ArgMet: 1.163 ± 0.572
1.55ArgAsn: 1.55 ± 0.681
5.039ArgPro: 5.039 ± 1.075
1.938ArgGln: 1.938 ± 1.273
5.039ArgArg: 5.039 ± 2.003
3.488ArgSer: 3.488 ± 0.636
5.814ArgThr: 5.814 ± 1.476
4.264ArgVal: 4.264 ± 0.802
0.775ArgTrp: 0.775 ± 0.41
3.488ArgTyr: 3.488 ± 1.162
0.0ArgXaa: 0.0 ± 0.0
Ser
4.651SerAla: 4.651 ± 1.355
1.163SerCys: 1.163 ± 0.536
3.876SerAsp: 3.876 ± 1.034
4.651SerGlu: 4.651 ± 1.315
3.101SerPhe: 3.101 ± 1.287
7.364SerGly: 7.364 ± 1.586
0.775SerHis: 0.775 ± 0.396
3.488SerIle: 3.488 ± 1.416
2.326SerLys: 2.326 ± 1.052
3.876SerLeu: 3.876 ± 1.317
0.388SerMet: 0.388 ± 0.301
1.163SerAsn: 1.163 ± 0.615
1.938SerPro: 1.938 ± 0.877
1.55SerGln: 1.55 ± 0.709
5.426SerArg: 5.426 ± 1.405
3.101SerSer: 3.101 ± 1.563
5.814SerThr: 5.814 ± 2.131
4.651SerVal: 4.651 ± 0.622
0.0SerTrp: 0.0 ± 0.0
0.775SerTyr: 0.775 ± 0.715
0.0SerXaa: 0.0 ± 0.0
Thr
6.202ThrAla: 6.202 ± 2.055
1.163ThrCys: 1.163 ± 0.668
3.876ThrAsp: 3.876 ± 1.155
1.163ThrGlu: 1.163 ± 0.536
3.488ThrPhe: 3.488 ± 1.102
8.14ThrGly: 8.14 ± 1.528
1.55ThrHis: 1.55 ± 0.728
4.264ThrIle: 4.264 ± 1.063
1.163ThrLys: 1.163 ± 0.694
5.039ThrLeu: 5.039 ± 0.998
3.488ThrMet: 3.488 ± 0.808
2.326ThrAsn: 2.326 ± 1.052
6.977ThrPro: 6.977 ± 1.139
1.938ThrGln: 1.938 ± 1.023
6.202ThrArg: 6.202 ± 1.566
6.202ThrSer: 6.202 ± 2.886
3.876ThrThr: 3.876 ± 1.387
5.039ThrVal: 5.039 ± 1.582
0.775ThrTrp: 0.775 ± 0.715
1.938ThrTyr: 1.938 ± 0.656
0.0ThrXaa: 0.0 ± 0.0
Val
3.101ValAla: 3.101 ± 1.255
2.326ValCys: 2.326 ± 1.436
3.876ValAsp: 3.876 ± 1.526
3.101ValGlu: 3.101 ± 0.722
1.938ValPhe: 1.938 ± 0.87
3.101ValGly: 3.101 ± 0.867
0.775ValHis: 0.775 ± 0.427
1.938ValIle: 1.938 ± 0.665
1.938ValLys: 1.938 ± 1.182
4.264ValLeu: 4.264 ± 0.758
0.0ValMet: 0.0 ± 0.0
1.163ValAsn: 1.163 ± 0.363
4.264ValPro: 4.264 ± 0.556
2.713ValGln: 2.713 ± 0.407
3.101ValArg: 3.101 ± 1.853
6.202ValSer: 6.202 ± 1.082
3.876ValThr: 3.876 ± 1.157
5.039ValVal: 5.039 ± 1.329
1.55ValTrp: 1.55 ± 0.79
3.488ValTyr: 3.488 ± 0.738
0.0ValXaa: 0.0 ± 0.0
Trp
0.775TrpAla: 0.775 ± 0.375
0.0TrpCys: 0.0 ± 0.0
0.775TrpAsp: 0.775 ± 0.409
1.163TrpGlu: 1.163 ± 1.072
0.388TrpPhe: 0.388 ± 0.345
2.713TrpGly: 2.713 ± 0.962
0.388TrpHis: 0.388 ± 0.345
1.163TrpIle: 1.163 ± 0.615
1.163TrpLys: 1.163 ± 0.658
1.938TrpLeu: 1.938 ± 0.833
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.775TrpPro: 0.775 ± 0.471
0.0TrpGln: 0.0 ± 0.0
0.775TrpArg: 0.775 ± 0.375
0.388TrpSer: 0.388 ± 0.341
1.55TrpThr: 1.55 ± 1.121
0.388TrpVal: 0.388 ± 0.301
0.0TrpTrp: 0.0 ± 0.0
0.388TrpTyr: 0.388 ± 0.4
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.101TyrAla: 3.101 ± 0.634
0.0TyrCys: 0.0 ± 0.0
0.775TyrAsp: 0.775 ± 0.409
1.55TyrGlu: 1.55 ± 0.618
3.101TyrPhe: 3.101 ± 0.913
4.264TyrGly: 4.264 ± 1.018
1.938TyrHis: 1.938 ± 1.079
2.713TyrIle: 2.713 ± 0.978
1.938TyrLys: 1.938 ± 0.609
3.101TyrLeu: 3.101 ± 0.907
0.388TyrMet: 0.388 ± 0.301
0.775TyrAsn: 0.775 ± 0.409
2.326TyrPro: 2.326 ± 0.961
1.163TyrGln: 1.163 ± 0.413
2.713TyrArg: 2.713 ± 1.0
0.0TyrSer: 0.0 ± 0.0
1.55TyrThr: 1.55 ± 0.75
0.775TyrVal: 0.775 ± 0.409
0.388TyrTrp: 0.388 ± 0.345
1.55TyrTyr: 1.55 ± 0.655
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2581 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski