Aotus nancymaae (Ma s night monkey)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates;

Average proteome isoelectric point is 6.67

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 41725 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2K5CDM3|A0A2K5CDM3_AOTNA Oxysterol-binding protein OS=Aotus nancymaae OX=37293 GN=OSBPL7 PE=3 SV=1
FF1 pKa = 7.39DD2 pKa = 3.72TSILPICKK10 pKa = 10.0DD11 pKa = 3.14SLGWMFNRR19 pKa = 11.84LDD21 pKa = 3.63TNYY24 pKa = 11.06DD25 pKa = 3.6LLLDD29 pKa = 3.78QSEE32 pKa = 4.35LRR34 pKa = 11.84SIYY37 pKa = 10.33LDD39 pKa = 3.85KK40 pKa = 11.61NEE42 pKa = 4.06QCTKK46 pKa = 11.12AFFNSCDD53 pKa = 3.38TYY55 pKa = 11.34KK56 pKa = 11.17DD57 pKa = 3.54SLISNNEE64 pKa = 2.97WCYY67 pKa = 10.82CFQRR71 pKa = 11.84QQDD74 pKa = 4.19PPCQTEE80 pKa = 3.88LSNIQKK86 pKa = 10.0RR87 pKa = 11.84QGVKK91 pKa = 10.33KK92 pKa = 10.64LLGHH96 pKa = 6.64YY97 pKa = 9.97IPLCDD102 pKa = 3.54EE103 pKa = 4.53DD104 pKa = 5.99GYY106 pKa = 11.77YY107 pKa = 10.47KK108 pKa = 9.43PTQCHH113 pKa = 6.0GSVGQCWCVDD123 pKa = 3.2RR124 pKa = 11.84YY125 pKa = 10.94GNEE128 pKa = 3.91VMGSRR133 pKa = 11.84INGVADD139 pKa = 3.49CAIDD143 pKa = 3.84FEE145 pKa = 4.72ISGDD149 pKa = 3.62FASGDD154 pKa = 3.54FHH156 pKa = 7.2EE157 pKa = 4.85WTDD160 pKa = 5.06DD161 pKa = 3.79EE162 pKa = 6.52DD163 pKa = 6.39DD164 pKa = 4.84EE165 pKa = 6.81DD166 pKa = 7.33DD167 pKa = 4.37IMNDD171 pKa = 2.99EE172 pKa = 5.77DD173 pKa = 5.05EE174 pKa = 5.96IEE176 pKa = 5.77DD177 pKa = 4.2DD178 pKa = 6.31DD179 pKa = 5.38EE180 pKa = 7.35DD181 pKa = 5.42EE182 pKa = 6.13GDD184 pKa = 4.91DD185 pKa = 5.21DD186 pKa = 6.66DD187 pKa = 7.3GGDD190 pKa = 4.0DD191 pKa = 3.53HH192 pKa = 8.11DD193 pKa = 5.58GYY195 pKa = 10.96II196 pKa = 4.57

Molecular weight: 22.54 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2K5BVR4|A0A2K5BVR4_AOTNA Beta-defensin OS=Aotus nancymaae OX=37293 GN=DEFB126 PE=3 SV=1
MM1 pKa = 7.1RR2 pKa = 11.84AKK4 pKa = 9.12WRR6 pKa = 11.84KK7 pKa = 9.1KK8 pKa = 9.32RR9 pKa = 11.84MRR11 pKa = 11.84RR12 pKa = 11.84LKK14 pKa = 10.08RR15 pKa = 11.84KK16 pKa = 8.21RR17 pKa = 11.84RR18 pKa = 11.84KK19 pKa = 8.46MRR21 pKa = 11.84QRR23 pKa = 11.84SKK25 pKa = 11.41

Molecular weight: 3.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

20371

21354

41725

22903399

12

27111

548.9

61.24

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.87 ± 0.013

2.178 ± 0.011

4.912 ± 0.009

7.217 ± 0.013

3.616 ± 0.008

6.445 ± 0.016

2.595 ± 0.007

4.442 ± 0.011

5.909 ± 0.015

9.839 ± 0.017

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.178 ± 0.005

3.696 ± 0.008

6.141 ± 0.017

4.798 ± 0.011

5.621 ± 0.011

8.313 ± 0.015

5.33 ± 0.011

6.012 ± 0.011

1.2 ± 0.004

2.671 ± 0.006
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski