Amino acid dipepetide frequency for Lautropia mirabilis ATCC 51599

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.162AlaAla: 16.162 ± 0.198	1.159AlaCys: 1.159 ± 0.043	6.87AlaAsp: 6.87 ± 0.103	6.858AlaGlu: 6.858 ± 0.107	3.578AlaPhe: 3.578 ± 0.069	10.625AlaGly: 10.625 ± 0.134	2.657AlaHis: 2.657 ± 0.059	5.013AlaIle: 5.013 ± 0.078	2.897AlaLys: 2.897 ± 0.075	13.188AlaLeu: 13.188 ± 0.154	3.182AlaMet: 3.182 ± 0.059	2.847AlaAsn: 2.847 ± 0.068	6.054AlaPro: 6.054 ± 0.125	5.33AlaGln: 5.33 ± 0.086	9.085AlaArg: 9.085 ± 0.135	7.136AlaSer: 7.136 ± 0.104	5.917AlaThr: 5.917 ± 0.095	7.832AlaVal: 7.832 ± 0.092	1.782AlaTrp: 1.782 ± 0.046	2.237AlaTyr: 2.237 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.894CysAla: 0.894 ± 0.033	0.126CysCys: 0.126 ± 0.012	0.381CysAsp: 0.381 ± 0.021	0.381CysGlu: 0.381 ± 0.022	0.314CysPhe: 0.314 ± 0.02	0.89CysGly: 0.89 ± 0.034	0.241CysHis: 0.241 ± 0.019	0.366CysIle: 0.366 ± 0.02	0.194CysLys: 0.194 ± 0.016	0.903CysLeu: 0.903 ± 0.034	0.168CysMet: 0.168 ± 0.015	0.23CysAsn: 0.23 ± 0.018	0.529CysPro: 0.529 ± 0.027	0.328CysGln: 0.328 ± 0.018	0.67CysArg: 0.67 ± 0.027	0.459CysSer: 0.459 ± 0.023	0.506CysThr: 0.506 ± 0.026	0.613CysVal: 0.613 ± 0.029	0.15CysTrp: 0.15 ± 0.014	0.194CysTyr: 0.194 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.105AspAla: 7.105 ± 0.108	0.413AspCys: 0.413 ± 0.023	3.34AspAsp: 3.34 ± 0.093	3.633AspGlu: 3.633 ± 0.081	1.943AspPhe: 1.943 ± 0.045	4.913AspGly: 4.913 ± 0.09	1.233AspHis: 1.233 ± 0.048	2.654AspIle: 2.654 ± 0.059	1.525AspLys: 1.525 ± 0.052	4.999AspLeu: 4.999 ± 0.078	1.283AspMet: 1.283 ± 0.037	1.33AspAsn: 1.33 ± 0.047	3.346AspPro: 3.346 ± 0.059	1.85AspGln: 1.85 ± 0.046	3.823AspArg: 3.823 ± 0.078	2.649AspSer: 2.649 ± 0.055	2.971AspThr: 2.971 ± 0.061	3.909AspVal: 3.909 ± 0.067	0.954AspTrp: 0.954 ± 0.03	1.401AspTyr: 1.401 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	6.841GluAla: 6.841 ± 0.107	0.317GluCys: 0.317 ± 0.019	2.619GluAsp: 2.619 ± 0.064	2.799GluGlu: 2.799 ± 0.068	1.445GluPhe: 1.445 ± 0.048	4.245GluGly: 4.245 ± 0.079	1.371GluHis: 1.371 ± 0.038	2.675GluIle: 2.675 ± 0.057	2.081GluLys: 2.081 ± 0.061	5.077GluLeu: 5.077 ± 0.084	1.255GluMet: 1.255 ± 0.04	1.505GluAsn: 1.505 ± 0.046	2.547GluPro: 2.547 ± 0.055	2.568GluGln: 2.568 ± 0.057	4.618GluArg: 4.618 ± 0.092	2.838GluSer: 2.838 ± 0.05	2.797GluThr: 2.797 ± 0.054	3.87GluVal: 3.87 ± 0.074	0.615GluTrp: 0.615 ± 0.029	1.102GluTyr: 1.102 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.301PheAla: 3.301 ± 0.058	0.371PheCys: 0.371 ± 0.021	2.202PheAsp: 2.202 ± 0.052	1.824PheGlu: 1.824 ± 0.046	1.273PhePhe: 1.273 ± 0.044	3.069PheGly: 3.069 ± 0.068	0.742PheHis: 0.742 ± 0.03	1.526PheIle: 1.526 ± 0.042	0.912PheLys: 0.912 ± 0.036	3.024PheLeu: 3.024 ± 0.071	0.811PheMet: 0.811 ± 0.03	1.083PheAsn: 1.083 ± 0.035	1.482PhePro: 1.482 ± 0.041	1.16PheGln: 1.16 ± 0.035	2.118PheArg: 2.118 ± 0.046	2.196PheSer: 2.196 ± 0.051	1.64PheThr: 1.64 ± 0.04	2.424PheVal: 2.424 ± 0.059	0.534PheTrp: 0.534 ± 0.024	0.77PheTyr: 0.77 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	8.549GlyAla: 8.549 ± 0.129	0.868GlyCys: 0.868 ± 0.035	3.838GlyAsp: 3.838 ± 0.064	4.227GlyGlu: 4.227 ± 0.072	2.971GlyPhe: 2.971 ± 0.058	6.663GlyGly: 6.663 ± 0.107	2.155GlyHis: 2.155 ± 0.058	4.18GlyIle: 4.18 ± 0.072	3.486GlyLys: 3.486 ± 0.073	8.475GlyLeu: 8.475 ± 0.107	2.472GlyMet: 2.472 ± 0.053	2.667GlyAsn: 2.667 ± 0.068	3.163GlyPro: 3.163 ± 0.065	4.047GlyGln: 4.047 ± 0.077	6.236GlyArg: 6.236 ± 0.113	5.105GlySer: 5.105 ± 0.103	4.808GlyThr: 4.808 ± 0.094	6.097GlyVal: 6.097 ± 0.111	1.479GlyTrp: 1.479 ± 0.046	2.115GlyTyr: 2.115 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.876HisAla: 2.876 ± 0.066	0.247HisCys: 0.247 ± 0.017	1.53HisAsp: 1.53 ± 0.048	1.244HisGlu: 1.244 ± 0.039	0.905HisPhe: 0.905 ± 0.028	2.372HisGly: 2.372 ± 0.05	0.781HisHis: 0.781 ± 0.039	0.95HisIle: 0.95 ± 0.035	0.48HisLys: 0.48 ± 0.021	2.203HisLeu: 2.203 ± 0.046	0.423HisMet: 0.423 ± 0.021	0.548HisAsn: 0.548 ± 0.026	1.675HisPro: 1.675 ± 0.045	0.963HisGln: 0.963 ± 0.038	1.657HisArg: 1.657 ± 0.051	1.034HisSer: 1.034 ± 0.032	1.075HisThr: 1.075 ± 0.038	1.505HisVal: 1.505 ± 0.039	0.435HisTrp: 0.435 ± 0.024	0.625HisTyr: 0.625 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	4.816IleAla: 4.816 ± 0.082	0.432IleCys: 0.432 ± 0.024	3.228IleAsp: 3.228 ± 0.06	3.127IleGlu: 3.127 ± 0.066	1.337IlePhe: 1.337 ± 0.045	4.128IleGly: 4.128 ± 0.068	1.067IleHis: 1.067 ± 0.039	2.08IleIle: 2.08 ± 0.052	1.256IleLys: 1.256 ± 0.046	3.86IleLeu: 3.86 ± 0.074	0.827IleMet: 0.827 ± 0.029	1.367IleAsn: 1.367 ± 0.044	2.287IlePro: 2.287 ± 0.046	1.573IleGln: 1.573 ± 0.047	3.302IleArg: 3.302 ± 0.068	2.617IleSer: 2.617 ± 0.065	2.485IleThr: 2.485 ± 0.055	3.193IleVal: 3.193 ± 0.06	0.478IleTrp: 0.478 ± 0.025	0.976IleTyr: 0.976 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	4.16LysAla: 4.16 ± 0.087	0.142LysCys: 0.142 ± 0.014	1.738LysAsp: 1.738 ± 0.057	1.5LysGlu: 1.5 ± 0.049	0.713LysPhe: 0.713 ± 0.027	2.383LysGly: 2.383 ± 0.055	0.615LysHis: 0.615 ± 0.026	1.252LysIle: 1.252 ± 0.044	1.199LysLys: 1.199 ± 0.046	3.087LysLeu: 3.087 ± 0.061	0.704LysMet: 0.704 ± 0.027	0.871LysAsn: 0.871 ± 0.033	2.073LysPro: 2.073 ± 0.062	1.268LysGln: 1.268 ± 0.042	2.218LysArg: 2.218 ± 0.054	1.584LysSer: 1.584 ± 0.044	1.718LysThr: 1.718 ± 0.044	2.361LysVal: 2.361 ± 0.064	0.319LysTrp: 0.319 ± 0.021	0.612LysTyr: 0.612 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	13.781LeuAla: 13.781 ± 0.158	0.901LeuCys: 0.901 ± 0.031	6.099LeuAsp: 6.099 ± 0.095	4.973LeuGlu: 4.973 ± 0.084	3.349LeuPhe: 3.349 ± 0.069	8.375LeuGly: 8.375 ± 0.128	2.265LeuHis: 2.265 ± 0.049	4.221LeuIle: 4.221 ± 0.085	3.787LeuLys: 3.787 ± 0.066	11.613LeuLeu: 11.613 ± 0.165	2.713LeuMet: 2.713 ± 0.067	2.629LeuAsn: 2.629 ± 0.049	6.685LeuPro: 6.685 ± 0.095	4.63LeuGln: 4.63 ± 0.085	7.044LeuArg: 7.044 ± 0.098	6.361LeuSer: 6.361 ± 0.082	5.235LeuThr: 5.235 ± 0.083	7.811LeuVal: 7.811 ± 0.112	1.292LeuTrp: 1.292 ± 0.044	2.058LeuTyr: 2.058 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	3.218MetAla: 3.218 ± 0.063	0.156MetCys: 0.156 ± 0.015	1.127MetAsp: 1.127 ± 0.043	1.013MetGlu: 1.013 ± 0.032	0.689MetPhe: 0.689 ± 0.031	1.718MetGly: 1.718 ± 0.047	0.448MetHis: 0.448 ± 0.022	1.05MetIle: 1.05 ± 0.039	1.093MetLys: 1.093 ± 0.036	2.894MetLeu: 2.894 ± 0.068	0.687MetMet: 0.687 ± 0.025	0.851MetAsn: 0.851 ± 0.03	1.676MetPro: 1.676 ± 0.047	1.189MetGln: 1.189 ± 0.039	1.657MetArg: 1.657 ± 0.047	1.684MetSer: 1.684 ± 0.045	1.505MetThr: 1.505 ± 0.045	1.757MetVal: 1.757 ± 0.048	0.17MetTrp: 0.17 ± 0.013	0.352MetTyr: 0.352 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.06AsnAla: 3.06 ± 0.061	0.208AsnCys: 0.208 ± 0.017	1.481AsnAsp: 1.481 ± 0.047	1.35AsnGlu: 1.35 ± 0.046	0.822AsnPhe: 0.822 ± 0.034	2.606AsnGly: 2.606 ± 0.07	0.59AsnHis: 0.59 ± 0.024	1.158AsnIle: 1.158 ± 0.041	0.723AsnLys: 0.723 ± 0.028	2.763AsnLeu: 2.763 ± 0.064	0.559AsnMet: 0.559 ± 0.022	0.812AsnAsn: 0.812 ± 0.036	2.105AsnPro: 2.105 ± 0.059	1.114AsnGln: 1.114 ± 0.038	2.064AsnArg: 2.064 ± 0.057	1.206AsnSer: 1.206 ± 0.04	1.537AsnThr: 1.537 ± 0.05	1.906AsnVal: 1.906 ± 0.046	0.405AsnTrp: 0.405 ± 0.02	0.68AsnTyr: 0.68 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	7.945ProAla: 7.945 ± 0.14	0.444ProCys: 0.444 ± 0.027	3.891ProAsp: 3.891 ± 0.076	3.723ProGlu: 3.723 ± 0.074	1.748ProPhe: 1.748 ± 0.044	4.899ProGly: 4.899 ± 0.079	1.232ProHis: 1.232 ± 0.044	2.048ProIle: 2.048 ± 0.044	1.444ProLys: 1.444 ± 0.044	5.399ProLeu: 5.399 ± 0.077	1.391ProMet: 1.391 ± 0.036	1.388ProAsn: 1.388 ± 0.046	2.853ProPro: 2.853 ± 0.077	2.273ProGln: 2.273 ± 0.069	3.128ProArg: 3.128 ± 0.063	3.274ProSer: 3.274 ± 0.062	2.73ProThr: 2.73 ± 0.065	4.718ProVal: 4.718 ± 0.082	0.851ProTrp: 0.851 ± 0.029	1.114ProTyr: 1.114 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	6.291GlnAla: 6.291 ± 0.1	0.292GlnCys: 0.292 ± 0.02	2.11GlnAsp: 2.11 ± 0.054	1.933GlnGlu: 1.933 ± 0.053	1.065GlnPhe: 1.065 ± 0.031	3.654GlnGly: 3.654 ± 0.077	1.042GlnHis: 1.042 ± 0.041	1.779GlnIle: 1.779 ± 0.04	1.372GlnLys: 1.372 ± 0.039	4.24GlnLeu: 4.24 ± 0.072	1.078GlnMet: 1.078 ± 0.038	1.043GlnAsn: 1.043 ± 0.033	2.985GlnPro: 2.985 ± 0.072	2.374GlnGln: 2.374 ± 0.06	3.412GlnArg: 3.412 ± 0.077	2.032GlnSer: 2.032 ± 0.052	2.234GlnThr: 2.234 ± 0.055	3.289GlnVal: 3.289 ± 0.065	0.682GlnTrp: 0.682 ± 0.027	0.881GlnTyr: 0.881 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	7.116ArgAla: 7.116 ± 0.099	0.551ArgCys: 0.551 ± 0.025	3.479ArgAsp: 3.479 ± 0.062	4.054ArgGlu: 4.054 ± 0.076	2.913ArgPhe: 2.913 ± 0.06	4.513ArgGly: 4.513 ± 0.08	2.167ArgHis: 2.167 ± 0.056	3.853ArgIle: 3.853 ± 0.072	2.24ArgLys: 2.24 ± 0.05	8.652ArgLeu: 8.652 ± 0.127	2.061ArgMet: 2.061 ± 0.046	2.122ArgAsn: 2.122 ± 0.051	4.014ArgPro: 4.014 ± 0.075	3.948ArgGln: 3.948 ± 0.079	5.81ArgArg: 5.81 ± 0.12	3.571ArgSer: 3.571 ± 0.065	3.536ArgThr: 3.536 ± 0.072	4.765ArgVal: 4.765 ± 0.078	1.238ArgTrp: 1.238 ± 0.042	1.955ArgTyr: 1.955 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	6.647SerAla: 6.647 ± 0.091	0.455SerCys: 0.455 ± 0.025	2.729SerAsp: 2.729 ± 0.047	2.4SerGlu: 2.4 ± 0.052	1.972SerPhe: 1.972 ± 0.046	5.573SerGly: 5.573 ± 0.114	1.298SerHis: 1.298 ± 0.036	2.563SerIle: 2.563 ± 0.054	1.466SerLys: 1.466 ± 0.045	6.095SerLeu: 6.095 ± 0.101	1.421SerMet: 1.421 ± 0.043	1.55SerAsn: 1.55 ± 0.052	3.289SerPro: 3.289 ± 0.069	2.161SerGln: 2.161 ± 0.051	4.019SerArg: 4.019 ± 0.071	3.61SerSer: 3.61 ± 0.091	3.091SerThr: 3.091 ± 0.07	3.978SerVal: 3.978 ± 0.069	0.822SerTrp: 0.822 ± 0.034	1.172SerTyr: 1.172 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.886ThrAla: 5.886 ± 0.101	0.44ThrCys: 0.44 ± 0.022	2.798ThrAsp: 2.798 ± 0.069	2.645ThrGlu: 2.645 ± 0.061	1.591ThrPhe: 1.591 ± 0.047	4.786ThrGly: 4.786 ± 0.1	1.201ThrHis: 1.201 ± 0.034	2.241ThrIle: 2.241 ± 0.06	1.14ThrLys: 1.14 ± 0.037	6.544ThrLeu: 6.544 ± 0.107	1.123ThrMet: 1.123 ± 0.036	1.259ThrAsn: 1.259 ± 0.043	3.756ThrPro: 3.756 ± 0.078	1.916ThrGln: 1.916 ± 0.044	3.599ThrArg: 3.599 ± 0.073	2.677ThrSer: 2.677 ± 0.071	2.839ThrThr: 2.839 ± 0.08	4.053ThrVal: 4.053 ± 0.08	0.71ThrTrp: 0.71 ± 0.028	1.077ThrTyr: 1.077 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	8.401ValAla: 8.401 ± 0.117	0.646ValCys: 0.646 ± 0.03	4.01ValAsp: 4.01 ± 0.072	3.823ValGlu: 3.823 ± 0.07	2.43ValPhe: 2.43 ± 0.054	5.411ValGly: 5.411 ± 0.1	1.494ValHis: 1.494 ± 0.05	3.405ValIle: 3.405 ± 0.06	2.186ValLys: 2.186 ± 0.06	8.212ValLeu: 8.212 ± 0.115	1.966ValMet: 1.966 ± 0.052	1.997ValAsn: 1.997 ± 0.054	4.12ValPro: 4.12 ± 0.065	3.004ValGln: 3.004 ± 0.059	4.999ValArg: 4.999 ± 0.074	4.425ValSer: 4.425 ± 0.076	3.804ValThr: 3.804 ± 0.073	5.841ValVal: 5.841 ± 0.097	0.883ValTrp: 0.883 ± 0.032	1.471ValTyr: 1.471 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.186TrpAla: 1.186 ± 0.042	0.136TrpCys: 0.136 ± 0.012	0.572TrpAsp: 0.572 ± 0.026	0.591TrpGlu: 0.591 ± 0.026	0.524TrpPhe: 0.524 ± 0.024	0.879TrpGly: 0.879 ± 0.031	0.427TrpHis: 0.427 ± 0.021	0.613TrpIle: 0.613 ± 0.029	0.488TrpLys: 0.488 ± 0.021	2.264TrpLeu: 2.264 ± 0.058	0.413TrpMet: 0.413 ± 0.022	0.408TrpAsn: 0.408 ± 0.021	0.731TrpPro: 0.731 ± 0.028	1.083TrpGln: 1.083 ± 0.031	1.178TrpArg: 1.178 ± 0.037	0.689TrpSer: 0.689 ± 0.028	0.66TrpThr: 0.66 ± 0.03	1.043TrpVal: 1.043 ± 0.035	0.26TrpTrp: 0.26 ± 0.018	0.305TrpTyr: 0.305 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.173TyrAla: 2.173 ± 0.042	0.232TyrCys: 0.232 ± 0.015	1.23TyrAsp: 1.23 ± 0.04	1.088TyrGlu: 1.088 ± 0.038	0.879TyrPhe: 0.879 ± 0.03	1.902TyrGly: 1.902 ± 0.051	0.499TyrHis: 0.499 ± 0.024	0.81TyrIle: 0.81 ± 0.031	0.547TyrLys: 0.547 ± 0.028	2.332TyrLeu: 2.332 ± 0.057	0.396TyrMet: 0.396 ± 0.024	0.644TyrAsn: 0.644 ± 0.033	1.12TyrPro: 1.12 ± 0.035	1.011TyrGln: 1.011 ± 0.034	1.922TyrArg: 1.922 ± 0.049	1.166TyrSer: 1.166 ± 0.04	1.193TyrThr: 1.193 ± 0.039	1.563TyrVal: 1.563 ± 0.044	0.392TyrTrp: 0.392 ± 0.024	0.633TyrTyr: 0.633 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2665 proteins (918189 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---