Amino acid dipepetide frequency for Capnocytophaga sp. oral taxon 338 str. F0234

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.257AlaAla: 3.257 ± 0.088	0.713AlaCys: 0.713 ± 0.038	2.9AlaAsp: 2.9 ± 0.069	3.619AlaGlu: 3.619 ± 0.081	3.291AlaPhe: 3.291 ± 0.068	3.761AlaGly: 3.761 ± 0.098	1.25AlaHis: 1.25 ± 0.042	5.104AlaIle: 5.104 ± 0.092	4.685AlaLys: 4.685 ± 0.081	6.57AlaLeu: 6.57 ± 0.114	1.479AlaMet: 1.479 ± 0.045	2.972AlaAsn: 2.972 ± 0.078	2.352AlaPro: 2.352 ± 0.065	3.232AlaGln: 3.232 ± 0.072	2.171AlaArg: 2.171 ± 0.06	3.658AlaSer: 3.658 ± 0.082	3.793AlaThr: 3.793 ± 0.1	3.401AlaVal: 3.401 ± 0.068	0.529AlaTrp: 0.529 ± 0.026	2.693AlaTyr: 2.693 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.448CysAla: 0.448 ± 0.03	0.117CysCys: 0.117 ± 0.014	0.376CysAsp: 0.376 ± 0.025	0.534CysGlu: 0.534 ± 0.026	0.489CysPhe: 0.489 ± 0.03	0.604CysGly: 0.604 ± 0.033	0.241CysHis: 0.241 ± 0.022	0.685CysIle: 0.685 ± 0.028	0.617CysLys: 0.617 ± 0.032	0.79CysLeu: 0.79 ± 0.035	0.179CysMet: 0.179 ± 0.014	0.484CysAsn: 0.484 ± 0.024	0.337CysPro: 0.337 ± 0.024	0.358CysGln: 0.358 ± 0.023	0.301CysArg: 0.301 ± 0.023	0.56CysSer: 0.56 ± 0.029	0.493CysThr: 0.493 ± 0.029	0.473CysVal: 0.473 ± 0.027	0.089CysTrp: 0.089 ± 0.01	0.454CysTyr: 0.454 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	2.889AspAla: 2.889 ± 0.073	0.406AspCys: 0.406 ± 0.024	2.268AspAsp: 2.268 ± 0.063	2.953AspGlu: 2.953 ± 0.073	3.462AspPhe: 3.462 ± 0.06	2.742AspGly: 2.742 ± 0.07	0.728AspHis: 0.728 ± 0.032	4.436AspIle: 4.436 ± 0.074	4.519AspLys: 4.519 ± 0.095	4.371AspLeu: 4.371 ± 0.084	1.09AspMet: 1.09 ± 0.037	2.801AspAsn: 2.801 ± 0.069	1.703AspPro: 1.703 ± 0.056	1.153AspGln: 1.153 ± 0.041	1.862AspArg: 1.862 ± 0.05	2.722AspSer: 2.722 ± 0.069	3.064AspThr: 3.064 ± 0.063	2.588AspVal: 2.588 ± 0.071	0.658AspTrp: 0.658 ± 0.029	2.781AspTyr: 2.781 ± 0.066	0.0AspXaa: 0.0 ± 0.0
Glu	4.557GluAla: 4.557 ± 0.098	0.441GluCys: 0.441 ± 0.026	3.287GluAsp: 3.287 ± 0.063	6.262GluGlu: 6.262 ± 0.142	2.545GluPhe: 2.545 ± 0.066	4.323GluGly: 4.323 ± 0.079	1.302GluHis: 1.302 ± 0.042	5.501GluIle: 5.501 ± 0.094	7.261GluLys: 7.261 ± 0.134	6.071GluLeu: 6.071 ± 0.092	1.536GluMet: 1.536 ± 0.046	4.302GluAsn: 4.302 ± 0.078	1.588GluPro: 1.588 ± 0.047	3.048GluGln: 3.048 ± 0.067	3.237GluArg: 3.237 ± 0.079	3.025GluSer: 3.025 ± 0.072	3.23GluThr: 3.23 ± 0.067	4.852GluVal: 4.852 ± 0.109	0.621GluTrp: 0.621 ± 0.03	3.016GluTyr: 3.016 ± 0.074	0.0GluXaa: 0.0 ± 0.0
Phe	3.057PheAla: 3.057 ± 0.074	0.552PheCys: 0.552 ± 0.028	2.748PheAsp: 2.748 ± 0.067	3.025PheGlu: 3.025 ± 0.075	3.298PhePhe: 3.298 ± 0.089	3.065PheGly: 3.065 ± 0.083	0.953PheHis: 0.953 ± 0.032	4.07PheIle: 4.07 ± 0.095	3.146PheLys: 3.146 ± 0.073	5.385PheLeu: 5.385 ± 0.097	1.062PheMet: 1.062 ± 0.036	2.356PheAsn: 2.356 ± 0.053	2.012PhePro: 2.012 ± 0.056	1.63PheGln: 1.63 ± 0.049	1.855PheArg: 1.855 ± 0.055	4.348PheSer: 4.348 ± 0.085	2.898PheThr: 2.898 ± 0.074	3.247PheVal: 3.247 ± 0.079	0.6PheTrp: 0.6 ± 0.033	2.511PheTyr: 2.511 ± 0.06	0.0PheXaa: 0.0 ± 0.0
Gly	3.958GlyAla: 3.958 ± 0.076	0.598GlyCys: 0.598 ± 0.047	3.009GlyAsp: 3.009 ± 0.076	4.111GlyGlu: 4.111 ± 0.083	3.045GlyPhe: 3.045 ± 0.071	4.346GlyGly: 4.346 ± 0.096	1.089GlyHis: 1.089 ± 0.033	5.09GlyIle: 5.09 ± 0.09	5.787GlyLys: 5.787 ± 0.088	4.879GlyLeu: 4.879 ± 0.102	1.5GlyMet: 1.5 ± 0.045	3.453GlyAsn: 3.453 ± 0.081	0.673GlyPro: 0.673 ± 0.036	1.938GlyGln: 1.938 ± 0.056	2.339GlyArg: 2.339 ± 0.059	3.17GlySer: 3.17 ± 0.078	3.717GlyThr: 3.717 ± 0.118	4.264GlyVal: 4.264 ± 0.103	0.62GlyTrp: 0.62 ± 0.029	2.916GlyTyr: 2.916 ± 0.064	0.0GlyXaa: 0.0 ± 0.0
His	0.921HisAla: 0.921 ± 0.036	0.228HisCys: 0.228 ± 0.017	0.64HisAsp: 0.64 ± 0.03	0.806HisGlu: 0.806 ± 0.033	1.365HisPhe: 1.365 ± 0.046	0.955HisGly: 0.955 ± 0.039	0.464HisHis: 0.464 ± 0.028	1.79HisIle: 1.79 ± 0.052	1.441HisLys: 1.441 ± 0.052	2.209HisLeu: 2.209 ± 0.054	0.195HisMet: 0.195 ± 0.016	0.946HisAsn: 0.946 ± 0.035	0.926HisPro: 0.926 ± 0.037	0.784HisGln: 0.784 ± 0.04	0.804HisArg: 0.804 ± 0.034	1.317HisSer: 1.317 ± 0.043	1.275HisThr: 1.275 ± 0.043	0.664HisVal: 0.664 ± 0.03	0.3HisTrp: 0.3 ± 0.021	1.093HisTyr: 1.093 ± 0.043	0.0HisXaa: 0.0 ± 0.0
Ile	5.666IleAla: 5.666 ± 0.101	0.708IleCys: 0.708 ± 0.03	4.391IleAsp: 4.391 ± 0.083	5.715IleGlu: 5.715 ± 0.1	4.09IlePhe: 4.09 ± 0.1	5.044IleGly: 5.044 ± 0.095	1.604IleHis: 1.604 ± 0.046	6.122IleIle: 6.122 ± 0.111	5.522IleLys: 5.522 ± 0.096	7.381IleLeu: 7.381 ± 0.12	1.325IleMet: 1.325 ± 0.048	3.936IleAsn: 3.936 ± 0.093	3.61IlePro: 3.61 ± 0.069	2.753IleGln: 2.753 ± 0.059	3.24IleArg: 3.24 ± 0.07	5.452IleSer: 5.452 ± 0.094	5.21IleThr: 5.21 ± 0.093	4.529IleVal: 4.529 ± 0.093	0.621IleTrp: 0.621 ± 0.031	3.153IleTyr: 3.153 ± 0.073	0.0IleXaa: 0.0 ± 0.0
Lys	5.132LysAla: 5.132 ± 0.084	0.388LysCys: 0.388 ± 0.02	4.727LysAsp: 4.727 ± 0.087	8.33LysGlu: 8.33 ± 0.121	2.467LysPhe: 2.467 ± 0.067	5.512LysGly: 5.512 ± 0.087	1.359LysHis: 1.359 ± 0.043	6.294LysIle: 6.294 ± 0.103	7.252LysLys: 7.252 ± 0.13	5.813LysLeu: 5.813 ± 0.088	2.077LysMet: 2.077 ± 0.059	5.102LysAsn: 5.102 ± 0.101	2.285LysPro: 2.285 ± 0.051	2.973LysGln: 2.973 ± 0.073	3.421LysArg: 3.421 ± 0.079	3.773LysSer: 3.773 ± 0.083	4.15LysThr: 4.15 ± 0.07	4.973LysVal: 4.973 ± 0.098	0.806LysTrp: 0.806 ± 0.034	3.621LysTyr: 3.621 ± 0.071	0.0LysXaa: 0.0 ± 0.0
Leu	5.825LeuAla: 5.825 ± 0.097	0.902LeuCys: 0.902 ± 0.038	4.222LeuAsp: 4.222 ± 0.078	5.854LeuGlu: 5.854 ± 0.098	5.298LeuPhe: 5.298 ± 0.103	5.378LeuGly: 5.378 ± 0.107	1.872LeuHis: 1.872 ± 0.054	6.762LeuIle: 6.762 ± 0.126	7.311LeuLys: 7.311 ± 0.105	10.133LeuLeu: 10.133 ± 0.161	1.959LeuMet: 1.959 ± 0.054	4.364LeuAsn: 4.364 ± 0.083	4.03LeuPro: 4.03 ± 0.072	4.007LeuGln: 4.007 ± 0.069	3.876LeuArg: 3.876 ± 0.075	7.918LeuSer: 7.918 ± 0.125	5.592LeuThr: 5.592 ± 0.094	4.901LeuVal: 4.901 ± 0.088	1.05LeuTrp: 1.05 ± 0.035	4.128LeuTyr: 4.128 ± 0.096	0.0LeuXaa: 0.0 ± 0.0
Met	1.433MetAla: 1.433 ± 0.054	0.139MetCys: 0.139 ± 0.014	1.118MetAsp: 1.118 ± 0.038	1.473MetGlu: 1.473 ± 0.043	0.765MetPhe: 0.765 ± 0.032	1.473MetGly: 1.473 ± 0.042	0.364MetHis: 0.364 ± 0.022	1.619MetIle: 1.619 ± 0.049	2.189MetLys: 2.189 ± 0.049	2.027MetLeu: 2.027 ± 0.048	0.528MetMet: 0.528 ± 0.029	1.381MetAsn: 1.381 ± 0.043	0.816MetPro: 0.816 ± 0.033	0.886MetGln: 0.886 ± 0.04	0.99MetArg: 0.99 ± 0.034	1.193MetSer: 1.193 ± 0.043	1.019MetThr: 1.019 ± 0.041	1.261MetVal: 1.261 ± 0.045	0.147MetTrp: 0.147 ± 0.014	0.713MetTyr: 0.713 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	3.285AsnAla: 3.285 ± 0.084	0.458AsnCys: 0.458 ± 0.026	2.479AsnAsp: 2.479 ± 0.063	3.245AsnGlu: 3.245 ± 0.07	2.627AsnPhe: 2.627 ± 0.078	3.098AsnGly: 3.098 ± 0.063	1.049AsnHis: 1.049 ± 0.038	4.723AsnIle: 4.723 ± 0.093	4.13AsnLys: 4.13 ± 0.085	4.693AsnLeu: 4.693 ± 0.096	1.117AsnMet: 1.117 ± 0.042	3.133AsnAsn: 3.133 ± 0.086	2.588AsnPro: 2.588 ± 0.059	1.872AsnGln: 1.872 ± 0.049	2.169AsnArg: 2.169 ± 0.058	2.893AsnSer: 2.893 ± 0.06	3.399AsnThr: 3.399 ± 0.079	2.758AsnVal: 2.758 ± 0.072	0.576AsnTrp: 0.576 ± 0.027	2.608AsnTyr: 2.608 ± 0.058	0.0AsnXaa: 0.0 ± 0.0
Pro	1.967ProAla: 1.967 ± 0.063	0.31ProCys: 0.31 ± 0.023	1.734ProAsp: 1.734 ± 0.054	2.825ProGlu: 2.825 ± 0.058	2.113ProPhe: 2.113 ± 0.051	1.214ProGly: 1.214 ± 0.059	0.75ProHis: 0.75 ± 0.031	3.181ProIle: 3.181 ± 0.071	2.906ProLys: 2.906 ± 0.069	3.582ProLeu: 3.582 ± 0.076	0.873ProMet: 0.873 ± 0.036	2.147ProAsn: 2.147 ± 0.057	0.99ProPro: 0.99 ± 0.045	1.626ProGln: 1.626 ± 0.054	0.959ProArg: 0.959 ± 0.041	2.384ProSer: 2.384 ± 0.068	2.46ProThr: 2.46 ± 0.068	2.032ProVal: 2.032 ± 0.058	0.313ProTrp: 0.313 ± 0.022	1.854ProTyr: 1.854 ± 0.054	0.0ProXaa: 0.0 ± 0.0
Gln	2.595GlnAla: 2.595 ± 0.073	0.265GlnCys: 0.265 ± 0.02	1.528GlnAsp: 1.528 ± 0.048	3.214GlnGlu: 3.214 ± 0.07	1.536GlnPhe: 1.536 ± 0.047	2.539GlnGly: 2.539 ± 0.062	0.693GlnHis: 0.693 ± 0.029	2.882GlnIle: 2.882 ± 0.072	3.675GlnLys: 3.675 ± 0.079	3.655GlnLeu: 3.655 ± 0.088	1.05GlnMet: 1.05 ± 0.04	1.864GlnAsn: 1.864 ± 0.058	1.209GlnPro: 1.209 ± 0.042	1.916GlnGln: 1.916 ± 0.064	1.739GlnArg: 1.739 ± 0.055	1.982GlnSer: 1.982 ± 0.055	2.161GlnThr: 2.161 ± 0.06	2.52GlnVal: 2.52 ± 0.062	0.638GlnTrp: 0.638 ± 0.033	1.807GlnTyr: 1.807 ± 0.057	0.0GlnXaa: 0.0 ± 0.0
Arg	2.324ArgAla: 2.324 ± 0.065	0.256ArgCys: 0.256 ± 0.018	1.834ArgAsp: 1.834 ± 0.062	3.001ArgGlu: 3.001 ± 0.072	1.96ArgPhe: 1.96 ± 0.052	2.076ArgGly: 2.076 ± 0.055	0.674ArgHis: 0.674 ± 0.028	3.569ArgIle: 3.569 ± 0.073	3.361ArgLys: 3.361 ± 0.078	3.675ArgLeu: 3.675 ± 0.083	1.03ArgMet: 1.03 ± 0.04	2.203ArgAsn: 2.203 ± 0.059	1.273ArgPro: 1.273 ± 0.041	1.358ArgGln: 1.358 ± 0.039	1.622ArgArg: 1.622 ± 0.051	1.97ArgSer: 1.97 ± 0.054	2.341ArgThr: 2.341 ± 0.063	2.251ArgVal: 2.251 ± 0.062	0.426ArgTrp: 0.426 ± 0.024	2.018ArgTyr: 2.018 ± 0.058	0.0ArgXaa: 0.0 ± 0.0
Ser	3.415SerAla: 3.415 ± 0.078	0.613SerCys: 0.613 ± 0.029	3.062SerAsp: 3.062 ± 0.066	3.637SerGlu: 3.637 ± 0.088	3.93SerPhe: 3.93 ± 0.082	3.661SerGly: 3.661 ± 0.081	1.143SerHis: 1.143 ± 0.041	4.653SerIle: 4.653 ± 0.084	4.255SerLys: 4.255 ± 0.083	6.712SerLeu: 6.712 ± 0.111	1.149SerMet: 1.149 ± 0.037	2.765SerAsn: 2.765 ± 0.076	2.375SerPro: 2.375 ± 0.052	2.701SerGln: 2.701 ± 0.06	2.065SerArg: 2.065 ± 0.06	3.851SerSer: 3.851 ± 0.092	3.04SerThr: 3.04 ± 0.073	3.718SerVal: 3.718 ± 0.083	0.748SerTrp: 0.748 ± 0.032	3.056SerTyr: 3.056 ± 0.064	0.0SerXaa: 0.0 ± 0.0
Thr	3.514ThrAla: 3.514 ± 0.108	0.422ThrCys: 0.422 ± 0.027	3.109ThrAsp: 3.109 ± 0.073	3.839ThrGlu: 3.839 ± 0.071	3.282ThrPhe: 3.282 ± 0.067	3.655ThrGly: 3.655 ± 0.105	1.338ThrHis: 1.338 ± 0.037	4.684ThrIle: 4.684 ± 0.115	3.583ThrLys: 3.583 ± 0.08	6.286ThrLeu: 6.286 ± 0.094	0.939ThrMet: 0.939 ± 0.037	2.693ThrAsn: 2.693 ± 0.074	3.241ThrPro: 3.241 ± 0.097	2.561ThrGln: 2.561 ± 0.056	1.68ThrArg: 1.68 ± 0.049	3.425ThrSer: 3.425 ± 0.083	3.573ThrThr: 3.573 ± 0.096	3.017ThrVal: 3.017 ± 0.105	0.446ThrTrp: 0.446 ± 0.023	2.937ThrTyr: 2.937 ± 0.083	0.0ThrXaa: 0.0 ± 0.0
Val	4.019ValAla: 4.019 ± 0.085	0.606ValCys: 0.606 ± 0.026	2.705ValAsp: 2.705 ± 0.06	3.894ValGlu: 3.894 ± 0.074	3.04ValPhe: 3.04 ± 0.066	3.725ValGly: 3.725 ± 0.086	0.959ValHis: 0.959 ± 0.042	4.548ValIle: 4.548 ± 0.082	4.3ValLys: 4.3 ± 0.081	5.548ValLeu: 5.548 ± 0.106	1.27ValMet: 1.27 ± 0.042	2.782ValAsn: 2.782 ± 0.07	2.272ValPro: 2.272 ± 0.07	2.032ValGln: 2.032 ± 0.06	2.44ValArg: 2.44 ± 0.063	3.827ValSer: 3.827 ± 0.084	3.427ValThr: 3.427 ± 0.137	3.681ValVal: 3.681 ± 0.096	0.561ValTrp: 0.561 ± 0.028	2.444ValTyr: 2.444 ± 0.059	0.0ValXaa: 0.0 ± 0.0
Trp	0.618TrpAla: 0.618 ± 0.029	0.087TrpCys: 0.087 ± 0.011	0.573TrpAsp: 0.573 ± 0.027	0.794TrpGlu: 0.794 ± 0.033	0.488TrpPhe: 0.488 ± 0.029	0.729TrpGly: 0.729 ± 0.034	0.228TrpHis: 0.228 ± 0.017	0.84TrpIle: 0.84 ± 0.035	0.83TrpLys: 0.83 ± 0.037	1.077TrpLeu: 1.077 ± 0.04	0.265TrpMet: 0.265 ± 0.019	0.546TrpAsn: 0.546 ± 0.031	0.097TrpPro: 0.097 ± 0.013	0.534TrpGln: 0.534 ± 0.028	0.468TrpArg: 0.468 ± 0.026	0.496TrpSer: 0.496 ± 0.026	0.438TrpThr: 0.438 ± 0.022	0.722TrpVal: 0.722 ± 0.035	0.145TrpTrp: 0.145 ± 0.015	0.501TrpTyr: 0.501 ± 0.027	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.549TyrAla: 2.549 ± 0.061	0.42TyrCys: 0.42 ± 0.022	2.488TyrAsp: 2.488 ± 0.076	2.874TyrGlu: 2.874 ± 0.072	2.726TyrPhe: 2.726 ± 0.075	2.603TyrGly: 2.603 ± 0.077	1.059TyrHis: 1.059 ± 0.037	3.521TyrIle: 3.521 ± 0.07	3.683TyrLys: 3.683 ± 0.07	4.525TyrLeu: 4.525 ± 0.082	0.906TyrMet: 0.906 ± 0.032	2.669TyrAsn: 2.669 ± 0.066	1.844TyrPro: 1.844 ± 0.047	2.108TyrGln: 2.108 ± 0.06	1.983TyrArg: 1.983 ± 0.056	2.587TyrSer: 2.587 ± 0.057	2.945TyrThr: 2.945 ± 0.082	2.228TyrVal: 2.228 ± 0.054	0.582TyrTrp: 0.582 ± 0.025	2.421TyrTyr: 2.421 ± 0.072	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2444 proteins (750425 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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