Amino acid dipepetide frequency for Gordonia amarae NBRC 15530

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.96AlaAla: 18.96 ± 0.17
0.932AlaCys: 0.932 ± 0.026
9.301AlaAsp: 9.301 ± 0.098
7.337AlaGlu: 7.337 ± 0.077
3.37AlaPhe: 3.37 ± 0.045
12.412AlaGly: 12.412 ± 0.093
2.526AlaHis: 2.526 ± 0.046
5.545AlaIle: 5.545 ± 0.067
3.084AlaLys: 3.084 ± 0.058
11.974AlaLeu: 11.974 ± 0.096
2.618AlaMet: 2.618 ± 0.049
2.239AlaAsn: 2.239 ± 0.04
6.378AlaPro: 6.378 ± 0.087
3.89AlaGln: 3.89 ± 0.052
8.334AlaArg: 8.334 ± 0.087
5.859AlaSer: 5.859 ± 0.063
7.663AlaThr: 7.663 ± 0.07
11.253AlaVal: 11.253 ± 0.095
1.467AlaTrp: 1.467 ± 0.032
2.333AlaTyr: 2.333 ± 0.039
0.0AlaXaa: 0.0 ± 0.0
Cys
1.009CysAla: 1.009 ± 0.032
0.082CysCys: 0.082 ± 0.009
0.495CysAsp: 0.495 ± 0.019
0.381CysGlu: 0.381 ± 0.018
0.209CysPhe: 0.209 ± 0.011
0.912CysGly: 0.912 ± 0.025
0.17CysHis: 0.17 ± 0.01
0.235CysIle: 0.235 ± 0.012
0.14CysLys: 0.14 ± 0.009
0.607CysLeu: 0.607 ± 0.021
0.133CysMet: 0.133 ± 0.008
0.145CysAsn: 0.145 ± 0.01
0.43CysPro: 0.43 ± 0.017
0.169CysGln: 0.169 ± 0.01
0.512CysArg: 0.512 ± 0.02
0.455CysSer: 0.455 ± 0.017
0.478CysThr: 0.478 ± 0.018
0.645CysVal: 0.645 ± 0.023
0.125CysTrp: 0.125 ± 0.011
0.173CysTyr: 0.173 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
8.188AspAla: 8.188 ± 0.081
0.426AspCys: 0.426 ± 0.018
5.218AspAsp: 5.218 ± 0.07
4.314AspGlu: 4.314 ± 0.067
1.808AspPhe: 1.808 ± 0.035
6.338AspGly: 6.338 ± 0.073
1.473AspHis: 1.473 ± 0.033
2.897AspIle: 2.897 ± 0.042
1.616AspLys: 1.616 ± 0.035
6.558AspLeu: 6.558 ± 0.073
1.036AspMet: 1.036 ± 0.027
1.361AspAsn: 1.361 ± 0.036
4.553AspPro: 4.553 ± 0.06
1.711AspGln: 1.711 ± 0.038
4.749AspArg: 4.749 ± 0.062
3.28AspSer: 3.28 ± 0.053
3.735AspThr: 3.735 ± 0.044
5.351AspVal: 5.351 ± 0.062
0.973AspTrp: 0.973 ± 0.027
1.416AspTyr: 1.416 ± 0.036
0.0AspXaa: 0.0 ± 0.0
Glu
5.883GluAla: 5.883 ± 0.071
0.331GluCys: 0.331 ± 0.015
2.366GluAsp: 2.366 ± 0.044
2.34GluGlu: 2.34 ± 0.041
1.851GluPhe: 1.851 ± 0.032
3.315GluGly: 3.315 ± 0.055
1.408GluHis: 1.408 ± 0.032
2.832GluIle: 2.832 ± 0.049
1.43GluLys: 1.43 ± 0.034
6.392GluLeu: 6.392 ± 0.066
1.023GluMet: 1.023 ± 0.028
1.227GluAsn: 1.227 ± 0.026
2.932GluPro: 2.932 ± 0.054
2.12GluGln: 2.12 ± 0.038
4.238GluArg: 4.238 ± 0.057
3.081GluSer: 3.081 ± 0.046
2.725GluThr: 2.725 ± 0.045
4.543GluVal: 4.543 ± 0.053
0.805GluTrp: 0.805 ± 0.025
1.2GluTyr: 1.2 ± 0.031
0.0GluXaa: 0.0 ± 0.0
Phe
3.993PheAla: 3.993 ± 0.055
0.282PheCys: 0.282 ± 0.012
2.403PheAsp: 2.403 ± 0.051
1.415PheGlu: 1.415 ± 0.03
0.922PhePhe: 0.922 ± 0.027
3.523PheGly: 3.523 ± 0.05
0.6PheHis: 0.6 ± 0.019
1.171PheIle: 1.171 ± 0.029
0.523PheLys: 0.523 ± 0.02
2.387PheLeu: 2.387 ± 0.046
0.475PheMet: 0.475 ± 0.019
0.713PheAsn: 0.713 ± 0.022
1.377PhePro: 1.377 ± 0.032
0.623PheGln: 0.623 ± 0.016
1.688PheArg: 1.688 ± 0.033
1.727PheSer: 1.727 ± 0.036
2.216PheThr: 2.216 ± 0.035
2.584PheVal: 2.584 ± 0.042
0.396PheTrp: 0.396 ± 0.017
0.661PheTyr: 0.661 ± 0.02
0.0PheXaa: 0.0 ± 0.0
Gly
10.265GlyAla: 10.265 ± 0.091
0.741GlyCys: 0.741 ± 0.022
5.692GlyAsp: 5.692 ± 0.064
4.671GlyGlu: 4.671 ± 0.056
3.085GlyPhe: 3.085 ± 0.047
7.941GlyGly: 7.941 ± 0.091
1.959GlyHis: 1.959 ± 0.033
4.522GlyIle: 4.522 ± 0.065
2.862GlyLys: 2.862 ± 0.046
8.449GlyLeu: 8.449 ± 0.081
2.067GlyMet: 2.067 ± 0.04
1.994GlyAsn: 1.994 ± 0.044
4.557GlyPro: 4.557 ± 0.068
2.804GlyGln: 2.804 ± 0.052
6.328GlyArg: 6.328 ± 0.071
5.494GlySer: 5.494 ± 0.058
5.956GlyThr: 5.956 ± 0.069
7.786GlyVal: 7.786 ± 0.076
1.444GlyTrp: 1.444 ± 0.031
2.371GlyTyr: 2.371 ± 0.037
0.0GlyXaa: 0.0 ± 0.0
His
2.302HisAla: 2.302 ± 0.039
0.199HisCys: 0.199 ± 0.011
1.372HisAsp: 1.372 ± 0.031
1.07HisGlu: 1.07 ± 0.027
0.591HisPhe: 0.591 ± 0.018
1.972HisGly: 1.972 ± 0.038
0.646HisHis: 0.646 ± 0.02
0.902HisIle: 0.902 ± 0.024
0.429HisLys: 0.429 ± 0.016
2.022HisLeu: 2.022 ± 0.039
0.338HisMet: 0.338 ± 0.016
0.49HisAsn: 0.49 ± 0.019
1.568HisPro: 1.568 ± 0.033
0.583HisGln: 0.583 ± 0.017
1.77HisArg: 1.77 ± 0.036
1.116HisSer: 1.116 ± 0.026
1.251HisThr: 1.251 ± 0.033
1.531HisVal: 1.531 ± 0.035
0.328HisTrp: 0.328 ± 0.013
0.488HisTyr: 0.488 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
6.753IleAla: 6.753 ± 0.074
0.404IleCys: 0.404 ± 0.016
3.842IleAsp: 3.842 ± 0.049
2.764IleGlu: 2.764 ± 0.044
1.065IlePhe: 1.065 ± 0.025
4.796IleGly: 4.796 ± 0.059
0.818IleHis: 0.818 ± 0.024
1.843IleIle: 1.843 ± 0.044
1.005IleLys: 1.005 ± 0.027
3.468IleLeu: 3.468 ± 0.05
0.647IleMet: 0.647 ± 0.024
1.133IleAsn: 1.133 ± 0.027
2.529IlePro: 2.529 ± 0.038
0.82IleGln: 0.82 ± 0.026
2.807IleArg: 2.807 ± 0.043
2.48IleSer: 2.48 ± 0.043
3.196IleThr: 3.196 ± 0.049
4.25IleVal: 4.25 ± 0.056
0.478IleTrp: 0.478 ± 0.018
0.787IleTyr: 0.787 ± 0.024
0.0IleXaa: 0.0 ± 0.0
Lys
3.004LysAla: 3.004 ± 0.051
0.126LysCys: 0.126 ± 0.01
1.276LysAsp: 1.276 ± 0.032
1.045LysGlu: 1.045 ± 0.026
0.629LysPhe: 0.629 ± 0.02
1.841LysGly: 1.841 ± 0.041
0.516LysHis: 0.516 ± 0.018
1.202LysIle: 1.202 ± 0.031
0.917LysLys: 0.917 ± 0.031
2.26LysLeu: 2.26 ± 0.037
0.521LysMet: 0.521 ± 0.019
0.643LysAsn: 0.643 ± 0.023
1.489LysPro: 1.489 ± 0.034
0.817LysGln: 0.817 ± 0.024
1.672LysArg: 1.672 ± 0.035
1.437LysSer: 1.437 ± 0.033
1.539LysThr: 1.539 ± 0.035
2.328LysVal: 2.328 ± 0.046
0.33LysTrp: 0.33 ± 0.015
0.577LysTyr: 0.577 ± 0.021
0.0LysXaa: 0.0 ± 0.0
Leu
13.065LeuAla: 13.065 ± 0.1
0.78LeuCys: 0.78 ± 0.026
6.762LeuAsp: 6.762 ± 0.064
4.0LeuGlu: 4.0 ± 0.059
2.567LeuPhe: 2.567 ± 0.046
8.552LeuGly: 8.552 ± 0.081
1.868LeuHis: 1.868 ± 0.038
4.447LeuIle: 4.447 ± 0.066
1.935LeuLys: 1.935 ± 0.041
8.869LeuLeu: 8.869 ± 0.107
1.651LeuMet: 1.651 ± 0.031
2.003LeuAsn: 2.003 ± 0.034
5.446LeuPro: 5.446 ± 0.07
1.99LeuGln: 1.99 ± 0.039
7.339LeuArg: 7.339 ± 0.075
5.765LeuSer: 5.765 ± 0.059
6.742LeuThr: 6.742 ± 0.07
8.061LeuVal: 8.061 ± 0.085
1.213LeuTrp: 1.213 ± 0.028
1.641LeuTyr: 1.641 ± 0.033
0.0LeuXaa: 0.0 ± 0.0
Met
2.373MetAla: 2.373 ± 0.039
0.181MetCys: 0.181 ± 0.012
0.859MetAsp: 0.859 ± 0.023
0.698MetGlu: 0.698 ± 0.025
0.636MetPhe: 0.636 ± 0.024
1.383MetGly: 1.383 ± 0.036
0.369MetHis: 0.369 ± 0.016
0.967MetIle: 0.967 ± 0.022
0.485MetLys: 0.485 ± 0.017
1.936MetLeu: 1.936 ± 0.034
0.42MetMet: 0.42 ± 0.019
0.483MetAsn: 0.483 ± 0.019
1.149MetPro: 1.149 ± 0.026
0.458MetGln: 0.458 ± 0.02
1.468MetArg: 1.468 ± 0.031
1.694MetSer: 1.694 ± 0.031
1.81MetThr: 1.81 ± 0.033
1.624MetVal: 1.624 ± 0.032
0.236MetTrp: 0.236 ± 0.013
0.347MetTyr: 0.347 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
2.463AsnAla: 2.463 ± 0.038
0.168AsnCys: 0.168 ± 0.01
1.175AsnAsp: 1.175 ± 0.027
0.956AsnGlu: 0.956 ± 0.025
0.629AsnPhe: 0.629 ± 0.021
2.018AsnGly: 2.018 ± 0.035
0.44AsnHis: 0.44 ± 0.017
0.934AsnIle: 0.934 ± 0.023
0.611AsnLys: 0.611 ± 0.023
2.065AsnLeu: 2.065 ± 0.035
0.387AsnMet: 0.387 ± 0.015
0.553AsnAsn: 0.553 ± 0.022
1.815AsnPro: 1.815 ± 0.038
0.632AsnGln: 0.632 ± 0.021
1.511AsnArg: 1.511 ± 0.029
1.252AsnSer: 1.252 ± 0.029
1.392AsnThr: 1.392 ± 0.032
1.676AsnVal: 1.676 ± 0.036
0.356AsnTrp: 0.356 ± 0.014
0.495AsnTyr: 0.495 ± 0.018
0.0AsnXaa: 0.0 ± 0.0
Pro
7.443ProAla: 7.443 ± 0.091
0.264ProCys: 0.264 ± 0.013
4.774ProAsp: 4.774 ± 0.056
3.855ProGlu: 3.855 ± 0.056
1.614ProPhe: 1.614 ± 0.033
5.862ProGly: 5.862 ± 0.074
1.178ProHis: 1.178 ± 0.03
2.186ProIle: 2.186 ± 0.038
1.368ProLys: 1.368 ± 0.033
4.551ProLeu: 4.551 ± 0.066
1.083ProMet: 1.083 ± 0.025
1.132ProAsn: 1.132 ± 0.03
2.799ProPro: 2.799 ± 0.06
1.604ProGln: 1.604 ± 0.034
3.424ProArg: 3.424 ± 0.052
2.997ProSer: 2.997 ± 0.05
3.445ProThr: 3.445 ± 0.048
5.086ProVal: 5.086 ± 0.07
0.758ProTrp: 0.758 ± 0.025
1.17ProTyr: 1.17 ± 0.032
0.0ProXaa: 0.0 ± 0.0
Gln
3.25GlnAla: 3.25 ± 0.047
0.196GlnCys: 0.196 ± 0.011
1.117GlnAsp: 1.117 ± 0.03
1.095GlnGlu: 1.095 ± 0.03
0.874GlnPhe: 0.874 ± 0.022
1.905GlnGly: 1.905 ± 0.036
0.613GlnHis: 0.613 ± 0.019
1.507GlnIle: 1.507 ± 0.033
0.717GlnLys: 0.717 ± 0.023
3.003GlnLeu: 3.003 ± 0.048
0.652GlnMet: 0.652 ± 0.018
0.649GlnAsn: 0.649 ± 0.023
1.53GlnPro: 1.53 ± 0.042
1.127GlnGln: 1.127 ± 0.031
2.358GlnArg: 2.358 ± 0.042
1.51GlnSer: 1.51 ± 0.031
1.499GlnThr: 1.499 ± 0.031
2.662GlnVal: 2.662 ± 0.041
0.503GlnTrp: 0.503 ± 0.018
0.62GlnTyr: 0.62 ± 0.022
0.0GlnXaa: 0.0 ± 0.0
Arg
7.818ArgAla: 7.818 ± 0.072
0.525ArgCys: 0.525 ± 0.019
4.301ArgAsp: 4.301 ± 0.06
3.984ArgGlu: 3.984 ± 0.064
2.35ArgPhe: 2.35 ± 0.038
5.145ArgGly: 5.145 ± 0.069
1.643ArgHis: 1.643 ± 0.035
3.693ArgIle: 3.693 ± 0.049
1.826ArgLys: 1.826 ± 0.037
6.944ArgLeu: 6.944 ± 0.081
1.715ArgMet: 1.715 ± 0.033
1.659ArgAsn: 1.659 ± 0.034
3.959ArgPro: 3.959 ± 0.062
2.097ArgGln: 2.097 ± 0.033
6.213ArgArg: 6.213 ± 0.086
4.195ArgSer: 4.195 ± 0.054
4.636ArgThr: 4.636 ± 0.066
5.373ArgVal: 5.373 ± 0.058
1.226ArgTrp: 1.226 ± 0.031
1.806ArgTyr: 1.806 ± 0.036
0.0ArgXaa: 0.0 ± 0.0
Ser
7.186SerAla: 7.186 ± 0.071
0.398SerCys: 0.398 ± 0.018
3.436SerAsp: 3.436 ± 0.051
2.704SerGlu: 2.704 ± 0.049
1.707SerPhe: 1.707 ± 0.038
6.39SerGly: 6.39 ± 0.077
1.077SerHis: 1.077 ± 0.028
2.378SerIle: 2.378 ± 0.04
1.273SerLys: 1.273 ± 0.034
4.893SerLeu: 4.893 ± 0.06
1.364SerMet: 1.364 ± 0.028
1.074SerAsn: 1.074 ± 0.029
3.165SerPro: 3.165 ± 0.046
1.405SerGln: 1.405 ± 0.032
3.746SerArg: 3.746 ± 0.054
3.366SerSer: 3.366 ± 0.056
3.73SerThr: 3.73 ± 0.046
4.993SerVal: 4.993 ± 0.06
0.924SerTrp: 0.924 ± 0.025
1.234SerTyr: 1.234 ± 0.029
0.0SerXaa: 0.0 ± 0.0
Thr
8.107ThrAla: 8.107 ± 0.085
0.427ThrCys: 0.427 ± 0.017
4.457ThrAsp: 4.457 ± 0.061
3.442ThrGlu: 3.442 ± 0.054
1.881ThrPhe: 1.881 ± 0.036
6.638ThrGly: 6.638 ± 0.074
1.241ThrHis: 1.241 ± 0.03
2.947ThrIle: 2.947 ± 0.043
1.374ThrLys: 1.374 ± 0.034
5.771ThrLeu: 5.771 ± 0.062
1.26ThrMet: 1.26 ± 0.024
1.219ThrAsn: 1.219 ± 0.025
4.099ThrPro: 4.099 ± 0.054
1.495ThrGln: 1.495 ± 0.037
3.945ThrArg: 3.945 ± 0.052
3.555ThrSer: 3.555 ± 0.048
4.469ThrThr: 4.469 ± 0.07
6.163ThrVal: 6.163 ± 0.072
0.823ThrTrp: 0.823 ± 0.021
1.342ThrTyr: 1.342 ± 0.029
0.0ThrXaa: 0.0 ± 0.0
Val
11.607ValAla: 11.607 ± 0.108
0.702ValCys: 0.702 ± 0.023
6.006ValAsp: 6.006 ± 0.07
4.256ValGlu: 4.256 ± 0.051
2.619ValPhe: 2.619 ± 0.045
7.078ValGly: 7.078 ± 0.077
1.693ValHis: 1.693 ± 0.033
4.298ValIle: 4.298 ± 0.057
1.766ValLys: 1.766 ± 0.031
8.649ValLeu: 8.649 ± 0.088
1.52ValMet: 1.52 ± 0.028
1.923ValAsn: 1.923 ± 0.035
4.928ValPro: 4.928 ± 0.067
1.806ValGln: 1.806 ± 0.034
6.058ValArg: 6.058 ± 0.075
5.073ValSer: 5.073 ± 0.055
6.057ValThr: 6.057 ± 0.076
8.634ValVal: 8.634 ± 0.088
0.994ValTrp: 0.994 ± 0.026
1.548ValTyr: 1.548 ± 0.039
0.0ValXaa: 0.0 ± 0.0
Trp
1.463TrpAla: 1.463 ± 0.031
0.139TrpCys: 0.139 ± 0.009
0.778TrpAsp: 0.778 ± 0.022
0.636TrpGlu: 0.636 ± 0.024
0.537TrpPhe: 0.537 ± 0.02
0.996TrpGly: 0.996 ± 0.029
0.326TrpHis: 0.326 ± 0.013
0.652TrpIle: 0.652 ± 0.024
0.353TrpLys: 0.353 ± 0.017
1.559TrpLeu: 1.559 ± 0.033
0.344TrpMet: 0.344 ± 0.014
0.395TrpAsn: 0.395 ± 0.015
0.708TrpPro: 0.708 ± 0.021
0.587TrpGln: 0.587 ± 0.02
1.125TrpArg: 1.125 ± 0.025
0.907TrpSer: 0.907 ± 0.023
0.875TrpThr: 0.875 ± 0.026
1.043TrpVal: 1.043 ± 0.026
0.334TrpTrp: 0.334 ± 0.016
0.325TrpTyr: 0.325 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.345TyrAla: 2.345 ± 0.038
0.202TyrCys: 0.202 ± 0.011
1.369TyrAsp: 1.369 ± 0.033
1.08TyrGlu: 1.08 ± 0.027
0.734TyrPhe: 0.734 ± 0.021
1.97TyrGly: 1.97 ± 0.035
0.401TyrHis: 0.401 ± 0.018
0.728TyrIle: 0.728 ± 0.024
0.455TyrLys: 0.455 ± 0.017
2.335TyrLeu: 2.335 ± 0.039
0.321TyrMet: 0.321 ± 0.015
0.493TyrAsn: 0.493 ± 0.018
1.184TyrPro: 1.184 ± 0.032
0.65TyrGln: 0.65 ± 0.019
1.825TyrArg: 1.825 ± 0.031
1.199TyrSer: 1.199 ± 0.025
1.243TyrThr: 1.243 ± 0.031
1.63TyrVal: 1.63 ± 0.033
0.371TyrTrp: 0.371 ± 0.015
0.47TyrTyr: 0.47 ± 0.018
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4691 proteins (1599335 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski