Amino acid dipepetide frequency for Porcine circovirus 1 (PCV1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.043AlaAla: 3.043 ± 2.421
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
3.043AlaGlu: 3.043 ± 2.149
1.014AlaPhe: 1.014 ± 0.781
4.057AlaGly: 4.057 ± 1.986
1.014AlaHis: 1.014 ± 0.781
1.014AlaIle: 1.014 ± 1.015
5.071AlaLys: 5.071 ± 1.828
9.128AlaLeu: 9.128 ± 3.653
0.0AlaMet: 0.0 ± 0.0
3.043AlaAsn: 3.043 ± 0.965
6.085AlaPro: 6.085 ± 1.713
1.014AlaGln: 1.014 ± 0.781
4.057AlaArg: 4.057 ± 2.037
0.0AlaSer: 0.0 ± 0.0
4.057AlaThr: 4.057 ± 3.608
15.213AlaVal: 15.213 ± 6.503
0.0AlaTrp: 0.0 ± 0.0
2.028AlaTyr: 2.028 ± 1.123
0.0AlaXaa: 0.0 ± 0.0
Cys
4.057CysAla: 4.057 ± 1.986
1.014CysCys: 1.014 ± 1.015
1.014CysAsp: 1.014 ± 0.716
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
5.071CysGly: 5.071 ± 2.397
2.028CysHis: 2.028 ± 1.022
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.014CysLeu: 1.014 ± 1.229
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.014CysPro: 1.014 ± 1.015
0.0CysGln: 0.0 ± 0.0
1.014CysArg: 1.014 ± 1.015
2.028CysSer: 2.028 ± 1.022
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.014CysTrp: 1.014 ± 1.015
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.014AspAla: 1.014 ± 0.781
1.014AspCys: 1.014 ± 1.015
2.028AspAsp: 2.028 ± 1.433
0.0AspGlu: 0.0 ± 0.0
1.014AspPhe: 1.014 ± 0.716
1.014AspGly: 1.014 ± 0.716
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
0.0AspLys: 0.0 ± 0.0
3.043AspLeu: 3.043 ± 1.444
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
7.099AspPro: 7.099 ± 2.209
3.043AspGln: 3.043 ± 0.965
1.014AspArg: 1.014 ± 0.716
0.0AspSer: 0.0 ± 0.0
1.014AspThr: 1.014 ± 0.716
0.0AspVal: 0.0 ± 0.0
2.028AspTrp: 2.028 ± 0.884
4.057AspTyr: 4.057 ± 2.88
0.0AspXaa: 0.0 ± 0.0
Glu
8.114GluAla: 8.114 ± 3.972
2.028GluCys: 2.028 ± 1.022
2.028GluAsp: 2.028 ± 2.031
9.128GluGlu: 9.128 ± 4.397
2.028GluPhe: 2.028 ± 1.563
10.142GluGly: 10.142 ± 2.681
1.014GluHis: 1.014 ± 0.781
0.0GluIle: 0.0 ± 0.0
4.057GluLys: 4.057 ± 2.044
6.085GluLeu: 6.085 ± 1.05
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
2.028GluPro: 2.028 ± 1.15
5.071GluGln: 5.071 ± 1.964
1.014GluArg: 1.014 ± 0.781
0.0GluSer: 0.0 ± 0.0
2.028GluThr: 2.028 ± 1.433
5.071GluVal: 5.071 ± 1.964
4.057GluTrp: 4.057 ± 1.986
2.028GluTyr: 2.028 ± 1.022
0.0GluXaa: 0.0 ± 0.0
Phe
6.085PheAla: 6.085 ± 3.066
0.0PheCys: 0.0 ± 0.0
3.043PheAsp: 3.043 ± 1.907
4.057PheGlu: 4.057 ± 1.986
0.0PhePhe: 0.0 ± 0.0
2.028PheGly: 2.028 ± 1.022
1.014PheHis: 1.014 ± 0.781
1.014PheIle: 1.014 ± 0.781
0.0PheLys: 0.0 ± 0.0
2.028PheLeu: 2.028 ± 0.884
0.0PheMet: 0.0 ± 0.0
4.057PheAsn: 4.057 ± 1.428
5.071PhePro: 5.071 ± 1.964
1.014PheGln: 1.014 ± 0.781
3.043PheArg: 3.043 ± 1.507
0.0PheSer: 0.0 ± 0.0
4.057PheThr: 4.057 ± 1.428
3.043PheVal: 3.043 ± 0.965
4.057PheTrp: 4.057 ± 1.986
2.028PheTyr: 2.028 ± 0.884
0.0PheXaa: 0.0 ± 0.0
Gly
4.057GlyAla: 4.057 ± 2.044
1.014GlyCys: 1.014 ± 0.716
0.0GlyAsp: 0.0 ± 0.0
7.099GlyGlu: 7.099 ± 1.838
2.028GlyPhe: 2.028 ± 1.022
4.057GlyGly: 4.057 ± 1.428
2.028GlyHis: 2.028 ± 1.022
2.028GlyIle: 2.028 ± 1.314
4.057GlyLys: 4.057 ± 2.037
4.057GlyLeu: 4.057 ± 1.277
1.014GlyMet: 1.014 ± 1.015
1.014GlyAsn: 1.014 ± 0.781
7.099GlyPro: 7.099 ± 2.018
1.014GlyGln: 1.014 ± 0.781
6.085GlyArg: 6.085 ± 1.713
3.043GlySer: 3.043 ± 1.094
6.085GlyThr: 6.085 ± 1.352
1.014GlyVal: 1.014 ± 0.781
1.014GlyTrp: 1.014 ± 0.716
3.043GlyTyr: 3.043 ± 1.507
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
2.028HisGly: 2.028 ± 1.022
0.0HisHis: 0.0 ± 0.0
4.057HisIle: 4.057 ± 2.044
5.071HisLys: 5.071 ± 1.876
4.057HisLeu: 4.057 ± 1.428
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.028HisPro: 2.028 ± 1.563
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.014HisSer: 1.014 ± 0.781
3.043HisThr: 3.043 ± 2.344
1.014HisVal: 1.014 ± 0.716
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
1.014IleAsp: 1.014 ± 0.781
4.057IleGlu: 4.057 ± 2.044
1.014IlePhe: 1.014 ± 0.781
1.014IleGly: 1.014 ± 0.781
1.014IleHis: 1.014 ± 1.015
0.0IleIle: 0.0 ± 0.0
2.028IleLys: 2.028 ± 1.314
10.142IleLeu: 10.142 ± 1.678
1.014IleMet: 1.014 ± 0.917
5.071IleAsn: 5.071 ± 1.742
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
4.057IleArg: 4.057 ± 1.428
2.028IleSer: 2.028 ± 1.022
8.114IleThr: 8.114 ± 3.147
1.014IleVal: 1.014 ± 0.716
0.0IleTrp: 0.0 ± 0.0
1.014IleTyr: 1.014 ± 0.781
0.0IleXaa: 0.0 ± 0.0
Lys
4.057LysAla: 4.057 ± 0.856
0.0LysCys: 0.0 ± 0.0
1.014LysAsp: 1.014 ± 0.781
5.071LysGlu: 5.071 ± 1.748
1.014LysPhe: 1.014 ± 0.781
4.057LysGly: 4.057 ± 1.277
0.0LysHis: 0.0 ± 0.0
6.085LysIle: 6.085 ± 1.713
8.114LysLys: 8.114 ± 2.528
0.0LysLeu: 0.0 ± 0.0
1.014LysMet: 1.014 ± 0.716
3.043LysAsn: 3.043 ± 1.113
2.028LysPro: 2.028 ± 0.884
2.028LysGln: 2.028 ± 1.022
6.085LysArg: 6.085 ± 1.352
9.128LysSer: 9.128 ± 3.727
6.085LysThr: 6.085 ± 1.615
3.043LysVal: 3.043 ± 1.444
3.043LysTrp: 3.043 ± 1.444
1.014LysTyr: 1.014 ± 0.781
0.0LysXaa: 0.0 ± 0.0
Leu
4.057LeuAla: 4.057 ± 1.768
1.014LeuCys: 1.014 ± 0.716
3.043LeuAsp: 3.043 ± 1.507
4.057LeuGlu: 4.057 ± 2.044
6.085LeuPhe: 6.085 ± 1.713
2.028LeuGly: 2.028 ± 1.563
1.014LeuHis: 1.014 ± 0.781
6.085LeuIle: 6.085 ± 2.3
3.043LeuLys: 3.043 ± 1.507
6.085LeuLeu: 6.085 ± 2.18
0.0LeuMet: 0.0 ± 0.0
4.057LeuAsn: 4.057 ± 1.773
6.085LeuPro: 6.085 ± 2.094
7.099LeuGln: 7.099 ± 1.141
3.043LeuArg: 3.043 ± 1.094
5.071LeuSer: 5.071 ± 1.526
3.043LeuThr: 3.043 ± 1.507
3.043LeuVal: 3.043 ± 1.094
1.014LeuTrp: 1.014 ± 0.781
4.057LeuTyr: 4.057 ± 1.986
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
5.071MetPro: 5.071 ± 1.876
1.014MetGln: 1.014 ± 0.716
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
1.014MetThr: 1.014 ± 0.781
1.014MetVal: 1.014 ± 1.015
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.014AsnAla: 1.014 ± 0.781
1.014AsnCys: 1.014 ± 1.015
0.0AsnAsp: 0.0 ± 0.0
1.014AsnGlu: 1.014 ± 0.781
5.071AsnPhe: 5.071 ± 1.831
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
2.028AsnIle: 2.028 ± 1.563
8.114AsnLys: 8.114 ± 3.097
1.014AsnLeu: 1.014 ± 0.781
0.0AsnMet: 0.0 ± 0.0
3.043AsnAsn: 3.043 ± 0.965
3.043AsnPro: 3.043 ± 0.965
7.099AsnGln: 7.099 ± 1.141
1.014AsnArg: 1.014 ± 0.781
1.014AsnSer: 1.014 ± 0.781
2.028AsnThr: 2.028 ± 1.314
2.028AsnVal: 2.028 ± 1.563
0.0AsnTrp: 0.0 ± 0.0
7.099AsnTyr: 7.099 ± 2.209
0.0AsnXaa: 0.0 ± 0.0
Pro
6.085ProAla: 6.085 ± 2.625
4.057ProCys: 4.057 ± 1.986
0.0ProAsp: 0.0 ± 0.0
5.071ProGlu: 5.071 ± 1.742
3.043ProPhe: 3.043 ± 1.507
2.028ProGly: 2.028 ± 1.022
7.099ProHis: 7.099 ± 2.018
4.057ProIle: 4.057 ± 1.773
1.014ProLys: 1.014 ± 0.781
3.043ProLeu: 3.043 ± 1.507
1.014ProMet: 1.014 ± 0.715
1.014ProAsn: 1.014 ± 0.781
7.099ProPro: 7.099 ± 1.141
9.128ProGln: 9.128 ± 3.727
5.071ProArg: 5.071 ± 2.09
13.185ProSer: 13.185 ± 1.27
1.014ProThr: 1.014 ± 1.229
1.014ProVal: 1.014 ± 0.716
1.014ProTrp: 1.014 ± 0.716
6.085ProTyr: 6.085 ± 1.829
0.0ProXaa: 0.0 ± 0.0
Gln
4.057GlnAla: 4.057 ± 1.986
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
4.057GlnGlu: 4.057 ± 1.986
7.099GlnPhe: 7.099 ± 1.605
4.057GlnGly: 4.057 ± 2.044
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
1.014GlnLeu: 1.014 ± 0.781
0.0GlnMet: 0.0 ± 0.0
4.057GlnAsn: 4.057 ± 1.428
7.099GlnPro: 7.099 ± 1.469
4.057GlnGln: 4.057 ± 2.044
1.014GlnArg: 1.014 ± 0.716
5.071GlnSer: 5.071 ± 1.876
3.043GlnThr: 3.043 ± 0.965
0.0GlnVal: 0.0 ± 0.0
1.014GlnTrp: 1.014 ± 0.716
1.014GlnTyr: 1.014 ± 0.781
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
2.028ArgCys: 2.028 ± 1.022
2.028ArgAsp: 2.028 ± 0.884
3.043ArgGlu: 3.043 ± 0.965
4.057ArgPhe: 4.057 ± 1.986
4.057ArgGly: 4.057 ± 2.152
1.014ArgHis: 1.014 ± 0.781
6.085ArgIle: 6.085 ± 2.625
4.057ArgLys: 4.057 ± 2.629
3.043ArgLeu: 3.043 ± 1.507
0.0ArgMet: 0.0 ± 0.0
7.099ArgAsn: 7.099 ± 2.487
3.043ArgPro: 3.043 ± 1.647
1.014ArgGln: 1.014 ± 0.781
13.185ArgArg: 13.185 ± 5.233
5.071ArgSer: 5.071 ± 1.828
4.057ArgThr: 4.057 ± 1.773
0.0ArgVal: 0.0 ± 0.0
3.043ArgTrp: 3.043 ± 0.965
4.057ArgTyr: 4.057 ± 2.232
0.0ArgXaa: 0.0 ± 0.0
Ser
1.014SerAla: 1.014 ± 1.229
1.014SerCys: 1.014 ± 1.015
3.043SerAsp: 3.043 ± 1.444
3.043SerGlu: 3.043 ± 1.907
0.0SerPhe: 0.0 ± 0.0
9.128SerGly: 9.128 ± 1.996
1.014SerHis: 1.014 ± 0.781
2.028SerIle: 2.028 ± 1.303
7.099SerLys: 7.099 ± 2.018
4.057SerLeu: 4.057 ± 2.044
0.0SerMet: 0.0 ± 0.0
5.071SerAsn: 5.071 ± 1.742
0.0SerPro: 0.0 ± 0.0
2.028SerGln: 2.028 ± 0.884
6.085SerArg: 6.085 ± 2.695
7.099SerSer: 7.099 ± 2.339
14.199SerThr: 14.199 ± 2.395
1.014SerVal: 1.014 ± 1.229
1.014SerTrp: 1.014 ± 0.781
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
13.185ThrAla: 13.185 ± 3.694
1.014ThrCys: 1.014 ± 1.229
2.028ThrAsp: 2.028 ± 1.022
5.071ThrGlu: 5.071 ± 1.742
2.028ThrPhe: 2.028 ± 1.022
3.043ThrGly: 3.043 ± 1.507
1.014ThrHis: 1.014 ± 0.781
5.071ThrIle: 5.071 ± 3.046
1.014ThrLys: 1.014 ± 0.716
7.099ThrLeu: 7.099 ± 1.838
0.0ThrMet: 0.0 ± 0.0
3.043ThrAsn: 3.043 ± 2.344
4.057ThrPro: 4.057 ± 1.428
0.0ThrGln: 0.0 ± 0.0
3.043ThrArg: 3.043 ± 1.328
6.085ThrSer: 6.085 ± 3.524
4.057ThrThr: 4.057 ± 1.986
4.057ThrVal: 4.057 ± 2.05
1.014ThrTrp: 1.014 ± 0.781
4.057ThrTyr: 4.057 ± 1.301
0.0ThrXaa: 0.0 ± 0.0
Val
1.014ValAla: 1.014 ± 0.716
2.028ValCys: 2.028 ± 1.022
4.057ValAsp: 4.057 ± 1.986
7.099ValGlu: 7.099 ± 2.401
2.028ValPhe: 2.028 ± 1.022
2.028ValGly: 2.028 ± 0.884
1.014ValHis: 1.014 ± 0.716
2.028ValIle: 2.028 ± 0.884
3.043ValLys: 3.043 ± 1.113
3.043ValLeu: 3.043 ± 0.965
0.0ValMet: 0.0 ± 0.0
1.014ValAsn: 1.014 ± 0.781
10.142ValPro: 10.142 ± 4.624
1.014ValGln: 1.014 ± 0.781
2.028ValArg: 2.028 ± 0.884
2.028ValSer: 2.028 ± 1.433
3.043ValThr: 3.043 ± 1.407
4.057ValVal: 4.057 ± 1.768
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.014TrpAla: 1.014 ± 0.716
0.0TrpCys: 0.0 ± 0.0
2.028TrpAsp: 2.028 ± 1.433
0.0TrpGlu: 0.0 ± 0.0
1.014TrpPhe: 1.014 ± 0.781
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
6.085TrpLys: 6.085 ± 2.191
2.028TrpLeu: 2.028 ± 0.884
0.0TrpMet: 0.0 ± 0.0
1.014TrpAsn: 1.014 ± 0.781
1.014TrpPro: 1.014 ± 0.781
0.0TrpGln: 0.0 ± 0.0
2.028TrpArg: 2.028 ± 1.123
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
2.028TrpVal: 2.028 ± 1.022
1.014TrpTrp: 1.014 ± 0.716
6.085TrpTyr: 6.085 ± 1.713
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.014TyrAla: 1.014 ± 0.781
2.028TyrCys: 2.028 ± 1.022
1.014TyrAsp: 1.014 ± 0.781
1.014TyrGlu: 1.014 ± 0.781
7.099TyrPhe: 7.099 ± 3.599
1.014TyrGly: 1.014 ± 0.716
2.028TyrHis: 2.028 ± 0.884
1.014TyrIle: 1.014 ± 0.781
4.057TyrLys: 4.057 ± 1.986
3.043TyrLeu: 3.043 ± 1.779
3.043TyrMet: 3.043 ± 1.704
0.0TyrAsn: 0.0 ± 0.0
2.028TyrPro: 2.028 ± 0.884
1.014TyrGln: 1.014 ± 1.015
7.099TyrArg: 7.099 ± 2.209
6.085TyrSer: 6.085 ± 1.829
0.0TyrThr: 0.0 ± 0.0
3.043TyrVal: 3.043 ± 1.507
1.014TyrTrp: 1.014 ± 0.716
2.028TyrTyr: 2.028 ± 1.123
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (987 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski