Amino acid dipepetide frequency for Torque teno Tadarida brasiliensis virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.866AlaAla: 3.866 ± 5.6
1.289AlaCys: 1.289 ± 1.864
3.866AlaAsp: 3.866 ± 1.864
3.866AlaGlu: 3.866 ± 1.864
1.289AlaPhe: 1.289 ± 2.609
5.155AlaGly: 5.155 ± 4.339
3.866AlaHis: 3.866 ± 5.6
1.289AlaIle: 1.289 ± 0.659
6.443AlaLys: 6.443 ± 3.295
6.443AlaLeu: 6.443 ± 3.99
0.0AlaMet: 0.0 ± 0.0
2.577AlaAsn: 2.577 ± 1.479
1.289AlaPro: 1.289 ± 0.659
6.443AlaGln: 6.443 ± 1.883
2.577AlaArg: 2.577 ± 1.318
9.021AlaSer: 9.021 ± 4.562
5.155AlaThr: 5.155 ± 2.636
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
2.577AlaTyr: 2.577 ± 1.318
0.0AlaXaa: 0.0 ± 0.0
Cys
1.289CysAla: 1.289 ± 2.609
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.577CysIle: 2.577 ± 1.318
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.289CysAsn: 1.289 ± 1.864
0.0CysPro: 0.0 ± 0.0
1.289CysGln: 1.289 ± 2.609
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.289CysThr: 1.289 ± 2.609
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.289CysTyr: 1.289 ± 0.659
0.0CysXaa: 0.0 ± 0.0
Asp
2.577AspAla: 2.577 ± 1.318
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
3.866AspGlu: 3.866 ± 1.864
5.155AspPhe: 5.155 ± 1.959
5.155AspGly: 5.155 ± 4.339
2.577AspHis: 2.577 ± 1.318
3.866AspIle: 3.866 ± 1.977
0.0AspLys: 0.0 ± 0.0
5.155AspLeu: 5.155 ± 1.959
1.289AspMet: 1.289 ± 0.659
2.577AspAsn: 2.577 ± 1.318
5.155AspPro: 5.155 ± 1.763
1.289AspGln: 1.289 ± 1.864
2.577AspArg: 2.577 ± 1.318
1.289AspSer: 1.289 ± 0.659
6.443AspThr: 6.443 ± 3.99
0.0AspVal: 0.0 ± 0.0
1.289AspTrp: 1.289 ± 1.864
1.289AspTyr: 1.289 ± 0.659
0.0AspXaa: 0.0 ± 0.0
Glu
6.443GluAla: 6.443 ± 1.324
0.0GluCys: 0.0 ± 0.0
1.289GluAsp: 1.289 ± 2.609
9.021GluGlu: 9.021 ± 2.749
2.577GluPhe: 2.577 ± 2.169
3.866GluGly: 3.866 ± 7.827
1.289GluHis: 1.289 ± 0.659
1.289GluIle: 1.289 ± 0.659
2.577GluLys: 2.577 ± 3.257
6.443GluLeu: 6.443 ± 2.736
0.0GluMet: 0.0 ± 0.0
1.289GluAsn: 1.289 ± 1.864
2.577GluPro: 2.577 ± 1.479
0.0GluGln: 0.0 ± 0.0
1.289GluArg: 1.289 ± 0.659
3.866GluSer: 3.866 ± 1.331
3.866GluThr: 3.866 ± 1.977
0.0GluVal: 0.0 ± 0.0
2.577GluTrp: 2.577 ± 1.318
2.577GluTyr: 2.577 ± 1.318
0.0GluXaa: 0.0 ± 0.0
Phe
2.577PheAla: 2.577 ± 1.318
1.289PheCys: 1.289 ± 2.609
1.289PheAsp: 1.289 ± 0.659
1.289PheGlu: 1.289 ± 2.609
1.289PhePhe: 1.289 ± 2.609
1.289PheGly: 1.289 ± 0.659
0.0PheHis: 0.0 ± 0.0
1.289PheIle: 1.289 ± 0.659
2.577PheLys: 2.577 ± 2.169
0.0PheLeu: 0.0 ± 0.0
1.289PheMet: 1.289 ± 1.382
1.289PheAsn: 1.289 ± 0.659
1.289PhePro: 1.289 ± 2.609
2.577PheGln: 2.577 ± 1.479
1.289PheArg: 1.289 ± 0.659
5.155PheSer: 5.155 ± 2.636
2.577PheThr: 2.577 ± 1.318
1.289PheVal: 1.289 ± 0.659
1.289PheTrp: 1.289 ± 0.659
1.289PheTyr: 1.289 ± 0.659
0.0PheXaa: 0.0 ± 0.0
Gly
6.443GlyAla: 6.443 ± 6.913
0.0GlyCys: 0.0 ± 0.0
5.155GlyAsp: 5.155 ± 10.436
5.155GlyGlu: 5.155 ± 1.959
2.577GlyPhe: 2.577 ± 1.318
5.155GlyGly: 5.155 ± 2.636
2.577GlyHis: 2.577 ± 2.169
2.577GlyIle: 2.577 ± 1.318
1.289GlyLys: 1.289 ± 1.864
9.021GlyLeu: 9.021 ± 3.338
0.0GlyMet: 0.0 ± 0.618
2.577GlyAsn: 2.577 ± 1.318
3.866GlyPro: 3.866 ± 1.977
2.577GlyGln: 2.577 ± 1.318
1.289GlyArg: 1.289 ± 0.659
1.289GlySer: 1.289 ± 2.609
7.732GlyThr: 7.732 ± 3.859
1.289GlyVal: 1.289 ± 0.659
2.577GlyTrp: 2.577 ± 1.318
1.289GlyTyr: 1.289 ± 0.659
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.577HisAsp: 2.577 ± 1.318
1.289HisGlu: 1.289 ± 0.659
0.0HisPhe: 0.0 ± 0.0
1.289HisGly: 1.289 ± 1.864
0.0HisHis: 0.0 ± 0.0
2.577HisIle: 2.577 ± 1.479
5.155HisLys: 5.155 ± 2.636
2.577HisLeu: 2.577 ± 2.169
0.0HisMet: 0.0 ± 0.0
3.866HisAsn: 3.866 ± 1.864
6.443HisPro: 6.443 ± 1.883
1.289HisGln: 1.289 ± 1.864
1.289HisArg: 1.289 ± 0.659
1.289HisSer: 1.289 ± 0.659
2.577HisThr: 2.577 ± 1.479
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.289HisTyr: 1.289 ± 2.609
0.0HisXaa: 0.0 ± 0.0
Ile
2.577IleAla: 2.577 ± 1.318
0.0IleCys: 0.0 ± 0.0
1.289IleAsp: 1.289 ± 0.659
2.577IleGlu: 2.577 ± 2.169
0.0IlePhe: 0.0 ± 0.0
0.0IleGly: 0.0 ± 0.0
2.577IleHis: 2.577 ± 1.318
3.866IleIle: 3.866 ± 1.977
5.155IleLys: 5.155 ± 2.636
1.289IleLeu: 1.289 ± 0.659
1.289IleMet: 1.289 ± 0.659
1.289IleAsn: 1.289 ± 0.659
2.577IlePro: 2.577 ± 1.318
5.155IleGln: 5.155 ± 2.958
3.866IleArg: 3.866 ± 1.977
2.577IleSer: 2.577 ± 1.318
2.577IleThr: 2.577 ± 1.318
1.289IleVal: 1.289 ± 0.659
2.577IleTrp: 2.577 ± 1.318
1.289IleTyr: 1.289 ± 0.659
0.0IleXaa: 0.0 ± 0.0
Lys
1.289LysAla: 1.289 ± 0.659
2.577LysCys: 2.577 ± 2.169
2.577LysAsp: 2.577 ± 2.169
5.155LysGlu: 5.155 ± 3.977
0.0LysPhe: 0.0 ± 0.0
5.155LysGly: 5.155 ± 1.959
1.289LysHis: 1.289 ± 1.864
2.577LysIle: 2.577 ± 1.318
5.155LysLys: 5.155 ± 7.455
7.732LysLeu: 7.732 ± 2.233
2.577LysMet: 2.577 ± 1.397
0.0LysAsn: 0.0 ± 0.0
2.577LysPro: 2.577 ± 1.318
2.577LysGln: 2.577 ± 3.727
7.732LysArg: 7.732 ± 2.395
5.155LysSer: 5.155 ± 2.958
3.866LysThr: 3.866 ± 1.977
1.289LysVal: 1.289 ± 0.659
2.577LysTrp: 2.577 ± 1.318
1.289LysTyr: 1.289 ± 0.659
0.0LysXaa: 0.0 ± 0.0
Leu
7.732LeuAla: 7.732 ± 6.508
0.0LeuCys: 0.0 ± 0.0
1.289LeuAsp: 1.289 ± 2.609
2.577LeuGlu: 2.577 ± 3.727
5.155LeuPhe: 5.155 ± 2.636
5.155LeuGly: 5.155 ± 1.763
3.866LeuHis: 3.866 ± 1.977
2.577LeuIle: 2.577 ± 3.257
0.0LeuLys: 0.0 ± 0.0
10.309LeuLeu: 10.309 ± 5.803
0.0LeuMet: 0.0 ± 0.0
2.577LeuAsn: 2.577 ± 1.318
1.289LeuPro: 1.289 ± 0.659
11.598LeuGln: 11.598 ± 4.185
2.577LeuArg: 2.577 ± 1.318
6.443LeuSer: 6.443 ± 1.324
9.021LeuThr: 9.021 ± 0.437
2.577LeuVal: 2.577 ± 1.318
5.155LeuTrp: 5.155 ± 1.763
2.577LeuTyr: 2.577 ± 1.318
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.289MetGly: 1.289 ± 2.609
0.0MetHis: 0.0 ± 0.0
1.289MetIle: 1.289 ± 0.659
2.577MetLys: 2.577 ± 1.318
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.289MetPro: 1.289 ± 0.659
1.289MetGln: 1.289 ± 1.864
1.289MetArg: 1.289 ± 0.659
0.0MetSer: 0.0 ± 0.0
3.866MetThr: 3.866 ± 1.331
1.289MetVal: 1.289 ± 0.659
0.0MetTrp: 0.0 ± 0.0
1.289MetTyr: 1.289 ± 0.659
0.0MetXaa: 0.0 ± 0.0
Asn
2.577AsnAla: 2.577 ± 1.318
0.0AsnCys: 0.0 ± 0.0
3.866AsnAsp: 3.866 ± 1.977
1.289AsnGlu: 1.289 ± 0.659
1.289AsnPhe: 1.289 ± 0.659
0.0AsnGly: 0.0 ± 0.0
1.289AsnHis: 1.289 ± 1.864
0.0AsnIle: 0.0 ± 0.0
1.289AsnLys: 1.289 ± 0.659
5.155AsnLeu: 5.155 ± 2.636
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.289AsnPro: 1.289 ± 0.659
1.289AsnGln: 1.289 ± 1.864
2.577AsnArg: 2.577 ± 1.318
3.866AsnSer: 3.866 ± 2.605
2.577AsnThr: 2.577 ± 1.479
2.577AsnVal: 2.577 ± 1.318
1.289AsnTrp: 1.289 ± 1.864
1.289AsnTyr: 1.289 ± 0.659
0.0AsnXaa: 0.0 ± 0.0
Pro
7.732ProAla: 7.732 ± 2.233
0.0ProCys: 0.0 ± 0.0
7.732ProAsp: 7.732 ± 3.955
5.155ProGlu: 5.155 ± 1.959
0.0ProPhe: 0.0 ± 0.0
0.0ProGly: 0.0 ± 0.0
1.289ProHis: 1.289 ± 0.659
3.866ProIle: 3.866 ± 1.977
6.443ProLys: 6.443 ± 1.324
1.289ProLeu: 1.289 ± 1.864
0.0ProMet: 0.0 ± 0.0
2.577ProAsn: 2.577 ± 1.318
6.443ProPro: 6.443 ± 1.324
3.866ProGln: 3.866 ± 1.331
0.0ProArg: 0.0 ± 0.0
3.866ProSer: 3.866 ± 1.977
1.289ProThr: 1.289 ± 0.659
2.577ProVal: 2.577 ± 3.257
1.289ProTrp: 1.289 ± 0.659
2.577ProTyr: 2.577 ± 1.318
0.0ProXaa: 0.0 ± 0.0
Gln
2.577GlnAla: 2.577 ± 1.318
0.0GlnCys: 0.0 ± 0.0
1.289GlnAsp: 1.289 ± 0.659
1.289GlnGlu: 1.289 ± 0.659
3.866GlnPhe: 3.866 ± 1.331
2.577GlnGly: 2.577 ± 1.479
3.866GlnHis: 3.866 ± 1.331
2.577GlnIle: 2.577 ± 1.318
7.732GlnLys: 7.732 ± 4.437
5.155GlnLeu: 5.155 ± 1.491
1.289GlnMet: 1.289 ± 0.659
1.289GlnAsn: 1.289 ± 1.864
2.577GlnPro: 2.577 ± 1.479
3.866GlnGln: 3.866 ± 3.3
3.866GlnArg: 3.866 ± 1.331
5.155GlnSer: 5.155 ± 3.977
5.155GlnThr: 5.155 ± 5.151
3.866GlnVal: 3.866 ± 1.977
2.577GlnTrp: 2.577 ± 1.318
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.866ArgAla: 3.866 ± 1.331
0.0ArgCys: 0.0 ± 0.0
1.289ArgAsp: 1.289 ± 0.659
1.289ArgGlu: 1.289 ± 0.659
2.577ArgPhe: 2.577 ± 1.318
3.866ArgGly: 3.866 ± 1.977
1.289ArgHis: 1.289 ± 0.659
2.577ArgIle: 2.577 ± 1.318
5.155ArgLys: 5.155 ± 1.491
3.866ArgLeu: 3.866 ± 1.977
1.289ArgMet: 1.289 ± 0.659
2.577ArgAsn: 2.577 ± 1.318
2.577ArgPro: 2.577 ± 1.318
0.0ArgGln: 0.0 ± 0.0
23.196ArgArg: 23.196 ± 8.371
2.577ArgSer: 2.577 ± 1.479
3.866ArgThr: 3.866 ± 1.977
2.577ArgVal: 2.577 ± 1.479
3.866ArgTrp: 3.866 ± 1.331
6.443ArgTyr: 6.443 ± 1.883
0.0ArgXaa: 0.0 ± 0.0
Ser
3.866SerAla: 3.866 ± 1.331
0.0SerCys: 0.0 ± 0.0
2.577SerAsp: 2.577 ± 1.479
7.732SerGlu: 7.732 ± 2.395
2.577SerPhe: 2.577 ± 2.169
9.021SerGly: 9.021 ± 6.454
2.577SerHis: 2.577 ± 1.318
1.289SerIle: 1.289 ± 0.659
3.866SerLys: 3.866 ± 2.605
3.866SerLeu: 3.866 ± 1.977
2.577SerMet: 2.577 ± 1.479
2.577SerAsn: 2.577 ± 1.318
2.577SerPro: 2.577 ± 3.257
2.577SerGln: 2.577 ± 1.479
3.866SerArg: 3.866 ± 1.331
14.175SerSer: 14.175 ± 9.452
6.443SerThr: 6.443 ± 3.338
5.155SerVal: 5.155 ± 1.491
1.289SerTrp: 1.289 ± 0.659
2.577SerTyr: 2.577 ± 1.479
0.0SerXaa: 0.0 ± 0.0
Thr
3.866ThrAla: 3.866 ± 2.605
1.289ThrCys: 1.289 ± 2.609
9.021ThrAsp: 9.021 ± 2.749
0.0ThrGlu: 0.0 ± 0.0
0.0ThrPhe: 0.0 ± 0.0
9.021ThrGly: 9.021 ± 2.689
2.577ThrHis: 2.577 ± 1.479
3.866ThrIle: 3.866 ± 1.977
6.443ThrLys: 6.443 ± 3.99
5.155ThrLeu: 5.155 ± 4.339
0.0ThrMet: 0.0 ± 0.0
3.866ThrAsn: 3.866 ± 1.331
5.155ThrPro: 5.155 ± 1.491
5.155ThrGln: 5.155 ± 1.491
5.155ThrArg: 5.155 ± 2.958
3.866ThrSer: 3.866 ± 1.331
5.155ThrThr: 5.155 ± 1.763
2.577ThrVal: 2.577 ± 1.318
2.577ThrTrp: 2.577 ± 1.318
1.289ThrTyr: 1.289 ± 0.659
0.0ThrXaa: 0.0 ± 0.0
Val
3.866ValAla: 3.866 ± 1.331
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
0.0ValGlu: 0.0 ± 0.0
0.0ValPhe: 0.0 ± 0.0
3.866ValGly: 3.866 ± 1.977
0.0ValHis: 0.0 ± 0.0
1.289ValIle: 1.289 ± 0.659
0.0ValLys: 0.0 ± 0.0
3.866ValLeu: 3.866 ± 1.977
1.289ValMet: 1.289 ± 0.659
0.0ValAsn: 0.0 ± 0.0
2.577ValPro: 2.577 ± 2.169
2.577ValGln: 2.577 ± 1.479
3.866ValArg: 3.866 ± 1.331
1.289ValSer: 1.289 ± 0.659
1.289ValThr: 1.289 ± 0.659
0.0ValVal: 0.0 ± 0.0
2.577ValTrp: 2.577 ± 1.318
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
3.866TrpAla: 3.866 ± 2.605
1.289TrpCys: 1.289 ± 0.659
5.155TrpAsp: 5.155 ± 1.491
1.289TrpGlu: 1.289 ± 0.659
1.289TrpPhe: 1.289 ± 0.659
2.577TrpGly: 2.577 ± 1.318
0.0TrpHis: 0.0 ± 0.0
1.289TrpIle: 1.289 ± 0.659
0.0TrpLys: 0.0 ± 0.0
3.866TrpLeu: 3.866 ± 1.977
1.289TrpMet: 1.289 ± 0.659
0.0TrpAsn: 0.0 ± 0.0
1.289TrpPro: 1.289 ± 0.659
2.577TrpGln: 2.577 ± 1.318
2.577TrpArg: 2.577 ± 1.318
5.155TrpSer: 5.155 ± 1.959
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
2.577TrpTyr: 2.577 ± 1.318
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.289TyrCys: 1.289 ± 0.659
1.289TyrAsp: 1.289 ± 0.659
0.0TyrGlu: 0.0 ± 0.0
2.577TyrPhe: 2.577 ± 1.318
1.289TyrGly: 1.289 ± 0.659
2.577TyrHis: 2.577 ± 1.318
1.289TyrIle: 1.289 ± 0.659
1.289TyrLys: 1.289 ± 1.864
1.289TyrLeu: 1.289 ± 0.659
0.0TyrMet: 0.0 ± 0.0
1.289TyrAsn: 1.289 ± 0.659
5.155TyrPro: 5.155 ± 2.636
2.577TyrGln: 2.577 ± 1.318
3.866TyrArg: 3.866 ± 1.977
5.155TyrSer: 5.155 ± 1.491
1.289TyrThr: 1.289 ± 0.659
0.0TyrVal: 0.0 ± 0.0
2.577TyrTrp: 2.577 ± 2.169
1.289TyrTyr: 1.289 ± 0.659
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (777 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski