Amino acid dipepetide frequency for Microvirga ossetica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.321AlaAla: 15.321 ± 0.118	1.073AlaCys: 1.073 ± 0.021	6.119AlaAsp: 6.119 ± 0.056	7.252AlaGlu: 7.252 ± 0.064	4.459AlaPhe: 4.459 ± 0.048	9.683AlaGly: 9.683 ± 0.071	2.291AlaHis: 2.291 ± 0.031	6.431AlaIle: 6.431 ± 0.054	4.064AlaLys: 4.064 ± 0.053	12.895AlaLeu: 12.895 ± 0.093	3.297AlaMet: 3.297 ± 0.035	2.762AlaAsn: 2.762 ± 0.034	5.09AlaPro: 5.09 ± 0.054	4.07AlaGln: 4.07 ± 0.045	8.203AlaArg: 8.203 ± 0.07	6.513AlaSer: 6.513 ± 0.053	5.77AlaThr: 5.77 ± 0.05	8.689AlaVal: 8.689 ± 0.068	1.514AlaTrp: 1.514 ± 0.026	2.648AlaTyr: 2.648 ± 0.031	0.0AlaXaa: 0.0 ± 0.0
Cys	0.876CysAla: 0.876 ± 0.018	0.136CysCys: 0.136 ± 0.009	0.488CysAsp: 0.488 ± 0.014	0.445CysGlu: 0.445 ± 0.014	0.3CysPhe: 0.3 ± 0.011	0.822CysGly: 0.822 ± 0.02	0.235CysHis: 0.235 ± 0.01	0.398CysIle: 0.398 ± 0.015	0.194CysLys: 0.194 ± 0.009	0.853CysLeu: 0.853 ± 0.022	0.161CysMet: 0.161 ± 0.009	0.198CysAsn: 0.198 ± 0.008	0.459CysPro: 0.459 ± 0.015	0.24CysGln: 0.24 ± 0.01	0.71CysArg: 0.71 ± 0.017	0.469CysSer: 0.469 ± 0.014	0.434CysThr: 0.434 ± 0.014	0.562CysVal: 0.562 ± 0.016	0.115CysTrp: 0.115 ± 0.007	0.181CysTyr: 0.181 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.265AspAla: 6.265 ± 0.052	0.414AspCys: 0.414 ± 0.013	2.98AspAsp: 2.98 ± 0.047	3.696AspGlu: 3.696 ± 0.044	2.011AspPhe: 2.011 ± 0.03	4.969AspGly: 4.969 ± 0.066	1.221AspHis: 1.221 ± 0.023	2.812AspIle: 2.812 ± 0.043	1.719AspLys: 1.719 ± 0.032	6.143AspLeu: 6.143 ± 0.056	1.163AspMet: 1.163 ± 0.021	1.252AspAsn: 1.252 ± 0.025	3.64AspPro: 3.64 ± 0.044	1.826AspGln: 1.826 ± 0.03	4.438AspArg: 4.438 ± 0.045	2.087AspSer: 2.087 ± 0.032	2.595AspThr: 2.595 ± 0.043	4.169AspVal: 4.169 ± 0.042	0.882AspTrp: 0.882 ± 0.019	1.343AspTyr: 1.343 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	7.953GluAla: 7.953 ± 0.073	0.373GluCys: 0.373 ± 0.013	2.801GluAsp: 2.801 ± 0.034	3.31GluGlu: 3.31 ± 0.049	1.784GluPhe: 1.784 ± 0.028	4.325GluGly: 4.325 ± 0.046	1.3GluHis: 1.3 ± 0.021	3.512GluIle: 3.512 ± 0.041	2.073GluLys: 2.073 ± 0.031	5.272GluLeu: 5.272 ± 0.054	1.477GluMet: 1.477 ± 0.027	1.48GluAsn: 1.48 ± 0.023	2.932GluPro: 2.932 ± 0.035	2.23GluGln: 2.23 ± 0.033	5.598GluArg: 5.598 ± 0.058	2.466GluSer: 2.466 ± 0.032	3.499GluThr: 3.499 ± 0.041	4.021GluVal: 4.021 ± 0.046	0.727GluTrp: 0.727 ± 0.018	0.973GluTyr: 0.973 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	4.241PheAla: 4.241 ± 0.043	0.358PheCys: 0.358 ± 0.011	2.466PheAsp: 2.466 ± 0.029	2.134PheGlu: 2.134 ± 0.031	1.361PhePhe: 1.361 ± 0.029	3.544PheGly: 3.544 ± 0.044	0.718PheHis: 0.718 ± 0.019	1.738PheIle: 1.738 ± 0.027	1.097PheLys: 1.097 ± 0.023	3.421PheLeu: 3.421 ± 0.039	0.806PheMet: 0.806 ± 0.019	0.995PheAsn: 0.995 ± 0.022	1.601PhePro: 1.601 ± 0.025	1.122PheGln: 1.122 ± 0.025	2.396PheArg: 2.396 ± 0.033	2.166PheSer: 2.166 ± 0.03	2.016PheThr: 2.016 ± 0.03	2.881PheVal: 2.881 ± 0.032	0.561PheTrp: 0.561 ± 0.017	0.913PheTyr: 0.913 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	8.452GlyAla: 8.452 ± 0.072	0.781GlyCys: 0.781 ± 0.019	4.274GlyAsp: 4.274 ± 0.058	4.595GlyGlu: 4.595 ± 0.052	3.529GlyPhe: 3.529 ± 0.037	6.999GlyGly: 6.999 ± 0.084	1.915GlyHis: 1.915 ± 0.031	4.69GlyIle: 4.69 ± 0.043	3.023GlyLys: 3.023 ± 0.039	8.86GlyLeu: 8.86 ± 0.075	2.089GlyMet: 2.089 ± 0.031	2.311GlyAsn: 2.311 ± 0.055	3.61GlyPro: 3.61 ± 0.042	3.067GlyGln: 3.067 ± 0.035	6.248GlyArg: 6.248 ± 0.056	5.088GlySer: 5.088 ± 0.043	4.729GlyThr: 4.729 ± 0.064	5.637GlyVal: 5.637 ± 0.052	1.4GlyTrp: 1.4 ± 0.025	2.275GlyTyr: 2.275 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	2.305HisAla: 2.305 ± 0.033	0.23HisCys: 0.23 ± 0.01	1.26HisAsp: 1.26 ± 0.022	1.193HisGlu: 1.193 ± 0.022	0.829HisPhe: 0.829 ± 0.018	1.923HisGly: 1.923 ± 0.032	0.6HisHis: 0.6 ± 0.018	0.929HisIle: 0.929 ± 0.021	0.531HisLys: 0.531 ± 0.015	2.28HisLeu: 2.28 ± 0.034	0.481HisMet: 0.481 ± 0.014	0.472HisAsn: 0.472 ± 0.013	1.432HisPro: 1.432 ± 0.024	0.641HisGln: 0.641 ± 0.017	1.731HisArg: 1.731 ± 0.028	1.008HisSer: 1.008 ± 0.02	0.855HisThr: 0.855 ± 0.02	1.536HisVal: 1.536 ± 0.027	0.36HisTrp: 0.36 ± 0.013	0.531HisTyr: 0.531 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	6.984IleAla: 6.984 ± 0.055	0.507IleCys: 0.507 ± 0.016	3.44IleAsp: 3.44 ± 0.042	3.629IleGlu: 3.629 ± 0.047	1.638IlePhe: 1.638 ± 0.026	5.06IleGly: 5.06 ± 0.046	0.99IleHis: 0.99 ± 0.022	2.191IleIle: 2.191 ± 0.034	1.463IleLys: 1.463 ± 0.024	4.947IleLeu: 4.947 ± 0.055	1.026IleMet: 1.026 ± 0.019	1.276IleAsn: 1.276 ± 0.026	2.49IlePro: 2.49 ± 0.038	1.437IleGln: 1.437 ± 0.024	3.606IleArg: 3.606 ± 0.04	2.756IleSer: 2.756 ± 0.035	2.718IleThr: 2.718 ± 0.035	4.567IleVal: 4.567 ± 0.044	0.618IleTrp: 0.618 ± 0.013	1.079IleTyr: 1.079 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	4.478LysAla: 4.478 ± 0.053	0.173LysCys: 0.173 ± 0.009	1.899LysAsp: 1.899 ± 0.034	1.711LysGlu: 1.711 ± 0.033	0.825LysPhe: 0.825 ± 0.019	2.781LysGly: 2.781 ± 0.038	0.679LysHis: 0.679 ± 0.015	1.637LysIle: 1.637 ± 0.03	1.195LysLys: 1.195 ± 0.03	3.227LysLeu: 3.227 ± 0.04	0.668LysMet: 0.668 ± 0.019	0.857LysAsn: 0.857 ± 0.022	2.169LysPro: 2.169 ± 0.031	1.046LysGln: 1.046 ± 0.019	2.501LysArg: 2.501 ± 0.039	1.833LysSer: 1.833 ± 0.027	1.913LysThr: 1.913 ± 0.031	2.532LysVal: 2.532 ± 0.042	0.367LysTrp: 0.367 ± 0.013	0.569LysTyr: 0.569 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	12.973LeuAla: 12.973 ± 0.083	0.878LeuCys: 0.878 ± 0.02	5.973LeuAsp: 5.973 ± 0.047	5.424LeuGlu: 5.424 ± 0.056	3.566LeuPhe: 3.566 ± 0.046	8.293LeuGly: 8.293 ± 0.066	1.976LeuHis: 1.976 ± 0.026	5.112LeuIle: 5.112 ± 0.053	3.85LeuLys: 3.85 ± 0.046	9.662LeuLeu: 9.662 ± 0.103	2.305LeuMet: 2.305 ± 0.035	2.685LeuAsn: 2.685 ± 0.035	5.545LeuPro: 5.545 ± 0.05	3.052LeuGln: 3.052 ± 0.037	7.232LeuArg: 7.232 ± 0.062	6.744LeuSer: 6.744 ± 0.051	5.661LeuThr: 5.661 ± 0.054	7.929LeuVal: 7.929 ± 0.071	1.253LeuTrp: 1.253 ± 0.024	2.094LeuTyr: 2.094 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.957MetAla: 2.957 ± 0.036	0.131MetCys: 0.131 ± 0.007	1.072MetAsp: 1.072 ± 0.022	1.067MetGlu: 1.067 ± 0.02	0.652MetPhe: 0.652 ± 0.017	1.66MetGly: 1.66 ± 0.029	0.439MetHis: 0.439 ± 0.013	1.318MetIle: 1.318 ± 0.025	0.991MetLys: 0.991 ± 0.021	2.357MetLeu: 2.357 ± 0.034	0.625MetMet: 0.625 ± 0.017	0.78MetAsn: 0.78 ± 0.018	1.475MetPro: 1.475 ± 0.023	0.776MetGln: 0.776 ± 0.02	1.868MetArg: 1.868 ± 0.026	1.587MetSer: 1.587 ± 0.026	1.819MetThr: 1.819 ± 0.026	1.561MetVal: 1.561 ± 0.025	0.199MetTrp: 0.199 ± 0.009	0.291MetTyr: 0.291 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.018AsnAla: 3.018 ± 0.032	0.196AsnCys: 0.196 ± 0.009	1.559AsnAsp: 1.559 ± 0.038	1.31AsnGlu: 1.31 ± 0.025	0.862AsnPhe: 0.862 ± 0.02	2.412AsnGly: 2.412 ± 0.043	0.487AsnHis: 0.487 ± 0.015	1.245AsnIle: 1.245 ± 0.028	0.723AsnLys: 0.723 ± 0.019	2.742AsnLeu: 2.742 ± 0.032	0.548AsnMet: 0.548 ± 0.017	0.701AsnAsn: 0.701 ± 0.019	1.859AsnPro: 1.859 ± 0.031	0.807AsnGln: 0.807 ± 0.019	1.852AsnArg: 1.852 ± 0.027	1.279AsnSer: 1.279 ± 0.022	1.277AsnThr: 1.277 ± 0.025	1.954AsnVal: 1.954 ± 0.033	0.395AsnTrp: 0.395 ± 0.013	0.627AsnTyr: 0.627 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.857ProAla: 5.857 ± 0.058	0.33ProCys: 0.33 ± 0.012	3.635ProAsp: 3.635 ± 0.044	3.728ProGlu: 3.728 ± 0.047	2.001ProPhe: 2.001 ± 0.028	4.458ProGly: 4.458 ± 0.042	1.15ProHis: 1.15 ± 0.021	2.453ProIle: 2.453 ± 0.033	1.86ProLys: 1.86 ± 0.034	4.76ProLeu: 4.76 ± 0.043	1.201ProMet: 1.201 ± 0.022	1.499ProAsn: 1.499 ± 0.026	2.728ProPro: 2.728 ± 0.04	1.813ProGln: 1.813 ± 0.03	2.995ProArg: 2.995 ± 0.041	3.294ProSer: 3.294 ± 0.035	2.687ProThr: 2.687 ± 0.036	4.254ProVal: 4.254 ± 0.045	0.757ProTrp: 0.757 ± 0.019	1.213ProTyr: 1.213 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	4.494GlnAla: 4.494 ± 0.048	0.222GlnCys: 0.222 ± 0.01	1.741GlnAsp: 1.741 ± 0.03	1.83GlnGlu: 1.83 ± 0.025	1.044GlnPhe: 1.044 ± 0.02	2.638GlnGly: 2.638 ± 0.031	0.739GlnHis: 0.739 ± 0.021	1.856GlnIle: 1.856 ± 0.027	1.092GlnLys: 1.092 ± 0.024	2.813GlnLeu: 2.813 ± 0.039	0.824GlnMet: 0.824 ± 0.019	0.879GlnAsn: 0.879 ± 0.02	1.86GlnPro: 1.86 ± 0.026	1.309GlnGln: 1.309 ± 0.025	2.688GlnArg: 2.688 ± 0.036	1.862GlnSer: 1.862 ± 0.027	1.826GlnThr: 1.826 ± 0.029	2.506GlnVal: 2.506 ± 0.031	0.418GlnTrp: 0.418 ± 0.012	0.622GlnTyr: 0.622 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	7.567ArgAla: 7.567 ± 0.055	0.594ArgCys: 0.594 ± 0.018	3.954ArgAsp: 3.954 ± 0.043	4.599ArgGlu: 4.599 ± 0.055	3.034ArgPhe: 3.034 ± 0.038	4.858ArgGly: 4.858 ± 0.047	1.855ArgHis: 1.855 ± 0.03	4.342ArgIle: 4.342 ± 0.037	2.412ArgLys: 2.412 ± 0.034	8.341ArgLeu: 8.341 ± 0.081	1.909ArgMet: 1.909 ± 0.025	1.954ArgAsn: 1.954 ± 0.029	3.705ArgPro: 3.705 ± 0.041	2.939ArgGln: 2.939 ± 0.042	6.353ArgArg: 6.353 ± 0.074	4.316ArgSer: 4.316 ± 0.039	3.694ArgThr: 3.694 ± 0.04	5.015ArgVal: 5.015 ± 0.048	1.178ArgTrp: 1.178 ± 0.026	1.81ArgTyr: 1.81 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	5.957SerAla: 5.957 ± 0.054	0.444SerCys: 0.444 ± 0.016	3.069SerAsp: 3.069 ± 0.036	2.958SerGlu: 2.958 ± 0.038	2.359SerPhe: 2.359 ± 0.034	5.543SerGly: 5.543 ± 0.056	1.214SerHis: 1.214 ± 0.023	2.956SerIle: 2.956 ± 0.037	1.684SerLys: 1.684 ± 0.032	6.02SerLeu: 6.02 ± 0.056	1.318SerMet: 1.318 ± 0.026	1.415SerAsn: 1.415 ± 0.028	3.104SerPro: 3.104 ± 0.035	1.795SerGln: 1.795 ± 0.029	4.039SerArg: 4.039 ± 0.045	3.254SerSer: 3.254 ± 0.041	2.913SerThr: 2.913 ± 0.036	4.072SerVal: 4.072 ± 0.047	0.828SerTrp: 0.828 ± 0.018	1.395SerTyr: 1.395 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	5.93ThrAla: 5.93 ± 0.048	0.435ThrCys: 0.435 ± 0.016	2.751ThrAsp: 2.751 ± 0.042	2.712ThrGlu: 2.712 ± 0.03	2.125ThrPhe: 2.125 ± 0.028	5.007ThrGly: 5.007 ± 0.051	1.06ThrHis: 1.06 ± 0.024	3.152ThrIle: 3.152 ± 0.034	1.651ThrLys: 1.651 ± 0.029	5.941ThrLeu: 5.941 ± 0.058	1.206ThrMet: 1.206 ± 0.02	1.32ThrAsn: 1.32 ± 0.026	3.189ThrPro: 3.189 ± 0.04	1.503ThrGln: 1.503 ± 0.026	3.461ThrArg: 3.461 ± 0.04	2.989ThrSer: 2.989 ± 0.037	2.832ThrThr: 2.832 ± 0.043	4.356ThrVal: 4.356 ± 0.05	0.785ThrTrp: 0.785 ± 0.019	1.314ThrTyr: 1.314 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	8.738ValAla: 8.738 ± 0.063	0.628ValCys: 0.628 ± 0.015	4.043ValAsp: 4.043 ± 0.048	4.674ValGlu: 4.674 ± 0.049	2.712ValPhe: 2.712 ± 0.035	5.584ValGly: 5.584 ± 0.055	1.428ValHis: 1.428 ± 0.025	4.008ValIle: 4.008 ± 0.042	2.315ValLys: 2.315 ± 0.037	7.715ValLeu: 7.715 ± 0.069	1.799ValMet: 1.799 ± 0.03	1.971ValAsn: 1.971 ± 0.028	3.913ValPro: 3.913 ± 0.037	2.311ValGln: 2.311 ± 0.032	5.357ValArg: 5.357 ± 0.047	4.562ValSer: 4.562 ± 0.048	4.549ValThr: 4.549 ± 0.047	6.048ValVal: 6.048 ± 0.054	0.914ValTrp: 0.914 ± 0.019	1.538ValTyr: 1.538 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.287TrpAla: 1.287 ± 0.027	0.138TrpCys: 0.138 ± 0.008	0.677TrpAsp: 0.677 ± 0.017	0.571TrpGlu: 0.571 ± 0.016	0.56TrpPhe: 0.56 ± 0.016	0.894TrpGly: 0.894 ± 0.021	0.368TrpHis: 0.368 ± 0.011	0.76TrpIle: 0.76 ± 0.018	0.49TrpLys: 0.49 ± 0.015	1.718TrpLeu: 1.718 ± 0.025	0.343TrpMet: 0.343 ± 0.011	0.45TrpAsn: 0.45 ± 0.013	0.707TrpPro: 0.707 ± 0.017	0.592TrpGln: 0.592 ± 0.016	1.243TrpArg: 1.243 ± 0.023	0.899TrpSer: 0.899 ± 0.02	0.83TrpThr: 0.83 ± 0.019	0.831TrpVal: 0.831 ± 0.02	0.232TrpTrp: 0.232 ± 0.012	0.301TrpTyr: 0.301 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.491TyrAla: 2.491 ± 0.034	0.236TyrCys: 0.236 ± 0.01	1.426TyrAsp: 1.426 ± 0.028	1.269TyrGlu: 1.269 ± 0.023	0.886TyrPhe: 0.886 ± 0.018	2.119TyrGly: 2.119 ± 0.032	0.462TyrHis: 0.462 ± 0.012	0.883TyrIle: 0.883 ± 0.021	0.633TyrLys: 0.633 ± 0.017	2.238TyrLeu: 2.238 ± 0.03	0.377TyrMet: 0.377 ± 0.011	0.595TyrAsn: 0.595 ± 0.016	1.166TyrPro: 1.166 ± 0.024	0.687TyrGln: 0.687 ± 0.016	1.909TyrArg: 1.909 ± 0.03	1.163TyrSer: 1.163 ± 0.023	1.104TyrThr: 1.104 ± 0.023	1.687TyrVal: 1.687 ± 0.028	0.387TyrTrp: 0.387 ± 0.013	0.602TyrTyr: 0.602 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8355 proteins (2404899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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