Amino acid dipepetide frequency for Longimonas halophila

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.401AlaAla: 11.401 ± 0.15	0.898AlaCys: 0.898 ± 0.032	7.285AlaAsp: 7.285 ± 0.111	7.026AlaGlu: 7.026 ± 0.094	4.082AlaPhe: 4.082 ± 0.069	7.332AlaGly: 7.332 ± 0.122	2.845AlaHis: 2.845 ± 0.057	4.36AlaIle: 4.36 ± 0.082	1.933AlaLys: 1.933 ± 0.053	12.39AlaLeu: 12.39 ± 0.139	2.56AlaMet: 2.56 ± 0.059	2.906AlaAsn: 2.906 ± 0.054	6.021AlaPro: 6.021 ± 0.087	4.591AlaGln: 4.591 ± 0.078	6.589AlaArg: 6.589 ± 0.089	6.852AlaSer: 6.852 ± 0.102	6.526AlaThr: 6.526 ± 0.099	7.693AlaVal: 7.693 ± 0.108	1.551AlaTrp: 1.551 ± 0.04	3.09AlaTyr: 3.09 ± 0.06	0.0AlaXaa: 0.0 ± 0.0
Cys	0.723CysAla: 0.723 ± 0.028	0.112CysCys: 0.112 ± 0.012	0.411CysAsp: 0.411 ± 0.022	0.352CysGlu: 0.352 ± 0.019	0.233CysPhe: 0.233 ± 0.015	0.603CysGly: 0.603 ± 0.024	0.18CysHis: 0.18 ± 0.015	0.391CysIle: 0.391 ± 0.021	0.119CysLys: 0.119 ± 0.011	0.53CysLeu: 0.53 ± 0.02	0.134CysMet: 0.134 ± 0.012	0.228CysAsn: 0.228 ± 0.015	0.426CysPro: 0.426 ± 0.021	0.21CysGln: 0.21 ± 0.016	0.415CysArg: 0.415 ± 0.024	0.484CysSer: 0.484 ± 0.025	0.65CysThr: 0.65 ± 0.026	0.505CysVal: 0.505 ± 0.025	0.102CysTrp: 0.102 ± 0.01	0.185CysTyr: 0.185 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	9.552AspAla: 9.552 ± 0.129	0.324AspCys: 0.324 ± 0.018	5.142AspAsp: 5.142 ± 0.099	4.719AspGlu: 4.719 ± 0.078	2.185AspPhe: 2.185 ± 0.063	5.763AspGly: 5.763 ± 0.141	1.414AspHis: 1.414 ± 0.039	2.846AspIle: 2.846 ± 0.06	1.107AspLys: 1.107 ± 0.04	6.385AspLeu: 6.385 ± 0.099	1.247AspMet: 1.247 ± 0.037	1.651AspAsn: 1.651 ± 0.047	3.854AspPro: 3.854 ± 0.07	1.985AspGln: 1.985 ± 0.046	4.59AspArg: 4.59 ± 0.075	3.221AspSer: 3.221 ± 0.07	5.213AspThr: 5.213 ± 0.086	5.458AspVal: 5.458 ± 0.081	0.994AspTrp: 0.994 ± 0.034	1.784AspTyr: 1.784 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	8.766GluAla: 8.766 ± 0.109	0.28GluCys: 0.28 ± 0.016	3.787GluAsp: 3.787 ± 0.075	4.433GluGlu: 4.433 ± 0.094	1.37GluPhe: 1.37 ± 0.034	4.568GluGly: 4.568 ± 0.07	1.803GluHis: 1.803 ± 0.047	2.699GluIle: 2.699 ± 0.061	1.519GluLys: 1.519 ± 0.054	5.19GluLeu: 5.19 ± 0.078	1.464GluMet: 1.464 ± 0.043	1.922GluAsn: 1.922 ± 0.049	2.938GluPro: 2.938 ± 0.06	3.26GluGln: 3.26 ± 0.064	5.805GluArg: 5.805 ± 0.092	3.666GluSer: 3.666 ± 0.054	3.972GluThr: 3.972 ± 0.066	4.416GluVal: 4.416 ± 0.077	0.728GluTrp: 0.728 ± 0.031	1.422GluTyr: 1.422 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.502PheAla: 3.502 ± 0.061	0.277PheCys: 0.277 ± 0.015	2.852PheAsp: 2.852 ± 0.056	2.468PheGlu: 2.468 ± 0.049	1.413PhePhe: 1.413 ± 0.046	3.05PheGly: 3.05 ± 0.066	0.636PheHis: 0.636 ± 0.022	1.473PheIle: 1.473 ± 0.043	0.657PheLys: 0.657 ± 0.027	2.844PheLeu: 2.844 ± 0.068	0.746PheMet: 0.746 ± 0.028	1.153PheAsn: 1.153 ± 0.035	1.423PhePro: 1.423 ± 0.039	1.232PheGln: 1.232 ± 0.035	2.0PheArg: 2.0 ± 0.044	2.312PheSer: 2.312 ± 0.057	2.298PheThr: 2.298 ± 0.053	2.809PheVal: 2.809 ± 0.057	0.518PheTrp: 0.518 ± 0.025	1.086PheTyr: 1.086 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	7.772GlyAla: 7.772 ± 0.131	0.759GlyCys: 0.759 ± 0.03	4.6GlyAsp: 4.6 ± 0.089	4.082GlyGlu: 4.082 ± 0.071	2.892GlyPhe: 2.892 ± 0.064	6.363GlyGly: 6.363 ± 0.135	1.727GlyHis: 1.727 ± 0.046	3.865GlyIle: 3.865 ± 0.069	1.585GlyLys: 1.585 ± 0.05	7.212GlyLeu: 7.212 ± 0.093	1.752GlyMet: 1.752 ± 0.045	2.284GlyAsn: 2.284 ± 0.084	3.323GlyPro: 3.323 ± 0.059	2.694GlyGln: 2.694 ± 0.055	4.695GlyArg: 4.695 ± 0.075	4.643GlySer: 4.643 ± 0.081	6.297GlyThr: 6.297 ± 0.123	5.608GlyVal: 5.608 ± 0.084	1.181GlyTrp: 1.181 ± 0.038	2.45GlyTyr: 2.45 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.722HisAla: 2.722 ± 0.06	0.203HisCys: 0.203 ± 0.015	1.827HisAsp: 1.827 ± 0.045	1.553HisGlu: 1.553 ± 0.045	0.785HisPhe: 0.785 ± 0.028	1.843HisGly: 1.843 ± 0.044	0.737HisHis: 0.737 ± 0.028	1.178HisIle: 1.178 ± 0.035	0.422HisLys: 0.422 ± 0.023	2.449HisLeu: 2.449 ± 0.059	0.434HisMet: 0.434 ± 0.018	0.681HisAsn: 0.681 ± 0.027	1.774HisPro: 1.774 ± 0.044	0.795HisGln: 0.795 ± 0.028	1.72HisArg: 1.72 ± 0.046	1.081HisSer: 1.081 ± 0.036	1.72HisThr: 1.72 ± 0.039	2.003HisVal: 2.003 ± 0.049	0.343HisTrp: 0.343 ± 0.017	0.673HisTyr: 0.673 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	4.897IleAla: 4.897 ± 0.069	0.358IleCys: 0.358 ± 0.018	3.836IleAsp: 3.836 ± 0.061	3.46IleGlu: 3.46 ± 0.066	1.332IlePhe: 1.332 ± 0.037	3.87IleGly: 3.87 ± 0.073	0.936IleHis: 0.936 ± 0.031	1.789IleIle: 1.789 ± 0.049	0.953IleLys: 0.953 ± 0.033	3.144IleLeu: 3.144 ± 0.057	0.806IleMet: 0.806 ± 0.027	1.422IleAsn: 1.422 ± 0.037	2.277IlePro: 2.277 ± 0.046	1.729IleGln: 1.729 ± 0.04	3.048IleArg: 3.048 ± 0.059	2.329IleSer: 2.329 ± 0.054	3.002IleThr: 3.002 ± 0.063	3.344IleVal: 3.344 ± 0.064	0.479IleTrp: 0.479 ± 0.021	1.177IleTyr: 1.177 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	2.167LysAla: 2.167 ± 0.052	0.11LysCys: 0.11 ± 0.012	1.148LysAsp: 1.148 ± 0.039	1.468LysGlu: 1.468 ± 0.05	0.43LysPhe: 0.43 ± 0.019	1.469LysGly: 1.469 ± 0.048	0.578LysHis: 0.578 ± 0.024	0.876LysIle: 0.876 ± 0.032	0.932LysLys: 0.932 ± 0.045	1.732LysLeu: 1.732 ± 0.047	0.504LysMet: 0.504 ± 0.027	0.665LysAsn: 0.665 ± 0.027	1.015LysPro: 1.015 ± 0.033	1.054LysGln: 1.054 ± 0.039	1.888LysArg: 1.888 ± 0.057	1.3LysSer: 1.3 ± 0.041	1.345LysThr: 1.345 ± 0.042	1.313LysVal: 1.313 ± 0.045	0.23LysTrp: 0.23 ± 0.017	0.563LysTyr: 0.563 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	9.222LeuAla: 9.222 ± 0.108	0.718LeuCys: 0.718 ± 0.031	6.805LeuAsp: 6.805 ± 0.098	5.107LeuGlu: 5.107 ± 0.083	3.519LeuPhe: 3.519 ± 0.07	6.786LeuGly: 6.786 ± 0.096	2.703LeuHis: 2.703 ± 0.063	4.156LeuIle: 4.156 ± 0.078	2.207LeuLys: 2.207 ± 0.057	9.254LeuLeu: 9.254 ± 0.129	2.165LeuMet: 2.165 ± 0.049	3.158LeuAsn: 3.158 ± 0.062	5.108LeuPro: 5.108 ± 0.085	3.968LeuGln: 3.968 ± 0.07	7.178LeuArg: 7.178 ± 0.091	6.16LeuSer: 6.16 ± 0.092	5.812LeuThr: 5.812 ± 0.072	6.639LeuVal: 6.639 ± 0.099	1.189LeuTrp: 1.189 ± 0.037	2.666LeuTyr: 2.666 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.399MetAla: 2.399 ± 0.056	0.133MetCys: 0.133 ± 0.011	1.241MetAsp: 1.241 ± 0.036	1.253MetGlu: 1.253 ± 0.039	0.482MetPhe: 0.482 ± 0.026	1.587MetGly: 1.587 ± 0.045	0.635MetHis: 0.635 ± 0.026	0.901MetIle: 0.901 ± 0.03	0.602MetLys: 0.602 ± 0.026	2.132MetLeu: 2.132 ± 0.054	0.547MetMet: 0.547 ± 0.026	0.717MetAsn: 0.717 ± 0.024	1.484MetPro: 1.484 ± 0.041	1.226MetGln: 1.226 ± 0.038	1.787MetArg: 1.787 ± 0.043	1.331MetSer: 1.331 ± 0.033	1.301MetThr: 1.301 ± 0.035	1.358MetVal: 1.358 ± 0.039	0.23MetTrp: 0.23 ± 0.016	0.51MetTyr: 0.51 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.623AsnAla: 3.623 ± 0.07	0.181AsnCys: 0.181 ± 0.013	2.178AsnAsp: 2.178 ± 0.049	2.181AsnGlu: 2.181 ± 0.046	0.879AsnPhe: 0.879 ± 0.033	2.639AsnGly: 2.639 ± 0.065	0.566AsnHis: 0.566 ± 0.021	1.215AsnIle: 1.215 ± 0.037	0.593AsnLys: 0.593 ± 0.026	2.436AsnLeu: 2.436 ± 0.055	0.573AsnMet: 0.573 ± 0.023	1.005AsnAsn: 1.005 ± 0.044	2.003AsnPro: 2.003 ± 0.051	1.085AsnGln: 1.085 ± 0.036	2.019AsnArg: 2.019 ± 0.043	1.365AsnSer: 1.365 ± 0.056	2.033AsnThr: 2.033 ± 0.06	2.362AsnVal: 2.362 ± 0.059	0.43AsnTrp: 0.43 ± 0.022	0.832AsnTyr: 0.832 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	5.179ProAla: 5.179 ± 0.077	0.291ProCys: 0.291 ± 0.017	4.976ProAsp: 4.976 ± 0.077	4.339ProGlu: 4.339 ± 0.074	1.934ProPhe: 1.934 ± 0.044	3.715ProGly: 3.715 ± 0.067	1.416ProHis: 1.416 ± 0.04	2.104ProIle: 2.104 ± 0.046	1.057ProLys: 1.057 ± 0.033	4.698ProLeu: 4.698 ± 0.072	1.108ProMet: 1.108 ± 0.034	1.963ProAsn: 1.963 ± 0.049	3.067ProPro: 3.067 ± 0.064	1.712ProGln: 1.712 ± 0.046	2.784ProArg: 2.784 ± 0.057	3.505ProSer: 3.505 ± 0.06	3.513ProThr: 3.513 ± 0.066	4.26ProVal: 4.26 ± 0.07	0.638ProTrp: 0.638 ± 0.027	1.592ProTyr: 1.592 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	4.636GlnAla: 4.636 ± 0.078	0.211GlnCys: 0.211 ± 0.014	2.116GlnAsp: 2.116 ± 0.048	2.368GlnGlu: 2.368 ± 0.056	1.372GlnPhe: 1.372 ± 0.034	2.689GlnGly: 2.689 ± 0.05	1.149GlnHis: 1.149 ± 0.034	1.732GlnIle: 1.732 ± 0.039	0.879GlnLys: 0.879 ± 0.033	3.372GlnLeu: 3.372 ± 0.063	0.935GlnMet: 0.935 ± 0.03	1.103GlnAsn: 1.103 ± 0.033	2.031GlnPro: 2.031 ± 0.046	2.132GlnGln: 2.132 ± 0.052	3.289GlnArg: 3.289 ± 0.061	2.378GlnSer: 2.378 ± 0.059	2.38GlnThr: 2.38 ± 0.052	2.862GlnVal: 2.862 ± 0.059	0.634GlnTrp: 0.634 ± 0.024	1.065GlnTyr: 1.065 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	6.738ArgAla: 6.738 ± 0.084	0.463ArgCys: 0.463 ± 0.026	4.065ArgAsp: 4.065 ± 0.065	3.971ArgGlu: 3.971 ± 0.078	2.896ArgPhe: 2.896 ± 0.06	4.002ArgGly: 4.002 ± 0.07	1.624ArgHis: 1.624 ± 0.049	3.893ArgIle: 3.893 ± 0.064	1.521ArgLys: 1.521 ± 0.047	6.891ArgLeu: 6.891 ± 0.099	1.677ArgMet: 1.677 ± 0.038	2.011ArgAsn: 2.011 ± 0.044	3.38ArgPro: 3.38 ± 0.058	2.535ArgGln: 2.535 ± 0.043	4.761ArgArg: 4.761 ± 0.085	4.286ArgSer: 4.286 ± 0.072	5.015ArgThr: 5.015 ± 0.081	4.883ArgVal: 4.883 ± 0.071	1.094ArgTrp: 1.094 ± 0.037	2.349ArgTyr: 2.349 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.037SerAla: 6.037 ± 0.087	0.354SerCys: 0.354 ± 0.018	4.416SerAsp: 4.416 ± 0.074	3.644SerGlu: 3.644 ± 0.061	2.339SerPhe: 2.339 ± 0.053	5.425SerGly: 5.425 ± 0.102	1.18SerHis: 1.18 ± 0.031	2.757SerIle: 2.757 ± 0.054	1.185SerLys: 1.185 ± 0.039	5.054SerLeu: 5.054 ± 0.08	1.451SerMet: 1.451 ± 0.04	2.019SerAsn: 2.019 ± 0.055	3.116SerPro: 3.116 ± 0.074	1.779SerGln: 1.779 ± 0.048	3.103SerArg: 3.103 ± 0.061	4.159SerSer: 4.159 ± 0.087	4.199SerThr: 4.199 ± 0.073	4.455SerVal: 4.455 ± 0.064	0.827SerTrp: 0.827 ± 0.031	1.83SerTyr: 1.83 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	6.869ThrAla: 6.869 ± 0.111	0.42ThrCys: 0.42 ± 0.018	4.566ThrAsp: 4.566 ± 0.088	3.961ThrGlu: 3.961 ± 0.068	2.503ThrPhe: 2.503 ± 0.059	5.309ThrGly: 5.309 ± 0.098	1.664ThrHis: 1.664 ± 0.039	3.093ThrIle: 3.093 ± 0.061	1.161ThrLys: 1.161 ± 0.034	7.287ThrLeu: 7.287 ± 0.087	1.174ThrMet: 1.174 ± 0.038	1.84ThrAsn: 1.84 ± 0.057	4.458ThrPro: 4.458 ± 0.071	2.273ThrGln: 2.273 ± 0.052	3.711ThrArg: 3.711 ± 0.067	3.654ThrSer: 3.654 ± 0.078	4.311ThrThr: 4.311 ± 0.069	5.54ThrVal: 5.54 ± 0.099	0.929ThrTrp: 0.929 ± 0.033	2.209ThrTyr: 2.209 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	7.396ValAla: 7.396 ± 0.099	0.584ValCys: 0.584 ± 0.023	5.231ValAsp: 5.231 ± 0.066	5.082ValGlu: 5.082 ± 0.081	2.572ValPhe: 2.572 ± 0.06	5.458ValGly: 5.458 ± 0.085	1.955ValHis: 1.955 ± 0.055	3.019ValIle: 3.019 ± 0.058	1.494ValLys: 1.494 ± 0.052	7.664ValLeu: 7.664 ± 0.107	1.524ValMet: 1.524 ± 0.039	2.068ValAsn: 2.068 ± 0.05	4.131ValPro: 4.131 ± 0.068	3.397ValGln: 3.397 ± 0.064	5.407ValArg: 5.407 ± 0.073	4.405ValSer: 4.405 ± 0.077	4.204ValThr: 4.204 ± 0.074	6.13ValVal: 6.13 ± 0.098	0.937ValTrp: 0.937 ± 0.037	2.001ValTyr: 2.001 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.322TrpAla: 1.322 ± 0.036	0.105TrpCys: 0.105 ± 0.011	0.728TrpAsp: 0.728 ± 0.029	0.584TrpGlu: 0.584 ± 0.028	0.438TrpPhe: 0.438 ± 0.02	1.024TrpGly: 1.024 ± 0.028	0.459TrpHis: 0.459 ± 0.025	0.716TrpIle: 0.716 ± 0.025	0.321TrpLys: 0.321 ± 0.015	1.242TrpLeu: 1.242 ± 0.041	0.535TrpMet: 0.535 ± 0.022	0.431TrpAsn: 0.431 ± 0.019	0.63TrpPro: 0.63 ± 0.024	0.626TrpGln: 0.626 ± 0.025	0.965TrpArg: 0.965 ± 0.028	0.887TrpSer: 0.887 ± 0.032	1.134TrpThr: 1.134 ± 0.042	0.878TrpVal: 0.878 ± 0.036	0.254TrpTrp: 0.254 ± 0.018	0.407TrpTyr: 0.407 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.01TyrAla: 3.01 ± 0.061	0.211TyrCys: 0.211 ± 0.015	2.225TyrAsp: 2.225 ± 0.053	1.957TyrGlu: 1.957 ± 0.047	1.095TyrPhe: 1.095 ± 0.038	2.29TyrGly: 2.29 ± 0.051	0.735TyrHis: 0.735 ± 0.027	1.13TyrIle: 1.13 ± 0.035	0.54TyrLys: 0.54 ± 0.026	2.613TyrLeu: 2.613 ± 0.064	0.52TyrMet: 0.52 ± 0.023	0.971TyrAsn: 0.971 ± 0.036	1.39TyrPro: 1.39 ± 0.037	1.051TyrGln: 1.051 ± 0.037	2.301TyrArg: 2.301 ± 0.054	1.312TyrSer: 1.312 ± 0.039	2.007TyrThr: 2.007 ± 0.051	2.141TyrVal: 2.141 ± 0.053	0.395TyrTrp: 0.395 ± 0.019	0.865TyrTyr: 0.865 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2920 proteins (1046801 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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