Amino acid dipepetide frequency for Sanxia Water Strider Virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.525AlaAla: 2.525 ± 0.737
0.505AlaCys: 0.505 ± 0.498
3.787AlaAsp: 3.787 ± 0.486
4.039AlaGlu: 4.039 ± 0.498
1.01AlaPhe: 1.01 ± 0.419
1.515AlaGly: 1.515 ± 0.586
1.01AlaHis: 1.01 ± 0.883
3.282AlaIle: 3.282 ± 1.276
2.777AlaLys: 2.777 ± 0.729
5.302AlaLeu: 5.302 ± 0.166
1.262AlaMet: 1.262 ± 1.419
3.03AlaAsn: 3.03 ± 0.921
1.262AlaPro: 1.262 ± 0.383
0.757AlaGln: 0.757 ± 0.527
2.525AlaArg: 2.525 ± 1.438
3.282AlaSer: 3.282 ± 1.29
2.272AlaThr: 2.272 ± 0.789
2.777AlaVal: 2.777 ± 0.195
0.757AlaTrp: 0.757 ± 0.5
2.272AlaTyr: 2.272 ± 0.159
0.0AlaXaa: 0.0 ± 0.0
Cys
1.01CysAla: 1.01 ± 0.307
1.01CysCys: 1.01 ± 0.995
1.01CysAsp: 1.01 ± 0.307
0.505CysGlu: 0.505 ± 0.498
0.505CysPhe: 0.505 ± 0.153
0.505CysGly: 0.505 ± 0.498
0.252CysHis: 0.252 ± 0.249
2.02CysIle: 2.02 ± 0.572
1.262CysLys: 1.262 ± 0.531
0.252CysLeu: 0.252 ± 0.15
1.01CysMet: 1.01 ± 0.577
0.505CysAsn: 0.505 ± 0.153
0.505CysPro: 0.505 ± 0.153
0.252CysGln: 0.252 ± 0.15
1.01CysArg: 1.01 ± 0.307
1.262CysSer: 1.262 ± 1.082
0.505CysThr: 0.505 ± 0.153
1.262CysVal: 1.262 ± 1.082
0.0CysTrp: 0.0 ± 0.0
0.252CysTyr: 0.252 ± 0.15
0.0CysXaa: 0.0 ± 0.0
Asp
1.767AspAla: 1.767 ± 0.25
0.505AspCys: 0.505 ± 0.498
5.807AspAsp: 5.807 ± 0.998
3.03AspGlu: 3.03 ± 0.715
2.777AspPhe: 2.777 ± 0.771
2.777AspGly: 2.777 ± 0.189
1.01AspHis: 1.01 ± 0.286
6.816AspIle: 6.816 ± 0.92
4.544AspLys: 4.544 ± 2.698
5.302AspLeu: 5.302 ± 1.318
2.02AspMet: 2.02 ± 0.351
5.807AspAsn: 5.807 ± 1.311
1.515AspPro: 1.515 ± 0.347
2.777AspGln: 2.777 ± 0.956
2.777AspArg: 2.777 ± 1.434
4.544AspSer: 4.544 ± 1.662
3.787AspThr: 3.787 ± 1.061
5.049AspVal: 5.049 ± 0.572
0.757AspTrp: 0.757 ± 0.174
3.282AspTyr: 3.282 ± 0.99
0.0AspXaa: 0.0 ± 0.0
Glu
2.525GluAla: 2.525 ± 1.371
0.0GluCys: 0.0 ± 0.0
2.525GluAsp: 2.525 ± 0.617
3.282GluGlu: 3.282 ± 0.563
3.282GluPhe: 3.282 ± 1.276
2.777GluGly: 2.777 ± 0.575
1.01GluHis: 1.01 ± 0.556
4.797GluIle: 4.797 ± 0.413
6.312GluLys: 6.312 ± 0.441
5.554GluLeu: 5.554 ± 1.973
3.282GluMet: 3.282 ± 0.678
4.039GluAsn: 4.039 ± 0.57
1.262GluPro: 1.262 ± 0.877
2.02GluGln: 2.02 ± 1.112
2.777GluArg: 2.777 ± 0.986
5.049GluSer: 5.049 ± 0.572
3.787GluThr: 3.787 ± 0.776
3.534GluVal: 3.534 ± 2.491
0.505GluTrp: 0.505 ± 0.153
2.02GluTyr: 2.02 ± 0.859
0.0GluXaa: 0.0 ± 0.0
Phe
3.282PheAla: 3.282 ± 0.622
0.757PheCys: 0.757 ± 0.174
2.525PheAsp: 2.525 ± 0.617
2.777PheGlu: 2.777 ± 0.569
2.02PhePhe: 2.02 ± 0.572
1.515PheGly: 1.515 ± 1.125
0.757PheHis: 0.757 ± 0.174
2.02PheIle: 2.02 ± 0.614
3.787PheLys: 3.787 ± 0.732
3.282PheLeu: 3.282 ± 1.817
1.262PheMet: 1.262 ± 0.297
4.292PheAsn: 4.292 ± 1.552
1.262PhePro: 1.262 ± 0.621
1.262PheGln: 1.262 ± 0.422
1.767PheArg: 1.767 ± 0.449
3.534PheSer: 3.534 ± 0.897
2.02PheThr: 2.02 ± 0.941
2.525PheVal: 2.525 ± 0.844
0.505PheTrp: 0.505 ± 0.498
3.03PheTyr: 3.03 ± 0.811
0.0PheXaa: 0.0 ± 0.0
Gly
2.02GlyAla: 2.02 ± 0.614
1.767GlyCys: 1.767 ± 0.68
2.525GlyAsp: 2.525 ± 0.617
2.777GlyGlu: 2.777 ± 0.575
2.525GlyPhe: 2.525 ± 0.617
1.515GlyGly: 1.515 ± 0.46
0.757GlyHis: 0.757 ± 0.174
3.282GlyIle: 3.282 ± 1.374
3.787GlyLys: 3.787 ± 0.874
4.039GlyLeu: 4.039 ± 0.39
1.01GlyMet: 1.01 ± 0.6
2.525GlyAsn: 2.525 ± 0.767
0.757GlyPro: 0.757 ± 0.746
2.272GlyGln: 2.272 ± 0.857
1.767GlyArg: 1.767 ± 0.68
3.787GlySer: 3.787 ± 0.712
2.525GlyThr: 2.525 ± 1.062
3.282GlyVal: 3.282 ± 0.305
1.01GlyTrp: 1.01 ± 0.286
2.272GlyTyr: 2.272 ± 0.327
0.0GlyXaa: 0.0 ± 0.0
His
0.757HisAla: 0.757 ± 0.45
0.505HisCys: 0.505 ± 0.153
0.757HisAsp: 0.757 ± 0.174
0.505HisGlu: 0.505 ± 0.498
1.262HisPhe: 1.262 ± 0.531
0.252HisGly: 0.252 ± 0.15
0.252HisHis: 0.252 ± 0.249
1.01HisIle: 1.01 ± 0.286
0.757HisLys: 0.757 ± 0.45
0.505HisLeu: 0.505 ± 0.3
0.0HisMet: 0.0 ± 0.0
0.505HisAsn: 0.505 ± 0.153
0.0HisPro: 0.0 ± 0.0
1.01HisGln: 1.01 ± 0.307
0.505HisArg: 0.505 ± 0.3
0.757HisSer: 0.757 ± 0.5
0.757HisThr: 0.757 ± 0.527
0.757HisVal: 0.757 ± 0.174
0.252HisTrp: 0.252 ± 0.249
1.01HisTyr: 1.01 ± 0.307
0.0HisXaa: 0.0 ± 0.0
Ile
3.534IleAla: 3.534 ± 0.604
1.515IleCys: 1.515 ± 0.771
6.059IleAsp: 6.059 ± 1.428
4.797IleGlu: 4.797 ± 1.019
2.02IlePhe: 2.02 ± 0.249
5.554IleGly: 5.554 ± 0.901
1.01IleHis: 1.01 ± 0.286
6.564IleIle: 6.564 ± 1.132
6.564IleLys: 6.564 ± 1.118
6.312IleLeu: 6.312 ± 1.214
3.03IleMet: 3.03 ± 0.059
6.059IleAsn: 6.059 ± 2.117
2.02IlePro: 2.02 ± 1.112
1.515IleGln: 1.515 ± 0.328
5.049IleArg: 5.049 ± 1.429
7.826IleSer: 7.826 ± 1.049
3.03IleThr: 3.03 ± 0.921
5.302IleVal: 5.302 ± 0.9
1.01IleTrp: 1.01 ± 0.307
3.787IleTyr: 3.787 ± 0.868
0.0IleXaa: 0.0 ± 0.0
Lys
3.282LysAla: 3.282 ± 0.734
0.0LysCys: 0.0 ± 0.0
6.312LysAsp: 6.312 ± 1.258
7.321LysGlu: 7.321 ± 1.654
2.525LysPhe: 2.525 ± 1.062
4.039LysGly: 4.039 ± 1.011
1.01LysHis: 1.01 ± 0.286
6.816LysIle: 6.816 ± 0.74
7.321LysLys: 7.321 ± 1.578
10.351LysLeu: 10.351 ± 1.592
2.525LysMet: 2.525 ± 0.443
7.321LysAsn: 7.321 ± 0.413
2.777LysPro: 2.777 ± 0.729
2.272LysGln: 2.272 ± 0.789
2.777LysArg: 2.777 ± 0.575
7.321LysSer: 7.321 ± 2.796
4.039LysThr: 4.039 ± 1.143
4.292LysVal: 4.292 ± 1.758
0.505LysTrp: 0.505 ± 0.608
3.787LysTyr: 3.787 ± 0.444
0.0LysXaa: 0.0 ± 0.0
Leu
3.787LeuAla: 3.787 ± 1.821
1.262LeuCys: 1.262 ± 0.877
6.816LeuAsp: 6.816 ± 0.858
6.312LeuGlu: 6.312 ± 0.362
3.787LeuPhe: 3.787 ± 0.421
3.03LeuGly: 3.03 ± 0.857
1.262LeuHis: 1.262 ± 0.291
7.826LeuIle: 7.826 ± 1.95
6.816LeuLys: 6.816 ± 1.108
6.312LeuLeu: 6.312 ± 0.805
3.03LeuMet: 3.03 ± 0.805
8.079LeuAsn: 8.079 ± 1.937
2.272LeuPro: 2.272 ± 0.579
3.282LeuGln: 3.282 ± 1.29
2.525LeuArg: 2.525 ± 0.096
7.321LeuSer: 7.321 ± 0.295
5.302LeuThr: 5.302 ± 1.318
3.787LeuVal: 3.787 ± 0.868
0.252LeuTrp: 0.252 ± 0.249
4.544LeuTyr: 4.544 ± 1.18
0.0LeuXaa: 0.0 ± 0.0
Met
1.767MetAla: 1.767 ± 0.432
0.757MetCys: 0.757 ± 0.45
1.262MetAsp: 1.262 ± 0.422
1.262MetGlu: 1.262 ± 0.383
1.767MetPhe: 1.767 ± 0.449
0.505MetGly: 0.505 ± 0.153
0.0MetHis: 0.0 ± 0.0
2.777MetIle: 2.777 ± 0.189
2.02MetLys: 2.02 ± 0.838
2.777MetLeu: 2.777 ± 1.328
0.252MetMet: 0.252 ± 0.15
2.777MetAsn: 2.777 ± 0.986
1.01MetPro: 1.01 ± 0.307
0.757MetGln: 0.757 ± 0.174
1.515MetArg: 1.515 ± 0.565
2.525MetSer: 2.525 ± 1.371
3.03MetThr: 3.03 ± 2.012
1.01MetVal: 1.01 ± 0.286
0.505MetTrp: 0.505 ± 0.498
0.505MetTyr: 0.505 ± 0.3
0.0MetXaa: 0.0 ± 0.0
Asn
2.02AsnAla: 2.02 ± 0.454
1.01AsnCys: 1.01 ± 0.63
5.049AsnAsp: 5.049 ± 0.193
3.282AsnGlu: 3.282 ± 0.857
3.03AsnPhe: 3.03 ± 0.656
3.534AsnGly: 3.534 ± 0.864
0.0AsnHis: 0.0 ± 0.0
9.089AsnIle: 9.089 ± 2.244
8.836AsnLys: 8.836 ± 1.373
11.108AsnLeu: 11.108 ± 1.95
2.777AsnMet: 2.777 ± 0.189
5.554AsnAsn: 5.554 ± 1.302
2.02AsnPro: 2.02 ± 0.614
1.767AsnGln: 1.767 ± 0.68
3.282AsnArg: 3.282 ± 1.276
3.282AsnSer: 3.282 ± 0.88
5.302AsnThr: 5.302 ± 0.633
3.03AsnVal: 3.03 ± 0.334
0.252AsnTrp: 0.252 ± 0.249
3.534AsnTyr: 3.534 ± 0.897
0.0AsnXaa: 0.0 ± 0.0
Pro
1.01ProAla: 1.01 ± 0.577
0.252ProCys: 0.252 ± 0.249
2.777ProAsp: 2.777 ± 0.575
1.767ProGlu: 1.767 ± 0.449
1.262ProPhe: 1.262 ± 0.291
1.515ProGly: 1.515 ± 0.565
0.252ProHis: 0.252 ± 0.15
2.525ProIle: 2.525 ± 1.091
2.02ProLys: 2.02 ± 0.454
1.515ProLeu: 1.515 ± 0.328
0.757ProMet: 0.757 ± 0.385
1.01ProAsn: 1.01 ± 0.307
0.757ProPro: 0.757 ± 0.5
0.0ProGln: 0.0 ± 0.0
1.01ProArg: 1.01 ± 0.63
1.515ProSer: 1.515 ± 0.46
1.767ProThr: 1.767 ± 1.151
1.767ProVal: 1.767 ± 1.073
0.252ProTrp: 0.252 ± 0.249
1.515ProTyr: 1.515 ± 0.347
0.0ProXaa: 0.0 ± 0.0
Gln
2.525GlnAla: 2.525 ± 1.155
0.757GlnCys: 0.757 ± 0.5
1.262GlnAsp: 1.262 ± 0.621
2.02GlnGlu: 2.02 ± 0.573
2.525GlnPhe: 2.525 ± 0.765
0.757GlnGly: 0.757 ± 0.174
0.0GlnHis: 0.0 ± 0.0
2.272GlnIle: 2.272 ± 0.828
2.525GlnLys: 2.525 ± 0.737
3.787GlnLeu: 3.787 ± 1.017
0.757GlnMet: 0.757 ± 0.174
3.03GlnAsn: 3.03 ± 0.628
0.252GlnPro: 0.252 ± 0.15
2.02GlnGln: 2.02 ± 0.908
0.757GlnArg: 0.757 ± 0.45
2.777GlnSer: 2.777 ± 0.569
2.02GlnThr: 2.02 ± 0.572
1.515GlnVal: 1.515 ± 1.673
0.252GlnTrp: 0.252 ± 0.249
0.505GlnTyr: 0.505 ± 0.3
0.0GlnXaa: 0.0 ± 0.0
Arg
2.02ArgAla: 2.02 ± 1.112
0.757ArgCys: 0.757 ± 0.5
1.767ArgAsp: 1.767 ± 0.821
1.767ArgGlu: 1.767 ± 0.711
2.777ArgPhe: 2.777 ± 0.729
2.525ArgGly: 2.525 ± 0.821
1.262ArgHis: 1.262 ± 0.291
3.03ArgIle: 3.03 ± 1.095
2.777ArgLys: 2.777 ± 0.668
2.272ArgLeu: 2.272 ± 1.007
0.0ArgMet: 0.0 ± 0.0
3.03ArgAsn: 3.03 ± 0.334
1.01ArgPro: 1.01 ± 0.286
2.02ArgGln: 2.02 ± 0.941
1.515ArgArg: 1.515 ± 0.712
2.777ArgSer: 2.777 ± 0.195
3.534ArgThr: 3.534 ± 0.864
2.525ArgVal: 2.525 ± 0.765
0.505ArgTrp: 0.505 ± 0.153
2.777ArgTyr: 2.777 ± 0.623
0.0ArgXaa: 0.0 ± 0.0
Ser
3.03SerAla: 3.03 ± 0.87
1.515SerCys: 1.515 ± 0.328
5.807SerAsp: 5.807 ± 2.574
5.049SerGlu: 5.049 ± 0.858
4.544SerPhe: 4.544 ± 1.159
5.554SerGly: 5.554 ± 0.757
0.505SerHis: 0.505 ± 0.498
5.554SerIle: 5.554 ± 0.891
4.797SerLys: 4.797 ± 1.073
4.797SerLeu: 4.797 ± 1.132
2.02SerMet: 2.02 ± 0.633
5.807SerAsn: 5.807 ± 0.146
1.767SerPro: 1.767 ± 0.432
3.03SerGln: 3.03 ± 0.721
2.272SerArg: 2.272 ± 0.692
4.544SerSer: 4.544 ± 0.829
6.059SerThr: 6.059 ± 2.558
3.787SerVal: 3.787 ± 0.486
0.252SerTrp: 0.252 ± 0.249
4.292SerTyr: 4.292 ± 0.761
0.0SerXaa: 0.0 ± 0.0
Thr
2.777ThrAla: 2.777 ± 0.569
1.01ThrCys: 1.01 ± 0.995
4.544ThrAsp: 4.544 ± 1.159
2.777ThrGlu: 2.777 ± 1.337
1.767ThrPhe: 1.767 ± 0.449
3.03ThrGly: 3.03 ± 0.811
0.252ThrHis: 0.252 ± 0.15
5.302ThrIle: 5.302 ± 0.166
5.807ThrLys: 5.807 ± 1.025
4.544ThrLeu: 4.544 ± 1.338
0.757ThrMet: 0.757 ± 0.5
5.049ThrAsn: 5.049 ± 0.807
1.515ThrPro: 1.515 ± 1.0
1.515ThrGln: 1.515 ± 0.565
2.272ThrArg: 2.272 ± 0.789
4.039ThrSer: 4.039 ± 0.29
3.787ThrThr: 3.787 ± 0.486
4.544ThrVal: 4.544 ± 0.519
0.252ThrTrp: 0.252 ± 0.15
3.534ThrTyr: 3.534 ± 0.499
0.0ThrXaa: 0.0 ± 0.0
Val
3.534ValAla: 3.534 ± 0.604
0.0ValCys: 0.0 ± 0.0
3.787ValAsp: 3.787 ± 1.148
3.282ValGlu: 3.282 ± 0.48
1.515ValPhe: 1.515 ± 0.46
4.292ValGly: 4.292 ± 1.299
1.262ValHis: 1.262 ± 0.75
3.03ValIle: 3.03 ± 1.258
6.564ValLys: 6.564 ± 3.07
4.544ValLeu: 4.544 ± 1.159
2.02ValMet: 2.02 ± 0.859
4.544ValAsn: 4.544 ± 1.042
1.767ValPro: 1.767 ± 0.783
1.767ValGln: 1.767 ± 0.472
2.02ValArg: 2.02 ± 0.573
3.787ValSer: 3.787 ± 1.061
3.282ValThr: 3.282 ± 1.374
3.534ValVal: 3.534 ± 0.499
0.505ValTrp: 0.505 ± 0.3
2.02ValTyr: 2.02 ± 0.838
0.0ValXaa: 0.0 ± 0.0
Trp
1.01TrpAla: 1.01 ± 1.079
0.0TrpCys: 0.0 ± 0.0
0.252TrpAsp: 0.252 ± 0.249
0.252TrpGlu: 0.252 ± 0.249
0.505TrpPhe: 0.505 ± 0.153
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.505TrpIle: 0.505 ± 0.498
0.757TrpLys: 0.757 ± 0.174
1.01TrpLeu: 1.01 ± 0.307
0.252TrpMet: 0.252 ± 0.249
0.505TrpAsn: 0.505 ± 0.498
0.505TrpPro: 0.505 ± 0.153
0.252TrpGln: 0.252 ± 0.249
0.0TrpArg: 0.0 ± 0.0
1.262TrpSer: 1.262 ± 0.291
0.0TrpThr: 0.0 ± 0.0
1.01TrpVal: 1.01 ± 0.286
0.252TrpTrp: 0.252 ± 0.249
0.505TrpTyr: 0.505 ± 0.498
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.02TyrAla: 2.02 ± 0.249
1.01TyrCys: 1.01 ± 0.6
2.02TyrAsp: 2.02 ± 0.454
3.534TyrGlu: 3.534 ± 0.794
2.777TyrPhe: 2.777 ± 0.983
1.01TyrGly: 1.01 ± 0.307
0.252TyrHis: 0.252 ± 0.249
4.039TyrIle: 4.039 ± 0.96
6.564TyrLys: 6.564 ± 1.98
4.039TyrLeu: 4.039 ± 0.797
0.505TyrMet: 0.505 ± 0.3
4.292TyrAsn: 4.292 ± 1.011
1.01TyrPro: 1.01 ± 0.307
1.767TyrGln: 1.767 ± 0.91
2.525TyrArg: 2.525 ± 0.096
3.787TyrSer: 3.787 ± 1.087
2.272TyrThr: 2.272 ± 0.831
1.767TyrVal: 1.767 ± 0.25
0.252TyrTrp: 0.252 ± 0.15
2.777TyrTyr: 2.777 ± 1.649
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3962 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski