Amino acid dipepetide frequency for Panax notoginseng virus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.063AlaAla: 5.063 ± 0.134
1.899AlaCys: 1.899 ± 1.207
3.165AlaAsp: 3.165 ± 1.341
2.532AlaGlu: 2.532 ± 0.067
0.633AlaPhe: 0.633 ± 0.402
5.063AlaGly: 5.063 ± 1.81
2.532AlaHis: 2.532 ± 0.771
1.266AlaIle: 1.266 ± 0.805
2.532AlaLys: 2.532 ± 0.771
6.329AlaLeu: 6.329 ± 1.843
5.063AlaMet: 5.063 ± 2.381
3.165AlaAsn: 3.165 ± 1.341
1.899AlaPro: 1.899 ± 1.307
2.532AlaGln: 2.532 ± 0.771
6.962AlaArg: 6.962 ± 1.912
2.532AlaSer: 2.532 ± 0.067
7.595AlaThr: 7.595 ± 0.201
3.165AlaVal: 3.165 ± 0.336
2.532AlaTrp: 2.532 ± 0.067
3.797AlaTyr: 3.797 ± 0.738
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.266CysAsp: 1.266 ± 0.033
2.532CysGlu: 2.532 ± 0.771
0.0CysPhe: 0.0 ± 0.0
1.899CysGly: 1.899 ± 0.469
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.633CysLeu: 0.633 ± 0.402
0.0CysMet: 0.0 ± 0.0
1.266CysAsn: 1.266 ± 0.805
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.532CysSer: 2.532 ± 0.771
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.633CysTrp: 0.633 ± 0.436
0.633CysTyr: 0.633 ± 0.402
0.0CysXaa: 0.0 ± 0.0
Asp
3.165AspAla: 3.165 ± 1.341
1.266AspCys: 1.266 ± 0.872
8.228AspAsp: 8.228 ± 3.151
2.532AspGlu: 2.532 ± 0.067
4.43AspPhe: 4.43 ± 0.536
6.329AspGly: 6.329 ± 0.167
0.633AspHis: 0.633 ± 0.436
3.165AspIle: 3.165 ± 1.174
1.899AspLys: 1.899 ± 0.469
5.063AspLeu: 5.063 ± 0.972
2.532AspMet: 2.532 ± 0.725
3.797AspAsn: 3.797 ± 0.938
0.633AspPro: 0.633 ± 0.436
2.532AspGln: 2.532 ± 0.905
3.797AspArg: 3.797 ± 1.777
3.165AspSer: 3.165 ± 0.336
1.899AspThr: 1.899 ± 1.307
6.962AspVal: 6.962 ± 0.235
2.532AspTrp: 2.532 ± 0.067
3.797AspTyr: 3.797 ± 0.738
0.0AspXaa: 0.0 ± 0.0
Glu
5.063GluAla: 5.063 ± 0.972
0.0GluCys: 0.0 ± 0.0
5.063GluAsp: 5.063 ± 0.972
7.595GluGlu: 7.595 ± 3.152
4.43GluPhe: 4.43 ± 0.302
3.797GluGly: 3.797 ± 0.1
1.266GluHis: 1.266 ± 0.805
4.43GluIle: 4.43 ± 0.536
3.797GluLys: 3.797 ± 0.738
3.797GluLeu: 3.797 ± 0.938
0.0GluMet: 0.0 ± 0.0
0.633GluAsn: 0.633 ± 0.436
1.266GluPro: 1.266 ± 0.805
0.0GluGln: 0.0 ± 0.0
1.899GluArg: 1.899 ± 0.469
3.797GluSer: 3.797 ± 0.938
1.899GluThr: 1.899 ± 0.369
5.696GluVal: 5.696 ± 0.269
3.165GluTrp: 3.165 ± 0.336
1.266GluTyr: 1.266 ± 0.033
0.0GluXaa: 0.0 ± 0.0
Phe
4.43PheAla: 4.43 ± 0.302
0.633PheCys: 0.633 ± 0.402
3.165PheAsp: 3.165 ± 0.336
1.266PheGlu: 1.266 ± 0.033
1.266PhePhe: 1.266 ± 0.872
1.899PheGly: 1.899 ± 1.207
0.633PheHis: 0.633 ± 0.436
1.266PheIle: 1.266 ± 0.872
1.899PheLys: 1.899 ± 1.207
2.532PheLeu: 2.532 ± 0.771
0.633PheMet: 0.633 ± 0.402
3.165PheAsn: 3.165 ± 1.341
2.532PhePro: 2.532 ± 0.067
0.633PheGln: 0.633 ± 0.436
6.329PheArg: 6.329 ± 0.671
1.899PheSer: 1.899 ± 0.469
1.899PheThr: 1.899 ± 1.307
5.063PheVal: 5.063 ± 1.81
1.266PheTrp: 1.266 ± 0.033
1.266PheTyr: 1.266 ± 0.033
0.0PheXaa: 0.0 ± 0.0
Gly
4.43GlyAla: 4.43 ± 1.14
0.633GlyCys: 0.633 ± 0.436
3.165GlyAsp: 3.165 ± 0.503
3.165GlyGlu: 3.165 ± 0.336
1.899GlyPhe: 1.899 ± 0.469
5.063GlyGly: 5.063 ± 1.81
3.165GlyHis: 3.165 ± 0.503
4.43GlyIle: 4.43 ± 1.14
4.43GlyLys: 4.43 ± 1.374
6.329GlyLeu: 6.329 ± 1.843
2.532GlyMet: 2.532 ± 0.067
1.266GlyAsn: 1.266 ± 0.805
1.266GlyPro: 1.266 ± 0.033
0.633GlyGln: 0.633 ± 0.436
1.899GlyArg: 1.899 ± 0.369
5.063GlySer: 5.063 ± 0.134
5.063GlyThr: 5.063 ± 0.972
5.696GlyVal: 5.696 ± 0.569
0.633GlyTrp: 0.633 ± 0.402
3.797GlyTyr: 3.797 ± 0.738
0.0GlyXaa: 0.0 ± 0.0
His
1.266HisAla: 1.266 ± 0.805
0.0HisCys: 0.0 ± 0.0
1.266HisAsp: 1.266 ± 0.805
1.899HisGlu: 1.899 ± 1.207
2.532HisPhe: 2.532 ± 0.905
1.266HisGly: 1.266 ± 0.805
0.633HisHis: 0.633 ± 0.402
2.532HisIle: 2.532 ± 0.067
1.266HisLys: 1.266 ± 0.805
0.0HisLeu: 0.0 ± 0.0
1.266HisMet: 1.266 ± 0.872
1.899HisAsn: 1.899 ± 1.207
0.633HisPro: 0.633 ± 0.436
0.0HisGln: 0.0 ± 0.0
3.165HisArg: 3.165 ± 1.174
3.797HisSer: 3.797 ± 1.576
3.165HisThr: 3.165 ± 0.503
1.266HisVal: 1.266 ± 0.872
1.266HisTrp: 1.266 ± 0.872
0.633HisTyr: 0.633 ± 0.436
0.0HisXaa: 0.0 ± 0.0
Ile
2.532IleAla: 2.532 ± 0.905
0.0IleCys: 0.0 ± 0.0
4.43IleAsp: 4.43 ± 2.212
2.532IleGlu: 2.532 ± 0.067
1.266IlePhe: 1.266 ± 0.805
2.532IleGly: 2.532 ± 0.067
1.899IleHis: 1.899 ± 0.369
1.266IleIle: 1.266 ± 0.805
3.165IleLys: 3.165 ± 2.012
5.063IleLeu: 5.063 ± 0.704
0.0IleMet: 0.0 ± 0.0
1.899IleAsn: 1.899 ± 0.369
3.797IlePro: 3.797 ± 0.738
0.0IleGln: 0.0 ± 0.0
5.696IleArg: 5.696 ± 1.107
5.696IleSer: 5.696 ± 1.408
5.063IleThr: 5.063 ± 1.543
1.266IleVal: 1.266 ± 0.805
0.633IleTrp: 0.633 ± 0.402
1.899IleTyr: 1.899 ± 1.207
0.0IleXaa: 0.0 ± 0.0
Lys
1.266LysAla: 1.266 ± 0.805
1.266LysCys: 1.266 ± 0.805
3.165LysAsp: 3.165 ± 0.503
1.899LysGlu: 1.899 ± 0.369
1.266LysPhe: 1.266 ± 0.805
4.43LysGly: 4.43 ± 0.536
0.633LysHis: 0.633 ± 0.402
3.797LysIle: 3.797 ± 0.738
6.962LysLys: 6.962 ± 1.073
4.43LysLeu: 4.43 ± 0.536
2.532LysMet: 2.532 ± 0.067
0.633LysAsn: 0.633 ± 0.436
0.633LysPro: 0.633 ± 0.402
1.266LysGln: 1.266 ± 0.033
1.899LysArg: 1.899 ± 0.469
2.532LysSer: 2.532 ± 1.609
3.165LysThr: 3.165 ± 1.174
6.962LysVal: 6.962 ± 1.073
0.0LysTrp: 0.0 ± 0.0
4.43LysTyr: 4.43 ± 2.816
0.0LysXaa: 0.0 ± 0.0
Leu
2.532LeuAla: 2.532 ± 0.067
2.532LeuCys: 2.532 ± 0.067
4.43LeuAsp: 4.43 ± 1.374
3.165LeuGlu: 3.165 ± 1.341
4.43LeuPhe: 4.43 ± 1.978
4.43LeuGly: 4.43 ± 0.536
1.899LeuHis: 1.899 ± 1.307
2.532LeuIle: 2.532 ± 1.609
7.595LeuLys: 7.595 ± 0.201
6.962LeuLeu: 6.962 ± 0.603
1.899LeuMet: 1.899 ± 1.132
3.165LeuAsn: 3.165 ± 0.336
2.532LeuPro: 2.532 ± 0.905
1.899LeuGln: 1.899 ± 0.369
5.696LeuArg: 5.696 ± 0.569
8.861LeuSer: 8.861 ± 0.234
8.228LeuThr: 8.228 ± 1.474
4.43LeuVal: 4.43 ± 0.302
0.0LeuTrp: 0.0 ± 0.0
4.43LeuTyr: 4.43 ± 1.374
0.0LeuXaa: 0.0 ± 0.0
Met
1.899MetAla: 1.899 ± 0.469
0.0MetCys: 0.0 ± 0.0
3.165MetAsp: 3.165 ± 0.503
2.532MetGlu: 2.532 ± 0.771
1.899MetPhe: 1.899 ± 0.369
1.266MetGly: 1.266 ± 0.033
0.633MetHis: 0.633 ± 0.402
2.532MetIle: 2.532 ± 0.067
1.266MetLys: 1.266 ± 0.033
3.797MetLeu: 3.797 ± 0.1
1.899MetMet: 1.899 ± 0.369
1.266MetAsn: 1.266 ± 0.805
1.266MetPro: 1.266 ± 0.033
0.633MetGln: 0.633 ± 0.436
0.633MetArg: 0.633 ± 0.436
3.165MetSer: 3.165 ± 0.336
0.633MetThr: 0.633 ± 0.436
1.899MetVal: 1.899 ± 0.469
0.0MetTrp: 0.0 ± 0.0
3.165MetTyr: 3.165 ± 0.503
0.0MetXaa: 0.0 ± 0.0
Asn
3.165AsnAla: 3.165 ± 0.503
0.0AsnCys: 0.0 ± 0.0
3.165AsnAsp: 3.165 ± 1.341
2.532AsnGlu: 2.532 ± 0.905
1.899AsnPhe: 1.899 ± 0.469
1.899AsnGly: 1.899 ± 0.369
1.266AsnHis: 1.266 ± 0.033
3.165AsnIle: 3.165 ± 0.336
0.633AsnLys: 0.633 ± 0.402
3.165AsnLeu: 3.165 ± 0.336
3.165AsnMet: 3.165 ± 0.503
3.797AsnAsn: 3.797 ± 2.414
0.0AsnPro: 0.0 ± 0.0
0.633AsnGln: 0.633 ± 0.402
4.43AsnArg: 4.43 ± 0.536
1.266AsnSer: 1.266 ± 0.033
1.266AsnThr: 1.266 ± 0.033
1.899AsnVal: 1.899 ± 0.369
0.633AsnTrp: 0.633 ± 0.436
1.266AsnTyr: 1.266 ± 0.033
0.0AsnXaa: 0.0 ± 0.0
Pro
1.899ProAla: 1.899 ± 0.469
0.0ProCys: 0.0 ± 0.0
1.899ProAsp: 1.899 ± 1.307
4.43ProGlu: 4.43 ± 1.374
1.266ProPhe: 1.266 ± 0.872
2.532ProGly: 2.532 ± 0.905
0.0ProHis: 0.0 ± 0.0
1.266ProIle: 1.266 ± 0.805
0.0ProLys: 0.0 ± 0.0
3.165ProLeu: 3.165 ± 0.503
1.899ProMet: 1.899 ± 0.469
1.899ProAsn: 1.899 ± 0.469
2.532ProPro: 2.532 ± 0.067
0.633ProGln: 0.633 ± 0.402
2.532ProArg: 2.532 ± 0.067
1.266ProSer: 1.266 ± 0.033
1.899ProThr: 1.899 ± 0.469
2.532ProVal: 2.532 ± 0.905
0.633ProTrp: 0.633 ± 0.436
1.899ProTyr: 1.899 ± 0.369
0.0ProXaa: 0.0 ± 0.0
Gln
3.165GlnAla: 3.165 ± 0.336
0.633GlnCys: 0.633 ± 0.402
0.633GlnAsp: 0.633 ± 0.436
0.633GlnGlu: 0.633 ± 0.402
2.532GlnPhe: 2.532 ± 1.743
0.633GlnGly: 0.633 ± 0.436
1.266GlnHis: 1.266 ± 0.805
0.633GlnIle: 0.633 ± 0.436
0.0GlnLys: 0.0 ± 0.0
1.899GlnLeu: 1.899 ± 1.207
0.0GlnMet: 0.0 ± 0.0
1.899GlnAsn: 1.899 ± 0.469
0.633GlnPro: 0.633 ± 0.436
0.0GlnGln: 0.0 ± 0.0
0.633GlnArg: 0.633 ± 0.402
0.0GlnSer: 0.0 ± 0.0
1.266GlnThr: 1.266 ± 0.033
2.532GlnVal: 2.532 ± 0.067
0.0GlnTrp: 0.0 ± 0.0
1.899GlnTyr: 1.899 ± 1.207
0.0GlnXaa: 0.0 ± 0.0
Arg
8.228ArgAla: 8.228 ± 2.716
1.899ArgCys: 1.899 ± 0.369
4.43ArgAsp: 4.43 ± 1.14
7.595ArgGlu: 7.595 ± 0.201
3.165ArgPhe: 3.165 ± 0.503
5.063ArgGly: 5.063 ± 0.972
1.899ArgHis: 1.899 ± 0.369
2.532ArgIle: 2.532 ± 0.771
3.797ArgLys: 3.797 ± 0.1
8.861ArgLeu: 8.861 ± 1.91
2.532ArgMet: 2.532 ± 0.771
1.899ArgAsn: 1.899 ± 0.469
1.899ArgPro: 1.899 ± 1.207
1.266ArgGln: 1.266 ± 0.033
3.797ArgArg: 3.797 ± 0.738
3.797ArgSer: 3.797 ± 0.1
3.165ArgThr: 3.165 ± 0.503
3.797ArgVal: 3.797 ± 0.738
0.633ArgTrp: 0.633 ± 0.402
1.899ArgTyr: 1.899 ± 0.469
0.0ArgXaa: 0.0 ± 0.0
Ser
6.962SerAla: 6.962 ± 1.441
0.0SerCys: 0.0 ± 0.0
2.532SerAsp: 2.532 ± 0.067
1.899SerGlu: 1.899 ± 1.307
3.165SerPhe: 3.165 ± 0.503
1.899SerGly: 1.899 ± 0.369
2.532SerHis: 2.532 ± 0.067
4.43SerIle: 4.43 ± 1.14
1.899SerLys: 1.899 ± 0.369
3.165SerLeu: 3.165 ± 2.179
2.532SerMet: 2.532 ± 0.771
0.633SerAsn: 0.633 ± 0.402
1.899SerPro: 1.899 ± 1.307
2.532SerGln: 2.532 ± 0.771
6.329SerArg: 6.329 ± 0.671
4.43SerSer: 4.43 ± 0.302
4.43SerThr: 4.43 ± 0.536
10.127SerVal: 10.127 ± 4.761
1.266SerTrp: 1.266 ± 0.872
1.266SerTyr: 1.266 ± 0.872
0.0SerXaa: 0.0 ± 0.0
Thr
5.696ThrAla: 5.696 ± 0.569
0.0ThrCys: 0.0 ± 0.0
3.797ThrAsp: 3.797 ± 0.938
1.266ThrGlu: 1.266 ± 0.033
2.532ThrPhe: 2.532 ± 0.067
5.696ThrGly: 5.696 ± 0.569
3.797ThrHis: 3.797 ± 1.576
3.797ThrIle: 3.797 ± 0.938
2.532ThrLys: 2.532 ± 0.771
8.228ThrLeu: 8.228 ± 0.202
1.899ThrMet: 1.899 ± 0.469
1.899ThrAsn: 1.899 ± 0.469
4.43ThrPro: 4.43 ± 2.212
1.266ThrGln: 1.266 ± 0.033
6.962ThrArg: 6.962 ± 1.073
3.165ThrSer: 3.165 ± 1.341
2.532ThrThr: 2.532 ± 0.067
5.063ThrVal: 5.063 ± 0.134
0.0ThrTrp: 0.0 ± 0.0
2.532ThrTyr: 2.532 ± 0.905
0.0ThrXaa: 0.0 ± 0.0
Val
3.797ValAla: 3.797 ± 0.738
0.0ValCys: 0.0 ± 0.0
6.962ValAsp: 6.962 ± 1.073
3.165ValGlu: 3.165 ± 0.503
3.797ValPhe: 3.797 ± 0.1
5.696ValGly: 5.696 ± 1.107
3.165ValHis: 3.165 ± 1.174
2.532ValIle: 2.532 ± 0.067
4.43ValLys: 4.43 ± 1.978
5.063ValLeu: 5.063 ± 0.704
1.266ValMet: 1.266 ± 0.872
2.532ValAsn: 2.532 ± 0.067
3.797ValPro: 3.797 ± 0.938
3.165ValGln: 3.165 ± 0.336
6.329ValArg: 6.329 ± 0.167
3.797ValSer: 3.797 ± 0.1
10.759ValThr: 10.759 ± 0.973
2.532ValVal: 2.532 ± 0.771
1.266ValTrp: 1.266 ± 0.033
2.532ValTyr: 2.532 ± 0.067
0.0ValXaa: 0.0 ± 0.0
Trp
2.532TrpAla: 2.532 ± 0.067
0.633TrpCys: 0.633 ± 0.402
0.0TrpAsp: 0.0 ± 0.0
1.899TrpGlu: 1.899 ± 0.369
0.0TrpPhe: 0.0 ± 0.0
1.266TrpGly: 1.266 ± 0.872
0.0TrpHis: 0.0 ± 0.0
0.633TrpIle: 0.633 ± 0.436
1.266TrpLys: 1.266 ± 0.872
1.266TrpLeu: 1.266 ± 0.033
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.266TrpPro: 1.266 ± 0.872
0.633TrpGln: 0.633 ± 0.402
1.899TrpArg: 1.899 ± 0.369
1.266TrpSer: 1.266 ± 0.033
0.633TrpThr: 0.633 ± 0.436
1.266TrpVal: 1.266 ± 0.805
0.0TrpTrp: 0.0 ± 0.0
0.633TrpTyr: 0.633 ± 0.436
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.165TyrAla: 3.165 ± 2.012
0.0TyrCys: 0.0 ± 0.0
4.43TyrAsp: 4.43 ± 0.536
3.797TyrGlu: 3.797 ± 0.1
1.266TyrPhe: 1.266 ± 0.033
1.899TyrGly: 1.899 ± 1.207
1.899TyrHis: 1.899 ± 0.469
4.43TyrIle: 4.43 ± 0.302
3.797TyrLys: 3.797 ± 2.414
2.532TyrLeu: 2.532 ± 0.771
1.266TyrMet: 1.266 ± 0.033
2.532TyrAsn: 2.532 ± 0.905
1.266TyrPro: 1.266 ± 0.872
0.633TyrGln: 0.633 ± 0.436
1.266TyrArg: 1.266 ± 0.033
1.899TyrSer: 1.899 ± 0.369
2.532TyrThr: 2.532 ± 0.905
4.43TyrVal: 4.43 ± 0.302
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1581 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski