Angiostrongylus costaricensis (Nematode worm)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Strongylida; Metastrongyloidea; Angiostrongylidae; Angiostrongylus

Average proteome isoelectric point is 6.88

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 13350 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0R3PIY9|A0A0R3PIY9_ANGCS HTH_48 domain-containing protein OS=Angiostrongylus costaricensis OX=334426 GN=ACOC_LOCUS4367 PE=4 SV=1
MM1 pKa = 6.74VTDD4 pKa = 4.2GNGTLGHH11 pKa = 5.92YY12 pKa = 7.41SQWTTTACAMMDD24 pKa = 3.71DD25 pKa = 3.95RR26 pKa = 11.84AMLGSLSIDD35 pKa = 3.74DD36 pKa = 4.16DD37 pKa = 4.04CLYY40 pKa = 11.26GDD42 pKa = 3.85EE43 pKa = 4.81RR44 pKa = 11.84SGNVLASFSRR54 pKa = 11.84DD55 pKa = 3.67DD56 pKa = 3.86DD57 pKa = 3.95CLRR60 pKa = 11.84CDD62 pKa = 4.15GQPQNALGMDD72 pKa = 3.81TLLEE76 pKa = 4.25VV77 pKa = 3.84

Molecular weight: 8.34 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0R3PJI1|A0A0R3PJI1_ANGCS Uncharacterized protein OS=Angiostrongylus costaricensis OX=334426 GN=ACOC_LOCUS4612 PE=3 SV=1
MM1 pKa = 7.43TSLPPRR7 pKa = 11.84RR8 pKa = 11.84LQKK11 pKa = 9.7VAGRR15 pKa = 11.84GRR17 pKa = 11.84RR18 pKa = 11.84RR19 pKa = 11.84LRR21 pKa = 11.84VLRR24 pKa = 11.84SRR26 pKa = 11.84RR27 pKa = 11.84RR28 pKa = 11.84RR29 pKa = 11.84CGLQWCAVAGRR40 pKa = 11.84RR41 pKa = 11.84AVGGAAAAHH50 pKa = 6.27RR51 pKa = 11.84LPRR54 pKa = 11.84SVAAALSRR62 pKa = 11.84DD63 pKa = 3.53RR64 pKa = 11.84SSVTMRR70 pKa = 11.84RR71 pKa = 11.84QRR73 pKa = 11.84GVLPLL78 pKa = 3.84

Molecular weight: 8.72 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

13350

0

13350

4341050

29

6688

325.2

36.71

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.572 ± 0.02

2.288 ± 0.02

5.363 ± 0.017

6.38 ± 0.026

4.563 ± 0.017

5.666 ± 0.024

2.495 ± 0.01

5.731 ± 0.016

5.516 ± 0.022

9.403 ± 0.026

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.585 ± 0.01

4.243 ± 0.013

4.688 ± 0.024

3.758 ± 0.019

6.193 ± 0.018

7.849 ± 0.022

5.447 ± 0.016

6.926 ± 0.019

1.186 ± 0.008

3.148 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski