Amino acid dipepetide frequency for Malvastrum yellow vein Baoshan virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.695AlaAla: 2.695 ± 1.333
1.797AlaCys: 1.797 ± 0.706
0.898AlaAsp: 0.898 ± 0.797
0.898AlaGlu: 0.898 ± 1.031
0.0AlaPhe: 0.0 ± 0.0
0.898AlaGly: 0.898 ± 0.797
0.898AlaHis: 0.898 ± 0.894
1.797AlaIle: 1.797 ± 0.889
4.492AlaLys: 4.492 ± 0.984
6.289AlaLeu: 6.289 ± 1.969
0.0AlaMet: 0.0 ± 0.0
2.695AlaAsn: 2.695 ± 1.118
1.797AlaPro: 1.797 ± 1.092
5.391AlaGln: 5.391 ± 1.697
2.695AlaArg: 2.695 ± 2.0
3.594AlaSer: 3.594 ± 2.153
2.695AlaThr: 2.695 ± 2.391
0.898AlaVal: 0.898 ± 0.797
1.797AlaTrp: 1.797 ± 0.889
1.797AlaTyr: 1.797 ± 0.889
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.797CysCys: 1.797 ± 1.789
0.0CysAsp: 0.0 ± 0.0
1.797CysGlu: 1.797 ± 0.706
1.797CysPhe: 1.797 ± 1.204
1.797CysGly: 1.797 ± 0.886
0.0CysHis: 0.0 ± 0.0
0.898CysIle: 0.898 ± 0.797
0.898CysLys: 0.898 ± 0.797
0.0CysLeu: 0.0 ± 0.0
0.898CysMet: 0.898 ± 0.894
1.797CysAsn: 1.797 ± 0.886
1.797CysPro: 1.797 ± 1.789
0.898CysGln: 0.898 ± 0.667
1.797CysArg: 1.797 ± 0.979
3.594CysSer: 3.594 ± 1.765
1.797CysThr: 1.797 ± 1.122
0.898CysVal: 0.898 ± 0.797
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.695AspAla: 2.695 ± 2.0
0.0AspCys: 0.0 ± 0.0
2.695AspAsp: 2.695 ± 1.176
3.594AspGlu: 3.594 ± 1.006
1.797AspPhe: 1.797 ± 0.706
2.695AspGly: 2.695 ± 2.0
0.898AspHis: 0.898 ± 0.878
1.797AspIle: 1.797 ± 1.054
0.898AspLys: 0.898 ± 0.667
7.188AspLeu: 7.188 ± 2.43
0.898AspMet: 0.898 ± 0.832
0.898AspAsn: 0.898 ± 0.797
3.594AspPro: 3.594 ± 1.676
0.898AspGln: 0.898 ± 0.667
2.695AspArg: 2.695 ± 1.35
2.695AspSer: 2.695 ± 0.958
2.695AspThr: 2.695 ± 0.858
6.289AspVal: 6.289 ± 2.532
1.797AspTrp: 1.797 ± 0.886
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.594GluAla: 3.594 ± 0.864
0.898GluCys: 0.898 ± 0.878
0.898GluAsp: 0.898 ± 0.667
5.391GluGlu: 5.391 ± 4.0
3.594GluPhe: 3.594 ± 1.986
6.289GluGly: 6.289 ± 1.996
0.898GluHis: 0.898 ± 0.878
0.898GluIle: 0.898 ± 0.832
0.898GluLys: 0.898 ± 0.667
5.391GluLeu: 5.391 ± 2.444
0.0GluMet: 0.0 ± 0.0
4.492GluAsn: 4.492 ± 2.029
2.695GluPro: 2.695 ± 0.793
2.695GluGln: 2.695 ± 1.28
0.0GluArg: 0.0 ± 0.0
4.492GluSer: 4.492 ± 1.095
2.695GluThr: 2.695 ± 1.416
2.695GluVal: 2.695 ± 1.228
2.695GluTrp: 2.695 ± 1.299
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.898PheCys: 0.898 ± 0.797
3.594PheAsp: 3.594 ± 1.411
1.797PheGlu: 1.797 ± 0.706
1.797PhePhe: 1.797 ± 0.706
0.898PheGly: 0.898 ± 0.797
1.797PheHis: 1.797 ± 1.333
0.0PheIle: 0.0 ± 0.0
3.594PheLys: 3.594 ± 1.778
8.985PheLeu: 8.985 ± 2.479
0.898PheMet: 0.898 ± 0.667
3.594PheAsn: 3.594 ± 1.968
0.898PhePro: 0.898 ± 0.894
1.797PheGln: 1.797 ± 0.886
2.695PheArg: 2.695 ± 2.328
1.797PheSer: 1.797 ± 0.886
3.594PheThr: 3.594 ± 1.298
2.695PheVal: 2.695 ± 1.118
0.0PheTrp: 0.0 ± 0.0
1.797PheTyr: 1.797 ± 1.077
0.0PheXaa: 0.0 ± 0.0
Gly
4.492GlyAla: 4.492 ± 0.995
2.695GlyCys: 2.695 ± 1.851
2.695GlyAsp: 2.695 ± 1.118
4.492GlyGlu: 4.492 ± 1.612
1.797GlyPhe: 1.797 ± 1.177
2.695GlyGly: 2.695 ± 1.118
1.797GlyHis: 1.797 ± 0.886
0.898GlyIle: 0.898 ± 0.667
6.289GlyLys: 6.289 ± 2.68
1.797GlyLeu: 1.797 ± 1.054
0.0GlyMet: 0.0 ± 0.0
0.898GlyAsn: 0.898 ± 1.031
3.594GlyPro: 3.594 ± 1.7
2.695GlyGln: 2.695 ± 0.958
0.898GlyArg: 0.898 ± 0.667
5.391GlySer: 5.391 ± 2.078
3.594GlyThr: 3.594 ± 1.809
2.695GlyVal: 2.695 ± 1.941
0.0GlyTrp: 0.0 ± 0.0
1.797GlyTyr: 1.797 ± 1.789
0.0GlyXaa: 0.0 ± 0.0
His
0.898HisAla: 0.898 ± 0.797
3.594HisCys: 3.594 ± 1.676
1.797HisAsp: 1.797 ± 1.122
2.695HisGlu: 2.695 ± 1.144
3.594HisPhe: 3.594 ± 1.986
2.695HisGly: 2.695 ± 1.874
0.898HisHis: 0.898 ± 0.878
1.797HisIle: 1.797 ± 0.706
2.695HisLys: 2.695 ± 1.438
1.797HisLeu: 1.797 ± 1.092
0.0HisMet: 0.0 ± 0.0
2.695HisAsn: 2.695 ± 1.299
2.695HisPro: 2.695 ± 1.144
0.0HisGln: 0.0 ± 0.0
3.594HisArg: 3.594 ± 2.245
1.797HisSer: 1.797 ± 1.17
0.898HisThr: 0.898 ± 0.797
1.797HisVal: 1.797 ± 0.889
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.898IleCys: 0.898 ± 0.667
2.695IleAsp: 2.695 ± 2.0
1.797IleGlu: 1.797 ± 0.889
3.594IlePhe: 3.594 ± 2.03
0.898IleGly: 0.898 ± 0.797
1.797IleHis: 1.797 ± 0.886
1.797IleIle: 1.797 ± 1.663
5.391IleLys: 5.391 ± 0.746
1.797IleLeu: 1.797 ± 1.223
0.0IleMet: 0.0 ± 0.0
2.695IleAsn: 2.695 ± 1.057
0.898IlePro: 0.898 ± 0.667
4.492IleGln: 4.492 ± 1.763
5.391IleArg: 5.391 ± 1.711
7.188IleSer: 7.188 ± 1.623
2.695IleThr: 2.695 ± 1.941
1.797IleVal: 1.797 ± 0.706
3.594IleTrp: 3.594 ± 2.493
1.797IleTyr: 1.797 ± 1.054
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
1.797LysCys: 1.797 ± 0.889
2.695LysAsp: 2.695 ± 1.299
3.594LysGlu: 3.594 ± 1.7
2.695LysPhe: 2.695 ± 1.118
1.797LysGly: 1.797 ± 1.092
0.898LysHis: 0.898 ± 0.667
6.289LysIle: 6.289 ± 1.793
4.492LysLys: 4.492 ± 0.886
0.898LysLeu: 0.898 ± 0.832
0.0LysMet: 0.0 ± 0.0
5.391LysAsn: 5.391 ± 2.236
3.594LysPro: 3.594 ± 0.864
0.0LysGln: 0.0 ± 0.0
2.695LysArg: 2.695 ± 1.738
8.086LysSer: 8.086 ± 2.495
1.797LysThr: 1.797 ± 0.889
5.391LysVal: 5.391 ± 2.835
0.898LysTrp: 0.898 ± 0.797
4.492LysTyr: 4.492 ± 0.995
0.0LysXaa: 0.0 ± 0.0
Leu
0.898LeuAla: 0.898 ± 0.667
1.797LeuCys: 1.797 ± 1.333
3.594LeuAsp: 3.594 ± 1.865
4.492LeuGlu: 4.492 ± 2.482
1.797LeuPhe: 1.797 ± 1.204
4.492LeuGly: 4.492 ± 1.52
1.797LeuHis: 1.797 ± 0.889
4.492LeuIle: 4.492 ± 2.153
5.391LeuLys: 5.391 ± 1.284
2.695LeuLeu: 2.695 ± 2.152
1.797LeuMet: 1.797 ± 1.17
8.985LeuAsn: 8.985 ± 2.269
0.898LeuPro: 0.898 ± 0.878
4.492LeuGln: 4.492 ± 1.483
6.289LeuArg: 6.289 ± 2.672
4.492LeuSer: 4.492 ± 1.837
6.289LeuThr: 6.289 ± 2.202
2.695LeuVal: 2.695 ± 1.35
0.0LeuTrp: 0.0 ± 0.0
3.594LeuTyr: 3.594 ± 0.899
0.0LeuXaa: 0.0 ± 0.0
Met
0.898MetAla: 0.898 ± 0.797
0.898MetCys: 0.898 ± 0.797
2.695MetAsp: 2.695 ± 1.724
0.898MetGlu: 0.898 ± 0.878
1.797MetPhe: 1.797 ± 1.594
1.797MetGly: 1.797 ± 1.092
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.797MetLeu: 1.797 ± 1.077
0.0MetMet: 0.0 ± 0.872
0.898MetAsn: 0.898 ± 0.832
0.898MetPro: 0.898 ± 0.667
0.0MetGln: 0.0 ± 0.0
0.898MetArg: 0.898 ± 0.878
0.898MetSer: 0.898 ± 0.797
0.898MetThr: 0.898 ± 0.832
0.0MetVal: 0.0 ± 0.0
2.695MetTrp: 2.695 ± 0.858
2.695MetTyr: 2.695 ± 1.674
0.0MetXaa: 0.0 ± 0.0
Asn
4.492AsnAla: 4.492 ± 1.526
0.898AsnCys: 0.898 ± 0.878
1.797AsnAsp: 1.797 ± 1.333
1.797AsnGlu: 1.797 ± 1.077
1.797AsnPhe: 1.797 ± 1.122
0.898AsnGly: 0.898 ± 1.031
4.492AsnHis: 4.492 ± 2.213
2.695AsnIle: 2.695 ± 0.793
0.898AsnLys: 0.898 ± 0.667
6.289AsnLeu: 6.289 ± 2.013
3.594AsnMet: 3.594 ± 1.687
5.391AsnAsn: 5.391 ± 1.803
5.391AsnPro: 5.391 ± 1.135
3.594AsnGln: 3.594 ± 0.981
4.492AsnArg: 4.492 ± 1.331
1.797AsnSer: 1.797 ± 1.333
2.695AsnThr: 2.695 ± 2.0
6.289AsnVal: 6.289 ± 1.853
0.898AsnTrp: 0.898 ± 0.667
4.492AsnTyr: 4.492 ± 0.995
0.0AsnXaa: 0.0 ± 0.0
Pro
2.695ProAla: 2.695 ± 1.716
1.797ProCys: 1.797 ± 1.077
2.695ProAsp: 2.695 ± 0.858
0.898ProGlu: 0.898 ± 0.894
1.797ProPhe: 1.797 ± 0.889
1.797ProGly: 1.797 ± 1.092
4.492ProHis: 4.492 ± 2.602
2.695ProIle: 2.695 ± 1.935
2.695ProLys: 2.695 ± 2.0
5.391ProLeu: 5.391 ± 1.697
0.898ProMet: 0.898 ± 0.867
3.594ProAsn: 3.594 ± 1.294
1.797ProPro: 1.797 ± 0.889
5.391ProGln: 5.391 ± 1.457
5.391ProArg: 5.391 ± 2.317
5.391ProSer: 5.391 ± 4.378
8.985ProThr: 8.985 ± 2.677
2.695ProVal: 2.695 ± 0.858
0.0ProTrp: 0.0 ± 0.0
0.898ProTyr: 0.898 ± 0.797
0.0ProXaa: 0.0 ± 0.0
Gln
4.492GlnAla: 4.492 ± 1.647
0.0GlnCys: 0.0 ± 0.0
3.594GlnAsp: 3.594 ± 1.892
2.695GlnGlu: 2.695 ± 0.958
2.695GlnPhe: 2.695 ± 1.333
1.797GlnGly: 1.797 ± 1.333
0.898GlnHis: 0.898 ± 0.878
1.797GlnIle: 1.797 ± 1.333
0.898GlnLys: 0.898 ± 0.894
2.695GlnLeu: 2.695 ± 1.055
0.0GlnMet: 0.0 ± 0.0
3.594GlnAsn: 3.594 ± 1.316
4.492GlnPro: 4.492 ± 2.385
2.695GlnGln: 2.695 ± 1.118
0.898GlnArg: 0.898 ± 0.667
4.492GlnSer: 4.492 ± 2.328
0.898GlnThr: 0.898 ± 0.832
5.391GlnVal: 5.391 ± 2.407
0.0GlnTrp: 0.0 ± 0.0
1.797GlnTyr: 1.797 ± 1.17
0.0GlnXaa: 0.0 ± 0.0
Arg
0.898ArgAla: 0.898 ± 0.832
0.898ArgCys: 0.898 ± 0.894
2.695ArgAsp: 2.695 ± 1.35
4.492ArgGlu: 4.492 ± 1.483
1.797ArgPhe: 1.797 ± 0.706
3.594ArgGly: 3.594 ± 1.367
4.492ArgHis: 4.492 ± 2.88
3.594ArgIle: 3.594 ± 1.464
2.695ArgLys: 2.695 ± 1.738
2.695ArgLeu: 2.695 ± 1.358
2.695ArgMet: 2.695 ± 2.391
1.797ArgAsn: 1.797 ± 1.177
5.391ArgPro: 5.391 ± 1.832
0.0ArgGln: 0.0 ± 0.0
7.188ArgArg: 7.188 ± 3.307
8.086ArgSer: 8.086 ± 1.443
3.594ArgThr: 3.594 ± 2.085
5.391ArgVal: 5.391 ± 2.424
0.0ArgTrp: 0.0 ± 0.0
1.797ArgTyr: 1.797 ± 1.077
0.0ArgXaa: 0.0 ± 0.0
Ser
3.594SerAla: 3.594 ± 1.404
0.898SerCys: 0.898 ± 0.894
3.594SerAsp: 3.594 ± 1.558
6.289SerGlu: 6.289 ± 1.388
3.594SerPhe: 3.594 ± 0.981
4.492SerGly: 4.492 ± 1.763
0.898SerHis: 0.898 ± 0.878
8.086SerIle: 8.086 ± 2.714
7.188SerLys: 7.188 ± 1.906
0.898SerLeu: 0.898 ± 0.667
1.797SerMet: 1.797 ± 0.926
5.391SerAsn: 5.391 ± 1.591
8.985SerPro: 8.985 ± 2.409
1.797SerGln: 1.797 ± 0.979
5.391SerArg: 5.391 ± 1.276
18.868SerSer: 18.868 ± 7.809
6.289SerThr: 6.289 ± 3.173
3.594SerVal: 3.594 ± 1.318
0.0SerTrp: 0.0 ± 0.0
2.695SerTyr: 2.695 ± 1.299
0.0SerXaa: 0.0 ± 0.0
Thr
4.492ThrAla: 4.492 ± 1.053
0.898ThrCys: 0.898 ± 1.031
1.797ThrAsp: 1.797 ± 2.061
0.0ThrGlu: 0.0 ± 0.0
0.898ThrPhe: 0.898 ± 1.031
6.289ThrGly: 6.289 ± 2.213
4.492ThrHis: 4.492 ± 2.268
1.797ThrIle: 1.797 ± 0.889
1.797ThrLys: 1.797 ± 0.706
5.391ThrLeu: 5.391 ± 1.445
2.695ThrMet: 2.695 ± 1.587
4.492ThrAsn: 4.492 ± 2.029
6.289ThrPro: 6.289 ± 1.665
2.695ThrGln: 2.695 ± 1.057
3.594ThrArg: 3.594 ± 1.382
2.695ThrSer: 2.695 ± 2.209
1.797ThrThr: 1.797 ± 1.312
4.492ThrVal: 4.492 ± 2.695
0.898ThrTrp: 0.898 ± 1.031
1.797ThrTyr: 1.797 ± 0.889
0.0ThrXaa: 0.0 ± 0.0
Val
0.898ValAla: 0.898 ± 0.797
0.0ValCys: 0.0 ± 0.0
3.594ValAsp: 3.594 ± 1.294
1.797ValGlu: 1.797 ± 1.789
2.695ValPhe: 2.695 ± 1.313
2.695ValGly: 2.695 ± 1.812
4.492ValHis: 4.492 ± 1.305
5.391ValIle: 5.391 ± 1.775
4.492ValLys: 4.492 ± 2.877
5.391ValLeu: 5.391 ± 1.114
1.797ValMet: 1.797 ± 1.594
2.695ValAsn: 2.695 ± 1.346
4.492ValPro: 4.492 ± 1.331
4.492ValGln: 4.492 ± 1.549
2.695ValArg: 2.695 ± 2.391
2.695ValSer: 2.695 ± 1.176
4.492ValThr: 4.492 ± 2.877
2.695ValVal: 2.695 ± 1.35
0.0ValTrp: 0.0 ± 0.0
4.492ValTyr: 4.492 ± 2.001
0.0ValXaa: 0.0 ± 0.0
Trp
3.594TrpAla: 3.594 ± 1.7
0.0TrpCys: 0.0 ± 0.0
0.898TrpAsp: 0.898 ± 0.894
0.898TrpGlu: 0.898 ± 0.832
0.0TrpPhe: 0.0 ± 0.0
0.898TrpGly: 0.898 ± 0.667
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.898TrpLys: 0.898 ± 0.832
0.0TrpLeu: 0.0 ± 0.0
0.898TrpMet: 0.898 ± 0.797
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.898TrpGln: 0.898 ± 0.667
0.898TrpArg: 0.898 ± 0.878
2.695TrpSer: 2.695 ± 1.526
0.898TrpThr: 0.898 ± 0.832
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.797TrpTyr: 1.797 ± 0.706
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.695TyrAla: 2.695 ± 1.35
0.0TyrCys: 0.0 ± 0.0
1.797TyrAsp: 1.797 ± 1.077
0.898TyrGlu: 0.898 ± 0.797
3.594TyrPhe: 3.594 ± 0.899
1.797TyrGly: 1.797 ± 0.706
0.0TyrHis: 0.0 ± 0.0
4.492TyrIle: 4.492 ± 1.935
0.898TyrLys: 0.898 ± 0.667
3.594TyrLeu: 3.594 ± 1.204
1.797TyrMet: 1.797 ± 1.028
2.695TyrAsn: 2.695 ± 0.793
1.797TyrPro: 1.797 ± 0.979
0.898TyrGln: 0.898 ± 0.797
3.594TyrArg: 3.594 ± 1.748
3.594TyrSer: 3.594 ± 1.096
0.0TyrThr: 0.0 ± 0.0
3.594TyrVal: 3.594 ± 1.748
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1114 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski