Amino acid dipepetide frequency for Coprinellus micaceus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.491AlaAla: 7.491 ± 0.046	1.185AlaCys: 1.185 ± 0.012	3.634AlaAsp: 3.634 ± 0.021	4.5AlaGlu: 4.5 ± 0.034	3.214AlaPhe: 3.214 ± 0.022	5.43AlaGly: 5.43 ± 0.029	2.017AlaHis: 2.017 ± 0.015	4.014AlaIle: 4.014 ± 0.025	3.813AlaLys: 3.813 ± 0.024	8.231AlaLeu: 8.231 ± 0.037	1.787AlaMet: 1.787 ± 0.015	2.679AlaAsn: 2.679 ± 0.02	5.394AlaPro: 5.394 ± 0.039	3.206AlaGln: 3.206 ± 0.022	5.11AlaArg: 5.11 ± 0.027	7.489AlaSer: 7.489 ± 0.038	5.087AlaThr: 5.087 ± 0.027	5.087AlaVal: 5.087 ± 0.03	1.178AlaTrp: 1.178 ± 0.012	2.061AlaTyr: 2.061 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	1.017CysAla: 1.017 ± 0.011	0.274CysCys: 0.274 ± 0.007	0.73CysAsp: 0.73 ± 0.01	0.653CysGlu: 0.653 ± 0.009	0.57CysPhe: 0.57 ± 0.01	1.032CysGly: 1.032 ± 0.013	0.444CysHis: 0.444 ± 0.008	0.692CysIle: 0.692 ± 0.009	0.571CysLys: 0.571 ± 0.008	1.424CysLeu: 1.424 ± 0.014	0.291CysMet: 0.291 ± 0.005	0.457CysAsn: 0.457 ± 0.007	0.98CysPro: 0.98 ± 0.015	0.528CysGln: 0.528 ± 0.009	0.995CysArg: 0.995 ± 0.01	1.153CysSer: 1.153 ± 0.013	0.823CysThr: 0.823 ± 0.01	0.869CysVal: 0.869 ± 0.012	0.253CysTrp: 0.253 ± 0.005	0.354CysTyr: 0.354 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.455AspAla: 4.455 ± 0.021	0.616AspCys: 0.616 ± 0.009	3.957AspAsp: 3.957 ± 0.032	4.147AspGlu: 4.147 ± 0.028	2.005AspPhe: 2.005 ± 0.016	3.992AspGly: 3.992 ± 0.025	1.242AspHis: 1.242 ± 0.013	2.882AspIle: 2.882 ± 0.019	1.985AspLys: 1.985 ± 0.018	5.049AspLeu: 5.049 ± 0.029	1.117AspMet: 1.117 ± 0.011	1.535AspAsn: 1.535 ± 0.013	3.559AspPro: 3.559 ± 0.021	1.522AspGln: 1.522 ± 0.013	3.0AspArg: 3.0 ± 0.022	3.979AspSer: 3.979 ± 0.023	2.832AspThr: 2.832 ± 0.017	3.57AspVal: 3.57 ± 0.022	0.885AspTrp: 0.885 ± 0.011	1.405AspTyr: 1.405 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	5.089GluAla: 5.089 ± 0.034	0.779GluCys: 0.779 ± 0.009	4.124GluAsp: 4.124 ± 0.027	5.456GluGlu: 5.456 ± 0.058	1.772GluPhe: 1.772 ± 0.013	4.4GluGly: 4.4 ± 0.027	1.42GluHis: 1.42 ± 0.014	2.579GluIle: 2.579 ± 0.019	3.036GluLys: 3.036 ± 0.022	5.083GluLeu: 5.083 ± 0.029	1.265GluMet: 1.265 ± 0.013	1.804GluAsn: 1.804 ± 0.015	2.781GluPro: 2.781 ± 0.022	1.997GluGln: 1.997 ± 0.017	4.302GluArg: 4.302 ± 0.035	4.007GluSer: 4.007 ± 0.021	2.956GluThr: 2.956 ± 0.018	3.826GluVal: 3.826 ± 0.025	0.992GluTrp: 0.992 ± 0.011	1.53GluTyr: 1.53 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	2.895PheAla: 2.895 ± 0.02	0.56PheCys: 0.56 ± 0.009	2.198PheAsp: 2.198 ± 0.016	2.057PheGlu: 2.057 ± 0.017	1.586PhePhe: 1.586 ± 0.016	2.58PheGly: 2.58 ± 0.021	1.034PheHis: 1.034 ± 0.012	1.713PheIle: 1.713 ± 0.016	1.566PheLys: 1.566 ± 0.015	3.585PheLeu: 3.585 ± 0.023	0.718PheMet: 0.718 ± 0.01	1.351PheAsn: 1.351 ± 0.014	2.249PhePro: 2.249 ± 0.017	1.32PheGln: 1.32 ± 0.013	2.088PheArg: 2.088 ± 0.017	3.093PheSer: 3.093 ± 0.019	2.147PheThr: 2.147 ± 0.015	2.399PheVal: 2.399 ± 0.018	0.562PheTrp: 0.562 ± 0.008	1.033PheTyr: 1.033 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	5.132GlyAla: 5.132 ± 0.03	1.032GlyCys: 1.032 ± 0.013	3.61GlyAsp: 3.61 ± 0.021	3.932GlyGlu: 3.932 ± 0.026	2.465GlyPhe: 2.465 ± 0.018	5.977GlyGly: 5.977 ± 0.052	1.827GlyHis: 1.827 ± 0.016	3.051GlyIle: 3.051 ± 0.022	3.362GlyLys: 3.362 ± 0.023	5.825GlyLeu: 5.825 ± 0.03	1.522GlyMet: 1.522 ± 0.018	2.294GlyAsn: 2.294 ± 0.018	3.679GlyPro: 3.679 ± 0.026	2.323GlyGln: 2.323 ± 0.018	4.591GlyArg: 4.591 ± 0.027	5.977GlySer: 5.977 ± 0.031	3.995GlyThr: 3.995 ± 0.025	4.535GlyVal: 4.535 ± 0.023	1.232GlyTrp: 1.232 ± 0.012	1.885GlyTyr: 1.885 ± 0.015	0.0GlyXaa: 0.0 ± 0.0
His	1.995HisAla: 1.995 ± 0.016	0.405HisCys: 0.405 ± 0.007	1.293HisAsp: 1.293 ± 0.012	1.212HisGlu: 1.212 ± 0.014	1.05HisPhe: 1.05 ± 0.013	1.743HisGly: 1.743 ± 0.015	1.007HisHis: 1.007 ± 0.013	1.361HisIle: 1.361 ± 0.014	0.899HisLys: 0.899 ± 0.011	2.896HisLeu: 2.896 ± 0.022	0.471HisMet: 0.471 ± 0.007	0.815HisAsn: 0.815 ± 0.009	2.269HisPro: 2.269 ± 0.019	1.026HisGln: 1.026 ± 0.011	1.917HisArg: 1.917 ± 0.015	2.234HisSer: 2.234 ± 0.018	1.551HisThr: 1.551 ± 0.014	1.508HisVal: 1.508 ± 0.013	0.409HisTrp: 0.409 ± 0.007	0.707HisTyr: 0.707 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.891IleAla: 3.891 ± 0.023	0.684IleCys: 0.684 ± 0.009	2.504IleAsp: 2.504 ± 0.02	2.566IleGlu: 2.566 ± 0.018	1.784IlePhe: 1.784 ± 0.017	2.701IleGly: 2.701 ± 0.019	1.293IleHis: 1.293 ± 0.012	2.092IleIle: 2.092 ± 0.016	1.731IleLys: 1.731 ± 0.015	4.485IleLeu: 4.485 ± 0.028	0.842IleMet: 0.842 ± 0.009	1.423IleAsn: 1.423 ± 0.015	3.369IlePro: 3.369 ± 0.02	1.809IleGln: 1.809 ± 0.015	2.943IleArg: 2.943 ± 0.019	3.719IleSer: 3.719 ± 0.023	2.523IleThr: 2.523 ± 0.021	3.065IleVal: 3.065 ± 0.021	0.701IleTrp: 0.701 ± 0.008	1.203IleTyr: 1.203 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	4.214LysAla: 4.214 ± 0.027	0.557LysCys: 0.557 ± 0.009	2.486LysAsp: 2.486 ± 0.018	3.185LysGlu: 3.185 ± 0.027	1.341LysPhe: 1.341 ± 0.014	3.116LysGly: 3.116 ± 0.02	1.116LysHis: 1.116 ± 0.011	1.846LysIle: 1.846 ± 0.016	2.898LysLys: 2.898 ± 0.031	3.793LysLeu: 3.793 ± 0.024	0.849LysMet: 0.849 ± 0.01	1.414LysAsn: 1.414 ± 0.013	2.594LysPro: 2.594 ± 0.021	1.543LysGln: 1.543 ± 0.014	3.493LysArg: 3.493 ± 0.024	3.173LysSer: 3.173 ± 0.024	2.446LysThr: 2.446 ± 0.017	2.793LysVal: 2.793 ± 0.022	0.665LysTrp: 0.665 ± 0.009	1.164LysTyr: 1.164 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	7.902LeuAla: 7.902 ± 0.032	1.414LeuCys: 1.414 ± 0.013	5.205LeuAsp: 5.205 ± 0.025	5.847LeuGlu: 5.847 ± 0.034	3.341LeuPhe: 3.341 ± 0.02	5.957LeuGly: 5.957 ± 0.031	2.631LeuHis: 2.631 ± 0.02	3.651LeuIle: 3.651 ± 0.024	4.266LeuLys: 4.266 ± 0.023	8.555LeuLeu: 8.555 ± 0.044	1.612LeuMet: 1.612 ± 0.013	3.128LeuAsn: 3.128 ± 0.021	6.689LeuPro: 6.689 ± 0.032	3.718LeuGln: 3.718 ± 0.024	6.428LeuArg: 6.428 ± 0.03	8.052LeuSer: 8.052 ± 0.033	5.29LeuThr: 5.29 ± 0.026	5.737LeuVal: 5.737 ± 0.03	1.358LeuTrp: 1.358 ± 0.013	2.355LeuTyr: 2.355 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.804MetAla: 1.804 ± 0.016	0.262MetCys: 0.262 ± 0.005	1.184MetAsp: 1.184 ± 0.012	1.192MetGlu: 1.192 ± 0.012	0.722MetPhe: 0.722 ± 0.009	1.378MetGly: 1.378 ± 0.013	0.502MetHis: 0.502 ± 0.008	0.775MetIle: 0.775 ± 0.01	0.947MetLys: 0.947 ± 0.01	1.7MetLeu: 1.7 ± 0.015	0.441MetMet: 0.441 ± 0.008	0.692MetAsn: 0.692 ± 0.008	1.233MetPro: 1.233 ± 0.013	0.728MetGln: 0.728 ± 0.009	1.256MetArg: 1.256 ± 0.012	1.793MetSer: 1.793 ± 0.013	1.138MetThr: 1.138 ± 0.011	1.222MetVal: 1.222 ± 0.012	0.278MetTrp: 0.278 ± 0.006	0.474MetTyr: 0.474 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.94AsnAla: 2.94 ± 0.018	0.415AsnCys: 0.415 ± 0.008	1.663AsnAsp: 1.663 ± 0.014	1.73AsnGlu: 1.73 ± 0.014	1.166AsnPhe: 1.166 ± 0.013	2.524AsnGly: 2.524 ± 0.022	0.873AsnHis: 0.873 ± 0.012	1.689AsnIle: 1.689 ± 0.015	1.229AsnLys: 1.229 ± 0.014	3.3AsnLeu: 3.3 ± 0.023	0.664AsnMet: 0.664 ± 0.009	1.117AsnAsn: 1.117 ± 0.013	2.563AsnPro: 2.563 ± 0.019	1.066AsnGln: 1.066 ± 0.01	1.919AsnArg: 1.919 ± 0.015	2.483AsnSer: 2.483 ± 0.019	1.99AsnThr: 1.99 ± 0.018	2.207AsnVal: 2.207 ± 0.015	0.497AsnTrp: 0.497 ± 0.008	0.847AsnTyr: 0.847 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	5.608ProAla: 5.608 ± 0.039	0.79ProCys: 0.79 ± 0.011	3.117ProAsp: 3.117 ± 0.019	3.69ProGlu: 3.69 ± 0.02	2.421ProPhe: 2.421 ± 0.018	4.286ProGly: 4.286 ± 0.031	1.801ProHis: 1.801 ± 0.018	2.774ProIle: 2.774 ± 0.018	2.713ProLys: 2.713 ± 0.021	5.774ProLeu: 5.774 ± 0.03	1.142ProMet: 1.142 ± 0.014	2.39ProAsn: 2.39 ± 0.018	6.948ProPro: 6.948 ± 0.064	2.619ProGln: 2.619 ± 0.024	4.134ProArg: 4.134 ± 0.027	7.761ProSer: 7.761 ± 0.048	4.894ProThr: 4.894 ± 0.037	3.774ProVal: 3.774 ± 0.026	0.845ProTrp: 0.845 ± 0.01	1.557ProTyr: 1.557 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.273GlnAla: 3.273 ± 0.02	0.549GlnCys: 0.549 ± 0.008	1.864GlnAsp: 1.864 ± 0.015	2.161GlnGlu: 2.161 ± 0.019	1.249GlnPhe: 1.249 ± 0.012	2.431GlnGly: 2.431 ± 0.017	1.12GlnHis: 1.12 ± 0.012	1.542GlnIle: 1.542 ± 0.013	1.575GlnLys: 1.575 ± 0.014	3.309GlnLeu: 3.309 ± 0.021	0.742GlnMet: 0.742 ± 0.01	1.214GlnAsn: 1.214 ± 0.014	2.487GlnPro: 2.487 ± 0.026	1.876GlnGln: 1.876 ± 0.029	2.672GlnArg: 2.672 ± 0.022	2.828GlnSer: 2.828 ± 0.018	2.091GlnThr: 2.091 ± 0.016	2.166GlnVal: 2.166 ± 0.017	0.594GlnTrp: 0.594 ± 0.009	1.021GlnTyr: 1.021 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	5.093ArgAla: 5.093 ± 0.025	1.066ArgCys: 1.066 ± 0.012	3.335ArgAsp: 3.335 ± 0.024	3.901ArgGlu: 3.901 ± 0.03	2.464ArgPhe: 2.464 ± 0.019	4.215ArgGly: 4.215 ± 0.024	1.787ArgHis: 1.787 ± 0.016	3.022ArgIle: 3.022 ± 0.019	3.354ArgLys: 3.354 ± 0.022	6.156ArgLeu: 6.156 ± 0.028	1.392ArgMet: 1.392 ± 0.015	2.165ArgAsn: 2.165 ± 0.015	4.037ArgPro: 4.037 ± 0.025	2.425ArgGln: 2.425 ± 0.022	6.052ArgArg: 6.052 ± 0.038	5.459ArgSer: 5.459 ± 0.033	3.805ArgThr: 3.805 ± 0.024	4.06ArgVal: 4.06 ± 0.022	1.135ArgTrp: 1.135 ± 0.012	1.771ArgTyr: 1.771 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.722SerAla: 6.722 ± 0.037	1.061SerCys: 1.061 ± 0.013	4.121SerAsp: 4.121 ± 0.025	3.992SerGlu: 3.992 ± 0.021	3.232SerPhe: 3.232 ± 0.021	5.723SerGly: 5.723 ± 0.035	2.17SerHis: 2.17 ± 0.017	3.927SerIle: 3.927 ± 0.023	3.607SerLys: 3.607 ± 0.023	8.236SerLeu: 8.236 ± 0.031	1.645SerMet: 1.645 ± 0.016	2.85SerAsn: 2.85 ± 0.022	6.639SerPro: 6.639 ± 0.054	3.16SerGln: 3.16 ± 0.02	5.573SerArg: 5.573 ± 0.028	9.891SerSer: 9.891 ± 0.071	6.211SerThr: 6.211 ± 0.04	4.839SerVal: 4.839 ± 0.028	1.152SerTrp: 1.152 ± 0.012	1.936SerTyr: 1.936 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	4.749ThrAla: 4.749 ± 0.027	0.847ThrCys: 0.847 ± 0.012	2.516ThrAsp: 2.516 ± 0.015	2.752ThrGlu: 2.752 ± 0.019	2.378ThrPhe: 2.378 ± 0.019	3.892ThrGly: 3.892 ± 0.027	1.589ThrHis: 1.589 ± 0.014	2.956ThrIle: 2.956 ± 0.019	2.413ThrLys: 2.413 ± 0.019	5.922ThrLeu: 5.922 ± 0.028	1.132ThrMet: 1.132 ± 0.011	1.918ThrAsn: 1.918 ± 0.016	5.125ThrPro: 5.125 ± 0.037	2.099ThrGln: 2.099 ± 0.018	3.668ThrArg: 3.668 ± 0.02	5.806ThrSer: 5.806 ± 0.035	4.366ThrThr: 4.366 ± 0.032	3.692ThrVal: 3.692 ± 0.02	0.846ThrTrp: 0.846 ± 0.01	1.498ThrTyr: 1.498 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	5.132ValAla: 5.132 ± 0.026	0.959ValCys: 0.959 ± 0.01	3.704ValAsp: 3.704 ± 0.021	3.978ValGlu: 3.978 ± 0.032	2.365ValPhe: 2.365 ± 0.019	4.088ValGly: 4.088 ± 0.026	1.689ValHis: 1.689 ± 0.015	2.737ValIle: 2.737 ± 0.019	2.89ValLys: 2.89 ± 0.021	5.943ValLeu: 5.943 ± 0.028	1.195ValMet: 1.195 ± 0.011	2.079ValAsn: 2.079 ± 0.017	4.066ValPro: 4.066 ± 0.027	2.365ValGln: 2.365 ± 0.018	3.728ValArg: 3.728 ± 0.023	4.71ValSer: 4.71 ± 0.025	3.503ValThr: 3.503 ± 0.019	4.559ValVal: 4.559 ± 0.026	0.998ValTrp: 0.998 ± 0.012	1.742ValTyr: 1.742 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	1.168TrpAla: 1.168 ± 0.013	0.248TrpCys: 0.248 ± 0.005	0.955TrpAsp: 0.955 ± 0.011	0.914TrpGlu: 0.914 ± 0.012	0.556TrpPhe: 0.556 ± 0.01	0.961TrpGly: 0.961 ± 0.012	0.384TrpHis: 0.384 ± 0.006	0.762TrpIle: 0.762 ± 0.01	0.898TrpLys: 0.898 ± 0.01	1.312TrpLeu: 1.312 ± 0.014	0.373TrpMet: 0.373 ± 0.008	0.639TrpAsn: 0.639 ± 0.009	0.698TrpPro: 0.698 ± 0.011	0.479TrpGln: 0.479 ± 0.008	1.157TrpArg: 1.157 ± 0.012	1.138TrpSer: 1.138 ± 0.01	0.93TrpThr: 0.93 ± 0.01	0.982TrpVal: 0.982 ± 0.012	0.331TrpTrp: 0.331 ± 0.006	0.419TrpTyr: 0.419 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.038TyrAla: 2.038 ± 0.019	0.407TyrCys: 0.407 ± 0.008	1.534TyrAsp: 1.534 ± 0.015	1.335TyrGlu: 1.335 ± 0.013	1.049TyrPhe: 1.049 ± 0.01	1.82TyrGly: 1.82 ± 0.019	0.819TyrHis: 0.819 ± 0.009	1.266TyrIle: 1.266 ± 0.011	0.935TyrLys: 0.935 ± 0.013	2.558TyrLeu: 2.558 ± 0.018	0.522TyrMet: 0.522 ± 0.007	0.917TyrAsn: 0.917 ± 0.01	1.681TyrPro: 1.681 ± 0.015	0.953TyrGln: 0.953 ± 0.011	1.672TyrArg: 1.672 ± 0.016	1.94TyrSer: 1.94 ± 0.018	1.585TyrThr: 1.585 ± 0.014	1.541TyrVal: 1.541 ± 0.014	0.391TyrTrp: 0.391 ± 0.007	0.81TyrTyr: 0.81 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 23011 proteins (8897202 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---