Amino acid dipepetide frequency for Lutimaribacter litoralis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.661AlaAla: 15.661 ± 0.153	1.027AlaCys: 1.027 ± 0.03	7.238AlaAsp: 7.238 ± 0.084	7.441AlaGlu: 7.441 ± 0.095	4.171AlaPhe: 4.171 ± 0.064	10.126AlaGly: 10.126 ± 0.102	2.261AlaHis: 2.261 ± 0.043	5.828AlaIle: 5.828 ± 0.074	4.247AlaLys: 4.247 ± 0.068	13.096AlaLeu: 13.096 ± 0.129	3.705AlaMet: 3.705 ± 0.057	2.852AlaAsn: 2.852 ± 0.049	5.392AlaPro: 5.392 ± 0.07	4.951AlaGln: 4.951 ± 0.066	7.734AlaArg: 7.734 ± 0.1	5.111AlaSer: 5.111 ± 0.064	5.726AlaThr: 5.726 ± 0.078	8.319AlaVal: 8.319 ± 0.086	1.294AlaTrp: 1.294 ± 0.03	2.545AlaTyr: 2.545 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	1.048CysAla: 1.048 ± 0.03	0.119CysCys: 0.119 ± 0.01	0.622CysAsp: 0.622 ± 0.022	0.406CysGlu: 0.406 ± 0.017	0.359CysPhe: 0.359 ± 0.014	0.947CysGly: 0.947 ± 0.027	0.274CysHis: 0.274 ± 0.015	0.412CysIle: 0.412 ± 0.019	0.247CysLys: 0.247 ± 0.015	0.845CysLeu: 0.845 ± 0.029	0.204CysMet: 0.204 ± 0.013	0.239CysAsn: 0.239 ± 0.013	0.534CysPro: 0.534 ± 0.023	0.281CysGln: 0.281 ± 0.016	0.551CysArg: 0.551 ± 0.024	0.47CysSer: 0.47 ± 0.018	0.434CysThr: 0.434 ± 0.017	0.624CysVal: 0.624 ± 0.024	0.101CysTrp: 0.101 ± 0.009	0.23CysTyr: 0.23 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.064AspAla: 7.064 ± 0.089	0.543AspCys: 0.543 ± 0.023	3.588AspAsp: 3.588 ± 0.085	3.347AspGlu: 3.347 ± 0.062	2.266AspPhe: 2.266 ± 0.047	5.603AspGly: 5.603 ± 0.084	1.468AspHis: 1.468 ± 0.04	3.226AspIle: 3.226 ± 0.058	1.954AspLys: 1.954 ± 0.04	6.59AspLeu: 6.59 ± 0.074	2.054AspMet: 2.054 ± 0.039	1.346AspAsn: 1.346 ± 0.04	3.537AspPro: 3.537 ± 0.055	2.2AspGln: 2.2 ± 0.041	4.228AspArg: 4.228 ± 0.059	2.252AspSer: 2.252 ± 0.047	3.266AspThr: 3.266 ± 0.066	4.383AspVal: 4.383 ± 0.062	1.214AspTrp: 1.214 ± 0.033	1.699AspTyr: 1.699 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	6.666GluAla: 6.666 ± 0.102	0.414GluCys: 0.414 ± 0.018	3.257GluAsp: 3.257 ± 0.064	3.145GluGlu: 3.145 ± 0.071	1.832GluPhe: 1.832 ± 0.042	4.297GluGly: 4.297 ± 0.064	1.039GluHis: 1.039 ± 0.033	3.431GluIle: 3.431 ± 0.051	2.398GluLys: 2.398 ± 0.05	5.178GluLeu: 5.178 ± 0.069	1.738GluMet: 1.738 ± 0.042	1.912GluAsn: 1.912 ± 0.039	2.29GluPro: 2.29 ± 0.047	2.243GluGln: 2.243 ± 0.045	3.776GluArg: 3.776 ± 0.063	2.022GluSer: 2.022 ± 0.043	3.734GluThr: 3.734 ± 0.052	3.784GluVal: 3.784 ± 0.064	0.756GluTrp: 0.756 ± 0.022	1.181GluTyr: 1.181 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.353PheAla: 4.353 ± 0.06	0.412PheCys: 0.412 ± 0.016	2.804PheAsp: 2.804 ± 0.053	2.02PheGlu: 2.02 ± 0.043	1.437PhePhe: 1.437 ± 0.035	3.646PheGly: 3.646 ± 0.059	0.788PheHis: 0.788 ± 0.027	1.701PheIle: 1.701 ± 0.044	1.049PheLys: 1.049 ± 0.028	3.474PheLeu: 3.474 ± 0.066	0.911PheMet: 0.911 ± 0.031	1.14PheAsn: 1.14 ± 0.028	1.569PhePro: 1.569 ± 0.04	1.144PheGln: 1.144 ± 0.033	2.138PheArg: 2.138 ± 0.035	2.151PheSer: 2.151 ± 0.039	2.124PheThr: 2.124 ± 0.04	2.662PheVal: 2.662 ± 0.05	0.545PheTrp: 0.545 ± 0.021	0.964PheTyr: 0.964 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	9.597GlyAla: 9.597 ± 0.098	0.819GlyCys: 0.819 ± 0.028	4.903GlyAsp: 4.903 ± 0.077	4.184GlyGlu: 4.184 ± 0.061	3.711GlyPhe: 3.711 ± 0.056	7.485GlyGly: 7.485 ± 0.111	1.902GlyHis: 1.902 ± 0.048	4.606GlyIle: 4.606 ± 0.066	3.475GlyLys: 3.475 ± 0.066	9.145GlyLeu: 9.145 ± 0.096	2.81GlyMet: 2.81 ± 0.051	2.339GlyAsn: 2.339 ± 0.069	3.619GlyPro: 3.619 ± 0.056	3.512GlyGln: 3.512 ± 0.062	5.381GlyArg: 5.381 ± 0.07	4.089GlySer: 4.089 ± 0.065	4.564GlyThr: 4.564 ± 0.07	6.648GlyVal: 6.648 ± 0.085	1.449GlyTrp: 1.449 ± 0.037	2.409GlyTyr: 2.409 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.269HisAla: 2.269 ± 0.048	0.243HisCys: 0.243 ± 0.013	1.334HisAsp: 1.334 ± 0.039	0.977HisGlu: 0.977 ± 0.032	0.816HisPhe: 0.816 ± 0.026	1.905HisGly: 1.905 ± 0.038	0.579HisHis: 0.579 ± 0.023	1.081HisIle: 1.081 ± 0.033	0.593HisLys: 0.593 ± 0.021	2.136HisLeu: 2.136 ± 0.049	0.608HisMet: 0.608 ± 0.023	0.534HisAsn: 0.534 ± 0.019	1.53HisPro: 1.53 ± 0.038	0.637HisGln: 0.637 ± 0.024	1.274HisArg: 1.274 ± 0.036	0.982HisSer: 0.982 ± 0.029	0.949HisThr: 0.949 ± 0.03	1.508HisVal: 1.508 ± 0.033	0.36HisTrp: 0.36 ± 0.017	0.577HisTyr: 0.577 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	6.883IleAla: 6.883 ± 0.08	0.639IleCys: 0.639 ± 0.025	3.337IleAsp: 3.337 ± 0.063	3.373IleGlu: 3.373 ± 0.052	1.779IlePhe: 1.779 ± 0.043	4.848IleGly: 4.848 ± 0.078	1.016IleHis: 1.016 ± 0.028	2.329IleIle: 2.329 ± 0.055	1.567IleLys: 1.567 ± 0.036	4.961IleLeu: 4.961 ± 0.07	1.188IleMet: 1.188 ± 0.037	1.431IleAsn: 1.431 ± 0.037	2.651IlePro: 2.651 ± 0.047	1.496IleGln: 1.496 ± 0.032	3.323IleArg: 3.323 ± 0.045	3.083IleSer: 3.083 ± 0.054	3.119IleThr: 3.119 ± 0.053	3.763IleVal: 3.763 ± 0.064	0.822IleTrp: 0.822 ± 0.031	1.251IleTyr: 1.251 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.214LysAla: 4.214 ± 0.068	0.202LysCys: 0.202 ± 0.012	1.979LysAsp: 1.979 ± 0.039	1.693LysGlu: 1.693 ± 0.039	1.043LysPhe: 1.043 ± 0.029	2.929LysGly: 2.929 ± 0.058	0.706LysHis: 0.706 ± 0.027	1.877LysIle: 1.877 ± 0.036	1.389LysLys: 1.389 ± 0.042	3.425LysLeu: 3.425 ± 0.059	1.078LysMet: 1.078 ± 0.031	0.925LysAsn: 0.925 ± 0.028	2.037LysPro: 2.037 ± 0.049	1.159LysGln: 1.159 ± 0.032	2.454LysArg: 2.454 ± 0.055	1.946LysSer: 1.946 ± 0.041	2.239LysThr: 2.239 ± 0.043	2.419LysVal: 2.419 ± 0.056	0.45LysTrp: 0.45 ± 0.021	0.788LysTyr: 0.788 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	12.147LeuAla: 12.147 ± 0.126	0.963LeuCys: 0.963 ± 0.031	6.044LeuAsp: 6.044 ± 0.084	5.162LeuGlu: 5.162 ± 0.064	3.616LeuPhe: 3.616 ± 0.074	8.406LeuGly: 8.406 ± 0.092	2.002LeuHis: 2.002 ± 0.042	5.487LeuIle: 5.487 ± 0.078	3.492LeuLys: 3.492 ± 0.053	8.939LeuLeu: 8.939 ± 0.125	2.809LeuMet: 2.809 ± 0.052	3.092LeuAsn: 3.092 ± 0.052	5.626LeuPro: 5.626 ± 0.074	2.797LeuGln: 2.797 ± 0.05	6.785LeuArg: 6.785 ± 0.08	6.85LeuSer: 6.85 ± 0.088	6.348LeuThr: 6.348 ± 0.082	6.552LeuVal: 6.552 ± 0.091	1.275LeuTrp: 1.275 ± 0.037	2.028LeuTyr: 2.028 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	3.503MetAla: 3.503 ± 0.048	0.198MetCys: 0.198 ± 0.014	1.56MetAsp: 1.56 ± 0.041	1.429MetGlu: 1.429 ± 0.039	0.856MetPhe: 0.856 ± 0.026	2.505MetGly: 2.505 ± 0.051	0.466MetHis: 0.466 ± 0.022	1.646MetIle: 1.646 ± 0.038	1.271MetLys: 1.271 ± 0.038	2.72MetLeu: 2.72 ± 0.051	0.89MetMet: 0.89 ± 0.026	0.955MetAsn: 0.955 ± 0.029	1.595MetPro: 1.595 ± 0.037	1.163MetGln: 1.163 ± 0.03	1.89MetArg: 1.89 ± 0.037	1.745MetSer: 1.745 ± 0.041	2.272MetThr: 2.272 ± 0.044	1.904MetVal: 1.904 ± 0.042	0.26MetTrp: 0.26 ± 0.014	0.414MetTyr: 0.414 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.325AsnAla: 3.325 ± 0.055	0.302AsnCys: 0.302 ± 0.016	1.629AsnAsp: 1.629 ± 0.051	1.24AsnGlu: 1.24 ± 0.033	0.992AsnPhe: 0.992 ± 0.027	2.736AsnGly: 2.736 ± 0.054	0.573AsnHis: 0.573 ± 0.021	1.483AsnIle: 1.483 ± 0.037	0.818AsnLys: 0.818 ± 0.027	2.694AsnLeu: 2.694 ± 0.052	0.771AsnMet: 0.771 ± 0.027	0.706AsnAsn: 0.706 ± 0.028	1.965AsnPro: 1.965 ± 0.045	0.779AsnGln: 0.779 ± 0.028	1.902AsnArg: 1.902 ± 0.045	1.269AsnSer: 1.269 ± 0.034	1.518AsnThr: 1.518 ± 0.039	1.983AsnVal: 1.983 ± 0.05	0.468AsnTrp: 0.468 ± 0.02	0.679AsnTyr: 0.679 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	5.669ProAla: 5.669 ± 0.082	0.351ProCys: 0.351 ± 0.017	4.175ProAsp: 4.175 ± 0.064	3.84ProGlu: 3.84 ± 0.066	1.902ProPhe: 1.902 ± 0.041	4.261ProGly: 4.261 ± 0.056	1.115ProHis: 1.115 ± 0.032	2.372ProIle: 2.372 ± 0.038	1.844ProLys: 1.844 ± 0.046	4.712ProLeu: 4.712 ± 0.066	1.375ProMet: 1.375 ± 0.034	1.458ProAsn: 1.458 ± 0.04	2.123ProPro: 2.123 ± 0.051	1.916ProGln: 1.916 ± 0.045	2.698ProArg: 2.698 ± 0.05	2.422ProSer: 2.422 ± 0.045	2.479ProThr: 2.479 ± 0.046	4.34ProVal: 4.34 ± 0.068	0.63ProTrp: 0.63 ± 0.025	1.178ProTyr: 1.178 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	4.681GlnAla: 4.681 ± 0.07	0.232GlnCys: 0.232 ± 0.014	2.071GlnAsp: 2.071 ± 0.042	1.731GlnGlu: 1.731 ± 0.042	1.177GlnPhe: 1.177 ± 0.034	2.86GlnGly: 2.86 ± 0.046	0.699GlnHis: 0.699 ± 0.024	2.256GlnIle: 2.256 ± 0.039	1.332GlnLys: 1.332 ± 0.037	2.91GlnLeu: 2.91 ± 0.055	1.202GlnMet: 1.202 ± 0.033	1.029GlnAsn: 1.029 ± 0.031	1.792GlnPro: 1.792 ± 0.038	1.279GlnGln: 1.279 ± 0.039	2.314GlnArg: 2.314 ± 0.039	1.835GlnSer: 1.835 ± 0.04	2.021GlnThr: 2.021 ± 0.045	2.789GlnVal: 2.789 ± 0.055	0.42GlnTrp: 0.42 ± 0.02	0.666GlnTyr: 0.666 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	7.301ArgAla: 7.301 ± 0.091	0.484ArgCys: 0.484 ± 0.021	4.132ArgAsp: 4.132 ± 0.064	3.432ArgGlu: 3.432 ± 0.053	2.643ArgPhe: 2.643 ± 0.042	4.491ArgGly: 4.491 ± 0.066	1.497ArgHis: 1.497 ± 0.033	3.788ArgIle: 3.788 ± 0.051	2.501ArgLys: 2.501 ± 0.052	6.931ArgLeu: 6.931 ± 0.088	1.965ArgMet: 1.965 ± 0.041	1.865ArgAsn: 1.865 ± 0.039	3.072ArgPro: 3.072 ± 0.05	2.403ArgGln: 2.403 ± 0.048	4.424ArgArg: 4.424 ± 0.067	3.02ArgSer: 3.02 ± 0.053	2.891ArgThr: 2.891 ± 0.044	4.585ArgVal: 4.585 ± 0.066	0.908ArgTrp: 0.908 ± 0.027	1.589ArgTyr: 1.589 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.549SerAla: 5.549 ± 0.068	0.448SerCys: 0.448 ± 0.02	3.211SerAsp: 3.211 ± 0.059	2.635SerGlu: 2.635 ± 0.05	2.176SerPhe: 2.176 ± 0.043	5.351SerGly: 5.351 ± 0.066	1.097SerHis: 1.097 ± 0.026	2.474SerIle: 2.474 ± 0.053	1.618SerLys: 1.618 ± 0.035	5.004SerLeu: 5.004 ± 0.053	1.359SerMet: 1.359 ± 0.034	1.373SerAsn: 1.373 ± 0.042	2.576SerPro: 2.576 ± 0.049	1.587SerGln: 1.587 ± 0.04	3.014SerArg: 3.014 ± 0.051	2.569SerSer: 2.569 ± 0.057	2.452SerThr: 2.452 ± 0.055	3.855SerVal: 3.855 ± 0.059	0.656SerTrp: 0.656 ± 0.024	1.375SerTyr: 1.375 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	6.33ThrAla: 6.33 ± 0.096	0.503ThrCys: 0.503 ± 0.021	3.285ThrAsp: 3.285 ± 0.055	3.012ThrGlu: 3.012 ± 0.048	1.911ThrPhe: 1.911 ± 0.037	5.486ThrGly: 5.486 ± 0.083	1.204ThrHis: 1.204 ± 0.03	2.816ThrIle: 2.816 ± 0.051	1.599ThrLys: 1.599 ± 0.04	5.987ThrLeu: 5.987 ± 0.082	1.291ThrMet: 1.291 ± 0.031	1.462ThrAsn: 1.462 ± 0.036	3.644ThrPro: 3.644 ± 0.059	1.856ThrGln: 1.856 ± 0.042	3.502ThrArg: 3.502 ± 0.058	2.567ThrSer: 2.567 ± 0.05	2.895ThrThr: 2.895 ± 0.059	4.258ThrVal: 4.258 ± 0.065	0.626ThrTrp: 0.626 ± 0.023	1.31ThrTyr: 1.31 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	8.437ValAla: 8.437 ± 0.094	0.661ValCys: 0.661 ± 0.026	4.111ValAsp: 4.111 ± 0.06	4.122ValGlu: 4.122 ± 0.061	2.887ValPhe: 2.887 ± 0.055	5.352ValGly: 5.352 ± 0.077	1.305ValHis: 1.305 ± 0.033	4.357ValIle: 4.357 ± 0.066	2.409ValLys: 2.409 ± 0.051	7.644ValLeu: 7.644 ± 0.091	2.32ValMet: 2.32 ± 0.043	2.084ValAsn: 2.084 ± 0.044	3.516ValPro: 3.516 ± 0.061	2.515ValGln: 2.515 ± 0.054	4.004ValArg: 4.004 ± 0.056	4.124ValSer: 4.124 ± 0.069	4.602ValThr: 4.602 ± 0.074	5.562ValVal: 5.562 ± 0.094	0.96ValTrp: 0.96 ± 0.03	1.525ValTyr: 1.525 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.403TrpAla: 1.403 ± 0.034	0.127TrpCys: 0.127 ± 0.01	0.821TrpAsp: 0.821 ± 0.031	0.641TrpGlu: 0.641 ± 0.026	0.526TrpPhe: 0.526 ± 0.021	1.113TrpGly: 1.113 ± 0.034	0.338TrpHis: 0.338 ± 0.017	0.679TrpIle: 0.679 ± 0.026	0.505TrpLys: 0.505 ± 0.021	1.671TrpLeu: 1.671 ± 0.034	0.42TrpMet: 0.42 ± 0.019	0.445TrpAsn: 0.445 ± 0.018	0.664TrpPro: 0.664 ± 0.022	0.632TrpGln: 0.632 ± 0.022	0.971TrpArg: 0.971 ± 0.028	0.692TrpSer: 0.692 ± 0.022	0.736TrpThr: 0.736 ± 0.024	0.949TrpVal: 0.949 ± 0.029	0.197TrpTrp: 0.197 ± 0.014	0.253TrpTyr: 0.253 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.627TyrAla: 2.627 ± 0.048	0.262TyrCys: 0.262 ± 0.014	1.728TyrAsp: 1.728 ± 0.041	1.266TyrGlu: 1.266 ± 0.036	0.929TyrPhe: 0.929 ± 0.025	2.301TyrGly: 2.301 ± 0.05	0.563TyrHis: 0.563 ± 0.024	1.012TyrIle: 1.012 ± 0.03	0.642TyrLys: 0.642 ± 0.022	2.359TyrLeu: 2.359 ± 0.045	0.541TyrMet: 0.541 ± 0.023	0.64TyrAsn: 0.64 ± 0.022	1.123TyrPro: 1.123 ± 0.029	0.748TyrGln: 0.748 ± 0.021	1.561TyrArg: 1.561 ± 0.037	1.179TyrSer: 1.179 ± 0.028	1.176TyrThr: 1.176 ± 0.032	1.612TyrVal: 1.612 ± 0.039	0.39TyrTrp: 0.39 ± 0.018	0.589TyrTyr: 0.589 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4022 proteins (1232936 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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