Amino acid dipepetide frequency for Beilong virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.066AlaAla: 4.066 ± 0.543
1.017AlaCys: 1.017 ± 0.398
3.219AlaAsp: 3.219 ± 1.24
3.389AlaGlu: 3.389 ± 0.76
1.694AlaPhe: 1.694 ± 0.662
4.236AlaGly: 4.236 ± 1.432
1.694AlaHis: 1.694 ± 0.528
4.744AlaIle: 4.744 ± 0.862
3.05AlaLys: 3.05 ± 0.74
5.422AlaLeu: 5.422 ± 1.48
2.203AlaMet: 2.203 ± 0.674
2.711AlaAsn: 2.711 ± 0.646
2.542AlaPro: 2.542 ± 1.001
2.372AlaGln: 2.372 ± 0.443
3.897AlaArg: 3.897 ± 0.997
3.897AlaSer: 3.897 ± 0.414
3.389AlaThr: 3.389 ± 1.484
4.575AlaVal: 4.575 ± 0.934
1.186AlaTrp: 1.186 ± 0.269
2.372AlaTyr: 2.372 ± 0.376
0.0AlaXaa: 0.0 ± 0.0
Cys
1.355CysAla: 1.355 ± 0.705
0.508CysCys: 0.508 ± 0.199
0.678CysAsp: 0.678 ± 0.354
0.339CysGlu: 0.339 ± 0.229
1.186CysPhe: 1.186 ± 0.515
0.678CysGly: 0.678 ± 0.222
0.339CysHis: 0.339 ± 0.167
1.694CysIle: 1.694 ± 0.512
1.355CysLys: 1.355 ± 0.59
0.847CysLeu: 0.847 ± 0.276
0.0CysMet: 0.0 ± 0.0
0.508CysAsn: 0.508 ± 0.319
0.847CysPro: 0.847 ± 0.331
0.847CysGln: 0.847 ± 0.349
0.169CysArg: 0.169 ± 0.225
1.694CysSer: 1.694 ± 0.626
1.186CysThr: 1.186 ± 0.324
1.355CysVal: 1.355 ± 0.449
0.339CysTrp: 0.339 ± 0.229
1.525CysTyr: 1.525 ± 0.443
0.0CysXaa: 0.0 ± 0.0
Asp
3.219AspAla: 3.219 ± 1.198
0.678AspCys: 0.678 ± 0.307
3.05AspAsp: 3.05 ± 0.587
2.372AspGlu: 2.372 ± 0.793
2.88AspPhe: 2.88 ± 0.725
3.219AspGly: 3.219 ± 1.303
2.542AspHis: 2.542 ± 0.451
2.711AspIle: 2.711 ± 1.004
2.711AspLys: 2.711 ± 0.455
5.422AspLeu: 5.422 ± 0.987
2.033AspMet: 2.033 ± 0.63
1.186AspAsn: 1.186 ± 0.491
2.542AspPro: 2.542 ± 0.478
1.864AspGln: 1.864 ± 0.482
1.355AspArg: 1.355 ± 0.315
4.405AspSer: 4.405 ± 0.994
2.711AspThr: 2.711 ± 0.375
4.914AspVal: 4.914 ± 1.044
0.169AspTrp: 0.169 ± 0.114
3.219AspTyr: 3.219 ± 0.604
0.0AspXaa: 0.0 ± 0.0
Glu
2.88GluAla: 2.88 ± 0.584
1.864GluCys: 1.864 ± 0.543
3.558GluAsp: 3.558 ± 0.311
3.219GluGlu: 3.219 ± 0.4
2.372GluPhe: 2.372 ± 0.433
3.728GluGly: 3.728 ± 0.982
1.017GluHis: 1.017 ± 0.297
4.405GluIle: 4.405 ± 0.792
2.542GluLys: 2.542 ± 0.612
5.591GluLeu: 5.591 ± 0.855
1.525GluMet: 1.525 ± 0.283
2.88GluAsn: 2.88 ± 0.761
2.033GluPro: 2.033 ± 0.407
1.355GluGln: 1.355 ± 0.504
3.05GluArg: 3.05 ± 0.678
4.236GluSer: 4.236 ± 0.743
3.389GluThr: 3.389 ± 0.553
3.389GluVal: 3.389 ± 0.978
0.847GluTrp: 0.847 ± 0.205
2.711GluTyr: 2.711 ± 0.615
0.0GluXaa: 0.0 ± 0.0
Phe
2.88PheAla: 2.88 ± 0.501
0.847PheCys: 0.847 ± 0.572
1.017PheAsp: 1.017 ± 0.36
2.372PheGlu: 2.372 ± 0.617
1.355PhePhe: 1.355 ± 0.63
1.694PheGly: 1.694 ± 0.668
0.339PheHis: 0.339 ± 0.179
1.694PheIle: 1.694 ± 0.521
2.033PheLys: 2.033 ± 0.668
3.389PheLeu: 3.389 ± 1.13
1.186PheMet: 1.186 ± 0.444
2.542PheAsn: 2.542 ± 0.799
2.033PhePro: 2.033 ± 0.655
1.355PheGln: 1.355 ± 0.385
2.203PheArg: 2.203 ± 0.762
1.864PheSer: 1.864 ± 0.409
1.355PheThr: 1.355 ± 0.322
1.525PheVal: 1.525 ± 0.322
1.017PheTrp: 1.017 ± 0.295
1.017PheTyr: 1.017 ± 0.456
0.0PheXaa: 0.0 ± 0.0
Gly
4.744GlyAla: 4.744 ± 1.423
0.508GlyCys: 0.508 ± 0.361
3.558GlyAsp: 3.558 ± 0.616
2.711GlyGlu: 2.711 ± 0.432
2.033GlyPhe: 2.033 ± 1.021
5.93GlyGly: 5.93 ± 2.042
2.033GlyHis: 2.033 ± 0.527
4.575GlyIle: 4.575 ± 0.679
2.711GlyLys: 2.711 ± 0.522
5.591GlyLeu: 5.591 ± 0.52
1.355GlyMet: 1.355 ± 0.451
4.066GlyAsn: 4.066 ± 1.041
3.389GlyPro: 3.389 ± 0.923
1.186GlyGln: 1.186 ± 0.426
3.558GlyArg: 3.558 ± 0.653
6.269GlySer: 6.269 ± 1.581
3.219GlyThr: 3.219 ± 1.56
4.066GlyVal: 4.066 ± 1.386
0.169GlyTrp: 0.169 ± 0.158
2.711GlyTyr: 2.711 ± 0.722
0.0GlyXaa: 0.0 ± 0.0
His
1.017HisAla: 1.017 ± 0.489
0.339HisCys: 0.339 ± 0.193
1.017HisAsp: 1.017 ± 0.332
1.355HisGlu: 1.355 ± 0.358
1.017HisPhe: 1.017 ± 0.39
1.186HisGly: 1.186 ± 0.312
0.339HisHis: 0.339 ± 0.196
0.678HisIle: 0.678 ± 0.307
0.678HisLys: 0.678 ± 0.457
2.033HisLeu: 2.033 ± 0.604
0.508HisMet: 0.508 ± 0.343
1.525HisAsn: 1.525 ± 0.503
2.033HisPro: 2.033 ± 0.69
0.678HisGln: 0.678 ± 0.309
1.864HisArg: 1.864 ± 0.563
1.017HisSer: 1.017 ± 0.3
0.847HisThr: 0.847 ± 0.31
1.186HisVal: 1.186 ± 0.424
0.0HisTrp: 0.0 ± 0.0
0.678HisTyr: 0.678 ± 0.258
0.0HisXaa: 0.0 ± 0.0
Ile
3.728IleAla: 3.728 ± 0.949
1.525IleCys: 1.525 ± 0.33
3.558IleAsp: 3.558 ± 0.908
3.389IleGlu: 3.389 ± 0.573
2.033IlePhe: 2.033 ± 0.511
2.372IleGly: 2.372 ± 0.365
0.508IleHis: 0.508 ± 0.239
5.93IleIle: 5.93 ± 0.678
5.083IleLys: 5.083 ± 0.77
5.083IleLeu: 5.083 ± 0.867
1.694IleMet: 1.694 ± 0.698
5.252IleAsn: 5.252 ± 0.919
3.389IlePro: 3.389 ± 0.49
3.558IleGln: 3.558 ± 0.829
3.558IleArg: 3.558 ± 0.643
5.93IleSer: 5.93 ± 1.1
5.591IleThr: 5.591 ± 0.663
2.88IleVal: 2.88 ± 0.694
0.508IleTrp: 0.508 ± 0.239
2.88IleTyr: 2.88 ± 0.96
0.0IleXaa: 0.0 ± 0.0
Lys
3.219LysAla: 3.219 ± 0.614
0.847LysCys: 0.847 ± 0.292
2.711LysAsp: 2.711 ± 0.369
4.744LysGlu: 4.744 ± 0.534
1.525LysPhe: 1.525 ± 0.341
2.88LysGly: 2.88 ± 0.391
1.525LysHis: 1.525 ± 0.539
3.897LysIle: 3.897 ± 0.474
3.558LysLys: 3.558 ± 0.769
4.914LysLeu: 4.914 ± 1.614
2.033LysMet: 2.033 ± 0.649
3.219LysAsn: 3.219 ± 0.203
2.711LysPro: 2.711 ± 0.491
1.864LysGln: 1.864 ± 0.388
2.033LysArg: 2.033 ± 0.763
4.236LysSer: 4.236 ± 0.617
4.066LysThr: 4.066 ± 0.771
3.558LysVal: 3.558 ± 0.799
0.169LysTrp: 0.169 ± 0.205
2.372LysTyr: 2.372 ± 0.568
0.0LysXaa: 0.0 ± 0.0
Leu
5.591LeuAla: 5.591 ± 1.244
1.017LeuCys: 1.017 ± 0.405
6.269LeuAsp: 6.269 ± 0.826
4.405LeuGlu: 4.405 ± 1.543
2.542LeuPhe: 2.542 ± 0.99
6.438LeuGly: 6.438 ± 1.207
1.694LeuHis: 1.694 ± 0.39
6.269LeuIle: 6.269 ± 1.011
4.575LeuLys: 4.575 ± 0.899
8.133LeuLeu: 8.133 ± 1.154
2.372LeuMet: 2.372 ± 0.618
4.744LeuAsn: 4.744 ± 1.022
3.219LeuPro: 3.219 ± 0.342
4.405LeuGln: 4.405 ± 0.774
5.422LeuArg: 5.422 ± 0.978
7.116LeuSer: 7.116 ± 1.051
7.963LeuThr: 7.963 ± 0.818
4.914LeuVal: 4.914 ± 0.816
0.678LeuTrp: 0.678 ± 0.34
3.05LeuTyr: 3.05 ± 1.027
0.0LeuXaa: 0.0 ± 0.0
Met
1.186MetAla: 1.186 ± 0.476
0.508MetCys: 0.508 ± 0.238
1.355MetAsp: 1.355 ± 0.435
2.372MetGlu: 2.372 ± 0.732
0.678MetPhe: 0.678 ± 0.24
1.355MetGly: 1.355 ± 0.3
0.508MetHis: 0.508 ± 0.222
2.542MetIle: 2.542 ± 0.686
2.033MetLys: 2.033 ± 0.512
3.219MetLeu: 3.219 ± 0.701
0.847MetMet: 0.847 ± 0.463
0.847MetAsn: 0.847 ± 0.342
1.017MetPro: 1.017 ± 0.312
0.169MetGln: 0.169 ± 0.153
2.203MetArg: 2.203 ± 0.482
3.05MetSer: 3.05 ± 0.575
1.694MetThr: 1.694 ± 0.442
2.203MetVal: 2.203 ± 0.594
0.508MetTrp: 0.508 ± 0.245
1.355MetTyr: 1.355 ± 0.597
0.0MetXaa: 0.0 ± 0.0
Asn
3.05AsnAla: 3.05 ± 1.534
1.017AsnCys: 1.017 ± 0.515
3.219AsnAsp: 3.219 ± 0.653
2.711AsnGlu: 2.711 ± 0.312
1.355AsnPhe: 1.355 ± 0.325
2.88AsnGly: 2.88 ± 0.49
0.678AsnHis: 0.678 ± 0.245
3.728AsnIle: 3.728 ± 1.141
5.083AsnLys: 5.083 ± 0.945
5.252AsnLeu: 5.252 ± 1.153
1.186AsnMet: 1.186 ± 0.555
3.558AsnAsn: 3.558 ± 0.422
4.575AsnPro: 4.575 ± 0.956
3.05AsnGln: 3.05 ± 1.147
1.864AsnArg: 1.864 ± 0.476
4.236AsnSer: 4.236 ± 0.874
2.033AsnThr: 2.033 ± 0.52
2.711AsnVal: 2.711 ± 0.882
0.678AsnTrp: 0.678 ± 0.32
1.355AsnTyr: 1.355 ± 0.467
0.0AsnXaa: 0.0 ± 0.0
Pro
3.219ProAla: 3.219 ± 1.109
0.169ProCys: 0.169 ± 0.153
3.05ProAsp: 3.05 ± 1.27
3.389ProGlu: 3.389 ± 0.475
0.847ProPhe: 0.847 ± 0.354
3.389ProGly: 3.389 ± 0.973
0.678ProHis: 0.678 ± 0.258
2.711ProIle: 2.711 ± 0.554
4.575ProLys: 4.575 ± 1.158
3.728ProLeu: 3.728 ± 0.671
0.678ProMet: 0.678 ± 0.24
1.694ProAsn: 1.694 ± 0.506
2.203ProPro: 2.203 ± 0.689
1.694ProGln: 1.694 ± 0.459
2.88ProArg: 2.88 ± 0.601
4.236ProSer: 4.236 ± 0.849
3.219ProThr: 3.219 ± 0.771
3.05ProVal: 3.05 ± 0.469
0.169ProTrp: 0.169 ± 0.225
2.372ProTyr: 2.372 ± 0.722
0.0ProXaa: 0.0 ± 0.0
Gln
1.186GlnAla: 1.186 ± 0.401
0.678GlnCys: 0.678 ± 0.424
1.864GlnAsp: 1.864 ± 0.473
3.558GlnGlu: 3.558 ± 0.807
1.355GlnPhe: 1.355 ± 0.516
2.033GlnGly: 2.033 ± 0.438
0.0GlnHis: 0.0 ± 0.0
3.558GlnIle: 3.558 ± 1.131
2.711GlnLys: 2.711 ± 0.682
3.389GlnLeu: 3.389 ± 1.044
0.678GlnMet: 0.678 ± 0.229
2.033GlnAsn: 2.033 ± 0.497
1.355GlnPro: 1.355 ± 0.584
2.88GlnGln: 2.88 ± 0.979
2.033GlnArg: 2.033 ± 0.512
2.711GlnSer: 2.711 ± 0.689
1.525GlnThr: 1.525 ± 0.411
3.05GlnVal: 3.05 ± 0.434
0.169GlnTrp: 0.169 ± 0.114
0.847GlnTyr: 0.847 ± 0.349
0.0GlnXaa: 0.0 ± 0.0
Arg
4.236ArgAla: 4.236 ± 0.666
0.678ArgCys: 0.678 ± 0.263
2.372ArgAsp: 2.372 ± 0.551
3.219ArgGlu: 3.219 ± 0.928
1.355ArgPhe: 1.355 ± 0.287
3.728ArgGly: 3.728 ± 0.895
0.847ArgHis: 0.847 ± 0.329
2.711ArgIle: 2.711 ± 0.553
2.033ArgLys: 2.033 ± 0.556
4.914ArgLeu: 4.914 ± 0.677
1.864ArgMet: 1.864 ± 0.638
3.728ArgAsn: 3.728 ± 0.615
1.864ArgPro: 1.864 ± 0.626
2.033ArgGln: 2.033 ± 0.388
4.914ArgArg: 4.914 ± 1.083
4.405ArgSer: 4.405 ± 0.551
1.694ArgThr: 1.694 ± 0.466
3.897ArgVal: 3.897 ± 0.596
0.678ArgTrp: 0.678 ± 0.354
2.203ArgTyr: 2.203 ± 0.672
0.0ArgXaa: 0.0 ± 0.0
Ser
4.575SerAla: 4.575 ± 1.25
1.355SerCys: 1.355 ± 0.29
4.744SerAsp: 4.744 ± 1.616
4.744SerGlu: 4.744 ± 0.844
2.542SerPhe: 2.542 ± 0.448
4.575SerGly: 4.575 ± 0.991
1.017SerHis: 1.017 ± 0.686
4.575SerIle: 4.575 ± 1.255
2.203SerLys: 2.203 ± 0.737
7.794SerLeu: 7.794 ± 1.624
3.558SerMet: 3.558 ± 0.868
3.897SerAsn: 3.897 ± 0.746
2.542SerPro: 2.542 ± 0.563
2.711SerGln: 2.711 ± 0.467
5.591SerArg: 5.591 ± 0.998
6.438SerSer: 6.438 ± 1.615
6.269SerThr: 6.269 ± 1.162
5.761SerVal: 5.761 ± 1.092
1.355SerTrp: 1.355 ± 0.548
2.372SerTyr: 2.372 ± 0.687
0.0SerXaa: 0.0 ± 0.0
Thr
6.608ThrAla: 6.608 ± 1.435
1.017ThrCys: 1.017 ± 0.298
2.542ThrAsp: 2.542 ± 0.488
2.033ThrGlu: 2.033 ± 0.613
1.694ThrPhe: 1.694 ± 0.629
5.252ThrGly: 5.252 ± 0.942
1.186ThrHis: 1.186 ± 0.437
5.761ThrIle: 5.761 ± 0.81
3.389ThrLys: 3.389 ± 0.639
4.914ThrLeu: 4.914 ± 0.559
2.203ThrMet: 2.203 ± 0.363
2.033ThrAsn: 2.033 ± 0.558
2.711ThrPro: 2.711 ± 0.726
1.864ThrGln: 1.864 ± 0.559
3.05ThrArg: 3.05 ± 0.568
5.083ThrSer: 5.083 ± 1.013
5.761ThrThr: 5.761 ± 0.995
3.05ThrVal: 3.05 ± 0.722
0.678ThrTrp: 0.678 ± 0.279
2.88ThrTyr: 2.88 ± 0.541
0.0ThrXaa: 0.0 ± 0.0
Val
3.219ValAla: 3.219 ± 0.794
1.355ValCys: 1.355 ± 0.516
3.05ValAsp: 3.05 ± 0.689
3.219ValGlu: 3.219 ± 0.721
2.542ValPhe: 2.542 ± 0.499
4.914ValGly: 4.914 ± 0.854
1.694ValHis: 1.694 ± 0.458
2.542ValIle: 2.542 ± 0.664
3.389ValLys: 3.389 ± 0.592
5.761ValLeu: 5.761 ± 0.957
1.694ValMet: 1.694 ± 0.506
4.575ValAsn: 4.575 ± 0.792
3.558ValPro: 3.558 ± 0.962
2.033ValGln: 2.033 ± 0.446
2.033ValArg: 2.033 ± 0.703
4.405ValSer: 4.405 ± 0.99
4.066ValThr: 4.066 ± 0.805
4.236ValVal: 4.236 ± 0.956
0.847ValTrp: 0.847 ± 0.45
2.542ValTyr: 2.542 ± 0.908
0.0ValXaa: 0.0 ± 0.0
Trp
0.678TrpAla: 0.678 ± 0.279
0.508TrpCys: 0.508 ± 0.306
1.017TrpAsp: 1.017 ± 0.332
1.017TrpGlu: 1.017 ± 0.313
0.678TrpPhe: 0.678 ± 0.271
1.186TrpGly: 1.186 ± 0.643
0.169TrpHis: 0.169 ± 0.153
1.186TrpIle: 1.186 ± 0.332
0.678TrpLys: 0.678 ± 0.411
0.678TrpLeu: 0.678 ± 0.23
0.169TrpMet: 0.169 ± 0.153
0.339TrpAsn: 0.339 ± 0.229
0.339TrpPro: 0.339 ± 0.172
0.169TrpGln: 0.169 ± 0.153
0.169TrpArg: 0.169 ± 0.114
0.678TrpSer: 0.678 ± 0.359
0.169TrpThr: 0.169 ± 0.114
0.339TrpVal: 0.339 ± 0.2
0.169TrpTrp: 0.169 ± 0.114
0.339TrpTyr: 0.339 ± 0.229
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.017TyrAla: 1.017 ± 0.646
1.017TyrCys: 1.017 ± 0.287
1.355TyrAsp: 1.355 ± 0.373
2.033TyrGlu: 2.033 ± 0.494
2.033TyrPhe: 2.033 ± 0.678
2.711TyrGly: 2.711 ± 0.447
1.186TyrHis: 1.186 ± 0.439
2.542TyrIle: 2.542 ± 0.577
1.694TyrLys: 1.694 ± 0.513
4.744TyrLeu: 4.744 ± 1.009
1.694TyrMet: 1.694 ± 0.36
3.05TyrAsn: 3.05 ± 0.788
3.05TyrPro: 3.05 ± 0.561
1.525TyrGln: 1.525 ± 0.289
1.525TyrArg: 1.525 ± 0.292
2.711TyrSer: 2.711 ± 0.812
3.558TyrThr: 3.558 ± 0.99
1.017TyrVal: 1.017 ± 0.382
0.339TyrTrp: 0.339 ± 0.172
1.355TyrTyr: 1.355 ± 0.64
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (5903 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski