Amino acid dipepetide frequency for Daeseongdong virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.976AlaAla: 3.976 ± 0.802
1.325AlaCys: 1.325 ± 1.734
3.313AlaAsp: 3.313 ± 0.468
2.651AlaGlu: 2.651 ± 1.335
1.325AlaPhe: 1.325 ± 0.668
5.964AlaGly: 5.964 ± 0.598
0.663AlaHis: 0.663 ± 0.334
2.651AlaIle: 2.651 ± 1.066
5.302AlaLys: 5.302 ± 1.47
7.29AlaLeu: 7.29 ± 2.471
0.663AlaMet: 0.663 ± 0.334
2.651AlaAsn: 2.651 ± 1.335
5.302AlaPro: 5.302 ± 2.133
2.651AlaGln: 2.651 ± 0.134
5.964AlaArg: 5.964 ± 3.005
6.627AlaSer: 6.627 ± 3.867
2.651AlaThr: 2.651 ± 0.134
4.639AlaVal: 4.639 ± 1.136
1.325AlaTrp: 1.325 ± 0.668
1.988AlaTyr: 1.988 ± 0.199
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.663CysCys: 0.663 ± 0.334
0.0CysAsp: 0.0 ± 0.0
1.325CysGlu: 1.325 ± 0.668
0.0CysPhe: 0.0 ± 0.0
1.325CysGly: 1.325 ± 0.533
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.663CysLys: 0.663 ± 0.867
0.0CysLeu: 0.0 ± 0.0
0.663CysMet: 0.663 ± 0.334
0.0CysAsn: 0.0 ± 0.0
0.663CysPro: 0.663 ± 0.867
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.988CysSer: 1.988 ± 1.4
0.0CysThr: 0.0 ± 0.0
1.325CysVal: 1.325 ± 0.533
0.0CysTrp: 0.0 ± 0.0
1.325CysTyr: 1.325 ± 0.668
0.0CysXaa: 0.0 ± 0.0
Asp
3.313AspAla: 3.313 ± 0.733
0.0AspCys: 0.0 ± 0.0
4.639AspAsp: 4.639 ± 0.065
2.651AspGlu: 2.651 ± 0.134
1.988AspPhe: 1.988 ± 1.002
5.302AspGly: 5.302 ± 0.932
0.663AspHis: 0.663 ± 0.334
1.988AspIle: 1.988 ± 1.002
3.976AspLys: 3.976 ± 0.399
7.29AspLeu: 7.29 ± 0.07
0.663AspMet: 0.663 ± 0.334
0.663AspAsn: 0.663 ± 0.867
4.639AspPro: 4.639 ± 1.136
3.976AspGln: 3.976 ± 2.003
3.976AspArg: 3.976 ± 2.003
1.988AspSer: 1.988 ± 0.199
3.313AspThr: 3.313 ± 0.733
3.976AspVal: 3.976 ± 0.399
1.325AspTrp: 1.325 ± 0.533
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.964GluAla: 5.964 ± 1.804
0.663GluCys: 0.663 ± 0.334
3.976GluAsp: 3.976 ± 1.6
5.302GluGlu: 5.302 ± 0.269
1.988GluPhe: 1.988 ± 1.002
4.639GluGly: 4.639 ± 1.266
1.988GluHis: 1.988 ± 0.199
3.313GluIle: 3.313 ± 1.669
1.988GluLys: 1.988 ± 0.199
3.976GluLeu: 3.976 ± 0.399
1.325GluMet: 1.325 ± 0.533
1.988GluAsn: 1.988 ± 0.199
2.651GluPro: 2.651 ± 0.134
1.988GluGln: 1.988 ± 1.002
5.964GluArg: 5.964 ± 3.005
2.651GluSer: 2.651 ± 1.335
2.651GluThr: 2.651 ± 0.134
9.278GluVal: 9.278 ± 3.473
0.663GluTrp: 0.663 ± 0.334
1.325GluTyr: 1.325 ± 0.533
0.0GluXaa: 0.0 ± 0.0
Phe
0.663PheAla: 0.663 ± 0.334
0.663PheCys: 0.663 ± 0.334
0.663PheAsp: 0.663 ± 0.334
3.313PheGlu: 3.313 ± 0.468
1.325PhePhe: 1.325 ± 0.533
1.988PheGly: 1.988 ± 1.002
0.663PheHis: 0.663 ± 0.867
0.0PheIle: 0.0 ± 0.0
2.651PheLys: 2.651 ± 0.134
3.313PheLeu: 3.313 ± 1.669
0.663PheMet: 0.663 ± 0.334
0.663PheAsn: 0.663 ± 0.334
2.651PhePro: 2.651 ± 1.335
1.325PheGln: 1.325 ± 0.533
1.325PheArg: 1.325 ± 1.734
3.313PheSer: 3.313 ± 3.134
2.651PheThr: 2.651 ± 0.134
2.651PheVal: 2.651 ± 1.066
1.325PheTrp: 1.325 ± 0.533
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.651GlyAla: 2.651 ± 1.335
0.0GlyCys: 0.0 ± 0.0
1.988GlyAsp: 1.988 ± 0.199
3.976GlyGlu: 3.976 ± 0.802
3.976GlyPhe: 3.976 ± 2.003
7.29GlyGly: 7.29 ± 1.131
1.325GlyHis: 1.325 ± 0.668
4.639GlyIle: 4.639 ± 1.136
3.976GlyLys: 3.976 ± 0.399
7.952GlyLeu: 7.952 ± 1.604
0.663GlyMet: 0.663 ± 0.334
1.988GlyAsn: 1.988 ± 2.601
3.313GlyPro: 3.313 ± 1.669
0.663GlyGln: 0.663 ± 0.867
1.325GlyArg: 1.325 ± 0.668
6.627GlySer: 6.627 ± 5.068
6.627GlyThr: 6.627 ± 1.465
4.639GlyVal: 4.639 ± 1.136
1.325GlyTrp: 1.325 ± 0.668
1.325GlyTyr: 1.325 ± 1.734
0.0GlyXaa: 0.0 ± 0.0
His
0.663HisAla: 0.663 ± 0.867
0.0HisCys: 0.0 ± 0.0
0.663HisAsp: 0.663 ± 0.867
0.0HisGlu: 0.0 ± 0.0
2.651HisPhe: 2.651 ± 2.267
1.325HisGly: 1.325 ± 0.668
0.0HisHis: 0.0 ± 0.0
1.988HisIle: 1.988 ± 0.199
1.325HisLys: 1.325 ± 0.533
3.313HisLeu: 3.313 ± 0.733
0.663HisMet: 0.663 ± 0.334
1.325HisAsn: 1.325 ± 0.668
1.988HisPro: 1.988 ± 0.199
0.0HisGln: 0.0 ± 0.0
0.663HisArg: 0.663 ± 0.334
0.663HisSer: 0.663 ± 0.867
0.663HisThr: 0.663 ± 0.334
1.988HisVal: 1.988 ± 0.199
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.302IleAla: 5.302 ± 2.671
0.663IleCys: 0.663 ± 0.867
1.325IleAsp: 1.325 ± 0.668
1.988IleGlu: 1.988 ± 1.002
2.651IlePhe: 2.651 ± 1.335
0.663IleGly: 0.663 ± 0.867
1.988IleHis: 1.988 ± 0.199
1.325IleIle: 1.325 ± 0.533
3.976IleLys: 3.976 ± 0.399
3.313IleLeu: 3.313 ± 1.669
0.663IleMet: 0.663 ± 0.867
1.988IleAsn: 1.988 ± 0.199
6.627IlePro: 6.627 ± 1.465
1.988IleGln: 1.988 ± 0.199
2.651IleArg: 2.651 ± 1.066
1.325IleSer: 1.325 ± 0.668
3.313IleThr: 3.313 ± 1.933
4.639IleVal: 4.639 ± 1.136
0.0IleTrp: 0.0 ± 0.0
0.663IleTyr: 0.663 ± 0.334
0.0IleXaa: 0.0 ± 0.0
Lys
3.313LysAla: 3.313 ± 0.733
0.0LysCys: 0.0 ± 0.0
3.313LysAsp: 3.313 ± 1.669
1.988LysGlu: 1.988 ± 1.002
1.325LysPhe: 1.325 ± 0.533
1.325LysGly: 1.325 ± 0.668
0.0LysHis: 0.0 ± 0.0
1.325LysIle: 1.325 ± 0.668
3.976LysLys: 3.976 ± 2.801
3.976LysLeu: 3.976 ± 0.399
3.976LysMet: 3.976 ± 0.802
4.639LysAsn: 4.639 ± 0.065
1.325LysPro: 1.325 ± 0.668
2.651LysGln: 2.651 ± 0.134
5.964LysArg: 5.964 ± 1.804
5.964LysSer: 5.964 ± 0.598
5.302LysThr: 5.302 ± 0.269
8.615LysVal: 8.615 ± 0.737
1.325LysTrp: 1.325 ± 0.533
0.663LysTyr: 0.663 ± 0.867
0.0LysXaa: 0.0 ± 0.0
Leu
7.952LeuAla: 7.952 ± 0.403
1.988LeuCys: 1.988 ± 0.199
3.976LeuAsp: 3.976 ± 2.003
8.615LeuGlu: 8.615 ± 0.464
1.325LeuPhe: 1.325 ± 0.668
2.651LeuGly: 2.651 ± 1.335
0.663LeuHis: 0.663 ± 0.334
3.976LeuIle: 3.976 ± 1.6
5.964LeuLys: 5.964 ± 0.598
2.651LeuLeu: 2.651 ± 1.335
3.313LeuMet: 3.313 ± 0.24
3.976LeuAsn: 3.976 ± 0.802
2.651LeuPro: 2.651 ± 1.335
2.651LeuGln: 2.651 ± 0.134
2.651LeuArg: 2.651 ± 1.335
7.29LeuSer: 7.29 ± 2.332
3.976LeuThr: 3.976 ± 0.802
4.639LeuVal: 4.639 ± 1.136
1.325LeuTrp: 1.325 ± 0.668
5.964LeuTyr: 5.964 ± 1.804
0.0LeuXaa: 0.0 ± 0.0
Met
1.325MetAla: 1.325 ± 0.668
0.0MetCys: 0.0 ± 0.0
1.988MetAsp: 1.988 ± 1.002
1.325MetGlu: 1.325 ± 0.668
0.663MetPhe: 0.663 ± 0.867
1.988MetGly: 1.988 ± 0.199
0.663MetHis: 0.663 ± 0.867
1.325MetIle: 1.325 ± 0.668
0.663MetLys: 0.663 ± 0.334
1.325MetLeu: 1.325 ± 0.668
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.313MetPro: 3.313 ± 0.733
0.663MetGln: 0.663 ± 0.334
1.325MetArg: 1.325 ± 0.668
2.651MetSer: 2.651 ± 0.134
1.988MetThr: 1.988 ± 0.199
1.988MetVal: 1.988 ± 0.199
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.976AsnAla: 3.976 ± 0.399
0.0AsnCys: 0.0 ± 0.0
1.988AsnAsp: 1.988 ± 1.002
0.663AsnGlu: 0.663 ± 0.867
0.663AsnPhe: 0.663 ± 0.867
4.639AsnGly: 4.639 ± 0.065
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
2.651AsnLys: 2.651 ± 1.335
1.988AsnLeu: 1.988 ± 1.4
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
5.964AsnPro: 5.964 ± 1.804
1.988AsnGln: 1.988 ± 0.199
1.988AsnArg: 1.988 ± 1.002
2.651AsnSer: 2.651 ± 2.267
1.325AsnThr: 1.325 ± 0.668
2.651AsnVal: 2.651 ± 0.134
1.325AsnTrp: 1.325 ± 0.668
0.663AsnTyr: 0.663 ± 0.334
0.0AsnXaa: 0.0 ± 0.0
Pro
5.964ProAla: 5.964 ± 0.603
0.0ProCys: 0.0 ± 0.0
4.639ProAsp: 4.639 ± 1.136
5.964ProGlu: 5.964 ± 0.603
0.663ProPhe: 0.663 ± 0.334
3.976ProGly: 3.976 ± 1.6
1.988ProHis: 1.988 ± 0.199
5.302ProIle: 5.302 ± 0.269
2.651ProLys: 2.651 ± 1.335
4.639ProLeu: 4.639 ± 1.136
0.663ProMet: 0.663 ± 0.282
2.651ProAsn: 2.651 ± 0.134
3.976ProPro: 3.976 ± 2.003
1.988ProGln: 1.988 ± 1.4
5.302ProArg: 5.302 ± 3.334
3.313ProSer: 3.313 ± 4.335
5.964ProThr: 5.964 ± 0.603
2.651ProVal: 2.651 ± 1.335
0.663ProTrp: 0.663 ± 0.334
1.988ProTyr: 1.988 ± 1.002
0.0ProXaa: 0.0 ± 0.0
Gln
1.325GlnAla: 1.325 ± 0.533
0.0GlnCys: 0.0 ± 0.0
3.976GlnAsp: 3.976 ± 0.802
2.651GlnGlu: 2.651 ± 0.134
0.663GlnPhe: 0.663 ± 0.867
3.313GlnGly: 3.313 ± 0.468
0.663GlnHis: 0.663 ± 0.867
3.313GlnIle: 3.313 ± 1.669
1.988GlnLys: 1.988 ± 1.002
1.988GlnLeu: 1.988 ± 1.002
1.988GlnMet: 1.988 ± 0.199
1.325GlnAsn: 1.325 ± 0.668
1.325GlnPro: 1.325 ± 0.533
2.651GlnGln: 2.651 ± 1.066
3.976GlnArg: 3.976 ± 0.399
1.988GlnSer: 1.988 ± 0.199
1.988GlnThr: 1.988 ± 0.199
2.651GlnVal: 2.651 ± 1.066
0.663GlnTrp: 0.663 ± 0.334
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.651ArgAla: 2.651 ± 0.134
0.663ArgCys: 0.663 ± 0.334
1.988ArgAsp: 1.988 ± 0.199
3.976ArgGlu: 3.976 ± 0.399
0.663ArgPhe: 0.663 ± 0.867
3.976ArgGly: 3.976 ± 2.003
1.988ArgHis: 1.988 ± 0.199
1.325ArgIle: 1.325 ± 0.533
5.302ArgLys: 5.302 ± 0.269
6.627ArgLeu: 6.627 ± 2.138
2.651ArgMet: 2.651 ± 0.134
1.325ArgAsn: 1.325 ± 0.533
2.651ArgPro: 2.651 ± 1.066
3.976ArgGln: 3.976 ± 2.003
6.627ArgArg: 6.627 ± 1.465
7.952ArgSer: 7.952 ± 0.403
3.976ArgThr: 3.976 ± 2.003
5.302ArgVal: 5.302 ± 0.269
0.663ArgTrp: 0.663 ± 0.867
1.988ArgTyr: 1.988 ± 1.002
0.0ArgXaa: 0.0 ± 0.0
Ser
4.639SerAla: 4.639 ± 0.065
1.325SerCys: 1.325 ± 0.533
6.627SerAsp: 6.627 ± 3.867
8.615SerGlu: 8.615 ± 1.938
1.988SerPhe: 1.988 ± 1.4
6.627SerGly: 6.627 ± 1.465
1.988SerHis: 1.988 ± 0.199
5.964SerIle: 5.964 ± 3.0
1.988SerLys: 1.988 ± 1.002
6.627SerLeu: 6.627 ± 3.867
1.325SerMet: 1.325 ± 0.533
3.313SerAsn: 3.313 ± 0.468
4.639SerPro: 4.639 ± 4.869
1.988SerGln: 1.988 ± 1.4
5.302SerArg: 5.302 ± 2.133
9.94SerSer: 9.94 ± 4.6
5.964SerThr: 5.964 ± 4.201
2.651SerVal: 2.651 ± 0.134
0.663SerTrp: 0.663 ± 0.334
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.639ThrAla: 4.639 ± 0.065
0.0ThrCys: 0.0 ± 0.0
6.627ThrAsp: 6.627 ± 0.264
1.325ThrGlu: 1.325 ± 0.668
1.988ThrPhe: 1.988 ± 1.4
2.651ThrGly: 2.651 ± 1.066
0.663ThrHis: 0.663 ± 0.867
3.976ThrIle: 3.976 ± 0.399
2.651ThrLys: 2.651 ± 1.066
5.302ThrLeu: 5.302 ± 1.47
0.663ThrMet: 0.663 ± 0.334
0.663ThrAsn: 0.663 ± 0.334
2.651ThrPro: 2.651 ± 1.335
3.976ThrGln: 3.976 ± 2.003
5.302ThrArg: 5.302 ± 0.269
7.29ThrSer: 7.29 ± 2.332
5.302ThrThr: 5.302 ± 0.269
7.29ThrVal: 7.29 ± 3.533
1.988ThrTrp: 1.988 ± 0.199
1.988ThrTyr: 1.988 ± 1.4
0.0ThrXaa: 0.0 ± 0.0
Val
8.615ValAla: 8.615 ± 1.664
1.988ValCys: 1.988 ± 0.199
3.313ValAsp: 3.313 ± 0.468
5.964ValGlu: 5.964 ± 0.603
5.302ValPhe: 5.302 ± 1.47
3.976ValGly: 3.976 ± 0.802
3.976ValHis: 3.976 ± 1.6
1.325ValIle: 1.325 ± 0.668
5.302ValLys: 5.302 ± 2.671
5.964ValLeu: 5.964 ± 0.598
0.663ValMet: 0.663 ± 0.334
3.313ValAsn: 3.313 ± 0.733
6.627ValPro: 6.627 ± 0.264
0.0ValGln: 0.0 ± 0.0
1.988ValArg: 1.988 ± 0.199
5.964ValSer: 5.964 ± 0.598
5.302ValThr: 5.302 ± 0.269
4.639ValVal: 4.639 ± 0.065
1.988ValTrp: 1.988 ± 1.002
2.651ValTyr: 2.651 ± 1.335
0.0ValXaa: 0.0 ± 0.0
Trp
0.663TrpAla: 0.663 ± 0.334
0.0TrpCys: 0.0 ± 0.0
1.325TrpAsp: 1.325 ± 0.668
1.325TrpGlu: 1.325 ± 0.668
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.988TrpIle: 1.988 ± 0.199
1.325TrpLys: 1.325 ± 0.668
0.0TrpLeu: 0.0 ± 0.0
1.325TrpMet: 1.325 ± 0.668
1.988TrpAsn: 1.988 ± 1.002
0.663TrpPro: 0.663 ± 0.334
1.988TrpGln: 1.988 ± 0.199
2.651TrpArg: 2.651 ± 0.134
0.0TrpSer: 0.0 ± 0.0
0.663TrpThr: 0.663 ± 0.867
0.663TrpVal: 0.663 ± 0.334
0.0TrpTrp: 0.0 ± 0.0
0.663TrpTyr: 0.663 ± 0.867
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.325TyrAla: 1.325 ± 0.668
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
0.663TyrGlu: 0.663 ± 0.334
0.663TyrPhe: 0.663 ± 0.867
2.651TyrGly: 2.651 ± 1.335
0.0TyrHis: 0.0 ± 0.0
1.325TyrIle: 1.325 ± 0.668
2.651TyrLys: 2.651 ± 1.066
1.325TyrLeu: 1.325 ± 0.668
0.0TyrMet: 0.0 ± 0.0
0.663TyrAsn: 0.663 ± 0.334
1.325TyrPro: 1.325 ± 0.668
1.325TyrGln: 1.325 ± 1.734
1.325TyrArg: 1.325 ± 0.668
1.988TyrSer: 1.988 ± 1.002
3.313TyrThr: 3.313 ± 1.933
1.988TyrVal: 1.988 ± 0.199
0.663TyrTrp: 0.663 ± 0.334
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1510 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski