Amino acid dipepetide frequency for Gordonia effusa NBRC 100432

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.457AlaAla: 18.457 ± 0.152
0.821AlaCys: 0.821 ± 0.024
8.76AlaAsp: 8.76 ± 0.099
6.763AlaGlu: 6.763 ± 0.081
3.341AlaPhe: 3.341 ± 0.049
11.025AlaGly: 11.025 ± 0.108
2.457AlaHis: 2.457 ± 0.043
6.227AlaIle: 6.227 ± 0.073
3.418AlaLys: 3.418 ± 0.058
12.226AlaLeu: 12.226 ± 0.119
2.732AlaMet: 2.732 ± 0.047
2.829AlaAsn: 2.829 ± 0.048
5.81AlaPro: 5.81 ± 0.075
4.402AlaGln: 4.402 ± 0.059
8.07AlaArg: 8.07 ± 0.084
6.825AlaSer: 6.825 ± 0.076
7.701AlaThr: 7.701 ± 0.074
10.813AlaVal: 10.813 ± 0.101
1.449AlaTrp: 1.449 ± 0.035
2.332AlaTyr: 2.332 ± 0.045
0.0AlaXaa: 0.0 ± 0.0
Cys
0.986CysAla: 0.986 ± 0.03
0.07CysCys: 0.07 ± 0.007
0.472CysAsp: 0.472 ± 0.021
0.337CysGlu: 0.337 ± 0.014
0.193CysPhe: 0.193 ± 0.011
0.82CysGly: 0.82 ± 0.026
0.158CysHis: 0.158 ± 0.011
0.256CysIle: 0.256 ± 0.013
0.143CysLys: 0.143 ± 0.01
0.548CysLeu: 0.548 ± 0.02
0.117CysMet: 0.117 ± 0.01
0.159CysAsn: 0.159 ± 0.012
0.358CysPro: 0.358 ± 0.017
0.189CysGln: 0.189 ± 0.011
0.444CysArg: 0.444 ± 0.017
0.427CysSer: 0.427 ± 0.017
0.437CysThr: 0.437 ± 0.019
0.577CysVal: 0.577 ± 0.02
0.109CysTrp: 0.109 ± 0.009
0.16CysTyr: 0.16 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
8.114AspAla: 8.114 ± 0.084
0.37AspCys: 0.37 ± 0.015
5.109AspAsp: 5.109 ± 0.071
4.083AspGlu: 4.083 ± 0.066
1.926AspPhe: 1.926 ± 0.041
5.829AspGly: 5.829 ± 0.067
1.442AspHis: 1.442 ± 0.034
2.907AspIle: 2.907 ± 0.049
1.436AspLys: 1.436 ± 0.037
6.237AspLeu: 6.237 ± 0.072
0.996AspMet: 0.996 ± 0.025
1.454AspAsn: 1.454 ± 0.036
3.967AspPro: 3.967 ± 0.052
1.83AspGln: 1.83 ± 0.036
4.316AspArg: 4.316 ± 0.06
3.432AspSer: 3.432 ± 0.047
3.261AspThr: 3.261 ± 0.059
5.741AspVal: 5.741 ± 0.078
0.979AspTrp: 0.979 ± 0.026
1.485AspTyr: 1.485 ± 0.034
0.0AspXaa: 0.0 ± 0.0
Glu
5.278GluAla: 5.278 ± 0.075
0.339GluCys: 0.339 ± 0.016
2.062GluAsp: 2.062 ± 0.045
2.214GluGlu: 2.214 ± 0.046
1.934GluPhe: 1.934 ± 0.037
2.976GluGly: 2.976 ± 0.046
1.318GluHis: 1.318 ± 0.031
2.753GluIle: 2.753 ± 0.051
1.43GluLys: 1.43 ± 0.032
6.456GluLeu: 6.456 ± 0.09
1.097GluMet: 1.097 ± 0.028
1.223GluAsn: 1.223 ± 0.031
2.637GluPro: 2.637 ± 0.053
2.106GluGln: 2.106 ± 0.046
4.095GluArg: 4.095 ± 0.057
3.157GluSer: 3.157 ± 0.054
2.684GluThr: 2.684 ± 0.054
4.267GluVal: 4.267 ± 0.058
0.774GluTrp: 0.774 ± 0.023
1.225GluTyr: 1.225 ± 0.03
0.0GluXaa: 0.0 ± 0.0
Phe
4.229PheAla: 4.229 ± 0.062
0.264PheCys: 0.264 ± 0.016
2.635PheAsp: 2.635 ± 0.053
1.495PheGlu: 1.495 ± 0.032
0.975PhePhe: 0.975 ± 0.028
3.647PheGly: 3.647 ± 0.063
0.613PheHis: 0.613 ± 0.023
1.236PheIle: 1.236 ± 0.031
0.495PheLys: 0.495 ± 0.023
2.441PheLeu: 2.441 ± 0.04
0.483PheMet: 0.483 ± 0.016
0.738PheAsn: 0.738 ± 0.025
1.333PhePro: 1.333 ± 0.031
0.606PheGln: 0.606 ± 0.02
1.676PheArg: 1.676 ± 0.035
1.83PheSer: 1.83 ± 0.031
2.053PheThr: 2.053 ± 0.039
2.717PheVal: 2.717 ± 0.042
0.415PheTrp: 0.415 ± 0.02
0.731PheTyr: 0.731 ± 0.023
0.0PheXaa: 0.0 ± 0.0
Gly
9.827GlyAla: 9.827 ± 0.106
0.716GlyCys: 0.716 ± 0.022
5.076GlyAsp: 5.076 ± 0.059
4.34GlyGlu: 4.34 ± 0.066
3.011GlyPhe: 3.011 ± 0.044
7.326GlyGly: 7.326 ± 0.085
1.888GlyHis: 1.888 ± 0.041
4.574GlyIle: 4.574 ± 0.069
2.687GlyLys: 2.687 ± 0.048
8.138GlyLeu: 8.138 ± 0.086
2.004GlyMet: 2.004 ± 0.042
2.07GlyAsn: 2.07 ± 0.041
4.095GlyPro: 4.095 ± 0.057
2.81GlyGln: 2.81 ± 0.052
5.817GlyArg: 5.817 ± 0.069
5.435GlySer: 5.435 ± 0.064
5.244GlyThr: 5.244 ± 0.06
7.491GlyVal: 7.491 ± 0.075
1.513GlyTrp: 1.513 ± 0.034
2.357GlyTyr: 2.357 ± 0.044
0.0GlyXaa: 0.0 ± 0.0
His
2.174HisAla: 2.174 ± 0.046
0.177HisCys: 0.177 ± 0.012
1.286HisAsp: 1.286 ± 0.036
0.961HisGlu: 0.961 ± 0.028
0.665HisPhe: 0.665 ± 0.022
1.834HisGly: 1.834 ± 0.036
0.606HisHis: 0.606 ± 0.024
0.92HisIle: 0.92 ± 0.026
0.404HisLys: 0.404 ± 0.016
2.051HisLeu: 2.051 ± 0.039
0.352HisMet: 0.352 ± 0.016
0.547HisAsn: 0.547 ± 0.017
1.414HisPro: 1.414 ± 0.032
0.613HisGln: 0.613 ± 0.019
1.746HisArg: 1.746 ± 0.041
1.203HisSer: 1.203 ± 0.031
1.165HisThr: 1.165 ± 0.031
1.525HisVal: 1.525 ± 0.033
0.318HisTrp: 0.318 ± 0.016
0.524HisTyr: 0.524 ± 0.02
0.0HisXaa: 0.0 ± 0.0
Ile
7.342IleAla: 7.342 ± 0.073
0.393IleCys: 0.393 ± 0.017
3.991IleAsp: 3.991 ± 0.058
2.751IleGlu: 2.751 ± 0.046
1.305IlePhe: 1.305 ± 0.033
4.998IleGly: 4.998 ± 0.069
0.854IleHis: 0.854 ± 0.025
1.966IleIle: 1.966 ± 0.042
1.023IleLys: 1.023 ± 0.028
3.654IleLeu: 3.654 ± 0.06
0.627IleMet: 0.627 ± 0.02
1.278IleAsn: 1.278 ± 0.031
2.604IlePro: 2.604 ± 0.039
0.903IleGln: 0.903 ± 0.024
2.899IleArg: 2.899 ± 0.051
2.965IleSer: 2.965 ± 0.05
3.151IleThr: 3.151 ± 0.05
4.493IleVal: 4.493 ± 0.068
0.525IleTrp: 0.525 ± 0.02
0.873IleTyr: 0.873 ± 0.025
0.0IleXaa: 0.0 ± 0.0
Lys
2.899LysAla: 2.899 ± 0.054
0.132LysCys: 0.132 ± 0.011
1.111LysAsp: 1.111 ± 0.033
0.998LysGlu: 0.998 ± 0.028
0.742LysPhe: 0.742 ± 0.024
1.725LysGly: 1.725 ± 0.039
0.513LysHis: 0.513 ± 0.02
1.279LysIle: 1.279 ± 0.034
0.873LysLys: 0.873 ± 0.037
2.472LysLeu: 2.472 ± 0.045
0.566LysMet: 0.566 ± 0.021
0.612LysAsn: 0.612 ± 0.02
1.544LysPro: 1.544 ± 0.044
0.823LysGln: 0.823 ± 0.029
1.763LysArg: 1.763 ± 0.037
1.618LysSer: 1.618 ± 0.039
1.671LysThr: 1.671 ± 0.04
2.35LysVal: 2.35 ± 0.044
0.364LysTrp: 0.364 ± 0.017
0.59LysTyr: 0.59 ± 0.023
0.0LysXaa: 0.0 ± 0.0
Leu
13.348LeuAla: 13.348 ± 0.122
0.739LeuCys: 0.739 ± 0.024
6.5LeuAsp: 6.5 ± 0.084
3.807LeuGlu: 3.807 ± 0.054
2.687LeuPhe: 2.687 ± 0.052
8.355LeuGly: 8.355 ± 0.077
1.801LeuHis: 1.801 ± 0.038
4.74LeuIle: 4.74 ± 0.068
1.916LeuLys: 1.916 ± 0.04
8.999LeuLeu: 8.999 ± 0.104
1.727LeuMet: 1.727 ± 0.036
2.23LeuAsn: 2.23 ± 0.045
5.398LeuPro: 5.398 ± 0.065
2.066LeuGln: 2.066 ± 0.038
7.247LeuArg: 7.247 ± 0.074
6.23LeuSer: 6.23 ± 0.068
6.706LeuThr: 6.706 ± 0.074
8.214LeuVal: 8.214 ± 0.083
1.195LeuTrp: 1.195 ± 0.033
1.633LeuTyr: 1.633 ± 0.039
0.0LeuXaa: 0.0 ± 0.0
Met
2.347MetAla: 2.347 ± 0.04
0.159MetCys: 0.159 ± 0.011
0.83MetAsp: 0.83 ± 0.026
0.634MetGlu: 0.634 ± 0.024
0.671MetPhe: 0.671 ± 0.022
1.36MetGly: 1.36 ± 0.032
0.378MetHis: 0.378 ± 0.017
1.043MetIle: 1.043 ± 0.027
0.502MetLys: 0.502 ± 0.02
1.93MetLeu: 1.93 ± 0.04
0.438MetMet: 0.438 ± 0.019
0.526MetAsn: 0.526 ± 0.018
1.171MetPro: 1.171 ± 0.029
0.436MetGln: 0.436 ± 0.017
1.456MetArg: 1.456 ± 0.036
1.75MetSer: 1.75 ± 0.037
1.865MetThr: 1.865 ± 0.037
1.624MetVal: 1.624 ± 0.04
0.29MetTrp: 0.29 ± 0.016
0.338MetTyr: 0.338 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
2.807AsnAla: 2.807 ± 0.042
0.169AsnCys: 0.169 ± 0.01
1.395AsnAsp: 1.395 ± 0.032
1.107AsnGlu: 1.107 ± 0.033
0.694AsnPhe: 0.694 ± 0.022
2.268AsnGly: 2.268 ± 0.046
0.481AsnHis: 0.481 ± 0.021
1.09AsnIle: 1.09 ± 0.029
0.648AsnLys: 0.648 ± 0.021
2.233AsnLeu: 2.233 ± 0.041
0.42AsnMet: 0.42 ± 0.018
0.696AsnAsn: 0.696 ± 0.026
1.815AsnPro: 1.815 ± 0.037
0.722AsnGln: 0.722 ± 0.025
1.676AsnArg: 1.676 ± 0.036
1.565AsnSer: 1.565 ± 0.031
1.515AsnThr: 1.515 ± 0.036
1.931AsnVal: 1.931 ± 0.031
0.398AsnTrp: 0.398 ± 0.016
0.618AsnTyr: 0.618 ± 0.023
0.0AsnXaa: 0.0 ± 0.0
Pro
6.506ProAla: 6.506 ± 0.077
0.222ProCys: 0.222 ± 0.013
4.163ProAsp: 4.163 ± 0.062
3.144ProGlu: 3.144 ± 0.051
1.569ProPhe: 1.569 ± 0.03
4.89ProGly: 4.89 ± 0.063
1.066ProHis: 1.066 ± 0.029
2.461ProIle: 2.461 ± 0.047
1.487ProLys: 1.487 ± 0.039
4.576ProLeu: 4.576 ± 0.059
1.05ProMet: 1.05 ± 0.03
1.495ProAsn: 1.495 ± 0.037
2.761ProPro: 2.761 ± 0.058
1.709ProGln: 1.709 ± 0.038
3.193ProArg: 3.193 ± 0.047
3.395ProSer: 3.395 ± 0.046
3.935ProThr: 3.935 ± 0.066
4.451ProVal: 4.451 ± 0.057
0.742ProTrp: 0.742 ± 0.026
1.099ProTyr: 1.099 ± 0.026
0.0ProXaa: 0.0 ± 0.0
Gln
3.393GlnAla: 3.393 ± 0.048
0.204GlnCys: 0.204 ± 0.013
1.012GlnAsp: 1.012 ± 0.027
1.042GlnGlu: 1.042 ± 0.027
0.94GlnPhe: 0.94 ± 0.026
1.88GlnGly: 1.88 ± 0.043
0.627GlnHis: 0.627 ± 0.022
1.709GlnIle: 1.709 ± 0.034
0.651GlnLys: 0.651 ± 0.022
3.373GlnLeu: 3.373 ± 0.057
0.707GlnMet: 0.707 ± 0.024
0.631GlnAsn: 0.631 ± 0.025
1.742GlnPro: 1.742 ± 0.045
1.293GlnGln: 1.293 ± 0.045
2.6GlnArg: 2.6 ± 0.042
1.775GlnSer: 1.775 ± 0.037
1.721GlnThr: 1.721 ± 0.035
2.644GlnVal: 2.644 ± 0.04
0.557GlnTrp: 0.557 ± 0.019
0.681GlnTyr: 0.681 ± 0.024
0.0GlnXaa: 0.0 ± 0.0
Arg
7.778ArgAla: 7.778 ± 0.087
0.445ArgCys: 0.445 ± 0.017
4.21ArgAsp: 4.21 ± 0.062
3.761ArgGlu: 3.761 ± 0.065
2.275ArgPhe: 2.275 ± 0.043
5.027ArgGly: 5.027 ± 0.066
1.577ArgHis: 1.577 ± 0.032
3.605ArgIle: 3.605 ± 0.054
1.925ArgLys: 1.925 ± 0.041
6.772ArgLeu: 6.772 ± 0.083
1.645ArgMet: 1.645 ± 0.032
1.778ArgAsn: 1.778 ± 0.042
3.532ArgPro: 3.532 ± 0.054
2.129ArgGln: 2.129 ± 0.04
6.095ArgArg: 6.095 ± 0.09
4.194ArgSer: 4.194 ± 0.051
4.227ArgThr: 4.227 ± 0.058
5.534ArgVal: 5.534 ± 0.062
1.265ArgTrp: 1.265 ± 0.029
1.781ArgTyr: 1.781 ± 0.037
0.0ArgXaa: 0.0 ± 0.0
Ser
7.732SerAla: 7.732 ± 0.079
0.36SerCys: 0.36 ± 0.017
3.943SerAsp: 3.943 ± 0.056
2.949SerGlu: 2.949 ± 0.05
1.833SerPhe: 1.833 ± 0.035
6.209SerGly: 6.209 ± 0.073
1.113SerHis: 1.113 ± 0.033
2.819SerIle: 2.819 ± 0.045
1.544SerLys: 1.544 ± 0.036
5.223SerLeu: 5.223 ± 0.062
1.41SerMet: 1.41 ± 0.027
1.44SerAsn: 1.44 ± 0.031
3.337SerPro: 3.337 ± 0.049
1.676SerGln: 1.676 ± 0.036
3.908SerArg: 3.908 ± 0.056
3.974SerSer: 3.974 ± 0.062
4.326SerThr: 4.326 ± 0.052
5.37SerVal: 5.37 ± 0.074
0.946SerTrp: 0.946 ± 0.027
1.309SerTyr: 1.309 ± 0.027
0.0SerXaa: 0.0 ± 0.0
Thr
7.85ThrAla: 7.85 ± 0.074
0.396ThrCys: 0.396 ± 0.015
4.061ThrAsp: 4.061 ± 0.052
3.362ThrGlu: 3.362 ± 0.046
1.912ThrPhe: 1.912 ± 0.035
5.806ThrGly: 5.806 ± 0.067
1.214ThrHis: 1.214 ± 0.031
3.04ThrIle: 3.04 ± 0.049
1.553ThrLys: 1.553 ± 0.041
5.889ThrLeu: 5.889 ± 0.064
1.209ThrMet: 1.209 ± 0.028
1.412ThrAsn: 1.412 ± 0.033
4.037ThrPro: 4.037 ± 0.061
1.682ThrGln: 1.682 ± 0.036
3.788ThrArg: 3.788 ± 0.046
4.129ThrSer: 4.129 ± 0.055
4.423ThrThr: 4.423 ± 0.065
5.958ThrVal: 5.958 ± 0.065
0.858ThrTrp: 0.858 ± 0.024
1.409ThrTyr: 1.409 ± 0.03
0.0ThrXaa: 0.0 ± 0.0
Val
11.561ValAla: 11.561 ± 0.104
0.66ValCys: 0.66 ± 0.024
6.171ValAsp: 6.171 ± 0.072
4.671ValGlu: 4.671 ± 0.064
2.597ValPhe: 2.597 ± 0.044
7.477ValGly: 7.477 ± 0.079
1.64ValHis: 1.64 ± 0.034
4.525ValIle: 4.525 ± 0.069
1.796ValLys: 1.796 ± 0.039
8.249ValLeu: 8.249 ± 0.091
1.512ValMet: 1.512 ± 0.035
2.233ValAsn: 2.233 ± 0.04
4.427ValPro: 4.427 ± 0.064
1.815ValGln: 1.815 ± 0.033
5.606ValArg: 5.606 ± 0.075
5.266ValSer: 5.266 ± 0.055
5.745ValThr: 5.745 ± 0.069
8.882ValVal: 8.882 ± 0.09
0.998ValTrp: 0.998 ± 0.027
1.515ValTyr: 1.515 ± 0.035
0.0ValXaa: 0.0 ± 0.0
Trp
1.466TrpAla: 1.466 ± 0.035
0.133TrpCys: 0.133 ± 0.009
0.734TrpAsp: 0.734 ± 0.022
0.577TrpGlu: 0.577 ± 0.019
0.559TrpPhe: 0.559 ± 0.022
1.021TrpGly: 1.021 ± 0.032
0.349TrpHis: 0.349 ± 0.014
0.726TrpIle: 0.726 ± 0.024
0.337TrpLys: 0.337 ± 0.016
1.632TrpLeu: 1.632 ± 0.036
0.322TrpMet: 0.322 ± 0.016
0.394TrpAsn: 0.394 ± 0.017
0.707TrpPro: 0.707 ± 0.024
0.596TrpGln: 0.596 ± 0.02
1.224TrpArg: 1.224 ± 0.032
1.006TrpSer: 1.006 ± 0.025
0.889TrpThr: 0.889 ± 0.025
1.073TrpVal: 1.073 ± 0.029
0.378TrpTrp: 0.378 ± 0.016
0.315TrpTyr: 0.315 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.368TyrAla: 2.368 ± 0.042
0.19TyrCys: 0.19 ± 0.011
1.394TyrAsp: 1.394 ± 0.03
1.027TyrGlu: 1.027 ± 0.028
0.782TyrPhe: 0.782 ± 0.025
1.947TyrGly: 1.947 ± 0.038
0.389TyrHis: 0.389 ± 0.016
0.716TyrIle: 0.716 ± 0.023
0.38TyrLys: 0.38 ± 0.016
2.437TyrLeu: 2.437 ± 0.038
0.335TyrMet: 0.335 ± 0.017
0.504TyrAsn: 0.504 ± 0.02
1.226TyrPro: 1.226 ± 0.036
0.776TyrGln: 0.776 ± 0.027
1.937TyrArg: 1.937 ± 0.04
1.243TyrSer: 1.243 ± 0.029
1.266TyrThr: 1.266 ± 0.031
1.693TyrVal: 1.693 ± 0.034
0.367TyrTrp: 0.367 ± 0.015
0.528TyrTyr: 0.528 ± 0.022
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4419 proteins (1423384 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski