Amino acid dipepetide frequency for Arcticibacter pallidicorallinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.144AlaAla: 6.144 ± 0.096	0.649AlaCys: 0.649 ± 0.025	4.326AlaAsp: 4.326 ± 0.05	4.961AlaGlu: 4.961 ± 0.079	3.501AlaPhe: 3.501 ± 0.053	5.894AlaGly: 5.894 ± 0.076	1.216AlaHis: 1.216 ± 0.031	5.061AlaIle: 5.061 ± 0.073	4.291AlaLys: 4.291 ± 0.068	6.959AlaLeu: 6.959 ± 0.083	1.715AlaMet: 1.715 ± 0.044	3.502AlaAsn: 3.502 ± 0.059	2.309AlaPro: 2.309 ± 0.047	2.595AlaGln: 2.595 ± 0.048	2.977AlaArg: 2.977 ± 0.053	5.176AlaSer: 5.176 ± 0.072	3.723AlaThr: 3.723 ± 0.071	4.991AlaVal: 4.991 ± 0.064	0.826AlaTrp: 0.826 ± 0.028	2.811AlaTyr: 2.811 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.523CysAla: 0.523 ± 0.021	0.13CysCys: 0.13 ± 0.011	0.414CysAsp: 0.414 ± 0.019	0.375CysGlu: 0.375 ± 0.018	0.414CysPhe: 0.414 ± 0.02	0.603CysGly: 0.603 ± 0.027	0.184CysHis: 0.184 ± 0.014	0.606CysIle: 0.606 ± 0.023	0.422CysLys: 0.422 ± 0.019	0.753CysLeu: 0.753 ± 0.025	0.185CysMet: 0.185 ± 0.012	0.339CysAsn: 0.339 ± 0.018	0.316CysPro: 0.316 ± 0.017	0.211CysGln: 0.211 ± 0.013	0.375CysArg: 0.375 ± 0.018	0.573CysSer: 0.573 ± 0.021	0.384CysThr: 0.384 ± 0.019	0.483CysVal: 0.483 ± 0.02	0.088CysTrp: 0.088 ± 0.014	0.309CysTyr: 0.309 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.926AspAla: 3.926 ± 0.055	0.383AspCys: 0.383 ± 0.017	2.573AspAsp: 2.573 ± 0.055	3.5AspGlu: 3.5 ± 0.067	3.029AspPhe: 3.029 ± 0.053	3.857AspGly: 3.857 ± 0.075	0.982AspHis: 0.982 ± 0.033	4.04AspIle: 4.04 ± 0.057	3.55AspLys: 3.55 ± 0.058	5.387AspLeu: 5.387 ± 0.076	1.23AspMet: 1.23 ± 0.026	2.481AspAsn: 2.481 ± 0.041	2.403AspPro: 2.403 ± 0.046	1.893AspGln: 1.893 ± 0.045	2.542AspArg: 2.542 ± 0.047	3.185AspSer: 3.185 ± 0.058	2.458AspThr: 2.458 ± 0.044	3.587AspVal: 3.587 ± 0.057	0.767AspTrp: 0.767 ± 0.023	2.485AspTyr: 2.485 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	4.614GluAla: 4.614 ± 0.076	0.317GluCys: 0.317 ± 0.017	3.137GluAsp: 3.137 ± 0.061	4.204GluGlu: 4.204 ± 0.073	2.554GluPhe: 2.554 ± 0.049	4.037GluGly: 4.037 ± 0.055	1.161GluHis: 1.161 ± 0.033	4.492GluIle: 4.492 ± 0.062	4.54GluLys: 4.54 ± 0.073	5.953GluLeu: 5.953 ± 0.077	1.545GluMet: 1.545 ± 0.041	3.255GluAsn: 3.255 ± 0.058	1.775GluPro: 1.775 ± 0.039	2.401GluGln: 2.401 ± 0.047	3.136GluArg: 3.136 ± 0.059	3.526GluSer: 3.526 ± 0.06	3.02GluThr: 3.02 ± 0.056	4.059GluVal: 4.059 ± 0.056	0.709GluTrp: 0.709 ± 0.022	2.223GluTyr: 2.223 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	3.25PheAla: 3.25 ± 0.063	0.469PheCys: 0.469 ± 0.021	2.935PheAsp: 2.935 ± 0.05	2.765PheGlu: 2.765 ± 0.05	2.354PhePhe: 2.354 ± 0.057	3.449PheGly: 3.449 ± 0.052	0.884PheHis: 0.884 ± 0.029	3.225PheIle: 3.225 ± 0.056	3.054PheLys: 3.054 ± 0.046	4.37PheLeu: 4.37 ± 0.081	1.112PheMet: 1.112 ± 0.032	2.793PheAsn: 2.793 ± 0.052	1.769PhePro: 1.769 ± 0.037	1.456PheGln: 1.456 ± 0.039	2.197PheArg: 2.197 ± 0.043	3.972PheSer: 3.972 ± 0.065	2.699PheThr: 2.699 ± 0.05	2.858PheVal: 2.858 ± 0.052	0.574PheTrp: 0.574 ± 0.022	1.99PheTyr: 1.99 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	4.854GlyAla: 4.854 ± 0.071	0.599GlyCys: 0.599 ± 0.026	3.512GlyAsp: 3.512 ± 0.063	3.689GlyGlu: 3.689 ± 0.05	3.678GlyPhe: 3.678 ± 0.054	5.16GlyGly: 5.16 ± 0.101	1.281GlyHis: 1.281 ± 0.035	5.527GlyIle: 5.527 ± 0.072	5.169GlyLys: 5.169 ± 0.061	6.535GlyLeu: 6.535 ± 0.09	1.857GlyMet: 1.857 ± 0.04	3.558GlyAsn: 3.558 ± 0.068	1.72GlyPro: 1.72 ± 0.035	2.278GlyGln: 2.278 ± 0.05	3.102GlyArg: 3.102 ± 0.053	5.032GlySer: 5.032 ± 0.072	4.274GlyThr: 4.274 ± 0.089	4.678GlyVal: 4.678 ± 0.069	0.999GlyTrp: 0.999 ± 0.03	3.067GlyTyr: 3.067 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.31HisAla: 1.31 ± 0.032	0.179HisCys: 0.179 ± 0.013	0.919HisAsp: 0.919 ± 0.031	1.02HisGlu: 1.02 ± 0.028	1.046HisPhe: 1.046 ± 0.029	1.184HisGly: 1.184 ± 0.034	0.549HisHis: 0.549 ± 0.023	1.362HisIle: 1.362 ± 0.033	0.93HisLys: 0.93 ± 0.024	1.893HisLeu: 1.893 ± 0.042	0.355HisMet: 0.355 ± 0.019	0.907HisAsn: 0.907 ± 0.026	0.992HisPro: 0.992 ± 0.031	0.748HisGln: 0.748 ± 0.026	0.836HisArg: 0.836 ± 0.029	1.205HisSer: 1.205 ± 0.033	1.007HisThr: 1.007 ± 0.029	1.107HisVal: 1.107 ± 0.032	0.231HisTrp: 0.231 ± 0.012	0.86HisTyr: 0.86 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.615IleAla: 5.615 ± 0.078	0.695IleCys: 0.695 ± 0.027	4.045IleAsp: 4.045 ± 0.065	4.298IleGlu: 4.298 ± 0.067	2.986IlePhe: 2.986 ± 0.065	4.876IleGly: 4.876 ± 0.07	1.325IleHis: 1.325 ± 0.036	4.685IleIle: 4.685 ± 0.081	4.378IleLys: 4.378 ± 0.066	6.193IleLeu: 6.193 ± 0.086	1.406IleMet: 1.406 ± 0.033	3.656IleAsn: 3.656 ± 0.058	3.064IlePro: 3.064 ± 0.051	2.307IleGln: 2.307 ± 0.046	3.518IleArg: 3.518 ± 0.05	5.452IleSer: 5.452 ± 0.072	4.102IleThr: 4.102 ± 0.064	4.331IleVal: 4.331 ± 0.067	0.752IleTrp: 0.752 ± 0.026	2.54IleTyr: 2.54 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	4.99LysAla: 4.99 ± 0.068	0.304LysCys: 0.304 ± 0.017	3.941LysAsp: 3.941 ± 0.059	4.486LysGlu: 4.486 ± 0.062	2.445LysPhe: 2.445 ± 0.047	4.518LysGly: 4.518 ± 0.061	1.212LysHis: 1.212 ± 0.034	4.518LysIle: 4.518 ± 0.06	4.778LysLys: 4.778 ± 0.071	5.798LysLeu: 5.798 ± 0.065	1.701LysMet: 1.701 ± 0.036	3.517LysAsn: 3.517 ± 0.057	2.519LysPro: 2.519 ± 0.048	2.268LysGln: 2.268 ± 0.042	3.057LysArg: 3.057 ± 0.055	3.989LysSer: 3.989 ± 0.062	3.566LysThr: 3.566 ± 0.057	4.397LysVal: 4.397 ± 0.056	0.74LysTrp: 0.74 ± 0.026	2.532LysTyr: 2.532 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	6.766LeuAla: 6.766 ± 0.088	0.805LeuCys: 0.805 ± 0.029	4.789LeuAsp: 4.789 ± 0.068	5.366LeuGlu: 5.366 ± 0.078	4.616LeuPhe: 4.616 ± 0.076	5.998LeuGly: 5.998 ± 0.074	1.781LeuHis: 1.781 ± 0.04	6.618LeuIle: 6.618 ± 0.093	6.999LeuLys: 6.999 ± 0.082	9.153LeuLeu: 9.153 ± 0.124	2.228LeuMet: 2.228 ± 0.046	5.301LeuAsn: 5.301 ± 0.074	4.063LeuPro: 4.063 ± 0.058	3.471LeuGln: 3.471 ± 0.056	4.384LeuArg: 4.384 ± 0.063	7.528LeuSer: 7.528 ± 0.094	5.25LeuThr: 5.25 ± 0.077	5.591LeuVal: 5.591 ± 0.075	0.963LeuTrp: 0.963 ± 0.032	3.271LeuTyr: 3.271 ± 0.063	0.0LeuXaa: 0.0 ± 0.0
Met	1.823MetAla: 1.823 ± 0.039	0.15MetCys: 0.15 ± 0.01	1.234MetAsp: 1.234 ± 0.032	1.422MetGlu: 1.422 ± 0.036	0.851MetPhe: 0.851 ± 0.025	1.535MetGly: 1.535 ± 0.038	0.432MetHis: 0.432 ± 0.022	1.585MetIle: 1.585 ± 0.044	1.979MetLys: 1.979 ± 0.037	2.173MetLeu: 2.173 ± 0.043	0.608MetMet: 0.608 ± 0.021	1.355MetAsn: 1.355 ± 0.033	0.972MetPro: 0.972 ± 0.03	0.86MetGln: 0.86 ± 0.024	1.069MetArg: 1.069 ± 0.028	1.536MetSer: 1.536 ± 0.038	1.169MetThr: 1.169 ± 0.027	1.419MetVal: 1.419 ± 0.035	0.221MetTrp: 0.221 ± 0.014	0.699MetTyr: 0.699 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.683AsnAla: 3.683 ± 0.057	0.36AsnCys: 0.36 ± 0.02	2.512AsnAsp: 2.512 ± 0.045	2.906AsnGlu: 2.906 ± 0.057	2.477AsnPhe: 2.477 ± 0.046	3.788AsnGly: 3.788 ± 0.07	0.961AsnHis: 0.961 ± 0.028	3.695AsnIle: 3.695 ± 0.063	3.19AsnLys: 3.19 ± 0.051	4.698AsnLeu: 4.698 ± 0.063	1.141AsnMet: 1.141 ± 0.031	2.771AsnAsn: 2.771 ± 0.058	2.657AsnPro: 2.657 ± 0.053	1.938AsnGln: 1.938 ± 0.037	2.455AsnArg: 2.455 ± 0.046	3.27AsnSer: 3.27 ± 0.053	2.988AsnThr: 2.988 ± 0.053	3.262AsnVal: 3.262 ± 0.051	0.759AsnTrp: 0.759 ± 0.022	2.377AsnTyr: 2.377 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	3.091ProAla: 3.091 ± 0.055	0.236ProCys: 0.236 ± 0.017	2.545ProAsp: 2.545 ± 0.051	3.166ProGlu: 3.166 ± 0.05	1.927ProPhe: 1.927 ± 0.041	3.087ProGly: 3.087 ± 0.055	0.721ProHis: 0.721 ± 0.026	2.213ProIle: 2.213 ± 0.04	1.979ProLys: 1.979 ± 0.041	3.559ProLeu: 3.559 ± 0.055	0.836ProMet: 0.836 ± 0.025	1.69ProAsn: 1.69 ± 0.037	1.012ProPro: 1.012 ± 0.032	1.357ProGln: 1.357 ± 0.03	1.331ProArg: 1.331 ± 0.036	2.652ProSer: 2.652 ± 0.053	1.807ProThr: 1.807 ± 0.043	3.283ProVal: 3.283 ± 0.053	0.467ProTrp: 0.467 ± 0.021	1.501ProTyr: 1.501 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	2.642GlnAla: 2.642 ± 0.044	0.177GlnCys: 0.177 ± 0.013	1.742GlnAsp: 1.742 ± 0.043	2.175GlnGlu: 2.175 ± 0.051	1.531GlnPhe: 1.531 ± 0.034	2.144GlnGly: 2.144 ± 0.046	0.703GlnHis: 0.703 ± 0.026	2.439GlnIle: 2.439 ± 0.044	2.317GlnLys: 2.317 ± 0.044	3.533GlnLeu: 3.533 ± 0.056	0.838GlnMet: 0.838 ± 0.027	1.864GlnAsn: 1.864 ± 0.044	1.347GlnPro: 1.347 ± 0.034	1.598GlnGln: 1.598 ± 0.039	1.671GlnArg: 1.671 ± 0.035	2.281GlnSer: 2.281 ± 0.046	1.937GlnThr: 1.937 ± 0.037	2.356GlnVal: 2.356 ± 0.045	0.444GlnTrp: 0.444 ± 0.019	1.425GlnTyr: 1.425 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.915ArgAla: 2.915 ± 0.055	0.261ArgCys: 0.261 ± 0.017	2.494ArgAsp: 2.494 ± 0.044	2.865ArgGlu: 2.865 ± 0.052	2.49ArgPhe: 2.49 ± 0.045	2.684ArgGly: 2.684 ± 0.052	0.833ArgHis: 0.833 ± 0.028	3.431ArgIle: 3.431 ± 0.056	3.189ArgLys: 3.189 ± 0.052	4.469ArgLeu: 4.469 ± 0.063	1.199ArgMet: 1.199 ± 0.03	2.572ArgAsn: 2.572 ± 0.05	1.698ArgPro: 1.698 ± 0.039	1.625ArgGln: 1.625 ± 0.035	2.074ArgArg: 2.074 ± 0.048	2.947ArgSer: 2.947 ± 0.053	2.44ArgThr: 2.44 ± 0.046	2.886ArgVal: 2.886 ± 0.051	0.625ArgTrp: 0.625 ± 0.024	2.103ArgTyr: 2.103 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	5.277SerAla: 5.277 ± 0.068	0.585SerCys: 0.585 ± 0.022	3.556SerAsp: 3.556 ± 0.059	3.867SerGlu: 3.867 ± 0.073	3.781SerPhe: 3.781 ± 0.061	5.562SerGly: 5.562 ± 0.075	1.223SerHis: 1.223 ± 0.032	4.83SerIle: 4.83 ± 0.066	4.115SerLys: 4.115 ± 0.062	6.933SerLeu: 6.933 ± 0.086	1.484SerMet: 1.484 ± 0.039	3.25SerAsn: 3.25 ± 0.066	2.715SerPro: 2.715 ± 0.048	2.255SerGln: 2.255 ± 0.045	3.322SerArg: 3.322 ± 0.057	5.237SerSer: 5.237 ± 0.077	3.685SerThr: 3.685 ± 0.066	4.673SerVal: 4.673 ± 0.063	0.875SerTrp: 0.875 ± 0.028	2.939SerTyr: 2.939 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	4.177ThrAla: 4.177 ± 0.08	0.328ThrCys: 0.328 ± 0.018	3.173ThrAsp: 3.173 ± 0.051	3.204ThrGlu: 3.204 ± 0.052	2.587ThrPhe: 2.587 ± 0.054	4.659ThrGly: 4.659 ± 0.077	0.941ThrHis: 0.941 ± 0.03	3.805ThrIle: 3.805 ± 0.063	2.754ThrLys: 2.754 ± 0.044	5.205ThrLeu: 5.205 ± 0.07	1.009ThrMet: 1.009 ± 0.031	2.64ThrAsn: 2.64 ± 0.055	2.411ThrPro: 2.411 ± 0.047	1.765ThrGln: 1.765 ± 0.04	2.231ThrArg: 2.231 ± 0.044	3.799ThrSer: 3.799 ± 0.058	3.035ThrThr: 3.035 ± 0.068	3.691ThrVal: 3.691 ± 0.061	0.623ThrTrp: 0.623 ± 0.021	2.123ThrTyr: 2.123 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	4.608ValAla: 4.608 ± 0.065	0.606ValCys: 0.606 ± 0.026	3.492ValAsp: 3.492 ± 0.051	3.605ValGlu: 3.605 ± 0.057	3.216ValPhe: 3.216 ± 0.051	3.931ValGly: 3.931 ± 0.055	1.143ValHis: 1.143 ± 0.031	4.81ValIle: 4.81 ± 0.065	4.256ValLys: 4.256 ± 0.063	6.336ValLeu: 6.336 ± 0.083	1.47ValMet: 1.47 ± 0.037	3.45ValAsn: 3.45 ± 0.057	2.632ValPro: 2.632 ± 0.048	2.084ValGln: 2.084 ± 0.04	2.963ValArg: 2.963 ± 0.049	5.105ValSer: 5.105 ± 0.062	3.649ValThr: 3.649 ± 0.068	4.517ValVal: 4.517 ± 0.066	0.721ValTrp: 0.721 ± 0.028	2.534ValTyr: 2.534 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.789TrpAla: 0.789 ± 0.029	0.109TrpCys: 0.109 ± 0.009	0.714TrpAsp: 0.714 ± 0.028	0.691TrpGlu: 0.691 ± 0.024	0.592TrpPhe: 0.592 ± 0.021	0.838TrpGly: 0.838 ± 0.027	0.244TrpHis: 0.244 ± 0.014	0.814TrpIle: 0.814 ± 0.027	0.866TrpLys: 0.866 ± 0.028	1.126TrpLeu: 1.126 ± 0.035	0.372TrpMet: 0.372 ± 0.016	0.712TrpAsn: 0.712 ± 0.027	0.372TrpPro: 0.372 ± 0.02	0.484TrpGln: 0.484 ± 0.021	0.54TrpArg: 0.54 ± 0.02	0.782TrpSer: 0.782 ± 0.025	0.675TrpThr: 0.675 ± 0.025	0.705TrpVal: 0.705 ± 0.026	0.191TrpTrp: 0.191 ± 0.012	0.483TrpTyr: 0.483 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.633TyrAla: 2.633 ± 0.05	0.344TyrCys: 0.344 ± 0.019	2.205TyrAsp: 2.205 ± 0.047	2.092TyrGlu: 2.092 ± 0.047	2.1TyrPhe: 2.1 ± 0.041	2.763TyrGly: 2.763 ± 0.051	0.865TyrHis: 0.865 ± 0.028	2.468TyrIle: 2.468 ± 0.045	2.518TyrLys: 2.518 ± 0.043	3.917TyrLeu: 3.917 ± 0.061	0.804TyrMet: 0.804 ± 0.026	2.276TyrAsn: 2.276 ± 0.048	1.713TyrPro: 1.713 ± 0.041	1.569TyrGln: 1.569 ± 0.042	2.019TyrArg: 2.019 ± 0.044	2.916TyrSer: 2.916 ± 0.055	2.292TyrThr: 2.292 ± 0.05	2.255TyrVal: 2.255 ± 0.048	0.524TyrTrp: 0.524 ± 0.021	1.722TyrTyr: 1.722 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3484 proteins (1264185 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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