Amino acid dipepetide frequency for Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.222AlaAla: 8.222 ± 0.07	0.934AlaCys: 0.934 ± 0.015	3.902AlaAsp: 3.902 ± 0.03	4.978AlaGlu: 4.978 ± 0.04	2.824AlaPhe: 2.824 ± 0.028	5.435AlaGly: 5.435 ± 0.043	1.663AlaHis: 1.663 ± 0.02	4.053AlaIle: 4.053 ± 0.033	3.906AlaLys: 3.906 ± 0.034	7.019AlaLeu: 7.019 ± 0.051	1.731AlaMet: 1.731 ± 0.02	2.824AlaAsn: 2.824 ± 0.027	4.428AlaPro: 4.428 ± 0.04	3.118AlaGln: 3.118 ± 0.029	4.772AlaArg: 4.772 ± 0.031	7.016AlaSer: 7.016 ± 0.045	5.028AlaThr: 5.028 ± 0.037	4.846AlaVal: 4.846 ± 0.035	0.939AlaTrp: 0.939 ± 0.016	1.859AlaTyr: 1.859 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.875CysAla: 0.875 ± 0.015	0.258CysCys: 0.258 ± 0.009	0.628CysAsp: 0.628 ± 0.014	0.637CysGlu: 0.637 ± 0.014	0.526CysPhe: 0.526 ± 0.012	0.942CysGly: 0.942 ± 0.019	0.343CysHis: 0.343 ± 0.009	0.737CysIle: 0.737 ± 0.015	0.533CysLys: 0.533 ± 0.011	1.267CysLeu: 1.267 ± 0.019	0.27CysMet: 0.27 ± 0.008	0.432CysAsn: 0.432 ± 0.01	0.704CysPro: 0.704 ± 0.012	0.477CysGln: 0.477 ± 0.011	0.797CysArg: 0.797 ± 0.012	0.976CysSer: 0.976 ± 0.014	0.676CysThr: 0.676 ± 0.012	0.723CysVal: 0.723 ± 0.014	0.189CysTrp: 0.189 ± 0.006	0.35CysTyr: 0.35 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.192AspAla: 4.192 ± 0.032	0.614AspCys: 0.614 ± 0.013	4.321AspAsp: 4.321 ± 0.055	4.365AspGlu: 4.365 ± 0.046	2.117AspPhe: 2.117 ± 0.022	4.066AspGly: 4.066 ± 0.034	1.224AspHis: 1.224 ± 0.017	3.3AspIle: 3.3 ± 0.029	2.36AspLys: 2.36 ± 0.023	4.755AspLeu: 4.755 ± 0.032	1.245AspMet: 1.245 ± 0.016	2.042AspAsn: 2.042 ± 0.021	3.226AspPro: 3.226 ± 0.028	1.784AspGln: 1.784 ± 0.023	3.15AspArg: 3.15 ± 0.032	4.261AspSer: 4.261 ± 0.037	2.886AspThr: 2.886 ± 0.026	3.438AspVal: 3.438 ± 0.03	0.79AspTrp: 0.79 ± 0.014	1.512AspTyr: 1.512 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	4.923GluAla: 4.923 ± 0.035	0.675GluCys: 0.675 ± 0.014	4.082GluAsp: 4.082 ± 0.035	5.531GluGlu: 5.531 ± 0.06	1.969GluPhe: 1.969 ± 0.02	3.741GluGly: 3.741 ± 0.032	1.432GluHis: 1.432 ± 0.018	3.273GluIle: 3.273 ± 0.026	4.003GluLys: 4.003 ± 0.033	5.245GluLeu: 5.245 ± 0.043	1.506GluMet: 1.506 ± 0.019	2.552GluAsn: 2.552 ± 0.024	2.935GluPro: 2.935 ± 0.041	2.46GluGln: 2.46 ± 0.028	4.251GluArg: 4.251 ± 0.045	4.437GluSer: 4.437 ± 0.037	3.417GluThr: 3.417 ± 0.029	3.403GluVal: 3.403 ± 0.03	0.834GluTrp: 0.834 ± 0.017	1.708GluTyr: 1.708 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.713PheAla: 2.713 ± 0.029	0.566PheCys: 0.566 ± 0.011	2.164PheAsp: 2.164 ± 0.023	2.178PheGlu: 2.178 ± 0.025	1.493PhePhe: 1.493 ± 0.025	2.627PheGly: 2.627 ± 0.034	0.938PheHis: 0.938 ± 0.014	1.805PheIle: 1.805 ± 0.024	1.562PheLys: 1.562 ± 0.018	3.393PheLeu: 3.393 ± 0.036	0.733PheMet: 0.733 ± 0.013	1.42PheAsn: 1.42 ± 0.023	2.043PhePro: 2.043 ± 0.022	1.393PheGln: 1.393 ± 0.02	2.044PheArg: 2.044 ± 0.02	3.223PheSer: 3.223 ± 0.028	2.131PheThr: 2.131 ± 0.026	2.233PheVal: 2.233 ± 0.025	0.561PheTrp: 0.561 ± 0.013	1.066PheTyr: 1.066 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	4.841GlyAla: 4.841 ± 0.04	0.834GlyCys: 0.834 ± 0.017	3.702GlyAsp: 3.702 ± 0.031	3.837GlyGlu: 3.837 ± 0.036	2.601GlyPhe: 2.601 ± 0.029	6.12GlyGly: 6.12 ± 0.066	1.605GlyHis: 1.605 ± 0.023	3.429GlyIle: 3.429 ± 0.031	3.554GlyLys: 3.554 ± 0.035	5.541GlyLeu: 5.541 ± 0.037	1.647GlyMet: 1.647 ± 0.022	2.656GlyAsn: 2.656 ± 0.027	3.228GlyPro: 3.228 ± 0.034	2.446GlyGln: 2.446 ± 0.03	4.279GlyArg: 4.279 ± 0.037	5.78GlySer: 5.78 ± 0.045	3.774GlyThr: 3.774 ± 0.031	4.14GlyVal: 4.14 ± 0.035	1.055GlyTrp: 1.055 ± 0.017	2.003GlyTyr: 2.003 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.797HisAla: 1.797 ± 0.022	0.344HisCys: 0.344 ± 0.009	1.305HisAsp: 1.305 ± 0.016	1.282HisGlu: 1.282 ± 0.02	0.964HisPhe: 0.964 ± 0.015	1.69HisGly: 1.69 ± 0.023	0.997HisHis: 0.997 ± 0.022	1.302HisIle: 1.302 ± 0.018	0.942HisLys: 0.942 ± 0.015	2.287HisLeu: 2.287 ± 0.023	0.48HisMet: 0.48 ± 0.011	0.955HisAsn: 0.955 ± 0.016	1.87HisPro: 1.87 ± 0.023	1.17HisGln: 1.17 ± 0.02	1.692HisArg: 1.692 ± 0.021	2.168HisSer: 2.168 ± 0.028	1.32HisThr: 1.32 ± 0.019	1.391HisVal: 1.391 ± 0.019	0.3HisTrp: 0.3 ± 0.008	0.675HisTyr: 0.675 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.844IleAla: 3.844 ± 0.036	0.79IleCys: 0.79 ± 0.014	2.939IleAsp: 2.939 ± 0.025	2.97IleGlu: 2.97 ± 0.029	2.099IlePhe: 2.099 ± 0.024	3.029IleGly: 3.029 ± 0.028	1.269IleHis: 1.269 ± 0.017	2.777IleIle: 2.777 ± 0.033	2.279IleLys: 2.279 ± 0.025	4.763IleLeu: 4.763 ± 0.036	1.022IleMet: 1.022 ± 0.017	1.892IleAsn: 1.892 ± 0.02	3.404IlePro: 3.404 ± 0.03	1.97IleGln: 1.97 ± 0.021	2.986IleArg: 2.986 ± 0.029	4.511IleSer: 4.511 ± 0.034	2.91IleThr: 2.91 ± 0.028	2.96IleVal: 2.96 ± 0.029	0.705IleTrp: 0.705 ± 0.012	1.463IleTyr: 1.463 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.95LysAla: 3.95 ± 0.031	0.591LysCys: 0.591 ± 0.013	2.691LysAsp: 2.691 ± 0.028	3.532LysGlu: 3.532 ± 0.032	1.544LysPhe: 1.544 ± 0.019	3.005LysGly: 3.005 ± 0.032	1.173LysHis: 1.173 ± 0.017	2.483LysIle: 2.483 ± 0.027	3.664LysLys: 3.664 ± 0.056	4.315LysLeu: 4.315 ± 0.029	1.102LysMet: 1.102 ± 0.018	1.948LysAsn: 1.948 ± 0.02	2.972LysPro: 2.972 ± 0.032	1.999LysGln: 1.999 ± 0.027	3.765LysArg: 3.765 ± 0.037	3.89LysSer: 3.89 ± 0.037	2.754LysThr: 2.754 ± 0.028	2.688LysVal: 2.688 ± 0.029	0.627LysTrp: 0.627 ± 0.013	1.445LysTyr: 1.445 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.158LeuAla: 7.158 ± 0.054	1.207LeuCys: 1.207 ± 0.019	4.956LeuAsp: 4.956 ± 0.038	5.529LeuGlu: 5.529 ± 0.04	3.361LeuPhe: 3.361 ± 0.032	5.54LeuGly: 5.54 ± 0.039	2.32LeuHis: 2.32 ± 0.024	3.963LeuIle: 3.963 ± 0.034	4.474LeuLys: 4.474 ± 0.031	8.413LeuLeu: 8.413 ± 0.063	1.689LeuMet: 1.689 ± 0.019	3.293LeuAsn: 3.293 ± 0.028	5.496LeuPro: 5.496 ± 0.038	3.855LeuGln: 3.855 ± 0.033	5.838LeuArg: 5.838 ± 0.041	7.675LeuSer: 7.675 ± 0.042	4.719LeuThr: 4.719 ± 0.031	4.973LeuVal: 4.973 ± 0.04	1.088LeuTrp: 1.088 ± 0.018	2.296LeuTyr: 2.296 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.002MetAla: 2.002 ± 0.021	0.234MetCys: 0.234 ± 0.007	1.22MetAsp: 1.22 ± 0.015	1.384MetGlu: 1.384 ± 0.022	0.692MetPhe: 0.692 ± 0.012	1.467MetGly: 1.467 ± 0.018	0.464MetHis: 0.464 ± 0.009	1.022MetIle: 1.022 ± 0.016	1.135MetLys: 1.135 ± 0.016	1.746MetLeu: 1.746 ± 0.02	0.553MetMet: 0.553 ± 0.012	0.842MetAsn: 0.842 ± 0.016	1.18MetPro: 1.18 ± 0.019	0.841MetGln: 0.841 ± 0.016	1.277MetArg: 1.277 ± 0.016	1.835MetSer: 1.835 ± 0.02	1.255MetThr: 1.255 ± 0.016	1.24MetVal: 1.24 ± 0.016	0.247MetTrp: 0.247 ± 0.009	0.486MetTyr: 0.486 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.974AsnAla: 2.974 ± 0.027	0.48AsnCys: 0.48 ± 0.011	2.113AsnAsp: 2.113 ± 0.025	2.202AsnGlu: 2.202 ± 0.025	1.366AsnPhe: 1.366 ± 0.02	2.999AsnGly: 2.999 ± 0.032	0.978AsnHis: 0.978 ± 0.015	2.295AsnIle: 2.295 ± 0.021	1.707AsnLys: 1.707 ± 0.021	3.448AsnLeu: 3.448 ± 0.027	0.858AsnMet: 0.858 ± 0.014	2.027AsnAsn: 2.027 ± 0.033	2.74AsnPro: 2.74 ± 0.028	1.424AsnGln: 1.424 ± 0.022	2.211AsnArg: 2.211 ± 0.018	3.234AsnSer: 3.234 ± 0.028	2.291AsnThr: 2.291 ± 0.026	2.226AsnVal: 2.226 ± 0.02	0.491AsnTrp: 0.491 ± 0.011	1.066AsnTyr: 1.066 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.075ProAla: 5.075 ± 0.045	0.557ProCys: 0.557 ± 0.011	3.167ProAsp: 3.167 ± 0.029	3.796ProGlu: 3.796 ± 0.041	2.11ProPhe: 2.11 ± 0.024	3.907ProGly: 3.907 ± 0.03	1.562ProHis: 1.562 ± 0.024	2.723ProIle: 2.723 ± 0.026	2.733ProLys: 2.733 ± 0.029	4.942ProLeu: 4.942 ± 0.039	1.026ProMet: 1.026 ± 0.015	2.43ProAsn: 2.43 ± 0.025	6.137ProPro: 6.137 ± 0.087	2.696ProGln: 2.696 ± 0.037	3.638ProArg: 3.638 ± 0.035	6.738ProSer: 6.738 ± 0.057	4.377ProThr: 4.377 ± 0.05	3.466ProVal: 3.466 ± 0.03	0.648ProTrp: 0.648 ± 0.012	1.534ProTyr: 1.534 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.147GlnAla: 3.147 ± 0.033	0.449GlnCys: 0.449 ± 0.01	1.934GlnAsp: 1.934 ± 0.023	2.375GlnGlu: 2.375 ± 0.027	1.325GlnPhe: 1.325 ± 0.018	2.327GlnGly: 2.327 ± 0.028	1.224GlnHis: 1.224 ± 0.021	1.966GlnIle: 1.966 ± 0.023	2.14GlnLys: 2.14 ± 0.024	3.502GlnLeu: 3.502 ± 0.03	0.86GlnMet: 0.86 ± 0.015	1.796GlnAsn: 1.796 ± 0.022	2.835GlnPro: 2.835 ± 0.036	3.036GlnGln: 3.036 ± 0.078	2.844GlnArg: 2.844 ± 0.031	3.278GlnSer: 3.278 ± 0.035	2.227GlnThr: 2.227 ± 0.022	1.997GlnVal: 1.997 ± 0.019	0.495GlnTrp: 0.495 ± 0.01	1.094GlnTyr: 1.094 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.631ArgAla: 4.631 ± 0.033	0.767ArgCys: 0.767 ± 0.015	3.513ArgAsp: 3.513 ± 0.03	4.156ArgGlu: 4.156 ± 0.039	2.164ArgPhe: 2.164 ± 0.026	4.121ArgGly: 4.121 ± 0.038	1.666ArgHis: 1.666 ± 0.022	3.068ArgIle: 3.068 ± 0.029	3.744ArgLys: 3.744 ± 0.036	5.528ArgLeu: 5.528 ± 0.038	1.341ArgMet: 1.341 ± 0.016	2.554ArgAsn: 2.554 ± 0.024	3.682ArgPro: 3.682 ± 0.039	2.75ArgGln: 2.75 ± 0.025	5.691ArgArg: 5.691 ± 0.05	5.345ArgSer: 5.345 ± 0.044	3.411ArgThr: 3.411 ± 0.029	3.418ArgVal: 3.418 ± 0.025	0.914ArgTrp: 0.914 ± 0.015	1.702ArgTyr: 1.702 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	6.658SerAla: 6.658 ± 0.048	0.919SerCys: 0.919 ± 0.015	4.239SerAsp: 4.239 ± 0.034	4.384SerGlu: 4.384 ± 0.034	3.171SerPhe: 3.171 ± 0.03	5.676SerGly: 5.676 ± 0.038	2.256SerHis: 2.256 ± 0.027	4.256SerIle: 4.256 ± 0.025	4.037SerLys: 4.037 ± 0.038	7.527SerLeu: 7.527 ± 0.045	1.759SerMet: 1.759 ± 0.021	3.443SerAsn: 3.443 ± 0.034	6.299SerPro: 6.299 ± 0.06	3.598SerGln: 3.598 ± 0.031	5.705SerArg: 5.705 ± 0.046	10.366SerSer: 10.366 ± 0.084	6.112SerThr: 6.112 ± 0.048	4.546SerVal: 4.546 ± 0.038	1.025SerTrp: 1.025 ± 0.018	2.093SerTyr: 2.093 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.064ThrAla: 5.064 ± 0.037	0.729ThrCys: 0.729 ± 0.014	2.772ThrAsp: 2.772 ± 0.022	3.119ThrGlu: 3.119 ± 0.03	2.133ThrPhe: 2.133 ± 0.022	3.938ThrGly: 3.938 ± 0.035	1.351ThrHis: 1.351 ± 0.018	3.086ThrIle: 3.086 ± 0.022	2.641ThrLys: 2.641 ± 0.024	5.168ThrLeu: 5.168 ± 0.037	1.151ThrMet: 1.151 ± 0.017	2.222ThrAsn: 2.222 ± 0.021	4.582ThrPro: 4.582 ± 0.045	2.118ThrGln: 2.118 ± 0.026	3.304ThrArg: 3.304 ± 0.031	5.764ThrSer: 5.764 ± 0.043	4.836ThrThr: 4.836 ± 0.063	3.48ThrVal: 3.48 ± 0.03	0.686ThrTrp: 0.686 ± 0.013	1.537ThrTyr: 1.537 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.567ValAla: 4.567 ± 0.035	0.757ValCys: 0.757 ± 0.014	3.574ValAsp: 3.574 ± 0.029	3.836ValGlu: 3.836 ± 0.032	2.209ValPhe: 2.209 ± 0.025	3.775ValGly: 3.775 ± 0.033	1.363ValHis: 1.363 ± 0.017	2.881ValIle: 2.881 ± 0.029	2.863ValLys: 2.863 ± 0.029	5.182ValLeu: 5.182 ± 0.038	1.218ValMet: 1.218 ± 0.018	2.178ValAsn: 2.178 ± 0.027	3.377ValPro: 3.377 ± 0.029	2.129ValGln: 2.129 ± 0.024	3.357ValArg: 3.357 ± 0.029	4.542ValSer: 4.542 ± 0.034	3.273ValThr: 3.273 ± 0.029	3.88ValVal: 3.88 ± 0.037	0.8ValTrp: 0.8 ± 0.014	1.564ValTyr: 1.564 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.972TrpAla: 0.972 ± 0.016	0.232TrpCys: 0.232 ± 0.009	0.801TrpAsp: 0.801 ± 0.017	0.808TrpGlu: 0.808 ± 0.015	0.451TrpPhe: 0.451 ± 0.009	0.813TrpGly: 0.813 ± 0.016	0.319TrpHis: 0.319 ± 0.009	0.685TrpIle: 0.685 ± 0.012	0.787TrpLys: 0.787 ± 0.014	1.223TrpLeu: 1.223 ± 0.018	0.318TrpMet: 0.318 ± 0.009	0.567TrpAsn: 0.567 ± 0.013	0.528TrpPro: 0.528 ± 0.011	0.499TrpGln: 0.499 ± 0.012	0.931TrpArg: 0.931 ± 0.017	0.935TrpSer: 0.935 ± 0.013	0.779TrpThr: 0.779 ± 0.013	0.762TrpVal: 0.762 ± 0.014	0.236TrpTrp: 0.236 ± 0.008	0.348TrpTyr: 0.348 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.889TyrAla: 1.889 ± 0.022	0.404TyrCys: 0.404 ± 0.01	1.626TyrAsp: 1.626 ± 0.022	1.477TyrGlu: 1.477 ± 0.018	1.167TyrPhe: 1.167 ± 0.015	1.855TyrGly: 1.855 ± 0.024	0.785TyrHis: 0.785 ± 0.014	1.476TyrIle: 1.476 ± 0.023	1.073TyrLys: 1.073 ± 0.017	2.576TyrLeu: 2.576 ± 0.023	0.609TyrMet: 0.609 ± 0.012	1.057TyrAsn: 1.057 ± 0.016	1.596TyrPro: 1.596 ± 0.03	1.09TyrGln: 1.09 ± 0.019	1.635TyrArg: 1.635 ± 0.019	2.095TyrSer: 2.095 ± 0.024	1.507TyrThr: 1.507 ± 0.019	1.516TyrVal: 1.516 ± 0.02	0.366TyrTrp: 0.366 ± 0.01	0.889TyrTyr: 0.889 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10303 proteins (4560573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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