Amino acid dipepetide frequency for Oryza brachyantha

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.187AlaAla: 12.187 ± 0.07	1.55AlaCys: 1.55 ± 0.014	4.081AlaAsp: 4.081 ± 0.022	4.753AlaGlu: 4.753 ± 0.024	2.891AlaPhe: 2.891 ± 0.02	6.592AlaGly: 6.592 ± 0.03	1.678AlaHis: 1.678 ± 0.013	3.614AlaIle: 3.614 ± 0.02	3.724AlaLys: 3.724 ± 0.022	7.509AlaLeu: 7.509 ± 0.035	2.287AlaMet: 2.287 ± 0.014	2.564AlaAsn: 2.564 ± 0.017	4.402AlaPro: 4.402 ± 0.024	2.411AlaGln: 2.411 ± 0.015	5.096AlaArg: 5.096 ± 0.024	7.004AlaSer: 7.004 ± 0.028	4.508AlaThr: 4.508 ± 0.023	6.418AlaVal: 6.418 ± 0.03	0.955AlaTrp: 0.955 ± 0.01	1.908AlaTyr: 1.908 ± 0.014	0.037AlaXaa: 0.037 ± 0.002
Cys	1.284CysAla: 1.284 ± 0.012	0.619CysCys: 0.619 ± 0.01	0.877CysAsp: 0.877 ± 0.01	0.798CysGlu: 0.798 ± 0.008	0.828CysPhe: 0.828 ± 0.01	1.459CysGly: 1.459 ± 0.012	0.525CysHis: 0.525 ± 0.008	0.939CysIle: 0.939 ± 0.01	0.978CysLys: 0.978 ± 0.011	1.834CysLeu: 1.834 ± 0.014	0.483CysMet: 0.483 ± 0.009	0.726CysAsn: 0.726 ± 0.008	1.009CysPro: 1.009 ± 0.011	0.585CysGln: 0.585 ± 0.008	1.278CysArg: 1.278 ± 0.014	1.949CysSer: 1.949 ± 0.014	0.976CysThr: 0.976 ± 0.011	1.143CysVal: 1.143 ± 0.011	0.26CysTrp: 0.26 ± 0.005	0.534CysTyr: 0.534 ± 0.008	0.002CysXaa: 0.002 ± 0.0
Asp	4.584AspAla: 4.584 ± 0.026	0.906AspCys: 0.906 ± 0.009	4.142AspAsp: 4.142 ± 0.027	3.896AspGlu: 3.896 ± 0.025	1.936AspPhe: 1.936 ± 0.014	4.625AspGly: 4.625 ± 0.024	1.268AspHis: 1.268 ± 0.01	2.653AspIle: 2.653 ± 0.016	2.383AspLys: 2.383 ± 0.017	4.756AspLeu: 4.756 ± 0.024	1.416AspMet: 1.416 ± 0.01	1.79AspAsn: 1.79 ± 0.013	2.555AspPro: 2.555 ± 0.016	1.61AspGln: 1.61 ± 0.013	2.669AspArg: 2.669 ± 0.02	3.6AspSer: 3.6 ± 0.023	2.197AspThr: 2.197 ± 0.012	3.815AspVal: 3.815 ± 0.02	0.671AspTrp: 0.671 ± 0.008	1.382AspTyr: 1.382 ± 0.012	0.006AspXaa: 0.006 ± 0.001
Glu	5.213GluAla: 5.213 ± 0.027	0.861GluCys: 0.861 ± 0.01	3.566GluAsp: 3.566 ± 0.019	5.758GluGlu: 5.758 ± 0.034	1.97GluPhe: 1.97 ± 0.012	3.663GluGly: 3.663 ± 0.02	1.409GluHis: 1.409 ± 0.011	2.934GluIle: 2.934 ± 0.018	3.71GluLys: 3.71 ± 0.022	5.832GluLeu: 5.832 ± 0.029	1.672GluMet: 1.672 ± 0.013	2.242GluAsn: 2.242 ± 0.016	2.254GluPro: 2.254 ± 0.016	2.235GluGln: 2.235 ± 0.016	3.625GluArg: 3.625 ± 0.022	3.718GluSer: 3.718 ± 0.021	2.531GluThr: 2.531 ± 0.018	3.978GluVal: 3.978 ± 0.027	0.721GluTrp: 0.721 ± 0.008	1.463GluTyr: 1.463 ± 0.013	0.005GluXaa: 0.005 ± 0.001
Phe	2.713PheAla: 2.713 ± 0.016	0.806PheCys: 0.806 ± 0.009	2.127PheAsp: 2.127 ± 0.015	1.803PheGlu: 1.803 ± 0.013	1.808PhePhe: 1.808 ± 0.019	2.793PheGly: 2.793 ± 0.019	1.012PheHis: 1.012 ± 0.01	1.633PheIle: 1.633 ± 0.012	1.511PheLys: 1.511 ± 0.012	3.876PheLeu: 3.876 ± 0.023	0.887PheMet: 0.887 ± 0.008	1.298PheAsn: 1.298 ± 0.012	1.822PhePro: 1.822 ± 0.015	1.257PheGln: 1.257 ± 0.011	2.034PheArg: 2.034 ± 0.014	3.313PheSer: 3.313 ± 0.021	1.749PheThr: 1.749 ± 0.014	2.613PheVal: 2.613 ± 0.016	0.515PheTrp: 0.515 ± 0.007	1.072PheTyr: 1.072 ± 0.011	0.002PheXaa: 0.002 ± 0.001
Gly	5.935GlyAla: 5.935 ± 0.033	1.451GlyCys: 1.451 ± 0.011	4.085GlyAsp: 4.085 ± 0.02	4.066GlyGlu: 4.066 ± 0.023	2.798GlyPhe: 2.798 ± 0.018	8.255GlyGly: 8.255 ± 0.074	1.772GlyHis: 1.772 ± 0.015	3.099GlyIle: 3.099 ± 0.018	3.594GlyLys: 3.594 ± 0.021	5.874GlyLeu: 5.874 ± 0.024	1.654GlyMet: 1.654 ± 0.011	2.695GlyAsn: 2.695 ± 0.02	2.683GlyPro: 2.683 ± 0.019	2.185GlyGln: 2.185 ± 0.016	4.758GlyArg: 4.758 ± 0.026	5.912GlySer: 5.912 ± 0.028	3.356GlyThr: 3.356 ± 0.018	4.767GlyVal: 4.767 ± 0.027	0.995GlyTrp: 0.995 ± 0.011	2.03GlyTyr: 2.03 ± 0.017	0.037GlyXaa: 0.037 ± 0.002
His	1.896HisAla: 1.896 ± 0.013	0.548HisCys: 0.548 ± 0.007	1.282HisAsp: 1.282 ± 0.011	1.264HisGlu: 1.264 ± 0.011	0.924HisPhe: 0.924 ± 0.009	2.147HisGly: 2.147 ± 0.017	1.074HisHis: 1.074 ± 0.015	1.079HisIle: 1.079 ± 0.011	0.989HisLys: 0.989 ± 0.011	2.501HisLeu: 2.501 ± 0.016	0.578HisMet: 0.578 ± 0.007	0.818HisAsn: 0.818 ± 0.01	1.5HisPro: 1.5 ± 0.014	0.963HisGln: 0.963 ± 0.011	1.772HisArg: 1.772 ± 0.014	1.728HisSer: 1.728 ± 0.012	1.015HisThr: 1.015 ± 0.01	1.661HisVal: 1.661 ± 0.013	0.301HisTrp: 0.301 ± 0.005	0.651HisTyr: 0.651 ± 0.008	0.004HisXaa: 0.004 ± 0.001
Ile	3.465IleAla: 3.465 ± 0.022	0.974IleCys: 0.974 ± 0.01	2.523IleAsp: 2.523 ± 0.017	2.452IleGlu: 2.452 ± 0.017	1.801IlePhe: 1.801 ± 0.013	2.997IleGly: 2.997 ± 0.02	1.144IleHis: 1.144 ± 0.01	2.266IleIle: 2.266 ± 0.018	2.29IleLys: 2.29 ± 0.017	4.32IleLeu: 4.32 ± 0.023	1.024IleMet: 1.024 ± 0.009	1.72IleAsn: 1.72 ± 0.013	2.451IlePro: 2.451 ± 0.017	1.574IleGln: 1.574 ± 0.014	2.416IleArg: 2.416 ± 0.019	3.894IleSer: 3.894 ± 0.02	2.288IleThr: 2.288 ± 0.015	3.015IleVal: 3.015 ± 0.019	0.595IleTrp: 0.595 ± 0.008	1.307IleTyr: 1.307 ± 0.015	0.002IleXaa: 0.002 ± 0.0
Lys	3.734LysAla: 3.734 ± 0.021	0.821LysCys: 0.821 ± 0.01	2.693LysAsp: 2.693 ± 0.017	3.628LysGlu: 3.628 ± 0.023	1.633LysPhe: 1.633 ± 0.014	3.018LysGly: 3.018 ± 0.02	1.176LysHis: 1.176 ± 0.012	2.566LysIle: 2.566 ± 0.016	3.787LysLys: 3.787 ± 0.046	4.876LysLeu: 4.876 ± 0.024	1.284LysMet: 1.284 ± 0.01	2.045LysAsn: 2.045 ± 0.016	2.296LysPro: 2.296 ± 0.02	1.903LysGln: 1.903 ± 0.014	3.109LysArg: 3.109 ± 0.017	3.467LysSer: 3.467 ± 0.021	2.307LysThr: 2.307 ± 0.019	3.189LysVal: 3.189 ± 0.018	0.62LysTrp: 0.62 ± 0.007	1.332LysTyr: 1.332 ± 0.011	0.002LysXaa: 0.002 ± 0.0
Leu	7.803LeuAla: 7.803 ± 0.033	1.841LeuCys: 1.841 ± 0.015	4.975LeuAsp: 4.975 ± 0.029	5.58LeuGlu: 5.58 ± 0.029	3.465LeuPhe: 3.465 ± 0.02	5.823LeuGly: 5.823 ± 0.023	2.731LeuHis: 2.731 ± 0.017	3.745LeuIle: 3.745 ± 0.02	4.725LeuLys: 4.725 ± 0.025	10.381LeuLeu: 10.381 ± 0.046	2.044LeuMet: 2.044 ± 0.013	3.061LeuAsn: 3.061 ± 0.017	5.596LeuPro: 5.596 ± 0.027	4.006LeuGln: 4.006 ± 0.023	6.197LeuArg: 6.197 ± 0.028	7.712LeuSer: 7.712 ± 0.039	4.193LeuThr: 4.193 ± 0.024	6.503LeuVal: 6.503 ± 0.034	1.109LeuTrp: 1.109 ± 0.013	2.299LeuTyr: 2.299 ± 0.014	0.013LeuXaa: 0.013 ± 0.001
Met	2.75MetAla: 2.75 ± 0.014	0.36MetCys: 0.36 ± 0.006	1.473MetAsp: 1.473 ± 0.014	1.852MetGlu: 1.852 ± 0.014	0.781MetPhe: 0.781 ± 0.009	1.548MetGly: 1.548 ± 0.012	0.602MetHis: 0.602 ± 0.008	1.018MetIle: 1.018 ± 0.01	1.296MetLys: 1.296 ± 0.011	2.261MetLeu: 2.261 ± 0.014	0.681MetMet: 0.681 ± 0.009	0.873MetAsn: 0.873 ± 0.009	1.254MetPro: 1.254 ± 0.012	0.951MetGln: 0.951 ± 0.011	1.355MetArg: 1.355 ± 0.011	1.765MetSer: 1.765 ± 0.013	1.047MetThr: 1.047 ± 0.01	1.746MetVal: 1.746 ± 0.012	0.277MetTrp: 0.277 ± 0.005	0.616MetTyr: 0.616 ± 0.011	0.002MetXaa: 0.002 ± 0.0
Asn	2.605AsnAla: 2.605 ± 0.016	0.72AsnCys: 0.72 ± 0.009	1.707AsnAsp: 1.707 ± 0.015	1.851AsnGlu: 1.851 ± 0.014	1.446AsnPhe: 1.446 ± 0.012	2.794AsnGly: 2.794 ± 0.018	0.892AsnHis: 0.892 ± 0.008	1.999AsnIle: 1.999 ± 0.014	1.84AsnLys: 1.84 ± 0.014	3.666AsnLeu: 3.666 ± 0.022	1.005AsnMet: 1.005 ± 0.01	1.672AsnAsn: 1.672 ± 0.024	1.84AsnPro: 1.84 ± 0.014	1.293AsnGln: 1.293 ± 0.011	1.76AsnArg: 1.76 ± 0.012	2.924AsnSer: 2.924 ± 0.021	1.693AsnThr: 1.693 ± 0.013	2.271AsnVal: 2.271 ± 0.016	0.452AsnTrp: 0.452 ± 0.007	1.022AsnTyr: 1.022 ± 0.01	0.001AsnXaa: 0.001 ± 0.0
Pro	4.944ProAla: 4.944 ± 0.03	0.936ProCys: 0.936 ± 0.01	2.646ProAsp: 2.646 ± 0.017	3.213ProGlu: 3.213 ± 0.021	1.82ProPhe: 1.82 ± 0.014	3.284ProGly: 3.284 ± 0.02	1.214ProHis: 1.214 ± 0.011	1.873ProIle: 1.873 ± 0.014	2.214ProLys: 2.214 ± 0.02	4.421ProLeu: 4.421 ± 0.023	1.066ProMet: 1.066 ± 0.011	1.798ProAsn: 1.798 ± 0.015	5.329ProPro: 5.329 ± 0.056	1.708ProGln: 1.708 ± 0.017	3.313ProArg: 3.313 ± 0.021	5.142ProSer: 5.142 ± 0.027	2.7ProThr: 2.7 ± 0.017	3.383ProVal: 3.383 ± 0.019	0.686ProTrp: 0.686 ± 0.009	1.244ProTyr: 1.244 ± 0.012	0.034ProXaa: 0.034 ± 0.002
Gln	2.561GlnAla: 2.561 ± 0.018	0.601GlnCys: 0.601 ± 0.008	1.596GlnAsp: 1.596 ± 0.013	2.291GlnGlu: 2.291 ± 0.018	1.16GlnPhe: 1.16 ± 0.011	2.135GlnGly: 2.135 ± 0.014	0.989GlnHis: 0.989 ± 0.009	1.628GlnIle: 1.628 ± 0.014	1.883GlnLys: 1.883 ± 0.014	3.543GlnLeu: 3.543 ± 0.02	0.941GlnMet: 0.941 ± 0.011	1.361GlnAsn: 1.361 ± 0.012	1.877GlnPro: 1.877 ± 0.018	2.178GlnGln: 2.178 ± 0.029	2.265GlnArg: 2.265 ± 0.017	2.422GlnSer: 2.422 ± 0.018	1.467GlnThr: 1.467 ± 0.012	2.17GlnVal: 2.17 ± 0.013	0.442GlnTrp: 0.442 ± 0.006	0.889GlnTyr: 0.889 ± 0.01	0.003GlnXaa: 0.003 ± 0.001
Arg	4.797ArgAla: 4.797 ± 0.026	1.287ArgCys: 1.287 ± 0.013	2.909ArgAsp: 2.909 ± 0.02	3.48ArgGlu: 3.48 ± 0.024	2.184ArgPhe: 2.184 ± 0.015	4.223ArgGly: 4.223 ± 0.026	1.706ArgHis: 1.706 ± 0.014	2.577ArgIle: 2.577 ± 0.016	3.35ArgLys: 3.35 ± 0.021	5.819ArgLeu: 5.819 ± 0.028	1.538ArgMet: 1.538 ± 0.012	2.1ArgAsn: 2.1 ± 0.015	3.264ArgPro: 3.264 ± 0.019	2.124ArgGln: 2.124 ± 0.017	6.689ArgArg: 6.689 ± 0.05	4.849ArgSer: 4.849 ± 0.025	2.67ArgThr: 2.67 ± 0.017	3.75ArgVal: 3.75 ± 0.02	0.982ArgTrp: 0.982 ± 0.011	1.549ArgTyr: 1.549 ± 0.013	0.026ArgXaa: 0.026 ± 0.001
Ser	6.215SerAla: 6.215 ± 0.03	1.787SerCys: 1.787 ± 0.014	3.954SerAsp: 3.954 ± 0.023	3.985SerGlu: 3.985 ± 0.019	3.286SerPhe: 3.286 ± 0.02	5.908SerGly: 5.908 ± 0.031	1.802SerHis: 1.802 ± 0.015	3.696SerIle: 3.696 ± 0.022	3.812SerLys: 3.812 ± 0.025	7.635SerLeu: 7.635 ± 0.037	2.048SerMet: 2.048 ± 0.014	3.087SerAsn: 3.087 ± 0.021	4.749SerPro: 4.749 ± 0.028	2.475SerGln: 2.475 ± 0.018	4.655SerArg: 4.655 ± 0.023	10.084SerSer: 10.084 ± 0.053	4.442SerThr: 4.442 ± 0.025	4.84SerVal: 4.84 ± 0.022	1.15SerTrp: 1.15 ± 0.011	2.105SerTyr: 2.105 ± 0.013	0.013SerXaa: 0.013 ± 0.001
Thr	4.224ThrAla: 4.224 ± 0.021	0.952ThrCys: 0.952 ± 0.01	2.269ThrAsp: 2.269 ± 0.016	2.546ThrGlu: 2.546 ± 0.018	1.756ThrPhe: 1.756 ± 0.013	3.498ThrGly: 3.498 ± 0.021	0.974ThrHis: 0.974 ± 0.009	2.352ThrIle: 2.352 ± 0.016	2.274ThrLys: 2.274 ± 0.021	4.196ThrLeu: 4.196 ± 0.02	1.231ThrMet: 1.231 ± 0.01	1.779ThrAsn: 1.779 ± 0.015	2.719ThrPro: 2.719 ± 0.02	1.339ThrGln: 1.339 ± 0.012	2.56ThrArg: 2.56 ± 0.017	4.222ThrSer: 4.222 ± 0.022	3.048ThrThr: 3.048 ± 0.022	3.509ThrVal: 3.509 ± 0.02	0.612ThrTrp: 0.612 ± 0.007	1.321ThrTyr: 1.321 ± 0.013	0.008ThrXaa: 0.008 ± 0.001
Val	6.421ValAla: 6.421 ± 0.029	1.182ValCys: 1.182 ± 0.012	3.863ValAsp: 3.863 ± 0.021	4.074ValGlu: 4.074 ± 0.022	2.543ValPhe: 2.543 ± 0.018	4.477ValGly: 4.477 ± 0.024	1.717ValHis: 1.717 ± 0.013	2.922ValIle: 2.922 ± 0.02	3.154ValLys: 3.154 ± 0.02	6.663ValLeu: 6.663 ± 0.028	1.575ValMet: 1.575 ± 0.012	2.129ValAsn: 2.129 ± 0.014	3.572ValPro: 3.572 ± 0.021	2.308ValGln: 2.308 ± 0.015	3.773ValArg: 3.773 ± 0.017	4.969ValSer: 4.969 ± 0.022	3.293ValThr: 3.293 ± 0.019	5.624ValVal: 5.624 ± 0.031	0.801ValTrp: 0.801 ± 0.009	1.815ValTyr: 1.815 ± 0.014	0.008ValXaa: 0.008 ± 0.001
Trp	0.923TrpAla: 0.923 ± 0.01	0.271TrpCys: 0.271 ± 0.005	0.66TrpAsp: 0.66 ± 0.009	0.722TrpGlu: 0.722 ± 0.007	0.493TrpPhe: 0.493 ± 0.007	0.745TrpGly: 0.745 ± 0.009	0.314TrpHis: 0.314 ± 0.005	0.597TrpIle: 0.597 ± 0.008	0.744TrpLys: 0.744 ± 0.008	1.248TrpLeu: 1.248 ± 0.012	0.369TrpMet: 0.369 ± 0.005	0.583TrpAsn: 0.583 ± 0.007	0.596TrpPro: 0.596 ± 0.007	0.45TrpGln: 0.45 ± 0.007	1.029TrpArg: 1.029 ± 0.01	1.025TrpSer: 1.025 ± 0.01	0.645TrpThr: 0.645 ± 0.007	0.787TrpVal: 0.787 ± 0.009	0.275TrpTrp: 0.275 ± 0.014	0.331TrpTyr: 0.331 ± 0.006	0.002TrpXaa: 0.002 ± 0.0
Tyr	1.874TyrAla: 1.874 ± 0.014	0.614TyrCys: 0.614 ± 0.007	1.426TyrAsp: 1.426 ± 0.011	1.343TyrGlu: 1.343 ± 0.012	1.119TyrPhe: 1.119 ± 0.011	1.981TyrGly: 1.981 ± 0.015	0.697TyrHis: 0.697 ± 0.009	1.326TyrIle: 1.326 ± 0.014	1.227TyrLys: 1.227 ± 0.01	2.58TyrLeu: 2.58 ± 0.019	0.722TyrMet: 0.722 ± 0.008	1.109TyrAsn: 1.109 ± 0.011	1.169TyrPro: 1.169 ± 0.011	0.844TyrGln: 0.844 ± 0.009	1.491TyrArg: 1.491 ± 0.012	2.018TyrSer: 2.018 ± 0.014	1.256TyrThr: 1.256 ± 0.012	1.69TyrVal: 1.69 ± 0.015	0.385TyrTrp: 0.385 ± 0.006	0.926TyrTyr: 0.926 ± 0.01	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.039XaaAla: 0.039 ± 0.002	0.003XaaCys: 0.003 ± 0.001	0.005XaaAsp: 0.005 ± 0.001	0.006XaaGlu: 0.006 ± 0.001	0.003XaaPhe: 0.003 ± 0.0	0.035XaaGly: 0.035 ± 0.002	0.004XaaHis: 0.004 ± 0.001	0.002XaaIle: 0.002 ± 0.0	0.002XaaLys: 0.002 ± 0.0	0.01XaaLeu: 0.01 ± 0.001	0.004XaaMet: 0.004 ± 0.001	0.001XaaAsn: 0.001 ± 0.0	0.029XaaPro: 0.029 ± 0.002	0.003XaaGln: 0.003 ± 0.0	0.03XaaArg: 0.03 ± 0.002	0.011XaaSer: 0.011 ± 0.001	0.007XaaThr: 0.007 ± 0.001	0.011XaaVal: 0.011 ± 0.001	0.002XaaTrp: 0.002 ± 0.0	0.002XaaTyr: 0.002 ± 0.0	17.358XaaXaa: 17.358 ± 0.724

Statistics based on 31989 proteins (11295499 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---